PMC:7102662 / 2920-4809
Annnotations
LitCovid_Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1601-1608 | https://glytoucan.org/Structures/Glycans/G15021LG | denotes | glucose |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T3 | 167-177 | Body_part | denotes | troponin I | http://purl.org/sig/ont/fma/fma62340 |
| T4 | 167-175 | Body_part | denotes | troponin | http://purl.org/sig/ont/fma/fma62338 |
| T5 | 674-689 | Body_part | denotes | coronary artery | http://purl.org/sig/ont/fma/fma49893 |
| T6 | 865-870 | Body_part | denotes | Heart | http://purl.org/sig/ont/fma/fma7088 |
| T7 | 1056-1061 | Body_part | denotes | heart | http://purl.org/sig/ont/fma/fma7088 |
| T8 | 1175-1180 | Body_part | denotes | heart | http://purl.org/sig/ont/fma/fma7088 |
| T9 | 1591-1596 | Body_part | denotes | lipid | http://purl.org/sig/ont/fma/fma67264 |
| T10 | 1601-1608 | Body_part | denotes | glucose | http://purl.org/sig/ont/fma/fma82743 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 674-689 | Body_part | denotes | coronary artery | http://purl.obolibrary.org/obo/UBERON_0001621 |
| T2 | 683-689 | Body_part | denotes | artery | http://purl.obolibrary.org/obo/UBERON_0001637 |
| T3 | 865-870 | Body_part | denotes | Heart | http://purl.obolibrary.org/obo/UBERON_0000948 |
| T4 | 1056-1061 | Body_part | denotes | heart | http://purl.obolibrary.org/obo/UBERON_0000948 |
| T5 | 1175-1180 | Body_part | denotes | heart | http://purl.obolibrary.org/obo/UBERON_0000948 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T27 | 40-64 | Disease | denotes | coronavirus disease 2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T28 | 112-118 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
| T29 | 366-372 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
| T30 | 383-395 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
| T31 | 608-620 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
| T32 | 674-697 | Disease | denotes | coronary artery disease | http://purl.obolibrary.org/obo/MONDO_0005010 |
| T33 | 683-697 | Disease | denotes | artery disease | http://purl.obolibrary.org/obo/MONDO_0000473 |
| T34 | 865-878 | Disease | denotes | Heart failure | http://purl.obolibrary.org/obo/MONDO_0005252 |
| T35 | 1056-1069 | Disease | denotes | heart failure | http://purl.obolibrary.org/obo/MONDO_0005252 |
| T36 | 1104-1120 | Disease | denotes | systemic disease | http://purl.obolibrary.org/obo/MONDO_0015938 |
| T37 | 1175-1188 | Disease | denotes | heart failure | http://purl.obolibrary.org/obo/MONDO_0005252 |
| T38 | 1189-1199 | Disease | denotes | Arrhythmia | http://purl.obolibrary.org/obo/MONDO_0007263 |
| T39 | 1424-1448 | Disease | denotes | coronavirus disease 2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T40 | 1511-1544 | Disease | denotes | Severe Acute Respiratory Syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T41 | 1675-1681 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
| T42 | 1864-1888 | Disease | denotes | coronavirus disease 2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T12 | 683-689 | http://purl.obolibrary.org/obo/UBERON_0001637 | denotes | artery |
| T13 | 683-689 | http://www.ebi.ac.uk/efo/EFO_0000814 | denotes | artery |
| T14 | 865-870 | http://purl.obolibrary.org/obo/UBERON_0000948 | denotes | Heart |
| T15 | 865-870 | http://purl.obolibrary.org/obo/UBERON_0007100 | denotes | Heart |
| T16 | 865-870 | http://purl.obolibrary.org/obo/UBERON_0015228 | denotes | Heart |
| T17 | 865-870 | http://www.ebi.ac.uk/efo/EFO_0000815 | denotes | Heart |
| T18 | 902-904 | http://purl.obolibrary.org/obo/CLO_0001407 | denotes | 52 |
| T19 | 1056-1061 | http://purl.obolibrary.org/obo/UBERON_0000948 | denotes | heart |
| T20 | 1056-1061 | http://purl.obolibrary.org/obo/UBERON_0007100 | denotes | heart |
| T21 | 1056-1061 | http://purl.obolibrary.org/obo/UBERON_0015228 | denotes | heart |
| T22 | 1056-1061 | http://www.ebi.ac.uk/efo/EFO_0000815 | denotes | heart |
| T23 | 1102-1103 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T24 | 1175-1180 | http://purl.obolibrary.org/obo/UBERON_0000948 | denotes | heart |
