PMC:7100515 / 124-1071
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T2 | 256-263 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T3 | 416-421 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T4 | 532-539 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T3 | 75-83 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T4 | 138-146 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T5 | 219-227 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T6 | 243-251 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T7 | 366-374 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T8 | 388-396 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T9 | 519-527 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T10 | 560-568 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T11 | 588-592 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T12 | 628-636 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T13 | 647-655 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T14 | 707-711 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T15 | 716-724 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T16 | 809-818 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T17 | 936-944 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2 | 300-305 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T3 | 406-409 | http://purl.obolibrary.org/obo/CLO_0001230 | denotes | 293 |
| T4 | 406-409 | http://purl.obolibrary.org/obo/CLO_0037237 | denotes | 293 |
| T5 | 406-409 | http://purl.obolibrary.org/obo/CLO_0050903 | denotes | 293 |
| T6 | 406-409 | http://purl.obolibrary.org/obo/CLO_0054249 | denotes | 293 |
| T7 | 406-409 | http://purl.obolibrary.org/obo/CLO_0054250 | denotes | 293 |
| T8 | 406-409 | http://purl.obolibrary.org/obo/CLO_0054251 | denotes | 293 |
| T9 | 406-409 | http://purl.obolibrary.org/obo/CLO_0054252 | denotes | 293 |
| T10 | 416-421 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T11 | 593-595 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T2 | 12-16 | Chemical | denotes | beta | http://purl.obolibrary.org/obo/CHEBI_10545 |
| T3 | 256-263 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T4 | 306-317 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
| T5 | 532-539 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T6 | 913-918 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 437-448 | http://purl.obolibrary.org/obo/GO_0006897 | denotes | endocytosis |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3 | 0-162 | Sentence | denotes | Since 2002, beta coronaviruses (CoV) have caused three zoonotic outbreaks, SARS-CoV in 2002–2003, MERS-CoV in 2012, and the newly emerged SARS-CoV-2 in late 2019. |
| T4 | 163-230 | Sentence | denotes | However, little is currently known about the biology of SARS-CoV-2. |
| T5 | 231-571 | Sentence | denotes | Here, using SARS-CoV-2 S protein pseudovirus system, we confirm that human angiotensin converting enzyme 2 (hACE2) is the receptor for SARS-CoV-2, find that SARS-CoV-2 enters 293/hACE2 cells mainly through endocytosis, that PIKfyve, TPC2, and cathepsin L are critical for entry, and that SARS-CoV-2 S protein is less stable than SARS-CoV S. |
| T6 | 572-674 | Sentence | denotes | Polyclonal anti-SARS S1 antibodies T62 inhibit entry of SARS-CoV S but not SARS-CoV-2 S pseudovirions. |
| T7 | 675-855 | Sentence | denotes | Further studies using recovered SARS and COVID-19 patients’ sera show limited cross-neutralization, suggesting that recovery from one infection might not protect against the other. |
| T8 | 856-947 | Sentence | denotes | Our results present potential targets for development of drugs and vaccines for SARS-CoV-2. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 29 | 306-337 | Gene | denotes | angiotensin converting enzyme 2 | Gene:59272 |
| 30 | 339-344 | Gene | denotes | hACE2 | Gene:59272 |
| 31 | 410-415 | Gene | denotes | hACE2 | Gene:59272 |
| 32 | 464-468 | Gene | denotes | TPC2 | Gene:219931 |
| 33 | 474-485 | Gene | denotes | cathepsin L | Gene:1514 |
| 34 | 658-659 | Gene | denotes | S | Gene:43740568 |
| 35 | 530-531 | Gene | denotes | S | Gene:43740568 |
| 36 | 254-255 | Gene | denotes | S | Gene:43740568 |
| 37 | 12-30 | Species | denotes | beta coronaviruses | Tax:694002 |
| 38 | 32-35 | Species | denotes | CoV | Tax:11118 |
| 39 | 75-83 | Species | denotes | SARS-CoV | Tax:694009 |
| 40 | 98-106 | Species | denotes | MERS-CoV | Tax:1335626 |
| 41 | 138-148 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 42 | 219-229 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 43 | 243-253 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 44 | 300-305 | Species | denotes | human | Tax:9606 |
| 45 | 366-376 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 46 | 388-398 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 47 | 519-529 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 48 | 628-636 | Species | denotes | SARS-CoV | Tax:694009 |
| 49 | 647-657 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 50 | 725-733 | Species | denotes | patients | Tax:9606 |
| 51 | 936-946 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 52 | 560-568 | Species | denotes | SARS-CoV | Tax:694009 |
| 53 | 55-63 | Disease | denotes | zoonotic | MESH:D015047 |
| 54 | 716-724 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 55 | 809-818 | Disease | denotes | infection | MESH:D007239 |