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LitCovid_Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 2416-2423 https://glytoucan.org/Structures/Glycans/G15021LG denotes glucose

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T3 982-992 Body_part denotes troponin I http://purl.org/sig/ont/fma/fma62340
T4 982-990 Body_part denotes troponin http://purl.org/sig/ont/fma/fma62338
T5 1489-1504 Body_part denotes coronary artery http://purl.org/sig/ont/fma/fma49893
T6 1680-1685 Body_part denotes Heart http://purl.org/sig/ont/fma/fma7088
T7 1871-1876 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T8 1990-1995 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T9 2406-2411 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T10 2416-2423 Body_part denotes glucose http://purl.org/sig/ont/fma/fma82743
T11 2928-2945 Body_part denotes respiratory tract http://purl.org/sig/ont/fma/fma265130

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 1489-1504 Body_part denotes coronary artery http://purl.obolibrary.org/obo/UBERON_0001621
T2 1498-1504 Body_part denotes artery http://purl.obolibrary.org/obo/UBERON_0001637
T3 1680-1685 Body_part denotes Heart http://purl.obolibrary.org/obo/UBERON_0000948
T4 1871-1876 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T5 1990-1995 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T6 2928-2945 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T21 72-119 Disease denotes Severe Acute Respiratory Syndrome-Coronavirus-2 http://purl.obolibrary.org/obo/MONDO_0100096
T22 72-105 Disease denotes Severe Acute Respiratory Syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T23 121-129 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T24 468-492 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T25 494-504 Disease denotes COVID-2019 http://purl.obolibrary.org/obo/MONDO_0100096
T26 631-640 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T27 855-879 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T28 927-933 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T29 1181-1187 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T30 1198-1210 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T31 1423-1435 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T32 1489-1512 Disease denotes coronary artery disease http://purl.obolibrary.org/obo/MONDO_0005010
T33 1498-1512 Disease denotes artery disease http://purl.obolibrary.org/obo/MONDO_0000473
T34 1680-1693 Disease denotes Heart failure http://purl.obolibrary.org/obo/MONDO_0005252
T35 1871-1884 Disease denotes heart failure http://purl.obolibrary.org/obo/MONDO_0005252
T36 1919-1935 Disease denotes systemic disease http://purl.obolibrary.org/obo/MONDO_0015938
T37 1990-2003 Disease denotes heart failure http://purl.obolibrary.org/obo/MONDO_0005252
T38 2004-2014 Disease denotes Arrhythmia http://purl.obolibrary.org/obo/MONDO_0007263
T39 2239-2263 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T40 2326-2359 Disease denotes Severe Acute Respiratory Syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T41 2490-2496 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T42 2679-2703 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T43 2787-2822 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T44 2793-2822 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T45 2836-2845 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T46 2889-2897 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T47 2928-2955 Disease denotes respiratory tract infection http://purl.obolibrary.org/obo/MONDO_0024355
T48 2946-2955 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T49 2970-2998 Disease denotes cardiovascular disease (CVD) http://purl.obolibrary.org/obo/MONDO_0004995
T50 3044-3052 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T51 3063-3071 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T52 3250-3258 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T53 3559-3567 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T54 3630-3634 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T6 134-137 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T7 371-376 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T8 415-416 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T9 591-592 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T10 641-644 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T11 763-775 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T12 1498-1504 http://purl.obolibrary.org/obo/UBERON_0001637 denotes artery
T13 1498-1504 http://www.ebi.ac.uk/efo/EFO_0000814 denotes artery
T14 1680-1685 http://purl.obolibrary.org/obo/UBERON_0000948 denotes Heart
T15 1680-1685 http://purl.obolibrary.org/obo/UBERON_0007100 denotes Heart
T16 1680-1685 http://purl.obolibrary.org/obo/UBERON_0015228 denotes Heart
T17 1680-1685 http://www.ebi.ac.uk/efo/EFO_0000815 denotes Heart
T18 1717-1719 http://purl.obolibrary.org/obo/CLO_0001407 denotes 52
T19 1871-1876 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T20 1871-1876 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T21 1871-1876 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T22 1871-1876 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T23 1917-1918 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T24 1990-1995 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T25 1990-1995 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T26 1990-1995 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T27 1990-1995 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T28 2299-2300 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T29 2500-2501 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T30 2639-2642 http://purl.obolibrary.org/obo/CLO_0051582 denotes has

