PMC:7102583 / 19765-20326 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7102583","sourcedb":"PMC","sourceid":"7102583","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7102583","text":"The possible beneficial effects of melatonin as adjuvant use in COVID-19 in anti-inflammation, anti-oxidation, immune response regulation has been repeatedly demonstrated in respiratory disorder models induced by infections and associated complications. Melatonin has a high safety profile. Although the direct evidence of melatonin application in COVID-19 is unclear, both its use in experimental animal models and in studies on humans has continuously documented its efficacy and safety and its use by COVID-19 patients predictably would be highly beneficial.","tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"813","span":{"begin":430,"end":436},"obj":"Species"},{"id":"814","span":{"begin":513,"end":521},"obj":"Species"},{"id":"815","span":{"begin":35,"end":44},"obj":"Chemical"},{"id":"816","span":{"begin":254,"end":263},"obj":"Chemical"},{"id":"817","span":{"begin":323,"end":332},"obj":"Chemical"},{"id":"818","span":{"begin":64,"end":72},"obj":"Disease"},{"id":"819","span":{"begin":81,"end":93},"obj":"Disease"},{"id":"820","span":{"begin":174,"end":194},"obj":"Disease"},{"id":"821","span":{"begin":213,"end":223},"obj":"Disease"},{"id":"822","span":{"begin":348,"end":356},"obj":"Disease"},{"id":"823","span":{"begin":504,"end":512},"obj":"Disease"}],"attributes":[{"id":"A813","pred":"tao:has_database_id","subj":"813","obj":"Tax:9606"},{"id":"A814","pred":"tao:has_database_id","subj":"814","obj":"Tax:9606"},{"id":"A815","pred":"tao:has_database_id","subj":"815","obj":"MESH:D008550"},{"id":"A816","pred":"tao:has_database_id","subj":"816","obj":"MESH:D008550"},{"id":"A817","pred":"tao:has_database_id","subj":"817","obj":"MESH:D008550"},{"id":"A818","pred":"tao:has_database_id","subj":"818","obj":"MESH:C000657245"},{"id":"A819","pred":"tao:has_database_id","subj":"819","obj":"MESH:D007249"},{"id":"A820","pred":"tao:has_database_id","subj":"820","obj":"MESH:D012131"},{"id":"A821","pred":"tao:has_database_id","subj":"821","obj":"MESH:D007239"},{"id":"A822","pred":"tao:has_database_id","subj":"822","obj":"MESH:C000657245"},{"id":"A823","pred":"tao:has_database_id","subj":"823","obj":"MESH:C000657245"},{"subj":"813","pred":"source","obj":"LitCovid-PubTator"},{"subj":"814","pred":"source","obj":"LitCovid-PubTator"},{"subj":"815","pred":"source","obj":"LitCovid-PubTator"},{"subj":"816","pred":"source","obj":"LitCovid-PubTator"},{"subj":"817","pred":"source","obj":"LitCovid-PubTator"},{"subj":"818","pred":"source","obj":"LitCovid-PubTator"},{"subj":"819","pred":"source","obj":"LitCovid-PubTator"},{"subj":"820","pred":"source","obj":"LitCovid-PubTator"},{"subj":"821","pred":"source","obj":"LitCovid-PubTator"},{"subj":"822","pred":"source","obj":"LitCovid-PubTator"},{"subj":"823","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T214","span":{"begin":35,"end":44},"obj":"Body_part"},{"id":"T215","span":{"begin":254,"end":263},"obj":"Body_part"},{"id":"T216","span":{"begin":323,"end":332},"obj":"Body_part"}],"attributes":[{"id":"A214","pred":"fma_id","subj":"T214","obj":"http://purl.org/sig/ont/fma/fma74644"},{"id":"A215","pred":"fma_id","subj":"T215","obj":"http://purl.org/sig/ont/fma/fma74644"},{"id":"A216","pred":"fma_id","subj":"T216","obj":"http://purl.org/sig/ont/fma/fma74644"},{"subj":"T214","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T215","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T216","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T199","span":{"begin":64,"end":72},"obj":"Disease"},{"id":"T200","span":{"begin":81,"end":93},"obj":"Disease"},{"id":"T201","span":{"begin":174,"end":194},"obj":"Disease"},{"id":"T202","span":{"begin":213,"end":223},"obj":"Disease"},{"id":"T203","span":{"begin":348,"end":356},"obj":"Disease"},{"id":"T204","span":{"begin":504,"end":512},"obj":"Disease"}],"attributes":[{"id":"A199","pred":"mondo_id","subj":"T199","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A200","