PMC:7102662 / 8731-10949
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T26 | 1877-1882 | Body_part | denotes | heart | http://purl.org/sig/ont/fma/fma7088 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T13 | 1877-1882 | Body_part | denotes | heart | http://purl.obolibrary.org/obo/UBERON_0000948 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T90 | 128-136 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T91 | 356-365 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T92 | 448-456 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T93 | 502-510 | Disease | denotes | diabetes | http://purl.obolibrary.org/obo/MONDO_0005015 |
| T94 | 519-542 | Disease | denotes | cerebrovascular disease | http://purl.obolibrary.org/obo/MONDO_0011057 |
| T95 | 547-559 | Disease | denotes | hypertension | http://purl.obolibrary.org/obo/MONDO_0005044 |
| T96 | 605-613 | Disease | denotes | diabetes | http://purl.obolibrary.org/obo/MONDO_0005015 |
| T97 | 618-630 | Disease | denotes | hypertension | http://purl.obolibrary.org/obo/MONDO_0005044 |
| T98 | 718-741 | Disease | denotes | cerebrovascular disease | http://purl.obolibrary.org/obo/MONDO_0011057 |
| T99 | 801-809 | Disease | denotes | diabetes | http://purl.obolibrary.org/obo/MONDO_0005015 |
| T100 | 818-841 | Disease | denotes | cerebrovascular disease | http://purl.obolibrary.org/obo/MONDO_0011057 |
| T101 | 846-858 | Disease | denotes | hypertension | http://purl.obolibrary.org/obo/MONDO_0005044 |
| T102 | 1177-1185 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T103 | 1334-1346 | Disease | denotes | hypertension | http://purl.obolibrary.org/obo/MONDO_0005044 |
| T104 | 1348-1356 | Disease | denotes | diabetes | http://purl.obolibrary.org/obo/MONDO_0005015 |
| T105 | 1836-1844 | Disease | denotes | diabetes | http://purl.obolibrary.org/obo/MONDO_0005015 |
| T106 | 1866-1890 | Disease | denotes | congestive heart failure | http://purl.obolibrary.org/obo/MONDO_0005009 |
| T107 | 1877-1890 | Disease | denotes | heart failure | http://purl.obolibrary.org/obo/MONDO_0005252 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T55 | 367-368 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T56 | 879-882 | http://purl.obolibrary.org/obo/CLO_0001562 | denotes | a 2 |
| T57 | 879-882 | http://purl.obolibrary.org/obo/CLO_0001563 | denotes | a 2 |
| T58 | 1041-1042 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T59 | 1662-1667 | http://purl.obolibrary.org/obo/CLO_0001236 | denotes | 2]. A |
| T60 | 1755-1756 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T61 | 1877-1882 | http://purl.obolibrary.org/obo/UBERON_0000948 | denotes | heart |
| T62 | 1877-1882 | http://purl.obolibrary.org/obo/UBERON_0007100 | denotes | heart |
| T63 | 1877-1882 | http://purl.obolibrary.org/obo/UBERON_0015228 | denotes | heart |
| T64 | 1877-1882 | http://www.ebi.ac.uk/efo/EFO_0000815 | denotes | heart |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T27 | 547-559 | Phenotype | denotes | hypertension | http://purl.obolibrary.org/obo/HP_0000822 |
| T28 | 618-630 | Phenotype | denotes | hypertension | http://purl.obolibrary.org/obo/HP_0000822 |
| T29 | 846-858 | Phenotype | denotes | hypertension | http://purl.obolibrary.org/obo/HP_0000822 |
| T30 | 1334-1346 | Phenotype | denotes | hypertension | http://purl.obolibrary.org/obo/HP_0000822 |
| T31 | 1866-1890 | Phenotype | denotes | congestive heart failure | http://purl.obolibrary.org/obo/HP_0001635 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T78 | 0-41 | Sentence | denotes | 2.1.1 Role of underling CV comorbidities |
| T79 | 42-213 | Sentence | denotes | The patients with pre-existing CVD appear to have heightened vulnerability to develop COVID-19 and tend to have more severe disease with worse clinical outcomes [1,4,6,8]. |
| T80 | 214-366 | Sentence | denotes | Various CV risk factors also adversely affect porgnosis of these patients, although they do not seem to increase likleihood of developing the infection. |
