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PMC:7102599 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id tao:has_standard_notation
2 56-61 Gene denotes Spike Gene:43740568
3 45-55 Species denotes SARS-CoV-2 Tax:2697049
25 306-310 Gene denotes ACE2 Gene:59272
26 433-437 Gene denotes ACE2 Gene:59272
27 559-564 Gene denotes furin Gene:5045
28 187-192 Gene denotes spike Gene:43740568
29 110-120 Species denotes SARS-CoV-2 Tax:2697049
30 175-186 Species denotes Coronavirus Tax:11118
31 288-298 Species denotes SARS-CoV-2 Tax:2697049
32 367-377 Species denotes SARS-CoV-2 Tax:2697049
33 384-392 Species denotes SARS-CoV Tax:694009
34 427-432 Species denotes human Tax:9606
35 480-490 Species denotes SARS-CoV-2 Tax:2697049
36 497-503 Species denotes humans Tax:9606
37 523-533 Species denotes SARS-CoV-2 Tax:2697049
38 691-699 Species denotes SARS-CoV Tax:694009
39 704-721 Species denotes SARS-related CoVs Tax:694009
40 763-773 Species denotes SARS-CoV-2 Tax:2697049
41 904-912 Species denotes SARS-CoV Tax:694009
42 963-973 Species denotes SARS-CoV-2 Tax:2697049
43 915-921 Species denotes murine Tax:10090
44 145-155 Disease denotes infections MESH:D007239
45 167-173 Disease denotes deaths MESH:D003643
48 1165-1169 Gene denotes ACE2 Gene:59272
49 1149-1159 Species denotes SARS-CoV-2 Tax:2697049
52 1195-1205 Species denotes SARS-CoV-2 Tax:2697049
53 1210-1218 Species denotes SARS-CoV Tax:694009
56 1273-1283 Species denotes SARS-CoV-2 Tax:2697049
57 1284-1289 Gene denotes spike Gene:43740568
61 1377-1382 Gene denotes spike Gene:43740568
62 1366-1376 Species denotes SARS-CoV-2 Tax:2697049
63 1327-1335 Species denotes SARS-CoV Tax:694009
71 1502-1506 Gene denotes ACE2 Gene:59272
72 1676-1681 Gene denotes spike Gene:43740568
73 1410-1420 Species denotes SARS-CoV-2 Tax:2697049
74 1496-1501 Species denotes human Tax:9606
75 1590-1600 Species denotes SARS-CoV-2 Tax:2697049
76 1700-1708 Species denotes SARS-CoV Tax:694009
77 1601-1606 Gene denotes spike Gene:43740568
96 1817-1830 Species denotes coronaviruses Tax:11118
97 1893-1899 Species denotes humans Tax:9606
98 1941-1986 Species denotes severe acute respiratory syndrome coronavirus Tax:694009
99 1988-1996 Species denotes SARS-CoV Tax:694009
100 2044-2119 Species denotes Middle-East respiratory syndrome coronavirus (Zaki et al., 2012) (MERS-CoV) Tax:1335626
101 2125-2135 Species denotes SARS-CoV-2 Tax:2697049
102 2176-2184 Species denotes SARS-CoV Tax:694009
103 2309-2315 Species denotes people Tax:9606
104 2349-2357 Species denotes MERS-CoV Tax:1335626
105 2559-2570 Species denotes coronavirus Tax:11118
106 2578-2588 Species denotes SARS-CoV-2 Tax:2697049
107 2742-2752 Species denotes SARS-CoV-2 Tax:2697049
108 2857-2863 Species denotes people Tax:9606
109 3011-3021 Species denotes SARS-CoV-2 Tax:2697049
110 1873-1889 Disease denotes deadly pneumonia MESH:D011014
111 2332-2338 Disease denotes deaths MESH:D003643
112 2804-2813 Disease denotes pneumonia MESH:D011014
113 2815-2825 Disease denotes Covid-2019 MESH:C000657245
144 3083-3091 Species denotes MERS-CoV Tax:1335626
145 3174-3180 Species denotes humans Tax:9606
146 3198-3207 Species denotes dromedary Tax:9838
147 3208-3214 Species denotes camels Tax:9838
148 3266-3274 Species denotes SARS-CoV Tax:694009
149 3279-3289 Species denotes SARS-CoV-2 Tax:2697049
150 3520-3524 Species denotes dogs Tax:9615
151 3597-3605 Species denotes SARS-CoV Tax:694009
152 3623-3629 Species denotes humans Tax:9606
153 3692-3702 Species denotes SARS-CoV-2 Tax:2697049
154 3766-3779 Species denotes coronaviruses Tax:11118
155 3783-3789 Species denotes humans Tax:9606
156 3823-3836 Species denotes coronaviruses Tax:11118
157 3861-3887 Species denotes SARS-related coronaviruses Tax:694009
158 3895-3899 Species denotes CoVs Tax:11118
159 4183-4191 Species denotes SARS-CoV Tax:694009
160 4193-4201 Species denotes MERS-CoV Tax:1335626
161 4207-4217 Species denotes SARS-CoV-2 Tax:2697049
162 4240-4253 Species denotes β-coronavirus Tax:694002
163 4284-4297 Species denotes coronaviruses Tax:11118
164 4313-4319 Species denotes humans Tax:9606
165 4321-4330 Species denotes HCoV-OC43 Tax:31631
166 4332-4341 Species denotes HCoV-HKU1 Tax:290028
167 4343-4352 Species denotes HCoV-NL63 Tax:277944
168 4358-4367 Species denotes HCoV-229E Tax:11137
169 4431-4436 Species denotes human Tax:9606
170 4447-4460 Species denotes coronaviruses Tax:11118
171 3572-3580 Disease denotes zoonotic MESH:D015047
172 3922-3930 Disease denotes zoonotic MESH:D015047
173 4164-4172 Disease denotes zoonotic MESH:D015047
179 4462-4473 Species denotes Coronavirus Tax:11118
180 4809-4813 Species denotes CoVs Tax:11118
181 5479-5483 Species denotes CoVs Tax:11118
182 5946-5957 Species denotes coronavirus Tax:11118
183 4529-4534 Gene denotes spike Gene:43740568
199 6789-6811 Gene denotes dipeptidyl-peptidase 4 Gene:1803
200 6932-6963 Gene denotes angiotensin-converting enzyme 2 Gene:59272
201 6965-6969 Gene denotes ACE2 Gene:59272
202 6147-6160 Species denotes coronaviruses Tax:11118
203 6302-6307 Species denotes human Tax:9606
204 6308-6321 Species denotes coronaviruses Tax:11118
205 6577-6585 Species denotes MERS-CoV Tax:1335626
206 6849-6857 Species denotes SARS-CoV Tax:694009
207 6870-6896 Species denotes SARS-related coronaviruses Tax:694009
208 6898-6907 Species denotes SARSr-CoV Tax:694009
209 6322-6326 Species denotes OC43 Tax:31631
210 6331-6335 Species denotes HKU1 Tax:290028
211 6372-6404 Chemical denotes 5-N-acetyl-9-O-acetyl-sialosides
212 6640-6649 Chemical denotes sialoside
213 6975-6977 Chemical denotes SB MESH:D000965
226 7369-7370 Gene denotes N Gene:43740575
227 7127-7138 Species denotes coronavirus Tax:11118
228 7636-7641 Species denotes human Tax:9606
229 7713-7721 Species denotes SARS-CoV Tax:694009
230 7749-7754 Species denotes MERS- Tax:1335626
231 7795-7803 Species denotes SARS-CoV Tax:694009
232 7810-7818 Species denotes MERS-CoV Tax:1335626
233 8174-8185 Species denotes coronavirus Tax:11118
234 7977-7985 Species denotes SARS-CoV Tax:694009
235 7906-7908 Chemical denotes SB MESH:D000965
236 7269-7278 Disease denotes infection MESH:D007239
237 7699-7707 Disease denotes infected MESH:D007239
268 8255-8259 Gene denotes ACE2 Gene:59272
269 8423-8427 Gene denotes ACE2 Gene:59272
270 8429-8434 Gene denotes hACE2 Gene:59272
271 8572-8577 Gene denotes hACE2 Gene:59272
272 8597-8602 Gene denotes hACE2 Gene:59272
273 8753-8758 Gene denotes furin Gene:5045
274 8274-8284 Species denotes SARS-CoV-2 Tax:2697049
275 8378-8389 Species denotes coronavirus Tax:11118
276 8395-8405 Species denotes SARS-CoV-2 Tax:2697049
277 8417-8422 Species denotes human Tax:9606
278 8464-8472 Species denotes SARS-CoV Tax:694009
279 8657-8667 Species denotes SARS-CoV-2 Tax:2697049
280 8671-8677 Species denotes humans Tax:9606
281 8699-8707 Species denotes SARS-CoV Tax:694009
282 8798-8808 Species denotes SARS-CoV-2 Tax:2697049
283 8895-8903 Species denotes SARS-CoV Tax:694009
284 8914-8918 Species denotes CoVs Tax:11118
285 8974-8984 Species denotes SARS-CoV-2 Tax:2697049
286 9131-9148 Species denotes influenza viruses Tax:11308
287 9164-9187 Species denotes Newcastle disease virus Tax:11176
288 9298-9308 Species denotes SARS-CoV-2 Tax:2697049
289 9430-9438 Species denotes SARS-CoV Tax:694009
290 9445-9453 Species denotes MERS-CoV Tax:1335626
291 9479-9487 Species denotes SARS-CoV Tax:694009
292 9558-9568 Species denotes SARS-CoV-2 Tax:2697049
293 9691-9701 Species denotes SARS-CoV-2 Tax:2697049
294 9703-9711 Species denotes SARS-CoV Tax:694009
295 9717-9726 Species denotes SARSr-CoV Tax:694009
296 9490-9495 Species denotes mouse Tax:10090
297 9364-9366 Chemical denotes SB MESH:D000965
299 9738-9742 Gene denotes ACE2 Gene:59272
319 10440-10445 Gene denotes hACE2 Gene:59272
320 10755-10766 Gene denotes cathepsin L Gene:1514
321 10771-10778 Gene denotes TMPRSS2 Gene:7113
322 10246-10249 Gene denotes bat Gene:570
323 9898-9901 Gene denotes bat Gene:570
324 9783-9793 Species denotes SARS-CoV-2 Tax:2697049
325 9858-9866 Species denotes SARS-CoV Tax:694009
326 9902-9911 Species denotes SARSr-CoV Tax:694009
327 9960-9969 Species denotes SARSr-CoV Tax:694009
328 10029-10043 Species denotes horseshoe bats Tax:49442
329 10069-10078 Species denotes SARSr-CoV Tax:694009
330 10204-10214 Species denotes SARS-CoV-2 Tax:2697049
331 10250-10259 Species denotes SARSr-CoV Tax:694009
332 10324-10328 Species denotes CoVs Tax:11118
333 10401-10409 Species denotes SARS-CoV Tax:694009
334 10554-10564 Species denotes SARS-CoV-2 Tax:2697049
335 10785-10793 Species denotes SARS-CoV Tax:694009
336 10089-10095 Species denotes WIV-16 Tax:1739625
337 10260-10266 CellLine denotes RaTG13 CVCL:AR51
340 11988-11992 Gene denotes ACE2 Gene:59272
341 12022-12032 Species denotes SARS-CoV-2 Tax:2697049
346 12069-12079 Species denotes SARS-CoV-2 Tax:2697049
347 12083-12091 Species denotes SARS-CoV Tax:694009
348 12098-12108 Species denotes SARS-CoV-2 Tax:2697049
349 12048-12051 Species denotes MLV Tax:11786
354 12323-12328 Gene denotes hACE2 Gene:59272
355 12245-12255 Species denotes SARS-CoV-2 Tax:2697049
356 12261-12271 Species denotes SARS-CoV-2 Tax:2697049
357 12224-12227 Species denotes MLV Tax:11786
363 12553-12563 Species denotes SARS-CoV-2 Tax:2697049
364 12588-12596 Species denotes SARS-CoV Tax:694009
365 12601-12610 Species denotes SARSr-CoV Tax:694009
366 12692-12709 Species denotes novel coronavirus Tax:2697049
367 12831-12841 Species denotes SARS-CoV-2 Tax:2697049
374 12973-12981 Species denotes SARS-CoV Tax:694009
375 12989-12999 Species denotes SARS-CoV-2 Tax:2697049
376 13011-13021 Species denotes SARS-CoV-2 Tax:2697049
377 12984-12987 Species denotes MLV Tax:11786
378 13002-13005 Species denotes MLV Tax:11786
379 13031-13034 Species denotes MLV Tax:11786
398 11376-11380 Gene denotes ACE2 Gene:103231639
399 11584-11588 Gene denotes ACE2 Gene:59272
400 11714-11719 Gene denotes hACE2 Gene:59272
401 11823-11828 Gene denotes hACE2 Gene:59272
402 11107-11130 Species denotes a murine leukemia virus Tax:11788
403 11212-11222 Species denotes SARS-CoV-2 Tax:2697049
404 11295-11305 Species denotes SARS-CoV-2 Tax:2697049
405 11316-11324 Species denotes SARS-CoV Tax:694009
406 11393-11401 Species denotes SARS-CoV Tax:694009
407 11536-11546 Species denotes SARS-CoV-2 Tax:2697049
408 11563-11583 Species denotes African green monkey Tax:9534
409 11767-11777 Species denotes SARS-CoV-2 Tax:2697049
410 11858-11868 Species denotes SARS-CoV-2 Tax:2697049
411 11132-11135 Species denotes MLV Tax:11786
412 11308-11311 Species denotes MLV Tax:11786
413 11327-11330 Species denotes MLV Tax:11786
414 11549-11552 Species denotes MLV Tax:11786
415 11780-11783 Species denotes MLV Tax:11786
451 13617-13622 Gene denotes furin Gene:5045
452 13945-13950 Gene denotes furin Gene:5045
453 14423-14430 Gene denotes TMPRSS2 Gene:7113
454 14438-14449 Gene denotes cathepsin L Gene:1514
455 14867-14872 Gene denotes hACE2 Gene:59272
456 13846-13851 Gene denotes furin Gene:5045
457 13301-13306 Gene denotes furin Gene:5045
458 13089-13099 Species denotes SARS-CoV-2 Tax:2697049
459 13223-13231 Species denotes SARS-CoV Tax:694009
460 13238-13247 Species denotes SARSr-CoV Tax:694009
461 13356-13366 Species denotes SARS-CoV-2 Tax:2697049
462 13501-13511 Species denotes SARS-CoV-2 Tax:2697049
463 13693-13701 Species denotes SARS-CoV Tax:694009
464 13829-13839 Species denotes SARS-CoV-2 Tax:2697049
465 14007-14017 Species denotes SARS-CoV-2 Tax:2697049
466 14040-14050 Species denotes SARS-CoV-2 Tax:2697049
467 14062-14072 Species denotes SARS-CoV-2 Tax:2697049
468 14157-14167 Species denotes SARS-CoV-2 Tax:2697049
469 14228-14237 Species denotes SARSr-CoV Tax:694009
470 14259-14269 Species denotes SARS-CoV-2 Tax:2697049
471 14385-14393 Species denotes SARS-CoV Tax:694009
472 14400-14409 Species denotes SARSr-CoV Tax:694009
473 14605-14615 Species denotes SARS-CoV-2 Tax:2697049
474 14744-14754 Species denotes SARS-CoV-2 Tax:2697049
475 14777-14787 Species denotes SARS-CoV-2 Tax:2697049
476 15159-15169 Species denotes SARS-CoV-2 Tax:2697049
477 15257-15265 Species denotes SARS-CoV Tax:694009
478 15270-15279 Species denotes SARSr-CoV Tax:694009
479 14625-14628 Species denotes MLV Tax:11786
480 14764-14767 Species denotes MLV Tax:11786
481 14790-14793 Species denotes MLV Tax:11786
482 15333-15338 Gene denotes furin Gene:5045
483 14111-14119 Chemical denotes arginine MESH:D001120
484 13425-13431 CellLine denotes RaTG13 CVCL:AR51
485 13588-13595 CellLine denotes HEK293T CVCL:0063
488 15493-15498 Gene denotes hACE2 Gene:59272
489 15471-15481 Species denotes SARS-CoV-2 Tax:2697049
496 15573-15578 Gene denotes hACE2 Gene:59272
497 15840-15845 Gene denotes hACE2 Gene:59272
498 16149-16154 Gene denotes hACE2 Gene:59272
499 15560-15568 Species denotes SARS-CoV Tax:694009
500 15849-15857 Species denotes SARS-CoV Tax:694009
501 16054-16062 Species denotes SARS-CoV Tax:694009
505 18745-18750 Gene denotes hACE2 Gene:59272
506 18721-18731 Species denotes SARS-CoV-2 Tax:2697049
507 18779-18787 Species denotes SARS-CoV Tax:694009
512 18790-18798 Gene denotes (A and B
513 18848-18853 Gene denotes hACE2 Gene:59272
514 18880-18890 Species denotes SARS-CoV-2 Tax:2697049
515 18901-18909 Species denotes SARS-CoV Tax:694009
523 19499-19504 Gene denotes hACE2 Gene:59272
524 19136-19146 Species denotes SARS-CoV-2 Tax:2697049
525 19154-19162 Species denotes SARS-CoV Tax:694009
526 19202-19210 Species denotes SARS-CoV Tax:694009
527 19356-19366 Species denotes SARS-CoV-2 Tax:2697049
528 19418-19426 Species denotes SARS-CoV Tax:694009
529 19484-19492 Species denotes SARS-CoV Tax:694009
533 19650-19660 Species denotes SARS-CoV-2 Tax:2697049
534 19664-19672 Species denotes SARS-CoV Tax:694009
535 19676-19678 Disease denotes KD MESH:C537017
539 19576-19581 Gene denotes hACE2 Gene:59272
540 19593-19603 Species denotes SARS-CoV-2 Tax:2697049
541 19611-19619 Species denotes SARS-CoV Tax:694009
545 19914-19923 Gene denotes 2A and 2B
546 19961-19971 Species denotes SARS-CoV-2 Tax:2697049
547 19982-19990 Species denotes SARS-CoV Tax:694009
591 16378-16383 Gene denotes hACE2 Gene:59272
592 16518-16523 Gene denotes hACE2 Gene:59272
593 16624-16629 Gene denotes hACE2 Gene:59272
594 16934-16939 Gene denotes hACE2 Gene:59272
595 17289-17294 Gene denotes hACE2 Gene:59272
596 18021-18026 Gene denotes hACE2 Gene:59272
597 18074-18079 Gene denotes hACE2 Gene:59272
598 18325-18330 Gene denotes hACE2 Gene:59272
599 18470-18475 Gene denotes hACE2 Gene:59272
600 18644-18653 Gene denotes 1A and 1B
601 16335-16345 Species denotes SARS-CoV-2 Tax:2697049
602 16387-16397 Species denotes SARS-CoV-2 Tax:2697049
603 16405-16413 Species denotes SARS-CoV Tax:694009
604 16538-16548 Species denotes SARS-CoV-2 Tax:2697049
605 16556-16564 Species denotes SARS-CoV Tax:694009
606 16639-16649 Species denotes SARS-CoV-2 Tax:2697049
607 16657-16665 Species denotes SARS-CoV Tax:694009
608 16854-16862 Species denotes SARS-CoV Tax:694009
609 16911-16919 Species denotes SARS-CoV Tax:694009
610 17018-17026 Species denotes SARS-CoV Tax:694009
611 17048-17056 Species denotes SARS-CoV Tax:694009
612 17075-17083 Species denotes SARS-CoV Tax:694009
613 17274-17282 Species denotes SARS-CoV Tax:694009
614 17423-17433 Species denotes SARS-CoV-2 Tax:2697049
615 17626-17636 Species denotes SARS-CoV-2 Tax:2697049
616 17725-17735 Species denotes SARS-CoV-2 Tax:2697049
617 17753-17763 Species denotes SARS-CoV-2 Tax:2697049
618 17781-17791 Species denotes SARS-CoV-2 Tax:2697049
619 17809-17819 Species denotes SARS-CoV-2 Tax:2697049
620 17837-17847 Species denotes SARS-CoV-2 Tax:2697049
621 17869-17879 Species denotes SARS-CoV-2 Tax:2697049
622 17987-17997 Species denotes SARS-CoV-2 Tax:2697049
623 18005-18013 Species denotes SARS-CoV Tax:694009
624 18105-18115 Species denotes SARS-CoV-2 Tax:2697049
625 18169-18178 Species denotes SARSr-CoV Tax:694009
626 18251-18260 Species denotes SARSr-CoV Tax:694009
627 18340-18350 Species denotes SARS-CoV-2 Tax:2697049
628 18424-18434 Species denotes SARS-CoV-2 Tax:2697049
629 18522-18530 Species denotes SARS-CoV Tax:694009
630 18677-18687 Species denotes SARS-CoV-2 Tax:2697049
631 18704-18710 Species denotes humans Tax:9606
632 17503-17512 Species denotes Influenza Tax:11552
633 18261-18267 CellLine denotes RaTG13 CVCL:AR51
635 20098-20108 Species denotes SARS-CoV-2 Tax:2697049
643 20286-20291 Gene denotes furin Gene:5045
644 20178-20188 Species denotes SARS-CoV-2 Tax:2697049
645 20688-20698 Species denotes SARS-CoV-2 Tax:2697049
646 21006-21016 Species denotes SARS-CoV-2 Tax:2697049
647 21224-21232 Species denotes SARS-CoV Tax:694009
648 21239-21247 Species denotes MERS-CoV Tax:1335626
649 20416-20423 Chemical denotes proline MESH:D011392
651 22556-22566 Species denotes SARS-CoV-2 Tax:2697049
653 22593-22603 Species denotes SARS-CoV-2 Tax:2697049
656 22638-22646 Gene denotes (B and C
657 22733-22743 Species denotes SARS-CoV-2 Tax:2697049
659 22773-22783 Species denotes SARS-CoV-2 Tax:2697049
662 22933-22943 Species denotes SARS-CoV-2 Tax:2697049
663 22958-22965 Chemical denotes glycans MESH:D011134
666 23435-23444 Gene denotes cryoSPARC Gene:6678
667 23171-23181 Species denotes SARS-CoV-2 Tax:2697049
670 23532-23542 Species denotes SARS-CoV-2 Tax:2697049
671 23547-23555 Species denotes SARS-CoV Tax:694009
678 23624-23634 Species denotes SARS-CoV-2 Tax:2697049
679 23645-23653 Species denotes SARS-CoV Tax:694009
680 23704-23714 Species denotes SARS-CoV-2 Tax:2697049
681 23723-23731 Species denotes SARS-CoV Tax:694009
682 23753-23763 Species denotes SARS-CoV-2 Tax:2697049
683 23772-23780 Species denotes SARS-CoV Tax:694009
688 22088-22091 Gene denotes RBM Gene:347598
689 21585-21595 Species denotes SARS-CoV-2 Tax:2697049
690 22265-22275 Species denotes SARS-CoV-2 Tax:2697049
691 22376-22384 Species denotes SARS-CoV Tax:694009
699 24184-24189 Gene denotes hACE2 Gene:59272
700 24300-24305 Gene denotes hACE2 Gene:59272
701 24457-24461 Gene denotes ACE2 Gene:59272
702 23823-23836 Species denotes β-coronavirus Tax:694002
703 23864-23872 Species denotes SARS-CoV Tax:694009
704 24272-24280 Species denotes SARS-CoV Tax:694009
705 24386-24396 Species denotes SARS-CoV-2 Tax:2697049
712 24780-24790 Species denotes SARS-CoV-2 Tax:2697049
713 24795-24803 Species denotes SARS-CoV Tax:694009
714 25117-25125 Species denotes SARS-CoV Tax:694009
715 25230-25240 Species denotes SARS-CoV-2 Tax:2697049
716 25247-25255 Species denotes SARS-CoV Tax:694009
717 25388-25401 Species denotes coronaviruses Tax:11118
720 26671-26672 Gene denotes N Gene:43740575
721 26658-26668 Species denotes SARS-CoV-2 Tax:2697049
724 26717-26727 Species denotes SARS-CoV-2 Tax:2697049
725 26774-26781 Chemical denotes glycans MESH:D011134
754 26957-26967 Species denotes SARS-CoV-2 Tax:2697049
755 26970-26978 Species denotes SARS-CoV Tax:694009
756 27069-27075 Mutation denotes N122AT p.N122AT
757 27076-27082 Mutation denotes N119ST p.N119ST
758 27090-27096 Mutation denotes T146QT c.146T>QT
759 27104-27110 Mutation denotes N158CT p.N158CT
760 27111-27117 Mutation denotes N234IT p.N234IT
761 27118-27124 Mutation denotes N227IT p.N227IT
762 27125-27131 Mutation denotes N282GT p.N282GT
763 27132-27138 Mutation denotes N269GT rs889888710
764 27139-27145 Mutation denotes N331IT p.N331IT
765 27146-27152 Mutation denotes N318IT p.N318IT
766 27153-27159 Mutation denotes N343AT p.N343AT
767 27160-27166 Mutation denotes N330AT p.N330AT
768 27167-27173 Mutation denotes N370SA p.N370SA
769 27174-27180 Mutation denotes N357ST p.N357ST
770 27181-27187 Mutation denotes N603TS p.N603TS
771 27188-27194 Mutation denotes N589AS p.N589AS
772 27195-27201 Mutation denotes N616CT p.N616CT
773 27202-27208 Mutation denotes N602CT p.N602CT
774 27209-27215 Mutation denotes N657NS p.N657NS
775 27216-27222 Mutation denotes D643TS p.D643TS
776 27223-27229 Mutation denotes N709NS p.N709NS
777 27230-27236 Mutation denotes N691NT p.N691NT
778 27237-27243 Mutation denotes N717FT p.N717FT
779 27244-27250 Mutation denotes N699FS p.N699FS
780 27251-27257 Mutation denotes N801FS p.N801FS
781 27258-27264 Mutation denotes N783FS p.N783FS
785 26895-26896 Gene denotes N Gene:43740575
786 26929-26939 Species denotes SARS-CoV-2 Tax:2697049
787 26946-26954 Species denotes SARS-CoV Tax:694009
790 27487-27497 Species denotes SARS-CoV-2 Tax:2697049
791 27463-27470 Chemical denotes Glycans MESH:D011134
807 26196-26197 Gene denotes N Gene:43740575
808 25847-25848 Gene denotes N Gene:43740575
809 25429-25440 Species denotes coronavirus Tax:11118
810 25822-25832 Species denotes SARS-CoV-2 Tax:2697049
811 25994-26002 Species denotes SARS-CoV Tax:694009
812 26183-26193 Species denotes SARS-CoV-2 Tax:2697049
813 26244-26252 Species denotes SARS-CoV Tax:694009
814 26375-26385 Species denotes SARS-CoV-2 Tax:2697049
815 26392-26400 Species denotes SARS-CoV Tax:694009
816 26479-26488 Species denotes SARSr-CoV Tax:694009
817 25496-25512 Chemical denotes N-linked glycans
818 25617-25633 Chemical denotes oligosaccharides MESH:D009844
819 25895-25911 Chemical denotes oligosaccharides MESH:D009844
820 26293-26300 Chemical denotes glycans MESH:D011134
821 26329-26336 Chemical denotes glycans MESH:D011134
824 27547-27555 Species denotes SARS-CoV Tax:694009
825 27591-27601 Species denotes SARS-CoV-2 Tax:2697049
828 28216-28224 Species denotes SARS-CoV Tax:694009
829 28259-28269 Species denotes SARS-CoV-2 Tax:2697049
833 28303-28311 Gene denotes (A and B
834 28382-28392 Species denotes SARS-CoV-2 Tax:2697049
835 28489-28499 Species denotes SARS-CoV-2 Tax:2697049
842 28594-28604 Species denotes SARS-CoV-2 Tax:2697049
843 28615-28623 Species denotes SARS-CoV Tax:694009
844 28660-28668 Species denotes SARS-CoV Tax:694009
845 28607-28610 Species denotes MLV Tax:11786
846 28626-28629 Species denotes MLV Tax:11786
847 28671-28676 Species denotes mouse Tax:10090
852 27945-27949 Gene denotes ACE2 Gene:59272
853 27839-27848 Gene denotes 5A and 5B
854 27820-27822 Chemical denotes SA
855 27827-27829 Chemical denotes SB MESH:D000965
868 28932-28936 Species denotes mice Tax:10090
869 28965-28973 Species denotes SARS-CoV Tax:694009
870 28987-28997 Species denotes SARS-CoV-2 Tax:2697049
871 29005-29013 Species denotes SARS-CoV Tax:694009
872 29103-29111 Species denotes SARS-CoV Tax:694009
873 29130-29140 Species denotes SARS-CoV-2 Tax:2697049
874 29259-29269 Species denotes SARS-CoV-2 Tax:2697049
875 29360-29370 Species denotes SARS-CoV-2 Tax:2697049
876 29377-29385 Species denotes SARS-CoV Tax:694009
877 29114-29117 Species denotes MLV Tax:11786
878 29143-29146 Species denotes MLV Tax:11786
879 29416-29423 Chemical denotes glycans MESH:D011134
897 29743-29748 Gene denotes hACE2 Gene:59272
898 30138-30143 Gene denotes hACE2 Gene:59272
899 30232-30236 Gene denotes ACE2 Gene:59272
900 30454-30459 Gene denotes hACE2 Gene:59272
901 29728-29736 Species denotes SARS-CoV Tax:694009
902 29837-29843 Species denotes humans Tax:9606
903 29872-29880 Species denotes SARS-CoV Tax:694009
904 29978-29984 Species denotes humans Tax:9606
905 30382-30388 Species denotes humans Tax:9606
906 30438-30448 Species denotes SARS-CoV-2 Tax:2697049
907 30540-30548 Species denotes SARS-CoV Tax:694009
908 30603-30609 Species denotes humans Tax:9606
909 30642-30652 Species denotes SARS-CoV-2 Tax:2697049
910 30653-30658 Species denotes human Tax:9606
911 30662-30667 Species denotes human Tax:9606
912 29620-29635 Disease denotes viral infection MESH:D001102
913 30309-30327 Disease denotes SARS-CoV infection MESH:C000657245
936 31185-31189 Gene denotes DPP4 Gene:1803
937 31106-31109 Gene denotes bat Gene:570
938 31821-31826 Gene denotes furin Gene:5045
939 31720-31725 Gene denotes furin Gene:5045
940 30962-30970 Species denotes MERS-CoV Tax:1335626
941 30979-30999 Species denotes bat coronavirus HKU4 Tax:694007
942 31005-31010 Species denotes human Tax:9606
943 31133-31138 Species denotes human Tax:9606
944 31179-31184 Species denotes human Tax:9606
945 31410-31415 Species denotes human Tax:9606
946 31584-31601 Species denotes influenza viruses Tax:11308
947 31617-31640 Species denotes Newcastle disease virus Tax:11176
948 31697-31707 Species denotes SARS-CoV-2 Tax:2697049
949 31846-31856 Species denotes SARS-CoV-2 Tax:2697049
950 31870-31878 Species denotes SARS-CoV Tax:694009
951 31886-31895 Species denotes SARSr-CoV Tax:694009
952 32231-32241 Species denotes SARS-CoV-2 Tax:2697049
953 32279-32287 Species denotes SARS-CoV Tax:694009
954 31352-31356 Species denotes HKU4 Tax:694007
955 32179-32184 Gene denotes furin Gene:5045
956 31512-31517 Gene denotes furin Gene:5045
957 31264-31270 Chemical denotes glycan MESH:D011134
984 34259-34264 Gene denotes hACE2 Gene:59272
985 32396-32409 Species denotes coronaviruses Tax:11118
986 32596-32604 Species denotes SARS-CoV Tax:694009
987 32611-32619 Species denotes MERS-CoV Tax:1335626
988 32768-32778 Species denotes SARS-CoV-2 Tax:2697049
989 33165-33170 Species denotes human Tax:9606
990 33181-33194 Species denotes coronaviruses Tax:11118
991 33196-33205 Species denotes HCoV-NL63 Tax:277944
995 33340-33349 Species denotes HCoV-NL63 Tax:277944
996 33354-33363 Species denotes HCoV-229E Tax:11137
997 33798-33811 Species denotes coronaviruses Tax:11118
998 34027-34032 Species denotes human Tax:9606
999 34033-34046 Species denotes coronaviruses Tax:11118
1000 34127-34132 Species denotes human Tax:9606
1001 34133-34146 Species denotes coronaviruses Tax:11118
1002 34246-34254 Species denotes SARS-CoV Tax:694009
1003 34474-34487 Species denotes coronaviruses Tax:11118
1004 34597-34607 Species denotes SARS-CoV-2 Tax:2697049
1005 34609-34617 Species denotes SARS-CoV Tax:694009
1006 34622-34630 Species denotes MERS-CoV Tax:1335626
1007 32441-32447 Chemical denotes glycan MESH:D011134
1008 32854-32856 Chemical denotes SB MESH:D000965
1009 32505-32513 Disease denotes infected MESH:D007239
1026 34819-34824 Gene denotes hACE2 Gene:59272
1027 35522-35525 Gene denotes RBM Gene:347598
1028 34703-34713 Species denotes SARS-CoV-2 Tax:2697049
1029 34720-34728 Species denotes SARS-CoV Tax:694009
1030 34909-34917 Species denotes SARS-CoV Tax:694009
1031 34976-34986 Species denotes SARS-CoV-2 Tax:2697049
1032 35164-35174 Species denotes SARS-CoV-2 Tax:2697049
1033 35179-35187 Species denotes SARS-CoV Tax:694009
1034 35419-35427 Species denotes SARS-CoV Tax:694009
1035 35670-35680 Species denotes SARS-CoV-2 Tax:2697049
1036 35685-35693 Species denotes SARS-CoV Tax:694009
1037 35841-35852 Species denotes coronavirus Tax:11118
1038 35937-35947 Species denotes SARS-CoV-2 Tax:2697049
1039 35965-35969 Species denotes CoVs Tax:11118
1040 35229-35231 Chemical denotes SB MESH:D000965
1041 35330-35347 Disease denotes SARS-CoV-infected MESH:C000657245
1067 37242-37245 Gene denotes CRL Gene:133396
1068 37407-37412 Gene denotes furin Gene:5045
1069 37452-37456 Gene denotes ACE2 Gene:59272
1070 38417-38426 Gene denotes CryoSPARC Gene:6678
1071 37611-37612 Gene denotes N Gene:43740575
1072 37512-37513 Gene denotes N Gene:43740575
1073 37474-37475 Gene denotes N Gene:43740575
1074 37441-37442 Gene denotes N Gene:43740575
1075 38456-38465 Gene denotes cryosparc Gene:6678
1076 36748-36756 Gene denotes Thrombin Gene:14061
1077 36666-36670 Species denotes Mice Tax:10090
1078 36998-37008 Species denotes SARS-CoV-2 Tax:2697049
1079 37057-37067 Species denotes SARS-CoV-2 Tax:2697049
1080 37319-37326 Species denotes Hamster Tax:10034
1081 37391-37401 Species denotes SARS-CoV-2 Tax:2697049
1082 37488-37498 Species denotes SARS-CoV-2 Tax:2697049
1083 37526-37534 Species denotes SARS-CoV Tax:694009
1084 37588-37598 Species denotes SARS-CoV-2 Tax:2697049
1085 37650-37658 Species denotes SARS-CoV Tax:694009
1086 37697-37718 Species denotes murine leukemia virus Tax:11786
1087 36587-36592 Species denotes Human Tax:9606
1088 38836-38844 Chemical denotes Superose
1089 38923-38929 Chemical denotes Carbon MESH:D002244
1090 37158-37164 CellLine denotes HEK293 CVCL:0045
1091 37190-37197 CellLine denotes HEK293T CVCL:0063
1105 39487-39492 Species denotes human Tax:9606
1106 39732-39737 Species denotes human Tax:9606
1107 39820-39840 Species denotes African green monkey Tax:9534
1108 39692-39695 Chemical denotes CO2 MESH:D002245
1109 39937-39940 Chemical denotes CO2 MESH:D002245
1110 39956-39960 Chemical denotes DMEM
1111 39976-39986 Chemical denotes penicillin MESH:D010406
1112 39987-39999 Chemical denotes streptomycin MESH:D013307
1113 39493-39509 Disease denotes embryonic kidney MESH:D007674
1114 39738-39754 Disease denotes embryonic kidney MESH:D007674
1115 39467-39473 CellLine denotes HEK293 CVCL:0045
1116 39587-39594 CellLine denotes HEK293F CVCL:6642
1117 39709-39716 CellLine denotes HEK293T CVCL:0063
1120 40118-40128 Species denotes SARS-CoV-2 Tax:2697049
1121 40133-40141 Species denotes SARS-CoV Tax:694009
1135 40702-40703 Gene denotes N Gene:43740575
1136 40577-40578 Gene denotes N Gene:43740575
1137 40149-40157 Species denotes SARS-CoV Tax:694009
1138 40189-40197 Species denotes SARS-CoV Tax:694009
1139 40501-40511 Species denotes SARS-CoV-2 Tax:2697049
1140 40382-40391 Chemical denotes histidine MESH:D006639
1141 40640-40649 Chemical denotes histidine MESH:D006639
1142 40909-40912 Chemical denotes CO2 MESH:D002245
1143 41269-41275 Chemical denotes Cobalt MESH:D003035
1144 41361-41365 Chemical denotes Tris
1145 41384-41388 Chemical denotes NaCl MESH:D012965
1146 41408-41411 Chemical denotes SDS MESH:D012967
1147 40790-40797 CellLine denotes HEK293F CVCL:6642
1167 41552-41556 Gene denotes ACE2 Gene:59272
1168 41728-41736 Gene denotes thrombin Gene:2147
1169 41747-41752 Gene denotes hACE2 Gene:59272
1170 42556-42564 Gene denotes thrombin Gene:2147
1171 42627-42631 Gene denotes ACE2 Gene:59272
1172 42659-42667 Gene denotes thrombin Gene:2147
1173 41504-41509 Species denotes human Tax:9606
1174 41600-41605 Species denotes human Tax:9606
1175 41510-41539 Gene denotes angiotensin-converting enzyme Gene:1636
1176 41894-41897 Chemical denotes CO2 MESH:D002245
1177 42499-42507 Chemical denotes Tris-HCl
1178 42524-42528 Chemical denotes NaCl MESH:D012965
1179 42674-42680 Chemical denotes mMTris
1180 42681-42684 Chemical denotes HCl MESH:D006851
1181 42699-42703 Chemical denotes NaCl MESH:D012965
1182 42715-42720 Chemical denotes CaCl2 MESH:D002122
1183 43012-43016 Chemical denotes Tris
1184 43035-43039 Chemical denotes NaCl MESH:D012965
1185 41775-41782 CellLine denotes HEK293F CVCL:6642
1196 43181-43189 Species denotes SARS-CoV Tax:694009
1197 43193-43203 Species denotes SARS-CoV-2 Tax:2697049
1198 43211-43221 Species denotes SARS-CoV-2 Tax:2697049
1199 43171-43174 Species denotes MLV Tax:11786
1200 43421-43424 Species denotes MLV Tax:11786
1201 43461-43464 Species denotes MLV Tax:11786
1202 43351-43369 Chemical denotes Lipofectamine 2000 MESH:C086724
1203 43650-43654 Chemical denotes DMEM
1204 43674-43678 Chemical denotes DMEM
1205 43311-43318 CellLine denotes HEK293T CVCL:0063
1217 43898-43906 Species denotes SARS-CoV Tax:694009
1218 43910-43920 Species denotes SARS-CoV-2 Tax:2697049
1219 43928-43938 Species denotes SARS-CoV-2 Tax:2697049
1220 44158-44166 Species denotes SARS-CoV Tax:694009
1221 44258-44263 Species denotes human Tax:9606
1222 44267-44272 Species denotes mouse Tax:10090
1223 43981-43984 Chemical denotes SDS MESH:D012967
1224 44085-44089 Chemical denotes Tris
1225 44090-44097 Chemical denotes Glycine MESH:D005998
1226 44132-44136 Chemical denotes PVDF MESH:C024865
1227 44221-44236 Chemical denotes Alexa Fluor 680
1234 44681-44685 Gene denotes ACE2 Gene:101823817
1235 44522-44526 Chemical denotes DMEM
1236 44877-44881 Chemical denotes DMEM
1237 44931-44935 Chemical denotes DMEM
1238 44988-44997 Disease denotes infection MESH:D007239
1239 45316-45325 Disease denotes infection MESH:D007239
1248 45897-45901 Gene denotes ACE2 Gene:59272
1249 46368-46372 Gene denotes ACE2 Gene:59272
1250 45723-45733 Species denotes SARS-CoV-2 Tax:2697049
1251 45740-45748 Species denotes SARS-CoV Tax:694009
1252 46336-46344 Species denotes SARS-CoV Tax:694009
1253 46349-46359 Species denotes SARS-CoV-2 Tax:2697049
1254 45525-45534 Chemical denotes Octet Red
1255 45635-45640 Chemical denotes water MESH:D014867
1262 46461-46471 Species denotes SARS-CoV-2 Tax:2697049
1263 46655-46658 Chemical denotes CO2 MESH:D002245
1264 46994-47000 Chemical denotes Cobalt MESH:D003035
1265 47119-47123 Chemical denotes Tris
1266 47142-47146 Chemical denotes NaCl MESH:D012965
1267 46536-46543 CellLine denotes HEK293F CVCL:6642
1269 47239-47249 Species denotes SARS-CoV-2 Tax:2697049
1276 49455-49464 Gene denotes CryoSPARC Gene:6678
1277 49268-49277 Gene denotes cryoSPARC Gene:6678
1278 49120-49129 Gene denotes cryoSPARC Gene:6678
1279 49046-49055 Gene denotes cryoSPARC Gene:6678
1280 48581-48590 Gene denotes cryoSPARC Gene:6678
1281 48911-48921 Species denotes SARS-CoV-2 Tax:2697049
1286 50053-50054 Gene denotes N Gene:43740575
1287 50192-50198 Chemical denotes Glycan MESH:D011134
1288 50321-50331 Chemical denotes saccharide MESH:D002241
1289 50649-50655 Chemical denotes glycan MESH:D011134
1291 50803-50811 Species denotes SARS-CoV Tax:694009
1298 50822-50826 Species denotes mice Tax:10090
1299 50998-51002 Species denotes mice Tax:10090
1300 51030-51040 Species denotes SARS-CoV 2 Tax:2697049
1301 51147-51150 Chemical denotes PBS MESH:D007854
1302 50944-50950 Disease denotes Cancer MESH:D009369
1303 51460-51466 Disease denotes Cancer MESH:D009369
1306 52034-52044 Species denotes SARS-CoV-2 Tax:2697049
1307 52086-52096 Species denotes SARS-CoV-2 Tax:2697049

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 62-74 Body_part denotes Glycoprotein http://purl.org/sig/ont/fma/fma62925
T2 197-210 Body_part denotes glycoproteins http://purl.org/sig/ont/fma/fma62925
T3 230-235 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T4 320-325 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T5 536-548 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T6 996-1001 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T7 1186-1191 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T8 1290-1302 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T9 1403-1408 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T10 1557-1562 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T11 1607-1619 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T12 3497-3501 Body_part denotes palm http://purl.org/sig/ont/fma/fma24920
T13 4490-4495 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T14 4539-4551 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T15 4712-4716 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T16 4767-4785 Body_part denotes cellular membranes http://purl.org/sig/ont/fma/fma63841
T17 5698-5705 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T18 5981-5986 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T19 6099-6106 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T20 6124-6128 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T21 6414-6427 Body_part denotes glycoproteins http://purl.org/sig/ont/fma/fma62925
T22 6432-6443 Body_part denotes glycolipids http://purl.org/sig/ont/fma/fma82780
T23 6456-6468 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T24 6456-6460 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T25 6502-6507 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T26 6994-6999 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T27 7141-7153 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T28 7202-7207 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T29 7678-7683 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T30 8307-8312 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T31 9021-9026 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T32 9549-9554 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T33 9796-9808 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T34 9820-9830 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T35 9931-9943 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T36 10347-10360 Body_part denotes glycoproteins http://purl.org/sig/ont/fma/fma62925
T37 10371-10381 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T38 10472-10483 Body_part denotes pneumocytes http://purl.org/sig/ont/fma/fma62499
T39 10520-10530 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T40 11095-11100 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T41 11254-11259 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T42 11343-11348 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T43 11487-11492 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T44 11662-11667 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T45 12128-12133 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T46 12288-12293 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T47 12613-12626 Body_part denotes glycoproteins http://purl.org/sig/ont/fma/fma62925
