PMC:7105881 / 25063-26043
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 757 | 47-55 | Species | denotes | SARS-CoV | Tax:694009 |
| 758 | 60-68 | Species | denotes | MERS-CoV | Tax:1335626 |
| 759 | 490-498 | Species | denotes | SARS-CoV | Tax:694009 |
| 760 | 503-511 | Species | denotes | MERS-CoV | Tax:1335626 |
| 761 | 544-548 | Species | denotes | mice | Tax:10090 |
| 762 | 554-559 | Species | denotes | human | Tax:9606 |
| 763 | 574-580 | Species | denotes | humans | Tax:9606 |
| 764 | 710-718 | Species | denotes | SARS-CoV | Tax:694009 |
| 765 | 723-731 | Species | denotes | MERS-CoV | Tax:1335626 |
| 766 | 759-767 | Species | denotes | SARS-CoV | Tax:694009 |
| 767 | 276-291 | Disease | denotes | viral infection | MESH:D001102 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T101 | 21-28 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T102 | 36-43 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T103 | 153-160 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T104 | 168-175 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T105 | 320-328 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
| T106 | 424-428 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T107 | 435-439 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T108 | 479-486 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T109 | 645-653 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T110 | 665-672 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T111 | 770-777 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T112 | 836-844 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
| T113 | 944-951 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T105 | 47-55 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T106 | 276-291 | Disease | denotes | viral infection | http://purl.obolibrary.org/obo/MONDO_0005108 |
| T107 | 282-291 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T108 | 490-498 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T109 | 710-718 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T110 | 759-767 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T264 | 176-179 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T265 | 234-239 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T266 | 422-428 | http://purl.obolibrary.org/obo/CL_0000236 | denotes | B-cell |
| T267 | 433-439 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T-cell |
| T268 | 554-559 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T269 | 560-568 | http://purl.obolibrary.org/obo/NCBITaxon_9443 | denotes | primates |
| T270 | 574-580 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | humans |
| T271 | 632-636 | http://purl.obolibrary.org/obo/CLO_0001185 | denotes | 2018 |
| T272 | 786-794 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptides |
| T273 | 872-879 | http://purl.obolibrary.org/obo/NCBITaxon_33208 | denotes | animals |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T110 | 21-28 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T111 | 36-43 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T112 | 153-160 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T113 | 168-175 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T114 | 479-486 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T115 | 645-653 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T116 | 665-672 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T117 | 770-777 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T118 | 786-794 | Chemical | denotes | peptides | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T119 | 944-951 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T42 | 276-291 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | viral infection |
| T43 | 333-358 | http://purl.obolibrary.org/obo/GO_0002456 | denotes | cellular immune responses |
| T44 | 333-358 | http://purl.obolibrary.org/obo/GO_0002449 | denotes | cellular immune responses |
| T45 | 333-358 | http://purl.obolibrary.org/obo/GO_0002443 | denotes | cellular immune responses |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32265848-16494977-36511108 | 372-376 | 16494977 | denotes | 2006 |
| 32265848-19523911-36511109 | 392-396 | 19523911 | denotes | 2009 |
| 32265848-16494977-36511110 | 594-598 | 16494977 | denotes | 2006 |
| 32265848-30558354-36511111 | 632-636 | 30558354 | denotes | 2018 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T150 | 0-143 | Sentence | denotes | In addition to the S protein, the N protein of SARS-CoV and MERS-CoV may serve as an additional target for the development of subunit vaccines. |
