PMC:7102662 / 2121-4809
Annnotations
LitCovid_Glycan-Motif-Structure
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 2400-2407 | https://glytoucan.org/Structures/Glycans/G15021LG | denotes | glucose |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T3 | 966-976 | Body_part | denotes | troponin I | http://purl.org/sig/ont/fma/fma62340 |
T4 | 966-974 | Body_part | denotes | troponin | http://purl.org/sig/ont/fma/fma62338 |
T5 | 1473-1488 | Body_part | denotes | coronary artery | http://purl.org/sig/ont/fma/fma49893 |
T6 | 1664-1669 | Body_part | denotes | Heart | http://purl.org/sig/ont/fma/fma7088 |
T7 | 1855-1860 | Body_part | denotes | heart | http://purl.org/sig/ont/fma/fma7088 |
T8 | 1974-1979 | Body_part | denotes | heart | http://purl.org/sig/ont/fma/fma7088 |
T9 | 2390-2395 | Body_part | denotes | lipid | http://purl.org/sig/ont/fma/fma67264 |
T10 | 2400-2407 | Body_part | denotes | glucose | http://purl.org/sig/ont/fma/fma82743 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 1473-1488 | Body_part | denotes | coronary artery | http://purl.obolibrary.org/obo/UBERON_0001621 |
T2 | 1482-1488 | Body_part | denotes | artery | http://purl.obolibrary.org/obo/UBERON_0001637 |
T3 | 1664-1669 | Body_part | denotes | Heart | http://purl.obolibrary.org/obo/UBERON_0000948 |
T4 | 1855-1860 | Body_part | denotes | heart | http://purl.obolibrary.org/obo/UBERON_0000948 |
T5 | 1974-1979 | Body_part | denotes | heart | http://purl.obolibrary.org/obo/UBERON_0000948 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T21 | 56-103 | Disease | denotes | Severe Acute Respiratory Syndrome-Coronavirus-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T22 | 56-89 | Disease | denotes | Severe Acute Respiratory Syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
T23 | 105-113 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T24 | 452-476 | Disease | denotes | coronavirus disease 2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T25 | 478-488 | Disease | denotes | COVID-2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T26 | 615-624 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T27 | 839-863 | Disease | denotes | coronavirus disease 2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T28 | 911-917 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
T29 | 1165-1171 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
T30 | 1182-1194 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
T31 | 1407-1419 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
T32 | 1473-1496 | Disease | denotes | coronary artery disease | http://purl.obolibrary.org/obo/MONDO_0005010 |
T33 | 1482-1496 | Disease | denotes | artery disease | http://purl.obolibrary.org/obo/MONDO_0000473 |
T34 | 1664-1677 | Disease | denotes | Heart failure | http://purl.obolibrary.org/obo/MONDO_0005252 |
T35 | 1855-1868 | Disease | denotes | heart failure | http://purl.obolibrary.org/obo/MONDO_0005252 |
T36 | 1903-1919 | Disease | denotes | systemic disease | http://purl.obolibrary.org/obo/MONDO_0015938 |
T37 | 1974-1987 | Disease | denotes | heart failure | http://purl.obolibrary.org/obo/MONDO_0005252 |
T38 | 1988-1998 | Disease | denotes | Arrhythmia | http://purl.obolibrary.org/obo/MONDO_0007263 |
T39 | 2223-2247 | Disease | denotes | coronavirus disease 2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T40 | 2310-2343 | Disease | denotes | Severe Acute Respiratory Syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
T41 | 2474-2480 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
T42 | 2663-2687 | Disease | denotes | coronavirus disease 2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T6 | 118-121 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T7 | 355-360 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T8 | 399-400 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T9 | 575-576 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T10 | 625-628 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T11 | 747-759 | http://purl.obolibrary.org/obo/OBI_0000245 | denotes | Organization |
