PMC:7103735 / 41801-42365 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T149","span":{"begin":122,"end":126},"obj":"Body_part"},{"id":"T150","span":{"begin":148,"end":152},"obj":"Body_part"},{"id":"T151","span":{"begin":271,"end":275},"obj":"Body_part"},{"id":"T152","span":{"begin":464,"end":468},"obj":"Body_part"},{"id":"T153","span":{"begin":485,"end":490},"obj":"Body_part"}],"attributes":[{"id":"A149","pred":"fma_id","subj":"T149","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A150","pred":"fma_id","subj":"T150","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A151","pred":"fma_id","subj":"T151","obj":"http://purl.org/sig/ont/fma/fma9712"},{"id":"A152","pred":"fma_id","subj":"T152","obj":"http://purl.org/sig/ont/fma/fma9712"},{"id":"A153","pred":"fma_id","subj":"T153","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"Apart from the potent suppression of interferon-mediated antiviral response, highly pathogenic HCoVs often induce massive cell death and cytopathy. Cell death is a double-edged sword that can play both antiviral and proviral roles during viral infection [68]. On the one hand, it is part of the host antiviral defence that provides a dead end to viral replication and infection, often at the price of pathological changes including inflammation [69]. On the other hand, dying and dead cells release a large number of virions, facilitating viral dissemination [70]."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T31","span":{"begin":271,"end":275},"obj":"Body_part"},{"id":"T32","span":{"begin":464,"end":468},"obj":"Body_part"}],"attributes":[{"id":"A31","pred":"uberon_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/UBERON_0002398"},{"id":"A32","pred":"uberon_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/UBERON_0002398"}],"text":"Apart from the potent suppression of interferon-mediated antiviral response, highly pathogenic HCoVs often induce massive cell death and cytopathy. Cell death is a double-edged sword that can play both antiviral and proviral roles during viral infection [68]. On the one hand, it is part of the host antiviral defence that provides a dead end to viral replication and infection, often at the price of pathological changes including inflammation [69]. On the other hand, dying and dead cells release a large number of virions, facilitating viral dissemination [70]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T391","span":{"begin":238,"end":253},"obj":"Disease"},{"id":"T392","span":{"begin":244,"end":253},"obj":"Disease"},{"id":"T393","span":{"begin":368,"end":377},"obj":"Disease"},{"id":"T394","span":{"begin":432,"end":444},"obj":"Disease"}],"attributes":[{"id":"A391","pred":"mondo_id","subj":"T391","obj":"http://purl.obolibrary.org/obo/MONDO_0005108"},{"id":"A392","pred":"mondo_id","subj":"T392","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A393","pred":"mondo_id","subj":"T393","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A394","pred":"mondo_id","subj":"T394","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"}],"text":"Apart from the potent suppression of interferon-mediated antiviral response, highly pathogenic HCoVs often induce massive cell death and cytopathy. Cell death is a double-edged sword that can play both antiviral and proviral roles during viral infection [68]. On the one hand, it is part of the host antiviral defence that provides a dead end to viral replication and infection, often at the price of pathological changes including inflammation [69]. On the other hand, dying and dead cells release a large number of virions, facilitating viral dissemination [70]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T465","span":{"begin":122,"end":126},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T466","span":{"begin":148,"end":152},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T467","span":{"begin":162,"end":163},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T468","span":{"begin":332,"end":333},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T469","span":{"begin":485,"end":490},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T470","span":{"begin":499,"end":500},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Apart from the potent suppression of interferon-mediated antiviral response, highly pathogenic HCoVs often induce massive cell death and cytopathy. Cell death is a double-edged sword that can play both antiviral and proviral roles during viral infection [68]. On the one hand, it is part of the host antiviral defence that provides a dead end to viral replication and infection, often at the price of pathological changes including inflammation [69]. On the other hand, dying and dead cells release a large number of virions, facilitating viral dissemination [70]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T145","span":{"begin":37,"end":47},"obj":"Chemical"},{"id":"T146","span":{"begin":57,"end":66},"obj":"Chemical"},{"id":"T147","span":{"begin":202,"end":211},"obj":"Chemical"},{"id":"T148","span":{"begin":300,"end":309},"obj":"Chemical"}],"attributes":[{"id":"A145","pred":"chebi_id","subj":"T145","obj":"http://purl.obolibrary.org/obo/CHEBI_52999"},{"id":"A146","pred":"chebi_id","subj":"T146","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"},{"id":"A147","pred":"chebi_id","subj":"T147","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"},{"id":"A148","pred":"chebi_id","subj":"T148","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"}],"text":"Apart from the potent suppression of interferon-mediated antiviral response, highly pathogenic HCoVs often induce massive cell death and cytopathy. Cell death is a double-edged sword that can play both antiviral and proviral roles during viral infection [68]. On the one hand, it is part of the host antiviral defence that provides a dead end to viral replication and infection, often at the price of pathological changes including inflammation [69]. On the other hand, dying and dead cells release a large number of virions, facilitating viral dissemination [70]."