T48 12799-12809 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T49 13133-13143 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T50 13596-13601 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T51 13636-13647 Body_part denotes compartment http://purl.org/sig/ont/fma/fma76577
T52 13908-13918 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T53 14111-14119 Body_part denotes arginine http://purl.org/sig/ont/fma/fma82763
T54 14368-14372 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T55 14723-14728 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T56 14888-14893 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T57 15143-15155 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T58 17434-17440 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T59 18621-18634 Body_part denotes glycoproteins http://purl.org/sig/ont/fma/fma62925
T60 18963-18970 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T61 19312-19322 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T62 20030-20037 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T63 20111-20123 Body_part denotes Glycoprotein http://purl.org/sig/ont/fma/fma62925
T64 20191-20203 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T65 20416-20423 Body_part denotes proline http://purl.org/sig/ont/fma/fma82761
T66 21854-21857 Body_part denotes map http://purl.org/sig/ont/fma/fma67847
T67 22191-22194 Body_part denotes map http://purl.org/sig/ont/fma/fma67847
T68 22569-22581 Body_part denotes Glycoprotein http://purl.org/sig/ont/fma/fma62925
T69 22633-22636 Body_part denotes map http://purl.org/sig/ont/fma/fma67847
T70 22813-22816 Body_part denotes map http://purl.org/sig/ont/fma/fma67847
T71 23414-23417 Body_part denotes map http://purl.org/sig/ont/fma/fma67847
T72 23839-23852 Body_part denotes glycoproteins http://purl.org/sig/ont/fma/fma62925
T73 24474-24486 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T74 24474-24478 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T75 25070-25073 Body_part denotes map http://purl.org/sig/ont/fma/fma67847
T76 25443-25456 Body_part denotes glycoproteins http://purl.org/sig/ont/fma/fma62925
T77 25617-25633 Body_part denotes oligosaccharides http://purl.org/sig/ont/fma/fma82742
T78 25756-25764 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T79 25895-25911 Body_part denotes oligosaccharides http://purl.org/sig/ont/fma/fma82742
T80 25940-25943 Body_part denotes map http://purl.org/sig/ont/fma/fma67847
T81 26491-26504 Body_part denotes glycoproteins http://purl.org/sig/ont/fma/fma62925
T82 26806-26809 Body_part denotes map http://purl.org/sig/ont/fma/fma67847
T83 27508-27511 Body_part denotes map http://purl.org/sig/ont/fma/fma67847
T84 28192-28205 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T85 28235-28245 Body_part denotes Antibodies http://purl.org/sig/ont/fma/fma62871
T86 28297-28302 Body_part denotes Cells http://purl.org/sig/ont/fma/fma68646
T87 28353-28366 Body_part denotes glycoproteins http://purl.org/sig/ont/fma/fma62925
T88 28695-28701 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T89 28915-28921 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T90 29043-29048 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T91 29189-29194 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T92 29297-29302 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T93 29669-29673 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T94 29678-29684 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T95 30730-30734 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T96 30763-30775 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T97 31011-31016 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T98 31139-31144 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T99 31416-31421 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T100 31977-31982 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T101 32242-32246 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T102 32251-32257 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T103 33384-33391 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T104 33979-33991 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T105 34503-34515 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T106 34731-34744 Body_part denotes glycoproteins http://purl.org/sig/ont/fma/fma62925
T107 34841-34846 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T108 35009-35014 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T109 35715-35725 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T110 36169-36182 Body_part denotes glycoproteins http://purl.org/sig/ont/fma/fma62925
T111 36530-36540 Body_part denotes Antibodies http://purl.org/sig/ont/fma/fma62871
T112 36593-36596 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T113 36739-36747 Body_part denotes Proteins http://purl.org/sig/ont/fma/fma67257
T114 37137-37141 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T115 37327-37333 Body_part denotes Kidney http://purl.org/sig/ont/fma/fma7203
T116 37382-37385 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T117 37719-37722 Body_part denotes gag http://purl.org/sig/ont/fma/fma63011
T118 38790-38797 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T119 39456-39460 Body_part denotes Cell http://purl.org/sig/ont/fma/fma68646
T120 39503-39509 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T121 39510-39514 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T122 39595-39600 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T123 39748-39754 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T124 39755-39759 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T125 39792-39798 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T126 39799-39814 Body_part denotes epithelial cell http://purl.org/sig/ont/fma/fma66768
T127 39810-39814 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T128 39851-39857 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T129 39858-39862 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T130 39901-39906 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T131 40001-40006 Body_part denotes Cells http://purl.org/sig/ont/fma/fma68646
T132 40382-40391 Body_part denotes histidine http://purl.org/sig/ont/fma/fma82755
T133 40640-40649 Body_part denotes histidine http://purl.org/sig/ont/fma/fma82755
T134 40798-40803 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T135 41027-41032 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T136 41065-41070 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T137 41143-41148 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T138 41206-41214 Body_part denotes Proteins http://purl.org/sig/ont/fma/fma67257
T139 41606-41609 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T140 41783-41788 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T141 42012-42017 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T142 42050-42055 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T143 42126-42131 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T144 42279-42288 Body_part denotes Sartorius http://purl.org/sig/ont/fma/fma22353
T145 42343-42350 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T146 42793-42800 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T147 42830-42837 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T148 42866-42873 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T149 43054-43061 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T150 43319-43324 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T151 43425-43428 Body_part denotes Gag http://purl.org/sig/ont/fma/fma63011
T152 43559-43564 Body_part denotes Cells http://purl.org/sig/ont/fma/fma68646
T153 43622-43627 Body_part denotes Cells http://purl.org/sig/ont/fma/fma68646
T154 44090-44097 Body_part denotes Glycine http://purl.org/sig/ont/fma/fma82753
T155 44188-44196 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T156 44283-44291 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T157 44478-44483 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T158 44542-44547 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T159 44620-44625 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T160 44953-44958 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T161 45037-45042 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T162 45219-45225 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T163 45378-45383 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T164 46421-46428 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T165 46544-46549 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T166 46764-46769 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T167 46802-46807 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T168 46880-46885 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T169 47036-47043 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T170 49856-49859 Body_part denotes map http://purl.org/sig/ont/fma/fma67847
T171 49939-49942 Body_part denotes map http://purl.org/sig/ont/fma/fma67847
T172 50048-50051 Body_part denotes map http://purl.org/sig/ont/fma/fma67847
T173 50075-50079 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T174 50637-50644 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T175 51305-51311 Body_part denotes Plasma http://purl.org/sig/ont/fma/fma62970
T176 51962-51969 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T177 52324-52334 Body_part denotes Amino Acid http://purl.org/sig/ont/fma/fma82739
T178 52372-52385 Body_part denotes Glycoproteins http://purl.org/sig/ont/fma/fma62925
T179 53692-53700 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 23210-23215 Body_part denotes Scale http://purl.obolibrary.org/obo/UBERON_0002542
T2 23253-23258 Body_part denotes shell http://purl.obolibrary.org/obo/UBERON_0006612
T3 28192-28205 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T4 29678-29684 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T5 32251-32257 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T6 33831-33836 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T7 37327-37333 Body_part denotes Kidney http://purl.obolibrary.org/obo/UBERON_0002113
T8 39503-39509 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T9 39748-39754 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T10 39792-39798 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T11 39851-39857 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T12 49526-49531 Body_part denotes shell http://purl.obolibrary.org/obo/UBERON_0006612
T13 49581-49586 Body_part denotes shell http://purl.obolibrary.org/obo/UBERON_0006612
T14 50075-50079 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T15 51219-51223 Body_part denotes tail http://purl.obolibrary.org/obo/UBERON_0002415

LitCovid_AGAC

Id Subject Object Predicate Lexical cue
p52222s6 5685-5693 PosReg denotes activate
p52222s8 5698-5705 Protein denotes protein
p52243s16 8050-8059 PosReg denotes promoting
p52243s17 8060-8101 MPA denotes S fusogenic conformational rearrangements
p52305s30 15221-15237 MPA denotes its transmissibi
p52311s7 15829-15836 Interaction denotes binding
p52328s35 18314-18321 Interaction denotes binding

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 45-53 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T2 110-118 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T3 145-155 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T4 288-296 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T5 367-375 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T6 384-392 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T7 480-488 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T8 523-531 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T9 691-699 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T10 704-708 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T11 763-771 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T12 904-912 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T13 963-971 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T14 1149-1157 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T15 1195-1203 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T16 1210-1218 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T17 1273-1281 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T18 1327-1335 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T19 1366-1374 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T20 1410-1418 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T21 1590-1598 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T22 1700-1708 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T23 1880-1889 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T24 1941-1974 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T25 1988-1996 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T26 2125-2133 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T27 2176-2184 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T28 2578-2586 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T29 2742-2750 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T30 2804-2813 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T31 2815-2825 Disease denotes Covid-2019 http://purl.obolibrary.org/obo/MONDO_0100096
T32 3011-3019 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T33 3266-3274 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T34 3279-3287 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T35 3597-3605 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T36 3692-3700 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T37 3861-3865 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T38 4183-4191 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T39 4207-4215 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T40 6849-6857 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T41 6870-6874 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T42 7269-7278 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T43 7713-7721 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T44 7795-7803 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T45 7977-7985 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T46 8274-8282 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T47 8395-8403 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T48 8464-8472 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T49 8657-8665 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T50 8699-8707 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T51 8798-8806 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T52 8895-8903 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T53 8974-8982 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T54 9125-9140 Disease denotes avian influenza http://purl.obolibrary.org/obo/MONDO_0018695
T55 9131-9140 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T56 9164-9181 Disease denotes Newcastle disease http://purl.obolibrary.org/obo/MONDO_0005875
T57 9298-9306 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T58 9430-9438 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T59 9479-9487 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T60 9558-9566 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T61 9691-9699 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T62 9703-9711 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T63 9768-9776 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T64 9783-9791 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T65 9858-9866 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T66 10204-10212 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T67 10401-10409 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T68 10554-10562 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T69 10785-10793 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T70 11116-11124 Disease denotes leukemia http://purl.obolibrary.org/obo/MONDO_0005059
T71 11212-11220 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T72 11295-11303 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T73 11316-11324 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T74 11393-11401 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T75 11536-11544 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T76 11767-11775 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T77 11858-11866 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T78 12022-12030 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T79 12069-12077 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T80 12083-12091 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T81 12098-12106 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T82 12245-12253 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T83 12261-12269 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T84 12553-12561 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T85 12588-12596 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T86 12831-12839 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T87 12973-12981 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T88 12989-12997 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T89 13011-13019 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T90 13089-13097 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T91 13223-13231 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T92 13356-13364 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T93 13501-13509 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T94 13693-13701 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T95 13829-13837 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T96 14007-14015 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T97 14040-14048 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T98 14062-14070 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T99 14157-14165 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T100 14259-14267 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T101 14385-14393 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T102 14605-14613 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T103 14744-14752 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T104 14777-14785 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T105 15159-15167 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T106 15257-15265 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T107 15471-15479 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T108 15527-15535 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T109 15560-15568 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T110 15849-15857 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T111 16054-16062 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T112 16335-16343 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T113 16387-16395 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T114 16405-16413 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T115 16538-16546 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T116 16556-16564 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T117 16639-16647 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T118 16657-16665 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T119 16854-16862 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T120 16911-16919 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T121 17018-17026 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T122 17048-17056 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T123 17075-17083 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T124 17274-17282 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T125 17423-17431 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T126 17503-17512 Disease denotes Influenza http://purl.obolibrary.org/obo/MONDO_0005812
T127 17626-17634 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T128 17987-17995 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T129 18005-18013 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T130 18105-18113 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T131 18116-18127 Disease denotes S sequences http://purl.obolibrary.org/obo/MONDO_0007821
T132 18233-18244 Disease denotes S sequences http://purl.obolibrary.org/obo/MONDO_0007821
T133 18340-18348 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T134 18424-18432 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T135 18522-18530 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T136 18677-18685 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T137 18721-18729 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T138 18779-18787 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T139 18880-18888 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T140 18901-18909 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T141 19136-19144 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T142 19154-19162 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T143 19202-19210 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T144 19356-19364 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T145 19418-19426 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T146 19484-19492 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T147 19593-19601 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T148 19611-19619 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T149 19650-19658 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T150 19664-19672 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T151 19961-19969 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T152 19982-19990 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T153 20098-20106 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T154 20178-20186 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T155 20688-20696 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T156 21006-21014 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T157 21224-21232 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T158 21585-21593 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T159 22265-22273 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T160 22376-22384 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T161 22556-22564 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T162 22593-22601 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T163 22733-22741 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T164 22773-22781 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T165 22933-22941 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T166 23171-23179 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T167 23532-23540 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T168 23547-23555 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T169 23624-23632 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T170 23645-23653 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T171 23704-23712 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T172 23723-23731 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T173 23753-23761 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T174 23772-23780 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T175 23864-23872 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T176 24272-24280 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T177 24386-24394 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T178 24780-24788 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T179 24795-24803 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T180 25117-25125 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T181 25230-25238 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T182 25247-25255 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T183 25822-25830 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T184 25994-26002 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T185 26183-26191 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T186 26244-26252 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T187 26375-26383 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T188 26392-26400 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T189 26658-26666 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T190 26717-26725 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T191 26929-26937 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T192 26946-26954 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T193 26957-26965 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T194 26970-26978 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T195 27487-27495 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T196 27547-27555 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T197 27591-27599 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T198 27657-27668 Disease denotes S sequences http://purl.obolibrary.org/obo/MONDO_0007821
T199 28216-28224 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T200 28259-28267 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T201 28382-28390 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T202 28489-28497 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T203 28500-28511 Disease denotes S sequences http://purl.obolibrary.org/obo/MONDO_0007821
T204 28594-28602 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T205 28615-28623 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T206 28660-28668 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T207 28965-28973 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T208 28987-28995 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T209 29005-29013 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T210 29103-29111 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T211 29130-29138 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T212 29259-29267 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T213 29360-29368 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T214 29377-29385 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T215 29620-29635 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T216 29626-29635 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T217 29728-29736 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T218 29872-29880 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T219 30309-30327 Disease denotes SARS-CoV infection http://purl.obolibrary.org/obo/MONDO_0005091
T220 30318-30327 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T221 30438-30446 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T222 30540-30548 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T223 30642-30650 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T224 31578-31593 Disease denotes avian influenza http://purl.obolibrary.org/obo/MONDO_0018695
T225 31584-31593 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T226 31617-31634 Disease denotes Newcastle disease http://purl.obolibrary.org/obo/MONDO_0005875
T227 31697-31705 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T228 31846-31854 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T229 31870-31878 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T230 32231-32239 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T231 32279-32287 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T232 32596-32604 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T233 32768-32776 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T234 34163-34175 Disease denotes common colds http://purl.obolibrary.org/obo/MONDO_0005709
T235 34246-34254 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T236 34597-34605 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T237 34609-34617 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T238 34703-34711 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T239 34720-34728 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T240 34909-34917 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T241 34976-34984 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T242 35164-35172 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T243 35179-35187 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T244 35330-35338 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T245 35419-35427 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T246 35670-35678 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T247 35685-35693 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T248 35937-35945 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T249 36458-36462 Disease denotes STAR http://purl.obolibrary.org/obo/MONDO_0010408
T250 36998-37006 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T251 37057-37065 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T252 37391-37399 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T253 37488-37496 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T254 37526-37534 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T255 37588-37596 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T256 37650-37658 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T257 37704-37712 Disease denotes leukemia http://purl.obolibrary.org/obo/MONDO_0005059
T258 38798-38802 Disease denotes A HP http://purl.obolibrary.org/obo/MONDO_0013564
T259 40118-40126 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T260 40133-40141 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T261 40149-40157 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T262 40189-40197 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T263 40501-40509 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T264 43181-43189 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T265 43193-43201 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T266 43211-43219 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T267 43898-43906 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T268 43910-43918 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T269 43928-43936 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T270 44158-44166 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T271 44988-44997 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T272 45316-45325 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T273 45723-45731 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T274 45740-45748 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T275 46336-46344 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T276 46349-46357 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T277 46461-46469 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T278 47239-47247 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T279 48911-48919 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T280 50803-50811 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T281 50944-50950 Disease denotes Cancer http://purl.obolibrary.org/obo/MONDO_0004992
T282 51030-51038 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T283 51460-51466 Disease denotes Cancer http://purl.obolibrary.org/obo/MONDO_0004992
T284 52034-52042 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T285 52086-52094 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T286 52453-52461 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T287 52513-52521 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T288 52543-52551 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T289 52574-52582 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T290 52602-52610 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T291 52630-52638 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T292 52995-53002 Disease denotes Allergy http://purl.obolibrary.org/obo/MONDO_0005271
T293 53007-53017 Disease denotes Infectious http://purl.obolibrary.org/obo/MONDO_0005550
T294 53136-53146 Disease denotes Infectious http://purl.obolibrary.org/obo/MONDO_0005550

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 121-124 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T2 230-235 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T3 320-325 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T4 427-432 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T5 497-503 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T6 557-558 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T7 607-609 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T8 610-612 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T9 610-612 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T10 674-679 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T11 805-806 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T12 996-1001 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T13 1186-1191 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T14 1403-1408 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T15 1419-1423 http://purl.obolibrary.org/obo/CLO_0001236 denotes 2, a
T16 1496-1501 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T17 1557-1562 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T18 1740-1741 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T19 1893-1899 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T20 2409-2410 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T21 2460-2462 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T22 2484-2485 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T23 2538-2539 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T24 2832-2835 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T25 2985-2997 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T26 3031-3032 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T27 3124-3128 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bats
T28 3174-3180 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T29 3208-3214 http://purl.obolibrary.org/obo/NCBITaxon_9837 denotes camels
T30 3328-3332 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bats
T31 3388-3395 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T32 3431-3433 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T33 3431-3433 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T34 3614-3618 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bats
T35 3623-3629 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T36 3783-3789 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T37 3840-3844 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bats
T38 4021-4023 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T39 4021-4023 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T40 4313-4319 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T41 4431-4436 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T42 4490-4495 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T43 4712-4716 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T44 4727-4729 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T45 4776-4785 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membranes
T46 4787-4789 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T47 4787-4789 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T48 4856-4858 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T49 4863-4865 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T50 4863-4865 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T51 5142-5144 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T52 5257-5265 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T53 5275-5277 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T54 5275-5277 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T55 5403-5407 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T56 5541-5543 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T57 5541-5543 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T58 5593-5600 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T59 5664-5667 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T60 5685-5693 http://purl.obolibrary.org/obo/CLO_0001658 denotes activate
