PMC:7100515 / 37388-38742 JSONTXT

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    LitCovid-PD-FMA-UBERON

    {"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T329","span":{"begin":0,"end":10},"obj":"Body_part"},{"id":"T330","span":{"begin":41,"end":49},"obj":"Body_part"},{"id":"T331","span":{"begin":421,"end":429},"obj":"Body_part"},{"id":"T332","span":{"begin":650,"end":658},"obj":"Body_part"},{"id":"T333","span":{"begin":707,"end":715},"obj":"Body_part"},{"id":"T334","span":{"begin":757,"end":760},"obj":"Body_part"},{"id":"T335","span":{"begin":763,"end":766},"obj":"Body_part"},{"id":"T336","span":{"begin":771,"end":779},"obj":"Body_part"},{"id":"T337","span":{"begin":887,"end":895},"obj":"Body_part"},{"id":"T338","span":{"begin":984,"end":992},"obj":"Body_part"},{"id":"T339","span":{"begin":1046,"end":1049},"obj":"Body_part"},{"id":"T340","span":{"begin":1082,"end":1085},"obj":"Body_part"},{"id":"T341","span":{"begin":1123,"end":1126},"obj":"Body_part"},{"id":"T342","span":{"begin":1252,"end":1255},"obj":"Body_part"},{"id":"T343","span":{"begin":1300,"end":1303},"obj":"Body_part"}],"attributes":[{"id":"A329","pred":"fma_id","subj":"T329","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A330","pred":"fma_id","subj":"T330","obj":"http://purl.org/sig/ont/fma/fma82751"},{"id":"A331","pred":"fma_id","subj":"T331","obj":"http://purl.org/sig/ont/fma/fma67180"},{"id":"A332","pred":"fma_id","subj":"T332","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A333","pred":"fma_id","subj":"T333","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A334","pred":"fma_id","subj":"T334","obj":"http://purl.org/sig/ont/fma/fma278683"},{"id":"A335","pred":"fma_id","subj":"T335","obj":"http://purl.org/sig/ont/fma/fma63011"},{"id":"A336","pred":"fma_id","subj":"T336","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A337","pred":"fma_id","subj":"T337","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A338","pred":"fma_id","subj":"T338","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A339","pred":"fma_id","subj":"T339","obj":"http://purl.org/sig/ont/fma/fma62872"},{"id":"A340","pred":"fma_id","subj":"T340","obj":"http://purl.org/sig/ont/fma/fma62872"},{"id":"A341","pred":"fma_id","subj":"T341","obj":"http://purl.org/sig/ont/fma/fma62872"},{"id":"A342","pred":"fma_id","subj":"T342","obj":"http://purl.org/sig/ont/fma/fma62872"},{"id":"A343","pred":"fma_id","subj":"T343","obj":"http://purl.org/sig/ont/fma/fma62872"}],"text":"Antibodies and inhibitors\nBroad-spectrum cysteine protease inhibitor E64D (#HY-100229), Cathepsin L-specific inhibitor SID 26681509 (#HY-103353), Cathepsin B-specific inhibitor CA-074 (#HY-103350), PIKfyve inhibitors apilimod (#HY-14644) and YM201636 (#HY-13228), were purchased from Med Chem Express (MCE, New Jersey, USA). Calcium channel blocker tetrandrine (#S2403) was purchased from Selleck Chemicals (Texas, USA). Endosome acidification inhibitors NH4Cl (#A9434) and bafilomycin A (#19-148) were purchased from Sigma-Aldrich (St. Louis, MO, USA). Rabbit polyclonal against SARS S1 antibodies (#40150-T62), mouse monoclonal against MERS-CoV S2 antibody (#40070-MM11), mouse monoclonal against SARS S1 antibody (#40150-MM02), rabbit polyclonal against HIV-1 Gag-p24 antibody (11695-RP01) were purchased from Sino Biological Inc. (Beijing, China). Goat polyclonal against human ACE2 antibody (#AF933) was purchased from R\u0026D Systems (Minnesota, USA). Mouse monoclonal anti-FLAG M2 antibody was purchased from Sigma-Aldrich. Donkey Anti-Rabbit IgG (#711-035-152), Goat Anti-Mouse IgG (#115-035-146), and Rabbit Anti-Goat IgG (#305-035-003) were purchased from Jackson ImmunoResearch (West Grove, PA, USA). Alexa Fluor 488-conjugated goat anti-rabbit IgG, Alexa Fluor 488-conjugated goat anti-mouse IgG were purchased from ZSGB-Bio LLC (Beijing, China)."}

