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PMC:7102591 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
3 0-8 Disease denotes COVID-19 MESH:C000657245
4 9-18 Disease denotes infection MESH:D007239
5 23-43 Disease denotes rheumatoid arthritis MESH:D001172
19 277-324 Species denotes severe acute respiratory syndrome coronaviruses Tax:694009
20 326-336 Species denotes SARS-CoV-2 Tax:2697049
21 1236-1244 Species denotes patients Tax:9606
22 94-120 Disease denotes new coronavirus infections MESH:C000657245
23 121-129 Disease denotes COVID-19 MESH:C000657245
24 470-478 Disease denotes COVID-19 MESH:C000657245
25 562-582 Disease denotes rheumatoid arthritis MESH:D001172
26 584-586 Disease denotes RA MESH:D001172
27 720-739 Disease denotes autoimmune diseases MESH:D001327
28 897-917 Disease denotes SARS-CoV-2 infection MESH:C000657245
29 1020-1028 Disease denotes COVID-19 MESH:C000657245
30 1156-1158 Disease denotes RA MESH:D001172
31 1233-1235 Disease denotes RA MESH:D001172
52 1366-1376 Species denotes SARS-CoV-2 Tax:2697049
53 1403-1416 Species denotes coronavirus 2 Tax:2697049
54 1572-1580 Species denotes SARS-CoV Tax:694009
55 1610-1620 Species denotes SARS-CoV-2 Tax:2697049
56 1787-1795 Species denotes patients Tax:9606
57 1391-1402 Species denotes respiratory Tax:12814
58 1294-1303 Disease denotes pneumonia MESH:D011014
59 1641-1650 Disease denotes dry cough MESH:D003371
60 1652-1657 Disease denotes fever MESH:D005334
61 1659-1666 Disease denotes dyspnea MESH:D004417
62 1671-1678 Disease denotes fatigue MESH:D005221
63 1695-1706 Disease denotes lymphopenia MESH:D008231
64 1778-1786 Disease denotes infected MESH:D007239
65 1866-1875 Disease denotes pneumonia MESH:D011014
66 1881-1896 Disease denotes alveolar damage MESH:D055370
67 1934-1969 Disease denotes Acute Respiratory Distress Syndrome MESH:D012128
68 1971-1975 Disease denotes ARDS MESH:D012128
69 1986-1991 Disease denotes death MESH:D003643
70 2158-2166 Disease denotes COVID-19 MESH:C000657245
71 2437-2443 Disease denotes deaths MESH:D003643
88 3441-3454 Gene denotes interleukin 6 Gene:3569
89 3456-3460 Gene denotes IL-6 Gene:3569
90 2569-2577 Species denotes patients Tax:9606
91 2768-2776 Species denotes patients Tax:9606
92 3260-3271 Chemical denotes Chloroquine MESH:D002738
93 3276-3294 Chemical denotes hydroxychloroquine MESH:D006886
94 2530-2538 Disease denotes COVID-19 MESH:C000657245
95 2561-2568 Disease denotes fragile MESH:D005600
96 3079-3099 Disease denotes SARS-CoV-2 infection MESH:C000657245
97 3175-3195 Disease denotes rheumatoid arthritis MESH:D001172
98 3197-3199 Disease denotes RA MESH:D001172
99 3250-3258 Disease denotes COVID-19 MESH:C000657245
100 3392-3410 Disease denotes COVID-19 pneumonia MESH:C000657245
101 3592-3603 Disease denotes lung damage MESH:D008171
102 3623-3627 Disease denotes ARDS MESH:D012128
103 3673-3691 Disease denotes SARS-CoV infection MESH:C000657245
108 3788-3796 Species denotes patients Tax:9606
109 3997-4005 Species denotes patients Tax:9606
110 3760-3768 Disease denotes COVID-19 MESH:C000657245
111 3994-3996 Disease denotes RA MESH:D001172
114 4179-4187 Disease denotes COVID-19 MESH:C000657245
115 4188-4197 Disease denotes infection MESH:D007239
139 4479-4510 Gene denotes angiotensin-converting enzyme 2 Gene:59272
140 4512-4516 Gene denotes ACE2 Gene:59272
141 4620-4624 Gene denotes ACE2 Gene:59272
142 4894-4898 Gene denotes ACE2 Gene:59272
143 4953-4967 Gene denotes angiotensin II Gene:183
144 4990-4993 Gene denotes ACE Gene:1636
145 5202-5206 Gene denotes ACE2 Gene:59272
146 5824-5828 Gene denotes ACE2 Gene:59272
147 4198-4211 Species denotes Coronaviruses Tax:11118
148 4576-4585 Species denotes SARS-CoV2 Tax:2697049
149 4358-4366 Disease denotes COVID-19 MESH:C000657245
150 4367-4376 Disease denotes infection MESH:D007239
151 4820-4835 Disease denotes viral infection MESH:D001102
152 4842-4862 Disease denotes SARS-CoV-2 infection MESH:C000657245
153 5167-5178 Disease denotes lung damage MESH:D008171
154 5301-5318 Disease denotes diabetes mellitus MESH:D003920
155 5322-5334 Disease denotes hypertension MESH:D006973
156 5430-5439 Disease denotes infection MESH:D007239
157 5460-5468 Disease denotes COVID-19 MESH:C000657245
158 5796-5816 Disease denotes SARS-CoV-2 infection MESH:C000657245
159 5868-5880 Disease denotes hypertension MESH:D006973
160 5882-5899 Disease denotes diabetes mellitus MESH:D003920
161 5905-5920 Disease denotes cerebral stroke MESH:D020521
188 6935-6949 Gene denotes interleukin-1β Gene:3553
189 6951-6956 Gene denotes IL-1β Gene:3552
190 6959-6963 Gene denotes IL-2 Gene:3558
191 6965-6969 Gene denotes IL-6 Gene:3569
192 6971-6975 Gene denotes IL-7 Gene:3574
193 6977-6981 Gene denotes IL-8 Gene:3576
194 6983-7006 Gene denotes tumor necrosis factor-α Gene:7124
195 7008-7011 Gene denotes TNF Gene:7124
196 7030-7053 Gene denotes CXC-chemokine ligand 10 Gene:3627
197 7055-7061 Gene denotes CXCL10 Gene:3627
198 7067-7088 Gene denotes CC-chemokine ligand 2 Gene:6347
199 7090-7094 Gene denotes CCL2 Gene:6347
200 6771-6779 Species denotes patients Tax:9606
201 6178-6182 Disease denotes ARDS MESH:D012128
202 6347-6392 Disease denotes secondary haemophagocytic lymphohistiocytosis MESH:D060085
203 6441-6467 Disease denotes hyperinflammatory syndrome MESH:D061325
204 6505-6546 Disease denotes hypercytokinaemia with multiorgan failure MESH:D009102
205 6575-6591 Disease denotes viral infections MESH:D001102
206 6652-6657 Disease denotes fever MESH:D005334
207 6659-6692 Disease denotes hyperferritinaemia and cytopenias MESH:D006402
208 6698-6719 Disease denotes pulmonary involvement MESH:D008171
209 6731-6735 Disease denotes ARDS MESH:D012128
210 6854-6862 Disease denotes COVID-19 MESH:C000657245
211 6863-6873 Disease denotes infections MESH:D007239
212 7186-7194 Disease denotes COVID-19 MESH:C000657245
213 7195-7204 Disease denotes infection MESH:D007239
217 7257-7265 Species denotes patients Tax:9606
218 7225-7240 Disease denotes viral infection MESH:D001102
219 7254-7256 Disease denotes RA MESH:D001172
252 7857-7868 Species denotes coronavirus Tax:11118
253 7939-7947 Species denotes patients Tax:9606
254 8097-8105 Species denotes patients Tax:9606
255 8275-8283 Species denotes patients Tax:9606
256 8319-8327 Species denotes patients Tax:9606
257 8517-8525 Species denotes patients Tax:9606
258 8906-8914 Species denotes patients Tax:9606
259 9155-9165 Species denotes outpatient Tax:9606
260 9331-9339 Species denotes patients Tax:9606
261 7737-7748 Species denotes respiratory Tax:12814
262 7292-7294 Disease denotes RA MESH:D001172
263 7299-7318 Disease denotes infectious diseases MESH:D003141
264 7490-7499 Disease denotes arthritis MESH:D001168
265 7649-7658 Disease denotes infection MESH:D007239
266 7749-7765 Disease denotes viral infections MESH:D001102
267 7789-7791 Disease denotes RA MESH:D001172
268 7914-7916 Disease denotes RA MESH:D001172
269 7972-7981 Disease denotes arthritis MESH:D001168
270 7983-7993 Disease denotes infections MESH:D007239
271 8094-8096 Disease denotes RA MESH:D001172
272 8143-8152 Disease denotes infection MESH:D007239
273 8300-8302 Disease denotes RA MESH:D001172
274 8316-8318 Disease denotes RA MESH:D001172
275 8444-8454 Disease denotes infections MESH:D007239
276 8531-8557 Disease denotes inflammatory polyarthritis MESH:D001168
277 8613-8622 Disease denotes infection MESH:D007239
278 8755-8775 Disease denotes autoimmune disorders MESH:D001327
279 8903-8905 Disease denotes RA MESH:D001172
280 9049-9059 Disease denotes infections MESH:D007239
281 9166-9176 Disease denotes infections MESH:D007239
282 9291-9301 Disease denotes infections MESH:D007239
283 9584-9608 Disease denotes infectious complications MESH:D011251
293 9740-9742 Disease denotes RA MESH:D001172
294 9749-9766 Disease denotes Diabetes mellitus MESH:D003920
295 9768-9791 Disease denotes cardiovascular diseases MESH:D002318
296 9793-9806 Disease denotes renal failure MESH:D051437
297 9808-9833 Disease denotes interstitial lung disease MESH:D017563
298 9839-9876 Disease denotes chronic obstructive pulmonary disease MESH:D029424
299 9878-9882 Disease denotes COPD MESH:D029424
300 9956-9966 Disease denotes infections MESH:D007239
301 9970-9972 Disease denotes RA MESH:D001172
304 9991-9993 Disease denotes RA MESH:D001172
305 10021-10031 Disease denotes infections MESH:D007239
308 10179-10197 Disease denotes rheumatic diseases MESH:D012216
309 10201-10217 Disease denotes viral infections MESH:D001102
333 11070-11072 Gene denotes CS Gene:1431
334 11445-11447 Gene denotes CS Gene:1431
335 11211-11213 Gene denotes CS Gene:1431
336 10889-10891 Gene denotes CS Gene:1431
337 10560-10562 Gene denotes CS Gene:1431
338 10326-10328 Gene denotes CS Gene:1431
339 10934-10942 Species denotes patients Tax:9606
340 11048-11056 Species denotes patients Tax:9606
341 11192-11200 Species denotes patients Tax:9606
342 11428-11435 Species denotes patient Tax:9606
343 10346-10348 Disease denotes RA MESH:D001172
344 10529-10531 Disease denotes RA MESH:D001172
345 10595-10607 Disease denotes inflammation MESH:D007249
346 10615-10617 Disease denotes RA MESH:D001172
347 10741-10751 Disease denotes infections MESH:D007239
348 10829-10838 Disease denotes infection MESH:D007239
349 10917-10927 Disease denotes infections MESH:D007239
350 10931-10933 Disease denotes RA MESH:D001172
351 11031-11041 Disease denotes infections MESH:D007239
352 11045-11047 Disease denotes RA MESH:D001172
353 11189-11191 Disease denotes RA MESH:D001172
354 11256-11272 Disease denotes viral infections MESH:D001102
355 11364-11381 Disease denotes Zoster infections MESH:D006562
371 12103-12105 Gene denotes CS Gene:1431
372 11479-11481 Gene denotes CS Gene:1431
373 11828-11830 Gene denotes CS Gene:1431
374 11887-11896 Species denotes MERS)-CoV Tax:1335626
375 11906-11914 Species denotes SARS-CoV Tax:694009
376 11682-11693 Species denotes respiratory Tax:12814
377 12254-12263 Species denotes influenza Tax:11309
378 11658-11674 Disease denotes viral infections MESH:D001102
379 11729-11740 Disease denotes lung damage MESH:D008171
380 11759-11763 Disease denotes ARDS MESH:D012128
381 11853-11885 Disease denotes Middle East respiratory syndrome MESH:D018352
382 11968-11985 Disease denotes lung inflammation MESH:D011014
383 11998-12013 Disease denotes alveolar damage MESH:D055370
384 12140-12149 Disease denotes infection MESH:D007239
385 12283-12292 Disease denotes mortality MESH:D003643
399 12835-12837 Gene denotes CS Gene:1431
400 12550-12552 Gene denotes CS Gene:1431
401 13021-13023 Gene denotes CS Gene:1431
402 12718-12720 Gene denotes CS Gene:1431
403 12531-12539 Species denotes patients Tax:9606
404 12651-12659 Species denotes patients Tax:9606
405 12784-12792 Species denotes patients Tax:9606
406 12372-12401 Disease denotes bacterial or fungal infection MESH:D001424
407 12603-12607 Disease denotes ARDS MESH:D012128
408 12798-12806 Disease denotes COVID-19 MESH:C000657245
409 12807-12816 Disease denotes infection MESH:D007239
410 12975-12983 Disease denotes COVID-19 MESH:C000657245
411 12984-12993 Disease denotes infection MESH:D007239
424 13206-13210 Gene denotes ACE2 Gene:302668
425 13233-13237 Species denotes rats Tax:10116
426 13371-13379 Species denotes patients Tax:9606
427 13143-13152 Chemical denotes Ibuprofen MESH:D007052
428 13426-13439 Chemical denotes acetaminophen MESH:D000082
429 13102-13118 Disease denotes viral infections MESH:D001102
430 13224-13232 Disease denotes diabetic MESH:D003920
431 13341-13349 Disease denotes COVID-19 MESH:C000657245
432 13350-13359 Disease denotes infection MESH:D007239
433 13482-13492 Disease denotes fever rise MESH:D005334
434 13500-13508 Disease denotes COVID-19 MESH:C000657245
435 13573-13582 Disease denotes infection MESH:D007239
449 14576-14579 Gene denotes MTX Gene:4580
450 13653-13661 Species denotes patients Tax:9606
451 14224-14232 Species denotes patients Tax:9606
452 14557-14565 Species denotes patients Tax:9606
453 14322-14334 Chemical denotes methotrexate MESH:D008727
454 14376-14394 Chemical denotes hydroxychloroquine MESH:D006886
455 13745-13747 Disease denotes RA MESH:D001172
456 13833-13835 Disease denotes RA MESH:D001172
457 13975-13984 Disease denotes infection MESH:D007239
458 14112-14121 Disease denotes infection MESH:D007239
459 14308-14317 Disease denotes infection MESH:D007239
460 14544-14553 Disease denotes infection MESH:D007239
461 14686-14695 Disease denotes infection MESH:D007239
463 14715-14722 Chemical denotes bDMARDs
469 14760-14768 Species denotes patients Tax:9606
470 14782-14789 Chemical denotes bDMARDs
471 15108-15115 Chemical denotes bDMARDs
472 14735-14744 Disease denotes infection MESH:D007239
473 14757-14759 Disease denotes RA MESH:D001172
483 15790-15793 Gene denotes TNF Gene:7124
484 15474-15482 Species denotes patients Tax:9606
485 15802-15810 Species denotes patients Tax:9606
486 15412-15421 Species denotes influenza Tax:11309
487 15515-15524 Species denotes influenza Tax:11309
488 15860-15869 Species denotes influenza Tax:11309
489 15331-15353 Disease denotes respiratory infections MESH:D012141
490 15427-15437 Disease denotes infections MESH:D007239
491 15914-15919 Disease denotes death MESH:D003643
493 15974-15982 Disease denotes tsDMARDs
512 17250-17255 Gene denotes JAK-1 Gene:3716
513 16090-16098 Species denotes patients Tax:9606
514 16395-16402 Species denotes patient Tax:9606
515 16504-16512 Species denotes patients Tax:9606
516 16671-16678 Species denotes patient Tax:9606
517 16795-16803 Species denotes patients Tax:9606
518 16173-16184 Chemical denotes tofacitinib MESH:C479163
519 16189-16200 Chemical denotes baricitinib MESH:C000596027
520 16304-16315 Chemical denotes tofacitinib MESH:C479163
521 16618-16629 Chemical denotes baricitinib MESH:C000596027
522 16814-16825 Chemical denotes tofacitinib MESH:C479163
523 17019-17029 Chemical denotes prednisone MESH:D011241
524 17277-17289 Chemical denotes upadacitinib MESH:C000613732
525 17294-17304 Chemical denotes filgotinib MESH:C584571
526 16015-16039 Disease denotes opportunistic infections MESH:D009894
527 16087-16089 Disease denotes RA MESH:D001172
528 16277-16287 Disease denotes infections MESH:D007239
529 16501-16503 Disease denotes RA MESH:D001172
531 17754-17782 Disease denotes respiratory virus infections
533 17832-17840 Disease denotes COVID-19 MESH:C000657245
557 18402-18412 Species denotes SARS-CoV-2 Tax:2697049
558 18423-18438 Species denotes Betacoronavirus Tax:694002
559 18477-18485 Species denotes SARS-CoV Tax:694009
560 18490-18498 Species denotes MERS-Cov Tax:1335626
561 19371-19382 Species denotes coronavirus Tax:11118
562 19447-19456 Species denotes SARS-CoV2 Tax:2697049
563 19485-19490 Species denotes human Tax:9606
564 19329-19334 Species denotes human Tax:9606
565 18581-18590 Chemical denotes ribavirin MESH:D012254
566 18596-18615 Chemical denotes lopinavir-ritonavir MESH:C558899
567 18711-18730 Chemical denotes lopinavir-ritonavir MESH:C558899
568 18813-18823 Chemical denotes remdesivir MESH:C000606551
569 18828-18837 Chemical denotes adenosine MESH:D000241
570 19135-19154 Chemical denotes lopinavir-ritonavir MESH:C558899
571 19159-19169 Chemical denotes remdesevir
572 17964-17979 Disease denotes CoV-2 infection MESH:C000657245
573 18020-18028 Disease denotes COVID-19 MESH:C000657245
574 18225-18233 Disease denotes COVID-19 MESH:C000657245
575 18334-18350 Disease denotes viral infections MESH:D001102
576 18647-18655 Disease denotes COVID-19 MESH:C000657245
577 18903-18918 Disease denotes virus infection MESH:D001102
578 19094-19114 Disease denotes SARS-CoV-2 infection MESH:C000657245
579 19267-19275 Disease denotes COVID-19 MESH:C000657245
595 20219-20224 Gene denotes ACE 2 Gene:59272
596 20247-20251 Gene denotes IL-6 Gene:3569
597 20517-20520 Gene denotes NAK Gene:29110
598 20847-20851 Gene denotes ACE2 Gene:59272
599 20678-20681 Gene denotes TNF Gene:7124
600 20356-20364 Species denotes patients Tax:9606
601 20313-20317 Disease denotes ARDS MESH:D012128
602 20408-20417 Disease denotes pneumonia MESH:D011014
603 20630-20634 Disease denotes ARDS MESH:D012128
604 20653-20677 Disease denotes secondary HZV infections MESH:D060085
605 20762-20777 Disease denotes viral infection MESH:D001102
606 20878-20883 Disease denotes fever MESH:D005334
607 20928-20943 Disease denotes viral infection MESH:D001102
608 20954-20963 Disease denotes mortality MESH:D003643
609 20999-21015 Disease denotes fungal infection MESH:D009181
612 19992-20000 Disease denotes COVID-19 MESH:C000657245
613 20001-20010 Disease denotes infection MESH:D007239
620 21016-21020 Gene denotes ACE2 Gene:59272
621 21023-21054 Gene denotes angiotensin converting enzyme 2 Gene:59272
622 21100-21103 Gene denotes NAK Gene:29110
623 21106-21128 Gene denotes numb-associated kinase Gene:29110
624 21056-21060 Disease denotes ARDS MESH:D012128
625 21063-21098 Disease denotes acute respiratory distress syndrome MESH:D012128
629 19786-19788 Disease denotes RA MESH:D001172
630 19834-19842 Disease denotes COVID-19 MESH:C000657245
631 19920-19929 Disease denotes infection MESH:D007239
633 21228-21258 Chemical denotes Chloroquine/hydroxychloroquine
640 21683-21699 Species denotes SARS coronavirus Tax:694009
641 21259-21270 Chemical denotes Chloroquine MESH:D002738
642 21275-21293 Chemical denotes hydroxychloroquine MESH:D006886
643 21480-21491 Chemical denotes chloroquine MESH:D002738
644 21414-21445 Disease denotes immuno-rheumatological diseases MESH:D000163
645 21456-21458 Disease denotes RA MESH:D001172
657 22058-22063 Gene denotes ACE 2 Gene:59272
658 22561-22569 Species denotes patients Tax:9606
659 21863-21874 Chemical denotes chloroquine MESH:D002738
660 22282-22293 Chemical denotes chloroquine MESH:D002738
661 22593-22604 Chemical denotes chloroquine MESH:D002738
662 22846-22864 Chemical denotes hydroxychloroquine MESH:D006886
663 22918-22929 Chemical denotes chloroquine MESH:D002738
664 22244-22262 Disease denotes SARS CoV infection MESH:C000657245
665 22433-22441 Disease denotes COVID-19 MESH:C000657245
666 22709-22718 Disease denotes pneumonia MESH:D011014
667 23155-23175 Disease denotes SARS-CoV-2 infection MESH:C000657245
670 23188-23192 Gene denotes IL-6 Gene:3569
671 23197-23201 Gene denotes IL-1 Gene:3552
703 23832-23836 Gene denotes IL-6 Gene:3569
704 23841-23845 Gene denotes IL-1 Gene:3552
705 24043-24047 Gene denotes IL-1 Gene:3552
706 24359-24362 Gene denotes CRP Gene:1401
707 24631-24635 Gene denotes IL-6 Gene:3569
708 24942-24946 Gene denotes IL-6 Gene:3569
709 23974-23983 Species denotes SARS-CoV2 Tax:2697049
710 24117-24125 Species denotes patients Tax:9606
711 24223-24231 Species denotes patients Tax:9606
712 24407-24415 Species denotes patients Tax:9606
713 24585-24593 Species denotes patients Tax:9606
714 24765-24773 Species denotes patients Tax:9606
715 24278-24289 Chemical denotes tocilizumab MESH:C502936
716 24325-24331 Chemical denotes oxygen MESH:D010100
717 24443-24454 Chemical denotes tocilizumab MESH:C502936
718 24957-24966 Chemical denotes sarilumab MESH:C000592401
719 23233-23237 Disease denotes ARDS MESH:D012128
720 23271-23279 Disease denotes COVID-19 MESH:C000657245
721 23280-23289 Disease denotes infection MESH:D007239
722 23406-23417 Disease denotes lung injury MESH:D055370
723 23673-23689 Disease denotes viral infections MESH:D001102
724 23812-23820 Disease denotes COVID-19 MESH:C000657245
725 24005-24014 Disease denotes pneumonia MESH:D011014
726 24071-24077 Disease denotes sepsis MESH:D018805
727 24251-24259 Disease denotes COVID-19 MESH:C000657245
