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PMC:7095437 / 20384-29129 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
371 24-32 Species denotes patients Tax:9606
372 280-287 Species denotes patient Tax:9606
373 583-591 Species denotes patients Tax:9606
374 754-762 Species denotes patients Tax:9606
375 977-985 Species denotes patients Tax:9606
376 38-46 Disease denotes COVID-19 MESH:C000657245
377 406-414 Disease denotes COVID-19 MESH:C000657245
378 716-724 Disease denotes COVID-19 MESH:C000657245
379 768-776 Disease denotes COVID-19 MESH:C000657245
380 838-873 Disease denotes pulmonary parenchymal abnormalities MESH:D008171
381 1077-1092 Disease denotes viral infection MESH:D001102
400 1665-1673 Species denotes patients Tax:9606
401 1750-1758 Species denotes patients Tax:9606
402 1820-1830 Species denotes SARS-CoV-2 Tax:2697049
403 1935-1948 Species denotes coronaviruses Tax:11118
404 1987-1995 Species denotes SARS-CoV Tax:694009
405 2032-2040 Species denotes MERS-CoV Tax:1335626
406 2151-2164 Species denotes coronaviruses Tax:11118
407 2233-2241 Species denotes patients Tax:9606
408 2289-2297 Species denotes patients Tax:9606
409 1311-1319 Disease denotes COVID-19 MESH:C000657245
410 1483-1501 Disease denotes pulmonary fibrosis MESH:D011658
411 1513-1530 Disease denotes pleural effusions MESH:D010996
412 1679-1687 Disease denotes COVID-19 MESH:C000657245
413 1741-1749 Disease denotes COVID-19 MESH:C000657245
414 1896-1922 Disease denotes acute respiratory syndrome MESH:D012120
415 2079-2095 Disease denotes viral infections MESH:D001102
416 2224-2232 Disease denotes COVID-19 MESH:C000657245
417 2474-2481 Disease denotes thrombi MESH:D013927
435 2926-2934 Species denotes patients Tax:9606
436 3290-3298 Species denotes MERS-CoV Tax:1335626
437 3527-3535 Species denotes patients Tax:9606
438 3567-3580 Species denotes coronaviruses Tax:11118
439 3810-3820 Species denotes SARS-CoV-2 Tax:2697049
440 3846-3854 Species denotes SARS-CoV Tax:694009
441 4033-4041 Species denotes patients Tax:9606
442 2771-2779 Disease denotes COVID-19 MESH:C000657245
443 3132-3143 Disease denotes hyperplasia MESH:D006965
444 3251-3259 Disease denotes COVID-19 MESH:C000657245
445 3270-3279 Disease denotes pneumonia MESH:D011014
446 3437-3453 Disease denotes pleural effusion MESH:D010996
447 3517-3526 Disease denotes pneumonia MESH:D011014
448 3536-3544 Disease denotes infected MESH:D007239
449 3626-3634 Disease denotes COVID-19 MESH:C000657245
450 3939-3947 Disease denotes COVID-19 MESH:C000657245
451 4070-4079 Disease denotes infection MESH:D007239
459 4497-4505 Species denotes patients Tax:9606
460 4565-4572 Species denotes patient Tax:9606
461 4160-4168 Disease denotes COVID-19 MESH:C000657245
462 4488-4496 Disease denotes COVID-19 MESH:C000657245
463 4588-4596 Disease denotes COVID-19 MESH:C000657245
464 4808-4816 Disease denotes COVID-19 MESH:C000657245
465 4864-4872 Disease denotes COVID-19 MESH:C000657245
474 5754-5762 Species denotes SARS-CoV Tax:694009
475 4986-4994 Disease denotes COVID-19 MESH:C000657245
476 5086-5094 Disease denotes COVID-19 MESH:C000657245
477 5196-5204 Disease denotes COVID-19 MESH:C000657245
478 5734-5743 Disease denotes pneumonia MESH:D011014
479 5835-5853 Disease denotes SARS-CoV infection MESH:C000657245
480 6002-6010 Disease denotes COVID-19 MESH:C000657245
481 6088-6096 Disease denotes COVID-19 MESH:C000657245
489 7070-7078 Species denotes patients Tax:9606
490 7249-7257 Species denotes patients Tax:9606
491 7316-7324 Species denotes patients Tax:9606
492 6465-6477 Disease denotes inflammation MESH:D007249
493 6589-6597 Disease denotes COVID-19 MESH:C000657245
494 6958-6966 Disease denotes COVID-19 MESH:C000657245
495 7185-7196 Disease denotes lung injury MESH:D055370
500 8149-8157 Species denotes patients Tax:9606
501 7376-7384 Disease denotes COVID-19 MESH:C000657245
502 7390-7403 Disease denotes novel disease MESH:C000657245
503 8003-8012 Disease denotes infection MESH:D007239
514 8609-8617 Species denotes patients Tax:9606
515 8722-8730 Species denotes patients Tax:9606
516 8249-8284 Disease denotes pulmonary parenchymal abnormalities MESH:D008171
517 8310-8318 Disease denotes COVID-19 MESH:C000657245
518 8414-8422 Disease denotes COVID-19 MESH:C000657245
519 8488-8496 Disease denotes COVID-19 MESH:C000657245
520 8571-8579 Disease denotes COVID-19 MESH:C000657245
521 8623-8630 Disease denotes dyspnea MESH:D004417
522 8635-8655 Disease denotes respiratory distress MESH:D012128
523 8736-8744 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T84 147-152 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T85 787-792 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T86 953-958 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T87 1101-1114 Body_part denotes immune system http://purl.org/sig/ont/fma/fma9825
T88 1551-1556 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T89 1656-1661 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T90 1726-1730 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T91 1731-1737 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T92 2348-2364 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T93 2359-2364 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T94 2452-2458 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T95 2459-2464 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T96 2506-2520 Body_part denotes fibrous tissue http://purl.org/sig/ont/fma/fma63898
T97 2866-2870 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T98 3044-3048 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T99 3326-3331 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T100 3399-3403 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T101 4292-4296 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T102 4469-4474 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T103 4533-4538 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T104 4663-4668 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T105 4777-4781 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T106 5490-5509 Body_part denotes alveolar epithelium http://purl.org/sig/ont/fma/fma63915
T107 5499-5509 Body_part denotes epithelium http://purl.org/sig/ont/fma/fma9639