    LitCovid-PD-MONDO

    {"project":"LitCovid-PD-MONDO","denotations":[{"id":"T345","span":{"begin":580,"end":584},"obj":"Disease"},{"id":"T346","span":{"begin":699,"end":703},"obj":"Disease"}],"attributes":[{"id":"A345","pred":"mondo_id","subj":"T345","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A346","pred":"mondo_id","subj":"T346","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Antibodies and inhibitors\nBroad-spectrum cysteine protease inhibitor E64D (#HY-100229), Cathepsin L-specific inhibitor SID 26681509 (#HY-103353), Cathepsin B-specific inhibitor CA-074 (#HY-103350), PIKfyve inhibitors apilimod (#HY-14644) and YM201636 (#HY-13228), were purchased from Med Chem Express (MCE, New Jersey, USA). Calcium channel blocker tetrandrine (#S2403) was purchased from Selleck Chemicals (Texas, USA). Endosome acidification inhibitors NH4Cl (#A9434) and bafilomycin A (#19-148) were purchased from Sigma-Aldrich (St. Louis, MO, USA). Rabbit polyclonal against SARS S1 antibodies (#40150-T62), mouse monoclonal against MERS-CoV S2 antibody (#40070-MM11), mouse monoclonal against SARS S1 antibody (#40150-MM02), rabbit polyclonal against HIV-1 Gag-p24 antibody (11695-RP01) were purchased from Sino Biological Inc. (Beijing, China). Goat polyclonal against human ACE2 antibody (#AF933) was purchased from R\u0026D Systems (Minnesota, USA). Mouse monoclonal anti-FLAG M2 antibody was purchased from Sigma-Aldrich. Donkey Anti-Rabbit IgG (#711-035-152), Goat Anti-Mouse IgG (#115-035-146), and Rabbit Anti-Goat IgG (#305-035-003) were purchased from Jackson ImmunoResearch (West Grove, PA, USA). Alexa Fluor 488-conjugated goat anti-rabbit IgG, Alexa Fluor 488-conjugated goat anti-mouse IgG were purchased from ZSGB-Bio LLC (Beijing, China)."}

