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PMC:7091888 / 14427-15676 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
564 62-66 Gene denotes ACE2 Gene:59272
565 131-136 Gene denotes hACE2 Gene:59272
566 145-149 Gene denotes ACE2 Gene:59272
567 205-210 Gene denotes hACE2 Gene:59272
568 266-271 Gene denotes hACE2 Gene:59272
569 504-514 Gene denotes bACE2/293T Gene:25825
570 535-545 Gene denotes hACE2/293T Gene:59272
571 657-667 Gene denotes hACE2/293T Gene:59272
572 880-890 Gene denotes bACE2/293T Gene:25825
573 899-909 Gene denotes hACE2/293T Gene:59272
574 1080-1085 Gene denotes hACE2 Gene:59272
575 14-24 Species denotes SARS-CoV-2 Tax:2697049
576 48-53 Species denotes human Tax:9606
577 105-115 Species denotes SARS-CoV-2 Tax:2697049
578 308-318 Species denotes SARS-CoV-2 Tax:2697049
579 371-379 Species denotes SARS-CoV Tax:694009
580 388-396 Species denotes MERS-CoV Tax:1335626
581 458-468 Species denotes SARS-CoV-2 Tax:2697049
582 592-600 Species denotes SARS-CoV Tax:694009
583 716-724 Species denotes MERS-CoV Tax:1335626
584 854-864 Species denotes SARS-CoV-2 Tax:2697049
585 992-1002 Species denotes SARS-CoV-2 Tax:2697049
586 1019-1027 Species denotes SARS-CoV Tax:694009
587 628-638 Gene denotes bACE2/293T Gene:25825
588 171-175 CellLine denotes 293T CVCL:0063
589 221-225 CellLine denotes 293T CVCL:0063

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T104 29-36 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T105 176-181 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T106 226-231 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T107 323-330 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T108 401-409 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T109 473-480 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T110 563-568 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T111 605-612 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T112 683-688 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T113 729-736 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T114 784-789 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T115 869-876 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T116 915-920 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T117 1041-1045 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T230 14-22 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T231 14-18 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T232 105-113 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T233 105-109 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T234 308-316 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T235 308-312 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T236 371-379 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T237 371-375 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T238 458-466 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T239 458-462 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T240 592-600 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T241 592-596 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T242 854-862 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T243 854-858 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T244 992-1000 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T245 992-996 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T246 1019-1027 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T247 1019-1023 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T263 48-53 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T264 58-61 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T265 141-144 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T266 171-175 http://purl.obolibrary.org/obo/CLO_0050894 denotes 293T
T267 171-175 http://purl.obolibrary.org/obo/CLO_0051650 denotes 293T
T268 171-175 http://purl.obolibrary.org/obo/CLO_0052052 denotes 293T
T269 176-181 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T270 221-225 http://purl.obolibrary.org/obo/CLO_0050894 denotes 293T
T271 221-225 http://purl.obolibrary.org/obo/CLO_0051650 denotes 293T
T272 221-225 http://purl.obolibrary.org/obo/CLO_0052052 denotes 293T
T273 226-231 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T274 510-514 http://purl.obolibrary.org/obo/CLO_0050894 denotes 293T
T275 510-514 http://purl.obolibrary.org/obo/CLO_0051650 denotes 293T
T276 510-514 http://purl.obolibrary.org/obo/CLO_0052052 denotes 293T
T277 516-517 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T278 541-545 http://purl.obolibrary.org/obo/CLO_0050894 denotes 293T
T279 541-545 http://purl.obolibrary.org/obo/CLO_0051650 denotes 293T
T280 541-545 http://purl.obolibrary.org/obo/CLO_0052052 denotes 293T
T281 563-568 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T282 634-638 http://purl.obolibrary.org/obo/CLO_0050894 denotes 293T
T283 634-638 http://purl.obolibrary.org/obo/CLO_0051650 denotes 293T
T284 634-638 http://purl.obolibrary.org/obo/CLO_0052052 denotes 293T
T285 640-641 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T286 663-667 http://purl.obolibrary.org/obo/CLO_0050894 denotes 293T
T287 663-667 http://purl.obolibrary.org/obo/CLO_0051650 denotes 293T
T288 663-667 http://purl.obolibrary.org/obo/CLO_0052052 denotes 293T
T289 683-688 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T290 702-703 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T291 784-789 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T292 791-792 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T293 886-890 http://purl.obolibrary.org/obo/CLO_0050894 denotes 293T
T294 886-890 http://purl.obolibrary.org/obo/CLO_0051650 denotes 293T
T295 886-890 http://purl.obolibrary.org/obo/CLO_0052052 denotes 293T
T296 905-909 http://purl.obolibrary.org/obo/CLO_0050894 denotes 293T
T297 905-909 http://purl.obolibrary.org/obo/CLO_0051650 denotes 293T
T298 905-909 http://purl.obolibrary.org/obo/CLO_0052052 denotes 293T
T299 915-920 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T300 1041-1045 http://purl.obolibrary.org/obo/GO_0005623 denotes cell

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T65 29-36 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T66 323-330 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T67 401-409 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T68 473-480 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T69 605-612 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T70 729-736 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T71 869-876 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T85 78-220 Sentence denotes Flow cytometry analysis of SARS-CoV-2 RBD binding to hACE2 and bat ACE2 (bACE2) receptors in 293T cells transiently expressing hACE2 or bACE2.
T86 221-370 Sentence denotes 293T cells were transiently transfected with hACE2 or bACE2 plasmid and incubated with SARS-CoV-2 RBD protein at various concentrations for analysis.
T87 371-432 Sentence denotes SARS-CoV RBD and MERS-CoV RBD proteins were used as controls.
T88 433-580 Sentence denotes Representative images of SARS-CoV-2 RBD protein (2.5 μg/ml) binding to bACE2/293T (a, black line), or hACE2/293T (c, black line), cells were shown.
T89 581-715 Sentence denotes Binding of SARS-CoV RBD protein (2.5 μg/ml) to bACE2/293T (b, red line), or hACE2/293T (d, red line), cells were used as a comparison.
T90 716-948 Sentence denotes MERS-CoV RBD protein (green line) and mock-incubated (gray shading) cells (a–d) were included as controls. e, f Dose-dependent binding of SARS-CoV-2 RBD protein to bACE2/293T (e), or hACE2/293T (f), cells by flow cytometry analysis.
T91 949-1140 Sentence denotes Significant differences between binding of SARS-CoV-2 RBD (black) and SARS-CoV RBD (red) to cell-associated bACE2 receptor (e), or hACE2 receptor (f) were identified based on the EC50 values.
T92 1141-1189 Sentence denotes The data are presented as mean ± s.e.m. (n = 4).
T93 1190-1249 Sentence denotes Experiments were repeated twice and yielded similar results