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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T39 1464-1472 Body_part denotes troponin http://purl.org/sig/ont/fma/fma62338
T40 1873-1882 Body_part denotes troponins http://purl.org/sig/ont/fma/fma62338
T41 2638-2645 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T42 2660-2674 Body_part denotes cardiomyocytes http://purl.org/sig/ont/fma/fma14067
T43 2737-2742 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T144 92-100 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T145 201-209 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T146 459-467 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T147 762-770 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T148 921-929 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T149 1310-1318 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T150 1740-1749 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T151 2069-2077 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T152 2362-2370 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T153 2388-2430 Disease denotes ST-segment elevation myocardial infarction http://purl.obolibrary.org/obo/MONDO_0041656
T154 2409-2430 Disease denotes myocardial infarction http://purl.obolibrary.org/obo/MONDO_0005068
T155 2541-2544 Disease denotes ARB http://purl.obolibrary.org/obo/MONDO_0012733
T156 2565-2573 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T157 2687-2695 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T158 2796-2804 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T159 2901-2904 Disease denotes ARB http://purl.obolibrary.org/obo/MONDO_0012733
T160 3189-3192 Disease denotes ARB http://purl.obolibrary.org/obo/MONDO_0012733
T161 3235-3243 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T162 3397-3412 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T163 3403-3412 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T95 230-231 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T96 556-566 http://purl.obolibrary.org/obo/CLO_0002807 denotes in donning
T97 1444-1449 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T98 1786-1789 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T99 1899-1907 http://purl.obolibrary.org/obo/PR_000018263 denotes peptides
T100 2120-2123 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T101 2136-2137 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T102 2388-2390 http://purl.obolibrary.org/obo/CLO_0009141 denotes ST
T103 2388-2390 http://purl.obolibrary.org/obo/CLO_0050980 denotes ST
T104 2441-2444 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T105 2450-2451 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T106 2660-2674 http://purl.obolibrary.org/obo/CL_0000746 denotes cardiomyocytes
T107 2731-2742 http://purl.obolibrary.org/obo/CLO_0053065 denotes human cells
T108 2753-2754 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T22 1899-1907 Chemical denotes peptides http://purl.obolibrary.org/obo/CHEBI_16670
T23 2388-2390 Chemical denotes ST http://purl.obolibrary.org/obo/CHEBI_141393
T24 2484-2498 Chemical denotes ACE inhibitors http://purl.obolibrary.org/obo/CHEBI_35457
T25 2488-2498 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T26 2500-2504 Chemical denotes ACEi http://purl.obolibrary.org/obo/CHEBI_35457
T27 2510-2521 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T28 2896-2900 Chemical denotes ACEi http://purl.obolibrary.org/obo/CHEBI_35457
T29 3184-3188 Chemical denotes ACEi http://purl.obolibrary.org/obo/CHEBI_35457
T30 3452-3457 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T31 3501-3506 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T32 3591-3602 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T33 3603-3621 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T34 3626-3638 Chemical denotes azathioprine http://purl.obolibrary.org/obo/CHEBI_2948
T35 3739-3744 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T36 3897-3908 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T37 3909-3927 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T38 4082-4086 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T45 2388-2408 Phenotype denotes ST-segment elevation http://purl.obolibrary.org/obo/HP_0012251
T46 2409-2430 Phenotype denotes myocardial infarction http://purl.obolibrary.org/obo/HP_0001658
T47 3758-3777 Phenotype denotes prolong QT interval http://purl.obolibrary.org/obo/HP_0001657
T48 4105-4124 Phenotype denotes prolong QT interval http://purl.obolibrary.org/obo/HP_0001657

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T22 2332-2344 http://purl.obolibrary.org/obo/GO_0042730 denotes fibrinolysis
T23 3397-3412 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T121 0-28 Sentence denotes 2.3 Management implications
T122 29-210 Sentence denotes The overall management principles for patients presenting with COVID-19 who develop CV complications or who have pre-existing CVD are same as for any other patient without COVID-19.
T123 211-279 Sentence denotes However, there are a few important points that need consideration-1.
T124 280-400 Sentence denotes As caregivers, it is our utmost responsibility to protect ourselves from getting infected while managing these patients.