T108 5616-5620 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T109 5621-5627 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T110 7185-7189 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T111 7542-7547 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T112 8196-8201 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T113 8372-8376 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T67 147-152 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T68 787-792 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T69 953-958 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T70 1101-1114 Body_part denotes immune system http://purl.obolibrary.org/obo/UBERON_0002405
T71 1513-1530 Body_part denotes pleural effusions http://purl.obolibrary.org/obo/UBERON_0000175
T72 1551-1556 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T73 1726-1730 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T74 1731-1737 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T75 2452-2458 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T76 2514-2520 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T77 2866-2870 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T78 3044-3048 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T79 3326-3331 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T80 3399-3403 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T81 3437-3453 Body_part denotes pleural effusion http://purl.obolibrary.org/obo/UBERON_0000175
T82 4292-4296 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T83 4469-4474 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T84 4533-4538 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T85 4777-4781 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T86 5499-5509 Body_part denotes epithelium http://purl.obolibrary.org/obo/UBERON_0000483
T87 5616-5620 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T88 5621-5627 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T89 7185-7189 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T90 7542-7547 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T91 8196-8201 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T92 8372-8376 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T83 38-46 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T84 406-414 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T85 716-724 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T86 768-776 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T87 1077-1092 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T88 1083-1092 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T89 1311-1319 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T90 1483-1501 Disease denotes pulmonary fibrosis http://purl.obolibrary.org/obo/MONDO_0002771
T91 1679-1687 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T92 1741-1749 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T93 1820-1828 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T94 1820-1824 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T95 1889-1922 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T96 1924-1928 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T97 1987-1995 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T98 1987-1991 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T99 2079-2098 Disease denotes viral infections in http://purl.obolibrary.org/obo/MONDO_0005108
T100 2224-2232 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T101 2284-2288 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T102 2328-2334 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T103 2771-2779 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T104 2921-2925 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T105 3132-3143 Disease denotes hyperplasia http://purl.obolibrary.org/obo/MONDO_0005043
T106 3251-3259 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T107 3270-3279 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T108 3517-3526 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T109 3626-3634 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T110 3765-3769 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T111 3810-3818 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T112 3810-3814 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T113 3846-3854 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T114 3846-3850 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T115 3939-3947 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T116 4070-4079 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T117 4160-4168 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T118 4488-4496 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T119 4588-4596 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T120 4808-4816 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T121 4864-4872 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T122 4986-4994 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T123 5086-5094 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T124 5196-5204 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T125 5734-5743 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T126 5754-5762 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T127 5754-5758 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T128 5835-5853 Disease denotes SARS-CoV infection http://purl.obolibrary.org/obo/MONDO_0005091
T129 5835-5839 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T130 5844-5853 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T131 6002-6010 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T132 6088-6096 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T133 6465-6477 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T134 6589-6597 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T135 6958-6966 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T136 7115-7119 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T137 7190-7196 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T138 7219-7223 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T139 7376-7384 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T140 8003-8012 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T141 8310-8318 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T142 8414-8422 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T143 8488-8496 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T144 8571-8579 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T145 8736-8744 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T160 125-127 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T161 147-152 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T162 271-273 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T163 329-332 http://purl.obolibrary.org/obo/CLO_0001000 denotes 3–5