T12 | 1482-1488 | http://purl.obolibrary.org/obo/UBERON_0001637 | denotes | artery |
T13 | 1482-1488 | http://www.ebi.ac.uk/efo/EFO_0000814 | denotes | artery |
T14 | 1664-1669 | http://purl.obolibrary.org/obo/UBERON_0000948 | denotes | Heart |
T15 | 1664-1669 | http://purl.obolibrary.org/obo/UBERON_0007100 | denotes | Heart |
T16 | 1664-1669 | http://purl.obolibrary.org/obo/UBERON_0015228 | denotes | Heart |
T17 | 1664-1669 | http://www.ebi.ac.uk/efo/EFO_0000815 | denotes | Heart |
T18 | 1701-1703 | http://purl.obolibrary.org/obo/CLO_0001407 | denotes | 52 |
T19 | 1855-1860 | http://purl.obolibrary.org/obo/UBERON_0000948 | denotes | heart |
T20 | 1855-1860 | http://purl.obolibrary.org/obo/UBERON_0007100 | denotes | heart |
T21 | 1855-1860 | http://purl.obolibrary.org/obo/UBERON_0015228 | denotes | heart |
T22 | 1855-1860 | http://www.ebi.ac.uk/efo/EFO_0000815 | denotes | heart |
T23 | 1901-1902 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T24 | 1974-1979 | http://purl.obolibrary.org/obo/UBERON_0000948 | denotes | heart |
T25 | 1974-1979 | http://purl.obolibrary.org/obo/UBERON_0007100 | denotes | heart |
T26 | 1974-1979 | http://purl.obolibrary.org/obo/UBERON_0015228 | denotes | heart |
T27 | 1974-1979 | http://www.ebi.ac.uk/efo/EFO_0000815 | denotes | heart |
T28 | 2283-2284 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T29 | 2484-2485 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T30 | 2623-2626 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T1 | 1207-1213 | Chemical | denotes | oxygen | http://purl.obolibrary.org/obo/CHEBI_25805 |
T2 | 2390-2395 | Chemical | denotes | lipid | http://purl.obolibrary.org/obo/CHEBI_18059 |
T3 | 2400-2407 | Chemical | denotes | glucose | http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167 |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T6 | 1069-1095 | Phenotype | denotes | cardiovascular abnormality | http://purl.obolibrary.org/obo/HP_0001626 |
T7 | 1497-1534 | Phenotype | denotes | Left ventricular systolic dysfunction | http://purl.obolibrary.org/obo/HP_0025169 |
T8 | 1626-1663 | Phenotype | denotes | left ventricular systolic dysfunction | http://purl.obolibrary.org/obo/HP_0025169 |
T9 | 1664-1677 | Phenotype | denotes | Heart failure | http://purl.obolibrary.org/obo/HP_0001635 |
T10 | 1855-1868 | Phenotype | denotes | heart failure | http://purl.obolibrary.org/obo/HP_0001635 |
T11 | 1974-1987 | Phenotype | denotes | heart failure | http://purl.obolibrary.org/obo/HP_0001635 |
T12 | 1988-1998 | Phenotype | denotes | Arrhythmia | http://purl.obolibrary.org/obo/HP_0011675 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2 | 301-310 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | virulence |
T3 | 301-310 | http://purl.obolibrary.org/obo/GO_0009405 | denotes | virulence |
T4 | 1182-1194 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
T5 | 1407-1419 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
T6 | 2400-2418 | http://purl.obolibrary.org/obo/GO_0006006 | denotes | glucose metabolism |
T7 | 2408-2418 | http://purl.obolibrary.org/obo/GO_0008152 | denotes | metabolism |
T8 | 2441-2452 | http://purl.obolibrary.org/obo/GO_0042592 | denotes | homeostasis |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T24 | 0-205 | Sentence | denotes | The emergence of novel coronavirus, officially known as Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2), has presented an unprecedented challenge for the healthcare community across the world. |