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T72","span":{"begin":57,"end":75},"obj":"http://purl.obolibrary.org/obo/GO_0051607"},{"id":"T73","span":{"begin":122,"end":132},"obj":"http://purl.obolibrary.org/obo/GO_0008219"},{"id":"T74","span":{"begin":148,"end":158},"obj":"http://purl.obolibrary.org/obo/GO_0008219"},{"id":"T75","span":{"begin":238,"end":253},"obj":"http://purl.obolibrary.org/obo/GO_0016032"},{"id":"T76","span":{"begin":346,"end":363},"obj":"http://purl.obolibrary.org/obo/GO_0019079"},{"id":"T77","span":{"begin":346,"end":363},"obj":"http://purl.obolibrary.org/obo/GO_0019058"},{"id":"T78","span":{"begin":432,"end":444},"obj":"http://purl.obolibrary.org/obo/GO_0006954"}],"text":"Apart from the potent suppression of interferon-mediated antiviral response, highly pathogenic HCoVs often induce massive cell death and cytopathy. Cell death is a double-edged sword that can play both antiviral and proviral roles during viral infection [68]. On the one hand, it is part of the host antiviral defence that provides a dead end to viral replication and infection, often at the price of pathological changes including inflammation [69]. On the other hand, dying and dead cells release a large number of virions, facilitating viral dissemination [70]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T346","span":{"begin":0,"end":147},"obj":"Sentence"},{"id":"T347","span":{"begin":148,"end":259},"obj":"Sentence"},{"id":"T348","span":{"begin":260,"end":450},"obj":"Sentence"},{"id":"T349","span":{"begin":451,"end":564},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Apart from the potent suppression of interferon-mediated antiviral response, highly pathogenic HCoVs often induce massive cell death and cytopathy. Cell death is a double-edged sword that can play both antiviral and proviral roles during viral infection [68]. On the one hand, it is part of the host antiviral defence that provides a dead end to viral replication and infection, often at the price of pathological changes including inflammation [69]. On the other hand, dying and dead cells release a large number of virions, facilitating viral dissemination [70]."}

{"project":"2_test","denotations":[{"id":"32172672-27501259-27782274","span":{"begin":255,"end":257},"obj":"27501259"},{"id":"32172672-24766891-27782275","span":{"begin":446,"end":448},"obj":"24766891"},{"id":"32172672-22402601-27782276","span":{"begin":560,"end":562},"obj":"22402601"}],"text":"Apart from the potent suppression of interferon-mediated antiviral response, highly pathogenic HCoVs often induce massive cell death and cytopathy. Cell death is a double-edged sword that can play both antiviral and proviral roles during viral infection [68]. On the one hand, it is part of the host antiviral defence that provides a dead end to viral replication and infection, often at the price of pathological changes including inflammation [69]. On the other hand, dying and dead cells release a large number of virions, facilitating viral dissemination [70]."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1196","span":{"begin":137,"end":146},"obj":"Disease"},{"id":"1197","span":{"begin":238,"end":253},"obj":"Disease"},{"id":"1198","span":{"begin":368,"end":377},"obj":"Disease"},{"id":"1199","span":{"begin":432,"end":444},"obj":"Disease"}],"attributes":[{"id":"A1196","pred":"tao:has_database_id","subj":"1196","obj":"MESH:C540770"},{"id":"A1197","pred":"tao:has_database_id","subj":"1197","obj":"MESH:D001102"},{"id":"A1198","pred":"tao:has_database_id","subj":"1198","obj":"MESH:D007239"},{"id":"A1199","pred":"tao:has_database_id","subj":"1199","obj":"MESH:D007249"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Apart from the potent suppression of interferon-mediated antiviral response, highly pathogenic HCoVs often induce massive cell death and cytopathy. Cell death is a double-edged sword that can play both antiviral and proviral roles during viral infection [68]. On the one hand, it is part of the host antiviral defence that provides a dead end to viral replication and infection, often at the price of pathological changes including inflammation [69]. On the other hand, dying and dead cells release a large number of virions, facilitating viral dissemination [70]."}

{"project":"MyTest","denotations":[{"id":"32172672-27501259-27782274","span":{"begin":255,"end":257},"obj":"27501259"},{"id":"32172672-24766891-27782275","span":{"begin":446,"end":448},"obj":"24766891"},{"id":"32172672-22402601-27782276","span":{"begin":560,"end":562},"obj":"22402601"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"Apart from the potent suppression of interferon-mediated antiviral response, highly pathogenic HCoVs often induce massive cell death and cytopathy. Cell death is a double-edged sword that can play both antiviral and proviral roles during viral infection [68]. On the one hand, it is part of the host antiviral defence that provides a dead end to viral replication and infection, often at the price of pathological changes including inflammation [69]. On the other hand, dying and dead cells release a large number of virions, facilitating viral dissemination [70]."}