PMC:7103735 / 23828-24758 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T102","span":{"begin":192,"end":202},"obj":"Body_part"},{"id":"T103","span":{"begin":282,"end":286},"obj":"Body_part"},{"id":"T104","span":{"begin":341,"end":352},"obj":"Body_part"},{"id":"T105","span":{"begin":844,"end":857},"obj":"Body_part"}],"attributes":[{"id":"A102","pred":"fma_id","subj":"T102","obj":"http://purl.org/sig/ont/fma/fma82740"},{"id":"A103","pred":"fma_id","subj":"T103","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A104","pred":"fma_id","subj":"T104","obj":"http://purl.org/sig/ont/fma/fma7647"},{"id":"A105","pred":"fma_id","subj":"T105","obj":"http://purl.org/sig/ont/fma/fma62870"}],"text":"The origins of another pair of human retroviruses named human T lymphotropic viruses 1 and 2 (HTLV-1 and HTLV-2) are also very similar and relevant to HCoVs [46]. HTLV-1 and HTLV-2 share ∼70% nucleotide sequence homology. Whereas HTLV-1 causes a highly lethal disease named adult T-cell leukaemia and another immune-mediated disorder of the spinal cord, the related virus HTLV-2 is largely non-pathogenic and non-oncogenic. Both viruses have counterparts in non-human primates and so are HTLV-3 and HTLV-4 newly discovered in Cameroonian hunters of non-human primates [47]. At least four cross-species transmission events of HTLVs have been identified, each of which involves a different species of primates. The spreading of HTLV-3 and HTLV-4 is very limited in humans, but HTLV-1 and HTLV-2 have infected millions of people. The infection of T lymphocytes with HTLV-2 provides a good example of asymptomatic infection in humans."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T27","span":{"begin":341,"end":352},"obj":"Body_part"}],"attributes":[{"id":"A27","pred":"uberon_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/UBERON_0002240"}],"text":"The origins of another pair of human retroviruses named human T lymphotropic viruses 1 and 2 (HTLV-1 and HTLV-2) are also very similar and relevant to HCoVs [46]. HTLV-1 and HTLV-2 share ∼70% nucleotide sequence homology. Whereas HTLV-1 causes a highly lethal disease named adult T-cell leukaemia and another immune-mediated disorder of the spinal cord, the related virus HTLV-2 is largely non-pathogenic and non-oncogenic. Both viruses have counterparts in non-human primates and so are HTLV-3 and HTLV-4 newly discovered in Cameroonian hunters of non-human primates [47]. At least four cross-species transmission events of HTLVs have been identified, each of which involves a different species of primates. The spreading of HTLV-3 and HTLV-4 is very limited in humans, but HTLV-1 and HTLV-2 have infected millions of people. The infection of T lymphocytes with HTLV-2 provides a good example of asymptomatic infection in humans."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T227","span":{"begin":94,"end":100},"obj":"Disease"},{"id":"T228","span":{"begin":163,"end":169},"obj":"Disease"},{"id":"T229","span":{"begin":230,"end":236},"obj":"Disease"},{"id":"T230","span":{"begin":274,"end":296},"obj":"Disease"},{"id":"T231","span":{"begin":325,"end":352},"obj":"Disease"},{"id":"T232","span":{"begin":775,"end":781},"obj":"Disease"},{"id":"T233","span":{"begin":831,"end":840},"obj":"Disease"},{"id":"T234","span":{"begin":910,"end":919},"obj":"Disease"}],"attributes":[{"id":"A227","pred":"mondo_id","subj":"T227","obj":"http://purl.obolibrary.org/obo/MONDO_0005801"},{"id":"A228","pred":"mondo_id","subj":"T228","obj":"http://purl.obolibrary.org/obo/MONDO_0005801"},{"id":"A229","pred":"mondo_id","subj":"T229","obj":"http://purl.obolibrary.org/obo/MONDO_0005801"},{"id":"A230","pred":"mondo_id","subj":"T230","obj":"http://purl.obolibrary.org/obo/MONDO_0019471"},{"id":"A231","pred":"mondo_id","subj":"T231","obj":"http://purl.obolibrary.org/obo/MONDO_0002545"},{"id":"A232","pred":"mondo_id","subj":"T232","obj":"http://purl.obolibrary.org/obo/MONDO_0005801"},{"id":"A233","pred":"mondo_id","subj":"T233","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A234","pred":"mondo_id","subj":"T234","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"The origins of another pair of human retroviruses named human T lymphotropic viruses 1 and 2 (HTLV-1 and HTLV-2) are also very similar and relevant to HCoVs [46]. HTLV-1 and HTLV-2 share ∼70% nucleotide sequence homology. Whereas HTLV-1 causes a highly lethal disease named adult T-cell leukaemia and another immune-mediated disorder of the spinal cord, the related virus HTLV-2 is largely non-pathogenic and non-oncogenic. Both viruses have counterparts in non-human primates and so are HTLV-3 and HTLV-4 newly discovered in Cameroonian hunters of non-human primates [47]. At least four cross-species transmission events of HTLVs have been identified, each of which involves a different species of primates. The spreading of HTLV-3 and HTLV-4 is very limited in humans, but HTLV-1 and HTLV-2 have infected millions of people. The infection of T lymphocytes with HTLV-2 provides a good example of asymptomatic infection in humans."