PMC:7103724 / 11429-12703 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T49","span":{"begin":76,"end":92},"obj":"Body_part"},{"id":"T50","span":{"begin":88,"end":92},"obj":"Body_part"},{"id":"T51","span":{"begin":187,"end":192},"obj":"Body_part"},{"id":"T52","span":{"begin":267,"end":271},"obj":"Body_part"},{"id":"T53","span":{"begin":497,"end":502},"obj":"Body_part"},{"id":"T54","span":{"begin":697,"end":702},"obj":"Body_part"},{"id":"T55","span":{"begin":722,"end":726},"obj":"Body_part"},{"id":"T56","span":{"begin":1056,"end":1060},"obj":"Body_part"},{"id":"T57","span":{"begin":1161,"end":1166},"obj":"Body_part"},{"id":"T58","span":{"begin":1235,"end":1240},"obj":"Body_part"}],"attributes":[{"id":"A49","pred":"fma_id","subj":"T49","obj":"http://purl.org/sig/ont/fma/fma62852"},{"id":"A50","pred":"fma_id","subj":"T50","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A51","pred":"fma_id","subj":"T51","obj":"http://purl.org/sig/ont/fma/fma63083"},{"id":"A52","pred":"fma_id","subj":"T52","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A53","pred":"fma_id","subj":"T53","obj":"http://purl.org/sig/ont/fma/fma9576"},{"id":"A54","pred":"fma_id","subj":"T54","obj":"http://purl.org/sig/ont/fma/fma9576"},{"id":"A55","pred":"fma_id","subj":"T55","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A56","pred":"fma_id","subj":"T56","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A57","pred":"fma_id","subj":"T57","obj":"http://purl.org/sig/ont/fma/fma9576"},{"id":"A58","pred":"fma_id","subj":"T58","obj":"http://purl.org/sig/ont/fma/fma9576"}],"text":"All the adult patients had normal (10/14, 71.4%) or decreased (4/14, 28.6%) white blood cell counts and 10 (71.4%) have lymphopenia. There were 4 (28.6%) patients had increased CRP, PCT, Serum amyloid A (SAA), D-dimer and IL-6, meanwhile, their CT-scan showed larger lung consolidation. Compared to children, there were only two (14.3%) patients showed increased CK-MB. Ferritin in the adult patients were higher than the children but most of them were normal (11/14, 78.6%). The imaging of adult chest was mix and the most common characters of imaging were pulmonary consolidation (50%), nodular shadow (42.9%), and ground glass opacity (GGO, 35.7%) (Figure 2). Four (28.6%) adults showed normal chest imaging.\nFigure 2. Lung computed tomography (CT) images of case 7 and case 8’s families. (A) The CT of their grandpa, who was 72-year-old and admitted for symptoms of high fever for 3 days. (B) CT scan of case their father, a 38-year-old patient admitted for symptoms of high fever, shortness of breath and fatigue for 10 days on his admission day. (C) Lung CT image of their mother, a 32-year-old female patient admitted for positive result of PCR (C). (D) Chest CT of the twins’ grandma, 65 years old and had fever, dry cough and chest pain for 6 days before admission."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T26","span":{"begin":82,"end":87},"obj":"Body_part"},{"id":"T27","span":{"begin":187,"end":192},"obj":"Body_part"},{"id":"T28","span":{"begin":267,"end":271},"obj":"Body_part"},{"id":"T29","span":{"begin":497,"end":502},"obj":"Body_part"},{"id":"T30","span":{"begin":697,"end":702},"obj":"Body_part"},{"id":"T31","span":{"begin":722,"end":726},"obj":"Body_part"},{"id":"T32","span":{"begin":1056,"end":1060},"obj":"Body_part"},{"id":"T33","span":{"begin":1161,"end":1166},"obj":"Body_part"},{"id":"T34","span":{"begin":1235,"end":1240},"obj":"Body_part"}],"attributes":[{"id":"A26","pred":"uberon_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A27","pred":"uberon_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/UBERON_0001977"},{"id":"A28","pred":"uberon_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A29","pred":"uberon_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/UBERON_0001443"},{"id":"A30","pred":"uberon_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/UBERON_0001443"},{"id":"A31","pred":"uberon_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A32","pred":"uberon_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A33","pred":"uberon_id","subj":"T33","obj":"http://purl.obolibrary.org/obo/UBERON_0001443"},{"id":"A34","pred":"uberon_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/UBERON_0001443"}],"text":"All the adult patients had normal (10/14, 71.4%) or decreased (4/14, 28.6%) white blood cell counts and 10 (71.4%) have lymphopenia. There were 4 (28.6%) patients had increased CRP, PCT, Serum amyloid A (SAA), D-dimer and IL-6, meanwhile, their CT-scan showed larger lung consolidation. Compared to children, there were only two (14.3%) patients showed increased CK-MB. Ferritin in the adult patients were higher than the children but most of them were normal (11/14, 78.6%). The imaging of adult chest was mix and the most common characters of imaging were pulmonary consolidation (50%), nodular shadow (42.9%), and ground glass opacity (GGO, 35.7%) (Figure 2). Four (28.6%) adults showed normal chest imaging.