PMC:7105881 / 28494-28918 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"896","span":{"begin":24,"end":29},"obj":"Gene"},{"id":"897","span":{"begin":31,"end":35},"obj":"Gene"},{"id":"898","span":{"begin":37,"end":41},"obj":"Gene"},{"id":"899","span":{"begin":43,"end":48},"obj":"Gene"},{"id":"957","span":{"begin":53,"end":57},"obj":"Species"},{"id":"958","span":{"begin":136,"end":140},"obj":"Species"},{"id":"959","span":{"begin":159,"end":167},"obj":"Species"},{"id":"960","span":{"begin":358,"end":366},"obj":"Species"},{"id":"1010","span":{"begin":76,"end":86},"obj":"CellLine"},{"id":"1011","span":{"begin":117,"end":120},"obj":"CellLine"},{"id":"1012","span":{"begin":204,"end":207},"obj":"CellLine"},{"id":"1013","span":{"begin":228,"end":238},"obj":"CellLine"},{"id":"1014","span":{"begin":335,"end":339},"obj":"CellLine"}],"attributes":[{"id":"A896","pred":"tao:has_database_id","subj":"896","obj":"Gene:3458"},{"id":"A897","pred":"tao:has_database_id","subj":"897","obj":"Gene:3558"},{"id":"A898","pred":"tao:has_database_id","subj":"898","obj":"Gene:3565"},{"id":"A899","pred":"tao:has_database_id","subj":"899","obj":"Gene:3586"},{"id":"A957","pred":"tao:has_database_id","subj":"957","obj":"Tax:10090"},{"id":"A958","pred":"tao:has_database_id","subj":"958","obj":"Tax:10090"},{"id":"A959","pred":"tao:has_database_id","subj":"959","obj":"Tax:694009"},{"id":"A960","pred":"tao:has_database_id","subj":"960","obj":"Tax:694009"},{"id":"A1010","pred":"tao:has_database_id","subj":"1010","obj":"CVCL:G580"},{"id":"A1011","pred":"tao:has_database_id","subj":"1011","obj":"CVCL:0213"},{"id":"A1012","pred":"tao:has_database_id","subj":"1012","obj":"CVCL:0213"},{"id":"A1013","pred":"tao:has_database_id","subj":"1013","obj":"CVCL:G580"},{"id":"A1014","pred":"tao:has_database_id","subj":"1014","obj":"CVCL:0063"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"lular immune responses (IFN-γ, IL-2, IL-4, IL-10) in mice Protect all (for RBD219-CHO) or majority (3/5, for RBD219-CHO) of vaccinated mice from challenge of SARS-CoV (GZ50 strain, 100 TCID50 for RBD193-CHO; 5 × 105 TCID50 for RBD219-CHO) with undetectable viral RNA or no, to reduced, viral load in lungs Du et al., 2009c, 2010\nRBD-293T protein Binds to SARS-CoV RBD-specific mAbs (neutralizing 24H8, 31H12, 35B5, 33G4, "}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T133","span":{"begin":31,"end":35},"obj":"Body_part"},{"id":"T134","span":{"begin":264,"end":267},"obj":"Body_part"},{"id":"T135","span":{"begin":301,"end":306},"obj":"Body_part"},{"id":"T136","span":{"begin":340,"end":347},"obj":"Body_part"}],"attributes":[{"id":"A133","pred":"fma_id","subj":"T133","obj":"http://purl.org/sig/ont/fma/fma84051"},{"id":"A134","pred":"fma_id","subj":"T134","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A135","pred":"fma_id","subj":"T135","obj":"http://purl.org/sig/ont/fma/fma68877"},{"id":"A136","pred":"fma_id","subj":"T136","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"lular immune responses (IFN-γ, IL-2, IL-4, IL-10) in mice Protect all (for RBD219-CHO) or majority (3/5, for RBD219-CHO) of vaccinated mice from challenge of SARS-CoV (GZ50 strain, 