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PMC:7102591 / 1247-31801 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
52 119-129 Species denotes SARS-CoV-2 Tax:2697049
53 156-169 Species denotes coronavirus 2 Tax:2697049
54 325-333 Species denotes SARS-CoV Tax:694009
55 363-373 Species denotes SARS-CoV-2 Tax:2697049
56 540-548 Species denotes patients Tax:9606
57 144-155 Species denotes respiratory Tax:12814
58 47-56 Disease denotes pneumonia MESH:D011014
59 394-403 Disease denotes dry cough MESH:D003371
60 405-410 Disease denotes fever MESH:D005334
61 412-419 Disease denotes dyspnea MESH:D004417
62 424-431 Disease denotes fatigue MESH:D005221
63 448-459 Disease denotes lymphopenia MESH:D008231
64 531-539 Disease denotes infected MESH:D007239
65 619-628 Disease denotes pneumonia MESH:D011014
66 634-649 Disease denotes alveolar damage MESH:D055370
67 687-722 Disease denotes Acute Respiratory Distress Syndrome MESH:D012128
68 724-728 Disease denotes ARDS MESH:D012128
69 739-744 Disease denotes death MESH:D003643
70 911-919 Disease denotes COVID-19 MESH:C000657245
71 1190-1196 Disease denotes deaths MESH:D003643
88 2194-2207 Gene denotes interleukin 6 Gene:3569
89 2209-2213 Gene denotes IL-6 Gene:3569
90 1322-1330 Species denotes patients Tax:9606
91 1521-1529 Species denotes patients Tax:9606
92 2013-2024 Chemical denotes Chloroquine MESH:D002738
93 2029-2047 Chemical denotes hydroxychloroquine MESH:D006886
94 1283-1291 Disease denotes COVID-19 MESH:C000657245
95 1314-1321 Disease denotes fragile MESH:D005600
96 1832-1852 Disease denotes SARS-CoV-2 infection MESH:C000657245
97 1928-1948 Disease denotes rheumatoid arthritis MESH:D001172
98 1950-1952 Disease denotes RA MESH:D001172
99 2003-2011 Disease denotes COVID-19 MESH:C000657245
100 2145-2163 Disease denotes COVID-19 pneumonia MESH:C000657245
101 2345-2356 Disease denotes lung damage MESH:D008171
102 2376-2380 Disease denotes ARDS MESH:D012128
103 2426-2444 Disease denotes SARS-CoV infection MESH:C000657245
108 2541-2549 Species denotes patients Tax:9606
109 2750-2758 Species denotes patients Tax:9606
110 2513-2521 Disease denotes COVID-19 MESH:C000657245
111 2747-2749 Disease denotes RA MESH:D001172
114 2932-2940 Disease denotes COVID-19 MESH:C000657245
115 2941-2950 Disease denotes infection MESH:D007239
139 3232-3263 Gene denotes angiotensin-converting enzyme 2 Gene:59272
140 3265-3269 Gene denotes ACE2 Gene:59272
141 3373-3377 Gene denotes ACE2 Gene:59272
142 3647-3651 Gene denotes ACE2 Gene:59272
143 3706-3720 Gene denotes angiotensin II Gene:183
144 3743-3746 Gene denotes ACE Gene:1636
145 3955-3959 Gene denotes ACE2 Gene:59272
146 4577-4581 Gene denotes ACE2 Gene:59272
147 2951-2964 Species denotes Coronaviruses Tax:11118
148 3329-3338 Species denotes SARS-CoV2 Tax:2697049
149 3111-3119 Disease denotes COVID-19 MESH:C000657245
150 3120-3129 Disease denotes infection MESH:D007239
151 3573-3588 Disease denotes viral infection MESH:D001102
152 3595-3615 Disease denotes SARS-CoV-2 infection MESH:C000657245
153 3920-3931 Disease denotes lung damage MESH:D008171
154 4054-4071 Disease denotes diabetes mellitus MESH:D003920
155 4075-4087 Disease denotes hypertension MESH:D006973
156 4183-4192 Disease denotes infection MESH:D007239
157 4213-4221 Disease denotes COVID-19 MESH:C000657245
158 4549-4569 Disease denotes SARS-CoV-2 infection MESH:C000657245
159 4621-4633 Disease denotes hypertension MESH:D006973
160 4635-4652 Disease denotes diabetes mellitus MESH:D003920
161 4658-4673 Disease denotes cerebral stroke MESH:D020521
188 5688-5702 Gene denotes interleukin-1β Gene:3553
189 5704-5709 Gene denotes IL-1β Gene:3552
190 5712-5716 Gene denotes IL-2 Gene:3558
191 5718-5722 Gene denotes IL-6 Gene:3569
192 5724-5728 Gene denotes IL-7 Gene:3574
193 5730-5734 Gene denotes IL-8 Gene:3576
194 5736-5759 Gene denotes tumor necrosis factor-α Gene:7124
195 5761-5764 Gene denotes TNF Gene:7124
196 5783-5806 Gene denotes CXC-chemokine ligand 10 Gene:3627
197 5808-5814 Gene denotes CXCL10 Gene:3627
198 5820-5841 Gene denotes CC-chemokine ligand 2 Gene:6347
199 5843-5847 Gene denotes CCL2 Gene:6347
200 5524-5532 Species denotes patients Tax:9606
201 4931-4935 Disease denotes ARDS MESH:D012128
202 5100-5145 Disease denotes secondary haemophagocytic lymphohistiocytosis MESH:D060085
203 5194-5220 Disease denotes hyperinflammatory syndrome MESH:D061325
204 5258-5299 Disease denotes hypercytokinaemia with multiorgan failure MESH:D009102
205 5328-5344 Disease denotes viral infections MESH:D001102
206 5405-5410 Disease denotes fever MESH:D005334
207 5412-5445 Disease denotes hyperferritinaemia and cytopenias MESH:D006402
208 5451-5472 Disease denotes pulmonary involvement MESH:D008171
209 5484-5488 Disease denotes ARDS MESH:D012128
210 5607-5615 Disease denotes COVID-19 MESH:C000657245
211 5616-5626 Disease denotes infections MESH:D007239
212 5939-5947 Disease denotes COVID-19 MESH:C000657245
213 5948-5957 Disease denotes infection MESH:D007239
217 6010-6018 Species denotes patients Tax:9606
218 5978-5993 Disease denotes viral infection MESH:D001102
219 6007-6009 Disease denotes RA MESH:D001172
252 6610-6621 Species denotes coronavirus Tax:11118
253 6692-6700 Species denotes patients Tax:9606
254 6850-6858 Species denotes patients Tax:9606
255 7028-7036 Species denotes patients Tax:9606
256 7072-7080 Species denotes patients Tax:9606
257 7270-7278 Species denotes patients Tax:9606
258 7659-7667 Species denotes patients Tax:9606
259 7908-7918 Species denotes outpatient Tax:9606
260 8084-8092 Species denotes patients Tax:9606
261 6490-6501 Species denotes respiratory Tax:12814
262 6045-6047 Disease denotes RA MESH:D001172
263 6052-6071 Disease denotes infectious diseases MESH:D003141
264 6243-6252 Disease denotes arthritis MESH:D001168
265 6402-6411 Disease denotes infection MESH:D007239
266 6502-6518 Disease denotes viral infections MESH:D001102
267 6542-6544 Disease denotes RA MESH:D001172
268 6667-6669 Disease denotes RA MESH:D001172
269 6725-6734 Disease denotes arthritis MESH:D001168
270 6736-6746 Disease denotes infections MESH:D007239
271 6847-6849 Disease denotes RA MESH:D001172
272 6896-6905 Disease denotes infection MESH:D007239
273 7053-7055 Disease denotes RA MESH:D001172
274 7069-7071 Disease denotes RA MESH:D001172
275 7197-7207 Disease denotes infections MESH:D007239
276 7284-7310 Disease denotes inflammatory polyarthritis MESH:D001168
277 7366-7375 Disease denotes infection MESH:D007239
278 7508-7528 Disease denotes autoimmune disorders MESH:D001327
279 7656-7658 Disease denotes RA MESH:D001172
280 7802-7812 Disease denotes infections MESH:D007239
281 7919-7929 Disease denotes infections MESH:D007239
282 8044-8054 Disease denotes infections MESH:D007239
283 8337-8361 Disease denotes infectious complications MESH:D011251
293 8493-8495 Disease denotes RA MESH:D001172
294 8502-8519 Disease denotes Diabetes mellitus MESH:D003920
295 8521-8544 Disease denotes cardiovascular diseases MESH:D002318
296 8546-8559 Disease denotes renal failure MESH:D051437
297 8561-8586 Disease denotes interstitial lung disease MESH:D017563
298 8592-8629 Disease denotes chronic obstructive pulmonary disease MESH:D029424
299 8631-8635 Disease denotes COPD MESH:D029424
300 8709-8719 Disease denotes infections MESH:D007239
301 8723-8725 Disease denotes RA MESH:D001172
304 8744-8746 Disease denotes RA MESH:D001172
305 8774-8784 Disease denotes infections MESH:D007239
308 8932-8950 Disease denotes rheumatic diseases MESH:D012216
309 8954-8970 Disease denotes viral infections MESH:D001102
333 9823-9825 Gene denotes CS Gene:1431
334 10198-10200 Gene denotes CS Gene:1431
335 9964-9966 Gene denotes CS Gene:1431
336 9642-9644 Gene denotes CS Gene:1431
337 9313-9315 Gene denotes CS Gene:1431
338 9079-9081 Gene denotes CS Gene:1431
339 9687-9695 Species denotes patients Tax:9606
340 9801-9809 Species denotes patients Tax:9606
341 9945-9953 Species denotes patients Tax:9606
342 10181-10188 Species denotes patient Tax:9606
343 9099-9101 Disease denotes RA MESH:D001172
344 9282-9284 Disease denotes RA MESH:D001172
345 9348-9360 Disease denotes inflammation MESH:D007249
346 9368-9370 Disease denotes RA MESH:D001172
347 9494-9504 Disease denotes infections MESH:D007239
348 9582-9591 Disease denotes infection MESH:D007239
349 9670-9680 Disease denotes infections MESH:D007239
350 9684-9686 Disease denotes RA MESH:D001172
351 9784-9794 Disease denotes infections MESH:D007239
352 9798-9800 Disease denotes RA MESH:D001172
353 9942-9944 Disease denotes RA MESH:D001172
354 10009-10025 Disease denotes viral infections MESH:D001102
355 10117-10134 Disease denotes Zoster infections MESH:D006562
371 10856-10858 Gene denotes CS Gene:1431
372 10232-10234 Gene denotes CS Gene:1431
373 10581-10583 Gene denotes CS Gene:1431
374 10640-10649 Species denotes MERS)-CoV Tax:1335626
375 10659-10667 Species denotes SARS-CoV Tax:694009
376 10435-10446 Species denotes respiratory Tax:12814
377 11007-11016 Species denotes influenza Tax:11309
378 10411-10427 Disease denotes viral infections MESH:D001102
379 10482-10493 Disease denotes lung damage MESH:D008171
380 10512-10516 Disease denotes ARDS MESH:D012128
381 10606-10638 Disease denotes Middle East respiratory syndrome MESH:D018352
382 10721-10738 Disease denotes lung inflammation MESH:D011014
383 10751-10766 Disease denotes alveolar damage MESH:D055370
384 10893-10902 Disease denotes infection MESH:D007239
385 11036-11045 Disease denotes mortality MESH:D003643
399 11588-11590 Gene denotes CS Gene:1431
400 11303-11305 Gene denotes CS Gene:1431
401 11774-11776 Gene denotes CS Gene:1431
402 11471-11473 Gene denotes CS Gene:1431
403 11284-11292 Species denotes patients Tax:9606
404 11404-11412 Species denotes patients Tax:9606
405 11537-11545 Species denotes patients Tax:9606
406 11125-11154 Disease denotes bacterial or fungal infection MESH:D001424
407 11356-11360 Disease denotes ARDS MESH:D012128
408 11551-11559 Disease denotes COVID-19 MESH:C000657245
409 11560-11569 Disease denotes infection MESH:D007239
410 11728-11736 Disease denotes COVID-19 MESH:C000657245
411 11737-11746 Disease denotes infection MESH:D007239
424 11959-11963 Gene denotes ACE2 Gene:302668
425 11986-11990 Species denotes rats Tax:10116
426 12124-12132 Species denotes patients Tax:9606
427 11896-11905 Chemical denotes Ibuprofen MESH:D007052
428 12179-12192 Chemical denotes acetaminophen MESH:D000082
429 11855-11871 Disease denotes viral infections MESH:D001102
430 11977-11985 Disease denotes diabetic MESH:D003920
431 12094-12102 Disease denotes COVID-19 MESH:C000657245
432 12103-12112 Disease denotes infection MESH:D007239
433 12235-12245 Disease denotes fever rise MESH:D005334
434 12253-12261 Disease denotes COVID-19 MESH:C000657245
435 12326-12335 Disease denotes infection MESH:D007239
449 13329-13332 Gene denotes MTX Gene:4580
450 12406-12414 Species denotes patients Tax:9606
451 12977-12985 Species denotes patients Tax:9606
452 13310-13318 Species denotes patients Tax:9606
453 13075-13087 Chemical denotes methotrexate MESH:D008727
454 13129-13147 Chemical denotes hydroxychloroquine MESH:D006886
455 12498-12500 Disease denotes RA MESH:D001172
456 12586-12588 Disease denotes RA MESH:D001172
457 12728-12737 Disease denotes infection MESH:D007239
458 12865-12874 Disease denotes infection MESH:D007239
459 13061-13070 Disease denotes infection MESH:D007239
460 13297-13306 Disease denotes infection MESH:D007239
461 13439-13448 Disease denotes infection MESH:D007239
463 13468-13475 Chemical denotes bDMARDs
469 13513-13521 Species denotes patients Tax:9606
470 13535-13542 Chemical denotes bDMARDs
471 13861-13868 Chemical denotes bDMARDs
472 13488-13497 Disease denotes infection MESH:D007239
473 13510-13512 Disease denotes RA MESH:D001172
483 14543-14546 Gene denotes TNF Gene:7124
484 14227-14235 Species denotes patients Tax:9606
485 14555-14563 Species denotes patients Tax:9606
486 14165-14174 Species denotes influenza Tax:11309
487 14268-14277 Species denotes influenza Tax:11309
488 14613-14622 Species denotes influenza Tax:11309
489 14084-14106 Disease denotes respiratory infections MESH:D012141
490 14180-14190 Disease denotes infections MESH:D007239
491 14667-14672 Disease denotes death MESH:D003643
493 14727-14735 Disease denotes tsDMARDs
512 16003-16008 Gene denotes JAK-1 Gene:3716
513 14843-14851 Species denotes patients Tax:9606
514 15148-15155 Species denotes patient Tax:9606
515 15257-15265 Species denotes patients Tax:9606
516 15424-15431 Species denotes patient Tax:9606
517 15548-15556 Species denotes patients Tax:9606
518 14926-14937 Chemical denotes tofacitinib MESH:C479163
519 14942-14953 Chemical denotes baricitinib MESH:C000596027
520 15057-15068 Chemical denotes tofacitinib MESH:C479163
521 15371-15382 Chemical denotes baricitinib MESH:C000596027
522 15567-15578 Chemical denotes tofacitinib MESH:C479163
523 15772-15782 Chemical denotes prednisone MESH:D011241
524 16030-16042 Chemical denotes upadacitinib MESH:C000613732
525 16047-16057 Chemical denotes filgotinib MESH:C584571
526 14768-14792 Disease denotes opportunistic infections MESH:D009894
527 14840-14842 Disease denotes RA MESH:D001172
528 15030-15040 Disease denotes infections MESH:D007239
529 15254-15256 Disease denotes RA MESH:D001172
531 16507-16535 Disease denotes respiratory virus infections
533 16585-16593 Disease denotes COVID-19 MESH:C000657245
557 17155-17165 Species denotes SARS-CoV-2 Tax:2697049
558 17176-17191 Species denotes Betacoronavirus Tax:694002
559 17230-17238 Species denotes SARS-CoV Tax:694009
560 17243-17251 Species denotes MERS-Cov Tax:1335626
561 18124-18135 Species denotes coronavirus Tax:11118
562 18200-18209 Species denotes SARS-CoV2 Tax:2697049
563 18238-18243 Species denotes human Tax:9606
564 18082-18087 Species denotes human Tax:9606
565 17334-17343 Chemical denotes ribavirin MESH:D012254
566 17349-17368 Chemical denotes lopinavir-ritonavir MESH:C558899
567 17464-17483 Chemical denotes lopinavir-ritonavir MESH:C558899
568 17566-17576 Chemical denotes remdesivir MESH:C000606551
569 17581-17590 Chemical denotes adenosine MESH:D000241
570 17888-17907 Chemical denotes lopinavir-ritonavir MESH:C558899
571 17912-17922 Chemical denotes remdesevir
572 16717-16732 Disease denotes CoV-2 infection MESH:C000657245
573 16773-16781 Disease denotes COVID-19 MESH:C000657245
574 16978-16986 Disease denotes COVID-19 MESH:C000657245
575 17087-17103 Disease denotes viral infections MESH:D001102
576 17400-17408 Disease denotes COVID-19 MESH:C000657245
577 17656-17671 Disease denotes virus infection MESH:D001102
578 17847-17867 Disease denotes SARS-CoV-2 infection MESH:C000657245
579 18020-18028 Disease denotes COVID-19 MESH:C000657245
595 18972-18977 Gene denotes ACE 2 Gene:59272
596 19000-19004 Gene denotes IL-6 Gene:3569
597 19270-19273 Gene denotes NAK Gene:29110
598 19600-19604 Gene denotes ACE2 Gene:59272
599 19431-19434 Gene denotes TNF Gene:7124
600 19109-19117 Species denotes patients Tax:9606
601 19066-19070 Disease denotes ARDS MESH:D012128
602 19161-19170 Disease denotes pneumonia MESH:D011014
603 19383-19387 Disease denotes ARDS MESH:D012128
604 19406-19430 Disease denotes secondary HZV infections MESH:D060085
605 19515-19530 Disease denotes viral infection MESH:D001102
606 19631-19636 Disease denotes fever MESH:D005334
607 19681-19696 Disease denotes viral infection MESH:D001102
608 19707-19716 Disease denotes mortality MESH:D003643
609 19752-19768 Disease denotes fungal infection MESH:D009181
612 18745-18753 Disease denotes COVID-19 MESH:C000657245
613 18754-18763 Disease denotes infection MESH:D007239
620 19769-19773 Gene denotes ACE2 Gene:59272
621 19776-19807 Gene denotes angiotensin converting enzyme 2 Gene:59272
622 19853-19856 Gene denotes NAK Gene:29110
623 19859-19881 Gene denotes numb-associated kinase Gene:29110
624 19809-19813 Disease denotes ARDS MESH:D012128
625 19816-19851 Disease denotes acute respiratory distress syndrome MESH:D012128
629 18539-18541 Disease denotes RA MESH:D001172
630 18587-18595 Disease denotes COVID-19 MESH:C000657245
631 18673-18682 Disease denotes infection MESH:D007239
633 19981-20011 Chemical denotes Chloroquine/hydroxychloroquine
640 20436-20452 Species denotes SARS coronavirus Tax:694009
641 20012-20023 Chemical denotes Chloroquine MESH:D002738
642 20028-20046 Chemical denotes hydroxychloroquine MESH:D006886
643 20233-20244 Chemical denotes chloroquine MESH:D002738
644 20167-20198 Disease denotes immuno-rheumatological diseases MESH:D000163
645 20209-20211 Disease denotes RA MESH:D001172
657 20811-20816 Gene denotes ACE 2 Gene:59272
658 21314-21322 Species denotes patients Tax:9606
659 20616-20627 Chemical denotes chloroquine MESH:D002738
660 21035-21046 Chemical denotes chloroquine MESH:D002738
661 21346-21357 Chemical denotes chloroquine MESH:D002738
662 21599-21617 Chemical denotes hydroxychloroquine MESH:D006886
663 21671-21682 Chemical denotes chloroquine MESH:D002738
664 20997-21015 Disease denotes SARS CoV infection MESH:C000657245
665 21186-21194 Disease denotes COVID-19 MESH:C000657245
666 21462-21471 Disease denotes pneumonia MESH:D011014
667 21908-21928 Disease denotes SARS-CoV-2 infection MESH:C000657245
670 21941-21945 Gene denotes IL-6 Gene:3569
671 21950-21954 Gene denotes IL-1 Gene:3552
703 22585-22589 Gene denotes IL-6 Gene:3569
704 22594-22598 Gene denotes IL-1 Gene:3552
705 22796-22800 Gene denotes IL-1 Gene:3552
706 23112-23115 Gene denotes CRP Gene:1401
707 23384-23388 Gene denotes IL-6 Gene:3569
708 23695-23699 Gene denotes IL-6 Gene:3569
709 22727-22736 Species denotes SARS-CoV2 Tax:2697049
710 22870-22878 Species denotes patients Tax:9606
711 22976-22984 Species denotes patients Tax:9606
712 23160-23168 Species denotes patients Tax:9606
713 23338-23346 Species denotes patients Tax:9606
714 23518-23526 Species denotes patients Tax:9606
715 23031-23042 Chemical denotes tocilizumab MESH:C502936
716 23078-23084 Chemical denotes oxygen MESH:D010100
717 23196-23207 Chemical denotes tocilizumab MESH:C502936
718 23710-23719 Chemical denotes sarilumab MESH:C000592401
719 21986-21990 Disease denotes ARDS MESH:D012128
720 22024-22032 Disease denotes COVID-19 MESH:C000657245
721 22033-22042 Disease denotes infection MESH:D007239
722 22159-22170 Disease denotes lung injury MESH:D055370
723 22426-22442 Disease denotes viral infections MESH:D001102
724 22565-22573 Disease denotes COVID-19 MESH:C000657245
725 22758-22767 Disease denotes pneumonia MESH:D011014
726 22824-22830 Disease denotes sepsis MESH:D018805
727 23004-23012 Disease denotes COVID-19 MESH:C000657245
728 23249-23251 Disease denotes RA MESH:D001172
729 23352-23370 Disease denotes COVID-19 pneumonia MESH:C000657245
730 23532-23541 Disease denotes pneumonia MESH:D011014
731 23552-23571 Disease denotes respiratory failure MESH:D012131
