PMC:7102662 / 17171-17988
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T41 | 203-210 | Body_part | denotes | tissues | http://purl.org/sig/ont/fma/fma9637 |
T42 | 225-239 | Body_part | denotes | cardiomyocytes | http://purl.org/sig/ont/fma/fma14067 |
T43 | 302-307 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T155 | 106-109 | Disease | denotes | ARB | http://purl.obolibrary.org/obo/MONDO_0012733 |
T156 | 130-138 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T157 | 252-260 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T158 | 361-369 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T159 | 466-469 | Disease | denotes | ARB | http://purl.obolibrary.org/obo/MONDO_0012733 |
T160 | 754-757 | Disease | denotes | ARB | http://purl.obolibrary.org/obo/MONDO_0012733 |
T161 | 800-808 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T104 | 6-9 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T105 | 15-16 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T106 | 225-239 | http://purl.obolibrary.org/obo/CL_0000746 | denotes | cardiomyocytes |
T107 | 296-307 | http://purl.obolibrary.org/obo/CLO_0053065 | denotes | human cells |
T108 | 318-319 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T24 | 49-63 | Chemical | denotes | ACE inhibitors | http://purl.obolibrary.org/obo/CHEBI_35457 |
T25 | 53-63 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
T26 | 65-69 | Chemical | denotes | ACEi | http://purl.obolibrary.org/obo/CHEBI_35457 |
T27 | 75-86 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
T28 | 461-465 | Chemical | denotes | ACEi | http://purl.obolibrary.org/obo/CHEBI_35457 |
T29 | 749-753 | Chemical | denotes | ACEi | http://purl.obolibrary.org/obo/CHEBI_35457 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T142 | 0-148 | Sentence | denotes | There has been a concern regarding the safety of ACE inhibitors (ACEi) and angiotensin receptor blockers (ARB) during the ongoing COVID-19 pandemic. |
T143 | 149-245 | Sentence | denotes | These agents upregulate expression of ACE2 in various tissues, including on cardiomyocytes [17]. |
T144 | 246-470 | Sentence | denotes | Since SARS-CoV-2 binds to ACE2 to gain entry into human cells, there is a potentially increased risk of developing COVID-19 or developing more severe disease in patients who are already on background treatment with ACEi/ARB. |
T145 | 471-561 | Sentence | denotes | However, to date, no experimental or clinical data have emerged to support these concerns. |
T146 | 562-638 | Sentence | denotes | At the same time, the risks of discontinuing these therapies are well known. |
T147 | 639-817 | Sentence | denotes | Therefore, several leading professional societies have strongly urged to not discontinue clinically-indicated ACEi/ARB therapy in the event the patient develops COVID-19 [18,19]. |
LitCovid-PMC-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T274 | 53-63 | CHEBI:35222;CHEBI:35222 | denotes | inhibitors |
T275 | 87-104 | CHEBI:48561;CHEBI:48561 | denotes | receptor blockers |
T276 | 130-138 | SP_7 | denotes | COVID-19 |
T277 | 173-183 | GO:0010467 | denotes | expression |
T278 | 187-191 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T279 | 203-210 | UBERON:0000479 | denotes | tissues |
T280 | 225-239 | CL:0000746 | denotes | cardiomyocytes |
T281 | 252-262 | SP_7 | denotes | SARS-CoV-2 |
T282 | 272-276 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T283 | 296-301 | SP_6;NCBITaxon:9606 | denotes | human |
T284 | 361-369 | SP_7 | denotes | COVID-19 |
T285 | 800-808 | SP_7 | denotes | COVID-19 |
T29868 | 24-29 | NCBITaxon:10239 | denotes | rega |
T44693 | 81-86 | SP_6;NCBITaxon:9606 | denotes | ensin |
T30153 | 87-92 | UBERON:0000948 | denotes | recep |
T84285 | 132-142 | UBERON:0002349 | denotes | VID-19 pan |
T53976 | 157-162 | NCBITaxon:10239 | denotes | ents |
T87440 | 225-235 | UBERON:0002349 | denotes | cardiomyoc |
T16635 | 250-258 | SP_7 | denotes | e SARS-C |
T1147 | 314-330 | UBERON:0002084 | denotes | is a potentiall |
T55144 | 360-376 | UBERON:0002084 | denotes | COVID-19 or dev |
T79081 | 481-486 | UBERON:0000948 | denotes | o dat |
T98834 | 498-506 | SP_7 | denotes | mental o |
T81730 | 521-526 | UBERON:0000948 | denotes | have |
T81536 | 588-592 | GO:0016265 | denotes | s of |
T85605 | 735-743 | SP_7 | denotes | lly-indi |
T316 | 53-63 | CHEBI:35222;CHEBI:35222 | denotes | inhibitors |
T317 | 87-104 | CHEBI:48561;CHEBI:48561 | denotes | receptor blockers |
T318 | 130-138 | SP_7 | denotes | COVID-19 |
T319 | 173-183 | GO:0010467 | denotes | expression |
T320 | 187-191 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T321 | 203-210 | UBERON:0000479 | denotes | tissues |
T322 | 225-239 | CL:0000746 | denotes | cardiomyocytes |
T323 | 252-262 | SP_7 | denotes | SARS-CoV-2 |
T324 | 272-276 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T325 | 296-301 | SP_6;NCBITaxon:9606 | denotes | human |
T326 | 361-369 | SP_7 | denotes | COVID-19 |
T327 | 800-808 | SP_7 | denotes | COVID-19 |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32247212-15897343-25241183 | 241-243 | 15897343 | denotes | 17 |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
498 | 49-52 | Gene | denotes | ACE | Gene:1636 |
499 | 187-191 | Gene | denotes | ACE2 | Gene:59272 |
500 | 272-276 | Gene | denotes | ACE2 | Gene:59272 |
501 | 252-262 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
502 | 296-301 | Species | denotes | human | Tax:9606 |
503 | 407-415 | Species | denotes | patients | Tax:9606 |
504 | 783-790 | Species | denotes | patient | Tax:9606 |
505 | 130-138 | Disease | denotes | COVID-19 | MESH:C000657245 |
506 | 361-369 | Disease | denotes | COVID-19 | MESH:C000657245 |
507 | 800-808 | Disease | denotes | COVID-19 | MESH:C000657245 |