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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 507-521 Body_part denotes immunoglobulin http://purl.org/sig/ont/fma/fma62871
T2 547-554 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T3 2862-2876 Body_part denotes immunoglobulin http://purl.org/sig/ont/fma/fma62871
T4 2909-2916 Body_part denotes heparin http://purl.org/sig/ont/fma/fma82839
T5 3066-3071 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T6 3118-3122 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T7 3389-3394 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T8 3395-3405 Body_part denotes leucocytes http://purl.org/sig/ont/fma/fma62852
T9 3410-3421 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863
T10 3561-3566 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T11 3568-3590 Body_part denotes gastrointestinal tract http://purl.org/sig/ont/fma/fma71132
T12 3596-3601 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T13 3634-3641 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T14 3899-3904 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T15 3991-3996 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T16 3997-4008 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863
T17 4054-4067 Body_part denotes B lymphocytes http://purl.org/sig/ont/fma/fma62869
T18 4104-4109 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T19 4425-4433 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T20 4650-4655 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T21 4830-4838 Body_part denotes platelet http://purl.org/sig/ont/fma/fma62851
T22 4960-4967 Body_part denotes fingers http://purl.org/sig/ont/fma/fma9666
T23 4972-4976 Body_part denotes toes http://purl.org/sig/ont/fma/fma70664
T24 5013-5018 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T25 5036-5041 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T26 5046-5053 Body_part denotes kidneys http://purl.org/sig/ont/fma/fma7203
T27 5406-5411 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T28 9896-9906 Body_part denotes human body http://purl.org/sig/ont/fma/fma305853
T29 10344-10362 Body_part denotes respiratory system http://purl.org/sig/ont/fma/fma7158
T30 10453-10458 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T31 10460-10466 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 765-770 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T2 3389-3394 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T3 3596-3601 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T4 3899-3904 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T5 3991-3996 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T6 4104-4109 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T7 4650-4655 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T8 4960-4967 Body_part denotes fingers http://purl.obolibrary.org/obo/UBERON_0002389
T9 5013-5018 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T10 5036-5041 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T11 5406-5411 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T12 6206-6211 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T13 6892-6897 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T14 6958-6963 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T15 7241-7246 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T16 10344-10362 Body_part denotes respiratory system http://purl.obolibrary.org/obo/UBERON_0001004
T17 10431-10437 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T18 10453-10458 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T19 10460-10466 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113

LitCovid_AGAC

Id Subject Object Predicate Lexical cue
p58969s6 4114-4123 PosReg denotes increased

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 39-47 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T2 134-152 Disease denotes infectious disease http://purl.obolibrary.org/obo/MONDO_0005550
T3 240-248 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T4 368-376 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T5 379-388 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T6 403-405 Disease denotes he http://purl.obolibrary.org/obo/MONDO_0017319
T7 1124-1132 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T8 1182-1190 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T9 1518-1526 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T10 1636-1644 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T11 1795-1803 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T12 1823-1827 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T13 1883-1891 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T14 1975-1983 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T15 2059-2077 Disease denotes infectious disease http://purl.obolibrary.org/obo/MONDO_0005550
T16 2158-2166 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T17 2408-2416 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T18 2632-2640 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T19 2988-2996 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T20 3002-3010 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T21 3194-3203 Disease denotes diarrhoea http://purl.obolibrary.org/obo/MONDO_0001673
T22 3675-3683 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T23 3951-3959 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T24 4203-4218 Disease denotes hypercoagulable http://purl.obolibrary.org/obo/MONDO_0002305
T25 4576-4591 Disease denotes hypercoagulable http://purl.obolibrary.org/obo/MONDO_0002305
T26 5134-5149 Disease denotes hypercoagulable http://purl.obolibrary.org/obo/MONDO_0002305
T27 5184-5194 Disease denotes COVID-2019 http://purl.obolibrary.org/obo/MONDO_0100096
T28 5274-5292 Disease denotes hypercoagulability http://purl.obolibrary.org/obo/MONDO_0002305
T29 5466-5474 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T30 5568-5576 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T31 5648-5656 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T32 6676-6689 Disease denotes viral disease http://purl.obolibrary.org/obo/MONDO_0005108