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 1223-1229 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T2 2406-2411 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T3 2416-2423 Chemical denotes glucose http://purl.obolibrary.org/obo/CHEBI_17234|http://purl.obolibrary.org/obo/CHEBI_4167

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T6 1085-1111 Phenotype denotes cardiovascular abnormality http://purl.obolibrary.org/obo/HP_0001626
T7 1513-1550 Phenotype denotes Left ventricular systolic dysfunction http://purl.obolibrary.org/obo/HP_0025169
T8 1642-1679 Phenotype denotes left ventricular systolic dysfunction http://purl.obolibrary.org/obo/HP_0025169
T9 1680-1693 Phenotype denotes Heart failure http://purl.obolibrary.org/obo/HP_0001635
T10 1871-1884 Phenotype denotes heart failure http://purl.obolibrary.org/obo/HP_0001635
T11 1990-2003 Phenotype denotes heart failure http://purl.obolibrary.org/obo/HP_0001635
T12 2004-2014 Phenotype denotes Arrhythmia http://purl.obolibrary.org/obo/HP_0011675
T13 2793-2813 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T14 2836-2845 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T15 2928-2955 Phenotype denotes respiratory tract infection http://purl.obolibrary.org/obo/HP_0011947
T16 2970-2992 Phenotype denotes cardiovascular disease http://purl.obolibrary.org/obo/HP_0001626

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T2 317-326 http://purl.obolibrary.org/obo/GO_0016032 denotes virulence
T3 317-326 http://purl.obolibrary.org/obo/GO_0009405 denotes virulence
T4 1198-1210 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T5 1423-1435 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T6 2416-2434 http://purl.obolibrary.org/obo/GO_0006006 denotes glucose metabolism
T7 2424-2434 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T8 2457-2468 http://purl.obolibrary.org/obo/GO_0042592 denotes homeostasis
T9 3572-3581 http://purl.obolibrary.org/obo/GO_0007612 denotes learnings

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T23 0-15 Sentence denotes 1 Introduction
T24 16-221 Sentence denotes The emergence of novel coronavirus, officially known as Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2), has presented an unprecedented challenge for the healthcare community across the world.
T25 222-426 Sentence denotes High infectivity, ability to get transmitted even during asymptomatic phase and relatively low virulence have resulted in rapid transmission of this virus beyond geographic regions, leading to a pandemic.
T26 427-571 Sentence denotes The first case of this disease, known as coronavirus disease 2019 (COVID-2019), occurred on December 8, 2019 in the Hubei province of China [1].
T27 572-814 Sentence denotes Since then, within a short span of just over 3 months, the infection has spread to 177 countries/area/territories across the world, with 266073 confirmed cases and 11184 deaths (World Health Organization statistics as on March 21, 2020) [2] .
T28 815-880 Sentence denotes Table 1 Cardiovascular complications in coronavirus disease 2019.
T29 881-912 Sentence denotes Manifestation Incidence Remarks
T30 913-1111 Sentence denotes Acute cardiac injury∗ (most commonly defined as elevation of cardiac troponin I above 99th percentile upper reference limit) 8–12% on average [10] • Most commonly reported cardiovascular abnormality
T31 1112-1187 Sentence denotes • Can result from any of the following mechanisms-•Direct myocardial injury
T32 1188-1210 Sentence denotes •Systemic inflammation
T33 1211-1252 Sentence denotes •Myocardial oxygen demand supply mismatch
T34 1253-1274 Sentence denotes •Acute coronary event
T35 1275-1286 Sentence denotes •Iatrogenic
T36 1287-1320 Sentence denotes • Strong adverse prognostic value
T37 1321-1458 Sentence denotes Acute coronary event Not reported, but appears to be low Potential mechanisms-• Plaque rupture due to inflammation/increased shear stress
T38 1459-1512 Sentence denotes • Aggravation of pre-existing coronary artery disease
T39 1513-1679 Sentence denotes Left ventricular systolic dysfunction Not reported Any of the causes of myocardial dysfunction mentioned above can lead to acute left ventricular systolic dysfunction
T40 1680-1884 Sentence denotes Heart failure Reported in one study- 52% in those who died, 12% in those who recovered and were discharged [5] • Any of the causes of myocardial dysfunction mentioned above can lead to acute heart failure
T41 1885-2003 Sentence denotes • Increased metabolic demand of a systemic disease can cause acute decompensation of pre-existing stable heart failure
T42 2004-2158 Sentence denotes Arrhythmia 16.7% overall; 44.4 in severe illness, 8.9% in mild cases [8] Both tachyarrhythmia and bradyarrhythmia can occur but exact nature not described
T43 2159-2264 Sentence denotes Potential long-term consequences Too early to assess Too early to ascertain for coronavirus disease 2019.
T44 2265-2473 Sentence denotes However, patients recovering from a similar earlier illness- Severe Acute Respiratory Syndrome- continued to have long-term abnormalities of lipid and glucose metabolism and of cardiovascular homeostasis [12]
T45 2474-2704 Sentence denotes ∗ Acute cardiac injury is a non-specific term with significant overlap with other cardiovascular manifestations; however, it is listed here because of how reporting has been done in most of the studies on coronavirus disease 2019.
T46 2705-2898 Sentence denotes Respiratory involvement, presenting as mild flulike illness to potentially lethal acute respiratory distress syndrome or fulminant pneumonia, is the dominant clinical manifestation of COVID-19.
T47 2899-3053 Sentence denotes However, much like any other respiratory tract infection, pre-existing cardiovascular disease (CVD) and CV risk factors enhance vulnerability to COVID-19.
T48 3054-3149 Sentence denotes Further, COVID-19 can worsen underlying CVD and even precipitate de novo cardiac complications.
T49 3150-3259 Sentence denotes This review is aimed at providing overview of various CV manifestations in patients presenting with COVID-19.
T50 3260-3384 Sentence denotes The impact of pre-existing CVD and new onset cardiac complications on clinical outcomes in these patients is also discussed.
T51 3385-3679 Sentence denotes Since our understanding on this subject is only evolving at this stage, the information contained in the subsequent text is based mainly on the limited early experience with COVID-19 and learnings from the previous coronavirus illnesses, namely SARS and Middle-East Respiratory Syndrome (MERS).

