PMC:7088323 / 15672-17041
Annnotations
LitCovid-PD-FMA-UBERON
{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T52","span":{"begin":62,"end":66},"obj":"Body_part"},{"id":"T53","span":{"begin":957,"end":973},"obj":"Body_part"},{"id":"T54","span":{"begin":1150,"end":1167},"obj":"Body_part"},{"id":"T55","span":{"begin":1353,"end":1369},"obj":"Body_part"}],"attributes":[{"id":"A52","pred":"fma_id","subj":"T52","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A53","pred":"fma_id","subj":"T53","obj":"http://purl.org/sig/ont/fma/fma7333"},{"id":"A54","pred":"fma_id","subj":"T54","obj":"http://purl.org/sig/ont/fma/fma7383"},{"id":"A55","pred":"fma_id","subj":"T55","obj":"http://purl.org/sig/ont/fma/fma7337"}],"text":"Air bubble sign refers to a small air-containing space in the lung (Fig. 5a), which might be the pathological dilation of a physiological space or a cross section of the bronchiolectasis, or associated with the process of consolidation resorption. Shi et al termed this sign as round cystic change in their study [18], while Kong et al reported it as cavity sign [32]. However, given the displayed pictures in their studies and the definition of cyst and cavity [26], we believe it may be more appropriate to term this small bubble-like air-containing space as air bubble sign.\nFig. 5 a A 49-year-old male COVID-19 patient presenting fever with diarrhea for 3 days. CT scan shows a patchy GGO (red frame) with an air bubble sign (white arrow) in the apicoposterior segment of the upper left lobe. b A 76-year-old female COVID-19 patient presenting fever with cough for 4 days. CT scan shows an irregular nodule (white arrow) in the posterior segment of the right upper lobe. c A 46-year-old male COVID-19 patient presenting fever with dry cough for 5 days. CT scan shows a solid nodule surrounded by a ground glass halo in the lateral segment of the right middle lobe (red frame). d A 66-year-old woman confirmed with COVID-19 presenting fever and myalgia for 7 days. CT scan shows a reversed halo sign (red frame) in the posterior basal segment of the right lower lobe"}
LitCovid-PD-UBERON
{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T38","span":{"begin":62,"end":66},"obj":"Body_part"},{"id":"T39","span":{"begin":791,"end":795},"obj":"Body_part"},{"id":"T40","span":{"begin":969,"end":973},"obj":"Body_part"},{"id":"T41","span":{"begin":1163,"end":1167},"obj":"Body_part"},{"id":"T42","span":{"begin":1365,"end":1369},"obj":"Body_part"}],"attributes":[{"id":"A38","pred":"uberon_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A39","pred":"uberon_id","subj":"T39","obj":"http://purl.obolibrary.org/obo/UBERON_3010752"},{"id":"A40","pred":"uberon_id","subj":"T40","obj":"http://purl.obolibrary.org/obo/UBERON_3010752"},{"id":"A41","pred":"uberon_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/UBERON_3010752"},{"id":"A42","pred":"uberon_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/UBERON_3010752"}],"text":"Air bubble sign refers to a small air-containing space in the lung (Fig. 5a), which might be the pathological dilation of a physiological space or a cross section of the bronchiolectasis, or associated with the process of consolidation resorption. Shi et al termed this sign as round cystic change in their study [18], while Kong et al reported it as cavity sign [32]. However, given the displayed pictures in their studies and the definition of cyst and cavity [26], we believe it may be more appropriate to term this small bubble-like air-containing space as air bubble sign.\nFig. 5 a A 49-year-old male COVID-19 patient presenting fever with diarrhea for 3 days. CT scan shows a patchy GGO (red frame) with an air bubble sign (white arrow) in the apicoposterior segment of the upper left lobe. b A 76-year-old female COVID-19 patient presenting fever with cough for 4 days. CT scan shows an irregular nodule (white arrow) in the posterior segment of the right upper lobe. c A 46-year-old male COVID-19 patient presenting fever with dry cough for 5 days. CT scan shows a solid nodule surrounded by a ground glass halo in the lateral segment of the right middle lobe (red frame). d A 66-year-old woman confirmed with COVID-19 presenting fever and myalgia for 7 days. CT scan shows a reversed halo sign (red frame) in the posterior basal segment of the right lower lobe"}
