PMC:7102591 / 20012-21015
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 595 | 207-212 | Gene | denotes | ACE 2 | Gene:59272 |
| 596 | 235-239 | Gene | denotes | IL-6 | Gene:3569 |
| 597 | 505-508 | Gene | denotes | NAK | Gene:29110 |
| 598 | 835-839 | Gene | denotes | ACE2 | Gene:59272 |
| 599 | 666-669 | Gene | denotes | TNF | Gene:7124 |
| 600 | 344-352 | Species | denotes | patients | Tax:9606 |
| 601 | 301-305 | Disease | denotes | ARDS | MESH:D012128 |
| 602 | 396-405 | Disease | denotes | pneumonia | MESH:D011014 |
| 603 | 618-622 | Disease | denotes | ARDS | MESH:D012128 |
| 604 | 641-665 | Disease | denotes | secondary HZV infections | MESH:D060085 |
| 605 | 750-765 | Disease | denotes | viral infection | MESH:D001102 |
| 606 | 866-871 | Disease | denotes | fever | MESH:D005334 |
| 607 | 916-931 | Disease | denotes | viral infection | MESH:D001102 |
| 608 | 942-951 | Disease | denotes | mortality | MESH:D003643 |
| 609 | 987-1003 | Disease | denotes | fungal infection | MESH:D009181 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T71 | 53-62 | Body_part | denotes | endosomal | http://purl.org/sig/ont/fma/fma67180 |
| T72 | 85-89 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T73 | 264-272 | Body_part | denotes | cytokine | http://purl.org/sig/ont/fma/fma84050 |
| T74 | 488-492 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T75 | 581-589 | Body_part | denotes | cytokine | http://purl.org/sig/ont/fma/fma84050 |
| T76 | 726-730 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T231 | 301-305 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
| T232 | 396-405 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T233 | 618-622 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
| T234 | 655-665 | Disease | denotes | infections | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T235 | 750-765 | Disease | denotes | viral infection | http://purl.obolibrary.org/obo/MONDO_0005108 |
| T236 | 756-765 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T237 | 916-931 | Disease | denotes | viral infection | http://purl.obolibrary.org/obo/MONDO_0005108 |
| T238 | 922-931 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T239 | 987-1003 | Disease | denotes | fungal infection | http://purl.obolibrary.org/obo/MONDO_0002041 |
| T240 | 994-1003 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T138 | 79-84 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T139 | 85-89 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T140 | 131-139 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T141 | 488-492 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T142 | 726-730 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T157 | 10-21 | Chemical | denotes | Chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T158 | 235-237 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T160 | 240-250 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T161 | 670-680 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T162 | 771-777 | Chemical | denotes | NSAIDs | http://purl.obolibrary.org/obo/CHEBI_35475 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T27 | 85-96 | http://purl.obolibrary.org/obo/GO_0140253 | denotes | cell fusion |
| T28 | 85-96 | http://purl.obolibrary.org/obo/GO_0045026 | denotes | cell fusion |
| T29 | 85-96 | http://purl.obolibrary.org/obo/GO_0000768 | denotes | cell fusion |
| T30 | 85-96 | http://purl.obolibrary.org/obo/GO_0000747 | denotes | cell fusion |
| T31 | 122-139 | http://purl.obolibrary.org/obo/GO_0038024 | denotes | receptor activity |
| T32 | 159-181 | http://purl.obolibrary.org/obo/GO_0033578 | denotes | terminal glycosylation |
| T33 | 168-181 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
| T34 | 461-478 | http://purl.obolibrary.org/obo/GO_0046718 | denotes | viral penetration |
| T35 | 518-529 | http://purl.obolibrary.org/obo/GO_0006897 | denotes | endocytosis |
| T36 | 699-716 | http://purl.obolibrary.org/obo/GO_0046718 | denotes | viral penetration |
| T37 | 750-765 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | viral infection |
| T38 | 796-813 | http://purl.obolibrary.org/obo/GO_0046718 | denotes | viral penetration |
| T39 | 916-931 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | viral infection |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T105 | 0-9 | Sentence | denotes | PROS CONS |
| T106 | 10-215 | Sentence | denotes | Chloroquine Anti-viral effect (increase of endosomal pH required for virus/cell fusion, inhibition of toll-like receptor activity, interference with terminal glycosylation of the cellular receptor ACE 2) – |
| T107 | 216-234 | Sentence | denotes | Hydroxychloroquine |
| T108 | 235-366 | Sentence | denotes | IL-6 inhibitors Treatment of cytokine storm manifestations during ARDS Lack of definite criteria to identify patients to be treated |
| T109 | 367-430 | Sentence | denotes | Potential community-acquired pneumonia due to immunosuppression |
| T110 | 431-567 | Sentence | denotes | Baricitinib Interference with viral penetration into the cell by blocking NAK-mediated endocytosis Impairment of IFN anti-viral response |
| T111 | 568-665 | Sentence | denotes | Treatment of cytokine storm manifestations during ARDS Increased risk of secondary HZV infections |
| T112 | 666-770 | Sentence | denotes | TNF-inhibitors Interference with viral penetration into the cell Slight increase in viral infection risk |
| T113 | 771-839 | Sentence | denotes | NSAIDs – Facilitation of viral penetration by overexpression of ACE2 |
| T114 | 840-879 | Sentence | denotes | Delay in diagnosis due to fever masking |
| T115 | 880-931 | Sentence | denotes | Corticosteroids – Increased risk of viral infection |
| T116 | 932-1003 | Sentence | denotes | Increased mortality and risk of secondary bacterial or fungal infection |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T67 | 264-278 | Phenotype | denotes | cytokine storm | http://purl.obolibrary.org/obo/HP_0033041 |
| T68 | 396-405 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
| T69 | 581-595 | Phenotype | denotes | cytokine storm | http://purl.obolibrary.org/obo/HP_0033041 |
| T70 | 866-871 | Phenotype | denotes | fever | http://purl.obolibrary.org/obo/HP_0001945 |