    LitCovid-PD-CLO

    {"project":"LitCovid-PD-CLO","denotations":[{"id":"T851","span":{"begin":156,"end":157},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T852","span":{"begin":486,"end":487},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T853","span":{"begin":493,"end":496},"obj":"http://purl.obolibrary.org/obo/CLO_0001079"},{"id":"T854","span":{"begin":533,"end":535},"obj":"http://purl.obolibrary.org/obo/CLO_0009141"},{"id":"T855","span":{"begin":533,"end":535},"obj":"http://purl.obolibrary.org/obo/CLO_0050980"},{"id":"T856","span":{"begin":544,"end":546},"obj":"http://purl.obolibrary.org/obo/CLO_0007815"},{"id":"T857","span":{"begin":585,"end":587},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"},{"id":"T858","span":{"begin":613,"end":618},"obj":"http://purl.obolibrary.org/obo/CLO_0007836"},{"id":"T859","span":{"begin":647,"end":649},"obj":"http://purl.obolibrary.org/obo/CLO_0008922"},{"id":"T860","span":{"begin":647,"end":649},"obj":"http://purl.obolibrary.org/obo/CLO_0050052"},{"id":"T861","span":{"begin":674,"end":679},"obj":"http://purl.obolibrary.org/obo/CLO_0007836"},{"id":"T862","span":{"begin":704,"end":706},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"},{"id":"T863","span":{"begin":852,"end":856},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9925"},{"id":"T864","span":{"begin":876,"end":881},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T865","span":{"begin":924,"end":927},"obj":"http://purl.obolibrary.org/obo/CLO_0008693"},{"id":"T866","span":{"begin":924,"end":927},"obj":"http://purl.obolibrary.org/obo/CLO_0008770"},{"id":"T867","span":{"begin":954,"end":959},"obj":"http://purl.obolibrary.org/obo/CLO_0007836"},{"id":"T868","span":{"begin":1027,"end":1033},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9793"},{"id":"T869","span":{"begin":1066,"end":1070},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9925"},{"id":"T870","span":{"begin":1076,"end":1081},"obj":"http://purl.obolibrary.org/obo/CLO_0007836"},{"id":"T871","span":{"begin":1118,"end":1122},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9925"},{"id":"T872","span":{"begin":1235,"end":1239},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9925"},{"id":"T873","span":{"begin":1284,"end":1288},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9925"},{"id":"T874","span":{"begin":1294,"end":1299},"obj":"http://purl.obolibrary.org/obo/CLO_0007836"},{"id":"T875","span":{"begin":1333,"end":1336},"obj":"http://purl.obolibrary.org/obo/CLO_0050167"}],"text":"Antibodies and inhibitors\nBroad-spectrum cysteine protease inhibitor E64D (#HY-100229), Cathepsin L-specific inhibitor SID 26681509 (#HY-103353), Cathepsin B-specific inhibitor CA-074 (#HY-103350), PIKfyve inhibitors apilimod (#HY-14644) and YM201636 (#HY-13228), were purchased from Med Chem Express (MCE, New Jersey, USA). Calcium channel blocker tetrandrine (#S2403) was purchased from Selleck Chemicals (Texas, USA). Endosome acidification inhibitors NH4Cl (#A9434) and bafilomycin A (#19-148) were purchased from Sigma-Aldrich (St. Louis, MO, USA). Rabbit polyclonal against SARS S1 antibodies (#40150-T62), mouse monoclonal against MERS-CoV S2 antibody (#40070-MM11), mouse monoclonal against SARS S1 antibody (#40150-MM02), rabbit polyclonal against HIV-1 Gag-p24 antibody (11695-RP01) were purchased from Sino Biological Inc. (Beijing, China). Goat polyclonal against human ACE2 antibody (#AF933) was purchased from R\u0026D Systems (Minnesota, USA). Mouse monoclonal anti-FLAG M2 antibody was purchased from Sigma-Aldrich. Donkey Anti-Rabbit IgG (#711-035-152), Goat Anti-Mouse IgG (#115-035-146), and Rabbit Anti-Goat IgG (#305-035-003) were purchased from Jackson ImmunoResearch (West Grove, PA, USA). Alexa Fluor 488-conjugated goat anti-rabbit IgG, Alexa Fluor 488-conjugated goat anti-mouse IgG were purchased from ZSGB-Bio LLC (Beijing, China)."}