T61 5710-5718 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T62 5936-5937 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T63 5981-5986 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T64 5990-5991 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T65 6118-6123 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T66 6124-6128 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T67 6193-6195 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T68 6217-6218 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T69 6302-6307 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T70 6362-6363 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T71 6456-6460 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T72 6502-6507 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T73 6610-6611 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T74 6672-6674 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T75 6672-6674 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T76 6759-6760 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T77 6994-6999 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T78 7039-7043 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T79 7045-7047 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T80 7045-7047 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T81 7063-7065 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T82 7063-7065 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T83 7093-7097 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T84 7202-7207 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T85 7287-7292 http://purl.obolibrary.org/obo/CLO_0009985 denotes focus
T86 7574-7578 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T87 7636-7641 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T88 7676-7683 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T89 8110-8111 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T90 8186-8194 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T91 8202-8212 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T92 8307-8312 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T93 8333-8334 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T94 8417-8422 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T95 8671-8677 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T96 8780-8782 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T97 8783-8785 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T98 8783-8785 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T99 8849-8850 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T100 8878-8883 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T101 9021-9026 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T102 9076-9081 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T103 9141-9148 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T104 9182-9187 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T105 9490-9495 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T106 9549-9554 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T107 9583-9590 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T108 9898-9901 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T109 10039-10043 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bats
T110 10246-10249 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T111 10288-10289 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T112 10630-10632 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T113 10630-10632 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T114 10648-10650 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T115 10648-10650 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T116 10665-10667 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T117 10665-10667 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T118 10800-10808 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T119 10840-10842 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T120 10843-10845 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T121 10843-10845 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T122 10857-10859 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T123 10857-10859 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T124 11095-11100 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T125 11107-11108 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T126 11125-11130 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T127 11254-11259 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T128 11336-11348 http://purl.obolibrary.org/obo/CLO_0051719 denotes VeroE6 cells
T129 11487-11492 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T130 11516-11517 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T131 11577-11583 http://purl.obolibrary.org/obo/NCBITaxon_9479 denotes monkey
T132 11662-11667 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T133 11832-11833 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T134 11996-11997 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T135 12036-12037 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T136 12121-12133 http://purl.obolibrary.org/obo/CLO_0051719 denotes VeroE6 cells
T137 12212-12213 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T138 12288-12293 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T139 12413-12414 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T140 12658-12660 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T141 12661-12663 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T142 12661-12663 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T143 12799-12817 http://purl.obolibrary.org/obo/CHEBI_33708 denotes amino acid residue
T144 12799-12817 http://purl.obolibrary.org/obo/PR_000036907 denotes amino acid residue
T145 12940-12942 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T146 13064-13066 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T147 13126-13127 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T148 13133-13151 http://purl.obolibrary.org/obo/CHEBI_33708 denotes amino acid residue
T149 13133-13151 http://purl.obolibrary.org/obo/PR_000036907 denotes amino acid residue
T150 13190-13192 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T151 13197-13199 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T152 13197-13199 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T153 13299-13300 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T154 13322-13323 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T155 13554-13556 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T156 13557-13559 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T157 13557-13559 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T158 13596-13601 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T159 13840-13842 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T160 13843-13845 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T161 13843-13845 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T162 13908-13926 http://purl.obolibrary.org/obo/CHEBI_33708 denotes amino acid residue
T163 13908-13926 http://purl.obolibrary.org/obo/PR_000036907 denotes amino acid residue
T164 14193-14195 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T165 14196-14198 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T166 14196-14198 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T167 14330-14332 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T168 14333-14335 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T169 14333-14335 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T170 14359-14360 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T171 14368-14372 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T172 14716-14728 http://purl.obolibrary.org/obo/CLO_0051719 denotes VeroE6 cells
T173 14888-14893 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T174 14934-14936 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T175 14937-14939 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T176 14937-14939 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T177 15103-15104 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T178 15390-15397 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T179 15727-15729 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T180 15727-15729 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T181 15744-15746 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T182 15744-15746 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T183 16004-16006 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T184 16004-16006 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T185 16239-16241 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T186 16239-16241 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T187 16738-16741 http://purl.obolibrary.org/obo/CLO_0001236 denotes 2 A
T188 17057-17059 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T189 17115-17119 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T190 17121-17123 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T191 17121-17123 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T192 17384-17386 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T193 17384-17386 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T194 18274-18275 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T195 18378-18380 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T196 18704-18710 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T197 18791-18792 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T198 18797-18798 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T199 18895-18896 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T200 18914-18915 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T201 19058-19059 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T202 19089-19090 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T203 19091-19094 http://purl.obolibrary.org/obo/CLO_0053733 denotes 1:1
T204 19388-19389 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T205 19509-19516 http://purl.obolibrary.org/obo/CLO_0007225 denotes labeled
T206 19522-19523 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T207 19544-19546 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T208 19704-19707 http://purl.obolibrary.org/obo/CLO_0009946 denotes kon
T209 19709-19712 http://purl.obolibrary.org/obo/CLO_0007437 denotes M−1
T210 19709-19712 http://purl.obolibrary.org/obo/CLO_0007448 denotes M−1
T211 19709-19712 http://purl.obolibrary.org/obo/CLO_0007449 denotes M−1
T212 19709-19712 http://purl.obolibrary.org/obo/CLO_0050175 denotes M−1
T213 19709-19712 http://purl.obolibrary.org/obo/CLO_0052399 denotes M−1
T214 19713-19716 http://purl.obolibrary.org/obo/CLO_0050050 denotes s−1
T215 19780-19783 http://purl.obolibrary.org/obo/CLO_0050050 denotes s−1
T216 19914-19916 http://purl.obolibrary.org/obo/CLO_0001236 denotes 2A
T217 20217-20218 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T218 20292-20294 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T219 20295-20297 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T220 20295-20297 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T221 20468-20472 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T222 20502-20503 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T223 20727-20739 http://purl.obolibrary.org/obo/OBI_0000245 denotes organization
T224 20769-20771 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T225 20861-20862 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T226 20984-20985 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T227 21056-21057 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T228 21452-21456 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T229 21494-21498 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T230 21554-21555 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T231 21623-21624 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T232 21715-21716 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T233 21748-21749 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T234 21772-21773 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T235 21781-21783 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T236 21792-21794 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T237 21801-21803 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T238 21801-21803 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T239 22001-22003 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T240 22292-22293 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T241 22298-22299 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T242 22317-22318 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T243 22406-22408 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T244 22406-22408 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T245 22409-22410 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T246 22456-22460 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T247 22475-22479 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T248 22583-22584 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T249 22639-22640 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T250 22684-22685 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T251 23009-23011 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T252 23016-23018 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T253 23016-23018 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T254 23027-23029 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T255 23089-23093 http://purl.obolibrary.org/obo/CLO_0001302 denotes 3, 4
T256 23101-23102 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T257 23103-23104 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T258 23142-23143 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T259 23165-23166 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T260 23511-23513 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T261 23511-23513 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T262 23589-23593 http://purl.obolibrary.org/obo/CLO_0001302 denotes 3, 4
T263 23638-23639 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T264 23716-23717 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T265 23732-23738 http://purl.obolibrary.org/obo/CLO_0009859 denotes (E) S1
T266 23785-23787 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T267 23785-23787 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T268 23915-23919 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T269 23976-23980 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T270 24092-24094 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T271 24103-24106 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T272 24107-24108 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T273 24307-24309 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T274 24307-24309 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T275 24376-24377 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T276 24474-24478 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T277 24556-24558 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T278 24556-24558 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T279 24566-24574 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T280 24638-24642 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T281 24727-24731 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T282 24804-24806 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T283 24804-24806 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T284 24910-24911 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T285 25043-25050 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T286 25199-25206 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T287 25361-25368 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T288 25604-25608 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T289 25844-25846 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T290 26180-26182 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T291 26308-26310 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T292 26344-26346 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T293 26344-26346 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T294 26417-26419 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T295 26417-26419 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T296 26598-26605 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T297 26624-26626 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T298 26638-26650 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T299 26689-26690 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T300 26759-26760 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T301 26867-26869 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T302 27398-27399 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T303 27542-27544 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T304 27721-27723 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T305 27721-27723 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T306 27768-27770 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T307 27933-27940 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T308 28042-28044 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T309 28147-28148 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T310 28192-28205 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T311 28297-28302 http://purl.obolibrary.org/obo/GO_0005623 denotes Cells
T312 28304-28305 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T313 28310-28311 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T314 28427-28428 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T315 28439-28440 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T316 28486-28488 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T317 28577-28579 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T318 28671-28676 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T319 28695-28701 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T320 28780-28787 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T321 28867-28872 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T322 28915-28921 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T323 28952-28953 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T324 29043-29048 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T325 29059-29065 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T326 29182-29194 http://purl.obolibrary.org/obo/CLO_0051719 denotes VeroE6 cells
T327 29227-29228 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T328 29297-29302 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T329 29471-29476 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T330 29557-29564 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T331 29643-29644 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T332 29669-29673 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T333 29790-29795 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T334 29837-29843 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T335 29845-29847 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T336 29845-29847 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T337 29978-29984 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T338 30083-30084 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T339 30181-30183 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T340 30181-30183 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T341 30252-30258 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T342 30360-30365 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T343 30371-30378 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animals
T344 30382-30388 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T345 30390-30392 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T346 30390-30392 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T347 30400-30402 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T348 30400-30402 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T349 30504-30505 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T350 30603-30609 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T351 30653-30658 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T352 30662-30667 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T353 30730-30734 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T354 30818-30820 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T355 30821-30823 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T356 30821-30823 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T357 30832-30834 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T358 30832-30834 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T359 30979-30982 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T360 31005-31016 http://purl.obolibrary.org/obo/CLO_0053065 denotes human cells
T361 31087-31097 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T362 31106-31109 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T363 31110-31115 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T364 31133-31144 http://purl.obolibrary.org/obo/CLO_0053065 denotes human cells
T365 31179-31184 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T366 31262-31263 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T367 31288-31290 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T368 31291-31293 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T369 31291-31293 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T370 31410-31421 http://purl.obolibrary.org/obo/CLO_0053065 denotes human cells
T371 31460-31461 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T372 31537-31538 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T373 31594-31601 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T374 31635-31640 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T375 31718-31719 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T376 31747-31749 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T377 31750-31752 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T378 31750-31752 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T379 31819-31820 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T380 31914-31915 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T381 31926-31928 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T382 31929-31931 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T383 31929-31931 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T384 31977-31982 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T385 32242-32246 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T386 32576-32580 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T387 32662-32666 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T388 32704-32708 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T389 32963-32970 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T390 33044-33048 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T391 33165-33170 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T392 33319-33321 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T393 33319-33321 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T394 33599-33601 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T395 33599-33601 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T396 33753-33755 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T397 33837-33839 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T398 33837-33839 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T399 33903-33912 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membranes
T400 34027-34032 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T401 34127-34132 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T402 34380-34382 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T403 34380-34382 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T404 34397-34399 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T405 34397-34399 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T406 34796-34803 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T407 34841-34846 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T408 35009-35014 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T409 35073-35075 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T410 35073-35075 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T411 35106-35113 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T412 36091-36092 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T413 36335-36342 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T414 36358-36364 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T415 36577-36581 http://purl.obolibrary.org/obo/NCBITaxon_9925 denotes Goat
T416 36587-36596 http://purl.obolibrary.org/obo/CLO_0053695 denotes Human IgG
T417 36713-36721 http://purl.obolibrary.org/obo/PR_000018263 denotes Peptides
T418 36825-36828 http://purl.obolibrary.org/obo/CLO_0001230 denotes 293
T419 36825-36828 http://purl.obolibrary.org/obo/CLO_0037237 denotes 293
T420 36825-36828 http://purl.obolibrary.org/obo/CLO_0050903 denotes 293
T421 36825-36828 http://purl.obolibrary.org/obo/CLO_0054249 denotes 293
T422 36825-36828 http://purl.obolibrary.org/obo/CLO_0054250 denotes 293
T423 36825-36828 http://purl.obolibrary.org/obo/CLO_0054251 denotes 293
T424 36825-36828 http://purl.obolibrary.org/obo/CLO_0054252 denotes 293
T425 37137-37147 http://purl.obolibrary.org/obo/CLO_0000031 denotes Cell Lines
T426 37158-37164 http://purl.obolibrary.org/obo/CLO_0001230 denotes HEK293
T427 37252-37263 http://purl.obolibrary.org/obo/CLO_0009527 denotes Vero(C1008)
T428 37319-37326 http://purl.obolibrary.org/obo/NCBITaxon_10026 denotes Hamster
T429 37327-37333 http://purl.obolibrary.org/obo/UBERON_0002113 denotes Kidney
T430 37327-37333 http://www.ebi.ac.uk/efo/EFO_0000927 denotes Kidney
T431 37327-37333 http://www.ebi.ac.uk/efo/EFO_0000929 denotes Kidney
T432 37443-37444 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T433 37476-37477 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T434 37514-37515 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T435 37551-37552 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T436 37613-37614 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T437 37690-37691 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T438 37713-37718 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T439 37756-37757 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T440 37802-37803 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T441 37927-37931 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T442 38566-38569 http://purl.obolibrary.org/obo/CLO_0050167 denotes LLC
T443 38604-38609 http://purl.obolibrary.org/obo/CLO_0007225 denotes label
T444 38691-38694 http://purl.obolibrary.org/obo/CLO_0050167 denotes LLC
T445 38701-38703 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T446 38798-38799 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T447 38800-38802 http://purl.obolibrary.org/obo/CLO_0003797 denotes HP
T448 38800-38802 http://purl.obolibrary.org/obo/PR_000008725 denotes HP
T449 39274-39275 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T450 39456-39466 http://purl.obolibrary.org/obo/CLO_0000031 denotes Cell lines
T451 39478-39479 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T452 39480-39486 http://purl.obolibrary.org/obo/UBERON_0003100 denotes female
T453 39487-39492 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T454 39493-39509 http://www.ebi.ac.uk/efo/EFO_0000927 denotes embryonic kidney
T455 39510-39519 http://purl.obolibrary.org/obo/CLO_0000031 denotes cell line
T456 39595-39600 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T457 39723-39724 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T458 39725-39731 http://purl.obolibrary.org/obo/UBERON_0003100 denotes female
T459 39732-39737 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T460 39738-39754 http://www.ebi.ac.uk/efo/EFO_0000927 denotes embryonic kidney
T461 39755-39764 http://purl.obolibrary.org/obo/CLO_0000031 denotes cell line
T462 39783-39784 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T463 39785-39791 http://purl.obolibrary.org/obo/UBERON_0003100 denotes female
T464 39792-39798 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T465 39792-39798 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T466 39792-39798 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T467 39799-39809 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T468 39810-39814 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T469 39834-39840 http://purl.obolibrary.org/obo/NCBITaxon_9479 denotes monkey
T470 39849-39850 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T471 39851-39857 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T472 39851-39857 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T473 39851-39857 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T474 39858-39867 http://purl.obolibrary.org/obo/CLO_0000031 denotes cell line
T475 39878-39886 http://purl.obolibrary.org/obo/NCBITaxon_10026 denotes hamsters
T476 39901-39906 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T477 40001-40012 http://purl.obolibrary.org/obo/CLO_0000031 denotes Cells lines
T478 40022-40028 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T479 40187-40188 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T480 40286-40287 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T481 40345-40351 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T482 40352-40359 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T483 40364-40365 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T484 40603-40609 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T485 40610-40617 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T486 40622-40623 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T487 40798-40803 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T488 40840-40843 http://purl.obolibrary.org/obo/CLO_0001230 denotes 293
T489 40840-40843 http://purl.obolibrary.org/obo/CLO_0037237 denotes 293
T490 40840-40843 http://purl.obolibrary.org/obo/CLO_0050903 denotes 293
T491 40840-40843 http://purl.obolibrary.org/obo/CLO_0054249 denotes 293
T492 40840-40843 http://purl.obolibrary.org/obo/CLO_0054250 denotes 293
T493 40840-40843 http://purl.obolibrary.org/obo/CLO_0054251 denotes 293
T494 40840-40843 http://purl.obolibrary.org/obo/CLO_0054252 denotes 293
T495 40893-40894 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T496 40980-40983 http://purl.obolibrary.org/obo/CLO_0001230 denotes 293
T497 40980-40983 http://purl.obolibrary.org/obo/CLO_0037237 denotes 293
T498 40980-40983 http://purl.obolibrary.org/obo/CLO_0050903 denotes 293
T499 40980-40983 http://purl.obolibrary.org/obo/CLO_0054249 denotes 293
T500 40980-40983 http://purl.obolibrary.org/obo/CLO_0054250 denotes 293
T501 40980-40983 http://purl.obolibrary.org/obo/CLO_0054251 denotes 293
T502 40980-40983 http://purl.obolibrary.org/obo/CLO_0054252 denotes 293
T503 41027-41032 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T504 41042-41043 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T505 41065-41070 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T506 41097-41100 http://purl.obolibrary.org/obo/CLO_0001302 denotes 3–4
T507 41143-41148 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T508 41173-41176 http://purl.obolibrary.org/obo/CLO_0001302 denotes 3–4
T509 41263-41264 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T510 41335-41336 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T511 41504-41509 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T512 41587-41589 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T513 41600-41609 http://purl.obolibrary.org/obo/CLO_0053695 denotes human IgG
T514 41695-41697 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T515 41783-41788 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T516 41825-41828 http://purl.obolibrary.org/obo/CLO_0001230 denotes 293
T517 41825-41828 http://purl.obolibrary.org/obo/CLO_0037237 denotes 293
T518 41825-41828 http://purl.obolibrary.org/obo/CLO_0050903 denotes 293
T519 41825-41828 http://purl.obolibrary.org/obo/CLO_0054249 denotes 293
T520 41825-41828 http://purl.obolibrary.org/obo/CLO_0054250 denotes 293
T521 41825-41828 http://purl.obolibrary.org/obo/CLO_0054251 denotes 293
T522 41825-41828 http://purl.obolibrary.org/obo/CLO_0054252 denotes 293
T523 41878-41879 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T524 41965-41968 http://purl.obolibrary.org/obo/CLO_0001230 denotes 293
T525 41965-41968 http://purl.obolibrary.org/obo/CLO_0037237 denotes 293
T526 41965-41968 http://purl.obolibrary.org/obo/CLO_0050903 denotes 293
T527 41965-41968 http://purl.obolibrary.org/obo/CLO_0054249 denotes 293
T528 41965-41968 http://purl.obolibrary.org/obo/CLO_0054250 denotes 293
T529 41965-41968 http://purl.obolibrary.org/obo/CLO_0054251 denotes 293
T530 41965-41968 http://purl.obolibrary.org/obo/CLO_0054252 denotes 293
T531 42012-42017 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T532 42027-42028 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T533 42050-42055 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T534 42126-42131 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T535 42341-42342 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T536 42351-42352 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T537 42426-42427 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T538 42534-42536 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T539 42577-42578 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T540 42632-42634 http://purl.obolibrary.org/obo/CLO_0052676 denotes FC
T541 42791-42792 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T542 42801-42802 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T543 42846-42848 http://purl.obolibrary.org/obo/CLO_0052676 denotes Fc
T544 42919-42920 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T545 42986-42987 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T546 43319-43324 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T547 43490-43491 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T548 43559-43564 http://purl.obolibrary.org/obo/GO_0005623 denotes Cells
T549 43622-43627 http://purl.obolibrary.org/obo/GO_0005623 denotes Cells
T550 43784-43793 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membranes
T551 43813-43814 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T552 43821-43829 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T553 44067-44068 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T554 44130-44131 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T555 44137-44145 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T556 44155-44157 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T557 44155-44157 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T558 44248-44252 http://purl.obolibrary.org/obo/NCBITaxon_9925 denotes goat
T559 44258-44263 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T560 44267-44272 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T561 44390-44391 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T562 44392-44394 http://purl.obolibrary.org/obo/CLO_0007314 denotes LI
T563 44478-44483 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T564 44535-44547 http://purl.obolibrary.org/obo/CLO_0051719 denotes VeroE6 cells
T565 44583-44584 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T566 44620-44625 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T567 44953-44958 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T568 44963-44965 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T569 44983-44985 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T570 45037-45042 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T571 45131-45132 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T572 45219-45225 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T573 45378-45383 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T574 45546-45556 http://purl.obolibrary.org/obo/OBI_0000968 denotes instrument
T575 45661-45662 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T576 45954-45955 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T577 46130-46131 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T578 46132-46135 http://purl.obolibrary.org/obo/CLO_0053733 denotes 1:1
