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PMC:7094172 / 38546-39336 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T175 279-286 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T176 302-305 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T124 147-150 Disease denotes NTD http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075
T126 199-202 Disease denotes NTD http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075
T128 483-492 Disease denotes hepatitis http://purl.obolibrary.org/obo/MONDO_0002251

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T288 159-161 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T289 233-235 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T290 233-235 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T291 449-457 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T292 477-482 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T293 493-498 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T294 508-510 http://purl.obolibrary.org/obo/CLO_0008933 denotes S5
T295 579-581 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T296 699-701 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T297 699-701 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T362 233-235 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T363 279-286 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T364 348-350 Chemical denotes S3 http://purl.obolibrary.org/obo/CHEBI_29388
T365 395-404 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T366 434-436 Chemical denotes S4 http://purl.obolibrary.org/obo/CHEBI_29401
T367 439-448 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T368 508-510 Chemical denotes S5 http://purl.obolibrary.org/obo/CHEBI_29386
T369 699-701 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T370 754-756 Chemical denotes S3 http://purl.obolibrary.org/obo/CHEBI_29388

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T29 279-297 http://purl.obolibrary.org/obo/GO_0050821 denotes protein sequesters
T30 279-297 http://purl.obolibrary.org/obo/GO_0045185 denotes protein sequesters

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T6 483-492 Phenotype denotes hepatitis http://purl.obolibrary.org/obo/HP_0012115

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T311 0-790 Sentence denotes The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acs.jmedchem.9b01913.Dimeric conformation of MERS-CoV N-NTD (Figure S1); LibDock pose of dimeric MERS-CoV N-NTD with potent compounds (Figure S2); P3-induced aggregation of the MERS-CoV N protein sequesters the RNA-binding region on the N-CTD dimer (Figure S3); potential target sites for broad-spectrum antiviral compound development (Figure S4); antiviral activity of P3 against MHV (mouse hepatitis virus) (Figure S5); crystallographic data collection and refinement statistics (Table S1); pW43 docking pose with chemical structures, docking scores, and biochemical properties of 17 potential hits (Table S2); primers used for mutagenesis in this study (Table S3); molecular formula strings (PDF)

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
631 136-144 Species denotes MERS-CoV Tax:1335626
632 188-196 Species denotes MERS-CoV Tax:1335626
633 268-276 Species denotes MERS-CoV Tax:1335626
634 477-498 Species denotes mouse hepatitis virus Tax:11138
635 472-475 Species denotes MHV Tax:11138