| T25 | 1175-1180 | http://purl.obolibrary.org/obo/UBERON_0007100 | denotes | heart |
| T26 | 1175-1180 | http://purl.obolibrary.org/obo/UBERON_0015228 | denotes | heart |
| T27 | 1175-1180 | http://www.ebi.ac.uk/efo/EFO_0000815 | denotes | heart |
| T28 | 1484-1485 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T29 | 1685-1686 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T30 | 1824-1827 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1 | 408-414 | Chemical | denotes | oxygen | http://purl.obolibrary.org/obo/CHEBI_25805 |
| T2 | 1591-1596 | Chemical | denotes | lipid | http://purl.obolibrary.org/obo/CHEBI_18059 |
| T3 | 1601-1608 | Chemical | denotes | glucose | http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T6 | 270-296 | Phenotype | denotes | cardiovascular abnormality | http://purl.obolibrary.org/obo/HP_0001626 |
| T7 | 698-735 | Phenotype | denotes | Left ventricular systolic dysfunction | http://purl.obolibrary.org/obo/HP_0025169 |
| T8 | 827-864 | Phenotype | denotes | left ventricular systolic dysfunction | http://purl.obolibrary.org/obo/HP_0025169 |
| T9 | 865-878 | Phenotype | denotes | Heart failure | http://purl.obolibrary.org/obo/HP_0001635 |
| T10 | 1056-1069 | Phenotype | denotes | heart failure | http://purl.obolibrary.org/obo/HP_0001635 |
| T11 | 1175-1188 | Phenotype | denotes | heart failure | http://purl.obolibrary.org/obo/HP_0001635 |
| T12 | 1189-1199 | Phenotype | denotes | Arrhythmia | http://purl.obolibrary.org/obo/HP_0011675 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T4 | 383-395 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
| T5 | 608-620 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
| T6 | 1601-1619 | http://purl.obolibrary.org/obo/GO_0006006 | denotes | glucose metabolism |
| T7 | 1609-1619 | http://purl.obolibrary.org/obo/GO_0008152 | denotes | metabolism |
| T8 | 1642-1653 | http://purl.obolibrary.org/obo/GO_0042592 | denotes | homeostasis |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T28 | 0-65 | Sentence | denotes | Table 1 Cardiovascular complications in coronavirus disease 2019. |
| T29 | 66-97 | Sentence | denotes | Manifestation Incidence Remarks |
| T30 | 98-296 | Sentence | denotes | Acute cardiac injury∗ (most commonly defined as elevation of cardiac troponin I above 99th percentile upper reference limit) 8–12% on average [10] • Most commonly reported cardiovascular abnormality |
| T31 | 297-372 | Sentence | denotes | • Can result from any of the following mechanisms-•Direct myocardial injury |
| T32 | 373-395 | Sentence | denotes | •Systemic inflammation |
| T33 | 396-437 | Sentence | denotes | •Myocardial oxygen demand supply mismatch |
| T34 | 438-459 | Sentence | denotes | •Acute coronary event |
| T35 | 460-471 | Sentence | denotes | •Iatrogenic |
| T36 | 472-505 | Sentence | denotes | • Strong adverse prognostic value |
| T37 | 506-643 | Sentence | denotes | Acute coronary event Not reported, but appears to be low Potential mechanisms-• Plaque rupture due to inflammation/increased shear stress |
| T38 | 644-697 | Sentence | denotes | • Aggravation of pre-existing coronary artery disease |
| T39 | 698-864 | Sentence | denotes | Left ventricular systolic dysfunction Not reported Any of the causes of myocardial dysfunction mentioned above can lead to acute left ventricular systolic dysfunction |
| T40 | 865-1069 | Sentence | denotes | Heart failure Reported in one study- 52% in those who died, 12% in those who recovered and were discharged [5] • Any of the causes of myocardial dysfunction mentioned above can lead to acute heart failure |
| T41 | 1070-1188 | Sentence | denotes | • Increased metabolic demand of a systemic disease can cause acute decompensation of pre-existing stable heart failure |
| T42 | 1189-1343 | Sentence | denotes | Arrhythmia 16.7% overall; 44.4 in severe illness, 8.9% in mild cases [8] Both tachyarrhythmia and bradyarrhythmia can occur but exact nature not described |
| T43 | 1344-1449 | Sentence | denotes | Potential long-term consequences Too early to assess Too early to ascertain for coronavirus disease 2019. |