pred":"mondo_id","subj":"T200","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"},{"id":"A201","pred":"mondo_id","subj":"T201","obj":"http://purl.obolibrary.org/obo/MONDO_0005087"},{"id":"A202","pred":"mondo_id","subj":"T202","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A203","pred":"mondo_id","subj":"T203","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A204","pred":"mondo_id","subj":"T204","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"subj":"T199","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T200","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T201","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T202","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T203","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T204","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T252","span":{"begin":138,"end":141},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T253","span":{"begin":264,"end":267},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T254","span":{"begin":268,"end":269},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T255","span":{"begin":398,"end":404},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_33208"},{"id":"T256","span":{"begin":430,"end":436},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T257","span":{"begin":437,"end":440},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"}],"attributes":[{"subj":"T252","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T253","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T254","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T255","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T256","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T257","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T193","span":{"begin":35,"end":44},"obj":"Chemical"},{"id":"T194","span":{"begin":48,"end":56},"obj":"Chemical"},{"id":"T195","span":{"begin":254,"end":263},"obj":"Chemical"},{"id":"T196","span":{"begin":323,"end":332},"obj":"Chemical"},{"id":"T197","span":{"begin":333,"end":344},"obj":"Chemical"}],"attributes":[{"id":"A193","pred":"chebi_id","subj":"T193","obj":"http://purl.obolibrary.org/obo/CHEBI_16796"},{"id":"A194","pred":"chebi_id","subj":"T194","obj":"http://purl.obolibrary.org/obo/CHEBI_60809"},{"id":"A195","pred":"chebi_id","subj":"T195","obj":"http://purl.obolibrary.org/obo/CHEBI_16796"},{"id":"A196","pred":"chebi_id","subj":"T196","obj":"http://purl.obolibrary.org/obo/CHEBI_16796"},{"id":"A197","pred":"chebi_id","subj":"T197","obj":"http://purl.obolibrary.org/obo/CHEBI_33232"},{"subj":"T193","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T194","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T195","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T196","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T197","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T81","span":{"begin":81,"end":93},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T82","span":{"begin":111,"end":126},"obj":"http://purl.obolibrary.org/obo/GO_0006955"},{"id":"T83","span":{"begin":127,"end":137},"obj":"http://purl.obolibrary.org/obo/GO_0065007"}],"attributes":[{"subj":"T81","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T82","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T83","pred":"source","obj":"LitCovid-PD-GO-BP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T133","span":{"begin":0,"end":253},"obj":"Sentence"},{"id":"T134","span":{"begin":254,"end":290},"obj":"Sentence"},{"id":"T135","span":{"begin":291,"end":561},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T133","pred":"source","obj":"LitCovid-sentences"},{"subj":"T134","pred":"source","obj":"LitCovid-sentences"},{"subj":"T135","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#d793ec","default":true},{"id":"LitCovid-PD-FMA-UBERON","color":"#93ecbd"},{"id":"LitCovid-PD-MONDO","color":"#eca393"},{"id":"LitCovid-PD-CLO","color":"#939cec"},{"id":"LitCovid-PD-CHEBI","color":"#b6ec93"},{"id":"LitCovid-PD-GO-BP","color":"#ec93d0"},{"id":"LitCovid-sentences","color":"#93eaec"}]}]}}