728 24496-24498 Disease denotes RA MESH:D001172
729 24599-24617 Disease denotes COVID-19 pneumonia MESH:C000657245
730 24779-24788 Disease denotes pneumonia MESH:D011014
731 24799-24818 Disease denotes respiratory failure MESH:D012131
732 24833-24842 Disease denotes mortality MESH:D003643
733 24873-24883 Disease denotes TOCIVID-19 MESH:C000657245
746 25268-25271 Gene denotes CD4 Gene:920
747 25276-25279 Gene denotes CD8 Gene:925
748 25360-25364 Gene denotes IL-6 Gene:3569
749 25182-25190 Species denotes patients Tax:9606
750 25505-25513 Species denotes patients Tax:9606
751 25700-25708 Species denotes patients Tax:9606
752 25105-25113 Disease denotes COVID-19 MESH:C000657245
753 25114-25123 Disease denotes infection MESH:D007239
754 25224-25235 Disease denotes lung injury MESH:D055370
755 25476-25496 Disease denotes critically pneumonia MESH:D016638
756 25514-25522 Disease denotes infected MESH:D007239
757 25528-25536 Disease denotes COVID-19 MESH:C000657245
759 25759-25762 Gene denotes TNF Gene:7124
764 25857-25861 Gene denotes ACE2 Gene:59272
765 25915-25920 Gene denotes renin Gene:5972
766 25799-25817 Disease denotes SARS-CoV infection MESH:C000657245
767 25956-25967 Disease denotes lung injury MESH:D055370
778 26028-26051 Gene denotes TNF-α-converting enzyme Gene:6868
779 26053-26057 Gene denotes TACE Gene:6868
780 26085-26089 Gene denotes ACE2 Gene:59272
781 26214-26218 Gene denotes TNFα Gene:7124
782 26270-26273 Gene denotes TNF Gene:7124
783 26319-26328 Species denotes SARS-CoV2 Tax:2697049
784 26410-26420 Chemical denotes adalimumab MESH:D000068879
785 26329-26338 Disease denotes infection MESH:D007239
786 26424-26432 Disease denotes COVID-19 MESH:C000657245
787 26433-26442 Disease denotes infection MESH:D007239
829 26759-26781 Gene denotes numb-associated kinase Gene:29110
830 26783-26786 Gene denotes NAK Gene:29110
831 26804-26835 Gene denotes AP2-associated protein kinase 1 Gene:22848
832 26837-26841 Gene denotes AAK1 Gene:22848
833 26847-26873 Gene denotes cyclin G-associated kinase Gene:2580
834 26875-26878 Gene denotes GAK Gene:2580
835 26901-26905 Gene denotes AAK1 Gene:22848
836 27023-27027 Gene denotes AAK1 Gene:22848
837 27073-27077 Gene denotes AAK1 Gene:22848
838 27384-27387 Gene denotes NAK Gene:29110
839 27612-27616 Gene denotes AAK1 Gene:22848
840 27621-27624 Gene denotes GAK Gene:2580
841 27774-27785 Gene denotes JAK 1 and 2 Gene:3716
842 27898-27902 Gene denotes IL-6 Gene:3569
843 28319-28323 Gene denotes AAK1 Gene:22848
844 27907-27923 Gene denotes interferon gamma Gene:3458
845 26596-26606 Species denotes SARS-CoV-2 Tax:2697049
846 27254-27266 Species denotes Dengue virus Tax:12637
847 27268-27279 Species denotes Ebola virus Tax:205488
848 27285-27312 Species denotes respiratory syncytial virus Tax:12814
849 27520-27527 Species denotes patient Tax:9606
850 27137-27146 Chemical denotes erlotinib MESH:D000069347
851 27148-27157 Chemical denotes sunitinib MESH:D000077210
852 27159-27170 Chemical denotes ruxolitinib MESH:C540383
853 27176-27186 Chemical denotes fedratinib MESH:C528327
854 27569-27580 Chemical denotes baricitinib MESH:C000596027
855 27787-27798 Chemical denotes baricitinib MESH:C000596027
856 28052-28063 Chemical denotes baricitinib MESH:C000596027
857 28216-28235 Chemical denotes lopinavir/ritonavir MESH:C558899
858 28240-28250 Chemical denotes remdesivir MESH:C000606551
859 28273-28284 Chemical denotes tofacitinib MESH:C479163
860 28453-28465 Chemical denotes upadacitinib MESH:C000613732
861 28469-28479 Chemical denotes filgotinib MESH:C584571
862 28685-28696 Chemical denotes ruxolitinib MESH:C540383
863 27232-27241 Disease denotes infection MESH:D007239
864 27708-27710 Disease denotes RA MESH:D001172
865 27979-27988 Disease denotes pneumonia MESH:D011014
866 27996-28004 Disease denotes COVID-19 MESH:C000657245
867 28441-28443 Disease denotes RA MESH:D001172
868 28496-28517 Disease denotes coronavirus infection MESH:D018352
869 28650-28658 Disease denotes COVID-19 MESH:C000657245
876 29674-29683 Species denotes SARS-CoV2 Tax:2697049
877 29342-29351 Species denotes Influenza Tax:11309
878 29533-29544 Chemical denotes baricitinib MESH:C000596027
879 28846-28855 Disease denotes infection MESH:D007239
880 29057-29065 Disease denotes infected MESH:D007239
881 29684-29693 Disease denotes infection MESH:D007239
886 29782-29793 Chemical denotes baricitinib MESH:C000596027
887 29814-29822 Disease denotes COVID-19 MESH:C000657245
888 29823-29832 Disease denotes infection MESH:D007239
889 29975-29990 Disease denotes viral pneumonia
904 30871-30873 Gene denotes CS Gene:1431
905 30501-30509 Species denotes patients Tax:9606
906 30704-30711 Species denotes patient Tax:9606
907 31004-31013 Species denotes SARS-CoV2 Tax:2697049
908 30012-30020 Disease denotes COVID-19 MESH:C000657245
909 30133-30135 Disease denotes RA MESH:D001172
910 30160-30192 Disease denotes autoimmune inflammatory disorder MESH:D001327
911 30194-30196 Disease denotes RA MESH:D001172
912 30393-30403 Disease denotes infections MESH:D007239
913 30429-30431 Disease denotes RA MESH:D001172
914 30498-30500 Disease denotes RA MESH:D001172
915 30571-30579 Disease denotes COVID-19 MESH:C000657245
916 30934-30949 Disease denotes viral infection MESH:D001102
917 31027-31036 Disease denotes pneumonia MESH:D011014
933 31287-31291 Gene denotes IL-6 Gene:3569
934 31234-31242 Species denotes patients Tax:9606
935 31501-31509 Species denotes patients Tax:9606
936 31626-31635 Species denotes SARS-CoV2 Tax:2697049
937 31038-31049 Chemical denotes Chloroquine MESH:D002738
938 31054-31072 Chemical denotes hydroxychloroquine MESH:D006886
939 31306-31317 Chemical denotes tocilizumab MESH:C502936
940 31321-31330 Chemical denotes sarilumab MESH:C000592401
941 31586-31597 Chemical denotes baricitinib MESH:C000596027
942 31144-31152 Disease denotes COVID-19 MESH:C000657245
943 31153-31163 Disease denotes infections MESH:D007239
944 31221-31230 Disease denotes infection MESH:D007239
945 31248-31250 Disease denotes RA MESH:D001172
946 31411-31420 Disease denotes pneumonia MESH:D011014
947 31785-31800 Disease denotes viral infection MESH:D001102

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 695-708 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T2 1547-1557 Body_part denotes nucleotide http://purl.org/sig/ont/fma/fma82740
T3 1881-1889 Body_part denotes alveolar http://purl.org/sig/ont/fma/fma264783
T4 2659-2663 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T5 3025-3029 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T6 3441-3454 Body_part denotes interleukin 6 http://purl.org/sig/ont/fma/fma264829
T7 3441-3452 Body_part denotes interleukin http://purl.org/sig/ont/fma/fma86578
T8 3532-3540 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T9 3592-3596 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T10 4274-4277 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T11 4278-4284 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T12 4550-4562 Body_part denotes cell-surface http://purl.org/sig/ont/fma/fma67653
T13 4550-4554 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T14 4601-4613 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T15 4646-4653 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T16 4667-4672 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T17 4680-4686 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T18 4688-4693 Body_part denotes heart http://purl.org/sig/ont/fma/fma7088
T19 4695-4717 Body_part denotes gastrointestinal tract http://purl.org/sig/ont/fma/fma71132
T20 4719-4732 Body_part denotes blood vessels http://purl.org/sig/ont/fma/fma63183
T21 4719-4724 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T22 4752-4756 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T23 4761-4786 Body_part denotes alveolar epithelial cells http://purl.org/sig/ont/fma/fma62499
T24 4781-4786 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T25 5167-5171 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T26 5970-5973 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T27 5974-5980 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T28 6002-6011 Body_part denotes cytoplasm http://purl.org/sig/ont/fma/fma66835
T29 6021-6024 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T30 6150-6156 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T31 6239-6248 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T32 6253-6263 Body_part denotes chemokines http://purl.org/sig/ont/fma/fma241981
T33 6274-6283 Body_part denotes Cytokines http://purl.org/sig/ont/fma/fma84050
T34 6788-6796 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T35 6924-6933 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T36 6935-6948 Body_part denotes interleukin-1 http://purl.org/sig/ont/fma/fma86583
T37 6951-6955 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T38 6959-6963 Body_part denotes IL-2 http://purl.org/sig/ont/fma/fma84051
T39 7018-7028 Body_part denotes chemokines http://purl.org/sig/ont/fma/fma241981
T40 7030-7043 Body_part denotes CXC-chemokine http://purl.org/sig/ont/fma/fma241985
T41 7034-7043 Body_part denotes chemokine http://purl.org/sig/ont/fma/fma241981
T42 7067-7079 Body_part denotes CC-chemokine http://purl.org/sig/ont/fma/fma241983
T43 7129-7137 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T44 7398-7402 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T45 7553-7559 Body_part denotes joints http://purl.org/sig/ont/fma/fma73023
T46 8088-8092 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T47 8726-8739 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T48 9821-9825 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T49 10326-10328 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T50 10560-10562 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T51 10889-10891 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T52 11070-11072 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T53 11211-11213 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T54 11445-11447 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T55 11479-11481 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T56 11493-11497 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T57 11586-11590 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T58 11682-11699 Body_part denotes respiratory tract http://purl.org/sig/ont/fma/fma265130
T59 11729-11733 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T60 11828-11830 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T61 11968-11972 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T62 11998-12006 Body_part denotes alveolar http://purl.org/sig/ont/fma/fma264783
T63 12103-12105 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T64 12550-12552 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T65 12718-12720 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T66 12835-12837 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T67 13021-13023 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T68 17581-17585 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T69 19014-19017 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T70 19498-19503 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T71 20065-20074 Body_part denotes endosomal http://purl.org/sig/ont/fma/fma67180
T72 20097-20101 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T73 20276-20284 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T74 20500-20504 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T75 20593-20601 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T76 20738-20742 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T77 21899-21908 Body_part denotes endosomal http://purl.org/sig/ont/fma/fma67180
T78 21931-21935 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T79 22655-22659 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T80 23197-23201 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T81 23406-23410 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T82 23490-23499 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T83 23559-23570 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863
T84 23595-23600 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T85 23719-23736 Body_part denotes cytotoxic T cells http://purl.org/sig/ont/fma/fma70573
T86 23731-23736 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T87 23841-23845 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T88 24043-24047 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T89 24374-24385 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863
T90 24503-24511 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T91 25224-25228 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T92 25280-25293 Body_part denotes T-lymphocytes http://purl.org/sig/ont/fma/fma62870
T93 25379-25384 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T94 25573-25584 Body_part denotes erythrocyte http://purl.org/sig/ont/fma/fma62845
T95 25618-25626 Body_part denotes platelet http://purl.org/sig/ont/fma/fma62851
T96 25956-25960 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T97 26000-26007 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T98 26152-26156 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T99 26358-26363 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T100 26623-26628 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T101 26710-26718 Body_part denotes clathrin http://purl.org/sig/ont/fma/fma62262
T102 26819-26826 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T103 26944-26948 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T104 26949-26954 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T105 27245-27250 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T106 27632-27638 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T107 28590-28598 Body_part denotes clathrin http://purl.org/sig/ont/fma/fma62262
T108 29066-29071 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T109 30871-30873 Body_part denotes CS http://purl.org/sig/ont/fma/fma284995
T110 31663-31679 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T111 31674-31679 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 695-708 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T2 2659-2663 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T3 3025-3029 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T4 3592-3596 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T5 4680-4686 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T6 4688-4693 Body_part denotes heart http://purl.obolibrary.org/obo/UBERON_0000948
T7 4719-4732 Body_part denotes blood vessels http://purl.obolibrary.org/obo/UBERON_0001981
T8 4719-4724 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T9 4725-4732 Body_part denotes vessels http://purl.obolibrary.org/obo/UBERON_0000055
T10 4752-4756 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T11 5167-5171 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T12 7398-7402 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T13 8088-8092 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T14 8726-8739 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T15 9821-9825 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T16 11493-11497 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T17 11586-11590 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T18 11682-11699 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T19 11729-11733 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T20 11968-11972 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T21 22655-22659 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T22 23406-23410 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T23 25224-25228 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T24 25379-25384 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T25 25915-25939 Body_part denotes renin-angiotensin system http://purl.obolibrary.org/obo/UBERON_0018229
T26 25956-25960 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T27 26358-26363 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T28 26944-26948 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid_AGAC

Id Subject Object Predicate Lexical cue
p51540s9 4876-4890 NegReg denotes downregulation
p51540s11 4894-4898 Protein denotes ACE2
p51540s12 4899-4909 MPA denotes expression
p51540s17 4929-4938 PosReg denotes excessive
p51540s18 4939-4949 MPA denotes production
p51540s21 4965-4967 MPA denotes II
p51542s9 5111-5123 MPA denotes permeability
p51590s23 13279-13287 PosReg denotes increase
p51595s16 14279-14286 NegReg denotes reduced
p51644s32 22010-22032 MPA denotes terminal glycosylation
p51645s8 22138-22155 MPA denotes -receptor binding
p51651s48 23427-23437 CPA denotes to multior
p51653s23 23769-23778 NegReg denotes decreased
p51653s25 23785-23794 CPA denotes clearance
p51664s14 25837-25851 NegReg denotes a downregulati
p51664s17 25857-25867 MPA denotes ACE2 expre
p51664s21 25886-25895 PosReg denotes an increa
p51664s22 25889-25897 MPA denotes increase
p51685s7 29370-29388 Pathway denotes JAK/STAT signaling
p51685s12 29392-29400 NegReg denotes reducing
p51685s14 29405-29415 MPA denotes expression
p51685s22 29452-29462 NegReg denotes inhibiting
p51685s23 29463-29476 Pathway denotes IFN signaling
p51686s18 29585-29613 MPA denotes mediated anti-viral response
p51695s23 30913-30921 PosReg denotes increase

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 0-8 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T2 9-18 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T3 23-43 Disease denotes rheumatoid arthritis http://purl.obolibrary.org/obo/MONDO_0008383
T4 34-43 Disease denotes arthritis http://purl.obolibrary.org/obo/MONDO_0005578
T5 110-120 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T6 121-129 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T7 277-310 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T8 326-334 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T9 470-478 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T10 562-582 Disease denotes rheumatoid arthritis http://purl.obolibrary.org/obo/MONDO_0008383
T11 573-582 Disease denotes arthritis http://purl.obolibrary.org/obo/MONDO_0005578
T12 584-586 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T14 595-605 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T15 720-739 Disease denotes autoimmune diseases http://purl.obolibrary.org/obo/MONDO_0007179
T16 897-905 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T17 908-917 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T18 1020-1028 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T19 1156-1158 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T21 1233-1235 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T23 1294-1303 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T24 1366-1374 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T25 1572-1580 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T26 1610-1618 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T27 1695-1706 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T28 1866-1875 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T29 1934-1969 Disease denotes Acute Respiratory Distress Syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T30 1940-1969 Disease denotes Respiratory Distress Syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T31 1971-1975 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T32 2158-2166 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T33 2530-2538 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T34 2832-2842 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T35 3079-3087 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T36 3090-3099 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T37 3175-3195 Disease denotes rheumatoid arthritis http://purl.obolibrary.org/obo/MONDO_0008383