LitCovid-PD-MONDO
{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T89","span":{"begin":606,"end":614},"obj":"Disease"},{"id":"T90","span":{"begin":645,"end":653},"obj":"Disease"},{"id":"T91","span":{"begin":820,"end":828},"obj":"Disease"},{"id":"T92","span":{"begin":996,"end":1004},"obj":"Disease"},{"id":"T93","span":{"begin":1218,"end":1226},"obj":"Disease"}],"attributes":[{"id":"A89","pred":"mondo_id","subj":"T89","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A90","pred":"mondo_id","subj":"T90","obj":"http://purl.obolibrary.org/obo/MONDO_0001673"},{"id":"A91","pred":"mondo_id","subj":"T91","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A92","pred":"mondo_id","subj":"T92","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A93","pred":"mondo_id","subj":"T93","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"Air bubble sign refers to a small air-containing space in the lung (Fig. 5a), which might be the pathological dilation of a physiological space or a cross section of the bronchiolectasis, or associated with the process of consolidation resorption. Shi et al termed this sign as round cystic change in their study [18], while Kong et al reported it as cavity sign [32]. However, given the displayed pictures in their studies and the definition of cyst and cavity [26], we believe it may be more appropriate to term this small bubble-like air-containing space as air bubble sign.\nFig. 5 a A 49-year-old male COVID-19 patient presenting fever with diarrhea for 3 days. CT scan shows a patchy GGO (red frame) with an air bubble sign (white arrow) in the apicoposterior segment of the upper left lobe. b A 76-year-old female COVID-19 patient presenting fever with cough for 4 days. CT scan shows an irregular nodule (white arrow) in the posterior segment of the right upper lobe. c A 46-year-old male COVID-19 patient presenting fever with dry cough for 5 days. CT scan shows a solid nodule surrounded by a ground glass halo in the lateral segment of the right middle lobe (red frame). d A 66-year-old woman confirmed with COVID-19 presenting fever and myalgia for 7 days. CT scan shows a reversed halo sign (red frame) in the posterior basal segment of the right lower lobe"}
LitCovid-PD-CLO
{"project":"LitCovid-PD-CLO","denotations":[{"id":"T173","span":{"begin":26,"end":27},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T174","span":{"begin":62,"end":66},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T175","span":{"begin":62,"end":66},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T176","span":{"begin":122,"end":123},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T177","span":{"begin":147,"end":148},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T178","span":{"begin":314,"end":316},"obj":"http://purl.obolibrary.org/obo/CLO_0050510"},{"id":"T179","span":{"begin":351,"end":357},"obj":"http://purl.obolibrary.org/obo/UBERON_0002553"},{"id":"T180","span":{"begin":455,"end":461},"obj":"http://purl.obolibrary.org/obo/UBERON_0002553"},{"id":"T181","span":{"begin":585,"end":588},"obj":"http://purl.obolibrary.org/obo/CLO_0001627"},{"id":"T182","span":{"begin":601,"end":605},"obj":"http://purl.obolibrary.org/obo/UBERON_0003101"},{"id":"T183","span":{"begin":601,"end":605},"obj":"http://www.ebi.ac.uk/efo/EFO_0000970"},{"id":"T184","span":{"begin":680,"end":681},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T185","span":{"begin":797,"end":798},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T186","span":{"begin":799,"end":800},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T187","span":{"begin":813,"end":819},"obj":"http://purl.obolibrary.org/obo/UBERON_0003100"},{"id":"T188","span":{"begin":932,"end":941},"obj