PMC:7100515 / 8655-12701
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T74 | 141-146 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T75 | 237-245 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T76 | 300-304 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T77 | 492-497 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T78 | 574-579 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T79 | 692-697 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T80 | 860-865 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T81 | 880-888 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T82 | 1005-1012 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T83 | 1089-1094 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T84 | 1181-1186 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T85 | 1260-1265 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T86 | 1361-1366 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T87 | 1450-1455 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T88 | 1606-1613 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T89 | 1643-1650 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T90 | 1661-1666 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T91 | 1703-1710 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T92 | 1811-1818 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T93 | 1875-1882 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T94 | 1948-1955 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T95 | 1991-1998 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T96 | 2135-2143 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T97 | 2221-2228 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T98 | 2262-2267 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T99 | 2666-2670 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T100 | 2678-2683 | Body_part | denotes | Cells | http://purl.org/sig/ont/fma/fma68646 |
| T101 | 2941-2951 | Body_part | denotes | fibroblast | http://purl.org/sig/ont/fma/fma63877 |
| T102 | 2967-2972 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T103 | 3036-3041 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T104 | 3107-3112 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T105 | 3334-3342 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T106 | 3369-3374 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T107 | 3424-3432 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T108 | 3518-3526 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
| T109 | 3528-3533 | Body_part | denotes | Cells | http://purl.org/sig/ont/fma/fma68646 |
| T110 | 3810-3815 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T111 | 3817-3822 | Body_part | denotes | Cells | http://purl.org/sig/ont/fma/fma68646 |
LitCovid_AGAC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| p43953s18 | 449-457 | PosReg | denotes | increase |
| p43953s20 | 461-471 | Enzyme | denotes | luciferase |
| p43953s21 | 472-482 | MPA | denotes | activities |
| p43954s13 | 616-626 | Enzyme | denotes | luciferase |
| p43954s14 | 627-637 | MPA | denotes | activities |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T77 | 29-37 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T78 | 68-76 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T79 | 398-406 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T80 | 521-529 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T81 | 657-665 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T82 | 714-722 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T83 | 749-757 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T84 | 897-905 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T85 | 912-920 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T86 | 992-1000 