T33 7391-7399 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T34 8742-8752 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T35 8767-8771 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T36 8776-8785 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T37 9233-9241 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T38 9324-9332 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T39 9575-9583 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T40 9670-9678 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T41 9920-9928 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T42 10764-10772 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T43 10883-10893 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T44 12509-12518 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T45 12715-12719 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 91-93 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T2 91-93 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T3 278-280 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T4 278-280 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T5 622-623 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T6 956-957 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T7 1546-1551 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T8 1615-1616 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T9 1654-1657 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T10 1917-1918 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T11 2338-2340 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T12 2338-2340 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T13 2426-2427 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T14 2467-2469 http://purl.obolibrary.org/obo/CLO_0050475 denotes my
T15 2742-2744 http://purl.obolibrary.org/obo/CLO_0050475 denotes my
T16 3021-3022 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T17 3066-3071 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T18 3077-3082 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T19 3343-3347 http://purl.obolibrary.org/obo/CLO_0053001 denotes 1–14
T20 3389-3394 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T21 3389-3394 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T22 3395-3405 http://purl.obolibrary.org/obo/CL_0000738 denotes leucocytes
T23 3504-3511 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T24 3561-3566 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T25 3568-3590 http://purl.obolibrary.org/obo/UBERON_0005409 denotes gastrointestinal tract
T26 3596-3601 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T27 3596-3601 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T28 3596-3601 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T29 3596-3601 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T30 3758-3763 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T31 3771-3772 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T32 3899-3904 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T33 3991-3996 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T34 3991-3996 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T35 4054-4055 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T36 4104-4109 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T37 4104-4109 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T38 4650-4655 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T39 4763-4774 http://purl.obolibrary.org/obo/PR_000007299 denotes prothrombin
T40 4853-4856 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T41 5013-5018 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T42 5036-5041 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T43 5036-5041 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T44 5036-5041 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T45 5036-5041 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T46 5046-5053 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidneys
T47 5046-5053 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidneys
T48 5046-5053 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidneys
T49 5199-5207 http://purl.obolibrary.org/obo/CLO_0001658 denotes activate
T50 5406-5411 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T51 5509-5510 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T52 5781-5786 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T53 5828-5837 http://purl.obolibrary.org/obo/OBI_0000245 denotes organized
T54 6252-6253 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T55 6422-6434 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T56 6441-6444 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T57 6510-6513 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T58 6533-6534 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T59 6643-6648 http://purl.obolibrary.org/obo/UBERON_0001456 denotes faced
T60 6657-6658 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T61 6691-6698 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T62 6832-6837 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T63 6924-6925 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T64 7294-7295 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T65 7420-7423 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T66 7763-7764 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T67 7814-7815 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T68 7947-7954 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T69 8015-8022 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T70 8172-8173 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T71 8454-8455 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T72 8486-8489 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T73 8816-8819 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T74 8827-8828 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T75 9061-9062 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T76 9353-9354 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T77 9549-9550 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T78 9896-9901 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T79 9931-9938 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T80 10012-10023 http://purl.obolibrary.org/obo/BFO_0000030 denotes objectively
T81 10263-10271 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T82 10344-10362 http://purl.obolibrary.org/obo/UBERON_0001004 denotes respiratory system
T83 10431-10437 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T84 10453-10458 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T85 10453-10458 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T86 10453-10458 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T87 10453-10458 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T88 10460-10466 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T89 10460-10466 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T90 10460-10466 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T91 10807-10808 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T92 10863-10864 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T93 10911-10912 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T94 11074-11082 http://purl.obolibrary.org/obo/CLO_0001658 denotes actively