T579 46196-46199 http://purl.obolibrary.org/obo/CLO_0009946 denotes kon
T580 46234-46235 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T581 46544-46549 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T582 46586-46589 http://purl.obolibrary.org/obo/CLO_0001230 denotes 293
T583 46586-46589 http://purl.obolibrary.org/obo/CLO_0037237 denotes 293
T584 46586-46589 http://purl.obolibrary.org/obo/CLO_0050903 denotes 293
T585 46586-46589 http://purl.obolibrary.org/obo/CLO_0054249 denotes 293
T586 46586-46589 http://purl.obolibrary.org/obo/CLO_0054250 denotes 293
T587 46586-46589 http://purl.obolibrary.org/obo/CLO_0054251 denotes 293
T588 46586-46589 http://purl.obolibrary.org/obo/CLO_0054252 denotes 293
T589 46639-46640 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T590 46764-46769 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T591 46779-46780 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T592 46802-46807 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T593 46880-46885 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T594 46988-46989 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T595 47093-47094 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T596 47268-47269 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T597 47333-47334 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T598 47409-47410 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T599 47459-47460 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T600 47694-47695 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T601 47702-47704 http://purl.obolibrary.org/obo/CLO_0037127 denotes K2
T602 47797-47798 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T603 47879-47880 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T604 47920-47921 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T605 47942-47943 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T606 48079-48081 http://purl.obolibrary.org/obo/CLO_0007874 denotes ms
T607 48119-48120 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T608 48141-48142 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T609 48431-48432 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T610 48472-48473 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T611 48493-48494 http://purl.obolibrary.org/obo/CLO_0001020 denotes Å
T612 48858-48862 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T613 50045-50047 http://purl.obolibrary.org/obo/CLO_0051741 denotes C1
T614 50220-50221 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T615 50674-50676 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T616 50739-50743 http://purl.obolibrary.org/obo/CLO_0001185 denotes 2018
T617 50985-50986 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T618 51219-51223 http://purl.obolibrary.org/obo/UBERON_0002415 denotes tail
T619 51305-51311 http://purl.obolibrary.org/obo/UBERON_0001969 denotes Plasma
T620 51327-51334 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animals
T621 51391-51394 http://purl.obolibrary.org/obo/CLO_0001387 denotes 4°C
T622 51519-51525 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes Animal
T623 52118-52119 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T624 52229-52231 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T625 52303-52307 http://purl.obolibrary.org/obo/CLO_0001302 denotes 3, 4
T626 52320-52322 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T627 53056-53057 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T628 53557-53563 http://purl.obolibrary.org/obo/OBI_0000968 denotes device

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 62-74 Chemical denotes Glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T2 197-210 Chemical denotes glycoproteins http://purl.obolibrary.org/obo/CHEBI_17089
T3 536-548 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T4 610-612 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T5 742-744 Chemical denotes EM http://purl.obolibrary.org/obo/CHEBI_73507
T6 848-858 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T7 1290-1302 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T8 1569-1571 Chemical denotes EM http://purl.obolibrary.org/obo/CHEBI_73507
T9 1607-1619 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T10 3397-3399 Chemical denotes Ge http://purl.obolibrary.org/obo/CHEBI_30441
T11 3431-3433 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T12 3987-3989 Chemical denotes Ge http://purl.obolibrary.org/obo/CHEBI_30441
T13 4021-4023 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T14 4539-4551 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T15 4787-4789 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T16 4863-4865 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T17 5275-5277 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T18 5541-5543 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T19 5593-5600 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T20 5698-5705 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T21 6099-6106 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T22 6365-6367 Chemical denotes SA http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801
T26 6376-6382 Chemical denotes acetyl http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887
T28 6387-6393 Chemical denotes acetyl http://purl.obolibrary.org/obo/CHEBI_40574|http://purl.obolibrary.org/obo/CHEBI_46887
T30 6414-6427 Chemical denotes glycoproteins http://purl.obolibrary.org/obo/CHEBI_17089
T31 6432-6443 Chemical denotes glycolipids http://purl.obolibrary.org/obo/CHEBI_33563
T32 6672-6674 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T33 6813-6815 Chemical denotes Lu http://purl.obolibrary.org/obo/CHEBI_33382
T34 6932-6943 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T35 7001-7003 Chemical denotes Ge http://purl.obolibrary.org/obo/CHEBI_30441
T36 7045-7047 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T37 7063-7065 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T38 7141-7153 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T39 7378-7385 Chemical denotes glycans http://purl.obolibrary.org/obo/CHEBI_18154
T40 8783-8785 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T41 9276-9278 Chemical denotes EM http://purl.obolibrary.org/obo/CHEBI_73507
T42 9796-9808 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T43 9820-9830 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T44 9820-9825 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T45 9826-9830 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T46 9931-9943 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T47 10111-10113 Chemical denotes Ge http://purl.obolibrary.org/obo/CHEBI_30441
T48 10347-10360 Chemical denotes glycoproteins http://purl.obolibrary.org/obo/CHEBI_17089
T49 10371-10381 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T50 10371-10376 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T51 10377-10381 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T52 10469-10471 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T53 10520-10530 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T54 10520-10525 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T55 10526-10530 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T56 10630-10632 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T57 10648-10650 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T58 10665-10667 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T59 10843-10845 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T60 10857-10859 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T61 12613-12626 Chemical denotes glycoproteins http://purl.obolibrary.org/obo/CHEBI_17089
T62 12661-12663 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T63 12799-12817 Chemical denotes amino acid residue http://purl.obolibrary.org/obo/CHEBI_33708
T64 12799-12809 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T65 12799-12804 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T66 12805-12809 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T67 13133-13151 Chemical denotes amino acid residue http://purl.obolibrary.org/obo/CHEBI_33708
T68 13133-13143 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T69 13133-13138 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T70 13139-13143 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T71 13197-13199 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T72 13557-13559 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T73 13843-13845 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T74 13908-13913 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T75 13914-13918 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T76 14111-14127 Chemical denotes arginine residue http://purl.obolibrary.org/obo/CHEBI_32700
T77 14111-14119 Chemical denotes arginine http://purl.obolibrary.org/obo/CHEBI_16467|http://purl.obolibrary.org/obo/CHEBI_29016|http://purl.obolibrary.org/obo/CHEBI_32696
T80 14196-14198 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T81 14333-14335 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T82 14937-14939 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T83 15143-15155 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T84 15727-15729 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T85 15744-15746 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T86 16004-16006 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T87 16239-16241 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T88 17121-17123 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T89 17384-17386 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T90 18621-18634 Chemical denotes glycoproteins http://purl.obolibrary.org/obo/CHEBI_17089
T91 18963-18970 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T92 19312-19322 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T93 19312-19317 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T94 19318-19322 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T95 19676-19678 Chemical denotes KD http://purl.obolibrary.org/obo/CHEBI_73601
T96 20030-20037 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T97 20111-20123 Chemical denotes Glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T98 20162-20164 Chemical denotes EM http://purl.obolibrary.org/obo/CHEBI_73507
T99 20191-20203 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T100 20295-20297 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T101 20416-20423 Chemical denotes proline http://purl.obolibrary.org/obo/CHEBI_17203|http://purl.obolibrary.org/obo/CHEBI_26271
T103 20621-20623 Chemical denotes EM http://purl.obolibrary.org/obo/CHEBI_73507
T104 21801-21803 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T105 21871-21873 Chemical denotes SA http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801
T109 22406-22408 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T110 22535-22537 Chemical denotes EM http://purl.obolibrary.org/obo/CHEBI_73507
T111 22569-22581 Chemical denotes Glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T112 22630-22632 Chemical denotes EM http://purl.obolibrary.org/obo/CHEBI_73507
T113 22810-22812 Chemical denotes EM http://purl.obolibrary.org/obo/CHEBI_73507
T114 22958-22965 Chemical denotes glycans http://purl.obolibrary.org/obo/CHEBI_18154
T115 23016-23018 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T116 23035-23037 Chemical denotes EM http://purl.obolibrary.org/obo/CHEBI_73507
T117 23121-23129 Chemical denotes electron http://purl.obolibrary.org/obo/CHEBI_10545
T118 23231-23235 Chemical denotes Gold http://purl.obolibrary.org/obo/CHEBI_29287
T119 23511-23513 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T120 23785-23787 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T121 23839-23852 Chemical denotes glycoproteins http://purl.obolibrary.org/obo/CHEBI_17089
T122 24307-24309 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T123 24556-24558 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T124 24804-24806 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T125 25043-25050 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T126 25199-25206 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T127 25443-25456 Chemical denotes glycoproteins http://purl.obolibrary.org/obo/CHEBI_17089
T128 25505-25512 Chemical denotes glycans http://purl.obolibrary.org/obo/CHEBI_18154
T129 25617-25633 Chemical denotes oligosaccharides http://purl.obolibrary.org/obo/CHEBI_50699
T130 25895-25911 Chemical denotes oligosaccharides http://purl.obolibrary.org/obo/CHEBI_50699
T131 25937-25939 Chemical denotes EM http://purl.obolibrary.org/obo/CHEBI_73507
T132 26293-26300 Chemical denotes glycans http://purl.obolibrary.org/obo/CHEBI_18154
T133 26329-26336 Chemical denotes glycans http://purl.obolibrary.org/obo/CHEBI_18154
T134 26344-26346 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T135 26417-26419 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T136 26491-26504 Chemical denotes glycoproteins http://purl.obolibrary.org/obo/CHEBI_17089
T137 26774-26781 Chemical denotes glycans http://purl.obolibrary.org/obo/CHEBI_18154
T138 26803-26805 Chemical denotes EM http://purl.obolibrary.org/obo/CHEBI_73507
T139 27505-27507 Chemical denotes EM http://purl.obolibrary.org/obo/CHEBI_73507
T140 27721-27723 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T141 27820-27822 Chemical denotes SA http://purl.obolibrary.org/obo/CHEBI_35962|http://purl.obolibrary.org/obo/CHEBI_38358|http://purl.obolibrary.org/obo/CHEBI_45373|http://purl.obolibrary.org/obo/CHEBI_74801
T145 27846-27848 Chemical denotes 5B http://purl.obolibrary.org/obo/CHEBI_27560
T146 27969-27971 Chemical denotes Ge http://purl.obolibrary.org/obo/CHEBI_30441
T147 28353-28366 Chemical denotes glycoproteins http://purl.obolibrary.org/obo/CHEBI_17089
T148 29416-29423 Chemical denotes glycans http://purl.obolibrary.org/obo/CHEBI_18154
T149 29845-29847 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T150 30181-30183 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T151 30390-30392 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T152 30400-30402 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T153 30763-30775 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T154 30821-30823 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T155 30832-30834 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T156 31291-31293 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T157 31750-31752 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T158 31929-31931 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T159 33319-33321 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T160 33384-33391 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T161 33599-33601 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T162 33756-33761 Chemical denotes crown http://purl.obolibrary.org/obo/CHEBI_37409
T163 33837-33839 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T164 33979-33991 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T165 34380-34382 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T166 34397-34399 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T167 34503-34515 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T168 34731-34744 Chemical denotes glycoproteins http://purl.obolibrary.org/obo/CHEBI_17089
T169 35073-35075 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T170 35106-35113 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T171 35715-35725 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T172 35715-35720 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T173 35721-35725 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T174 36169-36182 Chemical denotes glycoproteins http://purl.obolibrary.org/obo/CHEBI_17089
T175 36748-36756 Chemical denotes Thrombin http://purl.obolibrary.org/obo/CHEBI_9574
T176 37350-37353 Chemical denotes CCL http://purl.obolibrary.org/obo/CHEBI_3478
T177 37382-37385 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T178 38604-38609 Chemical denotes label http://purl.obolibrary.org/obo/CHEBI_35209
T179 38790-38797 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T180 38800-38802 Chemical denotes HP http://purl.obolibrary.org/obo/CHEBI_74055
T181 38803-38805 Chemical denotes GE http://purl.obolibrary.org/obo/CHEBI_73801
T182 38863-38865 Chemical denotes GE http://purl.obolibrary.org/obo/CHEBI_73801
T183 38923-38929 Chemical denotes Carbon http://purl.obolibrary.org/obo/CHEBI_27594
T184 38940-38942 Chemical denotes Cu http://purl.obolibrary.org/obo/CHEBI_28694
T185 39076-39084 Chemical denotes reagents http://purl.obolibrary.org/obo/CHEBI_33893
T186 39200-39208 Chemical denotes reagents http://purl.obolibrary.org/obo/CHEBI_33893
T187 39692-39695 Chemical denotes CO2 http://purl.obolibrary.org/obo/CHEBI_16526
T188 39937-39940 Chemical denotes CO2 http://purl.obolibrary.org/obo/CHEBI_16526
T189 39976-39986 Chemical denotes penicillin http://purl.obolibrary.org/obo/CHEBI_17334|http://purl.obolibrary.org/obo/CHEBI_51356
T191 39987-39999 Chemical denotes streptomycin http://purl.obolibrary.org/obo/CHEBI_17076|http://purl.obolibrary.org/obo/CHEBI_58007
T193 40352-40359 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T194 40382-40391 Chemical denotes histidine http://purl.obolibrary.org/obo/CHEBI_27570
T195 40610-40617 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T196 40640-40649 Chemical denotes histidine http://purl.obolibrary.org/obo/CHEBI_27570
T197 40909-40912 Chemical denotes CO2 http://purl.obolibrary.org/obo/CHEBI_16526
T198 41002-41009 Chemical denotes reagent http://purl.obolibrary.org/obo/CHEBI_33893
T199 41269-41275 Chemical denotes Cobalt http://purl.obolibrary.org/obo/CHEBI_27638|http://purl.obolibrary.org/obo/CHEBI_34631
T201 41337-41343 Chemical denotes buffer http://purl.obolibrary.org/obo/CHEBI_35225
T202 41361-41365 Chemical denotes Tris http://purl.obolibrary.org/obo/CHEBI_9754
T203 41384-41388 Chemical denotes NaCl http://purl.obolibrary.org/obo/CHEBI_26710
T204 41408-41411 Chemical denotes SDS http://purl.obolibrary.org/obo/CHEBI_8984
T205 41510-41521 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T206 41894-41897 Chemical denotes CO2 http://purl.obolibrary.org/obo/CHEBI_16526
T207 41987-41994 Chemical denotes reagent http://purl.obolibrary.org/obo/CHEBI_33893
T208 42343-42350 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T209 42361-42363 Chemical denotes GE http://purl.obolibrary.org/obo/CHEBI_73801
T210 42448-42450 Chemical denotes GL http://purl.obolibrary.org/obo/CHEBI_73514
T211 42459-42461 Chemical denotes GE http://purl.obolibrary.org/obo/CHEBI_73801
T212 42499-42503 Chemical denotes Tris http://purl.obolibrary.org/obo/CHEBI_9754
T213 42504-42507 Chemical denotes HCl http://purl.obolibrary.org/obo/CHEBI_17883
T214 42524-42528 Chemical denotes NaCl http://purl.obolibrary.org/obo/CHEBI_26710
T215 42588-42595 Chemical denotes mixture http://purl.obolibrary.org/obo/CHEBI_60004
T216 42681-42684 Chemical denotes HCl http://purl.obolibrary.org/obo/CHEBI_17883
T217 42699-42703 Chemical denotes NaCl http://purl.obolibrary.org/obo/CHEBI_26710
T218 42715-42720 Chemical denotes CaCl2 http://purl.obolibrary.org/obo/CHEBI_3312
T219 42734-42741 Chemical denotes mixture http://purl.obolibrary.org/obo/CHEBI_60004
T220 42793-42800 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T221 42830-42837 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T222 42866-42873 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T223 42948-42950 Chemical denotes GL http://purl.obolibrary.org/obo/CHEBI_73514
T224 42952-42954 Chemical denotes GE http://purl.obolibrary.org/obo/CHEBI_73801
T225 42988-42994 Chemical denotes buffer http://purl.obolibrary.org/obo/CHEBI_35225
T226 43012-43016 Chemical denotes Tris http://purl.obolibrary.org/obo/CHEBI_9754
T227 43035-43039 Chemical denotes NaCl http://purl.obolibrary.org/obo/CHEBI_26710
T228 43054-43061 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T229 43981-43984 Chemical denotes SDS http://purl.obolibrary.org/obo/CHEBI_8984
T230 43993-43999 Chemical denotes buffer http://purl.obolibrary.org/obo/CHEBI_35225
T231 44085-44089 Chemical denotes Tris http://purl.obolibrary.org/obo/CHEBI_9754
T232 44090-44097 Chemical denotes Glycine http://purl.obolibrary.org/obo/CHEBI_15428
T233 44155-44157 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T234 44227-44232 Chemical denotes Fluor http://purl.obolibrary.org/obo/CHEBI_24061
T235 44392-44394 Chemical denotes LI http://purl.obolibrary.org/obo/CHEBI_74540
T236 45635-45640 Chemical denotes water http://purl.obolibrary.org/obo/CHEBI_15377
T237 45696-45702 Chemical denotes buffer http://purl.obolibrary.org/obo/CHEBI_35225
T238 45874-45880 Chemical denotes buffer http://purl.obolibrary.org/obo/CHEBI_35225
T239 45918-45924 Chemical denotes buffer http://purl.obolibrary.org/obo/CHEBI_35225
T240 46421-46428 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T241 46655-46658 Chemical denotes CO2 http://purl.obolibrary.org/obo/CHEBI_16526
T242 46994-47000 Chemical denotes Cobalt http://purl.obolibrary.org/obo/CHEBI_27638|http://purl.obolibrary.org/obo/CHEBI_34631
T244 47036-47043 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T245 47095-47101 Chemical denotes buffer http://purl.obolibrary.org/obo/CHEBI_35225
T246 47119-47123 Chemical denotes Tris http://purl.obolibrary.org/obo/CHEBI_9754
T247 47142-47146 Chemical denotes NaCl http://purl.obolibrary.org/obo/CHEBI_26710
T248 47316-47322 Chemical denotes carbon http://purl.obolibrary.org/obo/CHEBI_27594|http://purl.obolibrary.org/obo/CHEBI_33415
T250 47371-47377 Chemical denotes carbon http://purl.obolibrary.org/obo/CHEBI_27594|http://purl.obolibrary.org/obo/CHEBI_33415
T252 47612-47617 Chemical denotes Titan http://purl.obolibrary.org/obo/CHEBI_33341
T253 47637-47645 Chemical denotes electron http://purl.obolibrary.org/obo/CHEBI_10545
T254 48197-48199 Chemical denotes EM http://purl.obolibrary.org/obo/CHEBI_73507
T255 49504-49508 Chemical denotes gold http://purl.obolibrary.org/obo/CHEBI_29287|http://purl.obolibrary.org/obo/CHEBI_30050
T67690 50062-50069 Chemical denotes glycans http://purl.obolibrary.org/obo/CHEBI_18154
T6636 50192-50198 Chemical denotes Glycan http://purl.obolibrary.org/obo/CHEBI_18154
T31572 50321-50331 Chemical denotes saccharide http://purl.obolibrary.org/obo/CHEBI_16646
T911 50637-50644 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T34610 51207-51211 Chemical denotes base http://purl.obolibrary.org/obo/CHEBI_22695
T97749 51962-51969 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T78557 52238-52240 Chemical denotes EM http://purl.obolibrary.org/obo/CHEBI_73507
T58566 52330-52334 Chemical denotes Acid http://purl.obolibrary.org/obo/CHEBI_37527
T3348 53692-53700 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T12139 53800-53802 Chemical denotes EM http://purl.obolibrary.org/obo/CHEBI_73507

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 4474-4489 http://purl.obolibrary.org/obo/GO_0044409 denotes entry into host
T2 5710-5725 http://purl.obolibrary.org/obo/GO_0061025 denotes membrane fusion
T3 6124-6135 http://purl.obolibrary.org/obo/GO_0140253 denotes cell fusion
T4 6124-6135 http://purl.obolibrary.org/obo/GO_0045026 denotes cell fusion
T5 6124-6135 http://purl.obolibrary.org/obo/GO_0000768 denotes cell fusion
T6 6124-6135 http://purl.obolibrary.org/obo/GO_0000747 denotes cell fusion
T7 7186-7201 http://purl.obolibrary.org/obo/GO_0044409 denotes entry into host
T8 7669-7675 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T9 8186-8201 http://purl.obolibrary.org/obo/GO_0061025 denotes membrane fusion
T10 8836-8848 http://purl.obolibrary.org/obo/GO_0009058 denotes biosynthesis
T11 9060-9067 http://purl.obolibrary.org/obo/GO_0009606 denotes tropism
T12 10800-10815 http://purl.obolibrary.org/obo/GO_0061025 denotes membrane fusion
T13 11279-11291 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T14 11749-11761 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T15 13572-13584 http://purl.obolibrary.org/obo/GO_0009058 denotes biosynthesis
T16 14655-14662 http://purl.obolibrary.org/obo/GO_0007114 denotes budding
T17 14689-14701 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T18 14851-14863 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T19 14958-14970 http://purl.obolibrary.org/obo/GO_0009058 denotes biosynthesis
T20 15198-15205 http://purl.obolibrary.org/obo/GO_0009606 denotes tropism
T21 15615-15632 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T22 15615-15632 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T23 18566-18578 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T24 24566-24581 http://purl.obolibrary.org/obo/GO_0061025 denotes membrane fusion
T25 25847-25869 http://purl.obolibrary.org/obo/GO_0006487 denotes N-linked glycosylation
T26 25856-25869 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T27 26018-26040 http://purl.obolibrary.org/obo/GO_0006487 denotes N-linked glycosylation
T28 26027-26040 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T29 26196-26218 http://purl.obolibrary.org/obo/GO_0006487 denotes N-linked glycosylation
T30 26205-26218 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T31 26420-26442 http://purl.obolibrary.org/obo/GO_0006487 denotes N-linked glycosylation
T32 26429-26442 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T33 26895-26917 http://purl.obolibrary.org/obo/GO_0006487 denotes N-Linked Glycosylation
T34 26904-26917 http://purl.obolibrary.org/obo/GO_0070085 denotes Glycosylation
T35 27400-27413 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T36 28281-28296 http://purl.obolibrary.org/obo/GO_0044409 denotes Entry into Host
T37 29087-29099 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T38 29147-29159 http://purl.obolibrary.org/obo/GO_0009293 denotes transduction
T39 29281-29296 http://purl.obolibrary.org/obo/GO_0044409 denotes entry into host
T40 29620-29635 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T41 29685-29692 http://purl.obolibrary.org/obo/GO_0009606 denotes tropism
T42 30879-30886 http://purl.obolibrary.org/obo/GO_0009606 denotes tropism
T43 31789-31801 http://purl.obolibrary.org/obo/GO_0009058 denotes biosynthesis
T44 32258-32265 http://purl.obolibrary.org/obo/GO_0009606 denotes tropism
T45 32486-32501 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T46 34300-34317 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T47 34300-34317 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T48 40333-40344 http://purl.obolibrary.org/obo/GO_0016791 denotes phosphatase
T49 40591-40602 http://purl.obolibrary.org/obo/GO_0016791 denotes phosphatase
T50 53120-53132 http://purl.obolibrary.org/obo/GO_0009405 denotes Pathogenesis

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-74 Sentence denotes Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
T2 76-84 Sentence denotes Abstract
T3 85-92 Sentence denotes Summary
T4 93-174 Sentence denotes The emergence of SARS-CoV-2 has resulted in >90,000 infections and >3,000 deaths.
T5 175-274 Sentence denotes Coronavirus spike (S) glycoproteins promote entry into cells and are the main target of antibodies.
T6 275-504 Sentence denotes We show that SARS-CoV-2 S uses ACE2 to enter cells and that the receptor-binding domains of SARS-CoV-2 S and SARS-CoV S bind with similar affinities to human ACE2, correlating with the efficient spread of SARS-CoV-2 among humans.
T7 505-722 Sentence denotes We found that the SARS-CoV-2 S glycoprotein harbors a furin cleavage site at the boundary between the S1/S2 subunits, which is processed during biogenesis and sets this virus apart from SARS-CoV and SARS-related CoVs.
T8 723-1113 Sentence denotes We determined cryo-EM structures of the SARS-CoV-2 S ectodomain trimer, providing a blueprint for the design of vaccines and inhibitors of viral entry. Finally, we demonstrate that SARS-CoV S murine polyclonal antibodies potently inhibited SARS-CoV-2 S mediated entry into cells, indicating that cross-neutralizing antibodies targeting conserved S epitopes can be elicited upon vaccination.
T9 1115-1133 Sentence denotes Graphical Abstract
T10 1135-1145 Sentence denotes Highlights
T11 1146-1191 Sentence denotes • SARS-CoV-2 uses ACE2 to enter target cells
T12 1192-1255 Sentence denotes • SARS-CoV-2 and SARS-CoV bind with similar affinities to ACE2
T13 1256-1323 Sentence denotes • Structures of SARS-CoV-2 spike glycoprotein in two conformations
T14 1324-1408 Sentence denotes • SARS-CoV polyclonal antibodies inhibit SARS-CoV-2 spike-mediated entry into cells
T15 1410-1563 Sentence denotes SARS-CoV-2, a newly emerged pathogen spreading worldwide, binds with high affinity to human ACE2 and uses it as an entry receptor to invade target cells.
T16 1564-1796 Sentence denotes Cryo-EM structures of the SARS-CoV-2 spike glycoprotein in two distinct conformations, along with inhibition of spike-mediated entry by SARS-CoV polyclonal antibodies, provide a blueprint for the design of vaccines and therapeutics.
T17 1798-1810 Sentence denotes Introduction
T18 1811-2175 Sentence denotes Three coronaviruses have crossed the species barrier to cause deadly pneumonia in humans since the beginning of the 21st century: severe acute respiratory syndrome coronavirus (SARS-CoV) (Drosten et al., 2003, Ksiazek et al., 2003), Middle-East respiratory syndrome coronavirus (Zaki et al., 2012) (MERS-CoV), and SARS-CoV-2 (Huang et al., 2020, Zhu et al., 2020).
T19 2176-2339 Sentence denotes SARS-CoV emerged in the Guangdong province of China in 2002 and spread to five continents through air travel routes, infecting 8,098 people and causing 774 deaths.
T20 2340-2537 Sentence denotes In 2012, MERS-CoV emerged in the Arabian Peninsula, where it remains a major public health concern, and was exported to 27 countries, infecting a total of ∼2,494 individuals and claiming 858 lives.
T21 2538-2741 Sentence denotes A previously unknown coronavirus, named SARS-CoV-2, was discovered in December 2019 in Wuhan, Hubei province of China and was sequenced and isolated by January 2020 (Zhou et al., 2020, Zhu et al., 2020).
T22 2742-2946 Sentence denotes SARS-CoV-2 is associated with an ongoing outbreak of atypical pneumonia (Covid-2019) that has affected over 90,000 people and killed more than 3,000 of those affected in >60 countries as of March 3, 2020.
T23 2947-3082 Sentence denotes On January 30, 2020, the World Health Organization declared the SARS-CoV-2 epidemic a public health emergency of international concern.
T24 3083-3260 Sentence denotes MERS-CoV was suggested to originate from bats, but the reservoir host fueling spillover to humans is unequivocally dromedary camels (Haagmans et al., 2014, Memish et al., 2013).
T25 3261-3488 Sentence denotes Both SARS-CoV and SARS-CoV-2 are closely related and originated in bats, who most likely serve as reservoir host for these two viruses (Ge et al., 2013, Hu et al., 2017, Li et al., 2005b, Yang et al., 2015a, Zhou et al., 2020).
T26 3489-3737 Sentence denotes Whereas palm civets and racoon dogs have been recognized as intermediate hosts for zoonotic transmission of SARS-CoV between bats and humans (Guan et al., 2003, Kan et al., 2005, Wang et al., 2005), the SARS-CoV-2 intermediate host remains unknown.
T27 3738-4126 Sentence denotes The recurrent spillovers of coronaviruses in humans along with detection of numerous coronaviruses in bats, including many SARS-related coronaviruses (SARSr-CoVs), suggest that future zoonotic transmission events may continue (Anthony et al., 2017, Ge et al., 2013, Hu et al., 2017, Li et al., 2005b, Menachery et al., 2015, Menachery et al., 2016, Yang et al., 2015a, Zhou et al., 2020).
T28 4127-4368 Sentence denotes In addition to the highly pathogenic zoonotic pathogens SARS-CoV, MERS-CoV, and SARS-CoV-2, all belonging to the β-coronavirus genus, four low-pathogenicity coronaviruses are endemic in humans: HCoV-OC43, HCoV-HKU1, HCoV-NL63, and HCoV-229E.
T29 4369-4461 Sentence denotes To date, no therapeutics or vaccines are approved against any human-infecting coronaviruses.
T30 4462-4639 Sentence denotes Coronavirus entry into host cells is mediated by the transmembrane spike (S) glycoprotein that forms homotrimers protruding from the viral surface (Tortorici and Veesler, 2019).
T31 4640-4799 Sentence denotes S comprises two functional subunits responsible for binding to the host cell receptor (S1 subunit) and fusion of the viral and cellular membranes (S2 subunit).
T32 4800-5130 Sentence denotes For many CoVs, S is cleaved at the boundary between the S1 and S2 subunits, which remain non-covalently bound in the prefusion conformation (Belouzard et al., 2009, Bosch et al., 2003, Burkard et al., 2014, Kirchdoerfer et al., 2016, Millet and Whittaker, 2014, Millet and Whittaker, 2015, Park et al., 2016, Walls et al., 2016a).
T33 5131-5470 Sentence denotes The distal S1 subunit comprises the receptor-binding domain(s) and contributes to stabilization of the prefusion state of the membrane-anchored S2 subunit that contains the fusion machinery (Gui et al., 2017, Kirchdoerfer et al., 2016, Pallesen et al., 2017, Song et al., 2018, Walls et al., 2016a, Walls et al., 2017b, Yuan et al., 2017).
T34 5471-5649 Sentence denotes For all CoVs, S is further cleaved by host proteases at the so-called S2′ site located immediately upstream of the fusion peptide (Madu et al., 2009, Millet and Whittaker, 2015).
T35 5650-5932 Sentence denotes This cleavage has been proposed to activate the protein for membrane fusion via extensive irreversible conformational changes (Belouzard et al., 2009, Heald-Sargent and Gallagher, 2012, Millet and Whittaker, 2014, Millet and Whittaker, 2015, Park et al., 2016, Walls et al., 2017b).
T36 5933-6136 Sentence denotes As a result, coronavirus entry into susceptible cells is a complex process that requires the concerted action of receptor-binding and proteolytic processing of the S protein to promote virus-cell fusion.
T37 6137-6293 Sentence denotes Different coronaviruses use distinct domains within the S1 subunit to recognize a variety of attachment and entry receptors, depending on the viral species.
T38 6294-6576 Sentence denotes Endemic human coronaviruses OC43 and HKU1 attach via their S domain A (SA) to 5-N-acetyl-9-O-acetyl-sialosides found on glycoproteins and glycolipids at the host cell surface to enable entry into susceptible cells (Hulswit et al., 2019, Tortorici et al., 2019, Vlasak et al., 1988).
T39 6577-6848 Sentence denotes MERS-CoV S, however, uses domain A to recognize non-acetylated sialoside attachment receptors (Li et al., 2017, Park et al., 2019), which likely promote subsequent binding of domain B (SB) to the entry receptor, dipeptidyl-peptidase 4 (Lu et al., 2013, Raj et al., 2013).
T40 6849-7119 Sentence denotes SARS-CoV and several SARS-related coronaviruses (SARSr-CoV) interact directly with angiotensin-converting enzyme 2 (ACE2) via SB to enter target cells (Ge et al., 2013, Kirchdoerfer et al., 2018, Li et al., 2005a, Li et al., 2003, Song et al., 2018, Yang et al., 2015a).
T41 7120-7327 Sentence denotes As the coronavirus S glycoprotein is surface-exposed and mediates entry into host cells, it is the main target of neutralizing antibodies (Abs) upon infection and the focus of therapeutic and vaccine design.
T42 7328-7600 Sentence denotes S trimers are extensively decorated with N-linked glycans that are important for proper folding (Rossen et al., 1998) and for modulating accessibility to host proteases and neutralizing Abs (Walls et al., 2016b, Walls et al., 2019, Xiong et al., 2018, Yang et al., 2015b).
T43 7601-7962 Sentence denotes We previously characterized potent human-neutralizing Abs from rare memory B cells of individuals infected with SARS-CoV (Traggiai et al., 2004) or MERS-CoV (Corti et al., 2015) in complex with SARS-CoV S and MERS-CoV S to provide molecular-level information of the mechanism of competitive inhibition of SB attachment to the host receptor (Walls et al., 2019).
T44 7963-8234 Sentence denotes The S230 anti-SARS-CoV Ab also acted by functionally mimicking receptor attachment and promoting S fusogenic conformational rearrangements through a ratcheting mechanism that elucidated the unique nature of the coronavirus membrane fusion activation (Walls et al., 2019).