732 23586-23595 Disease denotes mortality MESH:D003643
733 23626-23636 Disease denotes TOCIVID-19 MESH:C000657245
746 24021-24024 Gene denotes CD4 Gene:920
747 24029-24032 Gene denotes CD8 Gene:925
748 24113-24117 Gene denotes IL-6 Gene:3569
749 23935-23943 Species denotes patients Tax:9606
750 24258-24266 Species denotes patients Tax:9606
751 24453-24461 Species denotes patients Tax:9606
752 23858-23866 Disease denotes COVID-19 MESH:C000657245
753 23867-23876 Disease denotes infection MESH:D007239
754 23977-23988 Disease denotes lung injury MESH:D055370
755 24229-24249 Disease denotes critically pneumonia MESH:D016638
756 24267-24275 Disease denotes infected MESH:D007239
757 24281-24289 Disease denotes COVID-19 MESH:C000657245
759 24512-24515 Gene denotes TNF Gene:7124
764 24610-24614 Gene denotes ACE2 Gene:59272
765 24668-24673 Gene denotes renin Gene:5972
766 24552-24570 Disease denotes SARS-CoV infection MESH:C000657245
767 24709-24720 Disease denotes lung injury MESH:D055370
778 24781-24804 Gene denotes TNF-α-converting enzyme Gene:6868
779 24806-24810 Gene denotes TACE Gene:6868
780 24838-24842 Gene denotes ACE2 Gene:59272
781 24967-24971 Gene denotes TNFα Gene:7124
782 25023-25026 Gene denotes TNF Gene:7124
783 25072-25081 Species denotes SARS-CoV2 Tax:2697049
784 25163-25173 Chemical denotes adalimumab MESH:D000068879
785 25082-25091 Disease denotes infection MESH:D007239
786 25177-25185 Disease denotes COVID-19 MESH:C000657245
787 25186-25195 Disease denotes infection MESH:D007239
829 25512-25534 Gene denotes numb-associated kinase Gene:29110
830 25536-25539 Gene denotes NAK Gene:29110
831 25557-25588 Gene denotes AP2-associated protein kinase 1 Gene:22848
832 25590-25594 Gene denotes AAK1 Gene:22848
833 25600-25626 Gene denotes cyclin G-associated kinase Gene:2580
834 25628-25631 Gene denotes GAK Gene:2580
835 25654-25658 Gene denotes AAK1 Gene:22848
836 25776-25780 Gene denotes AAK1 Gene:22848
837 25826-25830 Gene denotes AAK1 Gene:22848
838 26137-26140 Gene denotes NAK Gene:29110
839 26365-26369 Gene denotes AAK1 Gene:22848
840 26374-26377 Gene denotes GAK Gene:2580
841 26527-26538 Gene denotes JAK 1 and 2 Gene:3716
842 26651-26655 Gene denotes IL-6 Gene:3569
843 27072-27076 Gene denotes AAK1 Gene:22848
844 26660-26676 Gene denotes interferon gamma Gene:3458
845 25349-25359 Species denotes SARS-CoV-2 Tax:2697049
846 26007-26019 Species denotes Dengue virus Tax:12637
847 26021-26032 Species denotes Ebola virus Tax:205488
848 26038-26065 Species denotes respiratory syncytial virus Tax:12814
849 26273-26280 Species denotes patient Tax:9606
850 25890-25899 Chemical denotes erlotinib MESH:D000069347
851 25901-25910 Chemical denotes sunitinib MESH:D000077210
852 25912-25923 Chemical denotes ruxolitinib MESH:C540383
853 25929-25939 Chemical denotes fedratinib MESH:C528327
854 26322-26333 Chemical denotes baricitinib MESH:C000596027
855 26540-26551 Chemical denotes baricitinib MESH:C000596027
856 26805-26816 Chemical denotes baricitinib MESH:C000596027
857 26969-26988 Chemical denotes lopinavir/ritonavir MESH:C558899
858 26993-27003 Chemical denotes remdesivir MESH:C000606551
859 27026-27037 Chemical denotes tofacitinib MESH:C479163
860 27206-27218 Chemical denotes upadacitinib MESH:C000613732
861 27222-27232 Chemical denotes filgotinib MESH:C584571
862 27438-27449 Chemical denotes ruxolitinib MESH:C540383
863 25985-25994 Disease denotes infection MESH:D007239
864 26461-26463 Disease denotes RA MESH:D001172
865 26732-26741 Disease denotes pneumonia MESH:D011014
866 26749-26757 Disease denotes COVID-19 MESH:C000657245
867 27194-27196 Disease denotes RA MESH:D001172
868 27249-27270 Disease denotes coronavirus infection MESH:D018352
869 27403-27411 Disease denotes COVID-19 MESH:C000657245
876 28427-28436 Species denotes SARS-CoV2 Tax:2697049
877 28095-28104 Species denotes Influenza Tax:11309
878 28286-28297 Chemical denotes baricitinib MESH:C000596027
879 27599-27608 Disease denotes infection MESH:D007239
880 27810-27818 Disease denotes infected MESH:D007239
881 28437-28446 Disease denotes infection MESH:D007239
886 28535-28546 Chemical denotes baricitinib MESH:C000596027
887 28567-28575 Disease denotes COVID-19 MESH:C000657245
888 28576-28585 Disease denotes infection MESH:D007239
889 28728-28743 Disease denotes viral pneumonia
904 29624-29626 Gene denotes CS Gene:1431
905 29254-29262 Species denotes patients Tax:9606
906 29457-29464 Species denotes patient Tax:9606
907 29757-29766 Species denotes SARS-CoV2 Tax:2697049
908 28765-28773 Disease denotes COVID-19 MESH:C000657245
909 28886-28888 Disease denotes RA MESH:D001172
910 28913-28945 Disease denotes autoimmune inflammatory disorder MESH:D001327
911 28947-28949 Disease denotes RA MESH:D001172
912 29146-29156 Disease denotes infections MESH:D007239
913 29182-29184 Disease denotes RA MESH:D001172
914 29251-29253 Disease denotes RA MESH:D001172
915 29324-29332 Disease denotes COVID-19 MESH:C000657245
916 29687-29702 Disease denotes viral infection MESH:D001102
917 29780-29789 Disease denotes pneumonia MESH:D011014
933 30040-30044 Gene denotes IL-6 Gene:3569
934 29987-29995 Species denotes patients Tax:9606
935 30254-30262 Species denotes patients Tax:9606
936 30379-30388 Species denotes SARS-CoV2 Tax:2697049
937 29791-29802 Chemical denotes Chloroquine MESH:D002738
938 29807-29825 Chemical denotes hydroxychloroquine MESH:D006886
939 30059-30070 Chemical denotes tocilizumab MESH:C502936
940 30074-30083 Chemical denotes sarilumab MESH:C000592401
941 30339-30350 Chemical denotes baricitinib MESH:C000596027
942 29897-29905 Disease denotes COVID-19 MESH:C000657245
943 29906-29916 Disease denotes infections MESH:D007239
944 29974-29983 Disease denotes infection MESH:D007239
945 30001-30003 Disease denotes RA MESH:D001172
946 30164-30173 Disease denotes pneumonia MESH:D011014
947 30538-30553 Disease denotes viral infection MESH:D001102

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T2 300-310 Body_part denotes nucleotide http://purl.org/sig/ont/fma/fma82740
T3 634-642 Body_part denotes alveolar http://purl.org/sig/ont/fma/fma264783
T4 1412-1416 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T5 1778-1782 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T6 2194-2207 Body_part denotes interleukin 6 http://purl.org/sig/ont/fma/fma264829
T7 2194-2205 Body_part denotes interleukin http://purl.org/sig/ont/fma/fma86578
T8 2285-2293 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T9 2345-2349 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T10 3027-3030 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T11 3031-3037 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T12 3303-3315 Body_part denotes cell-surface http://purl.org/sig/ont/fma/fma67653
T13 3303-3307 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T14 3354-3366 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T15 3399-3406 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T16 3420-3425 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T17 3433-3439 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T18 3441-3446 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T19 3448-3470 Body_part denotes gastrointestinal tract http://purl.org/sig/ont/fma/fma71132
T20 3472-3485 Body_part denotes blood vessels http://purl.org/sig/ont/fma/fma63183
T21 3472-3477 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T22 3505-3509 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T23 3514-3539 Body_part denotes alveolar epithelial cells http://purl.org/sig/ont/fma/fma62499
T24 3534-3539 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T25 3920-3924 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T26 4723-4726 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T27 4727-4733 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T28 4755-4764 Body_part denotes cytoplasm http://purl.org/sig/ont/fma/fma66835
T29 4774-4777 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T30 4903-4909 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T31 4992-5001 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T32 5006-5016 Body_part denotes chemokines http://purl.org/sig/ont/fma/fma241981
T33 5027-5036 Body_part denotes Cytokines http://purl.org/sig/ont/fma/fma84050
T34 5541-5549 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T35 5677-5686 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T36 5688-5701 Body_part denotes interleukin-1 http://purl.org/sig/ont/fma/fma86583
T37 5704-5708 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T38 5712-5716 Body_part denotes IL-2 http://purl.org/sig/ont/fma/fma84051
T39 5771-5781 Body_part denotes chemokines http://purl.org/sig/ont/fma/fma241981
T40 5783-5796 Body_part denotes CXC-chemokine http://purl.org/sig/ont/fma/fma241985
T41 5787-5796 Body_part denotes chemokine http://purl.org/sig/ont/fma/fma241981
T42 5820-5832 Body_part denotes CC-chemokine http://purl.org/sig/ont/fma/fma241983
T43 5882-5890 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T44 6151-6155 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T45 6306-6312 Body_part denotes joints http://purl.org/sig/ont/fma/fma73023
T46 6841-6845 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T47 7479-7492 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T48 8574-8578 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T49 9079-9081 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T50 9313-9315 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T51 9642-9644 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T52 9823-9825 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T53 9964-9966 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T54 10198-10200 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T55 10232-10234 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T56 10246-10250 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T57 10339-10343 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T58 10435-10452 Body_part denotes respiratory tract http://purl.org/sig/ont/fma/fma265130
T59 10482-10486 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T60 10581-10583 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T61 10721-10725 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T62 10751-10759 Body_part denotes alveolar http://purl.org/sig/ont/fma/fma264783
T63 10856-10858 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T64 11303-11305 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T65 11471-11473 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T66 11588-11590 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T67 11774-11776 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T68 16334-16338 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T69 17767-17770 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T70 18251-18256 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T71 18818-18827 Body_part denotes endosomal http://purl.org/sig/ont/fma/fma67180
T72 18850-18854 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T73 19029-19037 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T74 19253-19257 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T75 19346-19354 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T76 19491-19495 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T77 20652-20661 Body_part denotes endosomal http://purl.org/sig/ont/fma/fma67180
T78 20684-20688 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T79 21408-21412 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T80 21950-21954 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T81 22159-22163 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T82 22243-22252 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T83 22312-22323 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863
T84 22348-22353 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T85 22472-22489 Body_part denotes cytotoxic T cells http://purl.org/sig/ont/fma/fma70573
T86 22484-22489 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T87 22594-22598 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T88 22796-22800 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T89 23127-23138 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863
T90 23256-23264 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T91 23977-23981 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T92 24033-24046 Body_part denotes T-lymphocytes http://purl.org/sig/ont/fma/fma62870
T93 24132-24137 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T94 24326-24337 Body_part denotes erythrocyte http://purl.org/sig/ont/fma/fma62845
T95 24371-24379 Body_part denotes platelet http://purl.org/sig/ont/fma/fma62851
T96 24709-24713 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T97 24753-24760 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T98 24905-24909 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T99 25111-25116 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T100 25376-25381 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T101 25463-25471 Body_part denotes clathrin http://purl.org/sig/ont/fma/fma62262
T102 25572-25579 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T103 25697-25701 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T104 25702-25707 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T105 25998-26003 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T106 26385-26391 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T107 27343-27351 Body_part denotes clathrin http://purl.org/sig/ont/fma/fma62262
T108 27819-27824 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T109 29624-29626 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T110 30416-30432 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T111 30427-30432 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T2 1412-1416 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T3 1778-1782 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T4 2345-2349 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T5 3433-3439 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T6 3441-3446 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T7 3472-3485 Body_part denotes blood vessels http://purl.obolibrary.org/obo/UBERON_0001981
T8 3472-3477 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T9 3478-3485 Body_part denotes vessels http://purl.obolibrary.org/obo/UBERON_0000055
T10 3505-3509 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T11 3920-3924 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T12 6151-6155 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T13 6841-6845 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T14 7479-7492 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T15 8574-8578 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T16 10246-10250 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T17 10339-10343 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T18 10435-10452 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T19 10482-10486 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T20 10721-10725 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T21 21408-21412 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T22 22159-22163 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T23 23977-23981 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T24 24132-24137 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T25 24668-24692 Body_part denotes renin-angiotensin system http://purl.obolibrary.org/obo/UBERON_0018229
T26 24709-24713 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T27 25111-25116 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T28 25697-25701 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid_AGAC

Id Subject Object Predicate Lexical cue
p51540s9 3629-3643 NegReg denotes downregulation
p51540s11 3647-3651 Protein denotes ACE2
p51540s12 3652-3662 MPA denotes expression
p51540s17 3682-3691 PosReg denotes excessive
p51540s18 3692-3702 MPA denotes production
p51540s21 3718-3720 MPA denotes II
p51542s9 3864-3876 MPA denotes permeability
p51590s23 12032-12040 PosReg denotes increase
p51595s16 13032-13039 NegReg denotes reduced
p51644s32 20763-20785 MPA denotes terminal glycosylation
p51645s8 20891-20908 MPA denotes -receptor binding
p51651s48 22180-22190 CPA denotes to multior
p51653s23 22522-22531 NegReg denotes decreased
p51653s25 22538-22547 CPA denotes clearance
p51664s14 24590-24604 NegReg denotes a downregulati
p51664s17 24610-24620 MPA denotes ACE2 expre
p51664s21 24639-24648 PosReg denotes an increa
p51664s22 24642-24650 MPA denotes increase
p51685s7 28123-28141 Pathway denotes JAK/STAT signaling
p51685s12 28145-28153 NegReg denotes reducing
p51685s14 28158-28168 MPA denotes expression
p51685s22 28205-28215 NegReg denotes inhibiting
p51685s23 28216-28229 Pathway denotes IFN signaling
p51686s18 28338-28366 MPA denotes mediated anti-viral response
p51695s23 29666-29674 PosReg denotes increase

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T23 47-56 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T24 119-127 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T25 325-333 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T26 363-371 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T27 448-459 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T28 619-628 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T29 687-722 Disease denotes Acute Respiratory Distress Syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T30 693-722 Disease denotes Respiratory Distress Syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T31 724-728 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T32 911-919 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T33 1283-1291 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T34 1585-1595 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T35 1832-1840 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T36 1843-1852 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T37 1928-1948 Disease denotes rheumatoid arthritis http://purl.obolibrary.org/obo/MONDO_0008383
T38 1939-1948 Disease denotes arthritis http://purl.obolibrary.org/obo/MONDO_0005578
T39 1950-1952 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T41 2003-2011 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T42 2145-2153 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T43 2154-2163 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T44 2376-2380 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T45 2426-2444 Disease denotes SARS-CoV infection http://purl.obolibrary.org/obo/MONDO_0005091