T95 11552-11553 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 91-93 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T2 278-280 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T3 547-554 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T4 618-620 Chemical denotes Lu http://purl.obolibrary.org/obo/CHEBI_33382
T5 666-671 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T6 913-921 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T7 933-935 Chemical denotes Lu http://purl.obolibrary.org/obo/CHEBI_33382
T8 2338-2340 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T9 2909-2916 Chemical denotes heparin http://purl.obolibrary.org/obo/CHEBI_28304
T10 4781-4783 Chemical denotes PT http://purl.obolibrary.org/obo/CHEBI_141395
T11 5159-5162 Chemical denotes DIC http://purl.obolibrary.org/obo/CHEBI_4305|http://purl.obolibrary.org/obo/CHEBI_53092
T13 5505-5507 Chemical denotes Lu http://purl.obolibrary.org/obo/CHEBI_33382
T14 5553-5558 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T15 5873-5878 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T16 5889-5896 Chemical denotes Kaletra http://purl.obolibrary.org/obo/CHEBI_145924
T17 5932-5943 Chemical denotes Chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T18 5950-5959 Chemical denotes Darunavir http://purl.obolibrary.org/obo/CHEBI_367163
T19 6095-6100 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T20 6279-6290 Chemical denotes Chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T21 6699-6704 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T22 6762-6767 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T23 6866-6868 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T24 6997-6999 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T25 7482-7487 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T26 7790-7795 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T27 7888-7893 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T28 7955-7959 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T29 7980-7985 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T30 8409-8417 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T31 8438-8446 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T32 8807-8815 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T33 8977-8985 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T34 9113-9121 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T35 9441-9446 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T36 9834-9839 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T37 10809-10814 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T38 11040-11048 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T39 12298-12313 Chemical denotes glucocorticoids http://purl.obolibrary.org/obo/CHEBI_24261
T40 12358-12373 Chemical denotes glucocorticoids http://purl.obolibrary.org/obo/CHEBI_24261
T41 12535-12549 Chemical denotes corticosteroid http://purl.obolibrary.org/obo/CHEBI_50858
T42 12736-12751 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T43 12785-12800 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 446-457 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T2 4135-4146 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T3 4243-4254 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T4 4383-4392 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T5 5199-5219 http://purl.obolibrary.org/obo/GO_0050820 denotes activate coagulation
T6 5208-5219 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T7 5326-5334 http://purl.obolibrary.org/obo/GO_0050817 denotes clotting
T8 5335-5344 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T9 10472-10483 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T10 12659-12680 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-56 Sentence denotes Clinical observation and management of COVID-19 patients
T2 57-87 Sentence denotes Emerging Microbes & Infections
T3 88-90 Sentence denotes T.
T4 91-100 Sentence denotes Li et al.
T5 102-110 Sentence denotes Abstract
T6 111-119 Sentence denotes ABSTRACT
T7 120-258 Sentence denotes Three leading infectious disease experts in China were invited to share their bedside observations in the management of COVID-19 patients.
T8 259-333 Sentence denotes Professor Taisheng Li was sent to Wuhan to provide frontline medical care.
T9 334-389 Sentence denotes He depicts the clinical course of SARS-CoV-2 infection.
T10 390-598 Sentence denotes Furthermore, he observes the significant abnormality of coagulation function and proposes that the early intravenous immunoglobulin and low molecular weight heparin anticoagulation therapy are very important.
T11 599-878 Sentence denotes Professor Hongzhou Lu, a leader in China to try various anti-viral drugs, expresses concern on the quality of the ongoing clinical trials as most trials are small in scale and repetitive in nature, and emphasizes the importance of the quick publication of clinical trial results.
T12 879-1034 Sentence denotes Regarding the traditional Chinese medicine, Professor Lu suggests to develop a creative evaluation system because of the complicated chemical compositions.
T13 1035-1139 Sentence denotes Professor Wenhong Zhang is responsible for Shanghai's overall clinical management of the COVID-19 cases.
T14 1140-1200 Sentence denotes He introduces the team approach to manage COVID-19 patients.
T15 1201-1352 Sentence denotes For severe or critically ill patients, in addition to the respiratory supportive treatment, timely multiorgan evaluation and treatment is very crucial.
T16 1353-1462 Sentence denotes The medical decisions and interventions are carefully tailored to the unique characteristics of each patient.
T17 1464-1757 Sentence denotes Since late 2019 to early 2020, the sudden outbreak of COVID-19, among the general human population in the City of Wuhan, caused by the transmission of a novel coronavirus, SARS-CoV-2 [1,2], has led to over 80,000 diagnosed cases including more than 3000 deaths globally as of 29 February 2020.
T18 1758-1906 Sentence denotes While the overall mortality rate for SARS-CoV-2 seems lower than SARS or MERS, the death rate among severe cases infected by SARS-CoV-2 is alarming.