T45 8235-8390 Sentence denotes We report here that ACE2 could mediate SARS-CoV-2 S-mediated entry into cells, establishing it as a functional receptor for this newly emerged coronavirus.
T46 8391-8579 Sentence denotes The SARS-CoV-2 SB engages human ACE2 (hACE2) with comparable affinity to SARS-CoV SB from viral isolates associated with the 2002–2003 epidemic (i.e., binding with high affinity to hACE2).
T47 8580-8708 Sentence denotes Tight binding to hACE2 could partially explain the efficient transmission of SARS-CoV-2 in humans, as was the case for SARS-CoV.
T48 8709-8919 Sentence denotes We identified the presence of an unexpected furin cleavage site at the S1/S2 boundary of SARS-CoV-2 S, which is cleaved during biosynthesis—a novel feature setting this virus apart from SARS-CoV and SARSr-CoVs.
T49 8920-9231 Sentence denotes Abrogation of this cleavage motif moderately affected SARS-CoV-2 S-mediated entry into VeroE6 or BHK cells but may contribute to expand the tropism of this virus, as reported for several highly pathogenic avian influenza viruses and pathogenic Newcastle disease virus (Klenk and Garten, 1994, Steinhauer, 1999).
T50 9232-9456 Sentence denotes We determined cryoelectron microscopy (cryo-EM) structures of the SARS-CoV-2 S ectodomain trimer and reveal that it adopts multiple SB conformations that are reminiscent of previous reports on both SARS-CoV S and MERS-CoV S.
T51 9457-9591 Sentence denotes Finally, we show that SARS-CoV S mouse polyclonal sera potently inhibited entry into target cells of SARS-CoV-2 S pseudotyped viruses.
T52 9592-9727 Sentence denotes Collectively, these results pave the way for designing vaccines eliciting broad protection against SARS-CoV-2, SARS-CoV, and SARSr-CoV.
T53 9729-9736 Sentence denotes Results
T54 9738-9778 Sentence denotes ACE2 Is an Entry Receptor for SARS-CoV-2
T55 9779-9944 Sentence denotes The SARS-CoV-2 S glycoprotein shares 76% amino acid sequence identity with the SARS-CoV S Urbani and 80% identity with bat SARSr-CoV ZXC21 S and ZC45 S glycoprotein.
T56 9945-10148 Sentence denotes The latter two SARSr-CoV sequences were identified from Rinolophus sinicus (Chinese horseshoe bats), the species from which SARSr-CoV WIV-1 and WIV-16 were isolated (Ge et al., 2013, Yang et al., 2015a).
T57 10149-10400 Sentence denotes Furthermore, Zhou et al. (2020) recently reported that SARS-CoV-2 is most closely related to the bat SARSr-CoV RaTG13, with which it forms a distinct lineage from other SARSr-CoVs, and that their S glycoproteins share 97% amino acid sequence identity.
T58 10401-10701 Sentence denotes SARS-CoV recognizes its entry receptor hACE2 at the surface of type II pneumocytes using SB, which shares ∼75% overall amino acid sequence identity with SARS-CoV-2 SB and 50% identity within their receptor-binding motifs (RBMs) (Li et al., 2005a, Li et al., 2003, Li et al., 2005c, Wan et al., 2020).
T59 10702-11008 Sentence denotes Previous studies also showed that the host proteases cathepsin L and TMPRSS2 prime SARS-CoV S for membrane fusion through cleavage at the S1/S2 and at the S2′ sites (Belouzard et al., 2009, Bosch et al., 2008, Glowacka et al., 2011, Matsuyama et al., 2010, Millet and Whittaker, 2015, Shulla et al., 2011).
T60 11009-11186 Sentence denotes We set out to investigate the functional determinants of S-mediated entry into target cells using a murine leukemia virus (MLV) pseudotyping system (Millet and Whittaker, 2016).
T61 11187-11459 Sentence denotes To assess the ability of SARS-CoV-2 S to promote entry into target cells, we first compared transduction of SARS-CoV-2 S-MLV and SARS-CoV S-MLV into VeroE6 cells, that are known to express ACE2 and support SARS-CoV replication (Drosten et al., 2003, Ksiazek et al., 2003).
T62 11460-11607 Sentence denotes Both pseudoviruses entered cells equally well (Figure 1 A), suggesting that SARS-CoV-2 S-MLV could use African green monkey ACE2 as entry receptor.
T63 11608-11796 Sentence denotes To confirm these results, we evaluated entry into BHK cells and observed that transient transfection with hACE2 rendered them susceptible to transduction with SARS-CoV-2 S-MLV (Figure 1B).
T64 11797-11978 Sentence denotes These results demonstrate hACE2 is a functional receptor for SARS-CoV-2, in agreement with recently reported findings (Hoffmann et al., 2020, Letko et al., 2020, Zhou et al., 2020).
T65 11979-12034 Sentence denotes Figure 1 ACE2 Is a Functional Receptor for SARS-CoV-2 S
T66 12035-12134 Sentence denotes (A) Entry of MLV pseudotyped with SARS-CoV-2 S, SARS-CoV S and SARS-CoV-2 Sfur/mut in VeroE6 cells.
T67 12135-12210 Sentence denotes Data are represented as mean ± standard deviation of technical triplicates.
T68 12211-12329 Sentence denotes (B) Entry of MLV pseudotyped with SARS-CoV-2 S or SARS-CoV-2 Sfur/mut in BHK cells transiently transfected with hACE2.
T69 12330-12450 Sentence denotes The experiments were carried out with two independent pseudovirus preparations and a representative experiment is shown.
T70 12451-12526 Sentence denotes Data are represented as mean ± standard deviation of technical triplicates.
T71 12527-12710 Sentence denotes (C) Sequence alignment of SARS-CoV-2 S with multiple related SARS-CoV and SARSr-CoV S glycoproteins reveals the introduction of an S1/S2 furin cleavage site in this novel coronavirus.
T72 12711-12789 Sentence denotes Identical and similar positions are respectively shown with white or red font.
T73 12790-12888 Sentence denotes The four amino acid residue insertion at SARS-CoV-2 S positions 681-684 is indicated with periods.
T74 12889-12943 Sentence denotes The entire sequence alignment is presented in Data S1.
T75 12944-13049 Sentence denotes (D) Western blot analysis of SARS-CoV S-MLV, SARS-CoV-2 S-MLV, and SARS-CoV-2 Sfur/mut-MLV pseudovirions.
T76 13050-13067 Sentence denotes See also Data S1.
T77 13068-13262 Sentence denotes Sequence analysis of SARS-CoV-2 S reveals the presence of a four amino acid residue insertion at the boundary between the S1 and S2 subunits compared with SARS-CoV S and SARSr-CoV S (Figure 1C).
T78 13263-13454 Sentence denotes This results in the introduction of a furin cleavage site, a feature conserved among the 144 SARS-CoV-2 isolates sequenced to date but not in the closely related RaTG13 S (Zhou et al., 2020).
T79 13455-13660 Sentence denotes Using western blot analysis, we observed that SARS-CoV-2 S was virtually entirely processed at the S1/S2 site during biosynthesis in HEK293T cells, presumably by furin in the Golgi compartment (Figure 1D).
T80 13661-13777 Sentence denotes This observation contrasts with SARS-CoV S, which was incorporated into pseudovirions largely uncleaved (Figure 1D).
T81 13778-14061 Sentence denotes To study the influence on pseudovirus entry of the SARS-CoV-2 S1/S2 furin cleavage site, we designed an S mutant lacking the four amino acid residue insertion and the furin cleavage site by mutating Q677TNSPRRAR↓SV687 (wild-type SARS-CoV-2 S) to Q677TILR↓SV683 (SARS-CoV-2 Sfur/mut).
T82 14062-14258 Sentence denotes SARS-CoV-2 Sfur/mut preserves only the conserved arginine residue at position 685 of wild-type SARS-CoV-2 S, thereby mimicking the S1/S2 cleavage site of the related SARSr-CoV S CZX21 (Figure 1D).
T83 14259-14591 Sentence denotes SARS-CoV-2 Sfur/mut is therefore expected to undergo processing at the S1/S2 site upon encountering a target cell, similar to SARS-CoV S and SARSr-CoV S, i.e., via TMPRSS2 and/or cathepsin L (Belouzard et al., 2009, Bosch et al., 2008, Glowacka et al., 2011, Matsuyama et al., 2010, Millet and Whittaker, 2015, Shulla et al., 2011).
T84 14592-14675 Sentence denotes As expected, SARS-CoV-2 Sfur/mut-MLV harbored uncleaved S upon budding (Figure 1D).
T85 14676-14906 Sentence denotes The observed transduction efficiency of VeroE6 cells was higher for SARS-CoV-2 Sfur/mut-MLV than for SARS-CoV-2 S-MLV (Figure 1A), whereas the opposite trend was observed for transduction of hACE2-expressing BHK cells (Figure 1B).
T86 14907-15067 Sentence denotes These results suggest that S1/S2 cleavage during S biosynthesis was not necessary for S-mediated entry in the conditions of our experiments (Figures 1C and 1D).
T87 15068-15469 Sentence denotes We speculate that the detection of a polybasic cleavage site in the fusion glycoprotein of SARS-CoV-2 could putatively expand its tropism and/or enhance its transmissibility, compared with SARS-CoV and SARSr-CoV isolates, due to the near-ubiquitous distribution of furin-like proteases and their reported effects on other viruses (Klenk and Garten, 1994, Millet and Whittaker, 2015, Steinhauer, 1999).
T88 15471-15535 Sentence denotes SARS-CoV-2 Recognizes hACE2 with Comparable Affinity to SARS-CoV
T89 15536-15780 Sentence denotes The binding affinity of SARS-CoV for hACE2 correlates with the overall rate of viral replication in distinct species as well as with transmissibility and disease severity (Guan et al., 2003, Li et al., 2004, Li et al., 2005c, Wan et al., 2020).
T90 15781-16040 Sentence denotes Indeed, specific SB mutations enabled efficient binding to hACE2 of SARS-CoV isolates from the three phases of the 2002–2003 epidemic, which were associated with marked disease severity (Consortium, 2004, Kan et al., 2005, Li et al., 2005c, Sui et al., 2004).
T91 16041-16257 Sentence denotes In contrast, SARS-CoV isolates detected during the brief 2003–2004 re-emergence interacted more weakly with hACE2 and had low pathogenicity and transmissibility (Consortium, 2004, Kan et al., 2005, Li et al., 2005c).
T92 16258-16430 Sentence denotes To understand the contribution of receptor interaction to the infectivity of SARS-CoV-2, we characterized engagement of hACE2 by SARS-CoV-2 SB and SARS-CoV SB side-by-side.
T93 16431-16609 Sentence denotes We used biolayer interferometry to study binding kinetics and affinity of the purified hACE2 ectodomain to SARS-CoV-2 SB and SARS-CoV SB immobilized at the surface of biosensors.
T94 16610-16877 Sentence denotes We found that hACE2 bound to SARS-CoV-2 SB and SARS-CoV SB with respective equilibrium dissociation constants of 1.2 nM (Figure 2 A) and 5.0 nM (Figure 2B), and comparable kinetic rate constants, although the off-rate, were slightly higher for SARS-CoV SB (Table 1 ).
T95 16878-17196 Sentence denotes The affinity determined here for SARS-CoV SB binding to hACE2 is in line with prior studies and the tighter apparent interactions formed by SARS-CoV SB compared with the SARS-CoV S1 subunit or the SARS-CoV S trimer (Kirchdoerfer et al., 2018, Li et al., 2005c, Sui et al., 2004, Walls et al., 2019, Wong et al., 2004).
T96 17197-17402 Sentence denotes Previous structural work identified 14 positions that are key for binding of SARS-CoV SB to hACE2: T402, R426, Y436, Y440, Y442, L472, N473, Y475, N479, Y484, T486, T487, G488, and Y491 (Li et al., 2005a).
T97 17403-17892 Sentence denotes Analysis of the 144 SARS-CoV-2 genome sequences available from the Global Initiative on Sharing All Influenza Data (GISAID) (Elbe and Buckland-Merrett, 2017) shows that 8 out of these 14 positions are strictly conserved in SARS-CoV-2 SB, whereas the other 6 positions are (semi)conservatively substituted: R426SARS-CoVN439SARS-CoV-2, Y442SARS-CoVL455SARS-CoV-2, L472SARS-CoVF486SARS-CoV-2, N479SARS-CoVQ493SARS-CoV-2, Y484SARS-CoVQ498SARS-CoV-2, and T487SARS-CoVN501SARS-CoV-2 (Figure 2C).
T98 17893-18027 Sentence denotes The conservation of many key contact residues could explain the similar binding affinities of SARS-CoV-2 SB and SARS-CoV SB for hACE2.
T99 18028-18146 Sentence denotes No mutations of residues predicted to contact hACE2 have been observed among SARS-CoV-2 S sequences available to date.
T100 18147-18382 Sentence denotes However, we note that SARSr-CoV ZXC21 and ZC45, which harbor the most closely related S sequences after SARSr-CoV RaTG13, have a deletion in the RBD that could affect binding to hACE2 (between SARS-CoV-2 S residues 473–486 ) (Data S1).
T101 18383-18711 Sentence denotes Collectively, these results suggest that SARS-CoV-2 is at least as well adapted to the hACE2 ortholog as the 2002–2003 epidemic strains of SARS-CoV, which could explain the efficient transduction efficiency mediated by their respective S glycoproteins (Figures 1A and 1B) and the current rapid SARS-CoV-2 transmission in humans.
T102 18712-18789 Sentence denotes Figure 2 SARS-CoV-2 S Recognizes hACE2 with Comparable Affinity to SARS-CoV S
T103 18790-18917 Sentence denotes (A and B) Biolayer interferometry binding analysis of the hACE2 ectodomain to immobilized SARS-CoV-2 SB (A) or SARS-CoV SB (B).
T104 18918-19030 Sentence denotes The experiments were repeated with different protein preparations and one representative set of curves is shown.
T105 19031-19109 Sentence denotes Dotted lines correspond to a global fit of the data using a 1:1 binding model.
T106 19110-19221 Sentence denotes (C) Sequence alignment of SARS-CoV-2 SB and SARS-CoV SB Urbani (late phase of the 2002–2003 SARS-CoV epidemic).
T107 19222-19300 Sentence denotes Identical and similar positions are respectively shown with white or red font.
T108 19301-19439 Sentence denotes The single amino acid insertion at position 483 of the SARS-CoV-2 SB is indicated with a period at the corresponding SARS-CoV SB position.
T109 19440-19529 Sentence denotes The 14 residues that are key for binding of SARS-CoV SB to hACE2 are labeled with a star.
T110 19530-19547 Sentence denotes See also Data S1.
T111 19548-19649 Sentence denotes Table 1 Kinetic Analysis of hACE2 Binding to SARS-CoV-2 SB and SARS-CoV SB by Biolayer Interferometry
T112 19650-19675 Sentence denotes SARS-CoV-2 SB SARS-CoV SB
T113 19676-19703 Sentence denotes KD (nM) 1.2 ± 0.1 5.0 ± 0.1
T114 19704-19773 Sentence denotes kon (M−1.s−1) 1.4 × 105 (2.3 ± 1.4 × 105) 1.4 × 105 (1.7 ± 0.7 × 105)
T115 19774-19843 Sentence denotes koff (s−1) 1.6 × 10−4 (1.7 ± 0.8 × 10−4) 7.1x 10−4 (8.7 ± 5.1 × 10−4)
T116 19844-20076 Sentence denotes Values reported represent the global fit to the data shown in Figures 2A and 2B and the averages obtained from five (SARS-CoV-2) or four (SARS-CoV) replicates carried out with different protein preparations are shown in parentheses.
T117 20078-20130 Sentence denotes Architecture of the SARS-CoV-2 S Glycoprotein Trimer
T118 20131-20570 Sentence denotes To enable single-particle cryo-EM study of the SARS-CoV-2 S glycoprotein, we designed a prefusion stabilized ectodomain trimer construct with an abrogated furin S1/S2 cleavage site (Tortorici et al., 2019, Walls et al., 2017a, Walls et al., 2016a, Walls et al., 2019), two consecutive proline stabilizing mutations (Kirchdoerfer et al., 2018, Pallesen et al., 2017), and a C-terminal foldon trimerization domain (Miroshnikov et al., 1998).
T119 20571-20777 Sentence denotes Three-dimensional (3D) classification of the cryo-EM data revealed the presence of multiple conformational states of SARS-CoV-2 S corresponding to distinct organization of the SB domains within the S1 apex.
T120 20778-20983 Sentence denotes Approximately half of the particle images selected correspond to trimers harboring a single SB domain opened whereas the remaining half was accounted for by closed trimers with the three SB domains closed.
T121 20984-21128 Sentence denotes A recently determined SARS-CoV-2 S structure also detected trimers with a single SB domain opened but none entirely closed (Wrapp et al., 2020).
T122 21129-21539 Sentence denotes The observed conformational variability of SB domains is reminiscent of observations made with SARS-CoV S and MERS-CoV S trimers, although we did not detect trimers with two SB domains open and the distribution of particles across the S conformational landscape varies among studies (Gui et al., 2017, Kirchdoerfer et al., 2018, Pallesen et al., 2017, Song et al., 2018, Walls et al., 2019, Yuan et al., 2017).
T123 21540-21796 Sentence denotes We determined a reconstruction of the closed SARS-CoV-2 S ectodomain trimer at 2.8 Å resolution (applying 3-fold symmetry) and an asymmetric reconstruction of the trimer with a single SB domain opened at 3.2 Å resolution (Figures 3 A–3H and S1 ; Table S1).
T124 21797-21964 Sentence denotes The S2 fusion machinery is the best resolved part of the map, whereas the SA and SB domains are less well resolved, presumably because of conformational heterogeneity.
T125 21965-22251 Sentence denotes The atomic model comprises residues 27-1147, with internal breaks corresponding to flexible regions (including part of the RBM), and lacks the C-terminal most segment (including the heptad repeat 2) that is not visible in the map, as is the case for all S structures determined to date.
T126 22252-22520 Sentence denotes Overall, the SARS-CoV-2 S ectodomain is a 160-Å-long trimer with a triangular cross-section, resembling the closely related SARS-CoV S structure (Figures S2 A–S2F) (Gui et al., 2017, Kirchdoerfer et al., 2018, Song et al., 2018, Walls et al., 2019, Yuan et al., 2017).
T127 22521-22581 Sentence denotes Figure 3 Cryo-EM Structures of the SARS-CoV-2 S Glycoprotein
T128 22582-22637 Sentence denotes (A) Closed SARS-CoV-2 S trimer unsharpened cryo-EM map.
T129 22638-22753 Sentence denotes (B and C) Two orthogonal views from the side (B) and top (C) of the atomic model of the closed SARS-CoV-2 S trimer.
T130 22754-22841 Sentence denotes (D) Partially open SARS-CoV-2 S trimer unsharpened cryo-EM map (one SB domain is open).
T131 22842-22953 Sentence denotes (E-F) Two orthogonal views from the side (E) and top (F) of the atomic model of the closed SARS-CoV-2 S trimer.
T132 22954-22991 Sentence denotes The glycans were omitted for clarity.
T133 22992-23019 Sentence denotes See also Figures S1 and S2.
T134 23020-23100 Sentence denotes Figure S1 Cryo-EM Data Processing and Validation, Related to Figures 3, 4, and 5
T135 23101-23105 Sentence denotes A-B.
T136 23106-23209 Sentence denotes Representative electron micrograph (A) and class averages (B) of SARS-CoV-2 S embedded in vitreous ice.
T137 23210-23220 Sentence denotes Scale bar:
T138 23221-23227 Sentence denotes 100nm.
T139 23228-23230 Sentence denotes C.
T140 23231-23333 Sentence denotes Gold-standard Fourier shell correlation curves for the closed (blue) and partially open trimers (red).
T141 23334-23391 Sentence denotes The 0.143 cutoff is indicated by horizontal dashed lines.
T142 23392-23396 Sentence denotes D-E.
T143 23397-23503 Sentence denotes Local resolution map calculated using cryoSPARC for the closed (D) and partially open (E) reconstructions.
T144 23504-23600 Sentence denotes Figure S2 Comparison of the SARS-CoV-2 and SARS-CoV S Structures, Related to Figures 3, 4, and 5
T145 23601-23699 Sentence denotes Ribbon diagrams of the SARS-CoV-2 S (A) and SARS-CoV S (PDB 6NB6, D) ectodomain cryoEM structures.
T146 23700-23748 Sentence denotes The SARS-CoV-2 (B) and SARS-CoV (E) S1 subunits.
T147 23749-23797 Sentence denotes The SARS-CoV-2 (C) and SARS-CoV (F) S2 subunits.
T148 23798-24149 Sentence denotes As is the case for other β-coronavirus S glycoproteins, including SARS-CoV S (Gui et al., 2017, Kirchdoerfer et al., 2018, Pallesen et al., 2017, Park et al., 2019, Song et al., 2018, Tortorici et al., 2019, Walls et al., 2016a, Walls et al., 2016b, Walls et al., 2019, Yuan et al., 2017), the S1 subunit has a V-shaped architecture (Figures S2B–S2E).
T149 24150-24372 Sentence denotes In the closed S trimer, the three hACE2-recognition motifs, whose location was inferred based on the crystal structure of SARS-CoV SB in complex with hACE2 (Li et al., 2005a), are buried at the interface between protomers.
T150 24373-24772 Sentence denotes As a result, SARS-CoV-2 SB opening is expected to be necessary for interacting with ACE2 at the host cell surface and initiating the conformational changes leading to cleavage of the S2′ site, membrane fusion and viral entry (Gui et al., 2017, Kirchdoerfer et al., 2018, Millet and Whittaker, 2014, Pallesen et al., 2017, Park et al., 2016, Song et al., 2018, Walls et al., 2019, Yuan et al., 2017).
T151 24773-24998 Sentence denotes As the SARS-CoV-2 and SARS-CoV S2 subunits share 88% sequence identity, they are structurally conserved and can be superimposed with 1.2 Å root-mean-square deviation (rmsd) over 417 aligned Cα positions (Figures S2E and S2F).
T152 24999-25139 Sentence denotes Only the most N-terminal part of the fusion peptide is resolved in the map, as was the case for previously determined SARS-CoV S structures.
T153 25140-25402 Sentence denotes The sequence and conformational conservation of the fusion peptide region observed across SARS-CoV-2 S and SARS-CoV S suggests that Abs targeting this functionally important motif might cross-react and neutralize the two viruses as well as related coronaviruses.
T154 25403-25610 Sentence denotes We previously showed that coronavirus S glycoproteins are densely decorated by heterogeneous N-linked glycans protruding from the trimer surface (Walls et al., 2016b, Walls et al., 2019, Xiong et al., 2018).
T155 25611-25821 Sentence denotes These oligosaccharides participate in S folding (Rossen et al., 1998), affect priming by host proteases (Yang et al., 2015b), and might modulate antibody recognition (Pallesen et al., 2017, Walls et al., 2019).
T156 25822-25978 Sentence denotes SARS-CoV-2 S comprise 22 N-linked glycosylation sequons per protomer and oligosaccharides are resolved in the cryo-EM map for 16 of these sites (Figure 4 ).
T157 25979-26169 Sentence denotes By comparison, SARS-CoV S possesses 23 N-linked glycosylation sequons per protomer, and we previously experimentally confirmed that at least 19 of them are glycosylated (Walls et al., 2019).
T158 26170-26266 Sentence denotes 20 out of 22 SARS-CoV-2 S N-linked glycosylation sequons are conserved in SARS-CoV S (Table 2 ).
T159 26267-26403 Sentence denotes Specifically, 9 out of 13 glycans in the S1 subunit and all 9 glycans in the S2 subunit are conserved among SARS-CoV-2 S and SARS-CoV S.
T160 26404-26628 Sentence denotes Furthermore, S2 N-linked glycosylation sequons are mostly conserved across SARSr-CoV S glycoproteins, suggesting that accessibility of the fusion machinery to Abs will be comparable among these viruses (Table 2 and Data S1).
T161 26629-26687 Sentence denotes Figure 4 Organization of the SARS-CoV-2 S N-Linked Glycans
T162 26688-26840 Sentence denotes (A–C) Ribbon diagrams of the SARS-CoV-2 S closed structure rendered as a surface with glycans resolved in the cryo-EM map rendered as dark blue spheres.
T163 26841-26870 Sentence denotes See also Table 2 and Data S1.
T164 26871-26956 Sentence denotes Table 2 Conservation of N-Linked Glycosylation Sequons in SARS-CoV-2 S and SARS-CoV S
T165 26957-26980 Sentence denotes SARS-CoV-2 S SARS-CoV S
T166 26981-26992 Sentence denotes N17LT T21FD
T167 26993-27004 Sentence denotes P25PA N29YT
T168 27005-27016 Sentence denotes N61VT N65VT
T169 27017-27028 Sentence denotes H69VS N73HT
T170 27029-27040 Sentence denotes N74GT . . .
T171 27041-27054 Sentence denotes S112KT N109KS
T172 27055-27068 Sentence denotes N121NA N118NS
T173 27069-27082 Sentence denotes N122AT N119ST
T174 27083-27096 Sentence denotes N149KS T146QT
T175 27097-27110 Sentence denotes N165CT N158CT
T176 27111-27124 Sentence denotes N234IT N227IT
T177 27125-27138 Sentence denotes N282GT N269GT
T178 27139-27152 Sentence denotes N331IT N318IT
T179 27153-27166 Sentence denotes N343AT N330AT
T180 27167-27180 Sentence denotes N370SA N357ST
T181 27181-27194 Sentence denotes N603TS N589AS
T182 27195-27208 Sentence denotes N616CT N602CT
T183 27209-27222 Sentence denotes N657NS D643TS
T184 27223-27236 Sentence denotes N709NS N691NT
T185 27237-27250 Sentence denotes N717FT N699FS
T186 27251-27264 Sentence denotes N801FS N783FS
T187 27265-27280 Sentence denotes N1074FT N1056FT
T188 27281-27296 Sentence denotes N1098GT N1080GT
T189 27297-27312 Sentence denotes N1134NT N1116NT
T190 27313-27328 Sentence denotes N1158HT N1140HT
T191 27329-27344 Sentence denotes N1173AS N1155AS
T192 27345-27360 Sentence denotes N1194ES N1176ES
T193 27361-27462 Sentence denotes Italic font indicates the absence of a glycosylation sequon and deletions are indicated with periods.
T194 27463-27527 Sentence denotes Glycans observed in the SARS-CoV-2 S cryo-EM map are underlined.
T195 27528-27545 Sentence denotes See also Data S1.
T196 27547-27603 Sentence denotes SARS-CoV S Elicits Neutralizing Abs Against SARS-CoV-2 S
T197 27604-27850 Sentence denotes Mapping of the sequence conservation across multiple S sequences from the sarbecovirus subgenus underscores that the S2 fusion machinery is more conserved than the S1 subunit with the highest divergence found within SA and SB (Figures 5A and 5B).
T198 27851-28206 Sentence denotes These observations are in line with (1) the fact that some, but not all, of these viruses use ACE2 as entry receptor (Ge et al., 2013, Ren et al., 2008, Yang et al., 2015a); and (2) that the S1 subunit is more exposed at the viral surface than the fusion machinery and is likely to be subject to a more stringent selection pressure from the immune system.
T199 28207-28302 Sentence denotes Figure 5 SARS-CoV S Elicits Antibodies Neutralizing SARS-CoV-2 S-Mediated Entry into Host Cells
T200 28303-28442 Sentence denotes (A and B) Sequence conservation of sarbecovirus S glycoproteins plotted on the SARS-CoV-2 S structure viewed from the side (A) and top (B).
T201 28443-28580 Sentence denotes The sequence alignment was generated using 48 SARS-CoV-2 S sequences obtained from GISAID in addition to the sequences listed in Data S1.
T202 28581-28702 Sentence denotes (C) Entry of SARS-CoV-2 S-MLV and SARS-CoV S-MLV is potently inhibited by four SARS-CoV S mouse polyclonal immune plasma.
T203 28703-28873 Sentence denotes Based on these observations, we hypothesized that exposure to one of the two viruses could elicit cross-reactive and potentially neutralizing Abs against the other virus.
T204 28874-29049 Sentence denotes We therefore investigated the ability of plasma from four mice immunized with a stabilized SARS-CoV S to inhibit SARS-CoV-2 S- and SARS-CoV S-mediated entry into target cells.
T205 29050-29207 Sentence denotes All sera tested completely inhibited transduction of SARS-CoV S-MLV and reduced SARS-CoV-2 S-MLV transduction to ∼10% of control in VeroE6 cells (Figure 5C).
T206 29208-29565 Sentence denotes The elicitation of a heterotypic response blocking SARS-CoV-2 S-mediated entry into host cells concurs with the sequence and structural conservation of SARS-CoV-2 S and SARS-CoV S along with their comparable glycans shields and suggests that immunity against one virus of the sarbecovirus subgenus can potentially provide protection against related viruses.
T207 29567-29577 Sentence denotes Discussion
T208 29578-29693 Sentence denotes Receptor recognition is the first step of viral infection and is a key determinant of host cell and tissue tropism.