T125 401-525 Sentence denotes Therefore, all heathcare personnel engaged in the care of COVID-19 patients must observe necessary precautions at all times.
T126 526-676 Sentence denotes All of them should be trained in donning, usage, and doffing of the personal protective equipment in accordance with the existing practice guidelines.
T127 677-679 Sentence denotes 2.
T128 680-840 Sentence denotes The hospital systems need to ensure preparedness for dealing with large volume of COVID-19 patients, many of whom would need ICU care and/or acute cardiac care.
T129 841-1000 Sentence denotes Appropriate protocols for rapid diagnosis, triage, isolation, and management of COVID-19 patients with CV complications should be developed and well-rehearsed.
T130 1001-1169 Sentence denotes Rapid triaging and management of these patients is crucial, not only to allow efficient utilization of healthcare resources but also to minimize exposure to caregivers.
T131 1170-1324 Sentence denotes There are already reports highlighting delays in delivering acute cardiac care due to extra precautions that need to be observed in view of COVID-19 [14].
T132 1325-1372 Sentence denotes Efforts should be made to minimize such delays.
T133 1373-1375 Sentence denotes 3.
T134 1376-1516 Sentence denotes Strong emphasis should be placed on avoiding unwarranted diagnostic tests (e.g. cardiac troponin, echocardiography, etc.) in these patients.
T135 1517-1750 Sentence denotes This is required to minimize unwarranted downstream diagnostic/therapeutic procedures which would further strain the already stretched healthcare resources and would also subject caregivers to added risk of exposure to the infection.
T136 1751-1913 Sentence denotes The American College of Cardiology has released an advisory discouraging random measurement of cardiac biomarkers such as troponins and natriuretic peptides [15].
T137 1914-2078 Sentence denotes It urges all the clinicians to reserve these assays for circumstances in which they would actually meaningfully add to the management of the patients with COVID-19.
T138 2079-2216 Sentence denotes The American Society of Echocardiography has also issued a similar advisory regarding the use of echocardiography in these patients [16].
T139 2217-2219 Sentence denotes 4.
T140 2220-2431 Sentence denotes The individual hospitals may also have to reconsider risk-benefit ratio of primary percutaneous intervention vs fibrinolysis in patients with COVID-19 who present with ST-segment elevation myocardial infarction.
T141 2432-2434 Sentence denotes 5.
T142 2435-2583 Sentence denotes There has been a concern regarding the safety of ACE inhibitors (ACEi) and angiotensin receptor blockers (ARB) during the ongoing COVID-19 pandemic.
T143 2584-2680 Sentence denotes These agents upregulate expression of ACE2 in various tissues, including on cardiomyocytes [17].
T144 2681-2905 Sentence denotes Since SARS-CoV-2 binds to ACE2 to gain entry into human cells, there is a potentially increased risk of developing COVID-19 or developing more severe disease in patients who are already on background treatment with ACEi/ARB.
T145 2906-2996 Sentence denotes However, to date, no experimental or clinical data have emerged to support these concerns.
T146 2997-3073 Sentence denotes At the same time, the risks of discontinuing these therapies are well known.
T147 3074-3252 Sentence denotes Therefore, several leading professional societies have strongly urged to not discontinue clinically-indicated ACEi/ARB therapy in the event the patient develops COVID-19 [18,19].
T148 3253-3255 Sentence denotes 6.
T149 3256-3413 Sentence denotes Clinicians caring for these patients also need to be fully aware of the potential CV side-effects of various therapies used for treating the viral infection.
T150 3414-3575 Sentence denotes Additionally, various anti-retroviral drugs have significant interactions with cardiac drugs, which need to be considered and appropriate dose modification done.
T151 3576-3727 Sentence denotes More recently, chloroquine/hydroxychloroquine and azathioprine have been proposed as potential therapeutic options, based on preliminary evidence [20].
T152 3728-3842 Sentence denotes Both these drugs are known to prolong QT interval and due caution must be exercised when prescribing these agents.
T153 3843-4125 Sentence denotes Their combination is best avoided and even when using chloroquine/hydroxychloroquine alone, daily electrocardiogram for monitoring QT interval is warranted, esp. in patients with hepatic or renal dysfunction and in those receiving another drug with potential to prolong QT interval.