T19 1907-2005 Sentence denotes There are a wide range of efforts to develop special treatments for COVID-19 with limited success.
T20 2006-2317 Sentence denotes In the current commentary, EMI invited three leading infectious disease experts in China who have personally participated in the clinical management of COVID-19 cases to share their bedside observations and to suggest what may be important in formulating the treatment strategy to optimize the clinical outcome.
T21 2319-2443 Sentence denotes Professor Taisheng Li (being sent to Wuhan from Beijing to provide frontline care to the COVID-19 cases in a local hospital)
T22 2444-2596 Sentence denotes Since 7 February 2020, my colleagues and I went to work in the intensive care unit (ICU) of Zhongfa Xincheng Hospital, part of Tongji Hospital in Wuhan.
T23 2597-2732 Sentence denotes Although the case fatality rate of COVID-19 is not high, due to the widespread of the disease, the total number of deaths is not small.
T24 2733-2967 Sentence denotes Based on my observations in the treatment of severe and critically ill patients in the ICU, I propose that the early intravenous immunoglobulin (IVIG) and low molecular weight heparin (LMWH) anticoagulation therapy are very important.
T25 2969-2996 Sentence denotes Clinical course of COVID-19
T26 2997-3072 Sentence denotes When SARS-CoV-2 infects a person, the lesions are not limited to the lungs.
T27 3073-3242 Sentence denotes The virus causes viraemia after entering the body and the main clinical manifestations are fever, pharyngalgia, fatigue, diarrhoea and other non-specific symptoms [3,4].
T28 3243-3321 Sentence denotes This process includes the incubation phase and the early phase of the disease.
T29 3322-3377 Sentence denotes The incubation takes 1–14 days (3–7 days being common).
T30 3378-3493 Sentence denotes Peripheral blood leucocytes and lymphocytes are not significantly reduced (normal or slightly lower) at this phase.
T31 3494-3686 Sentence denotes Then, the viruses spread through the bloodstream and mainly in the lungs, gastrointestinal tract, and heart, presumably concentrated in the tissues expressing ACE2, the receptor of SARS-CoV-2.
T32 3687-3848 Sentence denotes This phase occurs around 7–14 after the onset of the symptoms when the virus starts a second attack, which is also the main cause of the aggravation of symptoms.
T33 3849-3960 Sentence denotes At this time, pulmonary lesions became worse, and chest CT scans show imaging changes consistent with COVID-19.
T34 3961-4068 Sentence denotes At this stage, the peripheral blood lymphocytes decrease significantly, involving both T and B lymphocytes.
T35 4069-4124 Sentence denotes Inflammatory factors in peripheral blood are increased.
T36 4126-4153 Sentence denotes Abnormal coagulation status
T37 4154-4283 Sentence denotes Patients at this phase will begin to develop the hypercoagulable state and D-Dimer-based coagulation factors may appear abnormal.
T38 4284-4442 Sentence denotes The use of IVIG at this time may provide patients with effective clinical benefits and inhibit the formation of inflammatory factors storm (“cytokine storm”).
T39 4443-4610 Sentence denotes LWMH therapy, suggested by colleagues at the Department of Hematology, Peking Union Medical College Hospital, may also alleviate the hypercoagulable state in patients.
T40 4611-4839 Sentence denotes During the development of dyspnoea and chest imaging changes from light to severe, the D-dimer increased from mild to significant, along with prolonged prothrombin time (PT) and gradual decrease of fibrinogen (FBG) and platelet.
T41 4840-5067 Sentence denotes Recently, it has been observed that some of the non-survivors suffered from ischaemic changes such as ecchymosis of the fingers and toes (Figure 1), at the same time as the organ functions of the heart and kidneys became worse.
T42 5068-5163 Sentence denotes The above manifestations are consistent with the diagnosis of the hypercoagulable phase of DIC.
T43 5164-5293 Sentence denotes It is believed that COVID-2019 can activate coagulation cascade through various mechanisms, leading to severe hypercoagulability.
T44 5294-5426 Sentence denotes Early anticoagulation may block clotting formation and reduce microthrombus, thereby reducing the risk of major organ damages [5,6].
T45 5427-5436 Sentence denotes Figure 1.