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T87 | 1036-1044 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T88 | 1241-1249 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T89 | 1412-1420 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T90 | 1482-1490 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T91 | 1552-1560 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T92 | 1593-1601 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T93 | 1690-1698 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T94 | 1798-1806 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T95 | 1864-1872 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T96 | 1935-1943 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T97 | 1980-1988 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T98 | 2052-2060 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T99 | 2168-2176 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T100 | 2278-2286 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T101 | 2534-2542 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T102 | 2545-2554 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T103 | 2585-2593 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T104 | 2626-2634 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T105 | 2734-2742 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T106 | 2754-2762 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T107 | 2903-2905 | Disease | denotes | RS | http://purl.obolibrary.org/obo/MONDO_0010725 |
| T108 | 3071-3079 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T109 | 3306-3314 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T110 | 3321-3329 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T111 | 3398-3406 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T112 | 3411-3419 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T113 | 3635-3643 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T114 | 3685-3693 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T115 | 3697-3705 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T115 | 0-5 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | Human |
| T116 | 14-15 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T117 | 118-123 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T118 | 125-131 | http://purl.obolibrary.org/obo/NCBITaxon_9479 | denotes | monkey |
| T119 | 137-140 | http://purl.obolibrary.org/obo/NCBITaxon_9397 | denotes | bat |
| T120 | 141-146 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T121 | 180-181 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T122 | 263-264 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T123 | 300-310 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cell types |
| T124 | 367-369 | http://purl.obolibrary.org/obo/CLO_0001236 | denotes | 2a |
| T125 | 472-482 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
| T126 | 486-497 | http://purl.obolibrary.org/obo/CLO_0051840 | denotes | Calu3 cells |
| T127 | 486-497 | http://purl.obolibrary.org/obo/CLO_0051841 | denotes | Calu3 cells |
| T128 | 486-497 | http://purl.obolibrary.org/obo/CLO_0051842 | denotes | Calu3 cells |
| T129 | 486-497 | http://purl.obolibrary.org/obo/CLO_0051843 | denotes | Calu3 cells |
| T130 | 486-497 | http://purl.obolibrary.org/obo/CLO_0051844 | denotes | Calu3 cells |
| T131 | 486-491 | http://purl.obolibrary.org/obo/CLO_0002192 | denotes | Calu3 |
| T132 | 502-503 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T133 | 552-554 | http://purl.obolibrary.org/obo/CLO_0001236 | denotes | 2a |
| T134 | 557-561 | http://purl.obolibrary.org/obo/CLO_0009989 | denotes | Huh7 |
| T135 | 566-570 | http://purl.obolibrary.org/obo/CLO_0009524 | denotes | Vero |
| T136 | 566-570 | http://purl.obolibrary.org/obo/CLO_0050515 | denotes | Vero |