T46 2435-2444 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T47 2513-2521 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T48 2728-2738 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T49 2747-2749 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T51 2932-2940 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T52 2941-2950 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T53 3111-3119 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T54 3120-3129 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T55 3329-3333 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T56 3573-3588 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T57 3579-3588 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T58 3595-3603 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T59 3606-3615 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T60 4054-4071 Disease denotes diabetes mellitus http://purl.obolibrary.org/obo/MONDO_0005015
T61 4075-4087 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T62 4183-4192 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T63 4213-4221 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T64 4549-4557 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T65 4560-4569 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T66 4621-4633 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T67 4635-4652 Disease denotes diabetes mellitus http://purl.obolibrary.org/obo/MONDO_0005015
T68 4667-4673 Disease denotes stroke http://purl.obolibrary.org/obo/MONDO_0005098|http://purl.obolibrary.org/obo/MONDO_0011057
T70 4931-4935 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T71 5055-5058 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T73 5100-5145 Disease denotes secondary haemophagocytic lymphohistiocytosis http://purl.obolibrary.org/obo/MONDO_0015542
T74 5147-5151 Disease denotes sHLH http://purl.obolibrary.org/obo/MONDO_0015542
T75 5165-5169 Disease denotes sHLH http://purl.obolibrary.org/obo/MONDO_0015542
T76 5281-5299 Disease denotes multiorgan failure http://purl.obolibrary.org/obo/MONDO_0043726
T77 5328-5344 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T78 5380-5384 Disease denotes sHLH http://purl.obolibrary.org/obo/MONDO_0015542
T79 5484-5488 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T80 5569-5573 Disease denotes sHLH http://purl.obolibrary.org/obo/MONDO_0015542
T81 5607-5615 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T82 5616-5626 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T83 5736-5741 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T84 5939-5947 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T85 5948-5957 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T86 5978-5993 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T87 5984-5993 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T88 6007-6009 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T90 6045-6047 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T92 6052-6062 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T93 6243-6252 Disease denotes arthritis http://purl.obolibrary.org/obo/MONDO_0005578
T94 6402-6411 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T95 6502-6518 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T96 6542-6544 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T98 6667-6669 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T100 6725-6734 Disease denotes arthritis http://purl.obolibrary.org/obo/MONDO_0005578
T101 6736-6746 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T102 6847-6849 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T104 6896-6905 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T105 7053-7055 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T107 7069-7071 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T109 7197-7207 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T110 7297-7310 Disease denotes polyarthritis http://purl.obolibrary.org/obo/MONDO_0024280
T111 7353-7375 Disease denotes hospitalized infection http://purl.obolibrary.org/obo/MONDO_0043544
T112 7366-7375 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T113 7508-7528 Disease denotes autoimmune disorders http://purl.obolibrary.org/obo/MONDO_0007179
T114 7656-7658 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T116 7802-7812 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T117 7919-7929 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T118 8044-8054 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T119 8337-8347 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T120 8401-8411 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T121 8493-8495 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T123 8502-8519 Disease denotes Diabetes mellitus http://purl.obolibrary.org/obo/MONDO_0005015
T124 8521-8544 Disease denotes cardiovascular diseases http://purl.obolibrary.org/obo/MONDO_0004995
T125 8546-8559 Disease denotes renal failure http://purl.obolibrary.org/obo/MONDO_0001106
T126 8561-8586 Disease denotes interstitial lung disease http://purl.obolibrary.org/obo/MONDO_0015925
T127 8574-8586 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T128 8592-8629 Disease denotes chronic obstructive pulmonary disease http://purl.obolibrary.org/obo/MONDO_0005002
T129 8612-8629 Disease denotes pulmonary disease http://purl.obolibrary.org/obo/MONDO_0005275
T130 8631-8635 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T131 8709-8722 Disease denotes infections in http://purl.obolibrary.org/obo/MONDO_0005550
T132 8723-8725 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T134 8744-8746 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T136 8774-8784 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T137 8932-8950 Disease denotes rheumatic diseases http://purl.obolibrary.org/obo/MONDO_0005554
T138 8954-8970 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T139 9099-9101 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T141 9282-9284 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T143 9348-9360 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T144 9368-9370 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T146 9494-9504 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T147 9582-9591 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T148 9670-9683 Disease denotes infections in http://purl.obolibrary.org/obo/MONDO_0005550
T149 9684-9686 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T151 9784-9797 Disease denotes infections in http://purl.obolibrary.org/obo/MONDO_0005550
T152 9798-9800 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T154 9893-9903 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T155 9942-9944 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T157 10009-10025 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T158 10117-10123 Disease denotes Zoster http://purl.obolibrary.org/obo/MONDO_0005609
T159 10124-10134 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T160 10411-10427 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T161 10512-10516 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T162 10659-10667 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T163 10726-10738 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T164 10893-10902 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T165 11007-11016 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T166 11138-11154 Disease denotes fungal infection http://purl.obolibrary.org/obo/MONDO_0002041
T167 11145-11154 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T168 11356-11360 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T169 11551-11559 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T170 11560-11569 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T171 11728-11736 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T172 11737-11746 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T173 11855-11871 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T174 12094-12102 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T175 12103-12112 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T176 12253-12261 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T177 12326-12335 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T178 12387-12397 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T179 12498-12500 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T181 12586-12588 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T183 12728-12737 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T184 12865-12874 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T185 13048-13070 Disease denotes hospitalized infection http://purl.obolibrary.org/obo/MONDO_0043544
T186 13061-13070 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T187 13297-13306 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T188 13439-13448 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T189 13488-13497 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T190 13510-13512 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T192 14037-14047 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T193 14084-14106 Disease denotes respiratory infections http://purl.obolibrary.org/obo/MONDO_0024355
T194 14165-14174 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T195 14180-14190 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T196 14268-14277 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T197 14613-14622 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T198 14782-14792 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T199 14840-14842 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T201 15011-15017 Disease denotes Zoster http://purl.obolibrary.org/obo/MONDO_0005609
T202 15030-15040 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T203 15254-15256 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T205 15697-15706 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T206 15802-15811 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T207 16135-16145 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T208 16519-16535 Disease denotes virus infections http://purl.obolibrary.org/obo/MONDO_0005108
T209 16585-16593 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T210 16712-16720 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T211 16723-16732 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T212 16773-16781 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T213 16978-16986 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T214 17087-17103 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T215 17155-17163 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T216 17230-17238 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T217 17400-17408 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T218 17650-17655 Disease denotes Ebola http://purl.obolibrary.org/obo/MONDO_0005737
T219 17656-17671 Disease denotes virus infection http://purl.obolibrary.org/obo/MONDO_0005108
T220 17662-17671 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T221 17847-17855 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T222 17858-17867 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T223 18020-18028 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T224 18200-18204 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T225 18539-18541 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T227 18587-18595 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T228 18673-18682 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T229 18745-18753 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T230 18754-18763 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T231 19066-19070 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T232 19161-19170 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T233 19383-19387 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T234 19420-19430 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T235 19515-19530 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T236 19521-19530 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T237 19681-19696 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T238 19687-19696 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T239 19752-19768 Disease denotes fungal infection http://purl.obolibrary.org/obo/MONDO_0002041
T240 19759-19768 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T241 19809-19813 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T242 19816-19851 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T243 19822-19851 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T244 19896-19902 Disease denotes Zoster http://purl.obolibrary.org/obo/MONDO_0005609
T245 20209-20211 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T247 20436-20440 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T248 20997-21001 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T249 21006-21015 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T250 21186-21194 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T251 21462-21471 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T252 21908-21916 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T253 21919-21928 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T254 21986-21990 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T255 22024-22032 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T256 22033-22042 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T257 22116-22119 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T259 22164-22170 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T260 22183-22201 Disease denotes multiorgan failure http://purl.obolibrary.org/obo/MONDO_0043726
T261 22426-22442 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T262 22491-22494 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T264 22565-22573 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T265 22727-22731 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T266 22758-22767 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T267 23004-23012 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T268 23249-23251 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T270 23352-23360 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T271 23361-23370 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T272 23532-23541 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T273 23552-23571 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T274 23847-23850 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T276 23858-23866 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T277 23867-23876 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T278 23982-23988 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T279 24191-24194 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T281 24240-24249 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T282 24281-24289 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T283 24552-24570 Disease denotes SARS-CoV infection http://purl.obolibrary.org/obo/MONDO_0005091
T284 24561-24570 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T285 24714-24720 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T286 25072-25076 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T287 25082-25091 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T288 25177-25185 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T289 25186-25195 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T290 25349-25357 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T291 25985-25994 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T292 26007-26013 Disease denotes Dengue http://purl.obolibrary.org/obo/MONDO_0005502
T293 26021-26026 Disease denotes Ebola http://purl.obolibrary.org/obo/MONDO_0005737
T294 26461-26463 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T296 26636-26639 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T298 26732-26741 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T299 26749-26757 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T300 27194-27196 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T302 27261-27270 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T303 27403-27411 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T304 27599-27608 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T305 28095-28104 Disease denotes Influenza http://purl.obolibrary.org/obo/MONDO_0005812
T306 28427-28431 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T307 28437-28446 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T308 28567-28575 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T309 28576-28585 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T310 28728-28743 Disease denotes viral pneumonia http://purl.obolibrary.org/obo/MONDO_0006012
T311 28734-28743 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T312 28765-28773 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T313 28886-28888 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T315 28924-28945 Disease denotes inflammatory disorder http://purl.obolibrary.org/obo/MONDO_0021166
T316 28947-28949 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T318 28967-28977 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T319 29146-29156 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T320 29182-29184 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T322 29221-29231 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T323 29251-29253 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T325 29324-29332 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T326 29687-29702 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T327 29693-29702 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T328 29757-29761 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T329 29780-29789 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T330 29897-29905 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T331 29906-29916 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T332 29974-29983 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T333 30001-30003 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T335 30164-30173 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T336 30189-30192 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T338 30379-30383 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T339 30538-30553 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T340 30544-30553 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T5 33-34 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T6 70-71 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T7 272-273 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T8 284-289 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T9 462-468 http://purl.obolibrary.org/obo/CLO_0001302 denotes 3], [4