T46 5437-5484 Sentence denotes Ecchymosis in severe type of COVID-19 patients.
T47 5486-5583 Sentence denotes Professor Hongzhou Lu (a leader in China to try various anti-viral drugs to treat COVID-19 cases)
T48 5584-5787 Sentence denotes Considering the clinical and epidemiological characteristics of COVID-19, the possible effective medications are in dire need to improve the prognosis of the patients and to stem the spread of the virus.
T49 5788-6018 Sentence denotes More than 200 clinical trials have been organized mainly for the study of anti-viral drugs including Kaletra, Remdesivir, Arbidol, Favipiravir, Chloroquine, HCQ, Darunavir, Lianhua Qingwen Granules and Shuanghuanglian Oral Liquid.
T50 6019-6165 Sentence denotes While the clinicians are enthusiastic about exploring the efficacy of these drugs, these trials are subject to all kinds of practical limitations.
T51 6166-6237 Sentence denotes The majority of the trials are small in scale and repetitive in nature.
T52 6238-6313 Sentence denotes For instance, a dozen clinical trials on Chloroquine have been carried out.
T53 6314-6404 Sentence denotes Furthermore, due to the difference in design methodology, contradictory results may arise.
T54 6405-6532 Sentence denotes The World Health Organization (WHO) has shown deep concern over the quality of these clinical trials and has provided guidance.
T55 6533-6613 Sentence denotes A multitude of domestic experts also contributed their wisdom in different ways.
T56 6615-6630 Sentence denotes Research design
T57 6631-6800 Sentence denotes What we are faced with is a newly discovered viral disease, testing drugs are selected mainly based on the past experience of such drugs treating other related diseases.
T58 6801-6838 Sentence denotes Some of them only had in vitro tests.
T59 6839-6885 Sentence denotes Some hasn’t finished Phase II clinical trials.
T60 6886-6936 Sentence denotes Large-scale clinical trials will take a long time.
T61 6937-7151 Sentence denotes Therefore, the small-scale clinical trials, including Phase II clinical trials, are currently given priority to, in which case, its effect, proper dosage, the medication and adverse reaction are initially verified.
T62 7152-7280 Sentence denotes Those possibly effective and relatively safe medications can be coordinated to the large-scale and multi-centre clinical trials.
T63 7281-7334 Sentence denotes In this way, a bulk of repetitive trials are avoided.
T64 7335-7550 Sentence denotes Another reality situation is the fact that the National COVID-19 Treatment Guideline has been updated quite urgently to include possibly effective drugs and experts are continuously offering new medical suggestions.
T65 7551-7759 Sentence denotes Therefore, the medical workers in clinical trials usually take consideration of national guideline and expert opinion, while carrying out the trial under the premise that the normal treatment is not affected.
T66 7760-7850 Sentence denotes As a result, the intervention group may be covered by a variety of anti-viral medications.
T67 7851-7986 Sentence denotes It is difficult to leave the control group blank in order to confirm the absolute effect of the testing drug in the intervention group.
T68 7987-8053 Sentence denotes The specific effects of the testing medication cannot be verified.
T69 8054-8242 Sentence denotes In this case, the current clinical studies are not as rigorous as the traditional clinical trials, but they help draw a quick initial result which can help with the following study design.
T70 8243-8387 Sentence denotes It is of vital importance to motivate the quick publication of clinical trial results, which can contribute significantly to clinical treatment.
T71 8389-8417 Sentence denotes Traditional Chinese medicine
T72 8418-8529 Sentence denotes Traditional Chinese medicine, after a long history of clinical use, has carved out its own theory and practice.
T73 8530-8846 Sentence denotes The most typical ones are the “Doctrine of Shanghai” (febrile diseases caused by exogenous pathogenic factors) and the “Doctrine of Seasonal Febrile Diseases.” In the diagnosis and treatment of acute respiratory infectious diseases like SARS and influenza, traditional Chinese medicine has played a significant role.
T74 8847-8964 Sentence denotes But its treatment determination is based on “Syndrome Differentiation,” in which case, individual plans are produced.
T75 8965-9044 Sentence denotes The Chinese medicine formulae are typical of complicated chemical compositions.
T76 9045-9144 Sentence denotes This means that a creative evaluation system of traditional Chinese medicine needs to be developed.
