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PMC:7102583 / 64-1358 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
28 213-221 Species denotes patients Tax:9606
29 345-358 Species denotes coronaviruses Tax:11118
30 846-854 Species denotes patients Tax:9606
31 1016-1024 Species denotes patients Tax:9606
32 1199-1207 Species denotes patients Tax:9606
33 47-56 Chemical denotes melatonin MESH:D008550
34 667-676 Chemical denotes Melatonin MESH:D008550
35 806-815 Chemical denotes Melatonin MESH:D008550
36 1035-1044 Chemical denotes melatonin MESH:D008550
37 1111-1120 Chemical denotes melatonin MESH:D008550
38 79-87 Disease denotes COVID-19 MESH:C000657245
39 147-155 Disease denotes COVID-19 MESH:C000657245
40 204-212 Disease denotes infected MESH:D007239
41 288-308 Disease denotes respiratory disorder MESH:D012131
42 416-428 Disease denotes inflammation MESH:D007249
43 502-510 Disease denotes COVID-19 MESH:C000657245
44 583-600 Disease denotes acute lung injury MESH:D055371
45 607-642 Disease denotes acute respiratory distress syndrome MESH:D012128
46 644-648 Disease denotes ARDS MESH:D012128
47 660-665 Disease denotes death MESH:D003643
48 764-768 Disease denotes ARDS MESH:D012128
49 888-895 Disease denotes anxiety MESH:D001007
50 1007-1015 Disease denotes COVID-19 MESH:C000657245
51 1190-1198 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T2 47-56 Body_part denotes melatonin http://purl.org/sig/ont/fma/fma74644
T3 538-546 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T4 589-593 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T5 667-676 Body_part denotes Melatonin http://purl.org/sig/ont/fma/fma74644
T6 806-815 Body_part denotes Melatonin http://purl.org/sig/ont/fma/fma74644
T7 1035-1044 Body_part denotes melatonin http://purl.org/sig/ont/fma/fma74644
T8 1111-1120 Body_part denotes melatonin http://purl.org/sig/ont/fma/fma74644

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 589-593 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T2 867-873 Body_part denotes vessel http://purl.obolibrary.org/obo/UBERON_0000055

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T2 79-87 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T3 147-155 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T4 288-308 Disease denotes respiratory disorder http://purl.obolibrary.org/obo/MONDO_0005087
T5 416-428 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T6 502-510 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T7 583-600 Disease denotes acute lung injury http://purl.obolibrary.org/obo/MONDO_0006502|http://purl.obolibrary.org/obo/MONDO_0015796
T9 594-600 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T10 602-605 Disease denotes ALI http://purl.obolibrary.org/obo/MONDO_0006502
T11 607-642 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T12 613-642 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T13 644-648 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T14 760-763 Disease denotes ALI http://purl.obolibrary.org/obo/MONDO_0006502
T15 764-768 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T16 888-895 Disease denotes anxiety http://purl.obolibrary.org/obo/MONDO_0005618|http://purl.obolibrary.org/obo/MONDO_0011918
T18 1007-1015 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T19 1190-1198 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T2 156-159 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T3 167-168 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T4 536-537 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T5 589-593 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T6 589-593 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T7 678-679 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T8 867-873 http://purl.obolibrary.org/obo/UBERON_0000055 denotes vessel
T9 1045-1048 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T10 1049-1050 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T11 1128-1133 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T3 47-56 Chemical denotes melatonin http://purl.obolibrary.org/obo/CHEBI_16796
T4 667-676 Chemical denotes Melatonin http://purl.obolibrary.org/obo/CHEBI_16796
T5 728-736 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T6 806-815 Chemical denotes Melatonin http://purl.obolibrary.org/obo/CHEBI_16796
T7 1035-1044 Chemical denotes melatonin http://purl.obolibrary.org/obo/CHEBI_16796
T8 1111-1120 Chemical denotes melatonin http://purl.obolibrary.org/obo/CHEBI_16796

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 110-122 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T2 266-278 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T3 416-428 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T4 460-475 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T4 0-123 Sentence denotes This article summarizes the likely benefits of melatonin in the attenuation of COVID-19 based on its putative pathogenesis.
T5 124-222 Sentence denotes The recent outbreak of COVID-19 has become a pandemic with tens of thousands of infected patients.
T6 223-521 Sentence denotes Based on clinical features, pathology, the pathogenesis of acute respiratory disorder induced by either highly homogenous coronaviruses or other pathogens, the evidence suggests that excessive inflammation, oxidation, and an exaggerated immune response very likely contribute to COVID-19 pathology.
T7 522-666 Sentence denotes This leads to a cytokine storm and subsequent progression to acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) and often death.
T8 667-805 Sentence denotes Melatonin, a well-known anti-inflammatory and anti-oxidative molecule, is protective against ALI/ARDS caused by viral and other pathogens.
T9 806-1025 Sentence denotes Melatonin is effective in critical care patients by reducing vessel permeability, anxiety, sedation use, and improving sleeping quality, which might also be beneficial for better clinical outcomes for COVID-19 patients.
T10 1026-1071 Sentence denotes Notably, melatonin has a high safety profile.
T11 1072-1208 Sentence denotes There is significant data showing that melatonin limits virus-related diseases and would also likely be beneficial in COVID-19 patients.
T12 1209-1294 Sentence denotes Additional experiments and clinical studies are required to confirm this speculation.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 538-552 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T2 583-600 Phenotype denotes acute lung injury http://www.orpha.net/ORDO/Orphanet_178320
T3 602-605 Phenotype denotes ALI http://www.orpha.net/ORDO/Orphanet_178320
T4 613-633 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T5 760-763 Phenotype denotes ALI http://www.orpha.net/ORDO/Orphanet_178320
T6 888-895 Phenotype denotes anxiety http://purl.obolibrary.org/obo/HP_0000739