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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T39 1435-1443 Body_part denotes troponin http://purl.org/sig/ont/fma/fma62338
T40 1844-1853 Body_part denotes troponins http://purl.org/sig/ont/fma/fma62338
T41 2609-2616 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T42 2631-2645 Body_part denotes cardiomyocytes http://purl.org/sig/ont/fma/fma14067
T43 2708-2713 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T144 63-71 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T145 172-180 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T146 430-438 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T147 733-741 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T148 892-900 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T149 1281-1289 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T150 1711-1720 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T151 2040-2048 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T152 2333-2341 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T153 2359-2401 Disease denotes ST-segment elevation myocardial infarction http://purl.obolibrary.org/obo/MONDO_0041656
T154 2380-2401 Disease denotes myocardial infarction http://purl.obolibrary.org/obo/MONDO_0005068
T155 2512-2515 Disease denotes ARB http://purl.obolibrary.org/obo/MONDO_0012733
T156 2536-2544 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T157 2658-2666 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T158 2767-2775 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T159 2872-2875 Disease denotes ARB http://purl.obolibrary.org/obo/MONDO_0012733
T160 3160-3163 Disease denotes ARB http://purl.obolibrary.org/obo/MONDO_0012733
T161 3206-3214 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T162 3368-3383 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T163 3374-3383 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T95 201-202 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T96 527-537 http://purl.obolibrary.org/obo/CLO_0002807 denotes in donning
T97 1415-1420 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T98 1757-1760 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T99 1870-1878 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T100 2091-2094 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T101 2107-2108 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T102 2359-2361 http://purl.obolibrary.org/obo/CLO_0009141 denotes ST
T103 2359-2361 http://purl.obolibrary.org/obo/CLO_0050980 denotes ST
T104 2412-2415 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T105 2421-2422 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T106 2631-2645 http://purl.obolibrary.org/obo/CL_0000746 denotes cardiomyocytes
T107 2702-2713 http://purl.obolibrary.org/obo/CLO_0053065 denotes human cells
T108 2724-2725 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T22 1870-1878 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T23 2359-2361 Chemical denotes ST http://purl.obolibrary.org/obo/CHEBI_141393
T24 2455-2469 Chemical denotes ACE inhibitors http://purl.obolibrary.org/obo/CHEBI_35457
T25 2459-2469 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T26 2471-2475 Chemical denotes ACEi http://purl.obolibrary.org/obo/CHEBI_35457
T27 2481-2492 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T28 2867-2871 Chemical denotes ACEi http://purl.obolibrary.org/obo/CHEBI_35457
T29 3155-3159 Chemical denotes ACEi http://purl.obolibrary.org/obo/CHEBI_35457
T30 3423-3428 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T31 3472-3477 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T32 3562-3573 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T33 3574-3592 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T34 3597-3609 Chemical denotes azathioprine http://purl.obolibrary.org/obo/CHEBI_2948
T35 3710-3715 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T36 3868-3879 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T37 3880-3898 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T38 4053-4057 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T45 2359-2379 Phenotype denotes ST-segment elevation http://purl.obolibrary.org/obo/HP_0012251
T46 2380-2401 Phenotype denotes myocardial infarction http://purl.obolibrary.org/obo/HP_0001658
T47 3729-3748 Phenotype denotes prolong QT interval http://purl.obolibrary.org/obo/HP_0001657
T48 4076-4095 Phenotype denotes prolong QT interval http://purl.obolibrary.org/obo/HP_0001657

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T22 2303-2315 http://purl.obolibrary.org/obo/GO_0042730 denotes fibrinolysis
T23 3368-3383 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T122 0-181 Sentence denotes The overall management principles for patients presenting with COVID-19 who develop CV complications or who have pre-existing CVD are same as for any other patient without COVID-19.
T123 182-250 Sentence denotes However, there are a few important points that need consideration-1.
T124 251-371 Sentence denotes As caregivers, it is our utmost responsibility to protect ourselves from getting infected while managing these patients.
T125 372-496 Sentence denotes Therefore, all heathcare personnel engaged in the care of COVID-19 patients must observe necessary precautions at all times.
T126 497-647 Sentence denotes All of them should be trained in donning, usage, and doffing of the personal protective equipment in accordance with the existing practice guidelines.
