PMC:7094172 / 8571-10117
Annnotations
LitCovid-PMC-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T669 | 36-44 | SP_9 | denotes | MERS-CoV |
T668 | 81-89 | SP_9 | denotes | MERS-CoV |
T667 | 220-232 | GO:0046983 | denotes | dimerization |
T666 | 300-308 | SP_9 | denotes | MERS-CoV |
T665 | 317-329 | GO:0051260 | denotes | Dimerization |
T664 | 352-358 | SO:0000440 | denotes | vector |
T663 | 885-891 | SO:0000440 | denotes | vector |
T662 | 1166-1172 | SO:0000440 | denotes | vector |
T661 | 1440-1458 | SO:0000366 | denotes | substitution sites |
T660 | 1500-1512 | GO:0046983 | denotes | dimerization |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T42 | 978-985 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T43 | 1327-1335 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T37 | 47-50 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
T39 | 92-95 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T60 | 53-54 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T61 | 145-146 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T62 | 273-279 | http://purl.obolibrary.org/obo/CLO_0001869 | denotes | B). (B |
T63 | 560-567 | http://purl.obolibrary.org/obo/CLO_0007225 | denotes | labeled |
T64 | 774-775 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T65 | 1205-1212 | http://purl.obolibrary.org/obo/CLO_0007225 | denotes | labeled |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T74 | 978-985 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T75 | 1327-1335 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T59 | 0-198 | Sentence | denotes | Figure 1 Structure and sequence of MERS-CoV N-NTD. (A) Overall structure of the MERS-CoV N-NTD dimer containing monomers 1 and 2 is depicted as a cartoon and colored yellow and green, respectively. |
T60 | 199-316 | Sentence | denotes | Residues involved in dimerization are shown as sticks and highlighted in (B). (B) Interactions among MERS-CoV N-NTDs. |
T61 | 317-514 | Sentence | denotes | Dimerization is mediated mainly by vector-fusion residues interacting with the conserved hydrophobic regions on the core structure (first area) along with the residues surrounding it (second area). |
T62 | 515-600 | Sentence | denotes | Interacting residues on monomers 1 and 2 are labeled in black and blue, respectively. |
T63 | 601-688 | Sentence | denotes | Vector-fusion and conserved hydrophobic regions are colored cyan and red, respectively. |
T64 | 689-777 | Sentence | denotes | The color of all other interacting residues is the same as that for each monomer in (A). |
T65 | 778-908 | Sentence | denotes | Polar contacts are indicated with red dashed lines. (C) Upper panel: close-up of the interacting region of vector-fusion residues. |
T66 | 909-994 | Sentence | denotes | The surface was colored according to the hydrophobicity level at the protein surface. |
T67 | 995-1082 | Sentence | denotes | Vector-fusion residues (black) are shown as sticks to emphasize the hydrophobic pocket. |
T68 | 1083-1095 | Sentence | denotes | Lower panel: |
T69 | 1096-1189 | Sentence | denotes | 2D diagrams of the interaction between the hydrophobic pocket and the vector-fusion residues. |
T70 | 1190-1222 | Sentence | denotes | The latter are labeled in black. |
T71 | 1223-1361 | Sentence | denotes | The hydrophobic contacts are indicated with black dashed lines. (D) Sequence alignment of various CoV N proteins in the N-terminal region. |
T72 | 1362-1411 | Sentence | denotes | Red letters indicate strictly conserved residues. |
T73 | 1412-1459 | Sentence | denotes | Cyan indicates conservative substitution sites. |
T74 | 1460-1546 | Sentence | denotes | Hydrophobic regions involved in unusual dimerization are indicated by black triangles. |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
131 | 113-129 | Gene | denotes | monomers 1 and 2 | |
132 | 539-555 | Gene | denotes | monomers 1 and 2 | |
133 | 36-44 | Species | denotes | MERS-CoV | Tax:1335626 |
134 | 81-89 | Species | denotes | MERS-CoV | Tax:1335626 |
135 | 1321-1324 | Species | denotes | CoV | Tax:11118 |
136 | 90-95 | Chemical | denotes | N-NTD | |
137 | 305-315 | Disease | denotes | CoV N-NTDs | MESH:C000657245 |