| T137 | 574-579 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T138 | 627-637 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
| T139 | 692-697 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T140 | 782-784 | http://purl.obolibrary.org/obo/CLO_0001236 | denotes | 2a |
| T141 | 838-843 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T142 | 860-865 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T143 | 1089-1094 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T144 | 1113-1118 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T145 | 1161-1166 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T146 | 1177-1180 | http://purl.obolibrary.org/obo/CLO_0001230 | denotes | 293 |
| T147 | 1177-1180 | http://purl.obolibrary.org/obo/CLO_0037237 | denotes | 293 |
| T148 | 1177-1180 | http://purl.obolibrary.org/obo/CLO_0050903 | denotes | 293 |
| T149 | 1177-1180 | http://purl.obolibrary.org/obo/CLO_0054249 | denotes | 293 |
| T150 | 1177-1180 | http://purl.obolibrary.org/obo/CLO_0054250 | denotes | 293 |
| T151 | 1177-1180 | http://purl.obolibrary.org/obo/CLO_0054251 | denotes | 293 |
| T152 | 1177-1180 | http://purl.obolibrary.org/obo/CLO_0054252 | denotes | 293 |
| T153 | 1181-1186 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T154 | 1212-1215 | http://purl.obolibrary.org/obo/CLO_0001230 | denotes | 293 |
| T155 | 1212-1215 | http://purl.obolibrary.org/obo/CLO_0037237 | denotes | 293 |
| T156 | 1212-1215 | http://purl.obolibrary.org/obo/CLO_0050903 | denotes | 293 |
| T157 | 1212-1215 | http://purl.obolibrary.org/obo/CLO_0054249 | denotes | 293 |
| T158 | 1212-1215 | http://purl.obolibrary.org/obo/CLO_0054250 | denotes | 293 |
| T159 | 1212-1215 | http://purl.obolibrary.org/obo/CLO_0054251 | denotes | 293 |
| T160 | 1212-1215 | http://purl.obolibrary.org/obo/CLO_0054252 | denotes | 293 |
| T161 | 1255-1265 | http://purl.obolibrary.org/obo/CLO_0054283 | denotes | HeLa cells |
| T162 | 1255-1265 | http://purl.obolibrary.org/obo/CLO_0054285 | denotes | HeLa cells |
| T163 | 1255-1265 | http://purl.obolibrary.org/obo/CLO_0054286 | denotes | HeLa cells |
| T164 | 1255-1265 | http://purl.obolibrary.org/obo/CLO_0054287 | denotes | HeLa cells |
| T165 | 1255-1265 | http://purl.obolibrary.org/obo/CLO_0054288 | denotes | HeLa cells |
| T166 | 1255-1265 | http://purl.obolibrary.org/obo/CLO_0054289 | denotes | HeLa cells |
| T167 | 1255-1259 | http://purl.obolibrary.org/obo/CLO_0003684 | denotes | HeLa |
| T168 | 1255-1259 | http://purl.obolibrary.org/obo/CLO_0050910 | denotes | HeLa |
| T169 | 1291-1295 | http://purl.obolibrary.org/obo/CLO_0003684 | denotes | HeLa |
| T170 | 1291-1295 | http://purl.obolibrary.org/obo/CLO_0050910 | denotes | HeLa |
| T171 | 1350-1354 | http://purl.obolibrary.org/obo/CLO_0003684 | denotes | HeLa |
| T172 | 1350-1354 | http://purl.obolibrary.org/obo/CLO_0050910 | denotes | HeLa |
| T173 | 1361-1366 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T174 | 1440-1443 | http://purl.obolibrary.org/obo/CLO_0001230 | denotes | 293 |
| T175 | 1440-1443 | http://purl.obolibrary.org/obo/CLO_0037237 | denotes | 293 |
| T176 | 1440-1443 | http://purl.obolibrary.org/obo/CLO_0050903 | denotes | 293 |
| T177 | 1440-1443 | http://purl.obolibrary.org/obo/CLO_0054249 | denotes | 293 |
| T178 | 1440-1443 | http://purl.obolibrary.org/obo/CLO_0054250 | denotes | 293 |
| T179 | 1440-1443 | http://purl.obolibrary.org/obo/CLO_0054251 | denotes | 293 |
| T180 | 1440-1443 | http://purl.obolibrary.org/obo/CLO_0054252 | denotes | 293 |
| T181 | 1450-1455 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T182 | 1656-1660 | http://purl.obolibrary.org/obo/CLO_0050894 | denotes | 293T |
| T183 | 1656-1660 | http://purl.obolibrary.org/obo/CLO_0051650 | denotes | 293T |
| T184 | 1656-1660 | http://purl.obolibrary.org/obo/CLO_0052052 | denotes | 293T |