T10 791-794 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T11 799-800 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T12 858-870 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T13 920-921 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T14 996-997 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T15 2194-2207 http://purl.obolibrary.org/obo/PR_000001393 denotes interleukin 6
T16 2345-2349 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T17 2345-2349 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T18 2446-2448 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T19 2765-2766 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T20 2778-2783 http://purl.obolibrary.org/obo/CLO_0009985 denotes focus
T21 2981-2988 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T22 2994-2995 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T23 3271-3274 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T24 3303-3307 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T25 3381-3382 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T26 3390-3398 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T27 3420-3425 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T28 3433-3439 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T29 3433-3439 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T30 3433-3439 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T31 3441-3446 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T32 3441-3446 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T33 3441-3446 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T34 3441-3446 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T35 3448-3470 http://purl.obolibrary.org/obo/UBERON_0005409 denotes gastrointestinal tract
T36 3472-3485 http://purl.obolibrary.org/obo/UBERON_0001981 denotes blood vessels
T37 3472-3485 http://www.ebi.ac.uk/efo/EFO_0000817 denotes blood vessels
T38 3505-3509 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T39 3505-3509 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T40 3523-3533 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T41 3534-3539 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T42 3751-3754 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T43 3920-3924 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T44 3920-3924 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T45 4015-4018 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T46 4332-4333 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T47 5066-5067 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T48 5238-5239 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T49 5539-5540 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T50 5574-5577 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T51 5665-5666 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T52 5688-5701 http://purl.obolibrary.org/obo/PR_000001091 denotes interleukin-1
T53 5712-5716 http://purl.obolibrary.org/obo/PR_000001379 denotes IL-2
T54 5730-5734 http://purl.obolibrary.org/obo/CLO_0053704 denotes IL-8
T55 6286-6298 http://purl.obolibrary.org/obo/UBERON_0001155 denotes colonization
T56 6306-6312 http://purl.obolibrary.org/obo/UBERON_0000982 denotes joints
T57 6465-6466 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T58 6568-6569 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T59 6751-6752 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T60 6810-6812 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T61 6865-6866 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T62 6944-6945 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T63 7085-7086 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T64 7225-7226 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T65 7320-7323 http://purl.obolibrary.org/obo/CLO_0001562 denotes a 2
T66 7320-7323 http://purl.obolibrary.org/obo/CLO_0001563 denotes a 2
T67 7451-7452 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T68 7479-7492 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T69 7577-7585 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T70 7599-7602 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T71 7736-7744 http://purl.obolibrary.org/obo/CLO_0001658 denotes Activity
T72 7778-7779 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T73 7885-7886 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T74 7941-7948 http://purl.obolibrary.org/obo/CLO_0052947 denotes p = .01
T75 7969-7970 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T76 8241-8249 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T77 8295-8296 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T78 8497-8499 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T79 8574-8578 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T80 8574-8578 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T81 9025-9028 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T82 9206-9209 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T83 9296-9298 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T84 9710-9712 http://purl.obolibrary.org/obo/CLO_0053794 denotes 41
T85 9840-9841 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T86 9975-9976 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T87 10042-10043 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T88 10482-10486 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T89 10482-10486 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T90 10669-10671 http://purl.obolibrary.org/obo/CLO_0053799 denotes 45
T91 10721-10725 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T92 10721-10725 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T93 10821-10822 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T94 10904-10905 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T95 10957-10960 http://purl.obolibrary.org/obo/CLO_0050884 denotes ten
T96 11168-11172 http://purl.obolibrary.org/obo/CLO_0037048 denotes CI 1
T97 11322-11323 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T98 11389-11390 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T99 11485-11487 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T100 11906-11909 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T101 12218-12219 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T102 12276-12277 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T103 12440-12441 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T104 12479-12480 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T105 12551-12552 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T106 12703-12704 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T107 12991-12992 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T108 13021-13022 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T109 13186-13188 http://purl.obolibrary.org/obo/CLO_0001407 denotes 52
T110 13191-13192 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T111 13756-13757 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T112 14067-14074 http://purl.obolibrary.org/obo/CLO_0009985 denotes focused
T113 14203-14204 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T114 14333-14334 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T115 15018-15023 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T116 15292-15293 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T117 15310-15313 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T118 15760-15766 http://purl.obolibrary.org/obo/UBERON_0003100 denotes female
T119 15933-15934 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T120 15947-15949 http://purl.obolibrary.org/obo/CLO_0054055 denotes 71
T121 16167-16168 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T122 16334-16338 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T123 16378-16387 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T124 16396-16421 http://purl.obolibrary.org/obo/PR_000024990 denotes type I and II interferons
T125 16519-16524 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T126 16595-16596 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T127 16814-16815 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T128 17010-17017 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T129 17656-17661 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T130 17678-17681 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T131 17710-17711 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T132 17748-17749 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T133 17771-17778 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T134 18082-18087 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T135 18238-18243 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T136 18251-18256 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T137 18599-18600 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T138 18844-18849 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T139 18850-18854 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T140 18896-18904 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T141 19253-19257 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T142 19491-19495 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T143 19903-19908 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T144 20277-20280 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T145 20417-20424 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T146 20678-20683 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T147 20684-20688 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T148 20731-20739 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T149 20886-20891 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T150 20923-20924 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T151 21020-21021 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T152 21047-21050 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T153 21158-21164 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T154 21408-21412 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T155 21408-21412 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T156 21483-21484 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T157 21485-21490 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T158 21800-21801 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T159 22159-22163 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T160 22159-22163 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T161 22203-22205 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T162 22346-22353 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cells
T163 22378-22380 http://purl.obolibrary.org/obo/CLO_0001527 denotes 94
T164 22458-22468 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T165 22482-22489 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T166 22520-22521 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T167 22604-22605 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T168 22779-22780 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T169 22942-22943 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T170 23175-23176 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T171 23283-23286 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T172 23419-23420 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T173 23436-23439 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T174 23766-23767 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T175 23779-23780 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T176 23824-23825 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T177 23961-23962 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T178 23977-23981 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T179 23977-23981 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T180 24021-24024 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T181 24029-24032 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T182 24132-24137 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T183 24132-24137 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T184 24198-24199 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T185 24226-24228 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T186 24326-24337 http://purl.obolibrary.org/obo/CL_0000232 denotes erythrocyte
T187 24501-24503 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T188 24590-24591 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T189 24652-24660 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T190 24709-24713 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T191 24709-24713 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T192 24779-24780 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T193 24890-24895 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T194 24905-24909 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T195 24987-24990 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T196 25111-25116 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T197 25134-25135 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T198 25144-25145 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T199 25196-25199 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T200 25376-25381 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T201 25628-25631 http://purl.obolibrary.org/obo/CLO_0037126 denotes GAK
T202 25686-25691 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T203 25697-25701 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T204 25697-25701 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T205 25702-25707 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T206 25747-25752 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T207 25764-25767 http://purl.obolibrary.org/obo/CLO_0054060 denotes 102
T208 25998-26003 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T209 26014-26019 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T210 26027-26032 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T211 26060-26065 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T212 26374-26377 http://purl.obolibrary.org/obo/CLO_0037126 denotes GAK
T213 26385-26391 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T214 26502-26503 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T215 26660-26676 http://purl.obolibrary.org/obo/PR_000000017 denotes interferon gamma
T216 26880-26881 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T217 27183-27189 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T218 27620-27630 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T219 27665-27674 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T220 27750-27755 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T221 27795-27802 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T222 27819-27824 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T223 27843-27850 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T224 27945-27954 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T225 28105-28106 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T226 28107-28114 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T227 28132-28141 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T228 28220-28229 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T229 28231-28234 http://purl.obolibrary.org/obo/CLO_0053001 denotes 114
T230 28240-28241 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T231 28373-28374 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T232 28794-28795 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T233 28860-28861 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T234 28903-28904 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T235 28958-28959 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T236 29089-29090 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T237 29193-29201 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T238 30351-30354 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T239 30416-30426 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T240 30427-30432 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T241 30485-30493 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T9 300-310 Chemical denotes nucleotide http://purl.obolibrary.org/obo/CHEBI_36976
T10 1659-1683 Chemical denotes immunosuppressive agents http://purl.obolibrary.org/obo/CHEBI_35705
T11 1692-1707 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T12 1754-1759 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T13 1887-1892 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T14 1950-1952 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T15 2013-2024 Chemical denotes Chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T16 2029-2047 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T17 2094-2109 Chemical denotes antiviral drugs http://purl.obolibrary.org/obo/CHEBI_36044
T18 2094-2103 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T19 2104-2109 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T20 2209-2211 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T22 2747-2749 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T23 2847-2867 Chemical denotes anti-rheumatic drugs http://purl.obolibrary.org/obo/CHEBI_35842
T24 2862-2867 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T25 3232-3243 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T26 3354-3366 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T27 3399-3406 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T28 3706-3720 Chemical denotes angiotensin II http://purl.obolibrary.org/obo/CHEBI_2719|http://purl.obolibrary.org/obo/CHEBI_48432|http://purl.obolibrary.org/obo/CHEBI_58506
T31 3706-3717 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T32 3718-3720 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T33 3802-3816 Chemical denotes angiotensin II http://purl.obolibrary.org/obo/CHEBI_2719|http://purl.obolibrary.org/obo/CHEBI_48432|http://purl.obolibrary.org/obo/CHEBI_58506
T36 3802-3813 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T37 3814-3816 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T38 4098-4108 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T39 4112-4123 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T40 5704-5706 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T42 5712-5714 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T44 5718-5720 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T46 5724-5726 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T48 5730-5732 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T50 5787-5806 Chemical denotes chemokine ligand 10 http://purl.obolibrary.org/obo/CHEBI_138157
T51 5797-5803 Chemical denotes ligand http://purl.obolibrary.org/obo/CHEBI_52214
T52 5808-5814 Chemical denotes CXCL10 http://purl.obolibrary.org/obo/CHEBI_138157
