PMC:7102662 / 488-1256 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T1","span":{"begin":180,"end":189},"obj":"Body_part"},{"id":"T2","span":{"begin":357,"end":371},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"fma_id","subj":"T1","obj":"http://purl.org/sig/ont/fma/fma62338"},{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma14067"}],"text":"Respiratory illness is the dominant clinical manifestation of COVID-19; CV involvement occurs much less commonly. Acute cardiac injury, defined as significant elevation of cardiac troponins, is the most commonly reported cardiac abnormality in COVID-19. It occurs in approximately 8–12% of all patients. Direct myocardial injury due to viral involvement of cardiomyocytes and the effect of systemic inflammation appear to be the most common mechanisms responsible for cardiac injury. The information about other CV manifestations in COVID-19 is very limited at present. Nonetheless, it has been consistently shown that the presence of pre-existing CV disease and/or development of acute cardiac injury are associated with significantly worse outcome in these patients."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T7","span":{"begin":62,"end":70},"obj":"Disease"},{"id":"T8","span":{"begin":128,"end":134},"obj":"Disease"},{"id":"T9","span":{"begin":244,"end":252},"obj":"Disease"},{"id":"T10","span":{"begin":322,"end":328},"obj":"Disease"},{"id":"T11","span":{"begin":399,"end":411},"obj":"Disease"},{"id":"T12","span":{"begin":476,"end":482},"obj":"Disease"},{"id":"T13","span":{"begin":533,"end":541},"obj":"Disease"},{"id":"T14","span":{"begin":695,"end":701},"obj":"Disease"}],"attributes":[{"id":"A7","pred":"mondo_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A8","pred":"mondo_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/MONDO_0021178"},{"id":"A9","pred":"mondo_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A10","pred":"mondo_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/MONDO_0021178"},{"id":"A11","pred":"mondo_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"},{"id":"A12","pred":"mondo_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/MONDO_0021178"},{"id":"A13","pred":"mondo_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A14","pred":"mondo_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/MONDO_0021178"}],"text":"Respiratory illness is the dominant clinical manifestation of COVID-19; CV involvement occurs much less commonly. Acute cardiac injury, defined as significant elevation of cardiac troponins, is the most commonly reported cardiac abnormality in COVID-19. It occurs in approximately 8–12% of all patients. Direct myocardial injury due to viral involvement of cardiomyocytes and the effect of systemic inflammation appear to be the most common mechanisms responsible for cardiac injury. The information about other CV manifestations in COVID-19 is very limited at present. Nonetheless, it has been consistently shown that the presence of pre-existing CV disease and/or development of acute cardiac injury are associated with significantly worse outcome in these patients."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T3","span":{"begin":357,"end":371},"obj":"http://purl.obolibrary.org/obo/CL_0000746"},{"id":"T4","span":{"begin":586,"end":589},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"}],"text":"Respiratory illness is the dominant clinical manifestation of COVID-19; CV involvement occurs much less commonly. Acute cardiac injury, defined as significant elevation of cardiac troponins, is the most commonly reported cardiac abnormality in COVID-19. It occurs in approximately 8–12% of all patients. Direct myocardial injury due to viral involvement of cardiomyocytes and the effect of systemic inflammation appear to be the most common mechanisms responsible for cardiac injury. The information about other CV manifestations in COVID-19 is very limited at present. Nonetheless, it has been consistently shown that the presence of pre-existing CV disease and/or development of acute cardiac injury are associated with significantly worse outcome in these patients."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T2","span":{"begin":0,"end":19},"obj":"Phenotype"},{"id":"T3","span":{"begin":221,"end":240},"obj":"Phenotype"}],"attributes":[{"id":"A2","pred":"hp_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/HP_0002086"},{"id":"A3","pred":"hp_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/HP_0001627"}],"text":"Respiratory illness is the dominant clinical manifestation of COVID-19; CV involvement occurs much less commonly. Acute cardiac injury, defined as significant elevation of cardiac troponins, is the most commonly reported cardiac abnormality in COVID-19. It occurs in approximately 8–12% of all patients. Direct myocardial injury due to viral involvement of cardiomyocytes and the effect of systemic inflammation appear to be the most common mechanisms responsible for cardiac injury. The information about other CV manifestations in COVID-19 is very limited at present. Nonetheless, it has been consistently shown that the presence of pre-existing CV disease and/or development of acute cardiac injury are associated with significantly worse outcome in these patients."