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PMC:7102591 / 19693-21221 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
595 526-531 Gene denotes ACE 2 Gene:59272
596 554-558 Gene denotes IL-6 Gene:3569
597 824-827 Gene denotes NAK Gene:29110
598 1154-1158 Gene denotes ACE2 Gene:59272
599 985-988 Gene denotes TNF Gene:7124
600 663-671 Species denotes patients Tax:9606
601 620-624 Disease denotes ARDS MESH:D012128
602 715-724 Disease denotes pneumonia MESH:D011014
603 937-941 Disease denotes ARDS MESH:D012128
604 960-984 Disease denotes secondary HZV infections MESH:D060085
605 1069-1084 Disease denotes viral infection MESH:D001102
606 1185-1190 Disease denotes fever MESH:D005334
607 1235-1250 Disease denotes viral infection MESH:D001102
608 1261-1270 Disease denotes mortality MESH:D003643
609 1306-1322 Disease denotes fungal infection MESH:D009181
612 299-307 Disease denotes COVID-19 MESH:C000657245
613 308-317 Disease denotes infection MESH:D007239
620 1323-1327 Gene denotes ACE2 Gene:59272
621 1330-1361 Gene denotes angiotensin converting enzyme 2 Gene:59272
622 1407-1410 Gene denotes NAK Gene:29110
623 1413-1435 Gene denotes numb-associated kinase Gene:29110
624 1363-1367 Disease denotes ARDS MESH:D012128
625 1370-1405 Disease denotes acute respiratory distress syndrome MESH:D012128
629 93-95 Disease denotes RA MESH:D001172
630 141-149 Disease denotes COVID-19 MESH:C000657245
631 227-236 Disease denotes infection MESH:D007239

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T71 372-381 Body_part denotes endosomal http://purl.org/sig/ont/fma/fma67180
T72 404-408 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T73 583-591 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T74 807-811 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T75 900-908 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T76 1045-1049 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T225 93-95 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T227 141-149 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T228 227-236 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T229 299-307 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T230 308-317 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T231 620-624 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T232 715-724 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T233 937-941 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T234 974-984 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T235 1069-1084 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T236 1075-1084 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T237 1235-1250 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T238 1241-1250 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T239 1306-1322 Disease denotes fungal infection http://purl.obolibrary.org/obo/MONDO_0002041
T240 1313-1322 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T241 1363-1367 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T242 1370-1405 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T243 1376-1405 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T244 1450-1456 Disease denotes Zoster http://purl.obolibrary.org/obo/MONDO_0005609

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T137 153-154 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T138 398-403 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T139 404-408 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T140 450-458 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T141 807-811 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T142 1045-1049 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T143 1457-1462 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T153 53-58 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T154 93-95 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T155 275-295 Chemical denotes anti-rheumatic drugs http://purl.obolibrary.org/obo/CHEBI_35842
T156 290-295 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T157 329-340 Chemical denotes Chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T158 554-556 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T160 559-569 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T161 989-999 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T162 1090-1096 Chemical denotes NSAIDs http://purl.obolibrary.org/obo/CHEBI_35475
T163 1330-1341 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T164 1470-1480 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T165 1482-1488 Chemical denotes NSAIDs http://purl.obolibrary.org/obo/CHEBI_35475
T166 1491-1527 Chemical denotes nonsteroidal anti-inflammatory drugs http://purl.obolibrary.org/obo/CHEBI_35475
T167 1504-1527 Chemical denotes anti-inflammatory drugs http://purl.obolibrary.org/obo/CHEBI_35472
T168 1522-1527 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T27 404-415 http://purl.obolibrary.org/obo/GO_0140253 denotes cell fusion
T28 404-415 http://purl.obolibrary.org/obo/GO_0045026 denotes cell fusion
T29 404-415 http://purl.obolibrary.org/obo/GO_0000768 denotes cell fusion
T30 404-415 http://purl.obolibrary.org/obo/GO_0000747 denotes cell fusion
T31 441-458 http://purl.obolibrary.org/obo/GO_0038024 denotes receptor activity
T32 478-500 http://purl.obolibrary.org/obo/GO_0033578 denotes terminal glycosylation
T33 487-500 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T34 780-797 http://purl.obolibrary.org/obo/GO_0046718 denotes viral penetration
T35 837-848 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis
T36 1018-1035 http://purl.obolibrary.org/obo/GO_0046718 denotes viral penetration
T37 1069-1084 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T38 1115-1132 http://purl.obolibrary.org/obo/GO_0046718 denotes viral penetration
T39 1235-1250 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T103 0-248 Sentence denotes Beyond the use of specific anti-viral products, many drugs commonly used in the treatment of RA have been proposed as possible therapies for COVID-19 as a consequence of the increased knowledge about the pathophysiology of the infection (Table 1 ).
T104 249-318 Sentence denotes Table 1 Potential role of anti-rheumatic drugs in COVID-19 infection.
T105 319-328 Sentence denotes PROS CONS
T106 329-534 Sentence denotes Chloroquine Anti-viral effect (increase of endosomal pH required for virus/cell fusion, inhibition of toll-like receptor activity, interference with terminal glycosylation of the cellular receptor ACE 2) –
T107 535-553 Sentence denotes Hydroxychloroquine
T108 554-685 Sentence denotes IL-6 inhibitors Treatment of cytokine storm manifestations during ARDS Lack of definite criteria to identify patients to be treated
T109 686-749 Sentence denotes Potential community-acquired pneumonia due to immunosuppression
T110 750-886 Sentence denotes Baricitinib Interference with viral penetration into the cell by blocking NAK-mediated endocytosis Impairment of IFN anti-viral response
T111 887-984 Sentence denotes Treatment of cytokine storm manifestations during ARDS Increased risk of secondary HZV infections
T112 985-1089 Sentence denotes TNF-inhibitors Interference with viral penetration into the cell Slight increase in viral infection risk
T113 1090-1158 Sentence denotes NSAIDs – Facilitation of viral penetration by overexpression of ACE2
T114 1159-1198 Sentence denotes Delay in diagnosis due to fever masking
T115 1199-1250 Sentence denotes Corticosteroids – Increased risk of viral infection
T116 1251-1322 Sentence denotes Increased mortality and risk of secondary bacterial or fungal infection
T117 1323-1463 Sentence denotes ACE2 = angiotensin converting enzyme 2, ARDS = acute respiratory distress syndrome, NAK = numb-associated kinase; HZV = Herpes Zoster virus,
T118 1464-1528 Sentence denotes IFN = interferon, NSAIDs = nonsteroidal anti-inflammatory drugs.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T66 93-95 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T67 583-597 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T68 715-724 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T69 900-914 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T70 1185-1190 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T71 1376-1396 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098