    LitCovid-PD-CHEBI

    {"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T300","span":{"begin":15,"end":25},"obj":"Chemical"},{"id":"T301","span":{"begin":41,"end":68},"obj":"Chemical"},{"id":"T302","span":{"begin":41,"end":49},"obj":"Chemical"},{"id":"T303","span":{"begin":50,"end":68},"obj":"Chemical"},{"id":"T305","span":{"begin":59,"end":68},"obj":"Chemical"},{"id":"T306","span":{"begin":76,"end":78},"obj":"Chemical"},{"id":"T307","span":{"begin":109,"end":118},"obj":"Chemical"},{"id":"T308","span":{"begin":134,"end":136},"obj":"Chemical"},{"id":"T309","span":{"begin":167,"end":176},"obj":"Chemical"},{"id":"T310","span":{"begin":186,"end":188},"obj":"Chemical"},{"id":"T311","span":{"begin":206,"end":216},"obj":"Chemical"},{"id":"T312","span":{"begin":228,"end":230},"obj":"Chemical"},{"id":"T313","span":{"begin":253,"end":255},"obj":"Chemical"},{"id":"T314","span":{"begin":325,"end":348},"obj":"Chemical"},{"id":"T315","span":{"begin":325,"end":332},"obj":"Chemical"},{"id":"T316","span":{"begin":444,"end":454},"obj":"Chemical"},{"id":"T317","span":{"begin":455,"end":460},"obj":"Chemical"},{"id":"T318","span":{"begin":647,"end":649},"obj":"Chemical"},{"id":"T319","span":{"begin":981,"end":983},"obj":"Chemical"},{"id":"T321","span":{"begin":1198,"end":1200},"obj":"Chemical"},{"id":"T326","span":{"begin":1208,"end":1223},"obj":"Chemical"},{"id":"T327","span":{"begin":1214,"end":1219},"obj":"Chemical"},{"id":"T328","span":{"begin":1257,"end":1272},"obj":"Chemical"},{"id":"T329","span":{"begin":1263,"end":1268},"obj":"Chemical"}],"attributes":[{"id":"A300","pred":"chebi_id","subj":"T300","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A301","pred":"chebi_id","subj":"T301","obj":"http://purl.obolibrary.org/obo/CHEBI_64152"},{"id":"A302","pred":"chebi_id","subj":"T302","obj":"http://purl.obolibrary.org/obo/CHEBI_15356"},{"id":"A303","pred":"chebi_id","subj":"T303","obj":"http://purl.obolibrary.org/obo/CHEBI_37670"},{"id":"A304","pred":"chebi_id","subj":"T303","obj":"http://purl.obolibrary.org/obo/CHEBI_60258"},{"id":"A305","pred":"chebi_id","subj":"T305","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A306","pred":"chebi_id","subj":"T306","obj":"http://purl.obolibrary.org/obo/CHEBI_74059"},{"id":"A307","pred":"chebi_id","subj":"T307","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A308","pred":"chebi_id","subj":"T308","obj":"http://purl.obolibrary.org/obo/CHEBI_74059"},{"id":"A309","pred":"chebi_id","subj":"T309","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A310","pred":"chebi_id","subj":"T310","obj":"http://purl.obolibrary.org/obo/CHEBI_74059"},{"id":"A311","pred":"chebi_id","subj":"T311","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A312","pred":"chebi_id","subj":"T312","obj":"http://purl.obolibrary.org/obo/CHEBI_74059"},{"id":"A313","pred":"chebi_id","subj":"T313","obj":"http://purl.obolibrary.org/obo/CHEBI_74059"},{"id":"A314","pred":"chebi_id","subj":"T314","obj":"http://purl.obolibrary.org/obo/CHEBI_38215"},{"id":"A315","pred":"chebi_id","subj":"T315","obj":"http://purl.obolibrary.org/obo/CHEBI_22984"},{"id":"A316","pred":"chebi_id","subj":"T316","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A317","pred":"chebi_id","subj":"T317","obj":"http://purl.obolibrary.org/obo/CHEBI_31206"},{"id":"A318","pred":"chebi_id","subj":"T318","obj":"http://purl.obolibrary.org/obo/CHEBI_29387"},{"id":"A319","pred":"chebi_id","subj":"T319","obj":"http://purl.obolibrary.org/obo/CHEBI_34827"},{"id":"A320","pred":"chebi_id","subj":"T319","obj":"http://purl.obolibrary.org/obo/CHEBI_51112"},{"id":"A321","pred":"chebi_id","subj":"T321","obj":"http://purl.obolibrary.org/obo/CHEBI_30745"},{"id":"A322","pred":"chebi_id","subj":"T321","obj":"http://purl.obolibrary.org/obo/CHEBI_30768"},{"id":"A323","pred":"chebi_id","subj":"T321","obj":"http://purl.obolibrary.org/obo/CHEBI_74753"},{"id":"A324","pred":"chebi_id","subj":"T321","obj":"http://purl.obolibrary.org/obo/CHEBI_7959"},{"id":"A325","pred":"chebi_id","subj":"T321","obj":"http://purl.obolibrary.org/obo/CHEBI_8429"},{"id":"A326","pred":"chebi_id","subj":"T326","obj":"http://purl.obolibrary.org/obo/CHEBI_52661"},{"id":"A327","pred":"chebi_id","subj":"T327","obj":"http://purl.obolibrary.org/obo/CHEBI_24061"},{"id":"A328","pred":"chebi_id","subj":"T328","obj":"http://purl.obolibrary.org/obo/CHEBI_52661"},{"id":"A329","pred":"chebi_id","subj":"T329","obj":"http://purl.obolibrary.org/obo/CHEBI_24061"}],"text":"Antibodies and inhibitors\nBroad-spectrum cysteine protease inhibitor E64D (#HY-100229), Cathepsin L-specific inhibitor SID 26681509 (#HY-103353), Cathepsin B-specific inhibitor CA-074 (#HY-103350), PIKfyve inhibitors apilimod (#HY-14644) and YM201636 (#HY-13228), were purchased from Med Chem Express (MCE, New Jersey, USA). Calcium channel blocker tetrandrine (#S2403) was purchased from Selleck Chemicals (Texas, USA). Endosome acidification inhibitors NH4Cl (#A9434) and bafilomycin A (#19-148) were purchased from Sigma-Aldrich (St. Louis, MO, USA). Rabbit polyclonal against SARS S1 antibodies (#40150-T62), mouse monoclonal against MERS-CoV S2 antibody (#40070-MM11), mouse monoclonal against SARS S1 antibody (#40150-MM02), rabbit polyclonal against HIV-1 Gag-p24 antibody (11695-RP01) were purchased from Sino Biological Inc. (Beijing, China). Goat polyclonal against human ACE2 antibody (#AF933) was purchased from R\u0026D Systems (Minnesota, USA). Mouse monoclonal anti-FLAG M2 antibody was purchased from Sigma-Aldrich. Donkey Anti-Rabbit IgG (#711-035-152), Goat Anti-Mouse IgG (#115-035-146), and Rabbit Anti-Goat IgG (#305-035-003) were purchased from Jackson ImmunoResearch (West Grove, PA, USA). Alexa Fluor 488-conjugated goat anti-rabbit IgG, Alexa Fluor 488-conjugated goat anti-mouse IgG were purchased from ZSGB-Bio LLC (Beijing, China)."}