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T38 39-50 NCBITaxon:11118 denotes coronavirus
T39 72-119 SP_7 denotes Severe Acute Respiratory Syndrome-Coronavirus-2
T40 121-131 SP_7 denotes SARS-CoV-2
T41 371-376 NCBITaxon:10239 denotes virus
T42 468-479 NCBITaxon:11118 denotes coronavirus
T43 742-748 GO:0016265 denotes deaths
T44 855-866 NCBITaxon:11118 denotes coronavirus
T45 919-926 UBERON:0000948 denotes cardiac
T46 974-981 UBERON:0000948 denotes cardiac
T47 1085-1099 UBERON:0004535 denotes cardiovascular
T48 1170-1180 UBERON:0002349 denotes myocardial
T49 1212-1222 UBERON:0002349 denotes Myocardial
T50 1260-1268 UBERON:0001621 denotes coronary
T51 1327-1335 UBERON:0001621 denotes coronary
T52 1489-1504 UBERON:0001621 denotes coronary artery
T53 1518-1529 UBERON:0002082 denotes ventricular
T54 1585-1595 UBERON:0002349 denotes myocardial
T55 1642-1658 UBERON:0002084 denotes left ventricular
T56 1734-1738 GO:0016265 denotes died
T57 1814-1824 UBERON:0002349 denotes myocardial
T58 1871-1876 UBERON:0000948 denotes heart
T59 1897-1906 GO:0008152 denotes metabolic
T60 1990-1995 UBERON:0000948 denotes heart
T61 2239-2250 NCBITaxon:11118 denotes coronavirus
T62 2406-2411 CHEBI:18059;CHEBI:18059;GO:0006629 denotes lipid
T63 2416-2423 CHEBI:17234;CHEBI:17234;GO:0006006 denotes glucose
T64 2424-2434 GO:0006006 denotes metabolism
T65 2442-2456 UBERON:0004535 denotes cardiovascular
T66 2457-2468 GO:0042592 denotes homeostasis
T67 2482-2489 UBERON:0000948 denotes cardiac
T68 2556-2570 UBERON:0004535 denotes cardiovascular
T69 2679-2690 NCBITaxon:11118 denotes coronavirus
T88 2793-2804 UBERON:0001004 denotes respiratory
T89 2889-2897 SP_7 denotes COVID-19
T90 2928-2945 UBERON:0000065 denotes respiratory tract
T91 2970-2984 UBERON:0004535 denotes cardiovascular
T92 3044-3052 SP_7 denotes COVID-19
T93 3063-3071 SP_7 denotes COVID-19
T94 3127-3134 UBERON:0000948 denotes cardiac
T95 3250-3258 SP_7 denotes COVID-19
T96 3305-3312 UBERON:0000948 denotes cardiac
T97 3559-3567 SP_7 denotes COVID-19
T98 3572-3581 GO:0007612 denotes learnings
T99 3600-3611 NCBITaxon:11118 denotes coronavirus
T100 3630-3634 SP_10 denotes SARS
T101 3673-3677 SP_9 denotes MERS
T33 2482-2489 UBERON:0000948 denotes cardiac

