PMC:7091888 / 0-1536
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
1 | 57-79 | Species | denotes | 2019 novel coronavirus | Tax:2697049 |
30 | 839-870 | Gene | denotes | angiotensin-converting enzyme 2 | Gene:59272 |
31 | 872-876 | Gene | denotes | ACE2 | Gene:59272 |
32 | 955-959 | Gene | denotes | ACE2 | Gene:59272 |
33 | 1076-1080 | Gene | denotes | ACE2 | Gene:59272 |
34 | 525-530 | Gene | denotes | spike | Gene:43740568 |
35 | 766-767 | Gene | denotes | S | Gene:43740568 |
36 | 405-452 | Species | denotes | severe acute respiratory syndrome coronavirus 2 | Tax:2697049 |
37 | 454-464 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
38 | 481-503 | Species | denotes | 2019 novel coronavirus | Tax:2697049 |
39 | 505-514 | Species | denotes | 2019-nCoV | Tax:2697049 |
40 | 521-524 | Species | denotes | CoV | Tax:11118 |
41 | 755-765 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
42 | 825-830 | Species | denotes | human | Tax:9606 |
43 | 889-899 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
44 | 974-982 | Species | denotes | SARS-CoV | Tax:694009 |
45 | 1041-1051 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
46 | 1060-1068 | Species | denotes | SARS-CoV | Tax:694009 |
47 | 1146-1154 | Species | denotes | SARS-CoV | Tax:694009 |
48 | 1202-1212 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
49 | 1230-1238 | Species | denotes | SARS-CoV | Tax:694009 |
50 | 1283-1293 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
51 | 1331-1339 | Species | denotes | SARS-CoV | Tax:694009 |
52 | 1377-1387 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
53 | 194-218 | Disease | denotes | Coronavirus Disease 2019 | MESH:C000657245 |
54 | 220-228 | Disease | denotes | COVID-19 | MESH:C000657245 |
55 | 371-380 | Disease | denotes | infection | MESH:D007239 |
56 | 1121-1130 | Disease | denotes | infection | MESH:D007239 |
57 | 1392-1410 | Disease | denotes | SARS-CoV infection | MESH:C000657245 |
92 | 1450-1455 | Species | denotes | human | Tax:9606 |
93 | 1456-1469 | Species | denotes | coronaviruses | Tax:11118 |
94 | 1471-1475 | Species | denotes | CoVs | Tax:11118 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T1 | 116-123 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T2 | 535-542 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T3 | 768-775 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T4 | 799-806 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T5 | 1092-1097 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T6 | 1139-1144 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T7 | 1217-1224 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 194-218 | Disease | denotes | Coronavirus Disease 2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T2 | 220-228 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T3 | 371-380 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T4 | 405-452 | Disease | denotes | severe acute respiratory syndrome coronavirus 2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T5 | 405-438 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
T6 | 454-462 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T7 | 454-458 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T8 | 755-763 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T9 | 755-759 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T10 | 889-897 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T11 | 889-893 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T12 | 974-982 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T13 | 974-978 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T14 | 1041-1049 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T15 | 1041-1045 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T16 | 1060-1068 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T17 | 1060-1064 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T18 | 1121-1130 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T19 | 1146-1154 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T20 | 1146-1150 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T21 | 1202-1210 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T22 | 1202-1206 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T23 | 1230-1238 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T24 | 1230-1234 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T25 | 1283-1291 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T26 | 1283-1287 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T27 | 1331-1339 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T28 | 1331-1335 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T29 | 1377-1385 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T30 | 1377-1381 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T31 | 1392-1410 | Disease | denotes | SARS-CoV infection | http://purl.obolibrary.org/obo/MONDO_0005091 |
T32 | 1392-1396 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T33 | 1401-1410 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 127-128 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T2 | 230-233 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T3 | 240-241 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T4 | 627-628 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T5 | 825-830 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T6 | 835-838 | http://purl.obolibrary.org/obo/NCBITaxon_9397 | denotes | bat |
T7 | 1092-1097 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T8 | 1139-1144 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T9 | 1450-1455 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T1 | 116-123 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T2 | 146-155 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
T3 | 535-542 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T4 | 673-683 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
T5 | 768-775 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T6 | 799-806 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T7 | 839-850 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
T8 | 1217-1224 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-167 | Sentence | denotes | Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine |
T2 | 169-177 | Sentence | denotes | Abstract |
T3 | 178-516 | Sentence | denotes | The outbreak of Coronavirus Disease 2019 (COVID-19) has posed a serious threat to global public health, calling for the development of safe and effective prophylactics and therapeutics against infection of its causative agent, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also known as 2019 novel coronavirus (2019-nCoV). |
T4 | 517-697 | Sentence | denotes | The CoV spike (S) protein plays the most important roles in viral attachment, fusion and entry, and serves as a target for development of antibodies, entry inhibitors and vaccines. |
T5 | 698-888 | Sentence | denotes | Here, we identified the receptor-binding domain (RBD) in SARS-CoV-2 S protein and found that the RBD protein bound strongly to human and bat angiotensin-converting enzyme 2 (ACE2) receptors. |
T6 | 889-1145 | Sentence | denotes | SARS-CoV-2 RBD exhibited significantly higher binding affinity to ACE2 receptor than SARS-CoV RBD and could block the binding and, hence, attachment of SARS-CoV-2 RBD and SARS-CoV RBD to ACE2-expressing cells, thus inhibiting their infection to host cells. |
T7 | 1146-1411 | Sentence | denotes | SARS-CoV RBD-specific antibodies could cross-react with SARS-CoV-2 RBD protein, and SARS-CoV RBD-induced antisera could cross-neutralize SARS-CoV-2, suggesting the potential to develop SARS-CoV RBD-based vaccines for prevention of SARS-CoV-2 and SARS-CoV infection. |
T8 | 1413-1425 | Sentence | denotes | Introduction |