T209 29694-29863 Sentence denotes Enhanced binding affinity between SARS-CoV S and hACE2 was proposed to correlate with increased virus transmissibility and disease severity in humans (Li et al., 2005c).
T210 29864-30199 Sentence denotes Indeed, SARS-CoV isolates from the three phases of the 2002–2003 epidemic were more efficiently transmitted among humans and more pathogenic than the isolates associated with the 2003–2004 re-emergence that caused only a few cases, in line with their binding affinities for hACE2 (Consortium, 2004, Kan et al., 2005, Li et al., 2005c).
T211 30200-30417 Sentence denotes Moreover, the ability to engage ACE2 from different animal species appears to reflect host susceptibility to SARS-CoV infection and facilitated the jump of the virus from animals to humans (Li, 2008, Li et al., 2004).
T212 30418-30705 Sentence denotes We report here that SARS-CoV-2 uses hACE2 as an entry receptor and recognizes it with a similar affinity to the 2002–2003 SARS-CoV isolates, which suggests it can spread efficiently in humans, in agreement with the numerous SARS-CoV-2 human-to-human transmission events reported to date.
T213 30706-30934 Sentence denotes Besides binding to host cell receptors, priming of the S glycoprotein by host proteases through cleavage at the S1/S2 and the S2′ sites is another crucial factor modulating tropism and pathogenicity (Millet and Whittaker, 2015).
T214 30935-31230 Sentence denotes For instance, entry of the MERS-CoV-related bat coronavirus HKU4 into human cells required addition of exogenous trypsin, indicating that S proteolytic activation of this bat virus did not occur in human cells (despite its ability to recognize human DPP4) (Wang et al., 2014, Yang et al., 2014).
T215 31231-31443 Sentence denotes Subsequent work suggested that a glycan present near the S1/S2 boundary accounted for the lack of proteolytic priming of HKU4 S and that its removal enhanced pseudovirus entry in human cells (Yang et al., 2015b).
T216 31444-31684 Sentence denotes The presence of a polybasic cleavage site, that can be processed by furin-like proteases, is a signature of several highly pathogenic avian influenza viruses and pathogenic Newcastle disease virus (Klenk and Garten, 1994, Steinhauer, 1999).
T217 31685-31802 Sentence denotes Strikingly, SARS-CoV-2 S harbors a furin cleavage site at the S1/S2 boundary, which is processed during biosynthesis.
T218 31803-32124 Sentence denotes The presence of a furin cleavage site sets SARS-CoV-2 S apart from SARS-CoV S (and SARSr-CoV S) that possesses a monobasic S1/S2 cleavage site processed upon entry of target cells (Belouzard et al., 2009, Bosch et al., 2008, Glowacka et al., 2011, Matsuyama et al., 2010, Millet and Whittaker, 2015, Shulla et al., 2011).
T219 32125-32366 Sentence denotes We speculate that the almost ubiquitous expression of furin-like proteases could participate in expanding SARS-CoV-2 cell and tissue tropism, relative to SARS-CoV, as well as increasing its transmissibility and/or altering its pathogenicity.
T220 32367-32582 Sentence denotes We previously suggested that coronaviruses use conformational masking and glycan shielding to limit recognition by the immune response of infected hosts (Walls et al., 2016b, Walls et al., 2019, Xiong et al., 2018).
T221 32583-32884 Sentence denotes Similarly to SARS-CoV S and MERS-CoV S (Gui et al., 2017, Kirchdoerfer et al., 2018, Pallesen et al., 2017, Song et al., 2018, Walls et al., 2019, Yuan et al., 2017), we found that the SARS-CoV-2 S trimer exists in multiple, distinct conformational states resulting from SB opening at the trimer apex.
T222 32885-33091 Sentence denotes These structural changes are necessary for receptor engagement of these three viruses and lead to initiation of fusogenic conformational changes (Song et al., 2018, Walls et al., 2017b, Walls et al., 2019).
T223 33092-33336 Sentence denotes In contrast, only closed S trimers have been detected for the four other human-infecting coronaviruses: HCoV-NL63 (Walls et al., 2016b), HCoV-OC43 (Tortorici et al., 2019), HCoV-HKU1 (Kirchdoerfer et al., 2016), and HCoV-229E (Li et al., 2019).
T224 33337-33637 Sentence denotes As HCoV-NL63 and HCoV-229E are known to engage protein receptors through SB (Wong et al., 2017, Wu et al., 2009), trimer opening is also expected to occur to expose their RBMs that are otherwise buried at the interface between protomers in the closed S trimers (Li et al., 2019, Walls et al., 2016b).
T225 33638-33935 Sentence denotes Regardless of the nature of the receptor and the location of the receptor-binding domains, removal of the trimeric S1 crown is expected to be necessary for all coronaviruses to allow the large-scale S2 conformational changes leading to fusion of the viral and host membranes (Walls et al., 2017b).
T226 33936-34176 Sentence denotes Collectively, these data underscore that S glycoprotein trimers found in highly pathogenic human coronaviruses appear to exist in partially opened states, while they remain largely closed in human coronaviruses associated with common colds.
T227 34177-34631 Sentence denotes Based on the aforementioned data correlating the binding affinity of SARS-CoV for hACE2 with the rate of transmissibility, viral replication in distinct species, and disease severity (Guan et al., 2003, Li et al., 2004, Li et al., 2005c, Wan et al., 2020), we hypothesize that the most pathogenic coronaviruses will exhibit S glycoprotein trimers spontaneously sampling closed and open conformations, as is the case for SARS-CoV-2, SARS-CoV and MERS-CoV.
T228 34632-34847 Sentence denotes The striking structural similarity and sequence conservation among the SARS-CoV-2 S and SARS-CoV S glycoproteins emphasize the close relationship between these two viruses that recognize hACE2 to enter target cells.
T229 34848-35015 Sentence denotes This resemblance is further strengthened by our finding that SARS-CoV S elicited polyclonal Ab responses, potently neutralizing SARS-CoV-2 S-mediated entry into cells.
T230 35016-35400 Sentence denotes We surmise most of these Abs target the highly conserved S2 subunit (including the fusion peptide region) based on its structural similarity across SARS-CoV-2 and SARS-CoV, the lack of cross-reactivity of several SB-directed Abs (Tian et al., 2020, Wrapp et al., 2020), and previous reports showing that sera from SARS-CoV-infected individuals target this region (Zhang et al., 2004).
T231 35401-35662 Sentence denotes We note that most SARS-CoV neutralizing Abs isolated to date target the SB domain and that several of them recognize the RBM and prevent receptor engagement (Hwang et al., 2006, Rockx et al., 2008, Rockx et al., 2010, Traggiai et al., 2004, Walls et al., 2019).
T232 35663-35853 Sentence denotes As the SARS-CoV-2 and SARS-CoV SB domains share 75% amino acid sequence identity, future work will be necessary to evaluate whether any of these Abs neutralize the newly emerged coronavirus.
T233 35854-36070 Sentence denotes These findings also indicate that it might be difficult to distinguish exposure to SARS-CoV-2 from other SARSr-CoVs in serological studies using S ectodomain trimers and that specific assays will need to be designed.
T234 36071-36232 Sentence denotes Our results provide a structural framework to identify conserved and accessible epitopes across S glycoproteins that will support ongoing vaccine design efforts.
T235 36233-36456 Sentence denotes Finally, elicitation of diverse, polyclonal Ab responses might prove key in light of the diversity of viruses circulating in animal reservoirs and in preventing the possible emergence of viral neutralization escape mutants.
T236 36458-36470 Sentence denotes STAR★Methods
T237 36472-36491 Sentence denotes Key Resources Table
T238 36492-36529 Sentence denotes REAGENT or RESOURCE SOURCE IDENTIFIER
T239 36530-36540 Sentence denotes Antibodies
T240 36541-36638 Sentence denotes AlexaFluor680-conjugated AffiniPure Goat Anti Human IgG JacksonImmuno Cat# 109-625-098Lot# 139337
T241 36639-36657 Sentence denotes Biological Samples
T242 36658-36701 Sentence denotes 57BL/6J Mice Jackson Laboratory Cat# 000664
T243 36702-36747 Sentence denotes Chemicals, Peptides, and Recombinant Proteins
T244 36748-36795 Sentence denotes Thrombin EMD Millipore Ref# 605195 Lot# 2946006
T245 36796-36824 Sentence denotes One-GloEX Promega Cat# E8110
T246 36825-36881 Sentence denotes 293-Free Transfection Reagent Millipore Sigma Cat# 72181
T247 36882-36948 Sentence denotes Lipofectamine-2000 Transfection Reagent ThermoFisher Cat# 11668500
T248 36949-36982 Sentence denotes Adjuvant Sigma-Aldrich Cat# S6322
T249 36983-36997 Sentence denotes Deposited Data
T250 36998-37038 Sentence denotes SARS-CoV-2 S CryoEM maps This Paper EMD:
T251 37039-37050 Sentence denotes 21452, EMD:
T252 37051-37056 Sentence denotes 21457
T253 37057-37099 Sentence denotes SARS-CoV-2 S atomic models This Paper PDB:
T254 37100-37110 Sentence denotes 6VXX, PDB:
T255 37111-37115 Sentence denotes 6VYB
T256 37116-37136 Sentence denotes Experimental Models:
T257 37137-37147 Sentence denotes Cell Lines
T258 37148-37189 Sentence denotes Freestyle HEK293 ThermoFisher Cat# R79007
T259 37190-37251 Sentence denotes HEK293T/17 adherent Millet and Whittaker, 2016 ATCC CRL-11268
T260 37252-37313 Sentence denotes Vero(C1008)E6 adherent ECACC General Collection Cat# 85020206
T261 37314-37369 Sentence denotes Baby Hamster Kidney (BHK) ATCC Cat# CCL-10Lot# 70009857
T262 37370-37385 Sentence denotes Recombinant DNA
T263 37386-37444 Sentence denotes pCMV-SARS-CoV-2 S 2P furin cleavage mutation Genscript N/A
T264 37445-37477 Sentence denotes pcD5 - ACE2 Raj et al., 2013 N/A
T265 37478-37515 Sentence denotes pcDNA3.1- SARS-CoV-2 SB Genscript N/A
T266 37516-37552 Sentence denotes pcDNA3.1- SARS-CoV SB This paper N/A
T267 37553-37614 Sentence denotes pcDNA3.1(-) –Full-length wild-type SARS-CoV-2 S Genscript N/A
T268 37615-37691 Sentence denotes pcDNA3.1(-) –Full-length wild-type SARS-CoV S Millet and Whittaker, 2016 N/A
T269 37692-37757 Sentence denotes pCMV-murine leukemia virus gag-pol Millet and Whittaker, 2016 N/A
T270 37758-37803 Sentence denotes pTG-Luciferase Millet and Whittaker, 2016 N/A
T271 37804-37827 Sentence denotes Software and Algorithms
T272 37828-37896 Sentence denotes UCSF Chimera Goddard et al., 2007 https://www.rbvi.ucsf.edu/chimera/
T273 37897-37967 Sentence denotes UCSF ChimeraX Goddard et al., 2018 https://www.rbvi.ucsf.edu/chimerax/
T274 37968-38046 Sentence denotes Coot Emsley et al., 2010 https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/
T275 38047-38169 Sentence denotes Relion Scheres and Chen, 2012, Zivanov et al., 2019 https://www2.mrc-lmb.cam.ac.uk/relion/index.php?title=Main_Page
T276 38170-38255 Sentence denotes Rosetta Frenz et al., 2019, Wang et al., 2016 https://www.rosettacommons.org/software
T277 38256-38352 Sentence denotes Leginon Suloway et al., 2005 http://emg.nysbc.org/redmine/projects/leginon/wiki/Leginon_Homepage
T278 38353-38416 Sentence denotes WARP Tegunov and Cramer, 2019 https://github.com/cramerlab/warp
T279 38417-38469 Sentence denotes CryoSPARC Punjani et al., 2017 https://cryosparc.com
T280 38470-38534 Sentence denotes MolProbity Chen et al., 2010 http://molprobity.biochem.duke.edu/
T281 38535-38540 Sentence denotes Other
T282 38541-38652 Sentence denotes Octet Red ForteBio, Pall LLC https://www.fortebio.com/products/label-free-bli-detection/8-channel-octet-systems
T283 38653-38721 Sentence denotes Anti-Penta-HIS (HIS1K) ForteBio, Pall LLC Part# 18-5120Lot# 1910224A
T284 38722-38782 Sentence denotes HisTALON Superflow cartridge Takara Cat# 635683Lot# 1509573A
T285 38783-38835 Sentence denotes HiTrap Protein A HP GE Life Sciences Cat# 29-0485-76
T286 38836-38908 Sentence denotes Superose 6 Increase 10/300 GE Life Sciences Cat# 29-0915-96Lot# 10226998
T287 38909-38983 Sentence denotes Lacey Formvar/Carbon 400 mesh, Cu Grids Ted Pella Prod# 01885-FLot# 020218
T288 38985-39024 Sentence denotes Lead Contact and Materials Availability
T289 39025-39181 Sentence denotes Further information and requests for resources and reagents should be directed to and will be fulfilled by the Lead Contact David Veesler (dveesler@uw.edu).
T290 39182-39315 Sentence denotes The unique/stable reagents generated in this study are available from the Lead Contact with a completed Materials Transfer Agreement.
T291 39316-39414 Sentence denotes The number of replicates carried out for each experiment is described in the figure/table legends.
T292 39416-39454 Sentence denotes Experimental Model and Subject Details
T293 39456-39466 Sentence denotes Cell lines
T294 39467-39586 Sentence denotes HEK293F is a female human embryonic kidney cell line transformed and adapted to grow in suspension (Life Technologies).
T295 39587-39708 Sentence denotes HEK293F cells were grown in 293FreeStyle expression medium (Life Technologies), cultured at 37°C with 8% CO2 and 130 rpm.
T296 39709-39772 Sentence denotes HEK293T/17 is a female human embryonic kidney cell line (ATCC).
T297 39773-39841 Sentence denotes VeroE6 is a female kidney epithelial cell from African green monkey.
T298 39842-39887 Sentence denotes BHK is a kidney cell line from baby hamsters.
T299 39888-40000 Sentence denotes All adherent cells were cultured at 37°C with 8% CO2 in flasks with DMEM + 10% FBS + 1% penicillin-streptomycin.
T300 40001-40076 Sentence denotes Cells lines were not tested for mycoplasma contamination nor authenticated.
T301 40078-40092 Sentence denotes Method Details
T302 40094-40144 Sentence denotes Transient expression of SARS-CoV-2 and SARS-CoV SB
T303 40145-40407 Sentence denotes The SARS-CoV SB construct was cloned from a SARS-CoV S ectodomain (Walls et al., 2019) synthesized by GeneArt (ThermoFisher Scientific) into a modified pOPING vector with an N-terminal mu-phosphatase signal peptide and a C-terminal hexa-histidine tag (G-HHHHHH).
T304 40408-40496 Sentence denotes The boundaries of the construct are N-terminal 306RVVPSG311 and C-terminal 571LDISP5975.
T305 40497-40665 Sentence denotes The SARS-CoV-2 SB construct was synthesized by GenScript into pcDNA3.1- with an N-terminal mu-phosphatase signal peptide and a C-terminal hexa-histidine tag (G-HHHHHH).
T306 40666-40750 Sentence denotes The boundaries of the construct are N-terminal 328RFPN331 and C-terminal 530STNL533.
T307 40751-40943 Sentence denotes Both constructs were produced in 500mL HEK293F cells grown in suspension using FreeStyle 293 expression medium (Life technologies) at 37°C in a humidified 8% CO2 incubator rotating at 130 rpm.
T308 40944-41106 Sentence denotes The cultures were transfected using 293-Free transfection reagent (Millipore) with cells grown to a density of 1 million cells per mL and cultivated for 3–4 days.
T309 41107-41205 Sentence denotes The supernatants were harvested and cells resuspended for another 3–4 days, yielding two harvests.
T310 41206-41407 Sentence denotes Proteins were purified from clarified supernatants using a 5mL Cobalt affinity column (Takara), concentrated and flash frozen in a buffer containing 20 mM Tris pH 8.0 and 300 mM NaCl prior to analysis.
T311 41408-41441 Sentence denotes SDS-PAGE was run to check purity.
T312 41443-41472 Sentence denotes Transient expression of hACE2
T313 41473-41737 Sentence denotes Expression and purification of human angiotensin-converting enzyme ectodomain (ACE2, residues 1–614) fused to the Fc region of human IgG (hFc) was performed as previously described (Walls et al., 2019) and cleavage of the Fc fragment was carried out with thrombin.
T314 41738-41928 Sentence denotes Briefly, hACE2 was produced in 500mL HEK293F cells grown in suspension using FreeStyle 293 expression medium (Life technologies) at 37°C in a humidified 8% CO2 incubator rotating at 130 rpm.
T315 41929-42089 Sentence denotes The cultures were transfected using 293-Free transfection reagent (Millipore) with cells grown to a density of 1 million cells per mL and cultivated for 4 days.
T316 42090-42189 Sentence denotes The supernatants were harvested and cells resuspended for another four days, yielding two harvests.
T317 42190-42529 Sentence denotes Clarified supernatants were concentrated using Vivaflow tangential filtration cassettes (Sartorius, 10-kDa cut-off) before affinity purification using a Protein A column (GE LifeSciences) followed by gel filtration chromatography using a Superdex 200 10/300 GL column (GE Life Sciences) equilibrated in 20 mM Tris-HCl, pH 8.0, 100 mM NaCl.
T318 42530-42853 Sentence denotes The Fc tag was removed by thrombin cleavage in a reaction mixture containing 3 mg of recombinant ACE2-FC ectodomain and 10 μg of thrombin in 20 mMTris-HCl pH8.0, 150 mM NaCl and 2.5 mM CaCl2.The reaction mixture was incubated at 25°C overnight and re-loaded in a Protein A column to remove uncleaved protein and the Fc tag.
T319 42854-43040 Sentence denotes The cleaved protein was further purified by gel filtration using a Superdex 200 column 10/300 GL (GE Life Sciences) equilibrated in a buffer containing 20 mM Tris pH 8.0 and 100 mM NaCl.
T320 43041-43146 Sentence denotes The purified protein was quantified using absorption at 280 nm and concentrated to approximately 1 mg/mL·
T321 43148-43170 Sentence denotes Pseudovirus production
T322 43171-43310 Sentence denotes MLV-based SARS-CoV S, SARS-CoV-2 S, and SARS-CoV-2 Sfur/mut pseudotypes were prepared as previously described (Millet and Whittaker, 2016).
T323 43311-43558 Sentence denotes HEK293T cells were co-transfected using Lipofectamine 2000 (Life Technologies) with an S encoding-plasmid, an MLV Gag-Pol packaging construct and the MLV transfer vector encoding a luciferase reporter, according to the manufacturer’s instructions.
T324 43559-43621 Sentence denotes Cells were incubated for 5 h at 37°C with transfection medium.
T325 43622-43717 Sentence denotes Cells were then washed with DMEM two times and then DMEM containing 10% FBS was added for 60 h.
T326 43718-43879 Sentence denotes The supernatants were then harvested and filtered through 0.45-mm membranes, concentrated with a 30kDa membrane for 10 min at 3,000 rpm and then frozen at −80°C.
T327 43881-43897 Sentence denotes Western Blotting
T328 43898-44046 Sentence denotes SARS-CoV S, SARS-CoV-2 S, and SARS-CoV-2 Sfur/mut pseudovirions were thawed and 4X SDS loading buffer was added prior to boiling for 10 min at 95°C.
T329 44047-44146 Sentence denotes Samples were run on a 4%–20% gradient Tris-Glycine Gel (BioRad) and transferred to a PVDF membrane.
T330 44147-44389 Sentence denotes An anti-S2 SARS-CoV S monoclonal primary antibody (1:150 dilution) and an Alexa Fluor 680-conjugated goat anti-human or mouse secondary antibody (1:30,000 and 1:15,000 dilution respectively, Jackson Laboratory) were used for Western-blotting.
T331 44390-44436 Sentence denotes A LI-COR processor was used to develop images.
T332 44438-44462 Sentence denotes Pseudovirus entry assays
T333 44463-44527 Sentence denotes VeroE6 and BHK cells were cultured in 10% FBS, 1% PenStrep DMEM.
T334 44528-44615 Sentence denotes BHK or VeroE6 cells were plated into 12 well plates at a density of 0.3 × 106 for 16 h.
T335 44616-44789 Sentence denotes BHK cells were either not transfected or transfected with 0.8 μg ACE2 per well using standard lipofectamine2000 (Life Technologies) protocols and incubated for another 16 h.
T336 44790-44882 Sentence denotes 20uL of concentrated pseudovirus was added to the wells after washing three times with DMEM.
T337 44883-44968 Sentence denotes After 2-3 h, 20% FBS and 2% PenStrep containing DMEM was added to the cells for 48 h.
T338 44969-45175 Sentence denotes Following the 48-h infection, One-Glo-EX (Promega) was added to the cells in equivalent culturing volume and incubated in the dark for 10 min prior to reading on a Varioskan LUX plate reader (ThermoFisher).
T339 45176-45384 Sentence denotes For entry inhibition assays, 1:100 diluted plasma was incubated with an equal amount of pseudovirus for 30 min at room temperature prior to infection with normalized amounts of pseudovirus added to the cells.
T340 45385-45471 Sentence denotes Measurements were done in triplicate and relative luciferase units (RLU) were plotted.
T341 45473-45496 Sentence denotes Biolayer interferometry
T342 45497-45591 Sentence denotes Assays were performed on an Octet Red (ForteBio) instrument at 30°C with shaking at 1,000 RPM.
T343 45592-45715 Sentence denotes Anti-penta His biosensors were hydrated in water for 30 min prior to a 1 min incubation in 10X kinetics buffer (undiluted).
T344 45716-45881 Sentence denotes Either SARS-CoV-2 SB or SARS-CoV SB were loaded at 10-20 μg/mL in 10X Kinetics Buffer for 200-900 s prior to baseline equilibration for 180 s in 10X kinetics buffer.
T345 45882-46062 Sentence denotes Association of ACE2 in 10X kinetics buffer at various concentrations in a two-fold dilution series from 20nM to 2.5nM was carried out for 1,000 s prior to dissociation for 1,000 s.
T346 46063-46190 Sentence denotes The data were baseline subtracted prior to fitting performed using a 1:1 binding model and the ForteBio data analysis software.
T347 46191-46267 Sentence denotes Mean kon, koff values were determined with a global fit applied to all data.
T348 46268-46419 Sentence denotes The experiments were done with two separate purification batches of SARS-CoV SB, SARS-CoV-2-SB, and ACE2 each in duplicate and the average is reported.
T349 46421-46456 Sentence denotes Protein expression and purification
T350 46457-46845 Sentence denotes The SARS-CoV-2 2P S (GenBank: YP_009724390.1) ectodomain was produced in 500mL HEK293F cells grown in suspension using FreeStyle 293 expression medium (Life technologies) at 37°C in a humidified 8% CO2 incubator rotating at 130 rpm The culture was transfected using 293fectin (ThermoFisher Scientific) with cells grown to a density of 1 million cells per mL and cultivated for three days.
T351 46846-46944 Sentence denotes The supernatant was harvested and cells resuspended for another three days, yielding two harvests.
T352 46945-47026 Sentence denotes Clarified supernatants were purified using a 5mL Cobalt affinity column (Takara).
T353 47027-47172 Sentence denotes Purified protein was filtered or concentrated and flash frozen in a buffer containing 20 mM Tris pH 8.0 and 150 mM NaCl prior to cryoEM analysis.
T354 47174-47219 Sentence denotes CryoEM sample preparation and data collection
T355 47220-47524 Sentence denotes 3 μL of 0.16 mg/mL SARS-CoV-2 S was loaded onto a freshly glow discharged (30 s at 20 mA) lacey carbon grid with a thin layer of evaporated continuous carbon prior to plunge freezing using a vitrobot MarkIV (ThermoFisher Scientific) using a blot force of −1 and 2.5 s blot time at 100% humidity and 25°C.
T356 47525-47819 Sentence denotes Data were acquired using the Leginon software (Suloway et al., 2005) to control an FEI Titan Krios transmission electron microscope operated at 300 kV and equipped with a Gatan K2 Summit direct detector and Gatan Quantum GIF energy filter, operated in zero-loss mode with a slit width of 20 eV.
T357 47820-47944 Sentence denotes Automated data collection was carried out using Leginon at a nominal magnification of 130,000x with a pixel size of 0.525 Å.
T358 47945-48082 Sentence denotes The dose rate was adjusted to 8 counts/pixel/s, and each movie was acquired in super-resolution mode fractionated in 50 frames of 200 ms.
T359 48083-48190 Sentence denotes 4,500 micrographs were collected in a single session with a defocus range comprised between 1.0 and 2.5 μm.
T360 48192-48215 Sentence denotes Cryo-EM data processing
T361 48216-48394 Sentence denotes Movie frame alignment, estimation of the microscope contrast-transfer function parameters, particle picking and extraction were carried out using Warp (Tegunov and Cramer, 2019).
T362 48395-48495 Sentence denotes Particle images were extracted with a box size of 800 binned to 400 yielding a pixel size of 1.05 Å.
T363 48496-48653 Sentence denotes For each dataset two rounds of reference-free 2D classification were performed using cryoSPARC (Punjani et al., 2017) to select well-defined particle images.
T364 48654-48938 Sentence denotes Subsequently, two rounds of 3D classification with 50 iterations each (angular sampling 7.5° for 25 iterations and 1.8° with local search for 25 iterations) were carried out using Relion (Zivanov et al., 2018) without imposing symmetry to separate distinct SARS-CoV-2 S conformations.
T365 48939-49130 Sentence denotes 3D refinements were carried out using non-uniform refinement along with per-particle defocus refinement in cryoSPARC (Punjani et al., 2017) using an ab initio model generated using cryoSPARC.
T366 49131-49378 Sentence denotes Particle images were subjected to Bayesian polishing (Zivanov et al., 2019) before performing another round of non-uniform refinement in cryoSPARC (Punjani et al., 2017) followed by per-particle defocus refinement and again non-uniform refinement.
T367 49379-49465 Sentence denotes Local resolution estimation, filtering and sharpening was carried out using CryoSPARC.
T368 49466-49716 Sentence denotes Reported resolutions are based on the gold-standard Fourier shell correlation (FSC) of 0.143 criterion and Fourier shell correlation curves were corrected for the effects of soft masking by high-resolution noise substitution (Scheres and Chen, 2012).
T369 49718-49752 Sentence denotes CryoEM model building and analysis
T370 49753-49860 Sentence denotes UCSF Chimera (Goddard et al., 2007) and Coot were used to fit atomic models (PDB 6NB6) into the cryoEM map.
T371 49861-49985 Sentence denotes The model was subsequently manually rebuilt using Coot and the C3-symmetrized map (Brown et al., 2015, Emsley et al., 2010).
T372 49986-50052 Sentence denotes This model was then used to build features specific of the C1-map.
T373 50053-50191 Sentence denotes N-linked glycans were hand-built into the density where visible and the models were refined and relaxed using Rosetta (Wang et al., 2016).
T374 50192-50433 Sentence denotes Glycan refinement relied on a dedicated Rosetta protocol, which uses physically realistic geometries based on prior knowledge of saccharide chemical properties (Frenz et al., 2019), and was aided by using both sharpened and unsharpened maps.
T375 50434-50678 Sentence denotes Models were analyzed using MolProbity (Chen et al., 2010), EMringer (Barad et al., 2015), Phenix (Liebschner et al., 2019) and privateer (Agirre et al., 2015) to validate the stereochemistry of both the protein and glycan components (Table S1).
T376 50679-50782 Sentence denotes Figures were generated using UCSF ChimeraX (Goddard et al., 2018) and consurf (Ashkenazy et al., 2016).
T377 50784-50813 Sentence denotes Immunizations with SARS-CoV S
T378 50814-50967 Sentence denotes 57BL/6J mice were obtained from the Jackson Laboratory and maintained at the Comparative Medicine Facility at the Fred Hutchinson Cancer Research Center.
T379 50968-51304 Sentence denotes After collecting a pre-bleed, mice were immunized with 5μg of SARS-CoV 2P S ectodomain trimer (this construct was previously described (Walls et al., 2019)) formulated in 50μl of PBS and 50μl of Sigma Adjuvant System subcutaneously in the base of the tail at weeks 0, 4, and 12 and bleeds were collected 2 weeks after each immunization.
T380 51305-51405 Sentence denotes Plasma from immunized animals was heat inactivated at 56°C for 1 h and then stored at 4°C until use.
T381 51406-51559 Sentence denotes All experiments were conducted at the Fred Hutchinson Cancer Research Center according to approved Institutional Animal Care and Use Committee protocols.
T382 51561-51600 Sentence denotes Quantification and Statistical Analysis
T383 51601-51738 Sentence denotes Western-blots and biolayer interferometry assays were performed multiple times with at least two independent preparations of each sample.
T384 51739-51834 Sentence denotes No methods were used to determine whether the data met assumptions of the statistical approach.