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T258 92-100 SP_7 denotes COVID-19
T259 201-209 SP_7 denotes COVID-19
T260 459-467 SP_7 denotes COVID-19
T261 762-770 SP_7 denotes COVID-19
T262 827-834 UBERON:0000948 denotes cardiac
T263 921-929 SP_7 denotes COVID-19
T264 1219-1229 GO:0007567 denotes delivering
T265 1236-1243 UBERON:0000948 denotes cardiac
T266 1310-1318 SP_7 denotes COVID-19
T267 1456-1463 UBERON:0000948 denotes cardiac
T268 1775-1785 UBERON:0000948 denotes Cardiology
T269 1846-1853 UBERON:0000948 denotes cardiac
T270 2069-2077 SP_7 denotes COVID-19
T271 2332-2344 GO:0042730 denotes fibrinolysis
T272 2362-2370 SP_7 denotes COVID-19
T273 2409-2419 UBERON:0002349 denotes myocardial
T274 2488-2498 CHEBI:35222;CHEBI:35222 denotes inhibitors
T275 2522-2539 CHEBI:48561;CHEBI:48561 denotes receptor blockers
T276 2565-2573 SP_7 denotes COVID-19
T277 2608-2618 GO:0010467 denotes expression
T278 2622-2626 G_3;PG_10;PR:000003622 denotes ACE2
T279 2638-2645 UBERON:0000479 denotes tissues
T280 2660-2674 CL:0000746 denotes cardiomyocytes
T281 2687-2697 SP_7 denotes SARS-CoV-2
T282 2707-2711 G_3;PG_10;PR:000003622 denotes ACE2
T283 2731-2736 SP_6;NCBITaxon:9606 denotes human
T284 2796-2804 SP_7 denotes COVID-19
T285 3235-3243 SP_7 denotes COVID-19
T286 3397-3402 NCBITaxon:10239 denotes viral
T287 3436-3441 CHEBI:67079;CHEBI:67079 denotes anti-
T288 3441-3451 NCBITaxon:11632 denotes retroviral
T289 3452-3457 CHEBI:23888;CHEBI:23888 denotes drugs
T290 3493-3500 UBERON:0000948 denotes cardiac
T291 3501-3506 CHEBI:23888;CHEBI:23888 denotes drugs
T292 3591-3602 CHEBI:3638;DG_10;CHEBI:3638 denotes chloroquine
T293 3603-3621 CHEBI:5801;DG_20;CHEBI:5801 denotes hydroxychloroquine
T294 3626-3638 CHEBI:2948;CHEBI:2948 denotes azathioprine
T295 3739-3744 CHEBI:23888;CHEBI:23888 denotes drugs
T296 3835-3841 CHEBI:23888;CHEBI:23888 denotes agents
T297 3897-3908 CHEBI:3638;DG_10;CHEBI:3638 denotes chloroquine
T298 3909-3927 CHEBI:5801;DG_20;CHEBI:5801 denotes hydroxychloroquine
T299 4022-4029 UBERON:0002107 denotes hepatic
T300 4033-4038 UBERON:0002113 denotes renal
T301 4082-4086 CHEBI:23888;CHEBI:23888 denotes drug
T44699 241-246 UBERON:0000948 denotes tant
T13321 271-278 UBERON:0000948 denotes ation-1
T1958 337-341 GO:0016265 denotes our
T10093 416-422 GO:0016265 denotes heathc
T26141 586-600 UBERON:0004535 denotes of the person
T57516 619-627 SP_7 denotes ment in
T16826 640-651 UBERON:0002349 denotes th the exis
T31833 665-675 UBERON:0002349 denotes guidelines
T58582 734-742 SP_7 denotes ealing w
T94661 814-824 UBERON:0002349 denotes and/or acu
T87705 851-858 UBERON:0000948 denotes e proto
T48656 987-994 UBERON:0000948 denotes ll-rehe
T7641 1134-1141 UBERON:0000948 denotes to mini
T19884 1351-1358 UBERON:0000948 denotes minimiz
T28710 1450-1455 GO:0016265 denotes (e.g.
