PMC:7091888 / 577-943 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7091888","sourcedb":"PMC","sourceid":"7091888","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7091888","text":"viral attachment, fusion and entry, and serves as a target for development of antibodies, entry inhibitors and vaccines. Here, we identified the receptor-binding domain (RBD) in SARS-CoV-2 S protein and found that the RBD protein bound strongly to human and bat angiotensin-converting enzyme 2 (ACE2) receptors. SARS-CoV-2 RBD exhibited significantly higher binding ","tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"30","span":{"begin":262,"end":293},"obj":"Gene"},{"id":"31","span":{"begin":295,"end":299},"obj":"Gene"},{"id":"35","span":{"begin":189,"end":190},"obj":"Gene"},{"id":"41","span":{"begin":178,"end":188},"obj":"Species"},{"id":"42","span":{"begin":248,"end":253},"obj":"Species"},{"id":"43","span":{"begin":312,"end":322},"obj":"Species"}],"attributes":[{"id":"A30","pred":"tao:has_database_id","subj":"30","obj":"Gene:59272"},{"id":"A31","pred":"tao:has_database_id","subj":"31","obj":"Gene:59272"},{"id":"A35","pred":"tao:has_database_id","subj":"35","obj":"Gene:43740568"},{"id":"A41","pred":"tao:has_database_id","subj":"41","obj":"Tax:2697049"},{"id":"A42","pred":"tao:has_database_id","subj":"42","obj":"Tax:9606"},{"id":"A43","pred":"tao:has_database_id","subj":"43","obj":"Tax:2697049"},{"subj":"30","pred":"source","obj":"LitCovid-PubTator"},{"subj":"31","pred":"source","obj":"LitCovid-PubTator"},{"subj":"35","pred":"source","obj":"LitCovid-PubTator"},{"subj":"41","pred":"source","obj":"LitCovid-PubTator"},{"subj":"42","pred":"source","obj":"LitCovid-PubTator"},{"subj":"43","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T3","span":{"begin":191,"end":198},"obj":"Body_part"},{"id":"T4","span":{"begin":222,"end":229},"obj":"Body_part"}],"attributes":[{"id":"A3","pred":"fma_id","subj":"T3","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma67257"},{"subj":"T3","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T4","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T8","span":{"begin":178,"end":186},"obj":"Disease"},{"id":"T9","span":{"begin":178,"end":182},"obj":"Disease"},{"id":"T10","span":{"begin":312,"end":320},"obj":"Disease"},{"id":"T11","span":{"begin":312,"end":316},"obj":"Disease"}],"attributes":[{"id":"A8","pred":"mondo_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A9","pred":"mondo_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A10","pred":"mondo_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A11","pred":"mondo_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"subj":"T8","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T9","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T10","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T11","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T4","span":{"begin":50,"end":51},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T5","span":{"begin":248,"end":253},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T6","span":{"begin":258,"end":261},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9397"}],"attributes":[{"subj":"T4","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T5","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T6","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T4","span":{"begin":96,"end":106},"obj":"Chemical"},{"id":"T5","span":{"begin":191,"end":198},"obj":"Chemical"},{"id":"T6","span":{"begin":222,"end":229},"obj":"Chemical"},{"id":"T7","span":{"begin":262,"end":273},"obj":"Chemical"}],"attributes":[{"id":"A4","pred":"chebi_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A5","pred":"chebi_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A6","pred":"chebi_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A7","pred":"chebi_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_48433"},{"subj":"T4","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T5","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T6","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T7","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T5","span":{"begin":121,"end":311},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T5","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#ece993","default":true},{"id":"LitCovid-PD-FMA-UBERON","color":"#cf93ec"},{"id":"LitCovid-PD-MONDO","color":"#93ecb5"},{"id":"LitCovid-PD-CLO","color":"#ec9b93"},{"id":"LitCovid-PD-CHEBI","color":"#93a4ec"},{"id":"LitCovid-sentences","color":"#beec93"}]}]}}