T385 51836-51862 Sentence denotes Data and Code Availability
T386 51863-52005 Sentence denotes The cryoEM maps and atomic models have been deposited at the Electron Microscopy Data Bank and the Protein Data Bank with accession codes EMD:
T387 52006-52020 Sentence denotes 21452 and PDB:
T388 52021-52064 Sentence denotes 6VXX (closed SARS-CoV-2 S), as well as EMD:
T389 52065-52079 Sentence denotes 21457 and PDB:
T390 52080-52117 Sentence denotes 6VYB (SARS-CoV-2 S with one SB open).
T391 52118-52196 Sentence denotes A list of software used in this study can be found in the Key Resources Table.
T392 52198-52222 Sentence denotes Supplemental Information
T393 52223-52232 Sentence denotes Table S1.
T394 52233-52314 Sentence denotes Cryo-EM Data Collection and Refinement Statistics, Related to Figures 3, 4, and 5
T395 52315-52323 Sentence denotes Data S1.
T396 52324-52417 Sentence denotes Amino Acid Sequence Alignment of Sarbecovirus S Glycoproteins, Related to Figures 1, 2, and 5
T397 52418-52813 Sentence denotes The following sequences were used: SARS-CoV-2 (YP_009724390.1), SARSr-CoV RaTG13 (QHR63300.2), SARS-CoV Urbani (AAP13441.1), SARS-CoV CUHK-W1 (AAP13567.1), SARS-CoV GZ02 (AAS00003.1), SARS-CoV A031 (AAV97988.1), SARS-CoV A022 (AAV91631.1), WIV-16 (ALK02457.1), WIV-1 (AGZ48828.1), SARSr-CoV ZXC21 (AVP78042.1), SARSr-CoV ZC45 (AVP78031.1), SARSr-CoV Rp3 (Q3I5J5.1), SARSr-CoV Rs672 (ACU31032.1).
T398 52815-52830 Sentence denotes Acknowledgments
T399 52831-53378 Sentence denotes This study was supported by the 10.13039/100000057National Institute of General Medical Sciences (R01GM120553 to D.V.), the 10.13039/100000060National Institute of Allergy and Infectious Diseases (HHSN272201700059C to D.V.), a Pew Biomedical Scholars Award (D.V.), an Investigators in the Pathogenesis of Infectious Disease Award from the 10.13039/100000861Burroughs Wellcome Fund (D.V.), the 10.13039/100007812University of Washington Arnold and Mabel Beckman cryoEM center, the Washington Research Foundation, and the Pasteur Institute (M.A.T.).
T400 53379-53564 Sentence denotes We are grateful to Lynda Stuart for sharing the full-length hACE2 plasmid, to Gary Whittaker for the MLV pseudotyping system, and to Ning Zheng for providing access to the Octet device.
T401 53566-53586 Sentence denotes Author Contributions
T402 53587-53646 Sentence denotes A.C.W., Y.-J.P., A.T.M., and D.V. designed the experiments.
T403 53647-53701 Sentence denotes A.C.W. and M.A.T. expressed and purified the proteins.
T404 53702-53765 Sentence denotes A.C.W. carried out binding assays and pseudovirus entry assays.
T405 53766-53826 Sentence denotes Y.-J.P. prepared samples for cryo-EM and collected the data.
T406 53827-53903 Sentence denotes Y.-J.P. and D.V. processed the data and built and refined the atomic models.
T407 53904-53935 Sentence denotes A.W. and A.T.M. immunized mice.
T408 53936-54036 Sentence denotes A.C.W., Y.-J.P., and D.V. analyzed the data and prepared the manuscript with input from all authors.
T409 54038-54062 Sentence denotes Declaration of Interests
T410 54063-54116 Sentence denotes The authors declare no competing financial interests.
T411 54117-54208 Sentence denotes Supplemental Information can be found online at https://doi.org/10.1016/j.cell.2020.02.058.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 1880-1889 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T2 2804-2813 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T3 11116-11124 Phenotype denotes leukemia http://purl.obolibrary.org/obo/HP_0001909
T4 37704-37712 Phenotype denotes leukemia http://purl.obolibrary.org/obo/HP_0001909
T5 50944-50950 Phenotype denotes Cancer http://purl.obolibrary.org/obo/HP_0002664
T6 51460-51466 Phenotype denotes Cancer http://purl.obolibrary.org/obo/HP_0002664
T7 52995-53002 Phenotype denotes Allergy http://purl.obolibrary.org/obo/HP_0012393

2_test

Id Subject Object Predicate Lexical cue
32155444-12690091-131523131 2015-2019 12690091 denotes 2003
32155444-12690091-131523131 2015-2019 12690091 denotes 2003
32155444-12690092-131523132 2037-2041 12690092 denotes 2003
32155444-12690092-131523132 2037-2041 12690092 denotes 2003
32155444-23075143-131523133 2103-2107 23075143 denotes 2012
32155444-23075143-131523133 2103-2107 23075143 denotes 2012
32155444-31978945-131523134 2169-2173 31978945 denotes 2020
32155444-31978945-131523134 2169-2173 31978945 denotes 2020
32155444-31978945-131523135 2735-2739 31978945 denotes 2020
32155444-31978945-131523135 2735-2739 31978945 denotes 2020
32155444-24355866-131523136 3233-3237 24355866 denotes 2014
32155444-24355866-131523136 3233-3237 24355866 denotes 2014
32155444-24206838-131523137 3254-3258 24206838 denotes 2013
32155444-24206838-131523137 3254-3258 24206838 denotes 2013
32155444-24172901-131523138 3408-3412 24172901 denotes 2013
32155444-24172901-131523138 3408-3412 24172901 denotes 2013
32155444-29190287-131523139 3425-3429 29190287 denotes 2017
32155444-29190287-131523139 3425-3429 29190287 denotes 2017
32155444-12958366-131523141 3644-3648 12958366 denotes 2003
32155444-12958366-131523141 3644-3648 12958366 denotes 2003
32155444-16140765-131523142 3662-3666 16140765 denotes 2005
32155444-16140765-131523142 3662-3666 16140765 denotes 2005
32155444-16485471-131523143 3681-3685 16485471 denotes 2005
32155444-16485471-131523143 3681-3685 16485471 denotes 2005
32155444-28377531-131523144 3981-3985 28377531 denotes 2017
32155444-28377531-131523144 3981-3985 28377531 denotes 2017
32155444-24172901-131523145 3998-4002 24172901 denotes 2013
32155444-24172901-131523145 3998-4002 24172901 denotes 2013
32155444-29190287-131523146 4015-4019 29190287 denotes 2017
32155444-29190287-131523146 4015-4019 29190287 denotes 2017
32155444-26552008-131523148 4057-4061 26552008 denotes 2015
32155444-26552008-131523148 4057-4061 26552008 denotes 2015
32155444-26976607-131523149 4081-4085 26976607 denotes 2016
32155444-26976607-131523149 4081-4085 26976607 denotes 2016
32155444-31522710-131523151 4633-4637 31522710 denotes 2019
32155444-31522710-131523151 4633-4637 31522710 denotes 2019
32155444-19321428-131523152 4959-4963 19321428 denotes 2009
32155444-19321428-131523152 4959-4963 19321428 denotes 2009
32155444-12885899-131523153 4979-4983 12885899 denotes 2003
32155444-12885899-131523153 4979-4983 12885899 denotes 2003
32155444-25375324-131523154 5001-5005 25375324 denotes 2014
32155444-25375324-131523154 5001-5005 25375324 denotes 2014
32155444-27791014-131523158 5103-5107 27791014 denotes 2016
32155444-27791014-131523158 5103-5107 27791014 denotes 2016
32155444-28008928-131523160 5334-5338 28008928 denotes 2017
32155444-28008928-131523160 5334-5338 28008928 denotes 2017
32155444-26935699-131523161 5361-5365 26935699 denotes 2016
32155444-26935699-131523161 5361-5365 26935699 denotes 2016
32155444-28807998-131523162 5384-5388 28807998 denotes 2017
32155444-28807998-131523162 5384-5388 28807998 denotes 2017
32155444-30102747-131523163 5403-5407 30102747 denotes 2018
32155444-30102747-131523163 5403-5407 30102747 denotes 2018
32155444-28393837-131523166 5464-5468 28393837 denotes 2017
32155444-28393837-131523166 5464-5468 28393837 denotes 2017
32155444-19439480-131523167 5615-5619 19439480 denotes 2009
32155444-19439480-131523167 5615-5619 19439480 denotes 2009
32155444-25445340-131523168 5643-5647 25445340 denotes 2015
32155444-25445340-131523168 5643-5647 25445340 denotes 2015
32155444-19321428-131523169 5795-5799 19321428 denotes 2009
32155444-19321428-131523169 5795-5799 19321428 denotes 2009
32155444-22590686-131523170 5830-5834 22590686 denotes 2012
32155444-22590686-131523170 5830-5834 22590686 denotes 2012
32155444-25288733-131523171 5858-5862 25288733 denotes 2014
32155444-25288733-131523171 5858-5862 25288733 denotes 2014
32155444-25445340-131523172 5886-5889 25445340 denotes 201
32155444-25445340-131523172 5886-5889 25445340 denotes 201
32155444-27791014-131523173 5905-5909 27791014 denotes 2016
32155444-27791014-131523173 5905-5909 27791014 denotes 2016
32155444-30679277-131523175 6525-6529 30679277 denotes 2019
32155444-30679277-131523175 6525-6529 30679277 denotes 2019
32155444-31522710-131523176 6549-6553 31522710 denotes 2019
32155444-31522710-131523176 6549-6553 31522710 denotes 2019
32155444-3380803-131523177 6570-6574 3380803 denotes 1988
32155444-3380803-131523177 6570-6574 3380803 denotes 1988
32155444-28923942-131523178 6683-6687 28923942 denotes 2017
32155444-28923942-131523178 6683-6687 28923942 denotes 2017
32155444-31792450-131523179 6702-6706 31792450 denotes 2019
32155444-31792450-131523179 6702-6706 31792450 denotes 2019
32155444-23831647-131523180 6824-6828 23831647 denotes 2013
32155444-23831647-131523180 6824-6828 23831647 denotes 2013
32155444-23486063-131523181 6842-6846 23486063 denotes 2013
32155444-23486063-131523181 6842-6846 23486063 denotes 2013
32155444-24172901-131523182 7012-7016 24172901 denotes 2013
32155444-24172901-131523182 7012-7016 24172901 denotes 2013
32155444-30356097-131523183 7039-7043 30356097 denotes 2018
32155444-30356097-131523183 7039-7043 30356097 denotes 2018
32155444-14647384-131523185 7074-7078 14647384 denotes 2003
32155444-14647384-131523185 7074-7078 14647384 denotes 2003
32155444-30102747-131523186 7093-7097 30102747 denotes 2018
32155444-30102747-131523186 7093-7097 30102747 denotes 2018
32155444-9420251-131523188 7440-7444 9420251 denotes 1998
32155444-9420251-131523188 7440-7444 9420251 denotes 1998
32155444-30712865-131523190 7554-7558 30712865 denotes 2019
32155444-30712865-131523190 7554-7558 30712865 denotes 2019
32155444-29093093-131523191 7574-7578 29093093 denotes 2018
32155444-29093093-131523191 7574-7578 29093093 denotes 2018
32155444-15247913-131523193 7740-7744 15247913 denotes 2004
32155444-15247913-131523193 7740-7744 15247913 denotes 2004
32155444-26216974-131523194 7773-7777 26216974 denotes 2015
32155444-26216974-131523194 7773-7777 26216974 denotes 2015
32155444-30712865-131523195 7956-7960 30712865 denotes 2019
32155444-30712865-131523195 7956-7960 30712865 denotes 2019
32155444-30712865-131523196 8228-8232 30712865 denotes 2019
32155444-30712865-131523196 8228-8232 30712865 denotes 2019
32155444-8162439-131523197 9207-9211 8162439 denotes 1994
32155444-8162439-131523197 9207-9211 8162439 denotes 1994
32155444-10329563-131523198 9225-9229 10329563 denotes 1999
32155444-10329563-131523198 9225-9229 10329563 denotes 1999
32155444-24172901-131523199 10122-10126 24172901 denotes 2013
32155444-24172901-131523199 10122-10126 24172901 denotes 2013
32155444-14647384-131523202 10659-10663 14647384 denotes 2003
32155444-14647384-131523202 10659-10663 14647384 denotes 2003
32155444-19321428-131523204 10886-10890 19321428 denotes 2009
32155444-19321428-131523204 10886-10890 19321428 denotes 2009
32155444-18562523-131523205 10906-10910 18562523 denotes 2008
32155444-18562523-131523205 10906-10910 18562523 denotes 2008
32155444-21325420-131523206 10929-10933 21325420 denotes 2011
32155444-21325420-131523206 10929-10933 21325420 denotes 2011
32155444-20926566-131523207 10953-10957 20926566 denotes 2010
32155444-20926566-131523207 10953-10957 20926566 denotes 2010
32155444-25445340-131523208 10981-10985 25445340 denotes 2015
32155444-25445340-131523208 10981-10985 25445340 denotes 2015
32155444-21068237-131523209 11002-11006 21068237 denotes 2011
32155444-21068237-131523209 11002-11006 21068237 denotes 2011
32155444-12690091-131523210 11431-11435 12690091 denotes 2003
32155444-12690091-131523210 11431-11435 12690091 denotes 2003
32155444-12690092-131523211 11453-11457 12690092 denotes 2003
32155444-12690092-131523211 11453-11457 12690092 denotes 2003
32155444-19321428-131523212 14469-14473 19321428 denotes 2009
32155444-19321428-131523212 14469-14473 19321428 denotes 2009
32155444-18562523-131523213 14489-14493 18562523 denotes 2008
32155444-18562523-131523213 14489-14493 18562523 denotes 2008
32155444-21325420-131523214 14512-14516 21325420 denotes 2011
32155444-21325420-131523214 14512-14516 21325420 denotes 2011
32155444-20926566-131523215 14536-14540 20926566 denotes 2010
32155444-20926566-131523215 14536-14540 20926566 denotes 2010
32155444-25445340-131523216 14564-14568 25445340 denotes 2015
32155444-25445340-131523216 14564-14568 25445340 denotes 2015
32155444-21068237-131523217 14585-14589 21068237 denotes 2011
32155444-21068237-131523217 14585-14589 21068237 denotes 2011
32155444-8162439-131523218 15417-15421 8162439 denotes 1994
32155444-8162439-131523218 15417-15421 8162439 denotes 1994
32155444-25445340-131523219 15445-15449 25445340 denotes 2015
32155444-25445340-131523219 15445-15449 25445340 denotes 2015
32155444-10329563-131523220 15463-15467 10329563 denotes 1999
32155444-10329563-131523220 15463-15467 10329563 denotes 1999
32155444-12958366-131523221 15721-15725 12958366 denotes 2003
32155444-12958366-131523221 15721-15725 12958366 denotes 2003
32155444-15452268-131523222 15738-15742 15452268 denotes 2004
32155444-15452268-131523222 15738-15742 15452268 denotes 2004
32155444-14752165-131523224 15980-15984 14752165 denotes 2004
32155444-14752165-131523224 15980-15984 14752165 denotes 2004
32155444-16140765-131523225 15998-16002 16140765 denotes 2005
32155444-16140765-131523225 15998-16002 16140765 denotes 2005
32155444-14983044-131523227 16034-16038 14983044 denotes 2004
32155444-14983044-131523227 16034-16038 14983044 denotes 2004
32155444-14752165-131523228 16215-16219 14752165 denotes 2004
32155444-14752165-131523228 16215-16219 14752165 denotes 2004
32155444-16140765-131523229 16233-16237 16140765 denotes 2005
32155444-16140765-131523229 16233-16237 16140765 denotes 2005
32155444-30356097-131523231 17115-17119 30356097 denotes 2018
32155444-30356097-131523231 17115-17119 30356097 denotes 2018
32155444-14983044-131523233 17151-17155 14983044 denotes 2004
32155444-14983044-131523233 17151-17155 14983044 denotes 2004
32155444-30712865-131523234 17171-17175 30712865 denotes 2019
32155444-30712865-131523234 17171-17175 30712865 denotes 2019
32155444-14670965-131523235 17190-17194 14670965 denotes 2004
32155444-14670965-131523235 17190-17194 14670965 denotes 2004
32155444-31565258-20753276 17555-17559 31565258 denotes 2017
32155444-31565258-20753276 17555-17559 31565258 denotes 2017
32155444-31522710-131523237 20331-20335 31522710 denotes 2019
32155444-31522710-131523237 20331-20335 31522710 denotes 2019
32155444-30712865-131523240 20393-20397 30712865 denotes 2019
32155444-30712865-131523240 20393-20397 30712865 denotes 2019
32155444-30356097-131523241 20468-20472 30356097 denotes 2018
32155444-30356097-131523241 20468-20472 30356097 denotes 2018
32155444-28807998-131523242 20491-20495 28807998 denotes 2017
32155444-28807998-131523242 20491-20495 28807998 denotes 2017
32155444-9680195-131523243 20564-20568 9680195 denotes 1998
32155444-9680195-131523243 20564-20568 9680195 denotes 1998
32155444-28008928-131523244 21425-21429 28008928 denotes 2017
32155444-28008928-131523244 21425-21429 28008928 denotes 2017
32155444-30356097-131523245 21452-21456 30356097 denotes 2018
32155444-30356097-131523245 21452-21456 30356097 denotes 2018
32155444-28807998-131523246 21475-21479 28807998 denotes 2017
32155444-28807998-131523246 21475-21479 28807998 denotes 2017
32155444-30102747-131523247 21494-21498 30102747 denotes 2018
32155444-30102747-131523247 21494-21498 30102747 denotes 2018
32155444-30712865-131523248 21514-21518 30712865 denotes 2019
32155444-30712865-131523248 21514-21518 30712865 denotes 2019
32155444-28393837-131523249 21533-21537 28393837 denotes 2017
32155444-28393837-131523249 21533-21537 28393837 denotes 2017
32155444-28008928-131523250 22429-22433 28008928 denotes 2017
32155444-28008928-131523250 22429-22433 28008928 denotes 2017
32155444-30356097-131523251 22456-22460 30356097 denotes 2018
32155444-30356097-131523251 22456-22460 30356097 denotes 2018
32155444-30102747-131523252 22475-22479 30102747 denotes 2018
32155444-30102747-131523252 22475-22479 30102747 denotes 2018
32155444-30712865-131523253 22495-22499 30712865 denotes 2019
32155444-30712865-131523253 22495-22499 30712865 denotes 2019
32155444-28393837-131523254 22514-22518 28393837 denotes 2017
32155444-28393837-131523254 22514-22518 28393837 denotes 2017
32155444-28008928-131523255 23888-23892 28008928 denotes 2017
32155444-28008928-131523255 23888-23892 28008928 denotes 2017
32155444-30356097-131523256 23915-23919 30356097 denotes 2018
32155444-30356097-131523256 23915-23919 30356097 denotes 2018
32155444-28807998-131523257 23938-23942 28807998 denotes 2017
32155444-28807998-131523257 23938-23942 28807998 denotes 2017
32155444-31792450-131523258 23957-23961 31792450 denotes 2019
32155444-31792450-131523258 23957-23961 31792450 denotes 2019
32155444-30102747-131523259 23976-23980 30102747 denotes 2018
32155444-30102747-131523259 23976-23980 30102747 denotes 2018
32155444-31522710-131523260 24000-24004 31522710 denotes 2019
32155444-31522710-131523260 24000-24004 31522710 denotes 2019
32155444-30712865-131523263 24062-24066 30712865 denotes 2019
32155444-30712865-131523263 24062-24066 30712865 denotes 2019
32155444-28393837-131523264 24081-24085 28393837 denotes 2017
32155444-28393837-131523264 24081-24085 28393837 denotes 2017
32155444-28008928-131523266 24611-24615 28008928 denotes 2017
32155444-28008928-131523266 24611-24615 28008928 denotes 2017
32155444-30356097-131523267 24638-24642 30356097 denotes 2018
32155444-30356097-131523267 24638-24642 30356097 denotes 2018
32155444-25288733-131523268 24666-24670 25288733 denotes 2014
32155444-25288733-131523268 24666-24670 25288733 denotes 2014
32155444-28807998-131523269 24689-24693 28807998 denotes 2017
32155444-28807998-131523269 24689-24693 28807998 denotes 2017
32155444-27791014-131523270 24708-24712 27791014 denotes 2016
32155444-27791014-131523270 24708-24712 27791014 denotes 2016
32155444-30102747-131523271 24727-24731 30102747 denotes 2018
32155444-30102747-131523271 24727-24731 30102747 denotes 2018
32155444-30712865-131523272 24747-24751 30712865 denotes 2019
32155444-30712865-131523272 24747-24751 30712865 denotes 2019
32155444-28393837-131523273 24766-24770 28393837 denotes 2017
32155444-28393837-131523273 24766-24770 28393837 denotes 2017
32155444-30712865-131523275 25584-25588 30712865 denotes 2019
32155444-30712865-131523275 25584-25588 30712865 denotes 2019
32155444-29093093-131523276 25604-25608 29093093 denotes 2018
32155444-29093093-131523276 25604-25608 29093093 denotes 2018
32155444-9420251-131523277 25675-25679 9420251 denotes 1998
32155444-9420251-131523277 25675-25679 9420251 denotes 1998
32155444-28807998-131523279 25795-25799 28807998 denotes 2017
32155444-28807998-131523279 25795-25799 28807998 denotes 2017
32155444-30712865-131523280 25815-25819 30712865 denotes 2019
32155444-30712865-131523280 25815-25819 30712865 denotes 2019
32155444-30712865-131523281 26163-26167 30712865 denotes 2019
32155444-30712865-131523281 26163-26167 30712865 denotes 2019
32155444-24172901-131523282 27980-27984 24172901 denotes 2013
32155444-24172901-131523282 27980-27984 24172901 denotes 2013
32155444-18077725-131523283 27998-28002 18077725 denotes 2008
32155444-18077725-131523283 27998-28002 18077725 denotes 2008
32155444-14752165-131523286 30157-30161 14752165 denotes 2004
32155444-14752165-131523286 30157-30161 14752165 denotes 2004
32155444-16140765-131523287 30175-30179 16140765 denotes 2005
32155444-16140765-131523287 30175-30179 16140765 denotes 2005
32155444-18448527-131523289 30394-30398 18448527 denotes 2008
32155444-18448527-131523289 30394-30398 18448527 denotes 2008
32155444-15452268-131523290 30411-30415 15452268 denotes 2004
32155444-15452268-131523290 30411-30415 15452268 denotes 2004
32155444-25445340-20753331 30928-30932 25445340 denotes 2015
32155444-25445340-20753331 30928-30932 25445340 denotes 2015
32155444-25211075-131523291 31205-31209 25211075 denotes 2014
32155444-25211075-131523291 31205-31209 25211075 denotes 2014
32155444-25114257-131523292 31224-31228 25114257 denotes 2014
32155444-25114257-131523292 31224-31228 25114257 denotes 2014
32155444-8162439-131523294 31660-31664 8162439 denotes 1994
32155444-8162439-131523294 31660-31664 8162439 denotes 1994
32155444-10329563-131523295 31678-31682 10329563 denotes 1999
32155444-10329563-131523295 31678-31682 10329563 denotes 1999
32155444-19321428-131523296 32002-32006 19321428 denotes 2009
32155444-19321428-131523296 32002-32006 19321428 denotes 2009
32155444-18562523-131523297 32022-32026 18562523 denotes 2008
32155444-18562523-131523297 32022-32026 18562523 denotes 2008
32155444-21325420-131523298 32045-32049 21325420 denotes 2011
32155444-21325420-131523298 32045-32049 21325420 denotes 2011
32155444-20926566-131523299 32069-32073 20926566 denotes 2010
32155444-20926566-131523299 32069-32073 20926566 denotes 2010
32155444-25445340-131523300 32097-32101 25445340 denotes 2015
32155444-25445340-131523300 32097-32101 25445340 denotes 2015
32155444-21068237-131523301 32118-32122 21068237 denotes 2011
32155444-21068237-131523301 32118-32122 21068237 denotes 2011
32155444-30712865-131523303 32556-32560 30712865 denotes 2019
32155444-30712865-131523303 32556-32560 30712865 denotes 2019
32155444-29093093-131523304 32576-32580 29093093 denotes 2018
32155444-29093093-131523304 32576-32580 29093093 denotes 2018
32155444-28008928-131523305 32635-32639 28008928 denotes 2017
32155444-28008928-131523305 32635-32639 28008928 denotes 2017
32155444-30356097-131523306 32662-32666 30356097 denotes 2018
32155444-30356097-131523306 32662-32666 30356097 denotes 2018
32155444-28807998-131523307 32685-32689 28807998 denotes 2017
32155444-28807998-131523307 32685-32689 28807998 denotes 2017
32155444-30102747-131523308 32704-32708 30102747 denotes 2018
32155444-30102747-131523308 32704-32708 30102747 denotes 2018
32155444-30712865-131523309 32724-32728 30712865 denotes 2019
32155444-30712865-131523309 32724-32728 30712865 denotes 2019
32155444-28393837-131523310 32743-32747 28393837 denotes 2017
32155444-28393837-131523310 32743-32747 28393837 denotes 2017
32155444-30102747-131523311 33044-33048 30102747 denotes 2018
32155444-30102747-131523311 33044-33048 30102747 denotes 2018
32155444-30712865-131523313 33085-33089 30712865 denotes 2019
32155444-30712865-131523313 33085-33089 30712865 denotes 2019
32155444-31522710-131523315 33258-33262 31522710 denotes 2019
32155444-31522710-131523315 33258-33262 31522710 denotes 2019
32155444-26935699-131523316 33297-33301 26935699 denotes 2016
32155444-26935699-131523316 33297-33301 26935699 denotes 2016
32155444-31650956-131523317 33330-33334 31650956 denotes 2019
32155444-31650956-131523317 33330-33334 31650956 denotes 2019
32155444-29170370-131523318 33427-33431 29170370 denotes 2017
32155444-29170370-131523318 33427-33431 29170370 denotes 2017
32155444-19901337-131523319 33444-33448 19901337 denotes 2009
32155444-19901337-131523319 33444-33448 19901337 denotes 2009
32155444-31650956-131523320 33610-33614 31650956 denotes 2019
32155444-31650956-131523320 33610-33614 31650956 denotes 2019
32155444-12958366-131523323 34374-34378 12958366 denotes 2003
32155444-12958366-131523323 34374-34378 12958366 denotes 2003
32155444-15452268-131523324 34391-34395 15452268 denotes 2004
32155444-15452268-131523324 34391-34395 15452268 denotes 2004
32155444-32065055-131523326 35259-35263 32065055 denotes 2020
32155444-32065055-131523326 35259-35263 32065055 denotes 2020
32155444-15194770-131523327 35394-35398 15194770 denotes 2004
32155444-15194770-131523327 35394-35398 15194770 denotes 2004
32155444-16954221-131523328 35573-35577 16954221 denotes 2006
32155444-16954221-131523328 35573-35577 16954221 denotes 2006
32155444-18199635-131523329 35593-35597 18199635 denotes 2008
32155444-18199635-131523329 35593-35597 18199635 denotes 2008
32155444-20144042-131523330 35613-35617 20144042 denotes 2010
32155444-20144042-131523330 35613-35617 20144042 denotes 2010
32155444-15247913-131523331 35636-35640 15247913 denotes 2004
32155444-15247913-131523331 35636-35640 15247913 denotes 2004
32155444-30712865-131523332 35656-35660 30712865 denotes 2019
32155444-30712865-131523332 35656-35660 30712865 denotes 2019
32155444-30712865-131523333 40226-40230 30712865 denotes 2019
32155444-30712865-131523333 40226-40230 30712865 denotes 2019
32155444-30712865-131523334 41669-41673 30712865 denotes 2019
32155444-30712865-131523334 41669-41673 30712865 denotes 2019
32155444-15890530-131523335 47588-47592 15890530 denotes 2005
32155444-15890530-131523335 47588-47592 15890530 denotes 2005
32155444-31591575-131523336 48388-48392 31591575 denotes 2019
32155444-31591575-131523336 48388-48392 31591575 denotes 2019
32155444-28165473-131523337 48608-48612 28165473 denotes 2017
32155444-28165473-131523337 48608-48612 28165473 denotes 2017
32155444-30412051-131523338 48858-48862 30412051 denotes 2018
32155444-30412051-131523338 48858-48862 30412051 denotes 2018
32155444-28165473-131523339 49073-49077 28165473 denotes 2017
32155444-28165473-131523339 49073-49077 28165473 denotes 2017
32155444-28165473-131523340 49295-49299 28165473 denotes 2017
32155444-28165473-131523340 49295-49299 28165473 denotes 2017
32155444-22842542-131523341 49710-49714 22842542 denotes 2012
32155444-22842542-131523341 49710-49714 22842542 denotes 2012
32155444-16963278-131523342 49783-49787 16963278 denotes 2007