T127 648-650 Sentence denotes 2.
T128 651-811 Sentence denotes The hospital systems need to ensure preparedness for dealing with large volume of COVID-19 patients, many of whom would need ICU care and/or acute cardiac care.
T129 812-971 Sentence denotes Appropriate protocols for rapid diagnosis, triage, isolation, and management of COVID-19 patients with CV complications should be developed and well-rehearsed.
T130 972-1140 Sentence denotes Rapid triaging and management of these patients is crucial, not only to allow efficient utilization of healthcare resources but also to minimize exposure to caregivers.
T131 1141-1295 Sentence denotes There are already reports highlighting delays in delivering acute cardiac care due to extra precautions that need to be observed in view of COVID-19 [14].
T132 1296-1343 Sentence denotes Efforts should be made to minimize such delays.
T133 1344-1346 Sentence denotes 3.
T134 1347-1487 Sentence denotes Strong emphasis should be placed on avoiding unwarranted diagnostic tests (e.g. cardiac troponin, echocardiography, etc.) in these patients.
T135 1488-1721 Sentence denotes This is required to minimize unwarranted downstream diagnostic/therapeutic procedures which would further strain the already stretched healthcare resources and would also subject caregivers to added risk of exposure to the infection.
T136 1722-1884 Sentence denotes The American College of Cardiology has released an advisory discouraging random measurement of cardiac biomarkers such as troponins and natriuretic peptides [15].
T137 1885-2049 Sentence denotes It urges all the clinicians to reserve these assays for circumstances in which they would actually meaningfully add to the management of the patients with COVID-19.
T138 2050-2187 Sentence denotes The American Society of Echocardiography has also issued a similar advisory regarding the use of echocardiography in these patients [16].
T139 2188-2190 Sentence denotes 4.
T140 2191-2402 Sentence denotes The individual hospitals may also have to reconsider risk-benefit ratio of primary percutaneous intervention vs fibrinolysis in patients with COVID-19 who present with ST-segment elevation myocardial infarction.
T141 2403-2405 Sentence denotes 5.
T142 2406-2554 Sentence denotes There has been a concern regarding the safety of ACE inhibitors (ACEi) and angiotensin receptor blockers (ARB) during the ongoing COVID-19 pandemic.
T143 2555-2651 Sentence denotes These agents upregulate expression of ACE2 in various tissues, including on cardiomyocytes [17].
T144 2652-2876 Sentence denotes Since SARS-CoV-2 binds to ACE2 to gain entry into human cells, there is a potentially increased risk of developing COVID-19 or developing more severe disease in patients who are already on background treatment with ACEi/ARB.
T145 2877-2967 Sentence denotes However, to date, no experimental or clinical data have emerged to support these concerns.
T146 2968-3044 Sentence denotes At the same time, the risks of discontinuing these therapies are well known.
T147 3045-3223 Sentence denotes Therefore, several leading professional societies have strongly urged to not discontinue clinically-indicated ACEi/ARB therapy in the event the patient develops COVID-19 [18,19].
T148 3224-3226 Sentence denotes 6.
T149 3227-3384 Sentence denotes Clinicians caring for these patients also need to be fully aware of the potential CV side-effects of various therapies used for treating the viral infection.
T150 3385-3546 Sentence denotes Additionally, various anti-retroviral drugs have significant interactions with cardiac drugs, which need to be considered and appropriate dose modification done.
T151 3547-3698 Sentence denotes More recently, chloroquine/hydroxychloroquine and azathioprine have been proposed as potential therapeutic options, based on preliminary evidence [20].
T152 3699-3813 Sentence denotes Both these drugs are known to prolong QT interval and due caution must be exercised when prescribing these agents.
T153 3814-4096 Sentence denotes Their combination is best avoided and even when using chloroquine/hydroxychloroquine alone, daily electrocardiogram for monitoring QT interval is warranted, esp. in patients with hepatic or renal dysfunction and in those receiving another drug with potential to prolong QT interval.