| T81 | 367-577 | Sentence | denotes | A meta-analysis of six published studies from China including 1527 patients with COVID-19 reported 9.7%, 16.4% and 17.1% prevalence of diabetes, cardio-cerebrovascular disease and hypertension respectively [4]. |
| T82 | 578-766 | Sentence | denotes | Although the prevalence of diabetes and hypertension in this cohort was same as in the Chinese general population, the prevalence of cardio-cerebrovascular disease was considerably higher. |
| T83 | 767-1040 | Sentence | denotes | More importantly, the presence of diabetes, cardio-cerebrovascular disease and hypertension was associated with a 2-fold, 3-fold and 2-fold greater risk of severe disease or requiring intensive care unit (ICU) admission, suggesting prognostic impact of these comorbidities. |
| T84 | 1041-1190 | Sentence | denotes | A much larger report from the Chinese Center for Disease Control and Prevention described clinical outcomes in 44672 confirmed cases of COVID-19 [1]. |
| T85 | 1191-1365 | Sentence | denotes | The overall case fatality rate (CFR) was 2.3% in the entire cohort but significantly higher (6%, 7.3% and 10.5% respectively) in patients with hypertension, diabetes and CVD. |
| T86 | 1366-1537 | Sentence | denotes | Although data is lacking, the prevalence of various CV comorbidities and their impact on clinical outcomes seem to vary considerably across different geographic locations. |
| T87 | 1538-1665 | Sentence | denotes | The CFRs have been lower in China outside Hubei province and many other countries but much higher in some European nations [2]. |
| T88 | 1666-1788 | Sentence | denotes | A small report including 21 patients from Washington, United States of America presented a particularly grim scenario [9]. |
| T89 | 1789-1900 | Sentence | denotes | Comorbidities were common in this cohort, with diabetes present in 33.3% and congestive heart failure in 42.9%. |
| T90 | 1901-1978 | Sentence | denotes | Acute cardiac dysfunction occurred in 33.3% patients and 52.4% patients died. |
| T91 | 1979-2218 | Sentence | denotes | However, the overall CFR in the United States seems to be much lower (201 deaths out of 15219 confirmed cases) [2], although it is likely to rise as many of the patients are currently hospitalized and have not yet had the definite outcome. |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T198 | 128-136 | SP_7 | denotes | COVID-19 |
| T199 | 448-456 | SP_7 | denotes | COVID-19 |
| T200 | 519-534 | UBERON:0002037 | denotes | cerebrovascular |
| T201 | 718-733 | UBERON:0002037 | denotes | cerebrovascular |
| T202 | 818-833 | UBERON:0002037 | denotes | cerebrovascular |
| T203 | 961-965 | CL:0000037 | denotes | care |
| T204 | 1177-1185 | SP_7 | denotes | COVID-19 |
| T205 | 1877-1882 | UBERON:0000948 | denotes | heart |
| T206 | 1907-1914 | UBERON:0000948 | denotes | cardiac |
| T207 | 1973-1977 | GO:0016265 | denotes | died |
| T208 | 2053-2059 | GO:0016265 | denotes | deaths |
| T96699 | 4-9 | SP_9 | denotes | 1 Ro |
| T94696 | 60-71 | SP_7 | denotes | pre-existin |
| T73378 | 109-120 | NCBITaxon:11118 | denotes | ability to |
| T49479 | 128-135 | NCBITaxon:species | denotes | COVID-1 |
| T49662 | 147-160 | NCBITaxon:11118 | denotes | o have more s |
| T91764 | 180-185 | SP_6;NCBITaxon:9606 | denotes | orse |
| T16144 | 311-315 | SP_10 | denotes | eem |
| T61914 | 317-321 | SP_9 | denotes | inc |
| T67143 | 338-346 | SP_7 | denotes | of devel |
| T79419 | 359-377 | UBERON:0000065 | denotes | ection. A meta-ana |
| T22287 | 404-416 | SP_7 | denotes | ies from Chi |
| T48200 | 544-552 | SP_7 | denotes | nd hyper |
| T78437 | 569-579 | UBERON:0002349 | denotes | ely [4]. A |
| T61571 | 588-598 | SP_7 | denotes | he prevale |
| T36103 | 606-611 | SP_6;NCBITaxon:9606 | denotes | iabet |
| T42181 | 632-663 | PG_10;PR:000003622 | denotes | n this cohort was same as in th |