T164 493-496 http://purl.obolibrary.org/obo/CLO_0001000 denotes 3–5
T165 787-792 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T166 953-958 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T167 1101-1114 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T168 1406-1407 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T169 1513-1530 http://purl.obolibrary.org/obo/UBERON_0000175 denotes pleural effusions
T170 1551-1556 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T171 1656-1661 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T172 1726-1730 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T173 1726-1730 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T174 1877-1880 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T175 2046-2048 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T176 2348-2358 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T177 2359-2364 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T178 2374-2382 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T179 2434-2435 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T180 2459-2464 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T181 2542-2548 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T182 2557-2563 http://purl.obolibrary.org/obo/UBERON_0002553 denotes cavity
T183 2866-2870 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T184 2866-2870 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T185 3044-3048 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T186 3044-3048 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T187 3326-3331 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T188 3399-3403 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T189 3399-3403 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T190 3417-3419 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T191 3437-3453 http://purl.obolibrary.org/obo/UBERON_0000175 denotes pleural effusion
T192 4292-4296 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T193 4292-4296 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T194 4469-4474 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T195 4533-4538 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T196 4551-4552 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T197 4663-4668 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T198 4777-4781 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T199 4777-4781 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T200 4786-4787 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T201 5499-5509 http://purl.obolibrary.org/obo/UBERON_0000483 denotes epithelium
T202 5524-5529 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T203 5616-5620 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T204 5616-5620 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T205 5642-5643 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T206 7015-7016 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T207 7095-7096 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T208 7160-7161 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T209 7185-7189 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T210 7185-7189 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T211 7294-7302 http://purl.obolibrary.org/obo/CLO_0001658 denotes actively
T212 7388-7389 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T213 7414-7415 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T214 7494-7495 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T215 7542-7547 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T216 7962-7967 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T217 8025-8030 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T218 8196-8201 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T219 8372-8376 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T220 8372-8376 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T221 8445-8446 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T222 8504-8505 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T40 1011-1020 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T41 6174-6179 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T42 6237-6242 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T43 6568-6577 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T44 6739-6748 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T29 1483-1501 Phenotype denotes pulmonary fibrosis http://purl.obolibrary.org/obo/HP_0002206
T30 1513-1530 Phenotype denotes pleural effusions http://purl.obolibrary.org/obo/HP_0002202
T31 3270-3279 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T32 3437-3453 Phenotype denotes pleural effusion http://purl.obolibrary.org/obo/HP_0002202
T33 3470-3489 Phenotype denotes tree-in-bud pattern http://purl.obolibrary.org/obo/HP_0032174
T34 3517-3526 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T35 5734-5743 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T36 8623-8630 Phenotype denotes dyspnea http://purl.obolibrary.org/obo/HP_0002094
T37 8635-8655 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T5 1077-1092 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T6 2063-2075 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis
T7 2079-2095 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T8 2383-2392 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T9 5451-5460 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T10 6465-6477 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation

0_colil

Id Subject Object Predicate Lexical cue
32211963-31986261-62969 267-269 31986261 denotes 10
32211963-32007145-62970 2046-2048 32007145 denotes 18
32211963-29757717-62971 2565-2567 29757717 denotes 19
32211963-12738877-62972 3261-3263 12738877 denotes 20
32211963-25615627-62973 3413-3415 25615627 denotes 21
32211963-24918624-62974 3417-3419 24918624 denotes 22
32211963-31978293-62975 3856-3858 31978293 denotes 23
32211963-31986264-62976 4507-4508 31986264 denotes 7
32211963-14990845-62977 5961-5963 14990845 denotes 15
32211963-12853655-62978 7225-7227 12853655 denotes 24

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T176 0-10 Sentence denotes Discussion
T177 11-129 Sentence denotes As reported, patients with COVID-19 usually develop clinical symptoms after an incubation period of 4.1–7.0 days [11].