T53 5820-5822 Chemical denotes CC http://purl.obolibrary.org/obo/CHEBI_28940
T54 5833-5839 Chemical denotes ligand http://purl.obolibrary.org/obo/CHEBI_52214
T55 6007-6009 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T56 6045-6047 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T57 6542-6544 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T58 6667-6669 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T59 6847-6849 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T60 7053-7055 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T61 7069-7071 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T62 7125-7127 Chemical denotes RR http://purl.obolibrary.org/obo/CHEBI_73811
T63 7170-7172 Chemical denotes RR http://purl.obolibrary.org/obo/CHEBI_73811
T64 7656-7658 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T65 8493-8495 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T66 8723-8725 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T67 8744-8746 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T68 8922-8927 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T69 9015-9021 Chemical denotes NSAIDs http://purl.obolibrary.org/obo/CHEBI_35475
T70 9062-9077 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T71 9079-9081 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T73 9099-9101 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T74 9282-9284 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T75 9313-9315 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T77 9368-9370 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T78 9642-9644 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T80 9684-9686 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T81 9798-9800 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T82 9823-9825 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T84 9942-9944 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T85 9964-9966 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T87 10198-10200 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T89 10232-10234 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T91 10581-10583 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T93 10856-10858 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T95 11059-11061 Chemical denotes RR http://purl.obolibrary.org/obo/CHEBI_73811
T96 11156-11158 Chemical denotes RR http://purl.obolibrary.org/obo/CHEBI_73811
T97 11303-11305 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T99 11471-11473 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T101 11588-11590 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T103 11774-11776 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T105 11831-11837 Chemical denotes NSAIDs http://purl.obolibrary.org/obo/CHEBI_35475
T106 11896-11905 Chemical denotes Ibuprofen http://purl.obolibrary.org/obo/CHEBI_5855
T107 12168-12174 Chemical denotes NSAIDs http://purl.obolibrary.org/obo/CHEBI_35475
T108 12498-12500 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T109 12586-12588 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T110 12667-12682 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T111 12765-12767 Chemical denotes RR http://purl.obolibrary.org/obo/CHEBI_73811
T112 12890-12892 Chemical denotes RR http://purl.obolibrary.org/obo/CHEBI_73811
T113 13075-13087 Chemical denotes methotrexate http://purl.obolibrary.org/obo/CHEBI_44185|http://purl.obolibrary.org/obo/CHEBI_50681
T115 13098-13100 Chemical denotes RR http://purl.obolibrary.org/obo/CHEBI_73811
T116 13129-13147 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T117 13158-13160 Chemical denotes RR http://purl.obolibrary.org/obo/CHEBI_73811
T118 13329-13332 Chemical denotes MTX http://purl.obolibrary.org/obo/CHEBI_44185
T119 13334-13336 Chemical denotes RR http://purl.obolibrary.org/obo/CHEBI_73811
T120 13510-13512 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T121 14826-14836 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T122 14840-14842 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T123 14926-14937 Chemical denotes tofacitinib http://purl.obolibrary.org/obo/CHEBI_71200
T124 15057-15068 Chemical denotes tofacitinib http://purl.obolibrary.org/obo/CHEBI_71200
T125 15254-15256 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T126 15567-15578 Chemical denotes tofacitinib http://purl.obolibrary.org/obo/CHEBI_71200
T127 15772-15782 Chemical denotes prednisone http://purl.obolibrary.org/obo/CHEBI_8382
T128 16019-16029 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T129 16368-16377 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T130 16407-16409 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T131 16551-16561 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T132 16606-16626 Chemical denotes anti-rheumatic drugs http://purl.obolibrary.org/obo/CHEBI_35842
T133 16621-16626 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T134 17047-17062 Chemical denotes antiviral drugs http://purl.obolibrary.org/obo/CHEBI_36044
T135 17047-17056 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T136 17057-17062 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T137 17262-17267 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T138 17322-17332 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T139 17334-17343 Chemical denotes ribavirin http://purl.obolibrary.org/obo/CHEBI_63580
T140 17349-17368 Chemical denotes lopinavir-ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T141 17349-17358 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T142 17359-17368 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T143 17464-17483 Chemical denotes lopinavir-ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T144 17464-17473 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T145 17474-17483 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T146 17566-17576 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T147 17581-17590 Chemical denotes adenosine http://purl.obolibrary.org/obo/CHEBI_16335
T148 17722-17731 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T149 17888-17907 Chemical denotes lopinavir-ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T150 17888-17897 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T151 17898-17907 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T152 17957-17962 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T153 18499-18504 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T154 18539-18541 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T155 18721-18741 Chemical denotes anti-rheumatic drugs http://purl.obolibrary.org/obo/CHEBI_35842
T156 18736-18741 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T157 18775-18786 Chemical denotes Chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T158 19000-19002 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T160 19005-19015 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T161 19435-19445 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T162 19536-19542 Chemical denotes NSAIDs http://purl.obolibrary.org/obo/CHEBI_35475
T163 19776-19787 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T164 19916-19926 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T165 19928-19934 Chemical denotes NSAIDs http://purl.obolibrary.org/obo/CHEBI_35475
T166 19937-19973 Chemical denotes nonsteroidal anti-inflammatory drugs http://purl.obolibrary.org/obo/CHEBI_35475
T167 19950-19973 Chemical denotes anti-inflammatory drugs http://purl.obolibrary.org/obo/CHEBI_35472
T168 19968-19973 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T169 19981-19992 Chemical denotes Chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T170 19993-20011 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T171 20012-20023 Chemical denotes Chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T172 20028-20046 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T173 20077-20082 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T174 20209-20211 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T175 20233-20244 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T176 20351-20355 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T177 20616-20627 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T178 20949-20953 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T179 21035-21046 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T180 21251-21256 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T181 21346-21357 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T182 21599-21617 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T183 21671-21682 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T184 21941-21943 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T186 21950-21952 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T188 22585-22587 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T190 22594-22596 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T192 22796-22798 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T194 23031-23042 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T195 23078-23084 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T196 23196-23207 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T197 23209-23211 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T199 23249-23251 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T200 23384-23386 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T202 23427-23429 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T203 23695-23697 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T205 23700-23709 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T206 24113-24115 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T208 24516-24526 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T209 24674-24685 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T210 24753-24760 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T211 25027-25037 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T212 25303-25313 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T213 25572-25579 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T214 25890-25899 Chemical denotes erlotinib http://purl.obolibrary.org/obo/CHEBI_114785
T215 25901-25910 Chemical denotes sunitinib http://purl.obolibrary.org/obo/CHEBI_38940
T216 25912-25923 Chemical denotes ruxolitinib http://purl.obolibrary.org/obo/CHEBI_66919
T217 26312-26321 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T218 26461-26463 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T219 26514-26523 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T220 26651-26653 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T222 26660-26670 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T223 26671-26676 Chemical denotes gamma http://purl.obolibrary.org/obo/CHEBI_30212
T224 26835-26838 Chemical denotes CYP http://purl.obolibrary.org/obo/CHEBI_38559
T225 26839-26843 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T226 26875-26879 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T227 26945-26960 Chemical denotes antiviral drugs http://purl.obolibrary.org/obo/CHEBI_36044
T228 26945-26954 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T229 26955-26960 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T230 26969-26988 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T231 26969-26978 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T232 26979-26988 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T233 26993-27003 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T234 27026-27037 Chemical denotes tofacitinib http://purl.obolibrary.org/obo/CHEBI_71200
T235 27160-27170 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T236 27194-27196 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T237 27438-27449 Chemical denotes ruxolitinib http://purl.obolibrary.org/obo/CHEBI_66919
T238 27728-27738 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T239 28886-28888 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T240 28947-28949 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T241 29064-29069 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T242 29182-29184 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T243 29251-29253 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T244 29624-29626 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T246 29791-29802 Chemical denotes Chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T247 29807-29825 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T248 30001-30003 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T249 30040-30042 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T251 30045-30055 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T252 30059-30070 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 1816-1828 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T2 3048-3063 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T3 3166-3178 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T4 3573-3588 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T5 4799-4810 http://purl.obolibrary.org/obo/GO_0006412 denotes translation
T6 4836-4849 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T7 5328-5344 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T8 5742-5750 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T9 5742-5750 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T10 5742-5750 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T11 5742-5750 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T12 5978-5993 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T13 6502-6518 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T14 8954-8970 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T15 9348-9360 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T16 10009-10025 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T17 10251-10278 http://purl.obolibrary.org/obo/GO_0050777 denotes inhibit the immune response
T18 10263-10278 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T19 10367-10388 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T20 10411-10427 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T21 10726-10738 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T22 11855-11871 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T23 16334-16356 http://purl.obolibrary.org/obo/GO_0002456 denotes cell-mediated immunity
T24 16334-16356 http://purl.obolibrary.org/obo/GO_0002449 denotes cell-mediated immunity
T25 16378-16387 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T26 17087-17103 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T27 18850-18861 http://purl.obolibrary.org/obo/GO_0140253 denotes cell fusion
T28 18850-18861 http://purl.obolibrary.org/obo/GO_0045026 denotes cell fusion
T29 18850-18861 http://purl.obolibrary.org/obo/GO_0000768 denotes cell fusion
T30 18850-18861 http://purl.obolibrary.org/obo/GO_0000747 denotes cell fusion
T31 18887-18904 http://purl.obolibrary.org/obo/GO_0038024 denotes receptor activity
T32 18924-18946 http://purl.obolibrary.org/obo/GO_0033578 denotes terminal glycosylation
T33 18933-18946 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T34 19226-19243 http://purl.obolibrary.org/obo/GO_0046718 denotes viral penetration
T35 19283-19294 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis
T36 19464-19481 http://purl.obolibrary.org/obo/GO_0046718 denotes viral penetration
T37 19515-19530 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T38 19561-19578 http://purl.obolibrary.org/obo/GO_0046718 denotes viral penetration
T39 19681-19696 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T40 20386-20392 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T41 20684-20695 http://purl.obolibrary.org/obo/GO_0140253 denotes cell fusion
T42 20684-20695 http://purl.obolibrary.org/obo/GO_0045026 denotes cell fusion
T43 20684-20695 http://purl.obolibrary.org/obo/GO_0000768 denotes cell fusion
T44 20684-20695 http://purl.obolibrary.org/obo/GO_0000747 denotes cell fusion
T45 20722-20739 http://purl.obolibrary.org/obo/GO_0038024 denotes receptor activity
T46 20763-20785 http://purl.obolibrary.org/obo/GO_0033578 denotes terminal glycosylation
T47 20772-20785 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T48 22137-22154 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T49 22137-22154 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T50 22402-22417 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T51 22426-22442 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T52 25296-25313 http://purl.obolibrary.org/obo/GO_0033673 denotes kinase inhibitors
T53 25390-25419 http://purl.obolibrary.org/obo/GO_0006898 denotes receptor-mediated endocytosis
T54 25408-25419 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis
T55 25449-25492 http://purl.obolibrary.org/obo/GO_2000369 denotes regulators of clathrin-mediated endocytosis
T56 25463-25492 http://purl.obolibrary.org/obo/GO_0072583 denotes clathrin-mediated endocytosis
T57 25481-25492 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis
T58 25600-25606 http://purl.obolibrary.org/obo/GO_0016538 denotes cyclin
T59 26607-26628 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T60 27343-27372 http://purl.obolibrary.org/obo/GO_0072583 denotes clathrin-mediated endocytosis
T61 27361-27372 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis
T62 27519-27542 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune responses
T63 27554-27571 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T64 27554-27571 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T65 27634-27647 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T66 27660-27682 http://purl.obolibrary.org/obo/GO_0097696 denotes STAT signaling pathway
T67 27665-27682 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T68 27665-27674 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T69 27945-27962 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T70 27945-27954 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T71 28063-28072 http://purl.obolibrary.org/obo/GO_0016032 denotes virulence
T72 28063-28072 http://purl.obolibrary.org/obo/GO_0009405 denotes virulence
T73 28132-28141 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T74 28220-28229 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T75 29687-29702 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T76 30538-30553 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T9 0-15 Sentence denotes 1 Introduction
T10 16-223 Sentence denotes In December 2019 a new type of pneumonia supported by a novel member of the coronoviridae family named SARS-CoV-2 (severe acute respiratory coronavirus 2 syndrome) developed from Wuhan Province in China [1].