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T316","span":{"begin":31,"end":36},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T317","span":{"begin":56,"end":61},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T318","span":{"begin":77,"end":84},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T319","span":{"begin":244,"end":245},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T320","span":{"begin":280,"end":286},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T321","span":{"begin":341,"end":352},"obj":"http://purl.obolibrary.org/obo/UBERON_0002240"},{"id":"T322","span":{"begin":366,"end":371},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T323","span":{"begin":429,"end":436},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T324","span":{"begin":462,"end":467},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T325","span":{"begin":468,"end":476},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9443"},{"id":"T326","span":{"begin":553,"end":558},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T327","span":{"begin":559,"end":567},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9443"},{"id":"T328","span":{"begin":676,"end":677},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T329","span":{"begin":699,"end":707},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9443"},{"id":"T330","span":{"begin":763,"end":769},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T331","span":{"begin":879,"end":880},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T332","span":{"begin":923,"end":929},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"}],"text":"The origins of another pair of human retroviruses named human T lymphotropic viruses 1 and 2 (HTLV-1 and HTLV-2) are also very similar and relevant to HCoVs [46]. HTLV-1 and HTLV-2 share ∼70% nucleotide sequence homology. Whereas HTLV-1 causes a highly lethal disease named adult T-cell leukaemia and another immune-mediated disorder of the spinal cord, the related virus HTLV-2 is largely non-pathogenic and non-oncogenic. Both viruses have counterparts in non-human primates and so are HTLV-3 and HTLV-4 newly discovered in Cameroonian hunters of non-human primates [47]. At least four cross-species transmission events of HTLVs have been identified, each of which involves a different species of primates. The spreading of HTLV-3 and HTLV-4 is very limited in humans, but HTLV-1 and HTLV-2 have infected millions of people. The infection of T lymphocytes with HTLV-2 provides a good example of asymptomatic infection in humans."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T53","span":{"begin":192,"end":202},"obj":"Chemical"}],"attributes":[{"id":"A53","pred":"chebi_id","subj":"T53","obj":"http://purl.obolibrary.org/obo/CHEBI_36976"}],"text":"The origins of another pair of human retroviruses named human T lymphotropic viruses 1 and 2 (HTLV-1 and HTLV-2) are also very similar and relevant to HCoVs [46]. HTLV-1 and HTLV-2 share ∼70% nucleotide sequence homology. Whereas HTLV-1 causes a highly lethal disease named adult T-cell leukaemia and another immune-mediated disorder of the spinal cord, the related virus HTLV-2 is largely non-pathogenic and non-oncogenic. Both viruses have counterparts in non-human primates and so are HTLV-3 and HTLV-4 newly discovered in Cameroonian hunters of non-human primates [47]. At least four cross-species transmission events of HTLVs have been identified, each of which involves a different species of primates. The spreading of HTLV-3 and HTLV-4 is very limited in humans, but HTLV-1 and HTLV-2 have infected millions of people. The infection of T lymphocytes with HTLV-2 provides a good example of asymptomatic infection in humans."}

