PMC:7100515 / 13652-15291
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T123 | 267-272 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T124 | 705-710 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T125 | 834-838 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T126 | 1081-1088 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T127 | 1157-1162 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T123 | 25-33 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T124 | 154-162 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T125 | 358-366 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T126 | 671-680 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T127 | 814-829 | Disease | denotes | Viral infection | http://purl.obolibrary.org/obo/MONDO_0005108 |
T128 | 820-829 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T129 | 883-886 | Disease | denotes | MTT | http://purl.obolibrary.org/obo/MONDO_0016757 |
T130 | 1068-1076 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T131 | 1260-1268 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T294 | 0-1 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T295 | 54-57 | http://purl.obolibrary.org/obo/CLO_0001230 | denotes | 293 |
T296 | 54-57 | http://purl.obolibrary.org/obo/CLO_0037237 | denotes | 293 |
T297 | 54-57 | http://purl.obolibrary.org/obo/CLO_0050903 | denotes | 293 |
T298 | 54-57 | http://purl.obolibrary.org/obo/CLO_0054249 | denotes | 293 |
T299 | 54-57 | http://purl.obolibrary.org/obo/CLO_0054250 | denotes | 293 |
T300 | 54-57 | http://purl.obolibrary.org/obo/CLO_0054251 | denotes | 293 |
T301 | 54-57 | http://purl.obolibrary.org/obo/CLO_0054252 | denotes | 293 |
T302 | 125-126 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T303 | 129-130 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | b |
T304 | 201-202 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T305 | 231-235 | http://purl.obolibrary.org/obo/CLO_0003684 | denotes | HeLa |
T306 | 231-235 | http://purl.obolibrary.org/obo/CLO_0050910 | denotes | HeLa |
T307 | 245-248 | http://purl.obolibrary.org/obo/CLO_0001230 | denotes | 293 |
T308 | 245-248 | http://purl.obolibrary.org/obo/CLO_0037237 | denotes | 293 |
T309 | 245-248 | http://purl.obolibrary.org/obo/CLO_0050903 | denotes | 293 |
T310 | 245-248 | http://purl.obolibrary.org/obo/CLO_0054249 | denotes | 293 |
T311 | 245-248 | http://purl.obolibrary.org/obo/CLO_0054250 | denotes | 293 |
T312 | 245-248 | http://purl.obolibrary.org/obo/CLO_0054251 | denotes | 293 |
T313 | 245-248 | http://purl.obolibrary.org/obo/CLO_0054252 | denotes | 293 |
T314 | 256-260 | http://purl.obolibrary.org/obo/CLO_0003684 | denotes | HeLa |
T315 | 256-260 | http://purl.obolibrary.org/obo/CLO_0050910 | denotes | HeLa |
T316 | 267-272 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T317 | 425-433 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
T318 | 504-505 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T319 | 703-710 | http://purl.obolibrary.org/obo/CLO_0001757 | denotes | 1 cells |
T320 | 834-838 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T321 | 1147-1150 | http://purl.obolibrary.org/obo/CLO_0001230 | denotes | 293 |
T322 | 1147-1150 | http://purl.obolibrary.org/obo/CLO_0037237 | denotes | 293 |
T323 | 1147-1150 | http://purl.obolibrary.org/obo/CLO_0050903 | denotes | 293 |
T324 | 1147-1150 | http://purl.obolibrary.org/obo/CLO_0054249 | denotes | 293 |
T325 | 1147-1150 | http://purl.obolibrary.org/obo/CLO_0054250 | denotes | 293 |
T326 | 1147-1150 | http://purl.obolibrary.org/obo/CLO_0054251 | denotes | 293 |
T327 | 1147-1150 | http://purl.obolibrary.org/obo/CLO_0054252 | denotes | 293 |
T328 | 1157-1162 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T329 | 1326-1334 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
T330 | 1620-1621 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T114 | 96-101 | Chemical | denotes | NH4Cl | http://purl.obolibrary.org/obo/CHEBI_31206 |
T115 | 211-220 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
T116 | 698-702 | Chemical | denotes | 17Cl | http://purl.obolibrary.org/obo/CHEBI_23116 |
T117 | 883-886 | Chemical | denotes | MTT | http://purl.obolibrary.org/obo/CHEBI_53233 |
T118 | 1081-1088 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T119 | 1305-1309 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
T120 | 1391-1400 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
T121 | 1420-1429 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T18 | 457-469 | http://purl.obolibrary.org/obo/GO_0009293 | denotes | transduction |