T178 130-195 Sentence denotes After admission, chest imaging examination was performed on them.
T179 196-564 Sentence denotes According to the results of changes in this disease in recent studies [10, 11], the patient’s condition progressively worsens on the 3–5 days after symptom onset, and the guidelines for an imaging diagnosis of COVID-19 recommend that reviewing CT or plain radiograph is needed for suspected cases 3–5 days after diagnosis to observe changes in the disease status [12].
T180 565-725 Sentence denotes Thus, we assigned patients to two groups according to the time of onset of symptoms to analyze the CT findings in early-stage and progressive-stage of COVID-19.
T181 726-883 Sentence denotes In this study, 62 confirmed patients with COVID-19 underwent chest CT scans, and positive rate of detecting the pulmonary parenchymal abnormalities was 100%.
T182 884-1268 Sentence denotes In addition, the CT data in our study were obtained from the initial chest CT examination of patients who had not received any antiviral therapy; these results may better reflect the degree of viral infection and the immune system status before clinical intervention and provide an important basis for clinical classification, treatment strategy development, and prognosis prediction.
T183 1269-1469 Sentence denotes In our study, the major characteristic of COVID-19 was GGO (61.3%), followed by GGO with consolidation (35.5%), rounded opacity (25.8%), a crazy-paving pattern (25.8%), and an air bronchogram (22.6%).
T184 1470-1567 Sentence denotes In contrast, pulmonary fibrosis (1.6%) and pleural effusions (3.2%) were rare on chest CT images.
T185 1568-1688 Sentence denotes These various CT findings are likely related to the complex pathological changes in the lungs of patients with COVID-19.
T186 1689-2050 Sentence denotes Although pathological changes in the lung tissue of COVID-19 patients have not yet been studied, recent studies have reported that SARS-CoV-2 is closely related (with 88% identity) to two bat-derived severe acute respiratory syndrome (SARS)–like coronaviruses, with approximately 79% homology with SARS-CoV and approximately 50% homology with MERS-CoV [17, 18].
T187 2051-2280 Sentence denotes Because the pathogenesis of viral infections in the same family may be similar, previous studies on coronaviruses may be helpful in understanding the various CT findings in COVID-19 patients based on similar pathological changes.
T188 2281-2569 Sentence denotes In SARS patients, pathological changes include injury to pulmonary epithelial cells, hyaline membrane formation on in the inner wall of the alveoli, and a large number of tissue cells and mass thrombi formed by proliferative fibrous tissue that block the small airway and air cavity [19].
T189 2570-2671 Sentence denotes These pathological changes may be the main pathological basis of the CT findings, especially the GGO.
T190 2672-2879 Sentence denotes Among all the CT findings, GGO was the most common one in both the early and progressive stages of COVID-19 and was characterized by multiple sized lesions, mainly distributed in the peripheral lung (96.8%).
T191 2880-3190 Sentence denotes An analysis of thin-section CT images of SARS patients showed that multiple GGOs were the main imaging finding (68.4%) and were distributed in the periphery of the lung (71.8%), with interlobular septal thickening (24.2%) and intralobular interstitial hyperplasia (32.2%), also called the crazy-paving pattern.