32155444-16963278-131523342 49783-49787 16963278 denotes 2007
32155444-25615868-131523343 49958-49962 25615868 denotes 2015
32155444-25615868-131523343 49958-49962 25615868 denotes 2015
32155444-20383002-131523344 49979-49983 20383002 denotes 2010
32155444-20383002-131523344 49979-49983 20383002 denotes 2010
32155444-27669148-131523345 50185-50189 27669148 denotes 2016
32155444-27669148-131523345 50185-50189 27669148 denotes 2016
32155444-30344107-131523346 50367-50371 30344107 denotes 2019
32155444-30344107-131523346 50367-50371 30344107 denotes 2019
32155444-20057044-131523347 50486-50490 20057044 denotes 2010
32155444-20057044-131523347 50486-50490 20057044 denotes 2010
32155444-26280328-131523348 50517-50521 26280328 denotes 2015
32155444-26280328-131523348 50517-50521 26280328 denotes 2015
32155444-26581513-131523349 50587-50591 26581513 denotes 2015
32155444-26581513-131523349 50587-50591 26581513 denotes 2015
32155444-28710774-131523350 50739-50743 28710774 denotes 2018
32155444-28710774-131523350 50739-50743 28710774 denotes 2018
32155444-27166375-131523351 50776-50780 27166375 denotes 2016
32155444-27166375-131523351 50776-50780 27166375 denotes 2016
32155444-30712865-131523352 51118-51122 30712865 denotes 2019
32155444-30712865-131523352 51118-51122 30712865 denotes 2019
32155444-12690091-20753170 2015-2019 12690091 denotes 2003
32155444-12690091-20753170 2015-2019 12690091 denotes 2003
32155444-12690092-20753171 2037-2041 12690092 denotes 2003
32155444-12690092-20753171 2037-2041 12690092 denotes 2003
32155444-23075143-20753172 2103-2107 23075143 denotes 2012
32155444-23075143-20753172 2103-2107 23075143 denotes 2012
32155444-31978945-20753173 2169-2173 31978945 denotes 2020
32155444-31978945-20753173 2169-2173 31978945 denotes 2020
32155444-31978945-20753174 2735-2739 31978945 denotes 2020
32155444-31978945-20753174 2735-2739 31978945 denotes 2020
32155444-24355866-20753175 3233-3237 24355866 denotes 2014
32155444-24355866-20753175 3233-3237 24355866 denotes 2014
32155444-24206838-20753176 3254-3258 24206838 denotes 2013
32155444-24206838-20753176 3254-3258 24206838 denotes 2013
32155444-24172901-20753177 3408-3412 24172901 denotes 2013
32155444-24172901-20753177 3408-3412 24172901 denotes 2013
32155444-29190287-20753178 3425-3429 29190287 denotes 2017
32155444-29190287-20753178 3425-3429 29190287 denotes 2017
32155444-12958366-20753180 3644-3648 12958366 denotes 2003
32155444-12958366-20753180 3644-3648 12958366 denotes 2003
32155444-16140765-20753181 3662-3666 16140765 denotes 2005
32155444-16140765-20753181 3662-3666 16140765 denotes 2005
32155444-16485471-20753182 3681-3685 16485471 denotes 2005
32155444-16485471-20753182 3681-3685 16485471 denotes 2005
32155444-28377531-20753183 3981-3985 28377531 denotes 2017
32155444-28377531-20753183 3981-3985 28377531 denotes 2017
32155444-24172901-20753184 3998-4002 24172901 denotes 2013
32155444-24172901-20753184 3998-4002 24172901 denotes 2013
32155444-29190287-20753185 4015-4019 29190287 denotes 2017
32155444-29190287-20753185 4015-4019 29190287 denotes 2017
32155444-26552008-20753187 4057-4061 26552008 denotes 2015
32155444-26552008-20753187 4057-4061 26552008 denotes 2015
32155444-26976607-20753188 4081-4085 26976607 denotes 2016
32155444-26976607-20753188 4081-4085 26976607 denotes 2016
32155444-31522710-20753190 4633-4637 31522710 denotes 2019
32155444-31522710-20753190 4633-4637 31522710 denotes 2019
32155444-19321428-20753191 4959-4963 19321428 denotes 2009
32155444-19321428-20753191 4959-4963 19321428 denotes 2009
32155444-12885899-20753192 4979-4983 12885899 denotes 2003
32155444-12885899-20753192 4979-4983 12885899 denotes 2003
32155444-25375324-20753193 5001-5005 25375324 denotes 2014
32155444-25375324-20753193 5001-5005 25375324 denotes 2014
32155444-26935699-20753194 5028-5032 26935699 denotes 2016
32155444-26935699-20753194 5028-5032 26935699 denotes 2016
32155444-25288733-20753195 5056-5060 25288733 denotes 2014
32155444-25288733-20753195 5056-5060 25288733 denotes 2014
32155444-25445340-20753196 5084-5088 25445340 denotes 2015
32155444-25445340-20753196 5084-5088 25445340 denotes 2015
32155444-27791014-20753197 5103-5107 27791014 denotes 2016
32155444-27791014-20753197 5103-5107 27791014 denotes 2016
32155444-28008928-20753199 5334-5338 28008928 denotes 2017
32155444-28008928-20753199 5334-5338 28008928 denotes 2017
32155444-26935699-20753200 5361-5365 26935699 denotes 2016
32155444-26935699-20753200 5361-5365 26935699 denotes 2016
32155444-28807998-20753201 5384-5388 28807998 denotes 2017
32155444-28807998-20753201 5384-5388 28807998 denotes 2017
32155444-30102747-20753202 5403-5407 30102747 denotes 2018
32155444-30102747-20753202 5403-5407 30102747 denotes 2018
32155444-28393837-20753205 5464-5468 28393837 denotes 2017
32155444-28393837-20753205 5464-5468 28393837 denotes 2017
32155444-19439480-20753206 5615-5619 19439480 denotes 2009
32155444-19439480-20753206 5615-5619 19439480 denotes 2009
32155444-25445340-20753207 5643-5647 25445340 denotes 2015
32155444-25445340-20753207 5643-5647 25445340 denotes 2015
32155444-19321428-20753208 5795-5799 19321428 denotes 2009
32155444-19321428-20753208 5795-5799 19321428 denotes 2009
32155444-22590686-20753209 5830-5834 22590686 denotes 2012
32155444-22590686-20753209 5830-5834 22590686 denotes 2012
32155444-25288733-20753210 5858-5862 25288733 denotes 2014
32155444-25288733-20753210 5858-5862 25288733 denotes 2014
32155444-25445340-20753211 5886-5890 25445340 denotes 2015
32155444-25445340-20753211 5886-5890 25445340 denotes 2015
32155444-27791014-20753212 5905-5909 27791014 denotes 2016
32155444-27791014-20753212 5905-5909 27791014 denotes 2016
32155444-30679277-20753214 6525-6529 30679277 denotes 2019
32155444-30679277-20753214 6525-6529 30679277 denotes 2019
32155444-31160783-20753215 6549-6553 31160783 denotes 2019
32155444-31160783-20753215 6549-6553 31160783 denotes 2019
32155444-3380803-20753216 6570-6574 3380803 denotes 1988
32155444-3380803-20753216 6570-6574 3380803 denotes 1988
32155444-28923942-20753217 6683-6687 28923942 denotes 2017
32155444-28923942-20753217 6683-6687 28923942 denotes 2017
32155444-31792450-20753218 6702-6706 31792450 denotes 2019
32155444-31792450-20753218 6702-6706 31792450 denotes 2019
32155444-23831647-20753219 6824-6828 23831647 denotes 2013
32155444-23831647-20753219 6824-6828 23831647 denotes 2013
32155444-23486063-20753220 6842-6846 23486063 denotes 2013
32155444-23486063-20753220 6842-6846 23486063 denotes 2013
32155444-24172901-20753221 7012-7016 24172901 denotes 2013
32155444-24172901-20753221 7012-7016 24172901 denotes 2013
32155444-30356097-20753222 7039-7043 30356097 denotes 2018
32155444-30356097-20753222 7039-7043 30356097 denotes 2018
32155444-14647384-20753224 7074-7078 14647384 denotes 2003
32155444-14647384-20753224 7074-7078 14647384 denotes 2003
32155444-30102747-20753225 7093-7097 30102747 denotes 2018
32155444-30102747-20753225 7093-7097 30102747 denotes 2018
32155444-9420251-20753227 7440-7444 9420251 denotes 1998
32155444-9420251-20753227 7440-7444 9420251 denotes 1998
32155444-30712865-20753229 7554-7558 30712865 denotes 2019
32155444-30712865-20753229 7554-7558 30712865 denotes 2019
32155444-29093093-20753230 7574-7578 29093093 denotes 2018
32155444-29093093-20753230 7574-7578 29093093 denotes 2018
32155444-15247913-20753232 7740-7744 15247913 denotes 2004
32155444-15247913-20753232 7740-7744 15247913 denotes 2004
32155444-26216974-20753233 7773-7777 26216974 denotes 2015
32155444-26216974-20753233 7773-7777 26216974 denotes 2015
32155444-30712865-20753234 7956-7960 30712865 denotes 2019
32155444-30712865-20753234 7956-7960 30712865 denotes 2019
32155444-30712865-20753235 8228-8232 30712865 denotes 2019
32155444-30712865-20753235 8228-8232 30712865 denotes 2019
32155444-8162439-20753236 9207-9211 8162439 denotes 1994
32155444-8162439-20753236 9207-9211 8162439 denotes 1994
32155444-10329563-20753237 9225-9229 10329563 denotes 1999
32155444-10329563-20753237 9225-9229 10329563 denotes 1999
32155444-24172901-20753238 10122-10126 24172901 denotes 2013
32155444-24172901-20753238 10122-10126 24172901 denotes 2013
32155444-14647384-20753241 10659-10663 14647384 denotes 2003
32155444-14647384-20753241 10659-10663 14647384 denotes 2003
32155444-19321428-20753243 10886-10890 19321428 denotes 2009
32155444-19321428-20753243 10886-10890 19321428 denotes 2009
32155444-18562523-20753244 10906-10910 18562523 denotes 2008
32155444-18562523-20753244 10906-10910 18562523 denotes 2008
32155444-21325420-20753245 10929-10933 21325420 denotes 2011
32155444-21325420-20753245 10929-10933 21325420 denotes 2011
32155444-20926566-20753246 10953-10957 20926566 denotes 2010
32155444-20926566-20753246 10953-10957 20926566 denotes 2010
32155444-25445340-20753247 10981-10985 25445340 denotes 2015
32155444-25445340-20753247 10981-10985 25445340 denotes 2015
32155444-21068237-20753248 11002-11006 21068237 denotes 2011
32155444-21068237-20753248 11002-11006 21068237 denotes 2011
32155444-12690091-20753249 11431-11435 12690091 denotes 2003
32155444-12690091-20753249 11431-11435 12690091 denotes 2003
32155444-12690092-20753250 11453-11457 12690092 denotes 2003
32155444-12690092-20753250 11453-11457 12690092 denotes 2003
32155444-19321428-20753251 14469-14473 19321428 denotes 2009
32155444-19321428-20753251 14469-14473 19321428 denotes 2009
32155444-18562523-20753252 14489-14493 18562523 denotes 2008
32155444-18562523-20753252 14489-14493 18562523 denotes 2008
32155444-21325420-20753253 14512-14516 21325420 denotes 2011
32155444-21325420-20753253 14512-14516 21325420 denotes 2011
32155444-20926566-20753254 14536-14540 20926566 denotes 2010
32155444-20926566-20753254 14536-14540 20926566 denotes 2010
32155444-25445340-20753255 14564-14568 25445340 denotes 2015
32155444-25445340-20753255 14564-14568 25445340 denotes 2015
32155444-21068237-20753256 14585-14589 21068237 denotes 2011
32155444-21068237-20753256 14585-14589 21068237 denotes 2011
32155444-8162439-20753257 15417-15421 8162439 denotes 1994
32155444-8162439-20753257 15417-15421 8162439 denotes 1994
32155444-25445340-20753258 15445-15449 25445340 denotes 2015
32155444-25445340-20753258 15445-15449 25445340 denotes 2015
32155444-10329563-20753259 15463-15467 10329563 denotes 1999
32155444-10329563-20753259 15463-15467 10329563 denotes 1999
32155444-12958366-20753260 15721-15725 12958366 denotes 2003
32155444-12958366-20753260 15721-15725 12958366 denotes 2003
32155444-15452268-20753261 15738-15742 15452268 denotes 2004
32155444-15452268-20753261 15738-15742 15452268 denotes 2004
32155444-14752165-20753263 15980-15984 14752165 denotes 2004
32155444-14752165-20753263 15980-15984 14752165 denotes 2004
32155444-16140765-20753264 15998-16002 16140765 denotes 2005
32155444-16140765-20753264 15998-16002 16140765 denotes 2005
32155444-14983044-20753266 16034-16038 14983044 denotes 2004
32155444-14983044-20753266 16034-16038 14983044 denotes 2004
32155444-14752165-20753267 16215-16219 14752165 denotes 2004
32155444-14752165-20753267 16215-16219 14752165 denotes 2004
32155444-16140765-20753268 16233-16237 16140765 denotes 2005
32155444-16140765-20753268 16233-16237 16140765 denotes 2005
32155444-30356097-20753270 17115-17119 30356097 denotes 2018
32155444-30356097-20753270 17115-17119 30356097 denotes 2018
32155444-14983044-20753272 17151-17155 14983044 denotes 2004
32155444-14983044-20753272 17151-17155 14983044 denotes 2004
32155444-30712865-20753273 17171-17175 30712865 denotes 2019
32155444-30712865-20753273 17171-17175 30712865 denotes 2019
32155444-14670965-20753274 17190-17194 14670965 denotes 2004
32155444-14670965-20753274 17190-17194 14670965 denotes 2004
T29956 17555-17559 31565258 denotes 2017
T30680 17555-17559 31565258 denotes 2017
32155444-31160783-20753277 20331-20335 31160783 denotes 2019
32155444-31160783-20753277 20331-20335 31160783 denotes 2019
32155444-30712865-20753280 20393-20397 30712865 denotes 2019
32155444-30712865-20753280 20393-20397 30712865 denotes 2019
32155444-30356097-20753281 20468-20472 30356097 denotes 2018
32155444-30356097-20753281 20468-20472 30356097 denotes 2018
32155444-28807998-20753282 20491-20495 28807998 denotes 2017
32155444-28807998-20753282 20491-20495 28807998 denotes 2017
32155444-9680195-20753283 20564-20568 9680195 denotes 1998
32155444-9680195-20753283 20564-20568 9680195 denotes 1998
32155444-28008928-20753284 21425-21429 28008928 denotes 2017
32155444-28008928-20753284 21425-21429 28008928 denotes 2017
32155444-30356097-20753285 21452-21456 30356097 denotes 2018
32155444-30356097-20753285 21452-21456 30356097 denotes 2018
32155444-28807998-20753286 21475-21479 28807998 denotes 2017
32155444-28807998-20753286 21475-21479 28807998 denotes 2017
32155444-30102747-20753287 21494-21498 30102747 denotes 2018
32155444-30102747-20753287 21494-21498 30102747 denotes 2018
32155444-30712865-20753288 21514-21518 30712865 denotes 2019
32155444-30712865-20753288 21514-21518 30712865 denotes 2019
32155444-28393837-20753289 21533-21537 28393837 denotes 2017
32155444-28393837-20753289 21533-21537 28393837 denotes 2017
32155444-28008928-20753290 22429-22433 28008928 denotes 2017
32155444-28008928-20753290 22429-22433 28008928 denotes 2017
32155444-30356097-20753291 22456-22460 30356097 denotes 2018
32155444-30356097-20753291 22456-22460 30356097 denotes 2018
32155444-30102747-20753292 22475-22479 30102747 denotes 2018
32155444-30102747-20753292 22475-22479 30102747 denotes 2018
32155444-30712865-20753293 22495-22499 30712865 denotes 2019
32155444-30712865-20753293 22495-22499 30712865 denotes 2019
32155444-28393837-20753294 22514-22518 28393837 denotes 2017
32155444-28393837-20753294 22514-22518 28393837 denotes 2017
32155444-28008928-20753295 23888-23892 28008928 denotes 2017
32155444-28008928-20753295 23888-23892 28008928 denotes 2017
32155444-30356097-20753296 23915-23919 30356097 denotes 2018
32155444-30356097-20753296 23915-23919 30356097 denotes 2018
32155444-28807998-20753297 23938-23942 28807998 denotes 2017
32155444-28807998-20753297 23938-23942 28807998 denotes 2017
32155444-31792450-20753298 23957-23961 31792450 denotes 2019
32155444-31792450-20753298 23957-23961 31792450 denotes 2019
32155444-30102747-20753299 23976-23980 30102747 denotes 2018
32155444-30102747-20753299 23976-23980 30102747 denotes 2018
32155444-31160783-20753300 24000-24004 31160783 denotes 2019
32155444-31160783-20753300 24000-24004 31160783 denotes 2019
32155444-30712865-20753303 24062-24066 30712865 denotes 2019
32155444-30712865-20753303 24062-24066 30712865 denotes 2019
32155444-28393837-20753304 24081-24085 28393837 denotes 2017
32155444-28393837-20753304 24081-24085 28393837 denotes 2017
32155444-28008928-20753306 24611-24615 28008928 denotes 2017
32155444-28008928-20753306 24611-24615 28008928 denotes 2017
32155444-30356097-20753307 24638-24642 30356097 denotes 2018
32155444-30356097-20753307 24638-24642 30356097 denotes 2018
32155444-25288733-20753308 24666-24670 25288733 denotes 2014
32155444-25288733-20753308 24666-24670 25288733 denotes 2014
32155444-28807998-20753309 24689-24693 28807998 denotes 2017
32155444-28807998-20753309 24689-24693 28807998 denotes 2017
32155444-27791014-20753310 24708-24712 27791014 denotes 2016
32155444-27791014-20753310 24708-24712 27791014 denotes 2016
32155444-30102747-20753311 24727-24731 30102747 denotes 2018
32155444-30102747-20753311 24727-24731 30102747 denotes 2018
32155444-30712865-20753312 24747-24751 30712865 denotes 2019
32155444-30712865-20753312 24747-24751 30712865 denotes 2019
32155444-28393837-20753313 24766-24770 28393837 denotes 2017
32155444-28393837-20753313 24766-24770 28393837 denotes 2017
32155444-30712865-20753315 25584-25588 30712865 denotes 2019
32155444-30712865-20753315 25584-25588 30712865 denotes 2019
32155444-29093093-20753316 25604-25608 29093093 denotes 2018
32155444-29093093-20753316 25604-25608 29093093 denotes 2018
32155444-9420251-20753317 25675-25679 9420251 denotes 1998
32155444-9420251-20753317 25675-25679 9420251 denotes 1998
32155444-28807998-20753319 25795-25799 28807998 denotes 2017
32155444-28807998-20753319 25795-25799 28807998 denotes 2017
32155444-30712865-20753320 25815-25819 30712865 denotes 2019
32155444-30712865-20753320 25815-25819 30712865 denotes 2019
32155444-30712865-20753321 26163-26167 30712865 denotes 2019
32155444-30712865-20753321 26163-26167 30712865 denotes 2019
32155444-24172901-20753322 27980-27984 24172901 denotes 2013
32155444-24172901-20753322 27980-27984 24172901 denotes 2013
32155444-18077725-20753323 27998-28002 18077725 denotes 2008
32155444-18077725-20753323 27998-28002 18077725 denotes 2008
32155444-14752165-20753326 30157-30161 14752165 denotes 2004
32155444-14752165-20753326 30157-30161 14752165 denotes 2004
32155444-16140765-20753327 30175-30179 16140765 denotes 2005
32155444-16140765-20753327 30175-30179 16140765 denotes 2005
32155444-18448527-20753329 30394-30398 18448527 denotes 2008
32155444-18448527-20753329 30394-30398 18448527 denotes 2008
32155444-15452268-20753330 30411-30415 15452268 denotes 2004
32155444-15452268-20753330 30411-30415 15452268 denotes 2004
T68153 30928-30932 25445340 denotes 2015
T47488 30928-30932 25445340 denotes 2015
32155444-25211075-20753332 31205-31209 25211075 denotes 2014
32155444-25211075-20753332 31205-31209 25211075 denotes 2014
32155444-25114257-20753333 31224-31228 25114257 denotes 2014
32155444-25114257-20753333 31224-31228 25114257 denotes 2014
32155444-8162439-20753335 31660-31664 8162439 denotes 1994
32155444-8162439-20753335 31660-31664 8162439 denotes 1994
32155444-10329563-20753336 31678-31682 10329563 denotes 1999
32155444-10329563-20753336 31678-31682 10329563 denotes 1999
32155444-19321428-20753337 32002-32006 19321428 denotes 2009
32155444-19321428-20753337 32002-32006 19321428 denotes 2009
32155444-18562523-20753338 32022-32026 18562523 denotes 2008
32155444-18562523-20753338 32022-32026 18562523 denotes 2008
32155444-21325420-20753339 32045-32049 21325420 denotes 2011
32155444-21325420-20753339 32045-32049 21325420 denotes 2011
32155444-20926566-20753340 32069-32073 20926566 denotes 2010
32155444-20926566-20753340 32069-32073 20926566 denotes 2010
32155444-25445340-20753341 32097-32101 25445340 denotes 2015
32155444-25445340-20753341 32097-32101 25445340 denotes 2015
32155444-21068237-20753342 32118-32122 21068237 denotes 2011
32155444-21068237-20753342 32118-32122 21068237 denotes 2011
32155444-30712865-20753344 32556-32560 30712865 denotes 2019
32155444-30712865-20753344 32556-32560 30712865 denotes 2019
32155444-29093093-20753345 32576-32580 29093093 denotes 2018
32155444-29093093-20753345 32576-32580 29093093 denotes 2018
32155444-28008928-20753346 32635-32639 28008928 denotes 2017
32155444-28008928-20753346 32635-32639 28008928 denotes 2017
32155444-30356097-20753347 32662-32666 30356097 denotes 2018
32155444-30356097-20753347 32662-32666 30356097 denotes 2018
32155444-28807998-20753348 32685-32689 28807998 denotes 2017
32155444-28807998-20753348 32685-32689 28807998 denotes 2017
32155444-30102747-20753349 32704-32708 30102747 denotes 2018
32155444-30102747-20753349 32704-32708 30102747 denotes 2018
32155444-30712865-20753350 32724-32728 30712865 denotes 2019
32155444-30712865-20753350 32724-32728 30712865 denotes 2019
32155444-28393837-20753351 32743-32747 28393837 denotes 2017
32155444-28393837-20753351 32743-32747 28393837 denotes 2017
32155444-30102747-20753352 33044-33048 30102747 denotes 2018
32155444-30102747-20753352 33044-33048 30102747 denotes 2018
32155444-30712865-20753354 33085-33089 30712865 denotes 2019
32155444-30712865-20753354 33085-33089 30712865 denotes 2019
32155444-31160783-20753356 33258-33262 31160783 denotes 2019
32155444-31160783-20753356 33258-33262 31160783 denotes 2019
32155444-26935699-20753357 33297-33301 26935699 denotes 2016
32155444-26935699-20753357 33297-33301 26935699 denotes 2016
32155444-31650956-20753358 33330-33334 31650956 denotes 2019
32155444-31650956-20753358 33330-33334 31650956 denotes 2019
32155444-29170370-20753359 33427-33431 29170370 denotes 2017
32155444-29170370-20753359 33427-33431 29170370 denotes 2017
32155444-19901337-20753360 33444-33448 19901337 denotes 2009
32155444-19901337-20753360 33444-33448 19901337 denotes 2009
32155444-31650956-20753361 33610-33614 31650956 denotes 2019
32155444-31650956-20753361 33610-33614 31650956 denotes 2019
32155444-12958366-20753364 34374-34378 12958366 denotes 2003
32155444-12958366-20753364 34374-34378 12958366 denotes 2003
32155444-15452268-20753365 34391-34395 15452268 denotes 2004
32155444-15452268-20753365 34391-34395 15452268 denotes 2004
32155444-32065055-20753367 35259-35263 32065055 denotes 2020
32155444-32065055-20753367 35259-35263 32065055 denotes 2020
32155444-15194770-20753368 35394-35398 15194770 denotes 2004
32155444-15194770-20753368 35394-35398 15194770 denotes 2004
32155444-16954221-20753369 35573-35577 16954221 denotes 2006
32155444-16954221-20753369 35573-35577 16954221 denotes 2006
32155444-18199635-20753370 35593-35597 18199635 denotes 2008
32155444-18199635-20753370 35593-35597 18199635 denotes 2008
32155444-20144042-20753371 35613-35617 20144042 denotes 2010
32155444-20144042-20753371 35613-35617 20144042 denotes 2010
32155444-15247913-20753372 35636-35640 15247913 denotes 2004
32155444-15247913-20753372 35636-35640 15247913 denotes 2004
32155444-30712865-20753373 35656-35660 30712865 denotes 2019
32155444-30712865-20753373 35656-35660 30712865 denotes 2019
32155444-23486063-20753374 37469-37473 23486063 denotes 2013
32155444-23486063-20753374 37469-37473 23486063 denotes 2013
32155444-16963278-20753375 37857-37861 16963278 denotes 2007
32155444-16963278-20753375 37857-37861 16963278 denotes 2007
32155444-28710774-20753376 37927-37931 28710774 denotes 2018
32155444-28710774-20753376 37927-37931 28710774 denotes 2018
32155444-20383002-20753377 37988-37992 20383002 denotes 2010
32155444-20383002-20753377 37988-37992 20383002 denotes 2010
32155444-22842542-20753378 38072-38076 22842542 denotes 2012
32155444-22842542-20753378 38072-38076 22842542 denotes 2012
32155444-30344107-20753379 38192-38196 30344107 denotes 2019
32155444-30344107-20753379 38192-38196 30344107 denotes 2019
32155444-27669148-20753380 38211-38215 27669148 denotes 2016
32155444-27669148-20753380 38211-38215 27669148 denotes 2016
32155444-15890530-20753381 38280-38284 15890530 denotes 2005
32155444-15890530-20753381 38280-38284 15890530 denotes 2005
32155444-31591575-20753382 38378-38382 31591575 denotes 2019
32155444-31591575-20753382 38378-38382 31591575 denotes 2019
32155444-28165473-20753383 38443-38447 28165473 denotes 2017
32155444-28165473-20753383 38443-38447 28165473 denotes 2017
32155444-20057044-20753384 38494-38498 20057044 denotes 2010
32155444-20057044-20753384 38494-38498 20057044 denotes 2010
32155444-30712865-20753385 40226-40230 30712865 denotes 2019
32155444-30712865-20753385 40226-40230 30712865 denotes 2019
32155444-30712865-20753386 41669-41673 30712865 denotes 2019
32155444-30712865-20753386 41669-41673 30712865 denotes 2019
32155444-15890530-20753387 47588-47592 15890530 denotes 2005
32155444-15890530-20753387 47588-47592 15890530 denotes 2005
32155444-31591575-20753388 48388-48392 31591575 denotes 2019
32155444-31591575-20753388 48388-48392 31591575 denotes 2019
32155444-28165473-20753389 48608-48612 28165473 denotes 2017
32155444-28165473-20753389 48608-48612 28165473 denotes 2017
32155444-30412051-20753390 48858-48862 30412051 denotes 2018
32155444-30412051-20753390 48858-48862 30412051 denotes 2018
32155444-28165473-20753391 49073-49077 28165473 denotes 2017
32155444-28165473-20753391 49073-49077 28165473 denotes 2017
32155444-28165473-20753392 49295-49299 28165473 denotes 2017
32155444-28165473-20753392 49295-49299 28165473 denotes 2017
32155444-22842542-20753393 49710-49714 22842542 denotes 2012
32155444-22842542-20753393 49710-49714 22842542 denotes 2012
32155444-16963278-20753394 49783-49787 16963278 denotes 2007
32155444-16963278-20753394 49783-49787 16963278 denotes 2007
32155444-25615868-20753395 49958-49962 25615868 denotes 2015
32155444-25615868-20753395 49958-49962 25615868 denotes 2015
32155444-20383002-20753396 49979-49983 20383002 denotes 2010
32155444-20383002-20753396 49979-49983 20383002 denotes 2010
32155444-27669148-20753397 50185-50189 27669148 denotes 2016
32155444-27669148-20753397 50185-50189 27669148 denotes 2016
32155444-30344107-20753398 50367-50371 30344107 denotes 2019
32155444-30344107-20753398 50367-50371 30344107 denotes 2019
32155444-20057044-20753399 50486-50490 20057044 denotes 2010
32155444-20057044-20753399 50486-50490 20057044 denotes 2010
32155444-26280328-20753400 50517-50521 26280328 denotes 2015
32155444-26280328-20753400 50517-50521 26280328 denotes 2015
32155444-31588918-20753401 50551-50555 31588918 denotes 2019
32155444-31588918-20753401 50551-50555 31588918 denotes 2019
32155444-26581513-20753402 50587-50591 26581513 denotes 2015
32155444-26581513-20753402 50587-50591 26581513 denotes 2015
32155444-28710774-20753403 50739-50743 28710774 denotes 2018
32155444-28710774-20753403 50739-50743 28710774 denotes 2018
32155444-27166375-20753404 50776-50780 27166375 denotes 2016
32155444-27166375-20753404 50776-50780 27166375 denotes 2016
32155444-30712865-20753405 51118-51122 30712865 denotes 2019
32155444-30712865-20753405 51118-51122 30712865 denotes 2019