{"project":"LitCovid-sentences","denotations":[{"id":"T194","span":{"begin":0,"end":162},"obj":"Sentence"},{"id":"T195","span":{"begin":163,"end":221},"obj":"Sentence"},{"id":"T196","span":{"begin":222,"end":423},"obj":"Sentence"},{"id":"T197","span":{"begin":424,"end":573},"obj":"Sentence"},{"id":"T198","span":{"begin":574,"end":708},"obj":"Sentence"},{"id":"T199","span":{"begin":709,"end":826},"obj":"Sentence"},{"id":"T200","span":{"begin":827,"end":930},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The origins of another pair of human retroviruses named human T lymphotropic viruses 1 and 2 (HTLV-1 and HTLV-2) are also very similar and relevant to HCoVs [46]. HTLV-1 and HTLV-2 share ∼70% nucleotide sequence homology. Whereas HTLV-1 causes a highly lethal disease named adult T-cell leukaemia and another immune-mediated disorder of the spinal cord, the related virus HTLV-2 is largely non-pathogenic and non-oncogenic. Both viruses have counterparts in non-human primates and so are HTLV-3 and HTLV-4 newly discovered in Cameroonian hunters of non-human primates [47]. At least four cross-species transmission events of HTLVs have been identified, each of which involves a different species of primates. The spreading of HTLV-3 and HTLV-4 is very limited in humans, but HTLV-1 and HTLV-2 have infected millions of people. The infection of T lymphocytes with HTLV-2 provides a good example of asymptomatic infection in humans."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T23","span":{"begin":287,"end":296},"obj":"Phenotype"}],"attributes":[{"id":"A23","pred":"hp_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/HP_0001909"}],"text":"The origins of another pair of human retroviruses named human T lymphotropic viruses 1 and 2 (HTLV-1 and HTLV-2) are also very similar and relevant to HCoVs [46]. HTLV-1 and HTLV-2 share ∼70% nucleotide sequence homology. Whereas HTLV-1 causes a highly lethal disease named adult T-cell leukaemia and another immune-mediated disorder of the spinal cord, the related virus HTLV-2 is largely non-pathogenic and non-oncogenic. Both viruses have counterparts in non-human primates and so are HTLV-3 and HTLV-4 newly discovered in Cameroonian hunters of non-human primates [47]. At least four cross-species transmission events of HTLVs have been identified, each of which involves a different species of primates. The spreading of HTLV-3 and HTLV-4 is very limited in humans, but HTLV-1 and HTLV-2 have infected millions of people. The infection of T lymphocytes with HTLV-2 provides a good example of asymptomatic infection in humans."}

{"project":"2_test","denotations":[{"id":"32172672-29052136-27782247","span":{"begin":158,"end":160},"obj":"29052136"}],"text":"The origins of another pair of human retroviruses named human T lymphotropic viruses 1 and 2 (HTLV-1 and HTLV-2) are also very similar and relevant to HCoVs [46]. HTLV-1 and HTLV-2 share ∼70% nucleotide sequence homology. Whereas HTLV-1 causes a highly lethal disease named adult T-cell leukaemia and another immune-mediated disorder of the spinal cord, the related virus HTLV-2 is largely non-pathogenic and non-oncogenic. Both viruses have counterparts in non-human primates and so are HTLV-3 and HTLV-4 newly discovered in Cameroonian hunters of non-human primates [47]. At least four cross-species transmission events of HTLVs have been identified, each of which involves a different species of primates. The spreading of HTLV-3 and HTLV-4 is very limited in humans, but HTLV-1 and HTLV-2 have infected millions of people. The infection of T lymphocytes with HTLV-2 provides a good example of asymptomatic infection in humans."}

{"project":"LitCovid-PubTator","denotations":[{"id":"760","span":{"begin":31,"end":36},"obj":"Species"},{"id":"761","span":{"begin":56,"end":61},"obj":"Species"},{"id":"762","span":{"begin":94,"end":100},"obj":"Species"},{"id":"763","span":{"begin":105,"end":111},"obj":"Species"},{"id":"764","span":{"begin":163,"end":169},"obj":"Species"},{"id":"765","span":{"begin":174,"end":180},"obj":"Species"},{"id":"766","span":{"begin":230,"end":236},"obj":"Species"},{"id":"767","span":{"begin":372,"end":378},"obj":"Species"},{"id":"768","span":{"begin":462,"end":467},"obj":"Species"},{"id":"769","span":{"begin":488,"end":494},"obj":"Species"},{"id":"770","span":{"begin":499,"end":505},"obj":"Species"},{"id":"771","span":{"begin":553,"end":558},"obj":"Species"},{"id":"772","span":{"begin":726,"end":732},"obj":"Species"},{"id":"773","span":{"begin":737,"end":743},"obj":"Species"},{"id":"774","span