T11 224-340 Sentence denotes Phylogenetic analysis demonstrated that this is a different virus with ~80% nucleotide identity with SARS-CoV-1 [2].
T12 341-481 Sentence denotes The disease caused by SARS-CoV-2 is characterized by dry cough, fever, dyspnea and fatigue, accompanied by lymphopenia [[3], [4], [5], [6]].
T13 482-749 Sentence denotes In more severe cases (apparently up to 15–20% of infected patients) the picture may become more complicated by the onset of interstitial pneumonia with alveolar damage, which clinically can lead to severe Acute Respiratory Distress Syndrome (ARDS) and even death [7].
T14 750-1026 Sentence denotes Since the initial outbreak, the epidemic has had a rapid global spread worldwide which led the World Health Organization (WHO) to declare the disease now called COVID-19 a Public Health Emergency of International Concern on 30th January 2020 and a pandemic on 11th March 2020.
T15 1027-1201 Sentence denotes The epidemiological picture is constantly evolving, and data updated as of March 17th count 159 countries involved with more than 185,000 cases and 7500 confirmed deaths [8].
T16 1202-1400 Sentence denotes In this context of growing health emergency, clarifying the relationship between COVID-19 and the population of fragile patients suffering from immune-rheumatological diseases is absolutely crucial.
T17 1401-1764 Sentence denotes On the one hand, the rapid and uncontrolled spread of the epidemic can clearly generate even more concerns in rheumatic patients, which are intrinsically characterized by an increased infectious risk due to the disease itself and to the iatrogenic effect of immunosuppressive agents such as corticosteroids and synthetic or biological disease-modifying drugs [9].
T18 1765-2012 Sentence denotes On the other hand, the growing knowledge about the pathogenesis of SARS-CoV-2 infection is leading to the introduction of drugs commonly used for the treatment of rheumatoid arthritis (RA) even for the management of more complex cases of COVID-19.
T19 2013-2169 Sentence denotes Chloroquine and hydroxychloroquine have now been permanently included, alongside antiviral drugs, in protocols for the treatment of COVID-19 pneumonia [10].
T20 2170-2450 Sentence denotes In addition, the use of interleukin 6 (IL-6) blockers seems to be very promising for the management of the massive cytokine storm associated to the development of the typical lung damage and the consequent ARDS occurring in the most aggressive patterns of SARS-CoV infection [11].
T21 2451-2665 Sentence denotes Therefore, waiting for observational data on the incidence of COVID-19 in rheumatological patients, the best strategy to manage immune-rheumatological diseases during this emergency period is still far to be clear.
T22 2666-2904 Sentence denotes The purpose of this review is to provide an overview on viral infectious risk in RA patients, with a particular focus on the knowledge about the current new pandemic and the use of anti-rheumatic drugs in this context of health emergency.
T23 2906-2950 Sentence denotes 2 The pathophysiology of COVID-19 infection
T24 2951-3038 Sentence denotes Coronaviruses are the largest viruses with a positive-sense single-stranded-RNA genome.
T25 3039-3227 Sentence denotes The host immune response is by one side essential for the resolution of COVID-19 infection, but it can also be crucial for the pathogenesis of major clinical manifestations of the disease.
T26 3228-3372 Sentence denotes The angiotensin-converting enzyme 2 (ACE2) has been identified as the host cell-surface receptor for SARS-CoV2 envelope spike glycoprotein [12].
T27 3373-3594 Sentence denotes ACE2 is a type I membrane protein expressed on cells in the kidney, heart, gastrointestinal tract, blood vessels, and, importantly, lung AT2 alveolar epithelial cells, which are particularly prone to viral infection [13].
T28 3595-3747 Sentence denotes SARS-CoV-2 infection leads to the downregulation of ACE2 expression, thus resulting in excessive production of angiotensin II by the related enzyme ACE.
T29 3748-3978 Sentence denotes It has been suggested that the stimulation of type 1a angiotensin II receptor (AGTR1A) increases pulmonary vascular permeability, thus potentially explaining the increased lung damage when the expression of ACE2 is decreased [14].
T30 3979-4227 Sentence denotes Due to this mechanism of action, it has been postulated that subjects with diabetes mellitus or hypertension using ACE-inhibitors or angiotensin receptor blockers may have an increase of both the risk of infection and the severity of COVID-19 [15].
T31 4228-4440 Sentence denotes As only scarce evidence supports this hypothesis, the European Society of Cardiology recently published a position statement that strongly recommends continuing these treatments despite the current epidemic [16].
T32 4441-4712 Sentence denotes An additional point to be clarified is also the role of the genetic predisposition for an increased risk of SARS-CoV-2 infection due to ACE2 polymorphisms that have been linked to hypertension, diabetes mellitus, and cerebral stroke, especially in Asian populations [15].
T33 4713-4915 Sentence denotes The viral RNA genome is released into the cytoplasm, and the RNA is uncoated to allow translation of the two polyproteins, transcription of the sub-genomic RNAs and replication of the viral genome [17].
T34 4916-5153 Sentence denotes Progression to ARDS is associated with the upregulation of pro-inflammatory cytokines and chemokines, known as Cytokines Release Syndrome (CRS), with a pattern very similar to that of secondary haemophagocytic lymphohistiocytosis (sHLH).
T35 5154-5353 Sentence denotes In adults, sHLH is an under-recognized, hyperinflammatory syndrome characterized by a massive and fatal hypercytokinaemia with multiorgan failure, most commonly triggered by viral infections [18,19].
T36 5354-5538 Sentence denotes Main clinical features of sHLH include unremitting fever, hyperferritinaemia and cytopenias, and pulmonary involvement (including ARDS) occurring in approximately 50% of patients [20].
T37 5539-5858 Sentence denotes A cytokine profile resembling sHLH has been reported in most severe COVID-19 infections, characterized by increased levels of a number of cytokines (interleukin-1β [IL-1β], IL-2, IL-6, IL-7, IL-8, tumor necrosis factor-α [TNF]) and chemokines (CXC-chemokine ligand 10 [CXCL10] and CC-chemokine ligand 2 [CCL2]) [21,22].
T38 5859-5958 Sentence denotes The management of this cytokine storm is one of the major unmet needs regarding COVID-19 infection.
T39 5960-6019 Sentence denotes 3 Is the risk of viral infection increased in RA patients?
T40 6020-6139 Sentence denotes The relationship between RA and infectious diseases is very complex and can be interpreted in two different directions.
T41 6140-6434 Sentence denotes On the one hand, in fact, the potential role of external microorganisms in producing acute and chronic arthritis in the form of either the direct colonization of the joints by the pathogen or the aberrant autoimmune reaction produced by the host response to the infection is well known [23,24].
T42 6435-6675 Sentence denotes Few studies have investigated a potential link between respiratory viral infections and the development of RA [25] and in particular a Korean study reported parainfluenza and coronavirus to be associated with the number of incident RA [26].
T43 6676-6827 Sentence denotes In addition, in patients with overt inflammatory arthritis, infections are a major concern as they can contribute to disease flares [[27], [28], [29]].
T44 6828-6943 Sentence denotes On the other hand, RA patients carry a documented increased risk of infection compared with the general population.
T45 6944-7213 Sentence denotes A population-based study by Doran and colleagues compared two matched groups of 609 patients with or without RA showing that RA patients had a significantly higher risk of serious (RR 1.53, 95% CI 1.41–1.65) and hospitalized (RR 1.88, 95% CI 1.71–2.07) infections [30].
T46 7214-7412 Sentence denotes Similarly, a prospective cohort study conducted on 2108 patients with inflammatory polyarthritis reported a 2- to 4-fold increased risk of hospitalized infection compared to healthy population [31].
T47 7413-7586 Sentence denotes This trend is primarily the result of a general impairment of the immune system typical of all autoimmune disorders and strictly dependent on the degree of disease activity.
T48 7587-7955 Sentence denotes In fact, it has been demonstrated by an analysis conducted in 16,242 RA patients from the US CORRONA registry that each 0.6 unit increase in Disease Activity Score 28 (DAS28) corresponded to a 25% increased rate of infections requiring hospitalization (Incident rate ratio [IRR] 1.25, p = .03) and a 4% increased rate of outpatient infections (IRR 1.04, p = .01) [32].
T49 7956-8367 Sentence denotes In addition, a subsequent report from the same registry showed that the risk of serious infections increased progressively from patients achieving clinical remission to those achieving low (adjusted IRR 1.69, 95% CI 1.32–2.15) or moderate (adjusted IRR 1.30, 95% CI 1.09–1.56) disease activity, demonstrating the importance of maintaining a good disease control in order to reduce infectious complications [33].
T50 8368-8501 Sentence denotes Another important determinant of infectious risk is the presence of comorbidities, which very often complicate the course of RA [34].
T51 8502-8734 Sentence denotes Diabetes mellitus, cardiovascular diseases, renal failure, interstitial lung disease, and chronic obstructive pulmonary disease (COPD) are all concomitant disorders associated with an increased incidence of infections in RA [27,35].
T52 8735-8903 Sentence denotes Finally, RA can also be complicated by infections caused by the iatrogenic effect of immunosuppressive therapies, which will be discussed in detail in the next section.
T53 8905-8988 Sentence denotes 4 The impact of drugs for rheumatic diseases on viral infections: what do we know?
T54 8990-9021 Sentence denotes 4.1 Corticosteroids and NSAIDs
T55 9022-9300 Sentence denotes It has now been more than 70 years that corticosteroids (CS) are pivotal for RA management and their role as remission inducer and bridging therapy for the management of disease flare has recently been renewed by the latest update of EULAR recommendations for RA treatment [36].
T56 9301-9600 Sentence denotes Even though CS efficacy in rapidly suppressing inflammation during RA initial course or flares is well recognized [37], their downside is the broad spectrum of adverse events, including severe infections and the high risk of developing comorbidities further increasing the risk of infection [27,38].
T57 9601-9870 Sentence denotes Although RCTs conducted in the past with CS showed no higher risk of infections in RA patients [[39], [40], [41]], cohort and case-control studies reported increased rates of overall infections in RA patients treated with CS, according to a dose-dependent fashion [42].
T58 9871-10026 Sentence denotes The majority of these infectious events are of bacterial etiology, but RA patients receiving CS exhibit a greater risk of developing even viral infections.
T59 10027-10225 Sentence denotes As an example, a 2012 retrospective cohort-study demonstrated an increased risk of Herpes Zoster infections with an incidence rate of 8.54 cases per 1000 patient-years in CS treated population [29].
T60 10226-10522 Sentence denotes Thus, CS on the one hand inhibit the immune response and delay the clearance of the pathogen, while on the other hand they suppress the host inflammatory response, which in the case of viral infections of the respiratory tract is the major responsible for lung damage and occurrence of ARDS [43].
T61 10523-10772 Sentence denotes The latter represented the rational for the widely use of CS for the management of Middle East respiratory syndrome (MERS)-CoV [44] and SARS-CoV [45] outbreaks, both histologically characterized by lung inflammation and diffuse alveolar damage [46].
T62 10773-10903 Sentence denotes However, evidence from the literature points to a predominantly negative effect of CS in the management of this type of infection.
T63 10904-11096 Sentence denotes A 2019 systematic review and meta-analysis including ten observational studies (n = 6548) conducted in influenza reported increased mortality (risk ratio [RR] 1.75, 95% CI 1.3–2.4; p = .0002),
T64 11097-11311 Sentence denotes increased rate of secondary bacterial or fungal infection (RR 2·0, 95% CI 1·0–3·8; p = .04), and longer stay in an intensive care unit (mean difference 2.1, 95% CI 1.2–3.1; p < .0001) in patients receiving CS [47].
T65 11312-11489 Sentence denotes Moreover, a review exploring treatments for ARDS, including six studies with a total of 574 patients, concluded that insufficient evidence exists to recommend CS treatment [48].
T66 11490-11658 Sentence denotes Overall, no clear reason exists to expect that patients with COVID-19 infection will benefit from CS, and they might be more likely to be harmed with such therapy [49].
T67 11659-11818 Sentence denotes In fact, current interim guidance from WHO on clinical management of COVID-19 infection advises against the use of CS unless indicated for another reason [10].
T68 11819-11895 Sentence denotes The role of NSAIDs in the course of viral infections is still controversial.
T69 11896-12138 Sentence denotes Ibuprofen has been demonstrated to induce an overexpression of ACE2 when used in diabetic rats [50] and this effect might theoretically increase the susceptibility and worsen the clinical course of COVID-19 infection in treated patients [15].
T70 12139-12336 Sentence denotes In addition, the use of both NSAIDs and acetaminophen could be associated with a masking of the fever rise during COVID-19, resulting in a delay in diagnosis and proper management of the infection.
T71 12338-12351 Sentence denotes 4.2 csDMARDs
T72 12352-12642 Sentence denotes The most comprehensive analysis of infectious risk in patients treated with csDMARDs is a retrospective, longitudinal study of a population-based RA cohort using an administrative database including a total of 27,710 individuals with RA and providing 162,710 person-years of follow-up [51].
T73 12643-12916 Sentence denotes Use of csDMARDs without corticosteroids was associated with a small decrease in mild infection risk (adjusted rate ratio [RR] 0.90, 95% confidence interval [95% CI] 0.88–0.93) and was not associated with increased serious infection risk (adjusted RR 0.92, 95% CI 0.85–1.0).