\nFigure 2. Lung computed tomography (CT) images of case 7 and case 8’s families. (A) The CT of their grandpa, who was 72-year-old and admitted for symptoms of high fever for 3 days. (B) CT scan of case their father, a 38-year-old patient admitted for symptoms of high fever, shortness of breath and fatigue for 10 days on his admission day. (C) Lung CT image of their mother, a 32-year-old female patient admitted for positive result of PCR (C). (D) Chest CT of the twins’ grandma, 65 years old and had fever, dry cough and chest pain for 6 days before admission."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T48","span":{"begin":120,"end":131},"obj":"Disease"},{"id":"T49","span":{"begin":182,"end":185},"obj":"Disease"},{"id":"T51","span":{"begin":193,"end":200},"obj":"Disease"},{"id":"T52","span":{"begin":363,"end":365},"obj":"Disease"}],"attributes":[{"id":"A48","pred":"mondo_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/MONDO_0003783"},{"id":"A49","pred":"mondo_id","subj":"T49","obj":"http://purl.obolibrary.org/obo/MONDO_0008296"},{"id":"A50","pred":"mondo_id","subj":"T49","obj":"http://purl.obolibrary.org/obo/MONDO_0015104"},{"id":"A51","pred":"mondo_id","subj":"T51","obj":"http://purl.obolibrary.org/obo/MONDO_0019065"},{"id":"A52","pred":"mondo_id","subj":"T52","obj":"http://purl.obolibrary.org/obo/MONDO_0017941"}],"text":"All the adult patients had normal (10/14, 71.4%) or decreased (4/14, 28.6%) white blood cell counts and 10 (71.4%) have lymphopenia. There were 4 (28.6%) patients had increased CRP, PCT, Serum amyloid A (SAA), D-dimer and IL-6, meanwhile, their CT-scan showed larger lung consolidation. Compared to children, there were only two (14.3%) patients showed increased CK-MB. Ferritin in the adult patients were higher than the children but most of them were normal (11/14, 78.6%). The imaging of adult chest was mix and the most common characters of imaging were pulmonary consolidation (50%), nodular shadow (42.9%), and ground glass opacity (GGO, 35.7%) (Figure 2). Four (28.6%) adults showed normal chest imaging.\nFigure 2. Lung computed tomography (CT) images of case 7 and case 8’s families. (A) The CT of their grandpa, who was 72-year-old and admitted for symptoms of high fever for 3 days. (B) CT scan of case their father, a 38-year-old patient admitted for symptoms of high fever, shortness of breath and fatigue for 10 days on his admission day. (C) Lung CT image of their mother, a 32-year-old female patient admitted for positive result of PCR (C). (D) Chest CT of the twins’ grandma, 65 years old and had fever, dry cough and chest pain for 6 days before admission."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T125","span":{"begin":82,"end":87},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T126","span":{"begin":88,"end":92},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T127","span":{"begin":201,"end":202},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T128","span":{"begin":267,"end":271},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T129","span":{"begin":267,"end":271},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T130","span":{"begin":366,"end":368},"obj":"http://purl.obolibrary.org/obo/PR_000010213"},{"id":"T131","span":{"begin":461,"end":463},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T132","span":{"begin":497,"end":502},"obj":"http://www.ebi.ac.uk/efo/EFO_0000965"},{"id":"T133","span":{"begin":697,"end":702},"obj":"http://www.ebi.ac.uk/efo/EFO_0000965"},{"id":"T134","span":{"begin":722,"end":726},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T135","span":{"begin":722,"end":726},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T136","span":{"begin":793,"end":794},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T137","span":{"begin":894,"end":895},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T138","span":{"begin":927,"end":928},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T139","span":{"begin":1056,"end":1060},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T140","span":{"begin":1056,"end":1060},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T141","span":{"begin":1087,"end":1088},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T142","span":{"begin":1101,"end":1107},"obj":"http://purl.obolibrary.org/obo/UBERON_0003100"},{"id":"T143","span":{"begin":1161,"end":1166},"obj":"http://www.ebi.ac.uk/efo/EFO_0000965"},{"id":"T144","span":{"begin":1235,"end":1240},"obj":"http://www.ebi.ac.uk/efo/EFO_0000965"}],"text":"All