T77 9146-9248 Sentence denotes Professor Wenhong Zhang (responsible for Shanghai’s overall clinical management of the COVID-19 cases)
T78 9249-9547 Sentence denotes Since late January, I have been working to ensure the high-quality care of COVID-19 patient by building a highly experienced clinician team, Shanghai Clinical Treatment Expert Group, based on group members’ clinical and scientific expertise to provide the advice to complicated clinical management.
T79 9549-9592 Sentence denotes A team approach to manage COVID-19 patients
T80 9593-9695 Sentence denotes Currently, there have been more than 330 laboratory-confirmed adult cases of COVID-19 in Shanghai [7].
T81 9696-9813 Sentence denotes Most patients (>90%) are in mild or moderate states, and more than 90% of them have been cured and discharged by now.
T82 9814-10151 Sentence denotes Because no specific drugs have been shown with clear effectiveness in helping the human body to clear the SARS-CoV-2 viruses, the disease severity rate in Shanghai (26 cases, around 9–10%) actually objectively reflected the natural history of the disease, and was comparable with the severity rate at other places outside Hubei Province.
T83 10152-10291 Sentence denotes All critically ill patients received invasive mechanical ventilation, and six patients received extracorporeal membrane oxygenation (ECMO).
T84 10292-10519 Sentence denotes We found that in addition to the involvement of the respiratory system, critically ill patients often had systemic involvement of multiple organs, including the heart, kidney, and coagulation system in the early disease course.
T85 10520-10618 Sentence denotes Sometimes multiple system involvement was observed even at the time of initial hospital admission.
T86 10619-10742 Sentence denotes Therefore, in addition to the respiratory supportive treatment, timely multiorgan evaluation and treatment is very crucial.
T87 10743-10975 Sentence denotes Every critically ill COVID-19 patient in Shanghai is managed by a group of healthcare providers which includes at least a pulmonologist, an infectious diseases expert, a critical care specialist, and an ECMO specialist if necessary.
T88 10976-11130 Sentence denotes Nephrologists, psychiatrists, physicians of traditional Chinese medicine, experienced nurses also actively participate in managing these patients as well.
T89 11131-11198 Sentence denotes Besides, substantial heterogeneity among severe patients was noted.
T90 11199-11279 Sentence denotes Mild patients are more alike, but each severe case is severe in his/her own way.
T91 11280-11365 Sentence denotes There may be multiple pathophysiological mechanisms in these critically ill patients.
T92 11366-11577 Sentence denotes The types of critically ill patients need to be more carefully classified in order to perform more individualized treatment, in addition to conducting more dedicated research to develop a unique management plan.
T93 11578-11703 Sentence denotes In Shanghai, medical decisions and interventions are carefully tailored to the unique characteristics of each severe patient.
T94 11705-11760 Sentence denotes Early and effective treatment of mild cases is critical
T95 11761-11814 Sentence denotes The overall mortality rate is about 0.9% in Shanghai.
T96 11815-12007 Sentence denotes However, we have found that once the disease course progressed to the critical illness state (requiring mechanical ventilation), the prognosis of the patients would become significantly worse.
T97 12008-12192 Sentence denotes From this perspective, treatments that can prevent mild state from progressing to the severe or critical state will significantly improve the overall prognosis of the clinical courses.
T98 12193-12346 Sentence denotes Such effective treatments include intermittent short-term haemofiltration (ISVVH), low-dose short-course glucocorticoids therapy, among other approaches.
T99 12347-12439 Sentence denotes The use of glucocorticoids is rather controversial and there is no general agreement by now.
T100 12440-12616 Sentence denotes Based on our experiences, stably mild patients could self-manage the infection effectively and corticosteroid would not be recommended for them considering its potential risks.
T101 12617-12769 Sentence denotes For patients who have an overly exuberant inflammatory response or are at high risk of developing ARDS, early-start of corticosteroids could be helpful.
T102 12770-12838 Sentence denotes The benefit of corticosteroids as rescue treatment remains doubtful.
T103 12840-12860 Sentence denotes Disclosure statement
T104 12861-12925 Sentence denotes No potential conflict of interest was reported by the author(s).