| T185 | 1661-1666 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T186 | 1845-1846 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T187 | 2215-2220 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T188 | 2252-2255 | http://purl.obolibrary.org/obo/CLO_0001230 | denotes | 293 |
| T189 | 2252-2255 | http://purl.obolibrary.org/obo/CLO_0037237 | denotes | 293 |
| T190 | 2252-2255 | http://purl.obolibrary.org/obo/CLO_0050903 | denotes | 293 |
| T191 | 2252-2255 | http://purl.obolibrary.org/obo/CLO_0054249 | denotes | 293 |
| T192 | 2252-2255 | http://purl.obolibrary.org/obo/CLO_0054250 | denotes | 293 |
| T193 | 2252-2255 | http://purl.obolibrary.org/obo/CLO_0054251 | denotes | 293 |
| T194 | 2252-2255 | http://purl.obolibrary.org/obo/CLO_0054252 | denotes | 293 |
| T195 | 2262-2267 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T196 | 2502-2503 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T197 | 2612-2613 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T198 | 2615-2616 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | b |
| T199 | 2666-2676 | http://purl.obolibrary.org/obo/CLO_0000031 | denotes | cell lines |
| T200 | 2678-2683 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | Cells |
| T201 | 2689-2694 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T202 | 2699-2705 | http://purl.obolibrary.org/obo/NCBITaxon_33208 | denotes | animal |
| T203 | 2807-2809 | http://purl.obolibrary.org/obo/CLO_0001382 | denotes | 48 |
| T204 | 2891-2901 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
| T205 | 2903-2905 | http://purl.obolibrary.org/obo/CLO_0008882 | denotes | RS |
| T206 | 2927-2930 | http://purl.obolibrary.org/obo/NCBITaxon_9397 | denotes | bat |
| T207 | 2941-2951 | http://purl.obolibrary.org/obo/CL_0000057 | denotes | fibroblast |
| T208 | 2967-2972 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T209 | 3021-3024 | http://purl.obolibrary.org/obo/CLO_0001230 | denotes | 293 |
| T210 | 3021-3024 | http://purl.obolibrary.org/obo/CLO_0037237 | denotes | 293 |
| T211 | 3021-3024 | http://purl.obolibrary.org/obo/CLO_0050903 | denotes | 293 |
| T212 | 3021-3024 | http://purl.obolibrary.org/obo/CLO_0054249 | denotes | 293 |
| T213 | 3021-3024 | http://purl.obolibrary.org/obo/CLO_0054250 | denotes | 293 |
| T214 | 3021-3024 | http://purl.obolibrary.org/obo/CLO_0054251 | denotes | 293 |
| T215 | 3021-3024 | http://purl.obolibrary.org/obo/CLO_0054252 | denotes | 293 |
| T216 | 3032-3035 | http://purl.obolibrary.org/obo/CLO_0001230 | denotes | 293 |
| T217 | 3032-3035 | http://purl.obolibrary.org/obo/CLO_0037237 | denotes | 293 |
| T218 | 3032-3035 | http://purl.obolibrary.org/obo/CLO_0050903 | denotes | 293 |
| T219 | 3032-3035 | http://purl.obolibrary.org/obo/CLO_0054249 | denotes | 293 |
| T220 | 3032-3035 | http://purl.obolibrary.org/obo/CLO_0054250 | denotes | 293 |
| T221 | 3032-3035 | http://purl.obolibrary.org/obo/CLO_0054251 | denotes | 293 |
| T222 | 3032-3035 | http://purl.obolibrary.org/obo/CLO_0054252 | denotes | 293 |
| T223 | 3036-3041 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T224 | 3090-3094 | http://purl.obolibrary.org/obo/CLO_0003684 | denotes | HeLa |
| T225 | 3090-3094 | http://purl.obolibrary.org/obo/CLO_0050910 | denotes | HeLa |
| T226 | 3102-3112 | http://purl.obolibrary.org/obo/CLO_0054283 | denotes | HeLa cells |
| T227 | 3102-3112 | http://purl.obolibrary.org/obo/CLO_0054285 | denotes | HeLa cells |
| T228 | 3102-3112 | http://purl.obolibrary.org/obo/CLO_0054286 | denotes | HeLa cells |
| T229 | 3102-3112 | http://purl.obolibrary.org/obo/CLO_0054287 | denotes | HeLa cells |
| T230 | 3102-3112 | http://purl.obolibrary.org/obo/CLO_0054288 | denotes | HeLa cells |
| T231 | 3102-3112 | http://purl.obolibrary.org/obo/CLO_0054289 | denotes | HeLa cells |
