PMC:7102591 / 13585-14708
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 449 | 991-994 | Gene | denotes | MTX | Gene:4580 |
| 450 | 68-76 | Species | denotes | patients | Tax:9606 |
| 451 | 639-647 | Species | denotes | patients | Tax:9606 |
| 452 | 972-980 | Species | denotes | patients | Tax:9606 |
| 453 | 737-749 | Chemical | denotes | methotrexate | MESH:D008727 |
| 454 | 791-809 | Chemical | denotes | hydroxychloroquine | MESH:D006886 |
| 455 | 160-162 | Disease | denotes | RA | MESH:D001172 |
| 456 | 248-250 | Disease | denotes | RA | MESH:D001172 |
| 457 | 390-399 | Disease | denotes | infection | MESH:D007239 |
| 458 | 527-536 | Disease | denotes | infection | MESH:D007239 |
| 459 | 723-732 | Disease | denotes | infection | MESH:D007239 |
| 460 | 959-968 | Disease | denotes | infection | MESH:D007239 |
| 461 | 1101-1110 | Disease | denotes | infection | MESH:D007239 |
LitCovid_AGAC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| p51595s16 | 694-701 | NegReg | denotes | reduced |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T178 | 49-59 | Disease | denotes | infectious | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T179 | 160-162 | Disease | denotes | RA | http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383 |
| T181 | 248-250 | Disease | denotes | RA | http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383 |
| T183 | 390-399 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T184 | 527-536 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T185 | 710-732 | Disease | denotes | hospitalized infection | http://purl.obolibrary.org/obo/MONDO_0043544 |
| T186 | 723-732 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T187 | 959-968 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T188 | 1101-1110 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T103 | 102-103 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T104 | 141-142 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T105 | 213-214 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T106 | 365-366 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T107 | 653-654 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T108 | 683-684 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T109 | 848-850 | http://purl.obolibrary.org/obo/CLO_0001407 | denotes | 52 |
| T110 | 853-854 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T108 | 160-162 | Chemical | denotes | RA | http://purl.obolibrary.org/obo/CHEBI_73810 |
| T109 | 248-250 | Chemical | denotes | RA | http://purl.obolibrary.org/obo/CHEBI_73810 |
| T110 | 329-344 | Chemical | denotes | corticosteroids | http://purl.obolibrary.org/obo/CHEBI_50858 |
| T111 | 427-429 | Chemical | denotes | RR | http://purl.obolibrary.org/obo/CHEBI_73811 |
| T112 | 552-554 | Chemical | denotes | RR | http://purl.obolibrary.org/obo/CHEBI_73811 |
| T113 | 737-749 | Chemical | denotes | methotrexate | http://purl.obolibrary.org/obo/CHEBI_44185|http://purl.obolibrary.org/obo/CHEBI_50681 |
| T115 | 760-762 | Chemical | denotes | RR | http://purl.obolibrary.org/obo/CHEBI_73811 |
| T116 | 791-809 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
| T117 | 820-822 | Chemical | denotes | RR | http://purl.obolibrary.org/obo/CHEBI_73811 |
| T118 | 991-994 | Chemical | denotes | MTX | http://purl.obolibrary.org/obo/CHEBI_44185 |
| T119 | 996-998 | Chemical | denotes | RR | http://purl.obolibrary.org/obo/CHEBI_73811 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T71 | 0-13 | Sentence | denotes | 4.2 csDMARDs |
| T72 | 14-304 | Sentence | denotes | The most comprehensive analysis of infectious risk in patients treated with csDMARDs is a retrospective, longitudinal study of a population-based RA cohort using an administrative database including a total of 27,710 individuals with RA and providing 162,710 person-years of follow-up [51]. |
| T73 | 305-578 | Sentence | denotes | Use of csDMARDs without corticosteroids was associated with a small decrease in mild infection risk (adjusted rate ratio [RR] 0.90, 95% confidence interval [95% CI] 0.88–0.93) and was not associated with increased serious infection risk (adjusted RR 0.92, 95% CI 0.85–1.0). |
| T74 | 579-852 | Sentence | denotes | Similarly, another retrospective analysis conducted on 1993 patients from a claim database demonstrated a slightly reduced risk of hospitalized infection for methotrexate (adjusted RR 0.81, 95% CI 0.70–0.93) and hydroxychloroquine (adjusted RR 0.74, 95% CI 0.62–0.89) [52]. |
| T75 | 853-999 | Sentence | denotes | A recent systematic review and meta-analysis of the literature confirmed the lack of an increased risk of infection in patients receiving MTX (RR: |
| T76 | 1000-1030 | Sentence | denotes | 1.14; 95% CI, 0.98–1.34) [53]. |
| T77 | 1031-1123 | Sentence | denotes | However, all these reports provided no data on the risk of stratified infection by pathogen. |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T59 | 160-162 | Phenotype | denotes | RA | http://purl.obolibrary.org/obo/HP_0001370 |
| T60 | 248-250 | Phenotype | denotes | RA | http://purl.obolibrary.org/obo/HP_0001370 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32205186-18668604-4826892 | 300-302 | 18668604 | denotes | 51 |
| 32205186-18260176-4826893 | 848-850 | 18260176 | denotes | 52 |