":"http://purl.obolibrary.org/obo/UBERON_0001353"},{"id":"T189","span":{"begin":977,"end":978},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T190","span":{"begin":991,"end":995},"obj":"http://purl.obolibrary.org/obo/UBERON_0003101"},{"id":"T191","span":{"begin":991,"end":995},"obj":"http://www.ebi.ac.uk/efo/EFO_0000970"},{"id":"T192","span":{"begin":1071,"end":1072},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T193","span":{"begin":1100,"end":1101},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T194","span":{"begin":1181,"end":1184},"obj":"http://www.ebi.ac.uk/efo/EFO_0000265"},{"id":"T195","span":{"begin":1282,"end":1283},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T196","span":{"begin":1322,"end":1331},"obj":"http://purl.obolibrary.org/obo/UBERON_0001353"}],"text":"Air bubble sign refers to a small air-containing space in the lung (Fig. 5a), which might be the pathological dilation of a physiological space or a cross section of the bronchiolectasis, or associated with the process of consolidation resorption. Shi et al termed this sign as round cystic change in their study [18], while Kong et al reported it as cavity sign [32]. However, given the displayed pictures in their studies and the definition of cyst and cavity [26], we believe it may be more appropriate to term this small bubble-like air-containing space as air bubble sign.\nFig. 5 a A 49-year-old male COVID-19 patient presenting fever with diarrhea for 3 days. CT scan shows a patchy GGO (red frame) with an air bubble sign (white arrow) in the apicoposterior segment of the upper left lobe. b A 76-year-old female COVID-19 patient presenting fever with cough for 4 days. CT scan shows an irregular nodule (white arrow) in the posterior segment of the right upper lobe. c A 46-year-old male COVID-19 patient presenting fever with dry cough for 5 days. CT scan shows a solid nodule surrounded by a ground glass halo in the lateral segment of the right middle lobe (red frame). d A 66-year-old woman confirmed with COVID-19 presenting fever and myalgia for 7 days. CT scan shows a reversed halo sign (red frame) in the posterior basal segment of the right lower lobe"}
LitCovid-PD-CHEBI
{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T14","span":{"begin":601,"end":605},"obj":"Chemical"},{"id":"T15","span":{"begin":991,"end":995},"obj":"Chemical"}],"attributes":[{"id":"A14","pred":"chebi_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_30780"},{"id":"A15","pred":"chebi_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/CHEBI_30780"}],"text":"Air bubble sign refers to a small air-containing space in the lung (Fig. 5a), which might be the pathological dilation of a physiological space or a cross section of the bronchiolectasis, or associated with the process of consolidation resorption. Shi et al termed this sign as round cystic change in their study [18], while Kong et al reported it as cavity sign [32]. However, given the displayed pictures in their studies and the definition of cyst and cavity [26], we believe it may be more appropriate to term this small bubble-like air-containing space as air bubble sign.\nFig. 5 a A 49-year-old male COVID-19 patient presenting fever with diarrhea for 3 days. CT scan shows a patchy GGO (red frame) with an air bubble sign (white arrow) in the apicoposterior segment of the upper left lobe. b A 76-year-old female COVID-19 patient presenting fever with cough for 4 days. CT scan shows an irregular nodule (white arrow) in the posterior segment of the right upper lobe. c A 46-year-old male COVID-19 patient presenting fever with dry cough for 5 days. CT scan shows a solid nodule surrounded by a ground glass halo in the lateral segment of the right middle lobe (red frame). d A 66-year-old woman confirmed with COVID-19 presenting fever and myalgia for 7 days. CT scan shows a reversed halo sign (red frame) in the posterior basal segment of the right lower lobe"}
LitCovid-PD-HP