":{"begin":763,"end":769},"obj":"Species"},{"id":"775","span":{"begin":775,"end":781},"obj":"Species"},{"id":"776","span":{"begin":786,"end":792},"obj":"Species"},{"id":"777","span":{"begin":819,"end":825},"obj":"Species"},{"id":"778","span":{"begin":863,"end":869},"obj":"Species"},{"id":"779","span":{"begin":923,"end":929},"obj":"Species"},{"id":"780","span":{"begin":274,"end":296},"obj":"Disease"},{"id":"781","span":{"begin":798,"end":806},"obj":"Disease"},{"id":"782","span":{"begin":831,"end":840},"obj":"Disease"},{"id":"783","span":{"begin":910,"end":919},"obj":"Disease"}],"attributes":[{"id":"A760","pred":"tao:has_database_id","subj":"760","obj":"Tax:9606"},{"id":"A761","pred":"tao:has_database_id","subj":"761","obj":"Tax:9606"},{"id":"A762","pred":"tao:has_database_id","subj":"762","obj":"Tax:11908"},{"id":"A763","pred":"tao:has_database_id","subj":"763","obj":"Tax:11909"},{"id":"A764","pred":"tao:has_database_id","subj":"764","obj":"Tax:11908"},{"id":"A765","pred":"tao:has_database_id","subj":"765","obj":"Tax:11909"},{"id":"A766","pred":"tao:has_database_id","subj":"766","obj":"Tax:11908"},{"id":"A767","pred":"tao:has_database_id","subj":"767","obj":"Tax:11909"},{"id":"A768","pred":"tao:has_database_id","subj":"768","obj":"Tax:9606"},{"id":"A769","pred":"tao:has_database_id","subj":"769","obj":"Tax:28332"},{"id":"A770","pred":"tao:has_database_id","subj":"770","obj":"Tax:11725"},{"id":"A771","pred":"tao:has_database_id","subj":"771","obj":"Tax:9606"},{"id":"A772","pred":"tao:has_database_id","subj":"772","obj":"Tax:28332"},{"id":"A773","pred":"tao:has_database_id","subj":"773","obj":"Tax:11725"},{"id":"A774","pred":"tao:has_database_id","subj":"774","obj":"Tax:9606"},{"id":"A775","pred":"tao:has_database_id","subj":"775","obj":"Tax:11908"},{"id":"A776","pred":"tao:has_database_id","subj":"776","obj":"Tax:11909"},{"id":"A777","pred":"tao:has_database_id","subj":"777","obj":"Tax:9606"},{"id":"A778","pred":"tao:has_database_id","subj":"778","obj":"Tax:11909"},{"id":"A779","pred":"tao:has_database_id","subj":"779","obj":"Tax:9606"},{"id":"A780","pred":"tao:has_database_id","subj":"780","obj":"MESH:D015459"},{"id":"A781","pred":"tao:has_database_id","subj":"781","obj":"MESH:D007239"},{"id":"A782","pred":"tao:has_database_id","subj":"782","obj":"MESH:D007239"},{"id":"A783","pred":"tao:has_database_id","subj":"783","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The origins of another pair of human retroviruses named human T lymphotropic viruses 1 and 2 (HTLV-1 and HTLV-2) are also very similar and relevant to HCoVs [46]. HTLV-1 and HTLV-2 share ∼70% nucleotide sequence homology. Whereas HTLV-1 causes a highly lethal disease named adult T-cell leukaemia and another immune-mediated disorder of the spinal cord, the related virus HTLV-2 is largely non-pathogenic and non-oncogenic. Both viruses have counterparts in non-human primates and so are HTLV-3 and HTLV-4 newly discovered in Cameroonian hunters of non-human primates [47]. At least four cross-species transmission events of HTLVs have been identified, each of which involves a different species of primates. The spreading of HTLV-3 and HTLV-4 is very limited in humans, but HTLV-1 and HTLV-2 have infected millions of people. The infection of T lymphocytes with HTLV-2 provides a good example of asymptomatic infection in humans."}

{"project":"MyTest","denotations":[{"id":"32172672-29052136-27782247","span":{"begin":158,"end":160},"obj":"29052136"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"The origins of another pair of human retroviruses named human T lymphotropic viruses 1 and 2 (HTLV-1 and HTLV-2) are also very similar and relevant to HCoVs [46]. HTLV-1 and HTLV-2 share ∼70% nucleotide sequence homology. Whereas HTLV-1 causes a highly lethal disease named adult T-cell leukaemia and another immune-mediated disorder of the spinal cord, the related virus HTLV-2 is largely non-pathogenic and non-oncogenic. Both viruses have counterparts in non-human primates and so are HTLV-3 and HTLV-4 newly discovered in Cameroonian hunters of non-human primates [47]. At least four cross-species transmission events of HTLVs have been identified, each of which involves a different species of primates. The spreading of HTLV-3 and HTLV-4 is very limited in humans, but HTLV-1 and HTLV-2 have infected millions of people. The infection of T lymphocytes with HTLV-2 provides a good example of asymptomatic infection in humans."}