2_test

Id Subject Object Predicate Lexical cue
32247212-28831119-25241177 2470-2472 28831119 denotes 12

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
90 974-992 Gene denotes cardiac troponin I Gene:7137
91 2274-2282 Species denotes patients Tax:9606
92 919-933 Disease denotes cardiac injury MESH:D006331
93 1085-1117 Disease denotes cardiovascular abnormality • Can MESH:D002318
94 1170-1210 Disease denotes myocardial injury •Systemic inflammation MESH:D009202
95 1423-1435 Disease denotes inflammation MESH:D007249
96 1489-1512 Disease denotes coronary artery disease MESH:D003324
97 1513-1550 Disease denotes Left ventricular systolic dysfunction MESH:D018487
98 1585-1607 Disease denotes myocardial dysfunction MESH:D009202
99 1642-1693 Disease denotes left ventricular systolic dysfunction Heart failure MESH:D006333
100 1734-1738 Disease denotes died MESH:D003643
101 1814-1836 Disease denotes myocardial dysfunction MESH:D009202
102 1871-1913 Disease denotes heart failure • Increased metabolic demand MESH:D008659
103 1990-2014 Disease denotes heart failure Arrhythmia MESH:D001145
104 2082-2117 Disease denotes tachyarrhythmia and bradyarrhythmia MESH:D001919
105 2239-2263 Disease denotes coronavirus disease 2019 MESH:C000657245
106 2389-2434 Disease denotes abnormalities of lipid and glucose metabolism MESH:D044882
107 2442-2468 Disease denotes cardiovascular homeostasis MESH:D002318
109 855-879 Disease denotes coronavirus disease 2019 MESH:C000657245
112 2482-2496 Disease denotes cardiac injury MESH:D006331
113 2679-2703 Disease denotes coronavirus disease 2019 MESH:C000657245
121 33-50 Species denotes novel coronavirus Tax:2697049
122 72-119 Species denotes Severe Acute Respiratory Syndrome-Coronavirus-2 Tax:2697049
123 121-131 Species denotes SARS-CoV-2 Tax:2697049
124 468-492 Disease denotes coronavirus disease 2019 MESH:C000657245
125 494-504 Disease denotes COVID-2019 MESH:C000657245
126 631-640 Disease denotes infection MESH:D007239
127 742-748 Disease denotes deaths MESH:D003643
139 2749-2764 Disease denotes flulike illness MESH:D002908
140 2787-2822 Disease denotes acute respiratory distress syndrome MESH:D012128
141 2836-2845 Disease denotes pneumonia MESH:D011014
142 2889-2897 Disease denotes COVID-19 MESH:C000657245
143 2928-2955 Disease denotes respiratory tract infection MESH:D012141
144 2970-2992 Disease denotes cardiovascular disease MESH:D002318
145 2994-2997 Disease denotes CVD MESH:D002318
146 3044-3052 Disease denotes COVID-19 MESH:C000657245
147 3063-3071 Disease denotes COVID-19 MESH:C000657245
148 3094-3097 Disease denotes CVD MESH:D002318
149 3127-3148 Disease denotes cardiac complications MESH:D005117
159 3225-3233 Species denotes patients Tax:9606
160 3357-3365 Species denotes patients Tax:9606
161 3600-3611 Species denotes coronavirus Tax:11118
162 3250-3258 Disease denotes COVID-19 MESH:C000657245
163 3287-3290 Disease denotes CVD MESH:D002318
164 3305-3326 Disease denotes cardiac complications MESH:D005117
165 3559-3567 Disease denotes COVID-19 MESH:C000657245
166 3639-3671 Disease denotes Middle-East Respiratory Syndrome MESH:D018352
167 3673-3677 Disease denotes MERS MESH:D018352