T74 12917-13190 Sentence denotes Similarly, another retrospective analysis conducted on 1993 patients from a claim database demonstrated a slightly reduced risk of hospitalized infection for methotrexate (adjusted RR 0.81, 95% CI 0.70–0.93) and hydroxychloroquine (adjusted RR 0.74, 95% CI 0.62–0.89) [52].
T75 13191-13337 Sentence denotes A recent systematic review and meta-analysis of the literature confirmed the lack of an increased risk of infection in patients receiving MTX (RR:
T76 13338-13368 Sentence denotes 1.14; 95% CI, 0.98–1.34) [53].
T77 13369-13461 Sentence denotes However, all these reports provided no data on the risk of stratified infection by pathogen.
T78 13463-13475 Sentence denotes 4.3 bDMARDs
T79 13476-13639 Sentence denotes The risk of infection observed in RA patients treated with bDMARDs is generally considered slightly higher (from 1.5- up to 2-fold) compared with csDMARDs [27,54].
T80 13640-13909 Sentence denotes This evidence recurred in most RCTs [55] and observational registry studies [[56], [57], [58]] and was confirmed by a recent meta-analysis which showed that this risk is progressively increasing in relation to the use of bDMARDs at higher than recommended dosages [59].
T81 13910-14061 Sentence denotes Following the results of comparative metanalyses and real-life studies, abatacept is accepted as the safest bDMARD in terms of infectious risk [60,61].
T82 14062-14147 Sentence denotes Data focused on viral respiratory infections in bDMARD cohort are still very limited.
T83 14148-14472 Sentence denotes The incidence of influenza-like infections observed in a cohort of 159 Italian patients treated with bDMARDs during the influenza season 2009–2010 was higher than the value reported in a wide sample of Italian population in the same period, even though no important complications or hospitalizations have been reported [62].
T84 14473-14720 Sentence denotes Overall, post-marketing experience is relatively reassuring that anti-TNF treated patients may not be at any specifically increased risk of influenza and that severe adverse outcomes, including death, do not appear to be exceedingly frequent [63].
T85 14722-14735 Sentence denotes 4.4 tsDMARDs
T86 14736-15046 Sentence denotes The overall risk of serious and opportunistic infections observed with Janus Kinase (JAK) inhibitors in RA patients is roughly comparable with bDMARDs [64,65], although these early years of tofacitinib and baricitinib use have raised the issue of an increased risk of Herpes Zoster virus (HZV) infections [66].
T87 15047-15291 Sentence denotes Data from tofacitinib pooled population enrolled in RCTs showed an HZV incidence rate of 4.0 per 100 patient-years (with greater incidence in geographic area with high HZV endemicity), doubling the rates of RA patients not receiving JAKis [67].
T88 15292-15443 Sentence denotes A similar picture has also been observed in the overall development program of baricitinib, with an incidence rate of 3.2 cases per patient-years [68].
T89 15444-15748 Sentence denotes The subsequent real-life experience from US claim databases revealed that the risk of HZV was higher in patients receiving tofacitinib compared to those treated with abatacept (aHR 2.01 (95% CI 1.40; 2.88) [69], and the risk of serious hospitalized HZV infection is 2-fold higher versus all bDMARDs [70].
T90 15749-15951 Sentence denotes Older age, female sex, prednisone >7.5 mg/day, prior infection, and greater number of hospitalizations were associated with increased HZV risk, whereas vaccination was associated with a lower risk [71].
T91 15952-16199 Sentence denotes More recent reports from RCTs conducted with novel JAK-1 selective inhibitors upadacitinib and filgotinib have basically confirmed the same trend, suggesting that the increase in HZV infections can be considered as a class effect of JAKis [72,73].
T92 16200-16458 Sentence denotes Although the exact mechanism by which HZV reactivation occurs in the context of JAK inhibition is unclear, the downregulation of both cell-mediated immunity and innate antiviral signaling through type I and II interferons (IFN) is likely to be involved [74].
T93 16459-16562 Sentence denotes Currently, no data are available on the risk of respiratory virus infections carried by JAK inhibitors.
T94 16564-16627 Sentence denotes 5 The management of COVID-19: a room for anti-rheumatic drugs?
T95 16628-16915 Sentence denotes Currently, vaccines and approved targeted therapeutics for the treatment of the new SARS-CoV-2 infection are still lacking and the management of COVID-19 is only supportive, even though a multitude of compounds are now under investigation for the treatment of this emerging disease [75].
T96 16916-17104 Sentence denotes The need to urgently identify an effective approach to manage COVID-19 led to the strategy of testing the efficacy of the existing antiviral drugs commonly used for other viral infections.
T97 17105-17414 Sentence denotes In particular, considering the similarity between SARS-CoV-2 and other Betacoronavirus associated with previous epidemics as SARS-CoV and MERS-Cov, the same drugs used with controversial results for these conditions (interferon, ribavirin, and lopinavir-ritonavir) have been considered even for COVID-19 [76].
T98 17415-17552 Sentence denotes Anecdotal cases have demonstrated the ability of lopinavir-ritonavir to significantly reduce viral load and improve disease outcome [77].
T99 17553-17873 Sentence denotes In addition, remdesivir, an adenosine analogue currently under development for the management of Ebola virus infection [78], has been recently recognized as a promising antiviral therapy against a wide spectrum of RNA viruses [79] and showed good preliminary in vitro results in the control of SARS-CoV-2 infection [80].
T100 17874-18034 Sentence denotes Consequently, lopinavir-ritonavir and remdesevir are currently the only anti-viral drugs included in the more severe case management protocols of COVID-19 [10].
T101 18035-18265 Sentence denotes Recent reports described the potential role of human monoclonal antibodies that bind the coronavirus spike receptor binding domain, leading to the neutralization of SARS-CoV2 capability to interact with human target cells [81,82].
T102 18266-18445 Sentence denotes However, at the moment these can only be considered as potential treatment options for the future, but they are obviously not available for the management of the current pandemic.
T103 18446-18694 Sentence denotes Beyond the use of specific anti-viral products, many drugs commonly used in the treatment of RA have been proposed as possible therapies for COVID-19 as a consequence of the increased knowledge about the pathophysiology of the infection (Table 1 ).
T104 18695-18764 Sentence denotes Table 1 Potential role of anti-rheumatic drugs in COVID-19 infection.
T105 18765-18774 Sentence denotes PROS CONS
T106 18775-18980 Sentence denotes Chloroquine Anti-viral effect (increase of endosomal pH required for virus/cell fusion, inhibition of toll-like receptor activity, interference with terminal glycosylation of the cellular receptor ACE 2) –
T107 18981-18999 Sentence denotes Hydroxychloroquine
T108 19000-19131 Sentence denotes IL-6 inhibitors Treatment of cytokine storm manifestations during ARDS Lack of definite criteria to identify patients to be treated
T109 19132-19195 Sentence denotes Potential community-acquired pneumonia due to immunosuppression
T110 19196-19332 Sentence denotes Baricitinib Interference with viral penetration into the cell by blocking NAK-mediated endocytosis Impairment of IFN anti-viral response
T111 19333-19430 Sentence denotes Treatment of cytokine storm manifestations during ARDS Increased risk of secondary HZV infections
T112 19431-19535 Sentence denotes TNF-inhibitors Interference with viral penetration into the cell Slight increase in viral infection risk
T113 19536-19604 Sentence denotes NSAIDs – Facilitation of viral penetration by overexpression of ACE2
T114 19605-19644 Sentence denotes Delay in diagnosis due to fever masking
T115 19645-19696 Sentence denotes Corticosteroids – Increased risk of viral infection
T116 19697-19768 Sentence denotes Increased mortality and risk of secondary bacterial or fungal infection
T117 19769-19909 Sentence denotes ACE2 = angiotensin converting enzyme 2, ARDS = acute respiratory distress syndrome, NAK = numb-associated kinase; HZV = Herpes Zoster virus,
T118 19910-19974 Sentence denotes IFN = interferon, NSAIDs = nonsteroidal anti-inflammatory drugs.
T119 19976-20011 Sentence denotes 5.1 Chloroquine/hydroxychloroquine
T120 20012-20217 Sentence denotes Chloroquine and hydroxychloroquine are widely used anti-malarial drugs with well-known immunomodulatory properties that have extended their use to several immuno-rheumatological diseases including RA [83].
T121 20218-20318 Sentence denotes The ability of chloroquine to produce an anti-viral effect has been known since the late 1960s [84].
T122 20319-20575 Sentence denotes Several mechanisms by which the drug is able to interfere with the growth and spread of different viruses (including SARS coronavirus) have been demonstrated in in vitro studies [85], even though the subsequent in vivo experience was controversial [86,87].
T123 20576-20836 Sentence denotes At clinically admissible concentrations chloroquine is able to increase the endosomal pH required for virus/cell fusion, to inhibit the toll-like receptor activity, and to interfere with terminal glycosylation of the cellular receptor ACE 2 [[88], [89], [90]].
T124 20837-21016 Sentence denotes All these functions may negatively influence the virus-receptor binding, resulting in a potential effect of the drug on both entry and post-entry stages of the SARS CoV infection.
T125 21017-21278 Sentence denotes As a consequence, chloroquine has recently been included in at least 10 randomized controlled trials currently ongoing in China, where it is tested for the treatment of COVID-19 under various combination protocols with the anti-viral drugs mentioned above [91].
T126 21279-21583 Sentence denotes Interim results from more than 100 patients have demonstrated that chloroquine is superior to the control treatment in improving lung imaging findings, inhibiting the exacerbation of pneumonia, promoting a virus negative conversion, and shortening the disease course at different levels of severity [92].
T127 21584-21743 Sentence denotes More recently, hydroxychloroquine was demonstrated to be more 3-times more potent than chloroquine in an in vitro study based on pharmacokinetic models (PBPK).
T128 21744-21934 Sentence denotes An oral loading dose of 400 mg twice daily, followed by a maintenance dose of 200 mg given twice daily for 4 days seems to be the best option for the management of SARS-CoV-2 infection [93].
T129 21936-21963 Sentence denotes 5.2 IL-6 and IL-1 blockers
T130 21964-22207 Sentence denotes As already described, ARDS occurring in most severe case of COVID-19 infection is mainly produced by the massive release of pro-inflammatory mediators (CRS) associated with viral replication and lung injury, leading to multiorgan failure [22].
T131 22208-22382 Sentence denotes Moreover, the high levels of these cytokines have been reported to be inversely related to the absolute lymphocytes count, with surviving T-cells functionally exhausted [94].
T132 22383-22584 Sentence denotes Since an effective immune response against viral infections depends on the activation of cytotoxic T cells, CRS might be associated with a decreased viral clearance, contributing to COVID-19 worsening.
T133 22585-22768 Sentence denotes IL-6 and IL-1 play a pivotal role in this hyperinflammatory condition, suggesting the potential use of their blockers as treatment option for SARS-CoV2 related interstitial pneumonia.
T134 22769-22941 Sentence denotes Data from a phase 3 RCT of IL-1 blockade (anakinra) in sepsis showed significant survival benefit in patients with hyperinflammation, without increased adverse events [95].
T135 22942-23174 Sentence denotes A small retrospective study on 21 patients affected by severe COVID-19 demonstrated that tocilizumab improved CT scan abnormalities and oxygen saturation, and normalized CRP levels and lymphocytes count in most of the patients [96].
T136 23175-23638 Sentence denotes A multicentre RCT of tocilizumab (IL-6 receptor blocker licensed for both RA and cytokine release syndrome) has been approved in China and is currently ongoing in patients with COVID-19 pneumonia and elevated IL-6 levels (ChiCTR2000029765) and a phase II study has been approved by the Italian Regulatory Drug Agency (AIFA) and will enrol 330 patients with pneumonia and early respiratory failure, with 1-month mortality reduction as primary outcome (TOCIVID-19).
T137 23639-23801 Sentence denotes Moreover, the company that produces the second marketed IL-6 inhibitor sarilumab recently announced its intention to undertake a study with a similar design [97].
T138 23802-23944 Sentence denotes The identification of a unique definition of CRS during COVID-19 infection is crucial to better customize the management of critical patients.
T139 23945-24295 Sentence denotes The presence of a large area of lung injury (≥50%) with decreased levels of CD4 and CD8 T-lymphocytes (lower than 50% of minimum normal range), and increased levels of IL-6 in peripheral blood have been recognized as the greatest risk factors of CRS in a retrospective analysis of 11 critically pneumonia Chinese patients infected with COVID-19 [98].
T140 24296-24505 Sentence denotes Increasing ferritin level and erythrocyte sedimentation rate or decreasing platelet counts would be additional parameters potentially useful to discriminate patients requiring immunosuppressive treatment [22].
T141 24507-24526 Sentence denotes 5.3 TNF inhibitors
T142 24527-24726 Sentence denotes As previously described, SARS-CoV infection is associated with a downregulation of ACE2 expression coupled with an increased activity of the renin-angiotensin system responsible for lung injury [14].
T143 24727-24915 Sentence denotes Moreover, the viral spike protein is able to induce a TNF-α-converting enzyme (TACE)-dependent shedding of the ACE2 ectodomain, crucial for the penetration of the virus into the cell [99].
T144 24916-25130 Sentence denotes Since this process seems to be strictly coupled to TNFα production, it has been postulated that the use of TNF inhibitors may be effective in reducing both SARS-CoV2 infection and the consequent organ damage [100].
T145 25131-25283 Sentence denotes As a result, a study evaluating adalimumab in COVID-19 infection has recently been registered in the Chinese Clinical Trial Registry (ChiCTR2000030089).
T146 25285-25313 Sentence denotes 5.4 Janus kinase inhibitors
T147 25314-25425 Sentence denotes As previously described in detail, SARS-CoV-2 enters targeted cells through receptor-mediated endocytosis [12].
T148 25426-25639 Sentence denotes Some of the identified regulators of clathrin-mediated endocytosis are members of the numb-associated kinase (NAK) family, such as AP2-associated protein kinase 1 (AAK1) and cyclin G-associated kinase (GAK) [101].
T149 25640-25769 Sentence denotes Inhibition of AAK1 may stop the access of the virus into lung cells and also the intracellular assembly of virus particles [102].