| T44 | 1450-1658 | Sentence | denotes | However, patients recovering from a similar earlier illness- Severe Acute Respiratory Syndrome- continued to have long-term abnormalities of lipid and glucose metabolism and of cardiovascular homeostasis [12] |
| T45 | 1659-1889 | Sentence | denotes | ∗ Acute cardiac injury is a non-specific term with significant overlap with other cardiovascular manifestations; however, it is listed here because of how reporting has been done in most of the studies on coronavirus disease 2019. |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T44 | 40-51 | NCBITaxon:11118 | denotes | coronavirus |
| T45 | 104-111 | UBERON:0000948 | denotes | cardiac |
| T46 | 159-166 | UBERON:0000948 | denotes | cardiac |
| T47 | 270-284 | UBERON:0004535 | denotes | cardiovascular |
| T48 | 355-365 | UBERON:0002349 | denotes | myocardial |
| T49 | 397-407 | UBERON:0002349 | denotes | Myocardial |
| T50 | 445-453 | UBERON:0001621 | denotes | coronary |
| T51 | 512-520 | UBERON:0001621 | denotes | coronary |
| T52 | 674-689 | UBERON:0001621 | denotes | coronary artery |
| T53 | 703-714 | UBERON:0002082 | denotes | ventricular |
| T54 | 770-780 | UBERON:0002349 | denotes | myocardial |
| T55 | 827-843 | UBERON:0002084 | denotes | left ventricular |
| T56 | 919-923 | GO:0016265 | denotes | died |
| T57 | 999-1009 | UBERON:0002349 | denotes | myocardial |
| T58 | 1056-1061 | UBERON:0000948 | denotes | heart |
| T59 | 1082-1091 | GO:0008152 | denotes | metabolic |
| T60 | 1175-1180 | UBERON:0000948 | denotes | heart |
| T61 | 1424-1435 | NCBITaxon:11118 | denotes | coronavirus |
| T62 | 1591-1596 | CHEBI:18059;CHEBI:18059;GO:0006629 | denotes | lipid |
| T63 | 1601-1608 | CHEBI:17234;CHEBI:17234;GO:0006006 | denotes | glucose |
| T64 | 1609-1619 | GO:0006006 | denotes | metabolism |
| T65 | 1627-1641 | UBERON:0004535 | denotes | cardiovascular |
| T66 | 1642-1653 | GO:0042592 | denotes | homeostasis |
| T67 | 1667-1674 | UBERON:0000948 | denotes | cardiac |
| T68 | 1741-1755 | UBERON:0004535 | denotes | cardiovascular |
| T69 | 1864-1875 | NCBITaxon:11118 | denotes | coronavirus |
| T33 | 1667-1674 | UBERON:0000948 | denotes | cardiac |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32247212-28831119-25241177 | 1655-1657 | 28831119 | denotes | 12 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 90 | 159-177 | Gene | denotes | cardiac troponin I | Gene:7137 |
| 91 | 1459-1467 | Species | denotes | patients | Tax:9606 |
| 92 | 104-118 | Disease | denotes | cardiac injury | MESH:D006331 |
| 93 | 270-302 | Disease | denotes | cardiovascular abnormality • Can | MESH:D002318 |
| 94 | 355-395 | Disease | denotes | myocardial injury •Systemic inflammation | MESH:D009202 |
| 95 | 608-620 | Disease | denotes | inflammation | MESH:D007249 |
| 96 | 674-697 | Disease | denotes | coronary artery disease | MESH:D003324 |
| 97 | 698-735 | Disease | denotes | Left ventricular systolic dysfunction | MESH:D018487 |
| 98 | 770-792 | Disease | denotes | myocardial dysfunction | MESH:D009202 |
| 99 | 827-878 | Disease | denotes | left ventricular systolic dysfunction Heart failure | MESH:D006333 |
| 100 | 919-923 | Disease | denotes | died | MESH:D003643 |
| 101 | 999-1021 | Disease | denotes | myocardial dysfunction | MESH:D009202 |
| 102 | 1056-1098 | Disease | denotes | heart failure • Increased metabolic demand | MESH:D008659 |
| 103 | 1175-1199 | Disease | denotes | heart failure Arrhythmia | MESH:D001145 |
| 104 | 1267-1302 | Disease | denotes | tachyarrhythmia and bradyarrhythmia | MESH:D001919 |
| 105 | 1424-1448 | Disease | denotes | coronavirus disease 2019 | MESH:C000657245 |
| 106 | 1574-1619 | Disease | denotes | abnormalities of lipid and glucose metabolism | MESH:D044882 |
| 107 | 1627-1653 | Disease | denotes | cardiovascular homeostasis | MESH:D002318 |
| 109 | 40-64 | Disease | denotes | coronavirus disease 2019 | MESH:C000657245 |
| 112 | 1667-1681 | Disease | denotes | cardiac injury | MESH:D006331 |
| 113 | 1864-1888 | Disease | denotes | coronavirus disease 2019 | MESH:C000657245 |