PMC:7102591 / 21259-21822 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"640","span":{"begin":424,"end":440},"obj":"Species"},{"id":"641","span":{"begin":0,"end":11},"obj":"Chemical"},{"id":"642","span":{"begin":16,"end":34},"obj":"Chemical"},{"id":"643","span":{"begin":221,"end":232},"obj":"Chemical"},{"id":"644","span":{"begin":155,"end":186},"obj":"Disease"},{"id":"645","span":{"begin":197,"end":199},"obj":"Disease"}],"attributes":[{"id":"A640","pred":"tao:has_database_id","subj":"640","obj":"Tax:694009"},{"id":"A641","pred":"tao:has_database_id","subj":"641","obj":"MESH:D002738"},{"id":"A642","pred":"tao:has_database_id","subj":"642","obj":"MESH:D006886"},{"id":"A643","pred":"tao:has_database_id","subj":"643","obj":"MESH:D002738"},{"id":"A644","pred":"tao:has_database_id","subj":"644","obj":"MESH:D000163"},{"id":"A645","pred":"tao:has_database_id","subj":"645","obj":"MESH:D001172"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Chloroquine and hydroxychloroquine are widely used anti-malarial drugs with well-known immunomodulatory properties that have extended their use to several immuno-rheumatological diseases including RA [83]. The ability of chloroquine to produce an anti-viral effect has been known since the late 1960s [84]. Several mechanisms by which the drug is able to interfere with the growth and spread of different viruses (including SARS coronavirus) have been demonstrated in in vitro studies [85], even though the subsequent in vivo experience was controversial [86,87]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T245","span":{"begin":197,"end":199},"obj":"Disease"},{"id":"T247","span":{"begin":424,"end":428},"obj":"Disease"}],"attributes":[{"id":"A245","pred":"mondo_id","subj":"T245","obj":"http://purl.obolibrary.org/obo/MONDO_0005272"},{"id":"A246","pred":"mondo_id","subj":"T245","obj":"http://purl.obolibrary.org/obo/MONDO_0008383"},{"id":"A247","pred":"mondo_id","subj":"T247","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Chloroquine and hydroxychloroquine are widely used anti-malarial drugs with well-known immunomodulatory properties that have extended their use to several immuno-rheumatological diseases including RA [83]. The ability of chloroquine to produce an anti-viral effect has been known since the late 1960s [84]. Several mechanisms by which the drug is able to interfere with the growth and spread of different viruses (including SARS coronavirus) have been demonstrated in in vitro studies [85], even though the subsequent in vivo experience was controversial [86,87]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T144","span":{"begin":265,"end":268},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T145","span":{"begin":405,"end":412},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"}],"text":"Chloroquine and hydroxychloroquine are widely used anti-malarial drugs with well-known immunomodulatory properties that have extended their use to several immuno-rheumatological diseases including RA [83]. The ability of chloroquine to produce an anti-viral effect has been known since the late 1960s [84]. Several mechanisms by which the drug is able to interfere with the growth and spread of different viruses (including SARS coronavirus) have been demonstrated in in vitro studies [85], even though the subsequent in vivo experience was controversial [86,87]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T171","span":{"begin":0,"end":11},"obj":"Chemical"},{"id":"T172","span":{"begin":16,"end":34},"obj":"Chemical"},{"id":"T173","span":{"begin":65,"end":70},"obj":"Chemical"},{"id":"T174","span":{"begin":197,"end":199},"obj":"Chemical"},{"id":"T175","span":{"begin":221,"end":232},"obj":"Chemical"},{"id":"T176","span":{"begin":339,"end":343},"obj":"Chemical"}],"attributes":[{"id":"A171","pred":"chebi_id","subj":"T171","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"},{"id":"A172","pred":"chebi_id","subj":"T172","obj":"http://purl.obolibrary.org/obo/CHEBI_5801"},{"id":"A173","pred":"chebi_id","subj":"T173","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"},{"id":"A174","pred":"chebi_id","subj":"T174","obj":"http://purl.obolibrary.org/obo/CHEBI_73810"},{"id":"A175","pred":"chebi_id","subj":"T175","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"},{"id":"A176","pred":"chebi_id","subj":"T176","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"}],"text":"Chloroquine and hydroxychloroquine are widely used anti-malarial drugs with well-known immunomodulatory properties that have extended their use to several immuno-rheumatological diseases including RA [83]. The ability of chloroquine to produce an anti-viral effect has been known since the late 1960s [84]. Several mechanisms by which the drug is able to interfere with the growth and spread of different viruses (including SARS coronavirus) have been demonstrated in in vitro studies [85], even though the subsequent in vivo experience was controversial [86,87]."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T40","span":{"begin":374,"end":380},"obj":"http://purl.obolibrary.org/obo/GO_0040007"}],"text":"Chloroquine and hydroxychloroquine are widely used anti-malarial drugs with well-known immunomodulatory properties that have extended their use to several immuno-rheumatological diseases including RA [83]. The ability of chloroquine to produce an anti-viral effect has been known since the late 1960s [84]. Several mechanisms by which the drug is able to interfere with the growth and spread of different viruses (including SARS coronavirus) have been demonstrated in in vitro studies [85], even though the subsequent in vivo experience was controversial [86,87]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T120","span":{"begin":0,"end":205},"obj":"Sentence"},{"id":"T121","span":{"begin":206,"end":306},"obj":"Sentence"},{"id":"T122","span":{"begin":307,"end":563},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Chloroquine and hydroxychloroquine are widely used anti-malarial drugs with well-known immunomodulatory properties that have extended their use to several immuno-rheumatological diseases including RA [83]. The ability of chloroquine to produce an anti-viral effect has been known since the late 1960s [84]. Several mechanisms by which the drug is able to interfere with the growth and spread of different viruses (including SARS coronavirus) have been demonstrated in in vitro studies [85], even though the subsequent in vivo experience was controversial [86,87]."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T72","span":{"begin":197,"end":199},"obj":"Phenotype"}],"attributes":[{"id":"A72","pred":"hp_id","subj":"T72","obj":"http://purl.obolibrary.org/obo/HP_0001370"}],"text":"Chloroquine and hydroxychloroquine are widely used anti-malarial drugs with well-known immunomodulatory properties that have extended their use to several immuno-rheumatological diseases including RA [83]. The ability of chloroquine to produce an anti-viral effect has been known since the late 1960s [84]. Several mechanisms by which the drug is able to interfere with the growth and spread of different viruses (including SARS coronavirus) have been demonstrated in in vitro studies [85], even though the subsequent in vivo experience was controversial [86,87]."}

{"project":"2_test","denotations":[{"id":"32205186-32034323-4826913","span":{"begin":201,"end":203},"obj":"32034323"},{"id":"32205186-4306296-4826914","span":{"begin":302,"end":304},"obj":"4306296"},{"id":"32205186-21550310-4826915","span":{"begin":556,"end":558},"obj":"21550310"}],"text":"Chloroquine and hydroxychloroquine are widely used anti-malarial drugs with well-known immunomodulatory properties that have extended their use to several immuno-rheumatological diseases including RA [83]. The ability of chloroquine to produce an anti-viral effect has been known since the late 1960s [84]. Several mechanisms by which the drug is able to interfere with the growth and spread of different viruses (including SARS coronavirus) have been demonstrated in in vitro studies [85], even though the subsequent in vivo experience was controversial [86,87]."}