| T232 | 3102-3106 | http://purl.obolibrary.org/obo/CLO_0003684 | denotes | HeLa |
| T233 | 3102-3106 | http://purl.obolibrary.org/obo/CLO_0050910 | denotes | HeLa |
| T234 | 3369-3374 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T235 | 3502-3506 | http://purl.obolibrary.org/obo/NCBITaxon_9925 | denotes | goat |
| T236 | 3528-3533 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | Cells |
| T237 | 3800-3803 | http://purl.obolibrary.org/obo/CLO_0001230 | denotes | 293 |
| T238 | 3800-3803 | http://purl.obolibrary.org/obo/CLO_0037237 | denotes | 293 |
| T239 | 3800-3803 | http://purl.obolibrary.org/obo/CLO_0050903 | denotes | 293 |
| T240 | 3800-3803 | http://purl.obolibrary.org/obo/CLO_0054249 | denotes | 293 |
| T241 | 3800-3803 | http://purl.obolibrary.org/obo/CLO_0054250 | denotes | 293 |
| T242 | 3800-3803 | http://purl.obolibrary.org/obo/CLO_0054251 | denotes | 293 |
| T243 | 3800-3803 | http://purl.obolibrary.org/obo/CLO_0054252 | denotes | 293 |
| T244 | 3810-3815 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T245 | 3817-3822 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | Cells |
| T246 | 4027-4028 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T90 | 237-245 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T91 | 880-888 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T92 | 1005-1012 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T93 | 1606-1613 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T94 | 1643-1650 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T95 | 1703-1710 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T96 | 1811-1818 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T97 | 1875-1882 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T98 | 1948-1955 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T99 | 1991-1998 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T100 | 2135-2143 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T101 | 2221-2228 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T102 | 2229-2236 | Chemical | denotes | mixture | http://purl.obolibrary.org/obo/CHEBI_60004 |
| T103 | 2516-2525 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T104 | 2903-2905 | Chemical | denotes | RS | http://purl.obolibrary.org/obo/CHEBI_73819 |
| T105 | 3334-3342 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T106 | 3424-3432 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T107 | 3778-3785 | Chemical | denotes | mixture | http://purl.obolibrary.org/obo/CHEBI_60004 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T9 | 669-681 | http://purl.obolibrary.org/obo/GO_0009293 | denotes | Transduction |
| T10 | 1396-1408 | http://purl.obolibrary.org/obo/GO_0009293 | denotes | transduction |
| T11 | 2830-2842 | http://purl.obolibrary.org/obo/GO_0009293 | denotes | transduction |
| T12 | 3861-3873 | http://purl.obolibrary.org/obo/GO_0009293 | denotes | transduction |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T60 | 0-39 | Sentence | denotes | Human ACE2 is a receptor for SARS-CoV-2 |
| T61 | 40-147 | Sentence | denotes | Next, we determined whether SARS-CoV-2 S pseudovirions were able to transduce human, monkey, and bat cells. |
| T62 | 148-282 | Sentence | denotes | VSV-G pseudovirons were used as a positive control, whereas bald particles with no spike proteins (mock) served as a negative control. |
| T63 | 283-371 | Sentence | denotes | As expected, all cell types were effectively transduced by VSV-G pseudovirons (Fig. 2a). |
| T64 | 372-556 | Sentence | denotes | Compared to mock control, SARS-CoV-2 S pseudovirions showed an over 500-fold increase in luciferase activities in Calu3 cells, at a level similar to SARS-CoV S pseudovirions (Fig. 2a). |
