PMC:7100515 / 28644-29045 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T239","span":{"begin":121,"end":129},"obj":"Body_part"},{"id":"T240","span":{"begin":161,"end":166},"obj":"Body_part"},{"id":"T241","span":{"begin":168,"end":173},"obj":"Body_part"},{"id":"T242","span":{"begin":267,"end":272},"obj":"Body_part"}],"attributes":[{"id":"A239","pred":"fma_id","subj":"T239","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A240","pred":"fma_id","subj":"T240","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A241","pred":"fma_id","subj":"T241","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A242","pred":"fma_id","subj":"T242","obj":"http://purl.org/sig/ont/fma/fma63083"}],"text":"SARS-CoV and SARS-CoV-2 S pseudovirions were pre-incubated with serially diluted patient sera for 1 h on ice, then virus-antibody mixture was added on 293/hACE2 cells. Cells were lysed 40 h later and pseudovirus transduction was measured. The highest dilution of the serum sample that decreased transduction by 50% or more was considered to be positive. Source data are provided as a Source Data file."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T9","span":{"begin":267,"end":272},"obj":"Body_part"}],"attributes":[{"id":"A9","pred":"uberon_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/UBERON_0001977"}],"text":"SARS-CoV and SARS-CoV-2 S pseudovirions were pre-incubated with serially diluted patient sera for 1 h on ice, then virus-antibody mixture was added on 293/hACE2 cells. Cells were lysed 40 h later and pseudovirus transduction was measured. The highest dilution of the serum sample that decreased transduction by 50% or more was considered to be positive. Source data are provided as a Source Data file."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T279","span":{"begin":0,"end":8},"obj":"Disease"},{"id":"T280","span":{"begin":13,"end":21},"obj":"Disease"}],"attributes":[{"id":"A279","pred":"mondo_id","subj":"T279","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A280","pred":"mondo_id","subj":"T280","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"SARS-CoV and SARS-CoV-2 S pseudovirions were pre-incubated with serially diluted patient sera for 1 h on ice, then virus-antibody mixture was added on 293/hACE2 cells. Cells were lysed 40 h later and pseudovirus transduction was measured. The highest dilution of the serum sample that decreased transduction by 50% or more was considered to be positive. Source data are provided as a Source Data file."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T635","span":{"begin":115,"end":120},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T636","span":{"begin":151,"end":154},"obj":"http://purl.obolibrary.org/obo/CLO_0001230"},{"id":"T637","span":{"begin":151,"end":154},"obj":"http://purl.obolibrary.org/obo/CLO_0037237"},{"id":"T638","span":{"begin":151,"end":154},"obj":"http://purl.obolibrary.org/obo/CLO_0050903"},{"id":"T639","span":{"begin":151,"end":154},"obj":"http://purl.obolibrary.org/obo/CLO_0054249"},{"id":"T640","span":{"begin":151,"end":154},"obj":"http://purl.obolibrary.org/obo/CLO_0054250"},{"id":"T641","span":{"begin":151,"end":154},"obj":"http://purl.obolibrary.org/obo/CLO_0054251"},{"id":"T642","span":{"begin":151,"end":154},"obj":"http://purl.obolibrary.org/obo/CLO_0054252"},{"id":"T643","span":{"begin":161,"end":166},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T644","span":{"begin":168,"end":173},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T645","span":{"begin":382,"end":383},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"SARS-CoV and SARS-CoV-2 S pseudovirions were pre-incubated with serially diluted patient sera for 1 h on ice, then virus-antibody mixture was added on 293/hACE2 cells. Cells were lysed 40 h later and pseudovirus transduction was measured. The highest dilution of the serum sample that decreased transduction by 50% or more was considered to be positive. Source data are provided as a Source Data file."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T217","span":{"begin":130,"end":137},"obj":"Chemical"}],"attributes":[{"id":"A217","pred":"chebi_id","subj":"T217","obj":"http://purl.obolibrary.org/obo/CHEBI_60004"}],"text":"SARS-CoV and SARS-CoV-2 S pseudovirions were pre-incubated with serially diluted patient sera for 1 h on ice, then virus-antibody mixture was added on 293/hACE2 cells. Cells were lysed 40 h later and pseudovirus transduction was measured. The highest dilution of the serum sample that decreased transduction by 50% or more was considered to be positive. Source data are provided as a Source Data file."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T52","span":{"begin":212,"end":224},"obj":"http://purl.obolibrary.org/obo/GO_0009293"},{"id":"T53","span":{"begin":295,"end":307},"obj":"http://purl.obolibrary.org/obo/GO_0009293"}],"text":"SARS-CoV and SARS-CoV-2 S pseudovirions were pre-incubated with serially diluted patient sera for 1 h on ice, then virus-antibody mixture was added on 293/hACE2 cells. Cells were lysed 40 h later and pseudovirus transduction was measured. The highest dilution of the serum sample that decreased transduction by 50% or more was considered to be positive. Source data are provided as a Source Data file."}

{"project":"LitCovid-sentences","denotations":[{"id":"T212","span":{"begin":0,"end":167},"obj":"Sentence"},{"id":"T213","span":{"begin":168,"end":238},"obj":"Sentence"},{"id":"T214","span":{"begin":239,"end":353},"obj":"Sentence"},{"id":"T215","span":{"begin":354,"end":401},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"SARS-CoV and SARS-CoV-2 S pseudovirions were pre-incubated with serially diluted patient sera for 1 h on ice, then virus-antibody mixture was added on 293/hACE2 cells. Cells were lysed 40 h later and pseudovirus transduction was measured. The highest dilution of the serum sample that decreased transduction by 50% or more was considered to be positive. Source data are provided as a Source Data file."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1171","span":{"begin":155,"end":160},"obj":"Gene"},{"id":"1172","span":{"begin":24,"end":25},"obj":"Gene"},{"id":"1173","span":{"begin":0,"end":8},"obj":"Species"},{"id":"1174","span":{"begin":13,"end":23},"obj":"Species"},{"id":"1175","span":{"begin":81,"end":88},"obj":"Species"}],"attributes":[{"id":"A1171","pred":"tao:has_database_id","subj":"1171","obj":"Gene:59272"},{"id":"A1172","pred":"tao:has_database_id","subj":"1172","obj":"Gene:43740568"},{"id":"A1173","pred":"tao:has_database_id","subj":"1173","obj":"Tax:694009"},{"id":"A1174","pred":"tao:has_database_id","subj":"1174","obj":"Tax:2697049"},{"id":"A1175","pred":"tao:has_database_id","subj":"1175","obj":"Tax:9606"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"SARS-CoV and SARS-CoV-2 S pseudovirions were pre-incubated with serially diluted patient sera for 1 h on ice, then virus-antibody mixture was added on 293/hACE2 cells. Cells were lysed 40 h later and pseudovirus transduction was measured. The highest dilution of the serum sample that decreased transduction by 50% or more was considered to be positive. Source data are provided as a Source Data file."}