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T258 63-71 SP_7 denotes COVID-19
T259 172-180 SP_7 denotes COVID-19
T260 430-438 SP_7 denotes COVID-19
T261 733-741 SP_7 denotes COVID-19
T262 798-805 UBERON:0000948 denotes cardiac
T263 892-900 SP_7 denotes COVID-19
T264 1190-1200 GO:0007567 denotes delivering
T265 1207-1214 UBERON:0000948 denotes cardiac
T266 1281-1289 SP_7 denotes COVID-19
T267 1427-1434 UBERON:0000948 denotes cardiac
T268 1746-1756 UBERON:0000948 denotes Cardiology
T269 1817-1824 UBERON:0000948 denotes cardiac
T270 2040-2048 SP_7 denotes COVID-19
T271 2303-2315 GO:0042730 denotes fibrinolysis
T272 2333-2341 SP_7 denotes COVID-19
T273 2380-2390 UBERON:0002349 denotes myocardial
T274 2459-2469 CHEBI:35222;CHEBI:35222 denotes inhibitors
T275 2493-2510 CHEBI:48561;CHEBI:48561 denotes receptor blockers
T276 2536-2544 SP_7 denotes COVID-19
T277 2579-2589 GO:0010467 denotes expression
T278 2593-2597 G_3;PG_10;PR:000003622 denotes ACE2
T279 2609-2616 UBERON:0000479 denotes tissues
T280 2631-2645 CL:0000746 denotes cardiomyocytes
T281 2658-2668 SP_7 denotes SARS-CoV-2
T282 2678-2682 G_3;PG_10;PR:000003622 denotes ACE2
T283 2702-2707 SP_6;NCBITaxon:9606 denotes human
T284 2767-2775 SP_7 denotes COVID-19
T285 3206-3214 SP_7 denotes COVID-19
T286 3368-3373 NCBITaxon:10239 denotes viral
T287 3407-3412 CHEBI:67079;CHEBI:67079 denotes anti-
T288 3412-3422 NCBITaxon:11632 denotes retroviral
T289 3423-3428 CHEBI:23888;CHEBI:23888 denotes drugs
T290 3464-3471 UBERON:0000948 denotes cardiac
T291 3472-3477 CHEBI:23888;CHEBI:23888 denotes drugs
T292 3562-3573 CHEBI:3638;DG_10;CHEBI:3638 denotes chloroquine
T293 3574-3592 CHEBI:5801;DG_20;CHEBI:5801 denotes hydroxychloroquine
T294 3597-3609 CHEBI:2948;CHEBI:2948 denotes azathioprine
T295 3710-3715 CHEBI:23888;CHEBI:23888 denotes drugs
T296 3806-3812 CHEBI:23888;CHEBI:23888 denotes agents
T297 3868-3879 CHEBI:3638;DG_10;CHEBI:3638 denotes chloroquine
T298 3880-3898 CHEBI:5801;DG_20;CHEBI:5801 denotes hydroxychloroquine
T299 3993-4000 UBERON:0002107 denotes hepatic
T300 4004-4009 UBERON:0002113 denotes renal
T301 4053-4057 CHEBI:23888;CHEBI:23888 denotes drug
T44699 212-217 UBERON:0000948 denotes tant
T13321 242-249 UBERON:0000948 denotes ation-1
T1958 308-312 GO:0016265 denotes our
T10093 387-393 GO:0016265 denotes heathc
T26141 557-571 UBERON:0004535 denotes of the person
T57516 590-598 SP_7 denotes ment in
T16826 611-622 UBERON:0002349 denotes th the exis
T31833 636-646 UBERON:0002349 denotes guidelines
T58582 705-713 SP_7 denotes ealing w
T94661 785-795 UBERON:0002349 denotes and/or acu
T87705 822-829 UBERON:0000948 denotes e proto
T48656 958-965 UBERON:0000948 denotes ll-rehe
T7641 1105-1112 UBERON:0000948 denotes to mini
T19884 1322-1329 UBERON:0000948 denotes minimiz
T28710 1421-1426 GO:0016265 denotes (e.g.