| T65 | 557-668 | Sentence | denotes | Huh7 and Vero 81 cells also gave about 10-fold increase in luciferase activities when transduced by SARS-CoV-2. |
| T66 | 669-921 | Sentence | denotes | Transduction of LLCMK2 cells was higher with SARS-CoV S pseudovirions than with SARS-CoV-2 S pseudovirions (Fig. 2a), suggesting that there might be some differences on virus entry on LLCMK2 cells mediated by S proteins between SARS-CoV-2 and SARS-CoV. |
| T67 | 922-1031 | Sentence | denotes | We then investigated whether any known CoV receptors might be used by SARS-CoV-2 S protein as entry receptor. |
| T68 | 1032-1330 | Sentence | denotes | The SARS-CoV-2 S pseudovirons were used to transduce BHK cells stably expressing human aminopeptidase N (hAPN), the receptor for human CoV 229E, 293 cells stably expressing hACE2 (293/hACE2), the receptor for SARS-CoV, and HeLa cells stably expressing hDPP4 (HeLa/hDPP4), the receptor for MERS-CoV. |
| T69 | 1331-1565 | Sentence | denotes | While BHK/hAPN and HeLa/hDPP4 cells were not susceptible for the transduction of SARS-CoV-2 S pseudovirions, 293/hACE2 cells were highly transduced by SARS-CoV-2 S pseudovirions, consistent with hACE2 as the receptor for SARS-CoV-213. |
| T70 | 1566-1651 | Sentence | denotes | We then determined whether SARS-CoV-2 S protein could directly bind to hACE2 protein. |
| T71 | 1652-1776 | Sentence | denotes | HEK 293T cells transiently expressing SARS-CoV-2 S protein were incubated with soluble hACE2 and analyzed by flow cytometry. |
| T72 | 1777-1999 | Sentence | denotes | As shown in Fig. 2c, SARS-CoV-2 S protein bound to soluble hACE2 at a level similar to SARS-CoV S protein, although the mean fluorescence intensity (MFI) for SARS-CoV-2 S protein was slightly lower than SARS-CoV S protein. |
| T73 | 2000-2120 | Sentence | denotes | To further investigate if hACE2 is the receptor for SARS-CoV-2, we performed inhibition experiments using soluble hACE2. |
| T74 | 2121-2268 | Sentence | denotes | Soluble hACE2 proteins were pre-incubated with SARS-CoV-2 S pseudovirons on ice for 1 h, then virus-protein mixture was added onto 293/hACE2 cells. |
| T75 | 2269-2555 | Sentence | denotes | Entry of SARS-CoV-2 S pseudovirions was significantly prevented by pre-incubation of soluble hACE2 at both 10 μg/ml and 50 μg/ml (Fig. 2d), further supporting the notion that hACE2 is the receptor and soluble hACE2 might be used as a therapeutic inhibitor against SARS-CoV-2 infection. |
| T76 | 2556-2611 | Sentence | denotes | Fig. 2 Entry and receptor of SARS-CoV-2 S pseudovirons. |
| T77 | 2612-2677 | Sentence | denotes | a, b Entry of SARS-CoV-2 S pseudovirions on indicated cell lines. |
| T78 | 2678-2803 | Sentence | denotes | Cells from human and animal origin were inoculated with SARS-CoV-2 S (red), SARS-CoV S (blue), or VSV-G (gray) pseudovirions. |
| T79 | 2804-2902 | Sentence | denotes | At 48 h post inoculation, transduction efficiency was measured according to luciferase activities. |
| T80 | 2903-3160 | Sentence | denotes | RS, Rhinolophus sinicus bat embryonic fibroblast; BHK/hAPN, BHK cells stably expressing hAPN, the hCoV-229E receptor; 293/hACE2, 293 cells stably expressing hACE2, the SARS-CoV receptor; HeLa/hDPP4, HeLa cells stably expressing hDPP4, the MERS-CoV receptor. |
| T81 | 3161-3232 | Sentence | denotes | Experiments were done in triplicates and repeated at least three times. |
| T82 | 3233-3360 | Sentence | denotes | One representative is shown with error bars indicating SEM. c Binding of SARS-CoV S and SARS-CoV-2 S proteins to soluble hACE2. |
| T83 | 3361-3527 | Sentence | denotes | HEK293T cells transiently expressing SARS-CoV and SARS-CoV-2 S proteins were incubated with the soluble hACE2 on ice, followed by polyclonal goat anti-hACE2 antibody. |
| T84 | 3528-3566 | Sentence | denotes | Cells were analyzed by flow cytometry. |