T38 3186-3195 Disease denotes arthritis http://purl.obolibrary.org/obo/MONDO_0005578
T39 3197-3199 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T41 3250-3258 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T42 3392-3400 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T43 3401-3410 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T44 3623-3627 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T45 3673-3691 Disease denotes SARS-CoV infection http://purl.obolibrary.org/obo/MONDO_0005091
T46 3682-3691 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T47 3760-3768 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T48 3975-3985 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T49 3994-3996 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T51 4179-4187 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T52 4188-4197 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T53 4358-4366 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T54 4367-4376 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T55 4576-4580 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T56 4820-4835 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T57 4826-4835 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T58 4842-4850 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T59 4853-4862 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T60 5301-5318 Disease denotes diabetes mellitus http://purl.obolibrary.org/obo/MONDO_0005015
T61 5322-5334 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T62 5430-5439 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T63 5460-5468 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T64 5796-5804 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T65 5807-5816 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T66 5868-5880 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T67 5882-5899 Disease denotes diabetes mellitus http://purl.obolibrary.org/obo/MONDO_0005015
T68 5914-5920 Disease denotes stroke http://purl.obolibrary.org/obo/MONDO_0005098|http://purl.obolibrary.org/obo/MONDO_0011057
T70 6178-6182 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T71 6302-6305 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T73 6347-6392 Disease denotes secondary haemophagocytic lymphohistiocytosis http://purl.obolibrary.org/obo/MONDO_0015542
T74 6394-6398 Disease denotes sHLH http://purl.obolibrary.org/obo/MONDO_0015542
T75 6412-6416 Disease denotes sHLH http://purl.obolibrary.org/obo/MONDO_0015542
T76 6528-6546 Disease denotes multiorgan failure http://purl.obolibrary.org/obo/MONDO_0043726
T77 6575-6591 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T78 6627-6631 Disease denotes sHLH http://purl.obolibrary.org/obo/MONDO_0015542
T79 6731-6735 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T80 6816-6820 Disease denotes sHLH http://purl.obolibrary.org/obo/MONDO_0015542
T81 6854-6862 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T82 6863-6873 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T83 6983-6988 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T84 7186-7194 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T85 7195-7204 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T86 7225-7240 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T87 7231-7240 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T88 7254-7256 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T90 7292-7294 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T92 7299-7309 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T93 7490-7499 Disease denotes arthritis http://purl.obolibrary.org/obo/MONDO_0005578
T94 7649-7658 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T95 7749-7765 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T96 7789-7791 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T98 7914-7916 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T100 7972-7981 Disease denotes arthritis http://purl.obolibrary.org/obo/MONDO_0005578
T101 7983-7993 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T102 8094-8096 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T104 8143-8152 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T105 8300-8302 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T107 8316-8318 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T109 8444-8454 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T110 8544-8557 Disease denotes polyarthritis http://purl.obolibrary.org/obo/MONDO_0024280
T111 8600-8622 Disease denotes hospitalized infection http://purl.obolibrary.org/obo/MONDO_0043544
T112 8613-8622 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T113 8755-8775 Disease denotes autoimmune disorders http://purl.obolibrary.org/obo/MONDO_0007179
T114 8903-8905 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T116 9049-9059 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T117 9166-9176 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T118 9291-9301 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T119 9584-9594 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T120 9648-9658 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T121 9740-9742 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T123 9749-9766 Disease denotes Diabetes mellitus http://purl.obolibrary.org/obo/MONDO_0005015
T124 9768-9791 Disease denotes cardiovascular diseases http://purl.obolibrary.org/obo/MONDO_0004995
T125 9793-9806 Disease denotes renal failure http://purl.obolibrary.org/obo/MONDO_0001106
T126 9808-9833 Disease denotes interstitial lung disease http://purl.obolibrary.org/obo/MONDO_0015925
T127 9821-9833 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T128 9839-9876 Disease denotes chronic obstructive pulmonary disease http://purl.obolibrary.org/obo/MONDO_0005002
T129 9859-9876 Disease denotes pulmonary disease http://purl.obolibrary.org/obo/MONDO_0005275
T130 9878-9882 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T131 9956-9969 Disease denotes infections in http://purl.obolibrary.org/obo/MONDO_0005550
T132 9970-9972 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T134 9991-9993 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T136 10021-10031 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T137 10179-10197 Disease denotes rheumatic diseases http://purl.obolibrary.org/obo/MONDO_0005554
T138 10201-10217 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T139 10346-10348 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T141 10529-10531 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T143 10595-10607 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T144 10615-10617 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T146 10741-10751 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T147 10829-10838 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T148 10917-10930 Disease denotes infections in http://purl.obolibrary.org/obo/MONDO_0005550
T149 10931-10933 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T151 11031-11044 Disease denotes infections in http://purl.obolibrary.org/obo/MONDO_0005550
T152 11045-11047 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T154 11140-11150 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T155 11189-11191 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T157 11256-11272 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T158 11364-11370 Disease denotes Zoster http://purl.obolibrary.org/obo/MONDO_0005609
T159 11371-11381 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T160 11658-11674 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T161 11759-11763 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T162 11906-11914 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T163 11973-11985 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T164 12140-12149 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T165 12254-12263 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T166 12385-12401 Disease denotes fungal infection http://purl.obolibrary.org/obo/MONDO_0002041
T167 12392-12401 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T168 12603-12607 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T169 12798-12806 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T170 12807-12816 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T171 12975-12983 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T172 12984-12993 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T173 13102-13118 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T174 13341-13349 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T175 13350-13359 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T176 13500-13508 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T177 13573-13582 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T178 13634-13644 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T179 13745-13747 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T181 13833-13835 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T183 13975-13984 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T184 14112-14121 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T185 14295-14317 Disease denotes hospitalized infection http://purl.obolibrary.org/obo/MONDO_0043544
T186 14308-14317 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T187 14544-14553 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T188 14686-14695 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T189 14735-14744 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T190 14757-14759 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T192 15284-15294 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T193 15331-15353 Disease denotes respiratory infections http://purl.obolibrary.org/obo/MONDO_0024355
T194 15412-15421 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T195 15427-15437 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T196 15515-15524 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T197 15860-15869 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T198 16029-16039 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T199 16087-16089 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T201 16258-16264 Disease denotes Zoster http://purl.obolibrary.org/obo/MONDO_0005609
T202 16277-16287 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T203 16501-16503 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T205 16944-16953 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T206 17049-17058 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T207 17382-17392 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T208 17766-17782 Disease denotes virus infections http://purl.obolibrary.org/obo/MONDO_0005108
T209 17832-17840 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T210 17959-17967 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T211 17970-17979 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T212 18020-18028 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T213 18225-18233 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T214 18334-18350 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T215 18402-18410 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T216 18477-18485 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T217 18647-18655 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T218 18897-18902 Disease denotes Ebola http://purl.obolibrary.org/obo/MONDO_0005737
T219 18903-18918 Disease denotes virus infection http://purl.obolibrary.org/obo/MONDO_0005108
T220 18909-18918 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T221 19094-19102 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T222 19105-19114 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T223 19267-19275 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T224 19447-19451 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T225 19786-19788 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T227 19834-19842 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T228 19920-19929 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T229 19992-20000 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T230 20001-20010 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T231 20313-20317 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T232 20408-20417 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T233 20630-20634 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T234 20667-20677 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T235 20762-20777 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T236 20768-20777 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T237 20928-20943 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T238 20934-20943 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T239 20999-21015 Disease denotes fungal infection http://purl.obolibrary.org/obo/MONDO_0002041
T240 21006-21015 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T241 21056-21060 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T242 21063-21098 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T243 21069-21098 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T244 21143-21149 Disease denotes Zoster http://purl.obolibrary.org/obo/MONDO_0005609
T245 21456-21458 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T247 21683-21687 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T248 22244-22248 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T249 22253-22262 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T250 22433-22441 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T251 22709-22718 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T252 23155-23163 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T253 23166-23175 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T254 23233-23237 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T255 23271-23279 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T256 23280-23289 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T257 23363-23366 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T259 23411-23417 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T260 23430-23448 Disease denotes multiorgan failure http://purl.obolibrary.org/obo/MONDO_0043726
T261 23673-23689 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T262 23738-23741 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T264 23812-23820 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T265 23974-23978 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T266 24005-24014 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T267 24251-24259 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T268 24496-24498 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T270 24599-24607 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T271 24608-24617 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T272 24779-24788 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T273 24799-24818 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T274 25094-25097 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T276 25105-25113 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T277 25114-25123 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T278 25229-25235 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T279 25438-25441 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T281 25487-25496 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T282 25528-25536 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T283 25799-25817 Disease denotes SARS-CoV infection http://purl.obolibrary.org/obo/MONDO_0005091
T284 25808-25817 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T285 25961-25967 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T286 26319-26323 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T287 26329-26338 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T288 26424-26432 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T289 26433-26442 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T290 26596-26604 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T291 27232-27241 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T292 27254-27260 Disease denotes Dengue http://purl.obolibrary.org/obo/MONDO_0005502
T293 27268-27273 Disease denotes Ebola http://purl.obolibrary.org/obo/MONDO_0005737
T294 27708-27710 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T296 27883-27886 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T298 27979-27988 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T299 27996-28004 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T300 28441-28443 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T302 28508-28517 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T303 28650-28658 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T304 28846-28855 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T305 29342-29351 Disease denotes Influenza http://purl.obolibrary.org/obo/MONDO_0005812
T306 29674-29678 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T307 29684-29693 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T308 29814-29822 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T309 29823-29832 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T310 29975-29990 Disease denotes viral pneumonia http://purl.obolibrary.org/obo/MONDO_0006012
T311 29981-29990 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T312 30012-30020 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T313 30133-30135 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T315 30171-30192 Disease denotes inflammatory disorder http://purl.obolibrary.org/obo/MONDO_0021166
T316 30194-30196 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T318 30214-30224 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T319 30393-30403 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T320 30429-30431 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T322 30468-30478 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T323 30498-30500 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T325 30571-30579 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T326 30934-30949 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T327 30940-30949 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T328 31004-31008 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T329 31027-31036 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T330 31144-31152 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T331 31153-31163 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T332 31221-31230 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T333 31248-31250 Disease denotes RA http://purl.obolibrary.org/obo/MONDO_0005272|http://purl.obolibrary.org/obo/MONDO_0008383
T335 31411-31420 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T336 31436-31439 Disease denotes CRS http://purl.obolibrary.org/obo/MONDO_0007399|http://purl.obolibrary.org/obo/MONDO_0017361