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T1","span":{"begin":399,"end":411},"obj":"http://purl.obolibrary.org/obo/GO_0006954"}],"text":"Respiratory illness is the dominant clinical manifestation of COVID-19; CV involvement occurs much less commonly. Acute cardiac injury, defined as significant elevation of cardiac troponins, is the most commonly reported cardiac abnormality in COVID-19. It occurs in approximately 8–12% of all patients. Direct myocardial injury due to viral involvement of cardiomyocytes and the effect of systemic inflammation appear to be the most common mechanisms responsible for cardiac injury. The information about other CV manifestations in COVID-19 is very limited at present. Nonetheless, it has been consistently shown that the presence of pre-existing CV disease and/or development of acute cardiac injury are associated with significantly worse outcome in these patients."}

{"project":"LitCovid-sentences","denotations":[{"id":"T9","span":{"begin":0,"end":113},"obj":"Sentence"},{"id":"T10","span":{"begin":114,"end":253},"obj":"Sentence"},{"id":"T11","span":{"begin":254,"end":303},"obj":"Sentence"},{"id":"T12","span":{"begin":304,"end":483},"obj":"Sentence"},{"id":"T13","span":{"begin":484,"end":569},"obj":"Sentence"},{"id":"T14","span":{"begin":570,"end":768},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Respiratory illness is the dominant clinical manifestation of COVID-19; CV involvement occurs much less commonly. Acute cardiac injury, defined as significant elevation of cardiac troponins, is the most commonly reported cardiac abnormality in COVID-19. It occurs in approximately 8–12% of all patients. Direct myocardial injury due to viral involvement of cardiomyocytes and the effect of systemic inflammation appear to be the most common mechanisms responsible for cardiac injury. The information about other CV manifestations in COVID-19 is very limited at present. Nonetheless, it has been consistently shown that the presence of pre-existing CV disease and/or development of acute cardiac injury are associated with significantly worse outcome in these patients."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T8","span":{"begin":62,"end":70},"obj":"SP_7"},{"id":"T9","span":{"begin":120,"end":127},"obj":"UBERON:0000948"},{"id":"T10","span":{"begin":172,"end":179},"obj":"UBERON:0000948"},{"id":"T11","span":{"begin":221,"end":228},"obj":"UBERON:0000948"},{"id":"T12","span":{"begin":244,"end":252},"obj":"SP_7"},{"id":"T13","span":{"begin":311,"end":321},"obj":"UBERON:0002349"},{"id":"T14","span":{"begin":336,"end":341},"obj":"NCBITaxon:10239"},{"id":"T15","span":{"begin":357,"end":371},"obj":"CL:0000746"},{"id":"T16","span":{"begin":468,"end":475},"obj":"UBERON:0000948"},{"id":"T17","span":{"begin":533,"end":541},"obj":"SP_7"},{"id":"T18","span":{"begin":687,"end":694},"obj":"UBERON:0000948"},{"id":"T87279","span":{"begin":62,"end":70},"obj":"SP_7"},{"id":"T87773","span":{"begin":120,"end":127},"obj":"UBERON:0000948"},{"id":"T7216","span":{"begin":172,"end":179},"obj":"UBERON:0000948"},{"id":"T99296","span":{"begin":221,"end":228},"obj":"UBERON:0000948"},{"id":"T67128","span":{"begin":244,"end":252},"obj":"SP_7"},{"id":"T41684","span":{"begin":311,"end":321},"obj":"UBERON:0002349"},{"id":"T17482","span":{"begin":336,"end":341},"obj":"NCBITaxon:10239"},{"id":"T74925","span":{"begin":357,"end":371},"obj":"CL:0000746"},{"id":"T44150","span":{"begin":468,"end":475},"obj":"UBERON:0000948"},{"id":"T44250","span":{"begin":533,"end":541},"obj":"SP_7"},{"id":"T51214","span":{"begin":687,"end":694},"obj":"UBERON:0000948"}],"text":"Respiratory illness is the dominant clinical manifestation of COVID-19; CV involvement occurs much less commonly. Acute cardiac injury, defined as significant elevation of cardiac troponins, is the most commonly reported cardiac abnormality in COVID-19. It occurs in approximately 8–12% of all patients. Direct myocardial injury due to viral involvement of cardiomyocytes and the effect of systemic inflammation appear to be the most common mechanisms responsible for cardiac injury. The information about other CV manifestations in COVID-19 is very limited at present. Nonetheless, it has been consistently shown that the presence of pre-existing CV disease and/or development of acute cardiac injury are associated with significantly worse outcome in these patients."}

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