T25 | 206-410 | Sentence | denotes | High infectivity, ability to get transmitted even during asymptomatic phase and relatively low virulence have resulted in rapid transmission of this virus beyond geographic regions, leading to a pandemic. |
T26 | 411-555 | Sentence | denotes | The first case of this disease, known as coronavirus disease 2019 (COVID-2019), occurred on December 8, 2019 in the Hubei province of China [1]. |
T27 | 556-798 | Sentence | denotes | Since then, within a short span of just over 3 months, the infection has spread to 177 countries/area/territories across the world, with 266073 confirmed cases and 11184 deaths (World Health Organization statistics as on March 21, 2020) [2] . |
T28 | 799-864 | Sentence | denotes | Table 1 Cardiovascular complications in coronavirus disease 2019. |
T29 | 865-896 | Sentence | denotes | Manifestation Incidence Remarks |
T30 | 897-1095 | Sentence | denotes | Acute cardiac injury∗ (most commonly defined as elevation of cardiac troponin I above 99th percentile upper reference limit) 8–12% on average [10] • Most commonly reported cardiovascular abnormality |
T31 | 1096-1171 | Sentence | denotes | • Can result from any of the following mechanisms-•Direct myocardial injury |
T32 | 1172-1194 | Sentence | denotes | •Systemic inflammation |
T33 | 1195-1236 | Sentence | denotes | •Myocardial oxygen demand supply mismatch |
T34 | 1237-1258 | Sentence | denotes | •Acute coronary event |
T35 | 1259-1270 | Sentence | denotes | •Iatrogenic |
T36 | 1271-1304 | Sentence | denotes | • Strong adverse prognostic value |
T37 | 1305-1442 | Sentence | denotes | Acute coronary event Not reported, but appears to be low Potential mechanisms-• Plaque rupture due to inflammation/increased shear stress |
T38 | 1443-1496 | Sentence | denotes | • Aggravation of pre-existing coronary artery disease |
T39 | 1497-1663 | Sentence | denotes | Left ventricular systolic dysfunction Not reported Any of the causes of myocardial dysfunction mentioned above can lead to acute left ventricular systolic dysfunction |
T40 | 1664-1868 | Sentence | denotes | Heart failure Reported in one study- 52% in those who died, 12% in those who recovered and were discharged [5] • Any of the causes of myocardial dysfunction mentioned above can lead to acute heart failure |
T41 | 1869-1987 | Sentence | denotes | • Increased metabolic demand of a systemic disease can cause acute decompensation of pre-existing stable heart failure |
T42 | 1988-2142 | Sentence | denotes | Arrhythmia 16.7% overall; 44.4 in severe illness, 8.9% in mild cases [8] Both tachyarrhythmia and bradyarrhythmia can occur but exact nature not described |
T43 | 2143-2248 | Sentence | denotes | Potential long-term consequences Too early to assess Too early to ascertain for coronavirus disease 2019. |
T44 | 2249-2457 | Sentence | denotes | However, patients recovering from a similar earlier illness- Severe Acute Respiratory Syndrome- continued to have long-term abnormalities of lipid and glucose metabolism and of cardiovascular homeostasis [12] |
T45 | 2458-2688 | Sentence | denotes | ∗ Acute cardiac injury is a non-specific term with significant overlap with other cardiovascular manifestations; however, it is listed here because of how reporting has been done in most of the studies on coronavirus disease 2019. |
LitCovid-PMC-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T38 | 23-34 | NCBITaxon:11118 | denotes | coronavirus |
T39 | 56-103 | SP_7 | denotes | Severe Acute Respiratory Syndrome-Coronavirus-2 |
T40 | 105-115 | SP_7 | denotes | SARS-CoV-2 |
T41 | 355-360 | NCBITaxon:10239 | denotes | virus |
T42 | 452-463 | NCBITaxon:11118 | denotes | coronavirus |
T43 | 726-732 | GO:0016265 | denotes | deaths |
T44 | 839-850 | NCBITaxon:11118 | denotes | coronavirus |
T45 | 903-910 | UBERON:0000948 | denotes | cardiac |