T28698 1571-1578 UBERON:0000948 denotes agnosti
T59720 1673-1681 SP_7 denotes and woul
T39589 2005-2012 UBERON:0000948 denotes ctually
T43336 2032-2039 UBERON:0000948 denotes the ma
T74507 2067-2075 SP_7 denotes h COVID-
T87124 2169-2177 UBERON:0001621 denotes use of e
T70670 2179-2189 UBERON:0002349 denotes ocardiogra
T13529 2204-2209 NCBITaxon:10239 denotes tient
T86273 2384-2388 GO:0016265 denotes ith
T62094 2396-2400 SP_10 denotes nt e
T86471 2420-2424 SP_10 denotes infa
T29868 2459-2464 NCBITaxon:10239 denotes rega
T44693 2516-2521 SP_6;NCBITaxon:9606 denotes ensin
T30153 2522-2527 UBERON:0000948 denotes recep
T84285 2567-2577 UBERON:0002349 denotes VID-19 pan
T53976 2592-2597 NCBITaxon:10239 denotes ents
T87440 2660-2670 UBERON:0002349 denotes cardiomyoc
T16635 2685-2693 SP_7 denotes e SARS-C
T1147 2749-2765 UBERON:0002084 denotes is a potentiall
T55144 2795-2811 UBERON:0002084 denotes COVID-19 or dev
T79081 2916-2921 UBERON:0000948 denotes o dat
T98834 2933-2941 SP_7 denotes mental o
T81730 2956-2961 UBERON:0000948 denotes have
T81536 3023-3027 GO:0016265 denotes s of
T85605 3170-3178 SP_7 denotes lly-indi
T35536 3256-3264 SP_7 denotes Clinicia
T14057 3518-3526 SP_7 denotes to be c
T37740 3681-3689 CHEBI:33695;CHEBI:33695;SO:0000673 denotes c option
T78714 3736-3740 SP_10 denotes se d
T37413 3752-3760 SP_10 denotes wn to pr
T33567 3804-3814 SP_7 denotes ercised wh
T76508 3875-3879 SP_10 denotes d an
T48944 3919-3923 CHEBI:18059;CHEBI:18059;GO:0006629 denotes oroq
T57411 3924-3932 GO:0006629 denotes ine alon
T94539 4005-4012 CHEBI:17234;CHEBI:17234;GO:0006006 denotes in pati
T59989 4013-4021 GO:0006006 denotes nts with
T68492 47-58 CHEBI:3638;DG_10;CHEBI:3638 denotes ment princi
T72351 59-77 CHEBI:5801;DG_20;CHEBI:5801 denotes les for patients p
T96108 173-180 UBERON:0002107 denotes r any o
T69138 184-189 UBERON:0002113 denotes pati
T30274 233-237 CHEBI:23888;CHEBI:23888 denotes ew i
T302 459-467 SP_7 denotes COVID-19
T303 762-770 SP_7 denotes COVID-19
T304 827-834 UBERON:0000948 denotes cardiac
T305 921-929 SP_7 denotes COVID-19
T306 1219-1229 GO:0007567 denotes delivering
T307 1236-1243 UBERON:0000948 denotes cardiac
T308 1310-1318 SP_7 denotes COVID-19
T309 1456-1463 UBERON:0000948 denotes cardiac
T310 1775-1785 UBERON:0000948 denotes Cardiology
T311 1846-1853 UBERON:0000948 denotes cardiac
T312 2069-2077 SP_7 denotes COVID-19
T313 2332-2344 GO:0042730 denotes fibrinolysis
T314 2362-2370 SP_7 denotes COVID-19
T315 2409-2419 UBERON:0002349 denotes myocardial
T316 2488-2498 CHEBI:35222;CHEBI:35222 denotes inhibitors
T317 2522-2539 CHEBI:48561;CHEBI:48561 denotes receptor blockers
T318 2565-2573 SP_7 denotes COVID-19
T319 2608-2618 GO:0010467 denotes expression
T320 2622-2626 G_3;PG_10;PR:000003622 denotes ACE2
T321 2638-2645 UBERON:0000479 denotes tissues
T322 2660-2674 CL:0000746 denotes cardiomyocytes
T323 2687-2697 SP_7 denotes SARS-CoV-2
T324 2707-2711 G_3;PG_10;PR:000003622 denotes ACE2
T325 2731-2736 SP_6;NCBITaxon:9606 denotes human
T326 2796-2804 SP_7 denotes COVID-19
T327 3235-3243 SP_7 denotes COVID-19
T328 3397-3402 NCBITaxon:10239 denotes viral
T329 3436-3441 CHEBI:67079;CHEBI:67079 denotes anti-