    LitCovid-PD-GO-BP

    {"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T77","span":{"begin":430,"end":443},"obj":"http://purl.obolibrary.org/obo/GO_0045851"}],"text":"Antibodies and inhibitors\nBroad-spectrum cysteine protease inhibitor E64D (#HY-100229), Cathepsin L-specific inhibitor SID 26681509 (#HY-103353), Cathepsin B-specific inhibitor CA-074 (#HY-103350), PIKfyve inhibitors apilimod (#HY-14644) and YM201636 (#HY-13228), were purchased from Med Chem Express (MCE, New Jersey, USA). Calcium channel blocker tetrandrine (#S2403) was purchased from Selleck Chemicals (Texas, USA). Endosome acidification inhibitors NH4Cl (#A9434) and bafilomycin A (#19-148) were purchased from Sigma-Aldrich (St. Louis, MO, USA). Rabbit polyclonal against SARS S1 antibodies (#40150-T62), mouse monoclonal against MERS-CoV S2 antibody (#40070-MM11), mouse monoclonal against SARS S1 antibody (#40150-MM02), rabbit polyclonal against HIV-1 Gag-p24 antibody (11695-RP01) were purchased from Sino Biological Inc. (Beijing, China). Goat polyclonal against human ACE2 antibody (#AF933) was purchased from R\u0026D Systems (Minnesota, USA). Mouse monoclonal anti-FLAG M2 antibody was purchased from Sigma-Aldrich. Donkey Anti-Rabbit IgG (#711-035-152), Goat Anti-Mouse IgG (#115-035-146), and Rabbit Anti-Goat IgG (#305-035-003) were purchased from Jackson ImmunoResearch (West Grove, PA, USA). Alexa Fluor 488-conjugated goat anti-rabbit IgG, Alexa Fluor 488-conjugated goat anti-mouse IgG were purchased from ZSGB-Bio LLC (Beijing, China)."}