T338 31626-31630 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T339 31785-31800 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T340 31791-31800 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 156-159 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T2 175-176 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T3 540-541 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T4 695-708 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T5 1280-1281 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T6 1317-1318 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T7 1519-1520 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T8 1531-1536 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T9 1709-1715 http://purl.obolibrary.org/obo/CLO_0001302 denotes 3], [4
T10 2038-2041 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T11 2046-2047 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T12 2105-2117 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T13 2167-2168 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T14 2243-2244 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T15 3441-3454 http://purl.obolibrary.org/obo/PR_000001393 denotes interleukin 6
T16 3592-3596 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T17 3592-3596 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T18 3693-3695 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T19 4012-4013 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T20 4025-4030 http://purl.obolibrary.org/obo/CLO_0009985 denotes focus
T21 4228-4235 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T22 4241-4242 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T23 4518-4521 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T24 4550-4554 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T25 4628-4629 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T26 4637-4645 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T27 4667-4672 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T28 4680-4686 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T29 4680-4686 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T30 4680-4686 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T31 4688-4693 http://purl.obolibrary.org/obo/UBERON_0000948 denotes heart
T32 4688-4693 http://purl.obolibrary.org/obo/UBERON_0007100 denotes heart
T33 4688-4693 http://purl.obolibrary.org/obo/UBERON_0015228 denotes heart
T34 4688-4693 http://www.ebi.ac.uk/efo/EFO_0000815 denotes heart
T35 4695-4717 http://purl.obolibrary.org/obo/UBERON_0005409 denotes gastrointestinal tract
T36 4719-4732 http://purl.obolibrary.org/obo/UBERON_0001981 denotes blood vessels
T37 4719-4732 http://www.ebi.ac.uk/efo/EFO_0000817 denotes blood vessels
T38 4752-4756 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T39 4752-4756 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T40 4770-4780 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T41 4781-4786 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T42 4998-5001 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T43 5167-5171 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T44 5167-5171 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T45 5262-5265 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T46 5579-5580 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T47 6313-6314 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T48 6485-6486 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T49 6786-6787 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T50 6821-6824 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T51 6912-6913 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T52 6935-6948 http://purl.obolibrary.org/obo/PR_000001091 denotes interleukin-1
T53 6959-6963 http://purl.obolibrary.org/obo/PR_000001379 denotes IL-2
T54 6977-6981 http://purl.obolibrary.org/obo/CLO_0053704 denotes IL-8
T55 7533-7545 http://purl.obolibrary.org/obo/UBERON_0001155 denotes colonization
T56 7553-7559 http://purl.obolibrary.org/obo/UBERON_0000982 denotes joints
T57 7712-7713 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T58 7815-7816 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T59 7998-7999 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T60 8057-8059 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T61 8112-8113 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T62 8191-8192 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T63 8332-8333 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T64 8472-8473 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T65 8567-8570 http://purl.obolibrary.org/obo/CLO_0001562 denotes a 2
T66 8567-8570 http://purl.obolibrary.org/obo/CLO_0001563 denotes a 2
T67 8698-8699 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T68 8726-8739 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T69 8824-8832 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T70 8846-8849 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T71 8983-8991 http://purl.obolibrary.org/obo/CLO_0001658 denotes Activity
T72 9025-9026 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T73 9132-9133 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T74 9188-9195 http://purl.obolibrary.org/obo/CLO_0052947 denotes p = .01
T75 9216-9217 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T76 9488-9496 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T77 9542-9543 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T78 9744-9746 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T79 9821-9825 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T80 9821-9825 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T81 10272-10275 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T82 10453-10456 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T83 10543-10545 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T84 10957-10959 http://purl.obolibrary.org/obo/CLO_0053794 denotes 41
T85 11087-11088 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T86 11222-11223 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T87 11289-11290 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T88 11729-11733 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T89 11729-11733 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T90 11916-11918 http://purl.obolibrary.org/obo/CLO_0053799 denotes 45
T91 11968-11972 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T92 11968-11972 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T93 12068-12069 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T94 12151-12152 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T95 12204-12207 http://purl.obolibrary.org/obo/CLO_0050884 denotes ten
T96 12415-12419 http://purl.obolibrary.org/obo/CLO_0037048 denotes CI 1
T97 12569-12570 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T98 12636-12637 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T99 12732-12734 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T100 13153-13156 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T101 13465-13466 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T102 13523-13524 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T103 13687-13688 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T104 13726-13727 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T105 13798-13799 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T106 13950-13951 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T107 14238-14239 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T108 14268-14269 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T109 14433-14435 http://purl.obolibrary.org/obo/CLO_0001407 denotes 52
T110 14438-14439 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T111 15003-15004 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T112 15314-15321 http://purl.obolibrary.org/obo/CLO_0009985 denotes focused
T113 15450-15451 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T114 15580-15581 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T115 16265-16270 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T116 16539-16540 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T117 16557-16560 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T118 17007-17013 http://purl.obolibrary.org/obo/UBERON_0003100 denotes female
T119 17180-17181 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T120 17194-17196 http://purl.obolibrary.org/obo/CLO_0054055 denotes 71
T121 17414-17415 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T122 17581-17585 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T123 17625-17634 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T124 17643-17668 http://purl.obolibrary.org/obo/PR_000024990 denotes type I and II interferons
T125 17766-17771 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T126 17842-17843 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T127 18061-18062 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T128 18257-18264 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T129 18903-18908 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T130 18925-18928 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T131 18957-18958 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T132 18995-18996 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T133 19018-19025 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T134 19329-19334 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T135 19485-19490 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T136 19498-19503 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T137 19846-19847 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T138 20091-20096 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T139 20097-20101 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T140 20143-20151 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T141 20500-20504 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T142 20738-20742 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T143 21150-21155 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T144 21524-21527 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T145 21664-21671 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T146 21925-21930 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T147 21931-21935 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T148 21978-21986 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T149 22133-22138 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T150 22170-22171 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T151 22267-22268 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T152 22294-22297 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T153 22405-22411 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T154 22655-22659 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T155 22655-22659 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T156 22730-22731 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T157 22732-22737 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T158 23047-23048 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T159 23406-23410 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T160 23406-23410 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T161 23450-23452 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T162 23593-23600 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cells
T163 23625-23627 http://purl.obolibrary.org/obo/CLO_0001527 denotes 94
T164 23705-23715 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T165 23729-23736 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T166 23767-23768 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T167 23851-23852 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T168 24026-24027 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T169 24189-24190 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T170 24422-24423 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T171 24530-24533 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T172 24666-24667 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T173 24683-24686 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T174 25013-25014 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T175 25026-25027 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T176 25071-25072 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T177 25208-25209 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T178 25224-25228 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T179 25224-25228 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T180 25268-25271 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T181 25276-25279 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T182 25379-25384 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T183 25379-25384 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T184 25445-25446 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T185 25473-25475 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T186 25573-25584 http://purl.obolibrary.org/obo/CL_0000232 denotes erythrocyte
T187 25748-25750 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T188 25837-25838 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T189 25899-25907 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T190 25956-25960 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T191 25956-25960 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T192 26026-26027 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T193 26137-26142 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T194 26152-26156 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T195 26234-26237 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T196 26358-26363 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T197 26381-26382 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T198 26391-26392 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T199 26443-26446 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T200 26623-26628 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T201 26875-26878 http://purl.obolibrary.org/obo/CLO_0037126 denotes GAK
T202 26933-26938 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T203 26944-26948 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T204 26944-26948 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T205 26949-26954 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T206 26994-26999 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T207 27011-27014 http://purl.obolibrary.org/obo/CLO_0054060 denotes 102
T208 27245-27250 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T209 27261-27266 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T210 27274-27279 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T211 27307-27312 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T212 27621-27624 http://purl.obolibrary.org/obo/CLO_0037126 denotes GAK
T213 27632-27638 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T214 27749-27750 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T215 27907-27923 http://purl.obolibrary.org/obo/PR_000000017 denotes interferon gamma
T216 28127-28128 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T217 28430-28436 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T218 28867-28877 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T219 28912-28921 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T220 28997-29002 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T221 29042-29049 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T222 29066-29071 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T223 29090-29097 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T224 29192-29201 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T225 29352-29353 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T226 29354-29361 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T227 29379-29388 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T228 29467-29476 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T229 29478-29481 http://purl.obolibrary.org/obo/CLO_0053001 denotes 114
T230 29487-29488 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T231 29620-29621 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T232 30041-30042 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T233 30107-30108 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T234 30150-30151 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T235 30205-30206 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T236 30336-30337 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T237 30440-30448 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T238 31598-31601 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T239 31663-31673 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T240 31674-31679 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T241 31732-31740 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 584-586 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T2 789-804 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T3 827-832 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T4 946-966 Chemical denotes anti-rheumatic drugs http://purl.obolibrary.org/obo/CHEBI_35842
T5 961-966 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T6 1127-1132 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T7 1156-1158 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T8 1233-1235 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T9 1547-1557 Chemical denotes nucleotide http://purl.obolibrary.org/obo/CHEBI_36976
T10 2906-2930 Chemical denotes immunosuppressive agents http://purl.obolibrary.org/obo/CHEBI_35705
T11 2939-2954 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T12 3001-3006 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T13 3134-3139 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T14 3197-3199 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T15 3260-3271 Chemical denotes Chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T16 3276-3294 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T17 3341-3356 Chemical denotes antiviral drugs http://purl.obolibrary.org/obo/CHEBI_36044
T18 3341-3350 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T19 3351-3356 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T20 3456-3458 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T22 3994-3996 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T23 4094-4114 Chemical denotes anti-rheumatic drugs http://purl.obolibrary.org/obo/CHEBI_35842
T24 4109-4114 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T25 4479-4490 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T26 4601-4613 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T27 4646-4653 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T28 4953-4967 Chemical denotes angiotensin II http://purl.obolibrary.org/obo/CHEBI_2719|http://purl.obolibrary.org/obo/CHEBI_48432|http://purl.obolibrary.org/obo/CHEBI_58506
T31 4953-4964 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T32 4965-4967 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T33 5049-5063 Chemical denotes angiotensin II http://purl.obolibrary.org/obo/CHEBI_2719|http://purl.obolibrary.org/obo/CHEBI_48432|http://purl.obolibrary.org/obo/CHEBI_58506
