PMC:7102662 / 18863-19612 JSONTXT

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T164","span":{"begin":104,"end":112},"obj":"Disease"},{"id":"T165","span":{"begin":191,"end":199},"obj":"Disease"},{"id":"T166","span":{"begin":391,"end":399},"obj":"Disease"},{"id":"T167","span":{"begin":483,"end":491},"obj":"Disease"}],"attributes":[{"id":"A164","pred":"mondo_id","subj":"T164","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A165","pred":"mondo_id","subj":"T165","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A166","pred":"mondo_id","subj":"T166","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A167","pred":"mondo_id","subj":"T167","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"3 Summary and future directions\nAlthough respiratory illness is the dominant clinical manifestation of COVID-19, the shear burden of the illness implies that a large number of patients with COVID-19 would present with pre-existing CVD or develop new-onset cardiac dysfunction during the course of the illness. Considering this, the current understanding about the interplay between CVD and COVID-19 is grossly inadequate. It is therefore highly desirable that the future studies on COVID-19 specifically describe the incidence, mechanisms, clinical presentation and outcomes of various CV manifestations in these patients. The diagnostic and therapeutic challenges posed by the concurrence of these two illnesses also need to be adequately studied."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T109","span":{"begin":159,"end":160},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"3 Summary and future directions\nAlthough respiratory illness is the dominant clinical manifestation of COVID-19, the shear burden of the illness implies that a large number of patients with COVID-19 would present with pre-existing CVD or develop new-onset cardiac dysfunction during the course of the illness. Considering this, the current understanding about the interplay between CVD and COVID-19 is grossly inadequate. It is therefore highly desirable that the future studies on COVID-19 specifically describe the incidence, mechanisms, clinical presentation and outcomes of various CV manifestations in these patients. The diagnostic and therapeutic challenges posed by the concurrence of these two illnesses also need to be adequately studied."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T49","span":{"begin":42,"end":61},"obj":"Phenotype"}],"attributes":[{"id":"A49","pred":"hp_id","subj":"T49","obj":"http://purl.obolibrary.org/obo/HP_0002086"}],"text":"3 Summary and future directions\nAlthough respiratory illness is the dominant clinical manifestation of COVID-19, the shear burden of the illness implies that a large number of patients with COVID-19 would present with pre-existing CVD or develop new-onset cardiac dysfunction during the course of the illness. Considering this, the current understanding about the interplay between CVD and COVID-19 is grossly inadequate. It is therefore highly desirable that the future studies on COVID-19 specifically describe the incidence, mechanisms, clinical presentation and outcomes of various CV manifestations in these patients. The diagnostic and therapeutic challenges posed by the concurrence of these two illnesses also need to be adequately studied."}