{"project":"LitCovid-PD-HP","denotations":[{"id":"T44","span":{"begin":170,"end":186},"obj":"Phenotype"},{"id":"T45","span":{"begin":634,"end":639},"obj":"Phenotype"},{"id":"T46","span":{"begin":645,"end":653},"obj":"Phenotype"},{"id":"T47","span":{"begin":848,"end":853},"obj":"Phenotype"},{"id":"T48","span":{"begin":859,"end":864},"obj":"Phenotype"},{"id":"T49","span":{"begin":1024,"end":1029},"obj":"Phenotype"},{"id":"T50","span":{"begin":1035,"end":1044},"obj":"Phenotype"},{"id":"T51","span":{"begin":1238,"end":1243},"obj":"Phenotype"},{"id":"T52","span":{"begin":1248,"end":1255},"obj":"Phenotype"},{"id":"T53","span":{"begin":1284,"end":1302},"obj":"Phenotype"}],"attributes":[{"id":"A44","pred":"hp_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/HP_0410397"},{"id":"A45","pred":"hp_id","subj":"T45","obj":"http://purl.obolibrary.org/obo/HP_0001945"},{"id":"A46","pred":"hp_id","subj":"T46","obj":"http://purl.obolibrary.org/obo/HP_0002014"},{"id":"A47","pred":"hp_id","subj":"T47","obj":"http://purl.obolibrary.org/obo/HP_0001945"},{"id":"A48","pred":"hp_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/HP_0012735"},{"id":"A49","pred":"hp_id","subj":"T49","obj":"http://purl.obolibrary.org/obo/HP_0001945"},{"id":"A50","pred":"hp_id","subj":"T50","obj":"http://purl.obolibrary.org/obo/HP_0031246"},{"id":"A51","pred":"hp_id","subj":"T51","obj":"http://purl.obolibrary.org/obo/HP_0001945"},{"id":"A52","pred":"hp_id","subj":"T52","obj":"http://purl.obolibrary.org/obo/HP_0003326"},{"id":"A53","pred":"hp_id","subj":"T53","obj":"http://purl.obolibrary.org/obo/HP_0032983"}],"text":"Air bubble sign refers to a small air-containing space in the lung (Fig. 5a), which might be the pathological dilation of a physiological space or a cross section of the bronchiolectasis, or associated with the process of consolidation resorption. Shi et al termed this sign as round cystic change in their study [18], while Kong et al reported it as cavity sign [32]. However, given the displayed pictures in their studies and the definition of cyst and cavity [26], we believe it may be more appropriate to term this small bubble-like air-containing space as air bubble sign.\nFig. 5 a A 49-year-old male COVID-19 patient presenting fever with diarrhea for 3 days. CT scan shows a patchy GGO (red frame) with an air bubble sign (white arrow) in the apicoposterior segment of the upper left lobe. b A 76-year-old female COVID-19 patient presenting fever with cough for 4 days. CT scan shows an irregular nodule (white arrow) in the posterior segment of the right upper lobe. c A 46-year-old male COVID-19 patient presenting fever with dry cough for 5 days. CT scan shows a solid nodule surrounded by a ground glass halo in the lateral segment of the right middle lobe (red frame). d A 66-year-old woman confirmed with COVID-19 presenting fever and myalgia for 7 days. CT scan shows a reversed halo sign (red frame) in the posterior basal segment of the right lower lobe"}
LitCovid-sentences
{"project":"LitCovid-sentences","denotations":[{"id":"T112","span":{"begin":0,"end":247},"obj":"Sentence"},{"id":"T113","span":{"begin":248,"end":368},"obj":"Sentence"},{"id":"T114","span":{"begin":369,"end":577},"obj":"Sentence"},{"id":"T115","span":{"begin":578,"end":665},"obj":"Sentence"},{"id":"T116","span":{"begin":666,"end":876},"obj":"Sentence"},{"id":"T117","span":{"begin":877,"end":1056},"obj":"Sentence"},{"id":"T118","span":{"begin":1057,"end":1267},"obj":"Sentence"},{"id":"T119","span":{"begin":1268,"end":1369},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Air bubble sign refers to a small air-containing space in the lung (Fig. 5a), which might be the pathological dilation of a physiological space or a cross section of the bronchiolectasis, or associated with the process of consolidation resorption. Shi et al termed this sign as round cystic change in their study [18], while Kong et al reported it as cavity sign [32]. However, given the displayed pictures in their studies and the definition of cyst and cavity [26], we believe it may be more appropriate to term this small bubble-like air-containing space as air bubble sign.