T36 5049-5060 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T37 5061-5063 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T38 5345-5355 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T39 5359-5370 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T40 6951-6953 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T42 6959-6961 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T44 6965-6967 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T46 6971-6973 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T48 6977-6979 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T50 7034-7053 Chemical denotes chemokine ligand 10 http://purl.obolibrary.org/obo/CHEBI_138157
T51 7044-7050 Chemical denotes ligand http://purl.obolibrary.org/obo/CHEBI_52214
T52 7055-7061 Chemical denotes CXCL10 http://purl.obolibrary.org/obo/CHEBI_138157
T53 7067-7069 Chemical denotes CC http://purl.obolibrary.org/obo/CHEBI_28940
T54 7080-7086 Chemical denotes ligand http://purl.obolibrary.org/obo/CHEBI_52214
T55 7254-7256 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T56 7292-7294 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T57 7789-7791 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T58 7914-7916 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T59 8094-8096 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T60 8300-8302 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T61 8316-8318 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T62 8372-8374 Chemical denotes RR http://purl.obolibrary.org/obo/CHEBI_73811
T63 8417-8419 Chemical denotes RR http://purl.obolibrary.org/obo/CHEBI_73811
T64 8903-8905 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T65 9740-9742 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T66 9970-9972 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T67 9991-9993 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T68 10169-10174 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T69 10262-10268 Chemical denotes NSAIDs http://purl.obolibrary.org/obo/CHEBI_35475
T70 10309-10324 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T71 10326-10328 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T73 10346-10348 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T74 10529-10531 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T75 10560-10562 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T77 10615-10617 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T78 10889-10891 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T80 10931-10933 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T81 11045-11047 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T82 11070-11072 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T84 11189-11191 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T85 11211-11213 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T87 11445-11447 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T89 11479-11481 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T91 11828-11830 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T93 12103-12105 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T95 12306-12308 Chemical denotes RR http://purl.obolibrary.org/obo/CHEBI_73811
T96 12403-12405 Chemical denotes RR http://purl.obolibrary.org/obo/CHEBI_73811
T97 12550-12552 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T99 12718-12720 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T101 12835-12837 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T103 13021-13023 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T105 13078-13084 Chemical denotes NSAIDs http://purl.obolibrary.org/obo/CHEBI_35475
T106 13143-13152 Chemical denotes Ibuprofen http://purl.obolibrary.org/obo/CHEBI_5855
T107 13415-13421 Chemical denotes NSAIDs http://purl.obolibrary.org/obo/CHEBI_35475
T108 13745-13747 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T109 13833-13835 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T110 13914-13929 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T111 14012-14014 Chemical denotes RR http://purl.obolibrary.org/obo/CHEBI_73811
T112 14137-14139 Chemical denotes RR http://purl.obolibrary.org/obo/CHEBI_73811
T113 14322-14334 Chemical denotes methotrexate http://purl.obolibrary.org/obo/CHEBI_44185|http://purl.obolibrary.org/obo/CHEBI_50681
T115 14345-14347 Chemical denotes RR http://purl.obolibrary.org/obo/CHEBI_73811
T116 14376-14394 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T117 14405-14407 Chemical denotes RR http://purl.obolibrary.org/obo/CHEBI_73811
T118 14576-14579 Chemical denotes MTX http://purl.obolibrary.org/obo/CHEBI_44185
T119 14581-14583 Chemical denotes RR http://purl.obolibrary.org/obo/CHEBI_73811
T120 14757-14759 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T121 16073-16083 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T122 16087-16089 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T123 16173-16184 Chemical denotes tofacitinib http://purl.obolibrary.org/obo/CHEBI_71200
T124 16304-16315 Chemical denotes tofacitinib http://purl.obolibrary.org/obo/CHEBI_71200
T125 16501-16503 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T126 16814-16825 Chemical denotes tofacitinib http://purl.obolibrary.org/obo/CHEBI_71200
T127 17019-17029 Chemical denotes prednisone http://purl.obolibrary.org/obo/CHEBI_8382
T128 17266-17276 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T129 17615-17624 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T130 17654-17656 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T131 17798-17808 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T132 17853-17873 Chemical denotes anti-rheumatic drugs http://purl.obolibrary.org/obo/CHEBI_35842
T133 17868-17873 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T134 18294-18309 Chemical denotes antiviral drugs http://purl.obolibrary.org/obo/CHEBI_36044
T135 18294-18303 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T136 18304-18309 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T137 18509-18514 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T138 18569-18579 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T139 18581-18590 Chemical denotes ribavirin http://purl.obolibrary.org/obo/CHEBI_63580
T140 18596-18615 Chemical denotes lopinavir-ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T141 18596-18605 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T142 18606-18615 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T143 18711-18730 Chemical denotes lopinavir-ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T144 18711-18720 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T145 18721-18730 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T146 18813-18823 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T147 18828-18837 Chemical denotes adenosine http://purl.obolibrary.org/obo/CHEBI_16335
T148 18969-18978 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T149 19135-19154 Chemical denotes lopinavir-ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T150 19135-19144 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T151 19145-19154 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T152 19204-19209 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T153 19746-19751 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T154 19786-19788 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T155 19968-19988 Chemical denotes anti-rheumatic drugs http://purl.obolibrary.org/obo/CHEBI_35842
T156 19983-19988 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T157 20022-20033 Chemical denotes Chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T158 20247-20249 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T160 20252-20262 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T161 20682-20692 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T162 20783-20789 Chemical denotes NSAIDs http://purl.obolibrary.org/obo/CHEBI_35475
T163 21023-21034 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T164 21163-21173 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T165 21175-21181 Chemical denotes NSAIDs http://purl.obolibrary.org/obo/CHEBI_35475
T166 21184-21220 Chemical denotes nonsteroidal anti-inflammatory drugs http://purl.obolibrary.org/obo/CHEBI_35475
T167 21197-21220 Chemical denotes anti-inflammatory drugs http://purl.obolibrary.org/obo/CHEBI_35472
T168 21215-21220 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T169 21228-21239 Chemical denotes Chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T170 21240-21258 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T171 21259-21270 Chemical denotes Chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T172 21275-21293 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T173 21324-21329 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T174 21456-21458 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T175 21480-21491 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T176 21598-21602 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T177 21863-21874 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T178 22196-22200 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T179 22282-22293 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T180 22498-22503 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T181 22593-22604 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T182 22846-22864 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T183 22918-22929 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T184 23188-23190 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T186 23197-23199 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T188 23832-23834 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T190 23841-23843 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T192 24043-24045 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T194 24278-24289 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T195 24325-24331 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T196 24443-24454 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360
T197 24456-24458 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T199 24496-24498 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T200 24631-24633 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T202 24674-24676 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T203 24942-24944 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T205 24947-24956 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T206 25360-25362 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T208 25763-25773 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T209 25921-25932 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T210 26000-26007 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T211 26274-26284 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T212 26550-26560 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T213 26819-26826 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T214 27137-27146 Chemical denotes erlotinib http://purl.obolibrary.org/obo/CHEBI_114785
T215 27148-27157 Chemical denotes sunitinib http://purl.obolibrary.org/obo/CHEBI_38940
T216 27159-27170 Chemical denotes ruxolitinib http://purl.obolibrary.org/obo/CHEBI_66919
T217 27559-27568 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T218 27708-27710 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T219 27761-27770 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T220 27898-27900 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T222 27907-27917 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T223 27918-27923 Chemical denotes gamma http://purl.obolibrary.org/obo/CHEBI_30212
T224 28082-28085 Chemical denotes CYP http://purl.obolibrary.org/obo/CHEBI_38559
T225 28086-28090 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T226 28122-28126 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T227 28192-28207 Chemical denotes antiviral drugs http://purl.obolibrary.org/obo/CHEBI_36044
T228 28192-28201 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T229 28202-28207 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T230 28216-28235 Chemical denotes lopinavir/ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T231 28216-28225 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T232 28226-28235 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T233 28240-28250 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T234 28273-28284 Chemical denotes tofacitinib http://purl.obolibrary.org/obo/CHEBI_71200
T235 28407-28417 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T236 28441-28443 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T237 28685-28696 Chemical denotes ruxolitinib http://purl.obolibrary.org/obo/CHEBI_66919
T238 28975-28985 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T239 30133-30135 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T240 30194-30196 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T241 30311-30316 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T242 30429-30431 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T243 30498-30500 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T244 30871-30873 Chemical denotes CS http://purl.obolibrary.org/obo/CHEBI_73462|http://purl.obolibrary.org/obo/CHEBI_50858
T246 31038-31049 Chemical denotes Chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T247 31054-31072 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T248 31248-31250 Chemical denotes RA http://purl.obolibrary.org/obo/CHEBI_73810
T249 31287-31289 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T251 31292-31302 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T252 31306-31317 Chemical denotes tocilizumab http://purl.obolibrary.org/obo/CHEBI_64360

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 3063-3075 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T2 4295-4310 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T3 4413-4425 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T4 4820-4835 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T5 6046-6057 http://purl.obolibrary.org/obo/GO_0006412 denotes translation
T6 6083-6096 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T7 6575-6591 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T8 6989-6997 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T9 6989-6997 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T10 6989-6997 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T11 6989-6997 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T12 7225-7240 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T13 7749-7765 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T14 10201-10217 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T15 10595-10607 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T16 11256-11272 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T17 11498-11525 http://purl.obolibrary.org/obo/GO_0050777 denotes inhibit the immune response
T18 11510-11525 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T19 11614-11635 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T20 11658-11674 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T21 11973-11985 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T22 13102-13118 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T23 17581-17603 http://purl.obolibrary.org/obo/GO_0002456 denotes cell-mediated immunity
T24 17581-17603 http://purl.obolibrary.org/obo/GO_0002449 denotes cell-mediated immunity
T25 17625-17634 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T26 18334-18350 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T27 20097-20108 http://purl.obolibrary.org/obo/GO_0140253 denotes cell fusion
T28 20097-20108 http://purl.obolibrary.org/obo/GO_0045026 denotes cell fusion
T29 20097-20108 http://purl.obolibrary.org/obo/GO_0000768 denotes cell fusion
T30 20097-20108 http://purl.obolibrary.org/obo/GO_0000747 denotes cell fusion
T31 20134-20151 http://purl.obolibrary.org/obo/GO_0038024 denotes receptor activity
T32 20171-20193 http://purl.obolibrary.org/obo/GO_0033578 denotes terminal glycosylation
T33 20180-20193 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T34 20473-20490 http://purl.obolibrary.org/obo/GO_0046718 denotes viral penetration
T35 20530-20541 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis
T36 20711-20728 http://purl.obolibrary.org/obo/GO_0046718 denotes viral penetration
T37 20762-20777 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T38 20808-20825 http://purl.obolibrary.org/obo/GO_0046718 denotes viral penetration
T39 20928-20943 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T40 21633-21639 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T41 21931-21942 http://purl.obolibrary.org/obo/GO_0140253 denotes cell fusion
T42 21931-21942 http://purl.obolibrary.org/obo/GO_0045026 denotes cell fusion
T43 21931-21942 http://purl.obolibrary.org/obo/GO_0000768 denotes cell fusion
T44 21931-21942 http://purl.obolibrary.org/obo/GO_0000747 denotes cell fusion
T45 21969-21986 http://purl.obolibrary.org/obo/GO_0038024 denotes receptor activity
T46 22010-22032 http://purl.obolibrary.org/obo/GO_0033578 denotes terminal glycosylation
T47 22019-22032 http://purl.obolibrary.org/obo/GO_0070085 denotes glycosylation
T48 23384-23401 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T49 23384-23401 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T50 23649-23664 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T51 23673-23689 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T52 26543-26560 http://purl.obolibrary.org/obo/GO_0033673 denotes kinase inhibitors
T53 26637-26666 http://purl.obolibrary.org/obo/GO_0006898 denotes receptor-mediated endocytosis
T54 26655-26666 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis
T55 26696-26739 http://purl.obolibrary.org/obo/GO_2000369 denotes regulators of clathrin-mediated endocytosis
T56 26710-26739 http://purl.obolibrary.org/obo/GO_0072583 denotes clathrin-mediated endocytosis
T57 26728-26739 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis
T58 26847-26853 http://purl.obolibrary.org/obo/GO_0016538 denotes cyclin
T59 27854-27875 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T60 28590-28619 http://purl.obolibrary.org/obo/GO_0072583 denotes clathrin-mediated endocytosis
T61 28608-28619 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis
T62 28766-28789 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune responses
T63 28801-28818 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T64 28801-28818 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T65 28881-28894 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T66 28907-28929 http://purl.obolibrary.org/obo/GO_0097696 denotes STAT signaling pathway
T67 28912-28929 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T68 28912-28921 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T69 29192-29209 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T70 29192-29201 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T71 29310-29319 http://purl.obolibrary.org/obo/GO_0016032 denotes virulence
T72 29310-29319 http://purl.obolibrary.org/obo/GO_0009405 denotes virulence
T73 29379-29388 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T74 29467-29476 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T75 30934-30949 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T76 31785-31800 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-44 Sentence denotes COVID-19 infection and rheumatoid arthritis:
T2 45-63 Sentence denotes Faraway, so close!