T28698 1542-1549 UBERON:0000948 denotes agnosti
T59720 1644-1652 SP_7 denotes and woul
T39589 1976-1983 UBERON:0000948 denotes ctually
T43336 2003-2010 UBERON:0000948 denotes the ma
T74507 2038-2046 SP_7 denotes h COVID-
T87124 2140-2148 UBERON:0001621 denotes use of e
T70670 2150-2160 UBERON:0002349 denotes ocardiogra
T13529 2175-2180 NCBITaxon:10239 denotes tient
T86273 2355-2359 GO:0016265 denotes ith
T62094 2367-2371 SP_10 denotes nt e
T86471 2391-2395 SP_10 denotes infa
T29868 2430-2435 NCBITaxon:10239 denotes rega
T44693 2487-2492 SP_6;NCBITaxon:9606 denotes ensin
T30153 2493-2498 UBERON:0000948 denotes recep
T84285 2538-2548 UBERON:0002349 denotes VID-19 pan
T53976 2563-2568 NCBITaxon:10239 denotes ents
T87440 2631-2641 UBERON:0002349 denotes cardiomyoc
T16635 2656-2664 SP_7 denotes e SARS-C
T1147 2720-2736 UBERON:0002084 denotes is a potentiall
T55144 2766-2782 UBERON:0002084 denotes COVID-19 or dev
T79081 2887-2892 UBERON:0000948 denotes o dat
T98834 2904-2912 SP_7 denotes mental o
T81730 2927-2932 UBERON:0000948 denotes have
T81536 2994-2998 GO:0016265 denotes s of
T85605 3141-3149 SP_7 denotes lly-indi
T35536 3227-3235 SP_7 denotes Clinicia
T14057 3489-3497 SP_7 denotes to be c
T37740 3652-3660 CHEBI:33695;CHEBI:33695;SO:0000673 denotes c option
T78714 3707-3711 SP_10 denotes se d
T37413 3723-3731 SP_10 denotes wn to pr
T33567 3775-3785 SP_7 denotes ercised wh
T76508 3846-3850 SP_10 denotes d an
T48944 3890-3894 CHEBI:18059;CHEBI:18059;GO:0006629 denotes oroq
T57411 3895-3903 GO:0006629 denotes ine alon
T94539 3976-3983 CHEBI:17234;CHEBI:17234;GO:0006006 denotes in pati
T59989 3984-3992 GO:0006006 denotes nts with
T68492 18-29 CHEBI:3638;DG_10;CHEBI:3638 denotes ment princi
T72351 30-48 CHEBI:5801;DG_20;CHEBI:5801 denotes les for patients p
T96108 144-151 UBERON:0002107 denotes r any o
T69138 155-160 UBERON:0002113 denotes pati
T30274 204-208 CHEBI:23888;CHEBI:23888 denotes ew i
T302 430-438 SP_7 denotes COVID-19
T303 733-741 SP_7 denotes COVID-19
T304 798-805 UBERON:0000948 denotes cardiac
T305 892-900 SP_7 denotes COVID-19
T306 1190-1200 GO:0007567 denotes delivering
T307 1207-1214 UBERON:0000948 denotes cardiac
T308 1281-1289 SP_7 denotes COVID-19
T309 1427-1434 UBERON:0000948 denotes cardiac
T310 1746-1756 UBERON:0000948 denotes Cardiology
T311 1817-1824 UBERON:0000948 denotes cardiac
T312 2040-2048 SP_7 denotes COVID-19
T313 2303-2315 GO:0042730 denotes fibrinolysis
T314 2333-2341 SP_7 denotes COVID-19
T315 2380-2390 UBERON:0002349 denotes myocardial
T316 2459-2469 CHEBI:35222;CHEBI:35222 denotes inhibitors
T317 2493-2510 CHEBI:48561;CHEBI:48561 denotes receptor blockers
T318 2536-2544 SP_7 denotes COVID-19
T319 2579-2589 GO:0010467 denotes expression
T320 2593-2597 G_3;PG_10;PR:000003622 denotes ACE2
T321 2609-2616 UBERON:0000479 denotes tissues
T322 2631-2645 CL:0000746 denotes cardiomyocytes
T323 2658-2668 SP_7 denotes SARS-CoV-2
T324 2678-2682 G_3;PG_10;PR:000003622 denotes ACE2
T325 2702-2707 SP_6;NCBITaxon:9606 denotes human
T326 2767-2775 SP_7 denotes COVID-19
T327 3206-3214 SP_7 denotes COVID-19
T328 3368-3373 NCBITaxon:10239 denotes viral
T329 3407-3412 CHEBI:67079;CHEBI:67079 denotes anti-