| T13911 | 665-671 | G_3;PG_10;PR:000003622 | denotes | Chines |
| T79903 | 676-684 | GO:0016020 | denotes | eral pop |
| T50101 | 722-731 | GO:0010467 | denotes | brovascul |
| T80107 | 735-740 | UBERON:0000948 | denotes | iseas |
| T55772 | 745-750 | UBERON:0000170 | denotes | cons |
| T53520 | 752-756 | G_3;PG_10;PR:000003622 | denotes | erab |
| T48624 | 797-807 | GO:0065007 | denotes | of diabet |
| T21124 | 811-813 | UBERON:0001017 | denotes | ca |
| T78086 | 895-905 | SP_7 | denotes | and 2-fol |
| T54232 | 909-913 | G_3;PG_10;PR:000003622 | denotes | eate |
| T64983 | 942-946 | G_3;PG_10;PR:000003622 | denotes | equi |
| T4317 | 984-994 | UBERON:0002349 | denotes | on, sugges |
| T54741 | 999-1003 | UBERON:0002048 | denotes | prog |
| T139 | 1065-1075 | SP_7 | denotes | m the Chin |
| T140 | 1192-1198 | UBERON:0000062 | denotes | he ove |
| T141 | 1210-1219 | UBERON:0000062 | denotes | tality ra |
| T142 | 1334-1342 | SP_7 | denotes | hyperten |
| T143 | 1360-1370 | UBERON:0002349 | denotes | CVD. Alth |
| T144 | 1498-1508 | UBERON:0001004 | denotes | across di |
| T145 | 1530-1540 | UBERON:0002349 | denotes | ations. Th |
| T146 | 1595-1605 | UBERON:0002349 | denotes | and many o |
| T147 | 1636-1644 | UBERON:0005985 | denotes | in some |
| T148 | 1645-1655 | GO:0007596 | denotes | uropean na |
| T149 | 1730-1738 | UBERON:0005985 | denotes | tes of A |
| T150 | 1739-1744 | UBERON:0000178 | denotes | erica |
| T151 | 1799-1809 | UBERON:0002349 | denotes | ies were c |
| T152 | 1822-1835 | GO:0007596 | denotes | cohort, with |
| T153 | 1961-1966 | CHEBI:36044;CHEBI:36044 | denotes | 4% pa |
| T154 | 1968-1983 | CHEBI:50858;CHEBI:50858 | denotes | ents died. Howe |
| T155 | 2021-2029 | SP_7 | denotes | tes seem |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32247212-31986264-25241179 | 208-209 | 31986264 | denotes | 6 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 293 | 46-54 | Species | denotes | patients | Tax:9606 |
| 294 | 279-287 | Species | denotes | patients | Tax:9606 |
| 295 | 434-442 | Species | denotes | patients | Tax:9606 |
| 296 | 1320-1328 | Species | denotes | patients | Tax:9606 |
| 297 | 73-76 | Disease | denotes | CVD | MESH:D002318 |
| 298 | 128-136 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 299 | 356-365 | Disease | denotes | infection | MESH:D007239 |
| 300 | 448-456 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 301 | 502-510 | Disease | denotes | diabetes | MESH:D003920 |
| 302 | 512-542 | Disease | denotes | cardio-cerebrovascular disease | MESH:D002561 |
| 303 | 547-559 | Disease | denotes | hypertension | MESH:D006973 |
| 304 | 605-613 | Disease | denotes | diabetes | MESH:D003920 |
| 305 | 618-630 | Disease | denotes | hypertension | MESH:D006973 |
| 306 | 711-741 | Disease | denotes | cardio-cerebrovascular disease | MESH:D002561 |
| 307 | 801-809 | Disease | denotes | diabetes | MESH:D003920 |
| 308 | 811-841 | Disease | denotes | cardio-cerebrovascular disease | MESH:D002561 |
| 309 | 846-858 | Disease | denotes | hypertension | MESH:D006973 |
| 310 | 1177-1185 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 311 | 1334-1346 | Disease | denotes | hypertension | MESH:D006973 |
| 312 | 1348-1356 | Disease | denotes | diabetes | MESH:D003920 |
| 313 | 1361-1364 | Disease | denotes | CVD | MESH:D002318 |
| 323 | 1694-1702 | Species | denotes | patients | Tax:9606 |
| 324 | 1945-1953 | Species | denotes | patients | Tax:9606 |
| 325 | 1964-1972 | Species | denotes | patients | Tax:9606 |
| 326 | 2140-2148 | Species | denotes | patients | Tax:9606 |
| 327 | 1836-1844 | Disease | denotes | diabetes | MESH:D003920 |
| 328 | 1866-1890 | Disease | denotes | congestive heart failure | MESH:D006333 |
| 329 | 1907-1926 | Disease | denotes | cardiac dysfunction | MESH:D006331 |
| 330 | 1973-1977 | Disease | denotes | died | MESH:D003643 |
| 331 | 2053-2059 | Disease | denotes | deaths | MESH:D003643 |