T3 65-73 Sentence denotes Abstract
T4 74-201 Sentence denotes The outbreak of the new coronavirus infections COVID-19 in December 2019 in China has quickly become a global health emergency.
T5 202-469 Sentence denotes Given the lack of specific anti-viral therapies, the current management of severe acute respiratory syndrome coronaviruses (SARS-CoV-2) is mainly supportive, even though several compounds are now under investigation for the treatment of this life-threatening disease.
T6 470-833 Sentence denotes COVID-19 pandemic is certainly conditioning the treatment strategy of a complex disorder as rheumatoid arthritis (RA), whose infectious risk is increased compared to the general population because of an overall impairment of immune system typical of autoimmune diseases combined with the iatrogenic effect generated by corticosteroids and immunosuppressive drugs.
T7 834-1029 Sentence denotes However, the increasing knowledge about the pathophysiology of SARS-CoV-2 infection is leading to consider some anti-rheumatic drugs as potential treatment options for the management of COVID-19.
T8 1030-1245 Sentence denotes In this review we will critically analyse the evidences on either positive or negative effect of drugs commonly used to treat RA in this particular scenario, in order to optimize the current approach to RA patients.
T9 1247-1262 Sentence denotes 1 Introduction
T10 1263-1470 Sentence denotes In December 2019 a new type of pneumonia supported by a novel member of the coronoviridae family named SARS-CoV-2 (severe acute respiratory coronavirus 2 syndrome) developed from Wuhan Province in China [1].
T11 1471-1587 Sentence denotes Phylogenetic analysis demonstrated that this is a different virus with ~80% nucleotide identity with SARS-CoV-1 [2].
T12 1588-1728 Sentence denotes The disease caused by SARS-CoV-2 is characterized by dry cough, fever, dyspnea and fatigue, accompanied by lymphopenia [[3], [4], [5], [6]].
T13 1729-1996 Sentence denotes In more severe cases (apparently up to 15–20% of infected patients) the picture may become more complicated by the onset of interstitial pneumonia with alveolar damage, which clinically can lead to severe Acute Respiratory Distress Syndrome (ARDS) and even death [7].
T14 1997-2273 Sentence denotes Since the initial outbreak, the epidemic has had a rapid global spread worldwide which led the World Health Organization (WHO) to declare the disease now called COVID-19 a Public Health Emergency of International Concern on 30th January 2020 and a pandemic on 11th March 2020.
T15 2274-2448 Sentence denotes The epidemiological picture is constantly evolving, and data updated as of March 17th count 159 countries involved with more than 185,000 cases and 7500 confirmed deaths [8].
T16 2449-2647 Sentence denotes In this context of growing health emergency, clarifying the relationship between COVID-19 and the population of fragile patients suffering from immune-rheumatological diseases is absolutely crucial.
T17 2648-3011 Sentence denotes On the one hand, the rapid and uncontrolled spread of the epidemic can clearly generate even more concerns in rheumatic patients, which are intrinsically characterized by an increased infectious risk due to the disease itself and to the iatrogenic effect of immunosuppressive agents such as corticosteroids and synthetic or biological disease-modifying drugs [9].
T18 3012-3259 Sentence denotes On the other hand, the growing knowledge about the pathogenesis of SARS-CoV-2 infection is leading to the introduction of drugs commonly used for the treatment of rheumatoid arthritis (RA) even for the management of more complex cases of COVID-19.
T19 3260-3416 Sentence denotes Chloroquine and hydroxychloroquine have now been permanently included, alongside antiviral drugs, in protocols for the treatment of COVID-19 pneumonia [10].
T20 3417-3697 Sentence denotes In addition, the use of interleukin 6 (IL-6) blockers seems to be very promising for the management of the massive cytokine storm associated to the development of the typical lung damage and the consequent ARDS occurring in the most aggressive patterns of SARS-CoV infection [11].
T21 3698-3912 Sentence denotes Therefore, waiting for observational data on the incidence of COVID-19 in rheumatological patients, the best strategy to manage immune-rheumatological diseases during this emergency period is still far to be clear.
T22 3913-4151 Sentence denotes The purpose of this review is to provide an overview on viral infectious risk in RA patients, with a particular focus on the knowledge about the current new pandemic and the use of anti-rheumatic drugs in this context of health emergency.
T23 4153-4197 Sentence denotes 2 The pathophysiology of COVID-19 infection
T24 4198-4285 Sentence denotes Coronaviruses are the largest viruses with a positive-sense single-stranded-RNA genome.
T25 4286-4474 Sentence denotes The host immune response is by one side essential for the resolution of COVID-19 infection, but it can also be crucial for the pathogenesis of major clinical manifestations of the disease.
T26 4475-4619 Sentence denotes The angiotensin-converting enzyme 2 (ACE2) has been identified as the host cell-surface receptor for SARS-CoV2 envelope spike glycoprotein [12].
T27 4620-4841 Sentence denotes ACE2 is a type I membrane protein expressed on cells in the kidney, heart, gastrointestinal tract, blood vessels, and, importantly, lung AT2 alveolar epithelial cells, which are particularly prone to viral infection [13].
T28 4842-4994 Sentence denotes SARS-CoV-2 infection leads to the downregulation of ACE2 expression, thus resulting in excessive production of angiotensin II by the related enzyme ACE.
T29 4995-5225 Sentence denotes It has been suggested that the stimulation of type 1a angiotensin II receptor (AGTR1A) increases pulmonary vascular permeability, thus potentially explaining the increased lung damage when the expression of ACE2 is decreased [14].
T30 5226-5474 Sentence denotes Due to this mechanism of action, it has been postulated that subjects with diabetes mellitus or hypertension using ACE-inhibitors or angiotensin receptor blockers may have an increase of both the risk of infection and the severity of COVID-19 [15].
T31 5475-5687 Sentence denotes As only scarce evidence supports this hypothesis, the European Society of Cardiology recently published a position statement that strongly recommends continuing these treatments despite the current epidemic [16].
T32 5688-5959 Sentence denotes An additional point to be clarified is also the role of the genetic predisposition for an increased risk of SARS-CoV-2 infection due to ACE2 polymorphisms that have been linked to hypertension, diabetes mellitus, and cerebral stroke, especially in Asian populations [15].
T33 5960-6162 Sentence denotes The viral RNA genome is released into the cytoplasm, and the RNA is uncoated to allow translation of the two polyproteins, transcription of the sub-genomic RNAs and replication of the viral genome [17].
T34 6163-6400 Sentence denotes Progression to ARDS is associated with the upregulation of pro-inflammatory cytokines and chemokines, known as Cytokines Release Syndrome (CRS), with a pattern very similar to that of secondary haemophagocytic lymphohistiocytosis (sHLH).
T35 6401-6600 Sentence denotes In adults, sHLH is an under-recognized, hyperinflammatory syndrome characterized by a massive and fatal hypercytokinaemia with multiorgan failure, most commonly triggered by viral infections [18,19].
T36 6601-6785 Sentence denotes Main clinical features of sHLH include unremitting fever, hyperferritinaemia and cytopenias, and pulmonary involvement (including ARDS) occurring in approximately 50% of patients [20].
T37 6786-7105 Sentence denotes A cytokine profile resembling sHLH has been reported in most severe COVID-19 infections, characterized by increased levels of a number of cytokines (interleukin-1β [IL-1β], IL-2, IL-6, IL-7, IL-8, tumor necrosis factor-α [TNF]) and chemokines (CXC-chemokine ligand 10 [CXCL10] and CC-chemokine ligand 2 [CCL2]) [21,22].
T38 7106-7205 Sentence denotes The management of this cytokine storm is one of the major unmet needs regarding COVID-19 infection.
T39 7207-7266 Sentence denotes 3 Is the risk of viral infection increased in RA patients?
T40 7267-7386 Sentence denotes The relationship between RA and infectious diseases is very complex and can be interpreted in two different directions.
T41 7387-7681 Sentence denotes On the one hand, in fact, the potential role of external microorganisms in producing acute and chronic arthritis in the form of either the direct colonization of the joints by the pathogen or the aberrant autoimmune reaction produced by the host response to the infection is well known [23,24].
T42 7682-7922 Sentence denotes Few studies have investigated a potential link between respiratory viral infections and the development of RA [25] and in particular a Korean study reported parainfluenza and coronavirus to be associated with the number of incident RA [26].
T43 7923-8074 Sentence denotes In addition, in patients with overt inflammatory arthritis, infections are a major concern as they can contribute to disease flares [[27], [28], [29]].
T44 8075-8190 Sentence denotes On the other hand, RA patients carry a documented increased risk of infection compared with the general population.
T45 8191-8460 Sentence denotes A population-based study by Doran and colleagues compared two matched groups of 609 patients with or without RA showing that RA patients had a significantly higher risk of serious (RR 1.53, 95% CI 1.41–1.65) and hospitalized (RR 1.88, 95% CI 1.71–2.07) infections [30].
T46 8461-8659 Sentence denotes Similarly, a prospective cohort study conducted on 2108 patients with inflammatory polyarthritis reported a 2- to 4-fold increased risk of hospitalized infection compared to healthy population [31].
T47 8660-8833 Sentence denotes This trend is primarily the result of a general impairment of the immune system typical of all autoimmune disorders and strictly dependent on the degree of disease activity.
T48 8834-9202 Sentence denotes In fact, it has been demonstrated by an analysis conducted in 16,242 RA patients from the US CORRONA registry that each 0.6 unit increase in Disease Activity Score 28 (DAS28) corresponded to a 25% increased rate of infections requiring hospitalization (Incident rate ratio [IRR] 1.25, p = .03) and a 4% increased rate of outpatient infections (IRR 1.04, p = .01) [32].
T49 9203-9614 Sentence denotes In addition, a subsequent report from the same registry showed that the risk of serious infections increased progressively from patients achieving clinical remission to those achieving low (adjusted IRR 1.69, 95% CI 1.32–2.15) or moderate (adjusted IRR 1.30, 95% CI 1.09–1.56) disease activity, demonstrating the importance of maintaining a good disease control in order to reduce infectious complications [33].
T50 9615-9748 Sentence denotes Another important determinant of infectious risk is the presence of comorbidities, which very often complicate the course of RA [34].
T51 9749-9981 Sentence denotes Diabetes mellitus, cardiovascular diseases, renal failure, interstitial lung disease, and chronic obstructive pulmonary disease (COPD) are all concomitant disorders associated with an increased incidence of infections in RA [27,35].
T52 9982-10150 Sentence denotes Finally, RA can also be complicated by infections caused by the iatrogenic effect of immunosuppressive therapies, which will be discussed in detail in the next section.
T53 10152-10235 Sentence denotes 4 The impact of drugs for rheumatic diseases on viral infections: what do we know?
T54 10237-10268 Sentence denotes 4.1 Corticosteroids and NSAIDs
T55 10269-10547 Sentence denotes It has now been more than 70 years that corticosteroids (CS) are pivotal for RA management and their role as remission inducer and bridging therapy for the management of disease flare has recently been renewed by the latest update of EULAR recommendations for RA treatment [36].
T56 10548-10847 Sentence denotes Even though CS efficacy in rapidly suppressing inflammation during RA initial course or flares is well recognized [37], their downside is the broad spectrum of adverse events, including severe infections and the high risk of developing comorbidities further increasing the risk of infection [27,38].
T57 10848-11117 Sentence denotes Although RCTs conducted in the past with CS showed no higher risk of infections in RA patients [[39], [40], [41]], cohort and case-control studies reported increased rates of overall infections in RA patients treated with CS, according to a dose-dependent fashion [42].
T58 11118-11273 Sentence denotes The majority of these infectious events are of bacterial etiology, but RA patients receiving CS exhibit a greater risk of developing even viral infections.
T59 11274-11472 Sentence denotes As an example, a 2012 retrospective cohort-study demonstrated an increased risk of Herpes Zoster infections with an incidence rate of 8.54 cases per 1000 patient-years in CS treated population [29].
T60 11473-11769 Sentence denotes Thus, CS on the one hand inhibit the immune response and delay the clearance of the pathogen, while on the other hand they suppress the host inflammatory response, which in the case of viral infections of the respiratory tract is the major responsible for lung damage and occurrence of ARDS [43].
T61 11770-12019 Sentence denotes The latter represented the rational for the widely use of CS for the management of Middle East respiratory syndrome (MERS)-CoV [44] and SARS-CoV [45] outbreaks, both histologically characterized by lung inflammation and diffuse alveolar damage [46].
T62 12020-12150 Sentence denotes However, evidence from the literature points to a predominantly negative effect of CS in the management of this type of infection.
T63 12151-12343 Sentence denotes A 2019 systematic review and meta-analysis including ten observational studies (n = 6548) conducted in influenza reported increased mortality (risk ratio [RR] 1.75, 95% CI 1.3–2.4; p = .0002),
T64 12344-12558 Sentence denotes increased rate of secondary bacterial or fungal infection (RR 2·0, 95% CI 1·0–3·8; p = .04), and longer stay in an intensive care unit (mean difference 2.1, 95% CI 1.2–3.1; p < .0001) in patients receiving CS [47].
T65 12559-12736 Sentence denotes Moreover, a review exploring treatments for ARDS, including six studies with a total of 574 patients, concluded that insufficient evidence exists to recommend CS treatment [48].
T66 12737-12905 Sentence denotes Overall, no clear reason exists to expect that patients with COVID-19 infection will benefit from CS, and they might be more likely to be harmed with such therapy [49].
T67 12906-13065 Sentence denotes In fact, current interim guidance from WHO on clinical management of COVID-19 infection advises against the use of CS unless indicated for another reason [10].
T68 13066-13142 Sentence denotes The role of NSAIDs in the course of viral infections is still controversial.
T69 13143-13385 Sentence denotes Ibuprofen has been demonstrated to induce an overexpression of ACE2 when used in diabetic rats [50] and this effect might theoretically increase the susceptibility and worsen the clinical course of COVID-19 infection in treated patients [15].
T70 13386-13583 Sentence denotes In addition, the use of both NSAIDs and acetaminophen could be associated with a masking of the fever rise during COVID-19, resulting in a delay in diagnosis and proper management of the infection.