T192 3191-3265 Sentence denotes These findings are very similar to the CT manifestations of COVID-19 [20].
T193 3266-3421 Sentence denotes For pneumonia caused by MERS-CoV, GGO was also found on the chest CT images and was mainly distributed in the subpleural and basilar lung regions [21, 22].
T194 3422-3581 Sentence denotes Interestingly, pleural effusion was rare and no tree-in-bud pattern or cavitation was found in pneumonia patients infected by the three kinds of coronaviruses.
T195 3582-3681 Sentence denotes In addition, we found that only one case of COVID-19 (1.6%) presented as consolidation without GGO.
T196 3682-3860 Sentence denotes Compared with the large amount of consolidation that appears in the early stage of SARS, we speculate that the pathogenicity of SARS-CoV-2 may be less than that of SARS-CoV [23].
T197 3861-4100 Sentence denotes Thus, it is necessary to fully understand and discriminate the CT features of COVID-19 at an early stage, which is helpful for the timely isolation and respiratory care of patients and early implementation of infection prevention measures.
T198 4101-4297 Sentence denotes In addition to GGO, another important CT characteristic of COVID-19 was multiple GGOs with consolidations, accompanied by interlobular septal thickening, mainly in the peripheral part of the lung.
T199 4298-4510 Sentence denotes These basic CT features were similar to the findings reported by Huang et al, whose study showed that multiple GGOs with partial consolidation appeared bilaterally on the chest CT images of COVID-19 patients [7].
T200 4511-4684 Sentence denotes Similarly, in another chest CT study of a 33-year-old patient diagnosed with COVID-19 in Wuhan, China, multiple GGOs distributed in both the peripheral lungs were found [5].
T201 4685-4873 Sentence denotes Therefore, we suggest that multiple GGOs with consolidations mainly in the periphery of the lung are a basic CT feature of COVID-19, which is helpful for the initial screening of COVID-19.
T202 4874-5021 Sentence denotes Unexpectedly, the halo sign (20.6%) was the only significantly different CT manifestation in the early stage of COVID-19 among all the CT findings.
T203 5022-5095 Sentence denotes In our study, the halo sign appeared in only the early stage of COVID-19.
T204 5096-5267 Sentence denotes We hypothesized that the halo sign rapidly changed into GGO within 1 week due to the aggravation of COVID-19, and no other new halo sign had been formed in the short term.
T205 5268-5394 Sentence denotes In addition, there were no significant differences in the other CT findings or distribution of lesions between the two stages.
T206 5395-5730 Sentence denotes For these findings, we speculated that the speed of GGO formation was due to the damage to the alveolar epithelium caused by the virus and may be similar to that of consolidation caused by an inflammatory reaction of the lung tissue, resulting in a change in different types of lesions during the synchronous increase in opacification.
T207 5731-5965 Sentence denotes In pneumonia caused by SARS-CoV, Ooi et al found that GGO and consolidation formed in the first week of SARS-CoV infection increased in the second week, and only residual strips and reticular shadows were seen in the fourth week [15].
T208 5966-6097 Sentence denotes Therefore, the CT manifestations of COVID-19 are different at different stages, which helps the differential diagnosis of COVID-19.
T209 6098-6243 Sentence denotes Furthermore, our results showed that the CT scores in the progressive-stage group were significantly greater than those in the early-stage group.
T210 6244-6524 Sentence denotes Further analysis showed that the CT scores were positively correlated with the maximum diameters of the lesions (r = 0.531), indicating that the range of lesions in the progressive stage was larger than and the degree of inflammation was more serious than that in the early stage.
T211 6525-6688 Sentence denotes These results also showed that without any antiviral treatment, COVID-19 continued to progress 5–7 days after the onset of symptoms, without any improvement trend.
T212 6689-6831 Sentence denotes Therefore, necessary clinical measures, including antiviral and supportive therapies, should be administered to prevent disease deterioration.
T213 6832-6987 Sentence denotes Because of the lack of additional data, the correlation between the CT score and clinical classification and the prognosis of COVID-19 needs further study.
T214 6988-7091 Sentence denotes Moreover, CT scores showed a significant positive correlation with ages in all 62 patients (r = 0.255).