T330 3441-3451 NCBITaxon:11632 denotes retroviral
T331 3452-3457 CHEBI:23888;CHEBI:23888 denotes drugs
T332 3493-3500 UBERON:0000948 denotes cardiac
T333 3501-3506 CHEBI:23888;CHEBI:23888 denotes drugs
T334 3591-3602 CHEBI:3638;DG_10;CHEBI:3638 denotes chloroquine
T335 3603-3621 CHEBI:5801;DG_20;CHEBI:5801 denotes hydroxychloroquine
T336 3626-3638 CHEBI:2948;CHEBI:2948 denotes azathioprine
T337 3739-3744 CHEBI:23888;CHEBI:23888 denotes drugs
T338 3835-3841 CHEBI:23888;CHEBI:23888 denotes agents
T339 3897-3908 CHEBI:3638;DG_10;CHEBI:3638 denotes chloroquine
T340 3909-3927 CHEBI:5801;DG_20;CHEBI:5801 denotes hydroxychloroquine
T341 4022-4029 UBERON:0002107 denotes hepatic
T342 4033-4038 UBERON:0002113 denotes renal
T343 4082-4086 CHEBI:23888;CHEBI:23888 denotes drug

2_test

Id Subject Object Predicate Lexical cue
32247212-15897343-25241183 2676-2678 15897343 denotes 17

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
456 391-399 Species denotes patients Tax:9606
457 468-476 Species denotes patients Tax:9606
458 361-369 Disease denotes infected MESH:D007239
459 459-467 Disease denotes COVID-19 MESH:C000657245
466 771-779 Species denotes patients Tax:9606
467 930-938 Species denotes patients Tax:9606
468 1040-1048 Species denotes patients Tax:9606
469 762-770 Disease denotes COVID-19 MESH:C000657245
470 921-929 Disease denotes COVID-19 MESH:C000657245
471 1310-1318 Disease denotes COVID-19 MESH:C000657245
477 1507-1515 Species denotes patients Tax:9606
478 2055-2063 Species denotes patients Tax:9606
479 2202-2210 Species denotes patients Tax:9606
480 1740-1749 Disease denotes infection MESH:D007239
481 2069-2077 Disease denotes COVID-19 MESH:C000657245
485 2348-2356 Species denotes patients Tax:9606
486 2362-2370 Disease denotes COVID-19 MESH:C000657245
487 2409-2430 Disease denotes myocardial infarction MESH:D009203
498 2484-2487 Gene denotes ACE Gene:1636
499 2622-2626 Gene denotes ACE2 Gene:59272
500 2707-2711 Gene denotes ACE2 Gene:59272
501 2687-2697 Species denotes SARS-CoV-2 Tax:2697049
502 2731-2736 Species denotes human Tax:9606
503 2842-2850 Species denotes patients Tax:9606
504 3218-3225 Species denotes patient Tax:9606
505 2565-2573 Disease denotes COVID-19 MESH:C000657245
506 2796-2804 Disease denotes COVID-19 MESH:C000657245
507 3235-3243 Disease denotes COVID-19 MESH:C000657245
518 4000-4003 Gene denotes esp Gene:148713
519 3284-3292 Species denotes patients Tax:9606
520 4008-4016 Species denotes patients Tax:9606
521 3591-3602 Chemical denotes chloroquine MESH:D002738
522 3603-3621 Chemical denotes hydroxychloroquine MESH:D006886
523 3626-3638 Chemical denotes azathioprine MESH:D001379
524 3897-3908 Chemical denotes chloroquine MESH:D002738
525 3909-3927 Chemical denotes hydroxychloroquine MESH:D006886
526 3397-3412 Disease denotes viral infection MESH:D001102
527 4022-4050 Disease denotes hepatic or renal dysfunction MESH:D008107
533 67-75 Species denotes patients Tax:9606
534 185-192 Species denotes patient Tax:9606
535 92-100 Disease denotes COVID-19 MESH:C000657245
536 155-158 Disease denotes CVD MESH:D002318
537 201-209 Disease denotes COVID-19 MESH:C000657245