T71 13585-13598 Sentence denotes 4.2 csDMARDs
T72 13599-13889 Sentence denotes The most comprehensive analysis of infectious risk in patients treated with csDMARDs is a retrospective, longitudinal study of a population-based RA cohort using an administrative database including a total of 27,710 individuals with RA and providing 162,710 person-years of follow-up [51].
T73 13890-14163 Sentence denotes Use of csDMARDs without corticosteroids was associated with a small decrease in mild infection risk (adjusted rate ratio [RR] 0.90, 95% confidence interval [95% CI] 0.88–0.93) and was not associated with increased serious infection risk (adjusted RR 0.92, 95% CI 0.85–1.0).
T74 14164-14437 Sentence denotes Similarly, another retrospective analysis conducted on 1993 patients from a claim database demonstrated a slightly reduced risk of hospitalized infection for methotrexate (adjusted RR 0.81, 95% CI 0.70–0.93) and hydroxychloroquine (adjusted RR 0.74, 95% CI 0.62–0.89) [52].
T75 14438-14584 Sentence denotes A recent systematic review and meta-analysis of the literature confirmed the lack of an increased risk of infection in patients receiving MTX (RR:
T76 14585-14615 Sentence denotes 1.14; 95% CI, 0.98–1.34) [53].
T77 14616-14708 Sentence denotes However, all these reports provided no data on the risk of stratified infection by pathogen.
T78 14710-14722 Sentence denotes 4.3 bDMARDs
T79 14723-14886 Sentence denotes The risk of infection observed in RA patients treated with bDMARDs is generally considered slightly higher (from 1.5- up to 2-fold) compared with csDMARDs [27,54].
T80 14887-15156 Sentence denotes This evidence recurred in most RCTs [55] and observational registry studies [[56], [57], [58]] and was confirmed by a recent meta-analysis which showed that this risk is progressively increasing in relation to the use of bDMARDs at higher than recommended dosages [59].
T81 15157-15308 Sentence denotes Following the results of comparative metanalyses and real-life studies, abatacept is accepted as the safest bDMARD in terms of infectious risk [60,61].
T82 15309-15394 Sentence denotes Data focused on viral respiratory infections in bDMARD cohort are still very limited.
T83 15395-15719 Sentence denotes The incidence of influenza-like infections observed in a cohort of 159 Italian patients treated with bDMARDs during the influenza season 2009–2010 was higher than the value reported in a wide sample of Italian population in the same period, even though no important complications or hospitalizations have been reported [62].
T84 15720-15967 Sentence denotes Overall, post-marketing experience is relatively reassuring that anti-TNF treated patients may not be at any specifically increased risk of influenza and that severe adverse outcomes, including death, do not appear to be exceedingly frequent [63].
T85 15969-15982 Sentence denotes 4.4 tsDMARDs
T86 15983-16293 Sentence denotes The overall risk of serious and opportunistic infections observed with Janus Kinase (JAK) inhibitors in RA patients is roughly comparable with bDMARDs [64,65], although these early years of tofacitinib and baricitinib use have raised the issue of an increased risk of Herpes Zoster virus (HZV) infections [66].
T87 16294-16538 Sentence denotes Data from tofacitinib pooled population enrolled in RCTs showed an HZV incidence rate of 4.0 per 100 patient-years (with greater incidence in geographic area with high HZV endemicity), doubling the rates of RA patients not receiving JAKis [67].
T88 16539-16690 Sentence denotes A similar picture has also been observed in the overall development program of baricitinib, with an incidence rate of 3.2 cases per patient-years [68].
T89 16691-16995 Sentence denotes The subsequent real-life experience from US claim databases revealed that the risk of HZV was higher in patients receiving tofacitinib compared to those treated with abatacept (aHR 2.01 (95% CI 1.40; 2.88) [69], and the risk of serious hospitalized HZV infection is 2-fold higher versus all bDMARDs [70].
T90 16996-17198 Sentence denotes Older age, female sex, prednisone >7.5 mg/day, prior infection, and greater number of hospitalizations were associated with increased HZV risk, whereas vaccination was associated with a lower risk [71].
T91 17199-17446 Sentence denotes More recent reports from RCTs conducted with novel JAK-1 selective inhibitors upadacitinib and filgotinib have basically confirmed the same trend, suggesting that the increase in HZV infections can be considered as a class effect of JAKis [72,73].
T92 17447-17705 Sentence denotes Although the exact mechanism by which HZV reactivation occurs in the context of JAK inhibition is unclear, the downregulation of both cell-mediated immunity and innate antiviral signaling through type I and II interferons (IFN) is likely to be involved [74].
T93 17706-17809 Sentence denotes Currently, no data are available on the risk of respiratory virus infections carried by JAK inhibitors.
T94 17811-17874 Sentence denotes 5 The management of COVID-19: a room for anti-rheumatic drugs?
T95 17875-18162 Sentence denotes Currently, vaccines and approved targeted therapeutics for the treatment of the new SARS-CoV-2 infection are still lacking and the management of COVID-19 is only supportive, even though a multitude of compounds are now under investigation for the treatment of this emerging disease [75].
T96 18163-18351 Sentence denotes The need to urgently identify an effective approach to manage COVID-19 led to the strategy of testing the efficacy of the existing antiviral drugs commonly used for other viral infections.
T97 18352-18661 Sentence denotes In particular, considering the similarity between SARS-CoV-2 and other Betacoronavirus associated with previous epidemics as SARS-CoV and MERS-Cov, the same drugs used with controversial results for these conditions (interferon, ribavirin, and lopinavir-ritonavir) have been considered even for COVID-19 [76].
T98 18662-18799 Sentence denotes Anecdotal cases have demonstrated the ability of lopinavir-ritonavir to significantly reduce viral load and improve disease outcome [77].
T99 18800-19120 Sentence denotes In addition, remdesivir, an adenosine analogue currently under development for the management of Ebola virus infection [78], has been recently recognized as a promising antiviral therapy against a wide spectrum of RNA viruses [79] and showed good preliminary in vitro results in the control of SARS-CoV-2 infection [80].
T100 19121-19281 Sentence denotes Consequently, lopinavir-ritonavir and remdesevir are currently the only anti-viral drugs included in the more severe case management protocols of COVID-19 [10].
T101 19282-19512 Sentence denotes Recent reports described the potential role of human monoclonal antibodies that bind the coronavirus spike receptor binding domain, leading to the neutralization of SARS-CoV2 capability to interact with human target cells [81,82].
T102 19513-19692 Sentence denotes However, at the moment these can only be considered as potential treatment options for the future, but they are obviously not available for the management of the current pandemic.
T103 19693-19941 Sentence denotes Beyond the use of specific anti-viral products, many drugs commonly used in the treatment of RA have been proposed as possible therapies for COVID-19 as a consequence of the increased knowledge about the pathophysiology of the infection (Table 1 ).
T104 19942-20011 Sentence denotes Table 1 Potential role of anti-rheumatic drugs in COVID-19 infection.
T105 20012-20021 Sentence denotes PROS CONS
T106 20022-20227 Sentence denotes Chloroquine Anti-viral effect (increase of endosomal pH required for virus/cell fusion, inhibition of toll-like receptor activity, interference with terminal glycosylation of the cellular receptor ACE 2) –
T107 20228-20246 Sentence denotes Hydroxychloroquine
T108 20247-20378 Sentence denotes IL-6 inhibitors Treatment of cytokine storm manifestations during ARDS Lack of definite criteria to identify patients to be treated
T109 20379-20442 Sentence denotes Potential community-acquired pneumonia due to immunosuppression
T110 20443-20579 Sentence denotes Baricitinib Interference with viral penetration into the cell by blocking NAK-mediated endocytosis Impairment of IFN anti-viral response
T111 20580-20677 Sentence denotes Treatment of cytokine storm manifestations during ARDS Increased risk of secondary HZV infections
T112 20678-20782 Sentence denotes TNF-inhibitors Interference with viral penetration into the cell Slight increase in viral infection risk
T113 20783-20851 Sentence denotes NSAIDs – Facilitation of viral penetration by overexpression of ACE2
T114 20852-20891 Sentence denotes Delay in diagnosis due to fever masking
T115 20892-20943 Sentence denotes Corticosteroids – Increased risk of viral infection
T116 20944-21015 Sentence denotes Increased mortality and risk of secondary bacterial or fungal infection
T117 21016-21156 Sentence denotes ACE2 = angiotensin converting enzyme 2, ARDS = acute respiratory distress syndrome, NAK = numb-associated kinase; HZV = Herpes Zoster virus,
T118 21157-21221 Sentence denotes IFN = interferon, NSAIDs = nonsteroidal anti-inflammatory drugs.
T119 21223-21258 Sentence denotes 5.1 Chloroquine/hydroxychloroquine
T120 21259-21464 Sentence denotes Chloroquine and hydroxychloroquine are widely used anti-malarial drugs with well-known immunomodulatory properties that have extended their use to several immuno-rheumatological diseases including RA [83].
T121 21465-21565 Sentence denotes The ability of chloroquine to produce an anti-viral effect has been known since the late 1960s [84].
T122 21566-21822 Sentence denotes Several mechanisms by which the drug is able to interfere with the growth and spread of different viruses (including SARS coronavirus) have been demonstrated in in vitro studies [85], even though the subsequent in vivo experience was controversial [86,87].
T123 21823-22083 Sentence denotes At clinically admissible concentrations chloroquine is able to increase the endosomal pH required for virus/cell fusion, to inhibit the toll-like receptor activity, and to interfere with terminal glycosylation of the cellular receptor ACE 2 [[88], [89], [90]].
T124 22084-22263 Sentence denotes All these functions may negatively influence the virus-receptor binding, resulting in a potential effect of the drug on both entry and post-entry stages of the SARS CoV infection.
T125 22264-22525 Sentence denotes As a consequence, chloroquine has recently been included in at least 10 randomized controlled trials currently ongoing in China, where it is tested for the treatment of COVID-19 under various combination protocols with the anti-viral drugs mentioned above [91].
T126 22526-22830 Sentence denotes Interim results from more than 100 patients have demonstrated that chloroquine is superior to the control treatment in improving lung imaging findings, inhibiting the exacerbation of pneumonia, promoting a virus negative conversion, and shortening the disease course at different levels of severity [92].
T127 22831-22990 Sentence denotes More recently, hydroxychloroquine was demonstrated to be more 3-times more potent than chloroquine in an in vitro study based on pharmacokinetic models (PBPK).
T128 22991-23181 Sentence denotes An oral loading dose of 400 mg twice daily, followed by a maintenance dose of 200 mg given twice daily for 4 days seems to be the best option for the management of SARS-CoV-2 infection [93].
T129 23183-23210 Sentence denotes 5.2 IL-6 and IL-1 blockers
T130 23211-23454 Sentence denotes As already described, ARDS occurring in most severe case of COVID-19 infection is mainly produced by the massive release of pro-inflammatory mediators (CRS) associated with viral replication and lung injury, leading to multiorgan failure [22].
T131 23455-23629 Sentence denotes Moreover, the high levels of these cytokines have been reported to be inversely related to the absolute lymphocytes count, with surviving T-cells functionally exhausted [94].
T132 23630-23831 Sentence denotes Since an effective immune response against viral infections depends on the activation of cytotoxic T cells, CRS might be associated with a decreased viral clearance, contributing to COVID-19 worsening.
T133 23832-24015 Sentence denotes IL-6 and IL-1 play a pivotal role in this hyperinflammatory condition, suggesting the potential use of their blockers as treatment option for SARS-CoV2 related interstitial pneumonia.
T134 24016-24188 Sentence denotes Data from a phase 3 RCT of IL-1 blockade (anakinra) in sepsis showed significant survival benefit in patients with hyperinflammation, without increased adverse events [95].
T135 24189-24421 Sentence denotes A small retrospective study on 21 patients affected by severe COVID-19 demonstrated that tocilizumab improved CT scan abnormalities and oxygen saturation, and normalized CRP levels and lymphocytes count in most of the patients [96].
T136 24422-24885 Sentence denotes A multicentre RCT of tocilizumab (IL-6 receptor blocker licensed for both RA and cytokine release syndrome) has been approved in China and is currently ongoing in patients with COVID-19 pneumonia and elevated IL-6 levels (ChiCTR2000029765) and a phase II study has been approved by the Italian Regulatory Drug Agency (AIFA) and will enrol 330 patients with pneumonia and early respiratory failure, with 1-month mortality reduction as primary outcome (TOCIVID-19).
T137 24886-25048 Sentence denotes Moreover, the company that produces the second marketed IL-6 inhibitor sarilumab recently announced its intention to undertake a study with a similar design [97].
T138 25049-25191 Sentence denotes The identification of a unique definition of CRS during COVID-19 infection is crucial to better customize the management of critical patients.
T139 25192-25542 Sentence denotes The presence of a large area of lung injury (≥50%) with decreased levels of CD4 and CD8 T-lymphocytes (lower than 50% of minimum normal range), and increased levels of IL-6 in peripheral blood have been recognized as the greatest risk factors of CRS in a retrospective analysis of 11 critically pneumonia Chinese patients infected with COVID-19 [98].
T140 25543-25752 Sentence denotes Increasing ferritin level and erythrocyte sedimentation rate or decreasing platelet counts would be additional parameters potentially useful to discriminate patients requiring immunosuppressive treatment [22].
T141 25754-25773 Sentence denotes 5.3 TNF inhibitors
T142 25774-25973 Sentence denotes As previously described, SARS-CoV infection is associated with a downregulation of ACE2 expression coupled with an increased activity of the renin-angiotensin system responsible for lung injury [14].
T143 25974-26162 Sentence denotes Moreover, the viral spike protein is able to induce a TNF-α-converting enzyme (TACE)-dependent shedding of the ACE2 ectodomain, crucial for the penetration of the virus into the cell [99].
T144 26163-26377 Sentence denotes Since this process seems to be strictly coupled to TNFα production, it has been postulated that the use of TNF inhibitors may be effective in reducing both SARS-CoV2 infection and the consequent organ damage [100].
T145 26378-26530 Sentence denotes As a result, a study evaluating adalimumab in COVID-19 infection has recently been registered in the Chinese Clinical Trial Registry (ChiCTR2000030089).
T146 26532-26560 Sentence denotes 5.4 Janus kinase inhibitors
T147 26561-26672 Sentence denotes As previously described in detail, SARS-CoV-2 enters targeted cells through receptor-mediated endocytosis [12].
T148 26673-26886 Sentence denotes Some of the identified regulators of clathrin-mediated endocytosis are members of the numb-associated kinase (NAK) family, such as AP2-associated protein kinase 1 (AAK1) and cyclin G-associated kinase (GAK) [101].
