PMC:7094172 / 33-823
Annnotations
LitCovid-PMC-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T21 | 209-213 | CHEBI:23888;CHEBI:23888 | denotes | drug |
T20 | 476-482 | SO:0000417 | denotes | domain |
T19 | 490-498 | SP_9 | denotes | MERS-CoV |
T18 | 499-519 | PG_4 | denotes | nucleocapsid protein |
T17 | 521-529 | SP_9 | denotes | MERS-CoV |
T16 | 612-616 | CHEBI:23888;CHEBI:23888 | denotes | drug |
T15 | 724-742 | CHEBI:41237;CHEBI:41237 | denotes | 5-benzyloxygramine |
T14 | 752-761 | PG_4 | denotes | N protein |
T22 | 90-94 | CHEBI:36044;CHEBI:36044 | denotes | Drug |
T23 | 55-67 | GO:0000786 | denotes | Nucleocapsid |
T24 | 43-54 | NCBITaxon:11118 | denotes | Coronavirus |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T1 | 11-18 | Body_part | denotes | Protein | http://purl.org/sig/ont/fma/fma67257 |
T2 | 19-26 | Body_part | denotes | Protein | http://purl.org/sig/ont/fma/fma67257 |
T3 | 68-76 | Body_part | denotes | Proteins | http://purl.org/sig/ont/fma/fma67257 |
T4 | 145-152 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T5 | 153-160 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T6 | 512-519 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T7 | 754-761 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 532-535 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 184-185 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T2 | 248-251 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T3 | 259-266 | http://purl.obolibrary.org/obo/CLO_0009985 | denotes | focused |
T4 | 380-381 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T5 | 559-560 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T6 | 583-589 | http://purl.obolibrary.org/obo/UBERON_0002553 | denotes | cavity |
T7 | 746-747 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T1 | 11-18 | Chemical | denotes | Protein | http://purl.obolibrary.org/obo/CHEBI_16541 |
T2 | 19-26 | Chemical | denotes | Protein | http://purl.obolibrary.org/obo/CHEBI_16541 |
T3 | 145-152 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T4 | 153-160 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T5 | 209-213 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
T6 | 512-519 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T7 | 612-616 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
T8 | 754-761 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T9 | 762-765 | Chemical | denotes | PPI | http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614 |
T11 | 778-788 | Chemical | denotes | stabilizer | http://purl.obolibrary.org/obo/CHEBI_77966 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2 | 103-111 | Sentence | denotes | Abstract |
T3 | 112-224 | Sentence | denotes | Structure-based stabilization of protein–protein interactions (PPIs) is a promising strategy for drug discovery. |
T4 | 225-359 | Sentence | denotes | However, this approach has mainly focused on the stabilization of native PPIs, and non-native PPIs have received little consideration. |
T5 | 360-537 | Sentence | denotes | Here, we identified a non-native interaction interface on the three-dimensional dimeric structure of the N-terminal domain of the MERS-CoV nucleocapsid protein (MERS-CoV N-NTD). |
T6 | 538-627 | Sentence | denotes | The interface formed a conserved hydrophobic cavity suitable for targeted drug screening. |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
1 | 43-54 | Species | denotes | Coronavirus | Tax:11118 |
8 | 490-498 | Species | denotes | MERS-CoV | Tax:1335626 |
9 | 521-529 | Species | denotes | MERS-CoV | Tax:1335626 |
10 | 724-742 | Chemical | denotes | 5-benzyloxygramine | MESH:C006736 |