the adult patients had normal (10/14, 71.4%) or decreased (4/14, 28.6%) white blood cell counts and 10 (71.4%) have lymphopenia. There were 4 (28.6%) patients had increased CRP, PCT, Serum amyloid A (SAA), D-dimer and IL-6, meanwhile, their CT-scan showed larger lung consolidation. Compared to children, there were only two (14.3%) patients showed increased CK-MB. Ferritin in the adult patients were higher than the children but most of them were normal (11/14, 78.6%). The imaging of adult chest was mix and the most common characters of imaging were pulmonary consolidation (50%), nodular shadow (42.9%), and ground glass opacity (GGO, 35.7%) (Figure 2). Four (28.6%) adults showed normal chest imaging.\nFigure 2. Lung computed tomography (CT) images of case 7 and case 8’s families. (A) The CT of their grandpa, who was 72-year-old and admitted for symptoms of high fever for 3 days. (B) CT scan of case their father, a 38-year-old patient admitted for symptoms of high fever, shortness of breath and fatigue for 10 days on his admission day. (C) Lung CT image of their mother, a 32-year-old female patient admitted for positive result of PCR (C). (D) Chest CT of the twins’ grandma, 65 years old and had fever, dry cough and chest pain for 6 days before admission."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T43","span":{"begin":222,"end":224},"obj":"Chemical"},{"id":"T45","span":{"begin":370,"end":378},"obj":"Chemical"}],"attributes":[{"id":"A43","pred":"chebi_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A44","pred":"chebi_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A45","pred":"chebi_id","subj":"T45","obj":"http://purl.obolibrary.org/obo/CHEBI_82594"}],"text":"All the adult patients had normal (10/14, 71.4%) or decreased (4/14, 28.6%) white blood cell counts and 10 (71.4%) have lymphopenia. There were 4 (28.6%) patients had increased CRP, PCT, Serum amyloid A (SAA), D-dimer and IL-6, meanwhile, their CT-scan showed larger lung consolidation. Compared to children, there were only two (14.3%) patients showed increased CK-MB. Ferritin in the adult patients were higher than the children but most of them were normal (11/14, 78.6%). The imaging of adult chest was mix and the most common characters of imaging were pulmonary consolidation (50%), nodular shadow (42.9%), and ground glass opacity (GGO, 35.7%) (Figure 2). Four (28.6%) adults showed normal chest imaging.\nFigure 2. Lung computed tomography (CT) images of case 7 and case 8’s families. (A) The CT of their grandpa, who was 72-year-old and admitted for symptoms of high fever for 3 days. (B) CT scan of case their father, a 38-year-old patient admitted for symptoms of high fever, shortness of breath and fatigue for 10 days on his admission day. (C) Lung CT image of their mother, a 32-year-old female patient admitted for positive result of PCR (C). (D) Chest CT of the twins’ grandma, 65 years old and had fever, dry cough and chest pain for 6 days before admission."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T7","span":{"begin":363,"end":368},"obj":"http://purl.obolibrary.org/obo/GO_0004111"}],"text":"All the adult patients had normal (10/14, 71.4%) or decreased (4/14, 28.6%) white blood cell counts and 10 (71.4%) have lymphopenia. There were 4 (28.6%) patients had increased CRP, PCT, Serum amyloid A (SAA), D-dimer and IL-6, meanwhile, their CT-scan showed larger lung consolidation. Compared to children, there were only two (14.3%) patients showed increased CK-MB. Ferritin in the adult patients were higher than the children but most of them were normal (11/14, 78.6%). The imaging of adult chest was mix and the most common characters of imaging were pulmonary consolidation (50%), nodular shadow (42.9%), and ground glass opacity (GGO, 35.7%) (Figure 2). Four (28.6%) adults showed normal chest imaging.\nFigure 2. Lung computed tomography (CT) images of case 7 and case 8’s families. (A) The CT of their grandpa, who was 72-year-old and admitted for symptoms of high fever for 3 days. (B) CT scan of case their father, a 38-year-old patient admitted for symptoms of high fever, shortness of breath and fatigue for 10 days on his admission day. (C) Lung CT image of their mother, a 32-year-old female patient admitted for positive result of PCR (C). (D) Chest CT of the twins’ grandma, 65 years old and had fever, dry cough and chest pain for 6 days before admission."}