100 TCID50 for RBD193-CHO; 5 × 105 TCID50 for RBD219-CHO) with undetectable viral RNA or no, to reduced, viral load in lungs Du et al., 2009c, 2010\nRBD-293T protein Binds to SARS-CoV RBD-specific mAbs (neutralizing 24H8, 31H12, 35B5, 33G4, "}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T136","span":{"begin":159,"end":167},"obj":"Disease"},{"id":"T137","span":{"begin":358,"end":366},"obj":"Disease"}],"attributes":[{"id":"A136","pred":"mondo_id","subj":"T136","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A137","pred":"mondo_id","subj":"T137","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"lular immune responses (IFN-γ, IL-2, IL-4, IL-10) in mice Protect all (for RBD219-CHO) or majority (3/5, for RBD219-CHO) of vaccinated mice from challenge of SARS-CoV (GZ50 strain, 100 TCID50 for RBD193-CHO; 5 × 105 TCID50 for RBD219-CHO) with undetectable viral RNA or no, to reduced, viral load in lungs Du et al., 2009c, 2010\nRBD-293T protein Binds to SARS-CoV RBD-specific mAbs (neutralizing 24H8, 31H12, 35B5, 33G4, "}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T338","span":{"begin":31,"end":35},"obj":"http://purl.obolibrary.org/obo/PR_000001379"},{"id":"T339","span":{"begin":83,"end":86},"obj":"http://purl.obolibrary.org/obo/CLO_0002421"},{"id":"T340","span":{"begin":83,"end":86},"obj":"http://purl.obolibrary.org/obo/CLO_0052479"},{"id":"T341","span":{"begin":83,"end":86},"obj":"http://purl.obolibrary.org/obo/CLO_0052480"},{"id":"T342","span":{"begin":83,"end":86},"obj":"http://purl.obolibrary.org/obo/CLO_0052483"},{"id":"T343","span":{"begin":83,"end":86},"obj":"http://purl.obolibrary.org/obo/CLO_0052484"},{"id":"T344","span":{"begin":83,"end":86},"obj":"http://purl.obolibrary.org/obo/CLO_0052485"},{"id":"T345","span":{"begin":101,"end":104},"obj":"http://purl.obolibrary.org/obo/CLO_0001000"},{"id":"T346","span":{"begin":117,"end":120},"obj":"http://purl.obolibrary.org/obo/CLO_0002421"},{"id":"T347","span":{"begin":117,"end":120},"obj":"http://purl.obolibrary.org/obo/CLO_0052479"},{"id":"T348","span":{"begin":117,"end":120},"obj":"http://purl.obolibrary.org/obo/CLO_0052480"},{"id":"T349","span":{"begin":117,"end":120},"obj":"http://purl.obolibrary.org/obo/CLO_0052483"},{"id":"T350","span":{"begin":117,"end":120},"obj":"http://purl.obolibrary.org/obo/CLO_0052484"},{"id":"T351","span":{"begin":117,"end":120},"obj":"http://purl.obolibrary.org/obo/CLO_0052485"},{"id":"T352","span":{"begin":204,"end":207},"obj":"http://purl.obolibrary.org/obo/CLO_0002421"},{"id":"T353","span":{"begin":204,"end":207},"obj":"http://purl.obolibrary.org/obo/CLO_0052479"},{"id":"T354","span":{"begin":204,"end":207},"obj":"http://purl.obolibrary.org/obo/CLO_0052480"},{"id":"T355","span":{"begin":204,"end":207},"obj":"http://purl.obolibrary.org/obo/CLO_0052483"},{"id":"T356","span":{"begin":204,"end":207},"obj":"http://purl.obolibrary.org/obo/CLO_0052484"},{"id":"T357","span":{"begin":204,"end":207},"obj":"http://purl.obolibrary.org/obo/CLO_0052485"},{"id":"T358","span":{"begin":235,"end":238},"obj":"http://purl.obolibrary.org/obo/CLO_0002421"},{"id":"T359","span":{"begin":235,"end":238},"obj":"http://purl.obolibrary.org/obo/CLO_0052479"},{"id":"T360","span":{"begin":235,"end":238},"obj":"http://purl.obolibrary.org/obo/CLO_0052480"},{"id":"T361","span":{"begin":235,"end":238},"obj":"http://purl.obolibrary.org/obo/CLO_0052483"},{"id":"T362","span":{"begin":235,"end":238},"obj":"http://purl.obolibrary.org/obo/CLO_0052484"},{"id":"T363","span":{"begin":235,"end":238},"obj":"http://purl.obolibrary.org/obo/CLO_0052485"},{"id":"T364","span":{"begin":301,"end":306},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T365","span":{"begin":335,"end":339},"obj":"http://purl.obolibrary.org/obo/CLO_0050894"},{"id":"T366","span":{"begin":335,"end":339},"obj":"http://purl.obolibrary.org/obo/CLO_0051650"},{"id":"T367","span":{"begin":335,"end":339},"obj":"http://purl.obolibrary.org/obo/CLO_0052052"}],"text":"lular immune responses (IFN-γ, IL-2, IL-4, IL-10) in mice Protect all (for RBD219-CHO) or majority (3/5, for RBD219-CHO) of vaccinated mice from challenge of SARS-CoV (GZ50 strain, 100 TCID50 for RBD193-CHO; 5 × 105 TCID50 for RBD219-CHO) with undetectable viral RNA or no, to reduced, viral load in lungs Du et al., 2009c, 2010\nRBD-293T protein Binds to SARS-CoV RBD-specific mAbs (neutralizing 24H8, 31H12, 35B5, 33G4, "}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T132","span":{"begin":31,"end":33},"obj":"Chemical"},{"id":"T134","span":{"begin":37,"end":39},"obj":"Chemical"},{"id":"T136","span":{"begin":43,"end":45},"obj":"Chemical"},{"id":"T138","span":{"begin":340,"end":347},"obj":"Chemical"}],"attributes":[{"id":"A132","pred":"chebi_id","subj":"T132","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A133","pred":"chebi_id","subj":"T132","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A134","pred":"chebi_id","subj":"T134","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A135","pred":"chebi_id","subj":"T134","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A136","pred":"chebi_id","subj":"T136","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A137","pred":"chebi_id","subj":"T136","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A138","pred":"chebi_id","subj":"T138","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"lular immune responses (IFN-γ, IL-2, IL-4, IL-10) in mice Protect all (for RBD219-CHO) or majority (3/5, for RBD219-CHO) of vaccinated mice from challenge of SARS-CoV (GZ50 strain, 100 TCID50 for RBD193-CHO; 5 × 105 TCID50 for RBD219-CHO) with undetectable viral RNA or no, to reduced, viral load in lungs Du et al., 2009c, 2010\nRBD-293T protein Binds to SARS-CoV RBD-specific mAbs (neutralizing 24H8, 31H12, 35B5, 33G4, "}

{"project":"2_test","denotations":[{"id":"32265848-20374001-36511120","span":{"begin":326,"end":330},"obj":"20374001"}],"text":"lular immune responses (IFN-γ, IL-2, IL-4, IL-10) in mice Protect all (for RBD219-CHO) or majority (3/5, for RBD219-CHO) of vaccinated mice from challenge of SARS-CoV (GZ50 strain, 100 TCID50 for RBD193-CHO; 5 × 105 TCID50 for RBD219-CHO) with undetectable viral RNA or no, to reduced, viral load in lungs Du et al., 2009c, 2010\nRBD-293T protein Binds to SARS-CoV RBD-specific mAbs (neutralizing 24H8, 31H12, 35B5, 33G4, "}