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 431-457 Phenotype denotes abnormality of coagulation http://purl.obolibrary.org/obo/HP_0001928
T2 3164-3169 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T3 3171-3183 Phenotype denotes pharyngalgia http://purl.obolibrary.org/obo/HP_0033050
T4 3185-3192 Phenotype denotes fatigue http://purl.obolibrary.org/obo/HP_0012378
T5 3194-3203 Phenotype denotes diarrhoea http://purl.obolibrary.org/obo/HP_0002014
T6 4126-4146 Phenotype denotes Abnormal coagulation http://purl.obolibrary.org/obo/HP_0001928
T7 4425-4439 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T8 4637-4645 Phenotype denotes dyspnoea http://purl.obolibrary.org/obo/HP_0002094
T9 4753-4779 Phenotype denotes prolonged prothrombin time http://purl.obolibrary.org/obo/HP_0008151
T10 4781-4783 Phenotype denotes PT http://purl.obolibrary.org/obo/HP_0008151
T11 4942-4952 Phenotype denotes ecchymosis http://purl.obolibrary.org/obo/HP_0031364
T12 5274-5292 Phenotype denotes hypercoagulability http://purl.obolibrary.org/obo/HP_0100724
T13 5437-5447 Phenotype denotes Ecchymosis http://purl.obolibrary.org/obo/HP_0031364

MyTest

Id Subject Object Predicate Lexical cue
32208840-32174267-27774823 9692-9693 32174267 denotes 7

2_test

Id Subject Object Predicate Lexical cue
32208840-32174267-27774823 9692-9693 32174267 denotes 7

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1 39-47 Disease denotes COVID-19 MESH:C000657245
14 249-257 Species denotes patients Tax:9606
15 1191-1199 Species denotes patients Tax:9606
16 1230-1238 Species denotes patients Tax:9606
17 1454-1461 Species denotes patient Tax:9606
18 526-554 Chemical denotes low molecular weight heparin MESH:D006495
19 134-152 Disease denotes infectious disease MESH:D003141
20 240-248 Disease denotes COVID-19 MESH:C000657245
21 368-388 Disease denotes SARS-CoV-2 infection MESH:C000657245
22 431-466 Disease denotes abnormality of coagulation function MESH:D025861
23 1124-1132 Disease denotes COVID-19 MESH:C000657245
24 1182-1190 Disease denotes COVID-19 MESH:C000657245
25 1215-1229 Disease denotes critically ill MESH:D016638
40 1546-1551 Species denotes human Tax:9606
41 1617-1634 Species denotes novel coronavirus Tax:2697049
42 1636-1646 Species denotes SARS-CoV-2 Tax:2697049
43 1795-1805 Species denotes SARS-CoV-2 Tax:2697049
44 1883-1893 Species denotes SARS-CoV-2 Tax:2697049
45 1518-1526 Disease denotes COVID-19 MESH:C000657245
46 1718-1724 Disease denotes deaths MESH:D003643
47 1776-1785 Disease denotes mortality MESH:D003643
48 1831-1835 Disease denotes MERS MESH:D018352
49 1841-1846 Disease denotes death MESH:D003643
50 1871-1879 Disease denotes infected MESH:D007239
51 1975-1983 Disease denotes COVID-19 MESH:C000657245
52 2059-2077 Disease denotes infectious disease MESH:D003141
53 2158-2166 Disease denotes COVID-19 MESH:C000657245
55 2408-2416 Disease denotes COVID-19 MESH:C000657245
62 2804-2812 Species denotes patients Tax:9606
63 2888-2916 Chemical denotes low molecular weight heparin MESH:D006495
64 2918-2922 Chemical denotes LMWH MESH:D006495
65 2632-2640 Disease denotes COVID-19 MESH:C000657245
66 2712-2718 Disease denotes deaths MESH:D003643
67 2789-2803 Disease denotes critically ill MESH:D016638
69 2988-2996 Disease denotes COVID-19 MESH:C000657245
80 3653-3657 Gene denotes ACE2 Gene:59272
81 3002-3012 Species denotes SARS-CoV-2 Tax:2697049
82 3675-3685 Species denotes SARS-CoV-2 Tax:2697049
83 3090-3098 Disease denotes viraemia