T330 3412-3422 NCBITaxon:11632 denotes retroviral
T331 3423-3428 CHEBI:23888;CHEBI:23888 denotes drugs
T332 3464-3471 UBERON:0000948 denotes cardiac
T333 3472-3477 CHEBI:23888;CHEBI:23888 denotes drugs
T334 3562-3573 CHEBI:3638;DG_10;CHEBI:3638 denotes chloroquine
T335 3574-3592 CHEBI:5801;DG_20;CHEBI:5801 denotes hydroxychloroquine
T336 3597-3609 CHEBI:2948;CHEBI:2948 denotes azathioprine
T337 3710-3715 CHEBI:23888;CHEBI:23888 denotes drugs
T338 3806-3812 CHEBI:23888;CHEBI:23888 denotes agents
T339 3868-3879 CHEBI:3638;DG_10;CHEBI:3638 denotes chloroquine
T340 3880-3898 CHEBI:5801;DG_20;CHEBI:5801 denotes hydroxychloroquine
T341 3993-4000 UBERON:0002107 denotes hepatic
T342 4004-4009 UBERON:0002113 denotes renal
T343 4053-4057 CHEBI:23888;CHEBI:23888 denotes drug

2_test

Id Subject Object Predicate Lexical cue
32247212-15897343-25241183 2647-2649 15897343 denotes 17

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
456 362-370 Species denotes patients Tax:9606
457 439-447 Species denotes patients Tax:9606
458 332-340 Disease denotes infected MESH:D007239
459 430-438 Disease denotes COVID-19 MESH:C000657245
466 742-750 Species denotes patients Tax:9606
467 901-909 Species denotes patients Tax:9606
468 1011-1019 Species denotes patients Tax:9606
469 733-741 Disease denotes COVID-19 MESH:C000657245
470 892-900 Disease denotes COVID-19 MESH:C000657245
471 1281-1289 Disease denotes COVID-19 MESH:C000657245
477 1478-1486 Species denotes patients Tax:9606
478 2026-2034 Species denotes patients Tax:9606
479 2173-2181 Species denotes patients Tax:9606
480 1711-1720 Disease denotes infection MESH:D007239
481 2040-2048 Disease denotes COVID-19 MESH:C000657245
485 2319-2327 Species denotes patients Tax:9606
486 2333-2341 Disease denotes COVID-19 MESH:C000657245
487 2380-2401 Disease denotes myocardial infarction MESH:D009203
498 2455-2458 Gene denotes ACE Gene:1636
499 2593-2597 Gene denotes ACE2 Gene:59272
500 2678-2682 Gene denotes ACE2 Gene:59272
501 2658-2668 Species denotes SARS-CoV-2 Tax:2697049
502 2702-2707 Species denotes human Tax:9606
503 2813-2821 Species denotes patients Tax:9606
504 3189-3196 Species denotes patient Tax:9606
505 2536-2544 Disease denotes COVID-19 MESH:C000657245
506 2767-2775 Disease denotes COVID-19 MESH:C000657245
507 3206-3214 Disease denotes COVID-19 MESH:C000657245
518 3971-3974 Gene denotes esp Gene:148713
519 3255-3263 Species denotes patients Tax:9606
520 3979-3987 Species denotes patients Tax:9606
521 3562-3573 Chemical denotes chloroquine MESH:D002738
522 3574-3592 Chemical denotes hydroxychloroquine MESH:D006886
523 3597-3609 Chemical denotes azathioprine MESH:D001379
524 3868-3879 Chemical denotes chloroquine MESH:D002738
525 3880-3898 Chemical denotes hydroxychloroquine MESH:D006886
526 3368-3383 Disease denotes viral infection MESH:D001102
527 3993-4021 Disease denotes hepatic or renal dysfunction MESH:D008107
533 38-46 Species denotes patients Tax:9606
534 156-163 Species denotes patient Tax:9606
535 63-71 Disease denotes COVID-19 MESH:C000657245
536 126-129 Disease denotes CVD MESH:D002318
537 172-180 Disease denotes COVID-19 MESH:C000657245