PMC:7105881 / 15178-16154
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
507 | 129-160 | Gene | denotes | angiotensin-converting enzyme 2 | Gene:59272 |
508 | 162-166 | Gene | denotes | ACE2 | Gene:59272 |
509 | 315-319 | Gene | denotes | ACE2 | Gene:59272 |
510 | 475-479 | Gene | denotes | ACE2 | Gene:59272 |
511 | 540-544 | Gene | denotes | ACE2 | Gene:70008 |
512 | 780-784 | Gene | denotes | ACE2 | Gene:59272 |
513 | 922-926 | Gene | denotes | ACE2 | Gene:59272 |
514 | 11-20 | Species | denotes | HCoV-NL63 | Tax:277944 |
515 | 55-63 | Species | denotes | SARS-CoV | Tax:694009 |
516 | 469-474 | Species | denotes | human | Tax:9606 |
517 | 481-489 | Species | denotes | SARS-CoV | Tax:694009 |
518 | 534-539 | Species | denotes | mouse | Tax:10090 |
519 | 657-665 | Species | denotes | SARS-CoV | Tax:694009 |
520 | 720-724 | Species | denotes | CoVs | Tax:11118 |
521 | 757-761 | Species | denotes | CoVs | Tax:11118 |
522 | 774-779 | Species | denotes | human | Tax:9606 |
523 | 881-889 | Species | denotes | SARS-CoV | Tax:694009 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T72 | 198-202 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T73 | 306-313 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T74 | 492-499 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T75 | 519-523 | Body_part | denotes | palm | http://purl.org/sig/ont/fma/fma24920 |
T76 | 822-827 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T55 | 55-63 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T56 | 481-489 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T57 | 657-665 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T58 | 881-889 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T171 | 44-46 | http://purl.obolibrary.org/obo/CLO_0001022 | denotes | Li |
T172 | 44-46 | http://purl.obolibrary.org/obo/CLO_0007314 | denotes | Li |
T173 | 117-119 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T174 | 198-202 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T175 | 204-206 | http://purl.obolibrary.org/obo/CLO_0001022 | denotes | Li |
T176 | 204-206 | http://purl.obolibrary.org/obo/CLO_0007314 | denotes | Li |
T177 | 270-273 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T178 | 469-474 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T179 | 534-539 | http://purl.obolibrary.org/obo/CLO_0007836 | denotes | mouse |
T180 | 547-549 | http://purl.obolibrary.org/obo/CLO_0001022 | denotes | Li |
T181 | 547-549 | http://purl.obolibrary.org/obo/CLO_0007314 | denotes | Li |
T182 | 564-566 | http://purl.obolibrary.org/obo/CLO_0001022 | denotes | Li |
T183 | 564-566 | http://purl.obolibrary.org/obo/CLO_0007314 | denotes | Li |
T184 | 599-601 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T185 | 667-669 | http://purl.obolibrary.org/obo/CLO_0001022 | denotes | Li |
T186 | 667-669 | http://purl.obolibrary.org/obo/CLO_0007314 | denotes | Li |
T187 | 685-687 | http://purl.obolibrary.org/obo/CLO_0001022 | denotes | Li |
T188 | 685-687 | http://purl.obolibrary.org/obo/CLO_0007314 | denotes | Li |
T189 | 710-713 | http://purl.obolibrary.org/obo/NCBITaxon_9397 | denotes | bat |
T190 | 774-779 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T191 | 822-827 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T192 | 974-975 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T64 | 44-46 | Chemical | denotes | Li | http://purl.obolibrary.org/obo/CHEBI_30145 |
T65 | 129-140 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
T66 | 204-206 | Chemical | denotes | Li | http://purl.obolibrary.org/obo/CHEBI_30145 |
T67 | 306-313 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T68 | 492-499 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T69 | 547-549 | Chemical | denotes | Li | http://purl.obolibrary.org/obo/CHEBI_30145 |
T70 | 564-566 | Chemical | denotes | Li | http://purl.obolibrary.org/obo/CHEBI_30145 |
T71 | 667-669 | Chemical | denotes | Li | http://purl.obolibrary.org/obo/CHEBI_30145 |
T72 | 685-687 | Chemical | denotes | Li | http://purl.obolibrary.org/obo/CHEBI_30145 |
T73 | 829-831 | Chemical | denotes | Ge | http://purl.obolibrary.org/obo/CHEBI_30441 |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32265848-15897467-36511049 | 38-42 | 15897467 | denotes | 2005 |