    LitCovid-sentences

    {"project":"LitCovid-sentences","denotations":[{"id":"T269","span":{"begin":0,"end":25},"obj":"Sentence"},{"id":"T270","span":{"begin":26,"end":324},"obj":"Sentence"},{"id":"T271","span":{"begin":325,"end":420},"obj":"Sentence"},{"id":"T272","span":{"begin":421,"end":553},"obj":"Sentence"},{"id":"T273","span":{"begin":554,"end":851},"obj":"Sentence"},{"id":"T274","span":{"begin":852,"end":953},"obj":"Sentence"},{"id":"T275","span":{"begin":954,"end":1026},"obj":"Sentence"},{"id":"T276","span":{"begin":1027,"end":1207},"obj":"Sentence"},{"id":"T277","span":{"begin":1208,"end":1354},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Antibodies and inhibitors\nBroad-spectrum cysteine protease inhibitor E64D (#HY-100229), Cathepsin L-specific inhibitor SID 26681509 (#HY-103353), Cathepsin B-specific inhibitor CA-074 (#HY-103350), PIKfyve inhibitors apilimod (#HY-14644) and YM201636 (#HY-13228), were purchased from Med Chem Express (MCE, New Jersey, USA). Calcium channel blocker tetrandrine (#S2403) was purchased from Selleck Chemicals (Texas, USA). Endosome acidification inhibitors NH4Cl (#A9434) and bafilomycin A (#19-148) were purchased from Sigma-Aldrich (St. Louis, MO, USA). Rabbit polyclonal against SARS S1 antibodies (#40150-T62), mouse monoclonal against MERS-CoV S2 antibody (#40070-MM11), mouse monoclonal against SARS S1 antibody (#40150-MM02), rabbit polyclonal against HIV-1 Gag-p24 antibody (11695-RP01) were purchased from Sino Biological Inc. (Beijing, China). Goat polyclonal against human ACE2 antibody (#AF933) was purchased from R\u0026D Systems (Minnesota, USA). Mouse monoclonal anti-FLAG M2 antibody was purchased from Sigma-Aldrich. Donkey Anti-Rabbit IgG (#711-035-152), Goat Anti-Mouse IgG (#115-035-146), and Rabbit Anti-Goat IgG (#305-035-003) were purchased from Jackson ImmunoResearch (West Grove, PA, USA). Alexa Fluor 488-conjugated goat anti-rabbit IgG, Alexa Fluor 488-conjugated goat anti-mouse IgG were purchased from ZSGB-Bio LLC (Beijing, China)."}