T215 7092-7229 Sentence denotes In a previous study on SARS, Grinblat et al considered that age was a risk factor for severe lung injury and poor prognosis of SARS [24].
T216 7230-7325 Sentence denotes Therefore, elderly patients need to be treated earlier and more actively than younger patients.
T217 7326-7360 Sentence denotes Our study had several limitations.
T218 7361-7519 Sentence denotes First, because COVID-19 is a novel disease and lacks a series and long-term CT data, we can analyze only the existing information in a retrospective analysis.
T219 7520-7704 Sentence denotes Moreover, the time of chest CT examination after symptom onset was inconsistent, so it was difficult to summarize the CT appearances that could reflect the whole course of the disease.
T220 7705-7839 Sentence denotes Second, the sample size in our study was relatively small, and there may be deviation in the comparison of the results of CT findings.
T221 7840-7915 Sentence denotes Third, most of our cases were imported cases and some were secondary cases.
T222 7916-8085 Sentence denotes Further research is needed to observe whether virus variation exists in the process of infection and whether virus variation will produce different in CT manifestations.
T223 8086-8158 Sentence denotes Finally, there was no histopathological evidence from deceased patients.
T224 8159-8319 Sentence denotes In conclusion, our study showed that chest CT examination was very effective in detecting pulmonary parenchymal abnormalities in the natural course of COVID-19.
T225 8320-8423 Sentence denotes Multiple GGOs with consolidations in the peripheral lung was the primary CT characteristic of COVID-19.
T226 8424-8605 Sentence denotes The halo sign may be a special CT feature in the early stage of COVID-19, while a significantly increased CT score may indicate the aggravation of COVID-19 in the progressive stage.
T227 8606-8745 Sentence denotes In patients with dyspnea and respiratory distress, CT examination is very effective in the preclinical screening of patients with COVID-19.

TEST0

Id Subject Object Predicate Lexical cue
32211963-137-143-62969 267-269 ["31986261"] denotes 10
32211963-231-237-62970 2046-2048 ["32007145"] denotes 18
32211963-237-243-62971 2565-2567 ["29757717"] denotes 19
32211963-70-76-62972 3261-3263 ["12738877"] denotes 20
32211963-147-153-62973 3413-3415 ["25615627"] denotes 21
32211963-151-157-62974 3417-3419 ["24918624"] denotes 22
32211963-174-180-62975 3856-3858 ["31978293"] denotes 23
32211963-209-214-62976 4507-4508 ["31986264"] denotes 7
32211963-230-236-62977 5961-5963 ["14990845"] denotes 15
32211963-133-139-62978 7225-7227 ["12853655"] denotes 24

2_test

Id Subject Object Predicate Lexical cue
32211963-31986261-29369860 267-269 31986261 denotes 10
32211963-32007145-29369861 2046-2048 32007145 denotes 18
32211963-29757717-29369862 2565-2567 29757717 denotes 19
32211963-12738877-29369863 3261-3263 12738877 denotes 20
32211963-25615627-29369864 3413-3415 25615627 denotes 21
32211963-24918624-29369865 3417-3419 24918624 denotes 22
32211963-31978293-29369866 3856-3858 31978293 denotes 23
32211963-31986264-29369867 4507-4508 31986264 denotes 7
32211963-14990845-29369868 5961-5963 14990845 denotes 15
32211963-12853655-29369869 7225-7227 12853655 denotes 24

MyTest

Id Subject Object Predicate Lexical cue
32211963-31986261-29369860 267-269 31986261 denotes 10
32211963-32007145-29369861 2046-2048 32007145 denotes 18
32211963-29757717-29369862 2565-2567 29757717 denotes 19
32211963-12738877-29369863 3261-3263 12738877 denotes 20
32211963-25615627-29369864 3413-3415 25615627 denotes 21
32211963-24918624-29369865 3417-3419 24918624 denotes 22
32211963-31978293-29369866 3856-3858 31978293 denotes 23
32211963-31986264-29369867 4507-4508 31986264 denotes 7
32211963-14990845-29369868 5961-5963 14990845 denotes 15
32211963-12853655-29369869 7225-7227 12853655 denotes 24