| T85 | 3567-3684 | Sentence | denotes | The experiments were repeated at least three times. d Inhibition of SARS-CoV-2 S pseudovirion entry by soluble hACE2. |
| T86 | 3685-3816 | Sentence | denotes | SARS-CoV S, SARS-CoV-2 S, or VSV-G pseudovirions were pre-incubated with soluble hACE2, then mixture were added to 293/hACE2 cells. |
| T87 | 3817-3887 | Sentence | denotes | Cells were lysed 40 h later and pseudoviral transduction was measured. |
| T88 | 3888-3948 | Sentence | denotes | Experiments were done twice and one representative is shown. |
| T89 | 3949-3998 | Sentence | denotes | Error bars indicate SEM of technical triplicates. |
| T90 | 3999-4046 | Sentence | denotes | Source data are provided as a Source Data file. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 328 | 6-10 | Gene | denotes | ACE2 | Gene:59272 |
| 329 | 0-5 | Species | denotes | Human | Tax:9606 |
| 332 | 2596-2597 | Gene | denotes | S | Gene:43740568 |
| 333 | 2585-2595 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 370 | 2957-2961 | Gene | denotes | hAPN | Gene:290 |
| 371 | 2991-2995 | Gene | denotes | hAPN | Gene:290 |
| 372 | 3025-3030 | Gene | denotes | hACE2 | Gene:59272 |
| 373 | 3060-3065 | Gene | denotes | hACE2 | Gene:59272 |
| 374 | 3095-3100 | Gene | denotes | hDPP4 | Gene:1803 |
| 375 | 3131-3136 | Gene | denotes | hDPP4 | Gene:1803 |
| 376 | 3354-3359 | Gene | denotes | hACE2 | Gene:59272 |
| 377 | 3465-3470 | Gene | denotes | hACE2 | Gene:59272 |
| 378 | 3512-3517 | Gene | denotes | hACE2 | Gene:59272 |
| 379 | 3678-3683 | Gene | denotes | hACE2 | Gene:59272 |
| 380 | 3766-3771 | Gene | denotes | hACE2 | Gene:59272 |
| 381 | 3804-3809 | Gene | denotes | hACE2 | Gene:59272 |
| 382 | 3708-3709 | Gene | denotes | S | Gene:43740568 |
| 383 | 3646-3647 | Gene | denotes | S | Gene:43740568 |
| 384 | 3422-3423 | Gene | denotes | S | Gene:43740568 |
| 385 | 3332-3333 | Gene | denotes | S | Gene:43740568 |
| 386 | 2745-2746 | Gene | denotes | S | Gene:43740568 |
| 387 | 2637-2638 | Gene | denotes | S | Gene:43740568 |
| 388 | 2626-2636 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 389 | 2689-2694 | Species | denotes | human | Tax:9606 |
| 390 | 2734-2744 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 391 | 2754-2762 | Species | denotes | SARS-CoV | Tax:694009 |
| 392 | 2907-2926 | Species | denotes | Rhinolophus sinicus | Tax:89399 |
| 393 | 3071-3079 | Species | denotes | SARS-CoV | Tax:694009 |
| 394 | 3142-3150 | Species | denotes | MERS-CoV | Tax:1335626 |
| 395 | 3306-3314 | Species | denotes | SARS-CoV | Tax:694009 |
| 396 | 3321-3331 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 397 | 3398-3406 | Species | denotes | SARS-CoV | Tax:694009 |
| 398 | 3411-3421 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 399 | 3635-3645 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 400 | 3685-3693 | Species | denotes | SARS-CoV | Tax:694009 |
| 401 | 3697-3707 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 402 | 3032-3041 | CellLine | denotes | 293 cells | CVCL:0045 |
| 403 | 3090-3094 | CellLine | denotes | HeLa | CVCL:0030 |
| 404 | 3102-3106 | CellLine | denotes | HeLa | CVCL:0030 |
| 405 | 3361-3368 | CellLine | denotes | HEK293T | CVCL:0063 |
| 477 | 231-236 | Gene | denotes | spike | Gene:43740568 |
| 478 | 1119-1135 | Gene | denotes | aminopeptidase N | Gene:290 |
| 479 | 1137-1141 | Gene | denotes | hAPN | Gene:290 |
| 480 | 1205-1210 | Gene | denotes | hACE2 | Gene:59272 |
| 481 | 1216-1221 | Gene | denotes | hACE2 | Gene:59272 |
| 482 | 1284-1289 | Gene | denotes | hDPP4 | Gene:1803 |
| 483 | 1296-1301 | Gene | denotes | hDPP4 | Gene:1803 |
| 484 | 1341-1345 | Gene | denotes | hAPN | Gene:290 |
| 485 | 1444-1449 | Gene | denotes | hACE2 | Gene:59272 |
| 486 | 1526-1531 | Gene | denotes | hACE2 | Gene:59272 |