    LitCovid-PubTator

    {"project":"LitCovid-PubTator","denotations":[{"id":"1567","span":{"begin":88,"end":99},"obj":"Gene"},{"id":"1568","span":{"begin":146,"end":157},"obj":"Gene"},{"id":"1569","span":{"begin":763,"end":766},"obj":"Gene"},{"id":"1570","span":{"begin":767,"end":770},"obj":"Gene"},{"id":"1571","span":{"begin":882,"end":886},"obj":"Gene"},{"id":"1572","span":{"begin":757,"end":762},"obj":"Species"},{"id":"1573","span":{"begin":613,"end":618},"obj":"Species"},{"id":"1574","span":{"begin":638,"end":646},"obj":"Species"},{"id":"1575","span":{"begin":674,"end":679},"obj":"Species"},{"id":"1576","span":{"begin":876,"end":881},"obj":"Species"},{"id":"1577","span":{"begin":954,"end":959},"obj":"Species"},{"id":"1578","span":{"begin":1076,"end":1081},"obj":"Species"},{"id":"1579","span":{"begin":1294,"end":1299},"obj":"Species"},{"id":"1580","span":{"begin":325,"end":332},"obj":"Chemical"},{"id":"1581","span":{"begin":349,"end":360},"obj":"Chemical"},{"id":"1582","span":{"begin":455,"end":460},"obj":"Chemical"},{"id":"1583","span":{"begin":474,"end":487},"obj":"Chemical"},{"id":"1584","span":{"begin":1208,"end":1223},"obj":"Chemical"},{"id":"1585","span":{"begin":1257,"end":1272},"obj":"Chemical"}],"attributes":[{"id":"A1567","pred":"tao:has_database_id","subj":"1567","obj":"Gene:1514"},{"id":"A1568","pred":"tao:has_database_id","subj":"1568","obj":"Gene:1508"},{"id":"A1569","pred":"tao:has_database_id","subj":"1569","obj":"Gene:155030"},{"id":"A1570","pred":"tao:has_database_id","subj":"1570","obj":"Gene:140767"},{"id":"A1571","pred":"tao:has_database_id","subj":"1571","obj":"Gene:59272"},{"id":"A1572","pred":"tao:has_database_id","subj":"1572","obj":"Tax:11676"},{"id":"A1573","pred":"tao:has_database_id","subj":"1573","obj":"Tax:10090"},{"id":"A1574","pred":"tao:has_database_id","subj":"1574","obj":"Tax:1335626"},{"id":"A1575","pred":"tao:has_database_id","subj":"1575","obj":"Tax:10090"},{"id":"A1576","pred":"tao:has_database_id","subj":"1576","obj":"Tax:9606"},{"id":"A1577","pred":"tao:has_database_id","subj":"1577","obj":"Tax:10090"},{"id":"A1578","pred":"tao:has_database_id","subj":"1578","obj":"Tax:10090"},{"id":"A1579","pred":"tao:has_database_id","subj":"1579","obj":"Tax:10090"},{"id":"A1580","pred":"tao:has_database_id","subj":"1580","obj":"MESH:D002118"},{"id":"A1581","pred":"tao:has_database_id","subj":"1581","obj":"MESH:C009438"},{"id":"A1583","pred":"tao:has_database_id","subj":"1583","obj":"MESH:C057620"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Antibodies and inhibitors\nBroad-spectrum cysteine protease inhibitor E64D (#HY-100229), Cathepsin L-specific inhibitor SID 26681509 (#HY-103353), Cathepsin B-specific inhibitor CA-074 (#HY-103350), PIKfyve inhibitors apilimod (#HY-14644) and YM201636 (#HY-13228), were purchased from Med Chem Express (MCE, New Jersey, USA). Calcium channel blocker tetrandrine (#S2403) was purchased from Selleck Chemicals (Texas, USA). Endosome acidification inhibitors NH4Cl (#A9434) and bafilomycin A (#19-148) were purchased from Sigma-Aldrich (St. Louis, MO, USA). Rabbit polyclonal against SARS S1 antibodies (#40150-T62), mouse monoclonal against MERS-CoV S2 antibody (#40070-MM11), mouse monoclonal against SARS S1 antibody (#40150-MM02), rabbit polyclonal against HIV-1 Gag-p24 antibody (11695-RP01) were purchased from Sino Biological Inc. (Beijing, China). Goat polyclonal against human ACE2 antibody (#AF933) was purchased from R\u0026D Systems (Minnesota, USA). Mouse monoclonal anti-FLAG M2 antibody was purchased from Sigma-Aldrich. Donkey Anti-Rabbit IgG (#711-035-152), Goat Anti-Mouse IgG (#115-035-146), and Rabbit Anti-Goat IgG (#305-035-003) were purchased from Jackson ImmunoResearch (West Grove, PA, USA). Alexa Fluor 488-conjugated goat anti-rabbit IgG, Alexa Fluor 488-conjugated goat anti-mouse IgG were purchased from ZSGB-Bio LLC (Beijing, China)."}