\nFig. 5 a A 49-year-old male COVID-19 patient presenting fever with diarrhea for 3 days. CT scan shows a patchy GGO (red frame) with an air bubble sign (white arrow) in the apicoposterior segment of the upper left lobe. b A 76-year-old female COVID-19 patient presenting fever with cough for 4 days. CT scan shows an irregular nodule (white arrow) in the posterior segment of the right upper lobe. c A 46-year-old male COVID-19 patient presenting fever with dry cough for 5 days. CT scan shows a solid nodule surrounded by a ground glass halo in the lateral segment of the right middle lobe (red frame). d A 66-year-old woman confirmed with COVID-19 presenting fever and myalgia for 7 days. CT scan shows a reversed halo sign (red frame) in the posterior basal segment of the right lower lobe"}
0_colil
{"project":"0_colil","denotations":[{"id":"32193638-18195376-54935","span":{"begin":463,"end":465},"obj":"18195376"}],"text":"Air bubble sign refers to a small air-containing space in the lung (Fig. 5a), which might be the pathological dilation of a physiological space or a cross section of the bronchiolectasis, or associated with the process of consolidation resorption. Shi et al termed this sign as round cystic change in their study [18], while Kong et al reported it as cavity sign [32]. However, given the displayed pictures in their studies and the definition of cyst and cavity [26], we believe it may be more appropriate to term this small bubble-like air-containing space as air bubble sign.\nFig. 5 a A 49-year-old male COVID-19 patient presenting fever with diarrhea for 3 days. CT scan shows a patchy GGO (red frame) with an air bubble sign (white arrow) in the apicoposterior segment of the upper left lobe. b A 76-year-old female COVID-19 patient presenting fever with cough for 4 days. CT scan shows an irregular nodule (white arrow) in the posterior segment of the right upper lobe. c A 46-year-old male COVID-19 patient presenting fever with dry cough for 5 days. CT scan shows a solid nodule surrounded by a ground glass halo in the lateral segment of the right middle lobe (red frame). d A 66-year-old woman confirmed with COVID-19 presenting fever and myalgia for 7 days. CT scan shows a reversed halo sign (red frame) in the posterior basal segment of the right lower lobe"}
TEST0
{"project":"TEST0","denotations":[{"id":"32193638-94-100-54935","span":{"begin":463,"end":465},"obj":"[\"18195376\"]"}],"text":"Air bubble sign refers to a small air-containing space in the lung (Fig. 5a), which might be the pathological dilation of a physiological space or a cross section of the bronchiolectasis, or associated with the process of consolidation resorption. Shi et al termed this sign as round cystic change in their study [18], while Kong et al reported it as cavity sign [32]. However, given the displayed pictures in their studies and the definition of cyst and cavity [26], we believe it may be more appropriate to term this small bubble-like air-containing space as air bubble sign.\nFig. 5 a A 49-year-old male COVID-19 patient presenting fever with diarrhea for 3 days. CT scan shows a patchy GGO (red frame) with an air bubble sign (white arrow) in the apicoposterior segment of the upper left lobe. b A 76-year-old female COVID-19 patient presenting fever with cough for 4 days. CT scan shows an irregular nodule (white arrow) in the posterior segment of the right upper lobe. c A 46-year-old male COVID-19 patient presenting fever with dry cough for 5 days. CT scan shows a solid nodule surrounded by a ground glass halo in the lateral segment of the right middle lobe (red frame). d A 66-year-old woman confirmed with COVID-19 presenting fever and myalgia for 7 days. CT scan shows a reversed halo sign (red frame) in the posterior basal segment of the right lower lobe"}
MyTest