| T151 | 144-398 | Sentence | denotes | Unlike S protein, the N protein has no ability to elicit neutralizing antibodies to block virus-receptor interaction and neutralize viral infection, but it may induce specific antibody and cellular immune responses (Liu et al., 2006; Zheng et al., 2009). |
| T152 | 399-638 | Sentence | denotes | Several immunodominant B-cell and T-cell epitopes have been identified in the N protein of SARS-CoV and MERS-CoV, some of which are conserved in mice, non-human primates, and humans (Liu et al., 2006; Chan et al., 2011; Veit et al., 2018). |
| T153 | 639-749 | Sentence | denotes | Other proteins, such as M protein, can be used as potential targets of SARS-CoV and MERS-CoV subunit vaccines. |
| T154 | 750-980 | Sentence | denotes | Notably, SARS-CoV M protein-derived peptides have immunogenicity to induce high-titer antibody responses in the immunized animals (He et al., 2005b), suggesting the potential for utilizing this protein to develop subunit vaccines. |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T474 | 19-28 | PG_1 | denotes | S protein |
| T475 | 34-43 | PG_4 | denotes | N protein |
| T476 | 47-55 | SP_10 | denotes | SARS-CoV |
| T477 | 60-68 | SP_9 | denotes | MERS-CoV |
| T478 | 151-160 | PG_1 | denotes | S protein |
| T479 | 166-175 | PG_4 | denotes | N protein |
| T480 | 214-224 | GO:0042571 | denotes | antibodies |
| T481 | 234-239 | NCBITaxon:10239 | denotes | virus |
| T482 | 276-281 | NCBITaxon:10239 | denotes | viral |
| T483 | 320-328 | GO:0042571;GO:0016064 | denotes | antibody |
| T484 | 333-341 | GO:0051716 | denotes | cellular |
| T485 | 342-348 | UBERON:0002405;GO:0006955 | denotes | immune |
| T486 | 349-358 | GO:0006955 | denotes | responses |
| T487 | 422-428 | CL:0000236 | denotes | B-cell |
| T488 | 433-439 | CL:0000084;BV_24 | denotes | T-cell |
| T489 | 440-448 | BV_24 | denotes | epitopes |
| T490 | 477-486 | PG_4 | denotes | N protein |
| T491 | 490-498 | SP_10 | denotes | SARS-CoV |
| T492 | 503-511 | SP_9 | denotes | MERS-CoV |
| T493 | 544-548 | NCBITaxon:10088 | denotes | mice |
| T494 | 554-559 | SP_6;NCBITaxon:9606 | denotes | human |
| T495 | 560-568 | NCBITaxon:9443 | denotes | primates |
| T496 | 574-580 | NCBITaxon:9606 | denotes | humans |
| T497 | 663-672 | PG_3 | denotes | M protein |
| T498 | 710-718 | SP_10 | denotes | SARS-CoV |
| T499 | 723-731 | SP_9 | denotes | MERS-CoV |
| T500 | 759-767 | SP_10 | denotes | SARS-CoV |
| T501 | 768-777 | PG_3 | denotes | M protein |
| T502 | 800-814 | BV_15 | denotes | immunogenicity |
| T503 | 836-844 | GO:0042571 | denotes | antibody |
| T504 | 872-879 | NCBITaxon:33208 | denotes | animals |
| T74894 | 19-28 | PG_1 | denotes | S protein |
| T15381 | 34-43 | PG_4 | denotes | N protein |
| T26723 | 47-55 | SP_10 | denotes | SARS-CoV |
| T6926 | 60-68 | SP_9 | denotes | MERS-CoV |
| T67983 | 151-160 | PG_1 | denotes | S protein |
| T75080 | 166-175 | PG_4 | denotes | N protein |
| T89755 | 214-224 | GO:0042571 | denotes | antibodies |
| T63441 | 234-239 | NCBITaxon:10239 | denotes | virus |
| T21016 | 276-281 | NCBITaxon:10239 | denotes | viral |
| T45429 | 320-328 | GO:0042571;GO:0016064 | denotes | antibody |
| T61870 | 333-341 | GO:0051716 | denotes | cellular |
| T73627 | 342-348 | UBERON:0002405;GO:0006955 | denotes | immune |
| T35810 | 349-358 | GO:0006955 | denotes | responses |
| T13761 | 422-428 | CL:0000236 | denotes | B-cell |
| T95201 | 433-439 | CL:0000084;BV_24 | denotes | T-cell |
| T32620 | 440-448 | BV_24 | denotes | epitopes |
| T80163 | 477-486 | PG_4 | denotes | N protein |
| T92871 | 490-498 | SP_10 | denotes | SARS-CoV |
| T35029 | 503-511 | SP_9 | denotes | MERS-CoV |
| T13028 | 544-548 | NCBITaxon:10088 | denotes | mice |
| T50689 | 554-559 | SP_6;NCBITaxon:9606 | denotes | human |
| T33880 | 560-568 | NCBITaxon:9443 | denotes | primates |
| T32687 | 574-580 | NCBITaxon:9606 | denotes | humans |
| T42492 | 663-672 | PG_3 | denotes | M protein |
| T91348 | 710-718 | SP_10 | denotes | SARS-CoV |
| T25109 | 723-731 | SP_9 | denotes | MERS-CoV |
| T81541 | 759-767 | SP_10 | denotes | SARS-CoV |
| T69900 | 768-777 | PG_3 | denotes | M protein |
| T5444 | 800-814 | BV_15 | denotes | immunogenicity |
| T28747 | 836-844 | GO:0042571 | denotes | antibody |
| T58051 | 872-879 | NCBITaxon:33208 | denotes | animals |