| 487 | 1637-1642 | Gene | denotes | hACE2 | Gene:59272 |
| 488 | 1739-1744 | Gene | denotes | hACE2 | Gene:59272 |
| 489 | 1836-1841 | Gene | denotes | hACE2 | Gene:59272 |
| 490 | 2026-2031 | Gene | denotes | hACE2 | Gene:59272 |
| 491 | 2114-2119 | Gene | denotes | hACE2 | Gene:59272 |
| 492 | 2129-2134 | Gene | denotes | hACE2 | Gene:59272 |
| 493 | 2256-2261 | Gene | denotes | hACE2 | Gene:59272 |
| 494 | 2362-2367 | Gene | denotes | hACE2 | Gene:59272 |
| 495 | 2445-2450 | Gene | denotes | hACE2 | Gene:59272 |
| 496 | 2479-2484 | Gene | denotes | hACE2 | Gene:59272 |
| 497 | 1355-1360 | Gene | denotes | hDPP4 | Gene:1803 |
| 498 | 2289-2290 | Gene | denotes | S | Gene:43740568 |
| 499 | 2179-2180 | Gene | denotes | S | Gene:43740568 |
| 500 | 1946-1947 | Gene | denotes | S | Gene:43740568 |
| 501 | 1809-1810 | Gene | denotes | S | Gene:43740568 |
| 502 | 1701-1702 | Gene | denotes | S | Gene:43740568 |
| 503 | 1604-1605 | Gene | denotes | S | Gene:43740568 |
| 504 | 1493-1494 | Gene | denotes | S | Gene:43740568 |
| 505 | 1423-1424 | Gene | denotes | S | Gene:43740568 |
| 506 | 1047-1048 | Gene | denotes | S | Gene:43740568 |
| 507 | 1003-1004 | Gene | denotes | S | Gene:43740568 |
| 508 | 760-761 | Gene | denotes | S | Gene:43740568 |
| 509 | 409-410 | Gene | denotes | S | Gene:43740568 |
| 510 | 79-80 | Gene | denotes | S | Gene:43740568 |
| 511 | 68-78 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 512 | 118-123 | Species | denotes | human | Tax:9606 |
| 513 | 398-408 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 514 | 521-529 | Species | denotes | SARS-CoV | Tax:694009 |
| 515 | 657-667 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 516 | 714-722 | Species | denotes | SARS-CoV | Tax:694009 |
| 517 | 749-759 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 518 | 897-907 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 519 | 912-920 | Species | denotes | SARS-CoV | Tax:694009 |
| 520 | 961-964 | Species | denotes | CoV | Tax:11118 |
| 521 | 992-1002 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 522 | 1036-1046 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 523 | 1113-1118 | Species | denotes | human | Tax:9606 |
| 524 | 1161-1166 | Species | denotes | human | Tax:9606 |
| 525 | 1167-1170 | Species | denotes | CoV | Tax:11118 |
| 526 | 1241-1249 | Species | denotes | SARS-CoV | Tax:694009 |
| 527 | 1321-1329 | Species | denotes | MERS-CoV | Tax:1335626 |
| 528 | 1412-1422 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 529 | 1482-1492 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 530 | 1552-1562 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 531 | 1593-1603 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 532 | 1690-1700 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 533 | 1798-1808 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 534 | 1864-1872 | Species | denotes | SARS-CoV | Tax:694009 |
| 535 | 1935-1945 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 536 | 1980-1988 | Species | denotes | SARS-CoV | Tax:694009 |
| 537 | 2052-2062 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 538 | 2168-2178 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 539 | 2278-2288 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 540 | 1171-1175 | Species | denotes | 229E | Tax:11137 |
| 541 | 2539-2554 | Disease | denotes | CoV-2 infection | MESH:C000657245 |
| 542 | 557-561 | CellLine | denotes | Huh7 | CVCL:0336 |
| 543 | 1177-1186 | CellLine | denotes | 293 cells | CVCL:0045 |
| 544 | 1255-1259 | CellLine | denotes | HeLa | CVCL:0030 |
| 545 | 1291-1295 | CellLine | denotes | HeLa | CVCL:0030 |
| 546 | 1350-1354 | CellLine | denotes | HeLa | CVCL:0030 |
| 547 | 1652-1660 | CellLine | denotes | HEK 293T | CVCL:0063 |