{"project":"LitCovid-sentences","denotations":[{"id":"T154","span":{"begin":0,"end":32},"obj":"Sentence"},{"id":"T155","span":{"begin":33,"end":310},"obj":"Sentence"},{"id":"T156","span":{"begin":311,"end":422},"obj":"Sentence"},{"id":"T157","span":{"begin":423,"end":623},"obj":"Sentence"},{"id":"T158","span":{"begin":624,"end":749},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"3 Summary and future directions\nAlthough respiratory illness is the dominant clinical manifestation of COVID-19, the shear burden of the illness implies that a large number of patients with COVID-19 would present with pre-existing CVD or develop new-onset cardiac dysfunction during the course of the illness. Considering this, the current understanding about the interplay between CVD and COVID-19 is grossly inadequate. It is therefore highly desirable that the future studies on COVID-19 specifically describe the incidence, mechanisms, clinical presentation and outcomes of various CV manifestations in these patients. The diagnostic and therapeutic challenges posed by the concurrence of these two illnesses also need to be adequately studied."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T344","span":{"begin":42,"end":53},"obj":"UBERON:0001004"},{"id":"T345","span":{"begin":104,"end":112},"obj":"SP_7"},{"id":"T346","span":{"begin":191,"end":199},"obj":"SP_7"},{"id":"T347","span":{"begin":257,"end":264},"obj":"UBERON:0000948"},{"id":"T348","span":{"begin":391,"end":399},"obj":"SP_7"},{"id":"T349","span":{"begin":483,"end":491},"obj":"SP_7"},{"id":"T60649","span":{"begin":104,"end":112},"obj":"SP_7"},{"id":"T81322","span":{"begin":93,"end":101},"obj":"SP_7"},{"id":"T33054","span":{"begin":317,"end":325},"obj":"SP_7"},{"id":"T25561","span":{"begin":425,"end":433},"obj":"SP_7"},{"id":"T4488","span":{"begin":42,"end":53},"obj":"UBERON:0001004"},{"id":"T59575","span":{"begin":104,"end":112},"obj":"SP_7"},{"id":"T12110","span":{"begin":191,"end":199},"obj":"SP_7"},{"id":"T51515","span":{"begin":257,"end":264},"obj":"UBERON:0000948"},{"id":"T28958","span":{"begin":391,"end":399},"obj":"SP_7"},{"id":"T29729","span":{"begin":483,"end":491},"obj":"SP_7"}],"text":"3 Summary and future directions\nAlthough respiratory illness is the dominant clinical manifestation of COVID-19, the shear burden of the illness implies that a large number of patients with COVID-19 would present with pre-existing CVD or develop new-onset cardiac dysfunction during the course of the illness. Considering this, the current understanding about the interplay between CVD and COVID-19 is grossly inadequate. It is therefore highly desirable that the future studies on COVID-19 specifically describe the incidence, mechanisms, clinical presentation and outcomes of various CV manifestations in these patients. The diagnostic and therapeutic challenges posed by the concurrence of these two illnesses also need to be adequately studied."}

{"project":"LitCovid-PubTator","denotations":[{"id":"548","span":{"begin":177,"end":185},"obj":"Species"},{"id":"549","span":{"begin":614,"end":622},"obj":"Species"},{"id":"550","span":{"begin":42,"end":61},"obj":"Disease"},{"id":"551","span":{"begin":104,"end":112},"obj":"Disease"},{"id":"552","span":{"begin":191,"end":199},"obj":"Disease"},{"id":"553","span":{"begin":232,"end":235},"obj":"Disease"},{"id":"554","span":{"begin":257,"end":276},"obj":"Disease"},{"id":"555","span":{"begin":383,"end":386},"obj":"Disease"},{"id":"556","span":{"begin":391,"end":399},"obj":"Disease"},{"id":"557","span":{"begin":483,"end":491},"obj":"Disease"}],"attributes":[{"id":"A548","pred":"tao:has_database_id","subj":"548","obj":"Tax:9606"},{"id":"A549","pred":"tao:has_database_id","subj":"549","obj":"Tax:9606"},{"id":"A550","pred":"tao:has_database_id","subj":"550","obj":"MESH:D012140"},{"id":"A551","pred":"tao:has_database_id","subj":"551","obj":"MESH:C000657245"},{"id":"A552","pred":"tao:has_database_id","subj":"552","obj":"MESH:C000657245"},{"id":"A553","pred":"tao:has_database_id","subj":"553","obj":"MESH:D002318"},{"id":"A554","pred":"tao:has_database_id","subj":"554","obj":"MESH:D006331"},{"id":"A555","pred":"tao:has_database_id","subj":"555","obj":"MESH:D002318"},{"id":"A556","pred":"tao:has_database_id","subj":"556","obj":"MESH:C000657245"},{"id":"A557","pred":"tao:has_database_id","subj":"557","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"3 Summary and future directions\nAlthough respiratory illness is the dominant clinical manifestation of COVID-19, the shear burden of the illness implies that a large number of patients with COVID-19 would present with pre-existing CVD or develop new-onset cardiac dysfunction during the course of the illness. Considering this, the current understanding about the interplay between CVD and COVID-19 is grossly inadequate. It is therefore highly desirable that the future studies on COVID-19 specifically describe the incidence, mechanisms, clinical presentation and outcomes of various CV manifestations in these patients. The diagnostic and therapeutic challenges posed by the concurrence of these two illnesses also need to be adequately studied."}