T19 | 814-829 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | Viral infection |
T20 | 1359-1371 | http://purl.obolibrary.org/obo/GO_0009293 | denotes | transduction |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T98 | 0-230 | Sentence | denotes | a Inhibition of entry of SARS-CoV-2 S pseudovirion on 293/hACE2 by lysosomotropic agents (20 mM NH4Cl and 100 nM bafilomycin A). b Inhibition of entry of SARS-CoV, MERS-CoV, and MHV S pseudovirions by a PIKfyve inhibitor apilimod. |
T99 | 231-409 | Sentence | denotes | HeLa/mCEACAM, 293/hACE2, HeLa/hDPP4 cells were pretreated with different concentrations of apilimod and transduced with MHV S, SARS-CoV S, MERS-CoV S pseudovirions, respectively. |
T100 | 410-470 | Sentence | denotes | The luciferase activity was measured 40 h post transduction. |
T101 | 471-514 | Sentence | denotes | VSV-G pseudovirions were used as a control. |
T102 | 515-586 | Sentence | denotes | Experiments were done in triplicates and repeated at least three times. |
T103 | 587-693 | Sentence | denotes | One representative is shown with error bars indicating SEM. c Inhibition of MHV A59 infection by apilimod. |
T104 | 694-813 | Sentence | denotes | The 17Cl.1 cells were pretreated with 3, 10, 30, 100, 300 nM apilimod for 30 min and infected by MHV A59 at MOI = 0.01. |
T105 | 814-907 | Sentence | denotes | Viral infection and cell viability were determined by using qPCR and MTT assay, respectively. |
T106 | 908-979 | Sentence | denotes | Experiments were done in triplicates and repeated at least three times. |
T107 | 980-1142 | Sentence | denotes | One representative is shown with error bars indicating SEM. d, e Inhibition of entry of SARS-CoV-2 S protein pseudovirions by apilimod, YM201636, and tetrandrine. |
T108 | 1143-1310 | Sentence | denotes | HEK 293/hACE2 cells were pretreated with either apilimod (d), YM201636 (e), or tetrandrine (f), then inoculated with SARS-CoV-2 S pseudovirons in the presence of drug. |
T109 | 1311-1372 | Sentence | denotes | The luciferase activity were measured 40 h post transduction. |
T110 | 1373-1430 | Sentence | denotes | YM201636, PIKfyve inhibitor; tetrandrine, TPC2 inhibitor. |
T111 | 1431-1506 | Sentence | denotes | The experiments were done in triplicates and repeated at least three times. |
T112 | 1507-1591 | Sentence | denotes | One representative is shown with error bars indicating SEM of technical triplicates. |
T113 | 1592-1639 | Sentence | denotes | Source data are provided as a Source Data file. |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
593 | 58-63 | Gene | denotes | hACE2 | Gene:59272 |
594 | 249-254 | Gene | denotes | hACE2 | Gene:59272 |
595 | 1151-1156 | Gene | denotes | hACE2 | Gene:59272 |
596 | 1415-1419 | Gene | denotes | TPC2 | Gene:219931 |
597 | 261-266 | Gene | denotes | hDPP4 | Gene:1803 |
598 | 1271-1272 | Gene | denotes | S | Gene:43740568 |
599 | 1079-1080 | Gene | denotes | S | Gene:43740568 |
600 | 36-37 | Gene | denotes | S | Gene:43740568 |
601 | 25-35 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
602 | 154-162 | Species | denotes | SARS-CoV | Tax:694009 |
603 | 164-172 | Species | denotes | MERS-CoV | Tax:1335626 |
604 | 178-183 | Species | denotes | MHV S | Tax:11145 |
605 | 351-356 | Species | denotes | MHV S | Tax:11145 |
606 | 358-366 | Species | denotes | SARS-CoV | Tax:694009 |
607 | 370-378 | Species | denotes | MERS-CoV | Tax:1335626 |
608 | 1068-1078 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
609 | 1260-1270 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
610 | 663-666 | Species | denotes | MHV | Tax:11138 |
611 | 791-794 | Species | denotes | MHV | Tax:11138 |
612 | 96-101 | Chemical | denotes | NH4Cl | |
613 | 113-126 | Chemical | denotes | bafilomycin A | MESH:C057620 |
614 | 883-886 | Chemical | denotes | MTT | MESH:C070243 |
615 | 1106-1114 | Chemical | denotes | apilimod | MESH:C504227 |
616 | 1116-1124 | Chemical | denotes | YM201636 | MESH:C540576 |
617 | 1130-1141 | Chemical | denotes | tetrandrine | MESH:C009438 |
618 | 1205-1213 | Chemical | denotes | YM201636 | MESH:C540576 |
619 | 1222-1233 | Chemical | denotes | tetrandrine | MESH:C009438 |
620 | 1373-1381 | Chemical | denotes | YM201636 | MESH:C540576 |
621 | 1402-1413 | Chemical | denotes | tetrandrine | MESH:C009438 |
622 | 671-680 | Disease | denotes | infection | MESH:D007239 |
623 | 779-787 | Disease | denotes | infected | MESH:D007239 |
624 | 814-829 | Disease | denotes | Viral infection | MESH:D001102 |
625 | 231-235 | CellLine | denotes | HeLa | CVCL:0030 |
626 | 256-260 | CellLine | denotes | HeLa | CVCL:0030 |
627 | 1143-1150 | CellLine | denotes | HEK 293 | CVCL:0045 |