32265848-25428871-36511050 | 48-52 | 25428871 | denotes | 2015 |
32265848-14647384-36511051 | 215-219 | 14647384 | denotes | 2003 |
32265848-28393837-36511052 | 447-451 | 28393837 | denotes | 2017 |
32265848-15452268-36511053 | 558-562 | 15452268 | denotes | 2004 |
32265848-18448527-36511054 | 568-572 | 18448527 | denotes | 2008 |
32265848-18448527-36511056 | 689-693 | 18448527 | denotes | 2008 |
32265848-27578435-36511057 | 695-699 | 27578435 | denotes | 2016 |
32265848-24172901-36511058 | 840-844 | 24172901 | denotes | 2013 |
32265848-29190287-36511059 | 857-861 | 29190287 | denotes | 2017 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T92 | 0-221 | Sentence | denotes | Similar to HCoV-NL63 (Hofmann et al., 2005; Li, 2015), SARS-CoV recognizes, through the RBD in the CTD region of its S1 subunit, angiotensin-converting enzyme 2 (ACE2) as the receptor on the target cell (Li et al., 2003). |
T93 | 222-314 | Sentence | denotes | The RBD (CTD) in two states (standing or lying) has been observed in the trimeric S protein. |
T94 | 315-453 | Sentence | denotes | ACE2 binds to standing RBD, specifically in the receptor-binding motif (RBM), keeping the RBD in the “standing” state (Yuan et al., 2017). |
T95 | 454-574 | Sentence | denotes | In addition to human ACE2, SARS-CoV S protein could also bind to palm civet and mouse ACE2s (Li et al., 2004; Li, 2008). |
T96 | 575-701 | Sentence | denotes | Mutations in the RBD of S1 subunit are required for cross-species transmission of SARS-CoV (Li et al., 2005c; Li, 2008, 2016). |
T97 | 702-863 | Sentence | denotes | Several bat SARSr-CoVs have been identified, and these CoVs can utilize human ACE2 as their receptor to bind the target cells (Ge et al., 2013; Hu et al., 2017). |
T98 | 864-976 | Sentence | denotes | The structure of SARS-CoV S trimer and RBD binding to the ACE2 receptor is shown in Supplementary Figures S1A,B. |
LitCovid-PMC-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T283 | 55-63 | SP_10 | denotes | SARS-CoV |
T284 | 129-160 | PG_10;PR:000003622 | denotes | angiotensin-converting enzyme 2 |
T285 | 162-166 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T286 | 304-313 | PG_1 | denotes | S protein |
T287 | 315-319 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T288 | 469-474 | SP_6;NCBITaxon:9606;PG_10 | denotes | human |
T289 | 475-479 | PG_10;PR:000003622 | denotes | ACE2 |
T290 | 481-489 | SP_10 | denotes | SARS-CoV |
T291 | 490-499 | PG_1 | denotes | S protein |
T292 | 519-529 | SP_5 | denotes | palm civet |
T293 | 534-539 | NCBITaxon:10088 | denotes | mouse |
T294 | 540-545 | G_3;PG_10;PR:000003622 | denotes | ACE2s |
T295 | 633-640 | NCBITaxon:species | denotes | species |
T296 | 657-665 | SP_10 | denotes | SARS-CoV |
T297 | 710-713 | SP_2 | denotes | bat |
T298 | 774-779 | SP_6;NCBITaxon:9606;PG_10 | denotes | human |
T299 | 780-784 | PG_10;PR:000003622 | denotes | ACE2 |
T300 | 881-889 | SP_10 | denotes | SARS-CoV |
T301 | 922-926 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T75904 | 55-63 | SP_10 | denotes | SARS-CoV |
T49457 | 129-160 | PG_10;PR:000003622 | denotes | angiotensin-converting enzyme 2 |
T35911 | 162-166 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T70634 | 304-313 | PG_1 | denotes | S protein |
T11366 | 315-319 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T55512 | 469-474 | SP_6;NCBITaxon:9606;PG_10 | denotes | human |
T44473 | 475-479 | PG_10;PR:000003622 | denotes | ACE2 |
T82875 | 481-489 | SP_10 | denotes | SARS-CoV |
T71569 | 490-499 | PG_1 | denotes | S protein |
T13510 | 519-529 | SP_5 | denotes | palm civet |
T75313 | 534-539 | NCBITaxon:10088 | denotes | mouse |
T61463 | 540-545 | G_3;PG_10;PR:000003622 | denotes | ACE2s |
T80982 | 633-640 | NCBITaxon:species | denotes | species |
T18234 | 657-665 | SP_10 | denotes | SARS-CoV |
T61271 | 710-713 | SP_2 | denotes | bat |
T69856 | 774-779 | SP_6;NCBITaxon:9606;PG_10 | denotes | human |
T52038 | 780-784 | PG_10;PR:000003622 | denotes | ACE2 |
T61108 | 881-889 | SP_10 | denotes | SARS-CoV |
T50014 | 922-926 | G_3;PG_10;PR:000003622 | denotes | ACE2 |