84 3164-3169 Disease denotes fever MESH:D005334
85 3171-3183 Disease denotes pharyngalgia MESH:D010608
86 3185-3192 Disease denotes fatigue MESH:D005221
87 3194-3203 Disease denotes diarrhoea MESH:D003967
88 3863-3880 Disease denotes pulmonary lesions MESH:D008171
89 3951-3959 Disease denotes COVID-19 MESH:C000657245
91 4126-4153 Disease denotes Abnormal coagulation status MESH:D025861
94 5475-5483 Species denotes patients Tax:9606
95 5466-5474 Disease denotes COVID-19 MESH:C000657245
105 4809-4819 Gene denotes fibrinogen Gene:2244
106 4154-4162 Species denotes Patients Tax:9606
107 4325-4333 Species denotes patients Tax:9606
108 4601-4609 Species denotes patients Tax:9606
109 4443-4447 Chemical denotes LWMH
110 4637-4645 Disease denotes dyspnoea MESH:D004417
111 5159-5162 Disease denotes DIC MESH:D004211
112 5184-5194 Disease denotes COVID-2019 MESH:C000657245
113 5274-5292 Disease denotes hypercoagulability MESH:D019851
115 5568-5576 Disease denotes COVID-19 MESH:C000657245
127 5742-5750 Species denotes patients Tax:9606
128 5889-5896 Chemical denotes Kaletra MESH:C558899
129 5898-5908 Chemical denotes Remdesivir MESH:C000606551
130 5910-5917 Chemical denotes Arbidol MESH:C086979
131 5919-5930 Chemical denotes Favipiravir MESH:C462182
132 5932-5943 Chemical denotes Chloroquine MESH:D002738
133 5945-5948 Chemical denotes HCQ MESH:D006886
134 5950-5959 Chemical denotes Darunavir MESH:D000069454
135 6279-6290 Chemical denotes Chloroquine MESH:D002738
136 5648-5656 Disease denotes COVID-19 MESH:C000657245
137 6044-6056 Disease denotes enthusiastic
139 6676-6689 Disease denotes viral disease MESH:D001102
141 7391-7399 Disease denotes COVID-19 MESH:C000657245
144 8662-8687 Disease denotes Seasonal Febrile Diseases MESH:D016574
145 8730-8761 Disease denotes respiratory infectious diseases MESH:D012141
147 9233-9241 Disease denotes COVID-19 MESH:C000657245
150 9333-9340 Species denotes patient Tax:9606
151 9324-9332 Disease denotes COVID-19 MESH:C000657245
153 9575-9583 Disease denotes COVID-19 MESH:C000657245
164 9989-10000 Gene denotes around 9–10
165 9701-9709 Species denotes patients Tax:9606
166 9896-9901 Species denotes human Tax:9606
167 9920-9930 Species denotes SARS-CoV-2 Tax:2697049
168 10171-10179 Species denotes patients Tax:9606
169 10230-10238 Species denotes patients Tax:9606
170 10379-10387 Species denotes patients Tax:9606
171 9670-9678 Disease denotes COVID-19 MESH:C000657245
172 10156-10170 Disease denotes critically ill MESH:D016638
173 10364-10378 Disease denotes critically ill MESH:D016638
186 10773-10780 Species denotes patient Tax:9606
187 11113-11121 Species denotes patients Tax:9606
188 11179-11187 Species denotes patients Tax:9606
189 11204-11212 Species denotes patients Tax:9606
190 11356-11364 Species denotes patients Tax:9606
191 11394-11402 Species denotes patients Tax:9606
192 11695-11702 Species denotes patient Tax:9606
193 10749-10763 Disease denotes critically ill MESH:D016638
194 10764-10772 Disease denotes COVID-19 MESH:C000657245
195 10883-10902 Disease denotes infectious diseases MESH:D003141
196 11341-11355 Disease denotes critically ill MESH:D016638
197 11379-11393 Disease denotes critically ill MESH:D016638
204 11965-11973 Species denotes patients Tax:9606
205 12478-12486 Species denotes patients Tax:9606
206 12621-12629 Species denotes patients Tax:9606
207 11773-11782 Disease denotes mortality MESH:D003643
208 12509-12518 Disease denotes infection MESH:D007239
209 12715-12719 Disease denotes ARDS MESH:D012128