T46 | 958-965 | UBERON:0000948 | denotes | cardiac |
T47 | 1069-1083 | UBERON:0004535 | denotes | cardiovascular |
T48 | 1154-1164 | UBERON:0002349 | denotes | myocardial |
T49 | 1196-1206 | UBERON:0002349 | denotes | Myocardial |
T50 | 1244-1252 | UBERON:0001621 | denotes | coronary |
T51 | 1311-1319 | UBERON:0001621 | denotes | coronary |
T52 | 1473-1488 | UBERON:0001621 | denotes | coronary artery |
T53 | 1502-1513 | UBERON:0002082 | denotes | ventricular |
T54 | 1569-1579 | UBERON:0002349 | denotes | myocardial |
T55 | 1626-1642 | UBERON:0002084 | denotes | left ventricular |
T56 | 1718-1722 | GO:0016265 | denotes | died |
T57 | 1798-1808 | UBERON:0002349 | denotes | myocardial |
T58 | 1855-1860 | UBERON:0000948 | denotes | heart |
T59 | 1881-1890 | GO:0008152 | denotes | metabolic |
T60 | 1974-1979 | UBERON:0000948 | denotes | heart |
T61 | 2223-2234 | NCBITaxon:11118 | denotes | coronavirus |
T62 | 2390-2395 | CHEBI:18059;CHEBI:18059;GO:0006629 | denotes | lipid |
T63 | 2400-2407 | CHEBI:17234;CHEBI:17234;GO:0006006 | denotes | glucose |
T64 | 2408-2418 | GO:0006006 | denotes | metabolism |
T65 | 2426-2440 | UBERON:0004535 | denotes | cardiovascular |
T66 | 2441-2452 | GO:0042592 | denotes | homeostasis |
T67 | 2466-2473 | UBERON:0000948 | denotes | cardiac |
T68 | 2540-2554 | UBERON:0004535 | denotes | cardiovascular |
T69 | 2663-2674 | NCBITaxon:11118 | denotes | coronavirus |
T33 | 2466-2473 | UBERON:0000948 | denotes | cardiac |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32247212-28831119-25241177 | 2454-2456 | 28831119 | denotes | 12 |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
90 | 958-976 | Gene | denotes | cardiac troponin I | Gene:7137 |
91 | 2258-2266 | Species | denotes | patients | Tax:9606 |
92 | 903-917 | Disease | denotes | cardiac injury | MESH:D006331 |
93 | 1069-1101 | Disease | denotes | cardiovascular abnormality • Can | MESH:D002318 |
94 | 1154-1194 | Disease | denotes | myocardial injury •Systemic inflammation | MESH:D009202 |
95 | 1407-1419 | Disease | denotes | inflammation | MESH:D007249 |
96 | 1473-1496 | Disease | denotes | coronary artery disease | MESH:D003324 |
97 | 1497-1534 | Disease | denotes | Left ventricular systolic dysfunction | MESH:D018487 |
98 | 1569-1591 | Disease | denotes | myocardial dysfunction | MESH:D009202 |
99 | 1626-1677 | Disease | denotes | left ventricular systolic dysfunction Heart failure | MESH:D006333 |
100 | 1718-1722 | Disease | denotes | died | MESH:D003643 |
101 | 1798-1820 | Disease | denotes | myocardial dysfunction | MESH:D009202 |
102 | 1855-1897 | Disease | denotes | heart failure • Increased metabolic demand | MESH:D008659 |
103 | 1974-1998 | Disease | denotes | heart failure Arrhythmia | MESH:D001145 |
104 | 2066-2101 | Disease | denotes | tachyarrhythmia and bradyarrhythmia | MESH:D001919 |
105 | 2223-2247 | Disease | denotes | coronavirus disease 2019 | MESH:C000657245 |
106 | 2373-2418 | Disease | denotes | abnormalities of lipid and glucose metabolism | MESH:D044882 |
107 | 2426-2452 | Disease | denotes | cardiovascular homeostasis | MESH:D002318 |
109 | 839-863 | Disease | denotes | coronavirus disease 2019 | MESH:C000657245 |
112 | 2466-2480 | Disease | denotes | cardiac injury | MESH:D006331 |
113 | 2663-2687 | Disease | denotes | coronavirus disease 2019 | MESH:C000657245 |
121 | 17-34 | Species | denotes | novel coronavirus | Tax:2697049 |
122 | 56-103 | Species | denotes | Severe Acute Respiratory Syndrome-Coronavirus-2 | Tax:2697049 |
123 | 105-115 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
124 | 452-476 | Disease | denotes | coronavirus disease 2019 | MESH:C000657245 |
125 | 478-488 | Disease | denotes | COVID-2019 | MESH:C000657245 |
126 | 615-624 | Disease | denotes | infection | MESH:D007239 |
127 | 726-732 | Disease | denotes | deaths | MESH:D003643 |