T150 25770-25850 Sentence denotes Of 47 AAK1 blockers approved for medical use, 6 inhibit AAK1 with high affinity.
T151 25851-26072 Sentence denotes These include oncologic agents such as erlotinib, sunitinib, ruxolitinib, and fedratinib, which have all been demonstrated to inhibit infection of cells by Dengue virus, Ebola virus, and respiratory syncytial virus [103].
T152 26073-26291 Sentence denotes Unfortunately, all these compounds are able to produce adequate NAK inhibition only at doses significantly higher than those normally used in clinical practice and therefore potentially toxic for the patient [104,105].
T153 26292-26488 Sentence denotes Conversely, the JAK inhibitor baricitinib is able to effectively inhibit AAK1 and GAK at the plasma concentration obtained with the approved dosage for the treatment of RA (2 to 4 mg daily) [106].
T154 26489-26768 Sentence denotes Moreover, as a selective inhibitor of JAK 1 and 2, baricitinib is also able to produce an important dampening of host inflammatory response due to CRS (including IL-6 and interferon gamma) responsible for the more severe forms of interstitial pneumonia during COVID-19 [107,108].
T155 26769-27010 Sentence denotes Finally, the minimal interaction of baricitinib with the relevant CYP drug-metabolising enzymes makes the drug a possible candidate for inclusion in combination protocols with antiviral drugs such as lopinavir/ritonavir and remdesivir [109].
T156 27011-27271 Sentence denotes Interestingly, tofacitinib shows no detectable inhibition of AAK1 [104], whereas currently no data are available on the possible effect of other JAK inhibitors approved or tested for RA (such as upadacitinib or filgotinib) in relation to coronavirus infection.
T157 27272-27469 Sentence denotes Unexpectedly, the only clinical trial evaluating the potential role of clathrin-mediated endocytosis blockade in the management of COVID-19 is currently ongoing with ruxolitinib (ChiCTR2000029580).
T158 27470-27615 Sentence denotes On the other side, IFN is one of the most potent innate immune responses to prevent viral replication during the early phases of infection [110].
T159 27616-27831 Sentence denotes The activation of transcription through JAK/STAT signaling pathway by IFNs leads to the upregulation of several interferon stimulated genes which have the ability to rapidly kill viruses within infected cells [111].
T160 27832-28079 Sentence denotes Almost all viruses have developed strategies to combat the effects of type 1 and type 3 IFNs by blocking the IFN signaling pathway [112] and viral encoded factors able to antagonize the JAK/STAT pathway are crucial determinants of virulence [113].
T161 28080-28236 Sentence denotes In particular, Influenza A viruses disrupt JAK/STAT signaling by reducing the expression of the IFN receptor and by directly inhibiting IFN signaling [114].
T162 28237-28487 Sentence denotes As a consequence, JAK/STAT blockade generated by baricitinib certainly produces an impairment of IFN-mediated anti-viral response, with a potential facilitating effect on the progression of SARS-CoV2 infection at the moment not yet better quantified.
T163 28488-28744 Sentence denotes In conclusion, evidence of the possible use of baricitinib in the treatment of COVID-19 infection remains highly controversial and further studies are warranted to better clarify its potential role in the treatment of more serious cases of viral pneumonia.
T164 28746-28760 Sentence denotes 6 Conclusions
T165 28761-28899 Sentence denotes The COVID-19 epidemic represents a health emergency that is inevitably affecting the management of a complex disease such as RA [115,116].
T166 28900-29011 Sentence denotes As a chronic autoimmune inflammatory disorder, RA carries a higher infectious risk than the general population.
T167 29012-29244 Sentence denotes The use of synthetic and biologic disease-modifying drugs is associated with a potential further increase in the incidence of serious infections, but the poor control of RA disease activity is an even greater infectious risk factor.
T168 29245-29342 Sentence denotes Thus, RA patients should be encouraged to continue their treatment even during COVID-19 outbreak.
T169 29343-29532 Sentence denotes In our opinion, this strategy is reasonable as it aims to prevent disease flares that can contributes to increase patient burden, disability, poor quality of life, and healthcare use [117].
T170 29533-29790 Sentence denotes In addition, the discontinuation of ongoing treatments could lead to the need to introduce CS as bridging therapy, which may further increase the risk of viral infection, as well as being inappropriate for the management of SARS-CoV2 interstitial pneumonia.
T171 29791-30028 Sentence denotes Chloroquine and hydroxychloroquine are currently included in the treatment protocol for the management of COVID-19 infections and might be useful to prevent or mitigate the course of infection in patients with RA taking them as csDMARDs.
T172 30029-30320 Sentence denotes The use of IL-6 inhibitors as tocilizumab or sarilumab seems to be promising for the management of most critical cases of interstitial pneumonia complicated by CRS, but the identification of definite criteria to discriminate patients to be treated with these compounds is still under debate.
T173 30321-30554 Sentence denotes Finally, although baricitinib has the potential to affect SARS-CoV2 penetration into pulmonary epithelial cells, major concerns remain about the inhibition of IFNs activity which could be detrimental in the course of viral infection.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T7 47-56 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T8 394-403 Phenotype denotes dry cough http://purl.obolibrary.org/obo/HP_0031246
T9 405-410 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T10 412-419 Phenotype denotes dyspnea http://purl.obolibrary.org/obo/HP_0002094
T11 424-431 Phenotype denotes fatigue http://purl.obolibrary.org/obo/HP_0012378
T12 448-459 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T13 619-628 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T14 693-713 Phenotype denotes Respiratory Distress http://purl.obolibrary.org/obo/HP_0002098
T15 1928-1948 Phenotype denotes rheumatoid arthritis http://purl.obolibrary.org/obo/HP_0001370
T16 1950-1952 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T17 2154-2163 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T18 2285-2299 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T19 2747-2749 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T20 4054-4071 Phenotype denotes diabetes mellitus http://purl.obolibrary.org/obo/HP_0000819
T21 4075-4087 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T22 4621-4633 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T23 4635-4652 Phenotype denotes diabetes mellitus http://purl.obolibrary.org/obo/HP_0000819
T24 4667-4673 Phenotype denotes stroke http://purl.obolibrary.org/obo/HP_0001297
T25 5027-5053 Phenotype denotes Cytokines Release Syndrome http://purl.obolibrary.org/obo/HP_0033041
T26 5405-5410 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T27 5412-5430 Phenotype denotes hyperferritinaemia http://purl.obolibrary.org/obo/HP_0003281
T28 5736-5741 Phenotype denotes tumor http://purl.obolibrary.org/obo/HP_0002664
T29 5882-5896 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T30 6007-6009 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T31 6045-6047 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T32 6243-6252 Phenotype denotes arthritis http://purl.obolibrary.org/obo/HP_0001369
T33 6542-6544 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T34 6667-6669 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T35 6725-6734 Phenotype denotes arthritis http://purl.obolibrary.org/obo/HP_0001369
T36 6847-6849 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T37 7053-7055 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T38 7069-7071 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T39 7508-7528 Phenotype denotes autoimmune disorders http://purl.obolibrary.org/obo/HP_0002960
T40 7656-7658 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T41 8493-8495 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T42 8502-8519 Phenotype denotes Diabetes mellitus http://purl.obolibrary.org/obo/HP_0000819
T43 8521-8544 Phenotype denotes cardiovascular diseases http://purl.obolibrary.org/obo/HP_0001626
T44 8546-8559 Phenotype denotes renal failure http://purl.obolibrary.org/obo/HP_0000083
T45 8561-8586 Phenotype denotes interstitial lung disease http://purl.obolibrary.org/obo/HP_0006530
T46 8592-8629 Phenotype denotes chronic obstructive pulmonary disease http://purl.obolibrary.org/obo/HP_0006510
T47 8631-8635 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T48 8723-8725 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T49 8744-8746 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T50 9099-9101 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T51 9282-9284 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T52 9368-9370 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T53 9487-9504 Phenotype denotes severe infections http://purl.obolibrary.org/obo/HP_0032169
T54 9684-9686 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T55 9798-9800 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T56 9942-9944 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T57 10743-10766 Phenotype denotes diffuse alveolar damage http://purl.obolibrary.org/obo/HP_0033006
T58 12235-12240 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T59 12498-12500 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T60 12586-12588 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T61 13510-13512 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T62 14084-14106 Phenotype denotes respiratory infections http://purl.obolibrary.org/obo/HP_0011947
T63 14768-14792 Phenotype denotes opportunistic infections http://purl.obolibrary.org/obo/HP_0031690
T64 14840-14842 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T65 15254-15256 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T66 18539-18541 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T67 19029-19043 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T68 19161-19170 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T69 19346-19360 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T70 19631-19636 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T71 19822-19842 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T72 20209-20211 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T73 21462-21471 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T74 22758-22767 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T75 22824-22830 Phenotype denotes sepsis http://purl.obolibrary.org/obo/HP_0100806
T76 23249-23251 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T77 23256-23281 Phenotype denotes cytokine release syndrome http://purl.obolibrary.org/obo/HP_0033041
T78 23361-23370 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T79 23532-23541 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T80 23552-23571 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T81 24240-24249 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T82 24296-24315 Phenotype denotes Increasing ferritin http://purl.obolibrary.org/obo/HP_0003281
T83 26461-26463 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T84 26732-26741 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T85 27194-27196 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T86 28734-28743 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T87 28886-28888 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T88 28947-28949 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T89 29182-29184 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T90 29251-29253 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T91 29780-29789 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T92 30001-30003 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T93 30164-30173 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090

2_test

Id Subject Object Predicate Lexical cue
32205186-32015507-4826866 220-221 32015507 denotes 1
32205186-25172238-4826867 1761-1762 25172238 denotes 9
32205186-24800825-4826868 3974-3976 24800825 denotes 14
32205186-24290661-4826869 5349-5351 24290661 denotes 19
32205186-26836913-4826870 5534-5536 26836913 denotes 20
32205186-26096095-4826871 6427-6429 26096095 denotes 23
32205186-23266520-4826872 6430-6432 23266520 denotes 24
32205186-29259607-4826873 6546-6548 29259607 denotes 25
32205186-31470887-4826874 6671-6673 31470887 denotes 26
32205186-23192911-4826875 6810-6812 23192911 denotes 27
32205186-20675706-4826876 6816-6818 20675706 denotes 28
32205186-12355475-4826877 7209-7211 12355475 denotes 30
32205186-16984941-4826878 7408-7410 16984941 denotes 31
32205186-21288960-4826879 7951-7953 21288960 denotes 32
32205186-24095940-4826880 8497-8499 24095940 denotes 34
32205186-23192911-4826881 8727-8729 23192911 denotes 27
32205186-23813577-4826882 8730-8732 23813577 denotes 35
32205186-31396235-4826883 9416-9418 31396235 denotes 37
32205186-23192911-4826884 9593-9595 23192911 denotes 27
32205186-17870034-4826885 9596-9598 17870034 denotes 38
32205186-9251634-4826886 9698-9700 9251634 denotes 39
32205186-22393128-4826887 9710-9712 22393128 denotes 41
32205186-21884589-4826888 9866-9868 21884589 denotes 42
32205186-16195357-4826889 10518-10520 16195357 denotes 43
32205186-30917856-4826890 11307-11309 30917856 denotes 47
32205186-25896805-4826891 11992-11994 25896805 denotes 50
32205186-18668604-4826892 12638-12640 18668604 denotes 51
32205186-18260176-4826893 13186-13188 18260176 denotes 52
32205186-23192911-4826894 13632-13634 23192911 denotes 27
32205186-29180125-4826895 13635-13637 29180125 denotes 54
32205186-28298374-4826896 13677-13679 28298374 denotes 55
32205186-19022409-4826897 13718-13720 19022409 denotes 56
32205186-22796281-4826898 13724-13726 22796281 denotes 57
32205186-29592917-4826899 13730-13732 29592917 denotes 58
32205186-25975452-4826900 13905-13907 25975452 denotes 59
32205186-23800448-4826901 14057-14059 23800448 denotes 61
32205186-23256105-4826902 14468-14470 23256105 denotes 62
32205186-31733368-4826903 14891-14893 31733368 denotes 65
32205186-30219772-4826904 15439-15441 30219772 denotes 68
32205186-27113415-4826905 15651-15653 27113415 denotes 69
32205186-30183607-4826906 15947-15949 30183607 denotes 71
32205186-31692920-4826907 16192-16194 31692920 denotes 72
32205186-31520803-4826908 16195-16197 31520803 denotes 73
32205186-28250461-4826909 16454-16456 28250461 denotes 74
32205186-26868298-4826910 17410-17412 26868298 denotes 76
32205186-32020029-4826911 17869-17871 32020029 denotes 80
32205186-30938227-4826912 18258-18260 30938227 denotes 81
32205186-32034323-4826913 20213-20215 32034323 denotes 83
32205186-4306296-4826914 20314-20316 4306296 denotes 84
32205186-21550310-4826915 20568-20570 21550310 denotes 86
32205186-16115318-4826916 20819-20821 16115318 denotes 88
32205186-16439323-4826917 20831-20833 16439323 denotes 90
32205186-26584195-4826918 22937-22939 26584195 denotes 95
32205186-24800825-4826919 24722-24724 24800825 denotes 14
32205186-18490652-4826920 24911-24913 18490652 denotes 99
32205186-17532082-4826921 25125-25128 17532082 denotes 100
32205186-28240606-4826922 26067-26070 28240606 denotes 103
32205186-29753658-4826923 26286-26289 29753658 denotes 105
32205186-29545548-4826924 26759-26762 29545548 denotes 107
32205186-29649002-4826925 26763-26766 29649002 denotes 108
32205186-18049472-4826926 27610-27613 18049472 denotes 110
32205186-31059844-4826927 28890-28893 31059844 denotes 115
32205186-29037899-4826928 28894-28897 29037899 denotes 116
32205186-31639516-4826929 29527-29530 31639516 denotes 117