T149 26887-27016 Sentence denotes Inhibition of AAK1 may stop the access of the virus into lung cells and also the intracellular assembly of virus particles [102].
T150 27017-27097 Sentence denotes Of 47 AAK1 blockers approved for medical use, 6 inhibit AAK1 with high affinity.
T151 27098-27319 Sentence denotes These include oncologic agents such as erlotinib, sunitinib, ruxolitinib, and fedratinib, which have all been demonstrated to inhibit infection of cells by Dengue virus, Ebola virus, and respiratory syncytial virus [103].
T152 27320-27538 Sentence denotes Unfortunately, all these compounds are able to produce adequate NAK inhibition only at doses significantly higher than those normally used in clinical practice and therefore potentially toxic for the patient [104,105].
T153 27539-27735 Sentence denotes Conversely, the JAK inhibitor baricitinib is able to effectively inhibit AAK1 and GAK at the plasma concentration obtained with the approved dosage for the treatment of RA (2 to 4 mg daily) [106].
T154 27736-28015 Sentence denotes Moreover, as a selective inhibitor of JAK 1 and 2, baricitinib is also able to produce an important dampening of host inflammatory response due to CRS (including IL-6 and interferon gamma) responsible for the more severe forms of interstitial pneumonia during COVID-19 [107,108].
T155 28016-28257 Sentence denotes Finally, the minimal interaction of baricitinib with the relevant CYP drug-metabolising enzymes makes the drug a possible candidate for inclusion in combination protocols with antiviral drugs such as lopinavir/ritonavir and remdesivir [109].
T156 28258-28518 Sentence denotes Interestingly, tofacitinib shows no detectable inhibition of AAK1 [104], whereas currently no data are available on the possible effect of other JAK inhibitors approved or tested for RA (such as upadacitinib or filgotinib) in relation to coronavirus infection.
T157 28519-28716 Sentence denotes Unexpectedly, the only clinical trial evaluating the potential role of clathrin-mediated endocytosis blockade in the management of COVID-19 is currently ongoing with ruxolitinib (ChiCTR2000029580).
T158 28717-28862 Sentence denotes On the other side, IFN is one of the most potent innate immune responses to prevent viral replication during the early phases of infection [110].
T159 28863-29078 Sentence denotes The activation of transcription through JAK/STAT signaling pathway by IFNs leads to the upregulation of several interferon stimulated genes which have the ability to rapidly kill viruses within infected cells [111].
T160 29079-29326 Sentence denotes Almost all viruses have developed strategies to combat the effects of type 1 and type 3 IFNs by blocking the IFN signaling pathway [112] and viral encoded factors able to antagonize the JAK/STAT pathway are crucial determinants of virulence [113].
T161 29327-29483 Sentence denotes In particular, Influenza A viruses disrupt JAK/STAT signaling by reducing the expression of the IFN receptor and by directly inhibiting IFN signaling [114].
T162 29484-29734 Sentence denotes As a consequence, JAK/STAT blockade generated by baricitinib certainly produces an impairment of IFN-mediated anti-viral response, with a potential facilitating effect on the progression of SARS-CoV2 infection at the moment not yet better quantified.
T163 29735-29991 Sentence denotes In conclusion, evidence of the possible use of baricitinib in the treatment of COVID-19 infection remains highly controversial and further studies are warranted to better clarify its potential role in the treatment of more serious cases of viral pneumonia.
T164 29993-30007 Sentence denotes 6 Conclusions
T165 30008-30146 Sentence denotes The COVID-19 epidemic represents a health emergency that is inevitably affecting the management of a complex disease such as RA [115,116].
T166 30147-30258 Sentence denotes As a chronic autoimmune inflammatory disorder, RA carries a higher infectious risk than the general population.
T167 30259-30491 Sentence denotes The use of synthetic and biologic disease-modifying drugs is associated with a potential further increase in the incidence of serious infections, but the poor control of RA disease activity is an even greater infectious risk factor.
T168 30492-30589 Sentence denotes Thus, RA patients should be encouraged to continue their treatment even during COVID-19 outbreak.
T169 30590-30779 Sentence denotes In our opinion, this strategy is reasonable as it aims to prevent disease flares that can contributes to increase patient burden, disability, poor quality of life, and healthcare use [117].
T170 30780-31037 Sentence denotes In addition, the discontinuation of ongoing treatments could lead to the need to introduce CS as bridging therapy, which may further increase the risk of viral infection, as well as being inappropriate for the management of SARS-CoV2 interstitial pneumonia.
T171 31038-31275 Sentence denotes Chloroquine and hydroxychloroquine are currently included in the treatment protocol for the management of COVID-19 infections and might be useful to prevent or mitigate the course of infection in patients with RA taking them as csDMARDs.
T172 31276-31567 Sentence denotes The use of IL-6 inhibitors as tocilizumab or sarilumab seems to be promising for the management of most critical cases of interstitial pneumonia complicated by CRS, but the identification of definite criteria to discriminate patients to be treated with these compounds is still under debate.
T173 31568-31801 Sentence denotes Finally, although baricitinib has the potential to affect SARS-CoV2 penetration into pulmonary epithelial cells, major concerns remain about the inhibition of IFNs activity which could be detrimental in the course of viral infection.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T5 1156-1158 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T1 23-43 Phenotype denotes rheumatoid arthritis http://purl.obolibrary.org/obo/HP_0001370
T2 562-582 Phenotype denotes rheumatoid arthritis http://purl.obolibrary.org/obo/HP_0001370
T3 584-586 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T4 720-739 Phenotype denotes autoimmune diseases http://purl.obolibrary.org/obo/HP_0002960
T6 1233-1235 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T7 1294-1303 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T8 1641-1650 Phenotype denotes dry cough http://purl.obolibrary.org/obo/HP_0031246
T9 1652-1657 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T10 1659-1666 Phenotype denotes dyspnea http://purl.obolibrary.org/obo/HP_0002094
T11 1671-1678 Phenotype denotes fatigue http://purl.obolibrary.org/obo/HP_0012378
T12 1695-1706 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T13 1866-1875 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T14 1940-1960 Phenotype denotes Respiratory Distress http://purl.obolibrary.org/obo/HP_0002098
T15 3175-3195 Phenotype denotes rheumatoid arthritis http://purl.obolibrary.org/obo/HP_0001370
T16 3197-3199 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T17 3401-3410 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T18 3532-3546 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T19 3994-3996 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T20 5301-5318 Phenotype denotes diabetes mellitus http://purl.obolibrary.org/obo/HP_0000819
T21 5322-5334 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T22 5868-5880 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T23 5882-5899 Phenotype denotes diabetes mellitus http://purl.obolibrary.org/obo/HP_0000819
T24 5914-5920 Phenotype denotes stroke http://purl.obolibrary.org/obo/HP_0001297
T25 6274-6300 Phenotype denotes Cytokines Release Syndrome http://purl.obolibrary.org/obo/HP_0033041
T26 6652-6657 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T27 6659-6677 Phenotype denotes hyperferritinaemia http://purl.obolibrary.org/obo/HP_0003281
T28 6983-6988 Phenotype denotes tumor http://purl.obolibrary.org/obo/HP_0002664
T29 7129-7143 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T30 7254-7256 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T31 7292-7294 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T32 7490-7499 Phenotype denotes arthritis http://purl.obolibrary.org/obo/HP_0001369
T33 7789-7791 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T34 7914-7916 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T35 7972-7981 Phenotype denotes arthritis http://purl.obolibrary.org/obo/HP_0001369
T36 8094-8096 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T37 8300-8302 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T38 8316-8318 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T39 8755-8775 Phenotype denotes autoimmune disorders http://purl.obolibrary.org/obo/HP_0002960
T40 8903-8905 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T41 9740-9742 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T42 9749-9766 Phenotype denotes Diabetes mellitus http://purl.obolibrary.org/obo/HP_0000819
T43 9768-9791 Phenotype denotes cardiovascular diseases http://purl.obolibrary.org/obo/HP_0001626
T44 9793-9806 Phenotype denotes renal failure http://purl.obolibrary.org/obo/HP_0000083
T45 9808-9833 Phenotype denotes interstitial lung disease http://purl.obolibrary.org/obo/HP_0006530
T46 9839-9876 Phenotype denotes chronic obstructive pulmonary disease http://purl.obolibrary.org/obo/HP_0006510
T47 9878-9882 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T48 9970-9972 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T49 9991-9993 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T50 10346-10348 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T51 10529-10531 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T52 10615-10617 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T53 10734-10751 Phenotype denotes severe infections http://purl.obolibrary.org/obo/HP_0032169
T54 10931-10933 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T55 11045-11047 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T56 11189-11191 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T57 11990-12013 Phenotype denotes diffuse alveolar damage http://purl.obolibrary.org/obo/HP_0033006
T58 13482-13487 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T59 13745-13747 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T60 13833-13835 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T61 14757-14759 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T62 15331-15353 Phenotype denotes respiratory infections http://purl.obolibrary.org/obo/HP_0011947
T63 16015-16039 Phenotype denotes opportunistic infections http://purl.obolibrary.org/obo/HP_0031690
T64 16087-16089 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T65 16501-16503 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T66 19786-19788 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T67 20276-20290 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T68 20408-20417 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T69 20593-20607 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T70 20878-20883 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T71 21069-21089 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T72 21456-21458 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T73 22709-22718 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T74 24005-24014 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T75 24071-24077 Phenotype denotes sepsis http://purl.obolibrary.org/obo/HP_0100806
T76 24496-24498 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T77 24503-24528 Phenotype denotes cytokine release syndrome http://purl.obolibrary.org/obo/HP_0033041
T78 24608-24617 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T79 24779-24788 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T80 24799-24818 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878
T81 25487-25496 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T82 25543-25562 Phenotype denotes Increasing ferritin http://purl.obolibrary.org/obo/HP_0003281
T83 27708-27710 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T84 27979-27988 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T85 28441-28443 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T86 29981-29990 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T87 30133-30135 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T88 30194-30196 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T89 30429-30431 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T90 30498-30500 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T91 31027-31036 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T92 31248-31250 Phenotype denotes RA http://purl.obolibrary.org/obo/HP_0001370
T93 31411-31420 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090

2_test

Id Subject Object Predicate Lexical cue
32205186-32015507-4826866 1467-1468 32015507 denotes 1
32205186-25172238-4826867 3008-3009 25172238 denotes 9
32205186-24800825-4826868 5221-5223 24800825 denotes 14
32205186-24290661-4826869 6596-6598 24290661 denotes 19
32205186-26836913-4826870 6781-6783 26836913 denotes 20
32205186-26096095-4826871 7674-7676 26096095 denotes 23
32205186-23266520-4826872 7677-7679 23266520 denotes 24
32205186-29259607-4826873 7793-7795 29259607 denotes 25
32205186-31470887-4826874 7918-7920 31470887 denotes 26
32205186-23192911-4826875 8057-8059 23192911 denotes 27
32205186-20675706-4826876 8063-8065 20675706 denotes 28
32205186-12355475-4826877 8456-8458 12355475 denotes 30
32205186-16984941-4826878 8655-8657 16984941 denotes 31
32205186-21288960-4826879 9198-9200 21288960 denotes 32
32205186-24095940-4826880 9744-9746 24095940 denotes 34
32205186-23192911-4826881 9974-9976 23192911 denotes 27
32205186-23813577-4826882 9977-9979 23813577 denotes 35
32205186-31396235-4826883 10663-10665 31396235 denotes 37
32205186-23192911-4826884 10840-10842 23192911 denotes 27
32205186-17870034-4826885 10843-10845 17870034 denotes 38
32205186-9251634-4826886 10945-10947 9251634 denotes 39
32205186-22393128-4826887 10957-10959 22393128 denotes 41
32205186-21884589-4826888 11113-11115 21884589 denotes 42
32205186-16195357-4826889 11765-11767 16195357 denotes 43
32205186-30917856-4826890 12554-12556 30917856 denotes 47
32205186-25896805-4826891 13239-13241 25896805 denotes 50
32205186-18668604-4826892 13885-13887 18668604 denotes 51
32205186-18260176-4826893 14433-14435 18260176 denotes 52
32205186-23192911-4826894 14879-14881 23192911 denotes 27
32205186-29180125-4826895 14882-14884 29180125 denotes 54
32205186-28298374-4826896 14924-14926 28298374 denotes 55
32205186-19022409-4826897 14965-14967 19022409 denotes 56
32205186-22796281-4826898 14971-14973 22796281 denotes 57
32205186-29592917-4826899 14977-14979 29592917 denotes 58
32205186-25975452-4826900 15152-15154 25975452 denotes 59
32205186-23800448-4826901 15304-15306 23800448 denotes 61
32205186-23256105-4826902 15715-15717 23256105 denotes 62
32205186-31733368-4826903 16138-16140 31733368 denotes 65
32205186-30219772-4826904 16686-16688 30219772 denotes 68
32205186-27113415-4826905 16898-16900 27113415 denotes 69
32205186-30183607-4826906 17194-17196 30183607 denotes 71
32205186-31692920-4826907 17439-17441 31692920 denotes 72
32205186-31520803-4826908 17442-17444 31520803 denotes 73
32205186-28250461-4826909 17701-17703 28250461 denotes 74
32205186-26868298-4826910 18657-18659 26868298 denotes 76
32205186-32020029-4826911 19116-19118 32020029 denotes 80
32205186-30938227-4826912 19505-19507 30938227 denotes 81
32205186-32034323-4826913 21460-21462 32034323 denotes 83
32205186-4306296-4826914 21561-21563 4306296 denotes 84
32205186-21550310-4826915 21815-21817 21550310 denotes 86
32205186-16115318-4826916 22066-22068 16115318 denotes 88
32205186-16439323-4826917 22078-22080 16439323 denotes 90
32205186-26584195-4826918 24184-24186 26584195 denotes 95
32205186-24800825-4826919 25969-25971 24800825 denotes 14
32205186-18490652-4826920 26158-26160 18490652 denotes 99
32205186-17532082-4826921 26372-26375 17532082 denotes 100
32205186-28240606-4826922 27314-27317 28240606 denotes 103
32205186-29753658-4826923 27533-27536 29753658 denotes 105
32205186-29545548-4826924 28006-28009 29545548 denotes 107
32205186-29649002-4826925 28010-28013 29649002 denotes 108
32205186-18049472-4826926 28857-28860 18049472 denotes 110
32205186-31059844-4826927 30137-30140 31059844 denotes 115
32205186-29037899-4826928 30141-30144 29037899 denotes 116
32205186-31639516-4826929 30774-30777 31639516 denotes 117