{"project":"LitCovid-sentences","denotations":[{"id":"T97","span":{"begin":0,"end":132},"obj":"Sentence"},{"id":"T98","span":{"begin":133,"end":286},"obj":"Sentence"},{"id":"T99","span":{"begin":287,"end":369},"obj":"Sentence"},{"id":"T100","span":{"begin":370,"end":475},"obj":"Sentence"},{"id":"T101","span":{"begin":476,"end":662},"obj":"Sentence"},{"id":"T102","span":{"begin":663,"end":711},"obj":"Sentence"},{"id":"T103","span":{"begin":712,"end":721},"obj":"Sentence"},{"id":"T104","span":{"begin":722,"end":1274},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"All the adult patients had normal (10/14, 71.4%) or decreased (4/14, 28.6%) white blood cell counts and 10 (71.4%) have lymphopenia. There were 4 (28.6%) patients had increased CRP, PCT, Serum amyloid A (SAA), D-dimer and IL-6, meanwhile, their CT-scan showed larger lung consolidation. Compared to children, there were only two (14.3%) patients showed increased CK-MB. Ferritin in the adult patients were higher than the children but most of them were normal (11/14, 78.6%). The imaging of adult chest was mix and the most common characters of imaging were pulmonary consolidation (50%), nodular shadow (42.9%), and ground glass opacity (GGO, 35.7%) (Figure 2). Four (28.6%) adults showed normal chest imaging.\nFigure 2. Lung computed tomography (CT) images of case 7 and case 8’s families. (A) The CT of their grandpa, who was 72-year-old and admitted for symptoms of high fever for 3 days. (B) CT scan of case their father, a 38-year-old patient admitted for symptoms of high fever, shortness of breath and fatigue for 10 days on his admission day. (C) Lung CT image of their mother, a 32-year-old female patient admitted for positive result of PCR (C). (D) Chest CT of the twins’ grandma, 65 years old and had fever, dry cough and chest pain for 6 days before admission."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T28","span":{"begin":120,"end":131},"obj":"Phenotype"},{"id":"T29","span":{"begin":875,"end":880},"obj":"Phenotype"},{"id":"T30","span":{"begin":979,"end":984},"obj":"Phenotype"},{"id":"T31","span":{"begin":986,"end":1005},"obj":"Phenotype"},{"id":"T32","span":{"begin":1010,"end":1017},"obj":"Phenotype"},{"id":"T33","span":{"begin":1214,"end":1219},"obj":"Phenotype"},{"id":"T34","span":{"begin":1221,"end":1230},"obj":"Phenotype"},{"id":"T35","span":{"begin":1235,"end":1245},"obj":"Phenotype"}],"attributes":[{"id":"A28","pred":"hp_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/HP_0001888"},{"id":"A29","pred":"hp_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/HP_0001945"},{"id":"A30","pred":"hp_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/HP_0001945"},{"id":"A31","pred":"hp_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/HP_0002098"},{"id":"A32","pred":"hp_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/HP_0012378"},{"id":"A33","pred":"hp_id","subj":"T33","obj":"http://purl.obolibrary.org/obo/HP_0001945"},{"id":"A34","pred":"hp_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/HP_0031246"},{"id":"A35","pred":"hp_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/HP_0100749"}],"text":"All the adult patients had normal (10/14, 71.4%) or decreased (4/14, 28.6%) white blood cell counts and 10 (71.4%) have lymphopenia. There were 4 (28.6%) patients had increased CRP, PCT, Serum amyloid A (SAA), D-dimer and IL-6, meanwhile, their CT-scan showed larger lung consolidation. Compared to children, there were only two (14.3%) patients showed increased CK-MB. Ferritin in the adult patients were higher than the children but most of them were normal (11/14, 78.6%). The imaging of adult chest was mix and the most common characters of imaging were pulmonary consolidation (50%), nodular shadow (42.9%), and ground glass opacity (GGO, 35.7%) (Figure 2). Four (28.6%) adults showed normal chest imaging.\nFigure 2. Lung computed tomography (CT) images of case 7 and case 8’s families. (A) The CT of their grandpa, who was 72-year-old and admitted for symptoms of high fever for 3 days. (B) CT scan of case their father, a 38-year-old patient admitted for symptoms of high fever, shortness of breath and fatigue for 10 days on his admission day. (C) Lung CT image of their mother, a 32-year-old female patient admitted for positive result of PCR (C). (D) Chest CT of the twins’ grandma, 65 years old and had fever, dry cough and chest pain for 6 days before admission."}

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