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PMC:7102591 / 17875-19692 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
557 527-537 Species denotes SARS-CoV-2 Tax:2697049
558 548-563 Species denotes Betacoronavirus Tax:694002
559 602-610 Species denotes SARS-CoV Tax:694009
560 615-623 Species denotes MERS-Cov Tax:1335626
561 1496-1507 Species denotes coronavirus Tax:11118
562 1572-1581 Species denotes SARS-CoV2 Tax:2697049
563 1610-1615 Species denotes human Tax:9606
564 1454-1459 Species denotes human Tax:9606
565 706-715 Chemical denotes ribavirin MESH:D012254
566 721-740 Chemical denotes lopinavir-ritonavir MESH:C558899
567 836-855 Chemical denotes lopinavir-ritonavir MESH:C558899
568 938-948 Chemical denotes remdesivir MESH:C000606551
569 953-962 Chemical denotes adenosine MESH:D000241
570 1260-1279 Chemical denotes lopinavir-ritonavir MESH:C558899
571 1284-1294 Chemical denotes remdesevir
572 89-104 Disease denotes CoV-2 infection MESH:C000657245
573 145-153 Disease denotes COVID-19 MESH:C000657245
574 350-358 Disease denotes COVID-19 MESH:C000657245
575 459-475 Disease denotes viral infections MESH:D001102
576 772-780 Disease denotes COVID-19 MESH:C000657245
577 1028-1043 Disease denotes virus infection MESH:D001102
578 1219-1239 Disease denotes SARS-CoV-2 infection MESH:C000657245
579 1392-1400 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T69 1139-1142 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T70 1623-1628 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T210 84-92 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T211 95-104 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T212 145-153 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T213 350-358 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T214 459-475 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T215 527-535 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T216 602-610 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T217 772-780 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T218 1022-1027 Disease denotes Ebola http://purl.obolibrary.org/obo/MONDO_0005737
T219 1028-1043 Disease denotes virus infection http://purl.obolibrary.org/obo/MONDO_0005108
T220 1034-1043 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T221 1219-1227 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T222 1230-1239 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T223 1392-1400 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T224 1572-1576 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T127 186-187 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T128 382-389 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T129 1028-1033 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T130 1050-1053 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T131 1082-1083 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T132 1120-1121 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T133 1143-1150 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T134 1454-1459 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T135 1610-1615 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T136 1623-1628 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T134 419-434 Chemical denotes antiviral drugs http://purl.obolibrary.org/obo/CHEBI_36044
T135 419-428 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T136 429-434 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T137 634-639 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T138 694-704 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T139 706-715 Chemical denotes ribavirin http://purl.obolibrary.org/obo/CHEBI_63580
T140 721-740 Chemical denotes lopinavir-ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T141 721-730 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T142 731-740 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T143 836-855 Chemical denotes lopinavir-ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T144 836-845 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T145 846-855 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T146 938-948 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T147 953-962 Chemical denotes adenosine http://purl.obolibrary.org/obo/CHEBI_16335
T148 1094-1103 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T149 1260-1279 Chemical denotes lopinavir-ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T150 1260-1269 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T151 1270-1279 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T152 1329-1334 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T26 459-475 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T95 0-287 Sentence denotes Currently, vaccines and approved targeted therapeutics for the treatment of the new SARS-CoV-2 infection are still lacking and the management of COVID-19 is only supportive, even though a multitude of compounds are now under investigation for the treatment of this emerging disease [75].
T96 288-476 Sentence denotes The need to urgently identify an effective approach to manage COVID-19 led to the strategy of testing the efficacy of the existing antiviral drugs commonly used for other viral infections.
T97 477-786 Sentence denotes In particular, considering the similarity between SARS-CoV-2 and other Betacoronavirus associated with previous epidemics as SARS-CoV and MERS-Cov, the same drugs used with controversial results for these conditions (interferon, ribavirin, and lopinavir-ritonavir) have been considered even for COVID-19 [76].
T98 787-924 Sentence denotes Anecdotal cases have demonstrated the ability of lopinavir-ritonavir to significantly reduce viral load and improve disease outcome [77].
T99 925-1245 Sentence denotes In addition, remdesivir, an adenosine analogue currently under development for the management of Ebola virus infection [78], has been recently recognized as a promising antiviral therapy against a wide spectrum of RNA viruses [79] and showed good preliminary in vitro results in the control of SARS-CoV-2 infection [80].
T100 1246-1406 Sentence denotes Consequently, lopinavir-ritonavir and remdesevir are currently the only anti-viral drugs included in the more severe case management protocols of COVID-19 [10].
T101 1407-1637 Sentence denotes Recent reports described the potential role of human monoclonal antibodies that bind the coronavirus spike receptor binding domain, leading to the neutralization of SARS-CoV2 capability to interact with human target cells [81,82].
T102 1638-1817 Sentence denotes However, at the moment these can only be considered as potential treatment options for the future, but they are obviously not available for the management of the current pandemic.

2_test

Id Subject Object Predicate Lexical cue
32205186-26868298-4826910 782-784 26868298 denotes 76
32205186-32020029-4826911 1241-1243 32020029 denotes 80
32205186-30938227-4826912 1630-1632 30938227 denotes 81