{"project":"MyTest","denotations":[{"id":"32193638-18195376-29362788","span":{"begin":463,"end":465},"obj":"18195376"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"Air bubble sign refers to a small air-containing space in the lung (Fig. 5a), which might be the pathological dilation of a physiological space or a cross section of the bronchiolectasis, or associated with the process of consolidation resorption. Shi et al termed this sign as round cystic change in their study [18], while Kong et al reported it as cavity sign [32]. However, given the displayed pictures in their studies and the definition of cyst and cavity [26], we believe it may be more appropriate to term this small bubble-like air-containing space as air bubble sign.\nFig. 5 a A 49-year-old male COVID-19 patient presenting fever with diarrhea for 3 days. CT scan shows a patchy GGO (red frame) with an air bubble sign (white arrow) in the apicoposterior segment of the upper left lobe. b A 76-year-old female COVID-19 patient presenting fever with cough for 4 days. CT scan shows an irregular nodule (white arrow) in the posterior segment of the right upper lobe. c A 46-year-old male COVID-19 patient presenting fever with dry cough for 5 days. CT scan shows a solid nodule surrounded by a ground glass halo in the lateral segment of the right middle lobe (red frame). d A 66-year-old woman confirmed with COVID-19 presenting fever and myalgia for 7 days. CT scan shows a reversed halo sign (red frame) in the posterior basal segment of the right lower lobe"}
2_test
{"project":"2_test","denotations":[{"id":"32193638-18195376-29362788","span":{"begin":463,"end":465},"obj":"18195376"}],"text":"Air bubble sign refers to a small air-containing space in the lung (Fig. 5a), which might be the pathological dilation of a physiological space or a cross section of the bronchiolectasis, or associated with the process of consolidation resorption. Shi et al termed this sign as round cystic change in their study [18], while Kong et al reported it as cavity sign [32]. However, given the displayed pictures in their studies and the definition of cyst and cavity [26], we believe it may be more appropriate to term this small bubble-like air-containing space as air bubble sign.\nFig. 5 a A 49-year-old male COVID-19 patient presenting fever with diarrhea for 3 days. CT scan shows a patchy GGO (red frame) with an air bubble sign (white arrow) in the apicoposterior segment of the upper left lobe. b A 76-year-old female COVID-19 patient presenting fever with cough for 4 days. CT scan shows an irregular nodule (white arrow) in the posterior segment of the right upper lobe. c A 46-year-old male COVID-19 patient presenting fever with dry cough for 5 days. CT scan shows a solid nodule surrounded by a ground glass halo in the lateral segment of the right middle lobe (red frame). d A 66-year-old woman confirmed with COVID-19 presenting fever and myalgia for 7 days. CT scan shows a reversed halo sign (red frame) in the posterior basal segment of the right lower lobe"}
LitCovid-PubTator
{"project":"LitCovid-PubTator","denotations":[{"id":"326","span":{"begin":615,"end":622},"obj":"Species"},{"id":"327","span":{"begin":829,"end":836},"obj":"Species"},{"id":"328","span":{"begin":1005,"end":1012},"obj":"Species"},{"id":"329","span":{"begin":1197,"end":1202},"obj":"Species"},{"id":"330","span":{"begin":606,"end":614},"obj":"Disease"},{"id":"331","span":{"begin":634,"end":639},"obj":"Disease"},{"id":"332","span":{"begin":645,"end":653},"obj":"Disease"},{"id":"333","span":{"begin":820,"end":828},"obj":"Disease"},{"id":"334","span":{"begin":848,"end":853},"obj":"Disease"},{"id":"335","span":{"begin":859,"end":864},"obj":"Disease"},{"id":"336","span":{"begin":996,"end":1004},"obj":"Disease"},{"id":"337","span":{"begin":1024,"end":1029},"obj":"Disease"},{"id":"338","span":{"begin":1035,"end":1044},"obj":"Disease"},{"id":"339","span":{"begin":1218,"end":1226},"obj":"Disease"},{"id":"340","span":{"begin":1238,"end":1243},"obj":"Disease"},{"id":"341","span":{"begin":1248,"end":1255},"obj":"Disease"}],"attributes":[{"id":"A326","pred":"tao:has_database_id","subj":"326","obj":"Tax:9606"},{"id":"A327","pred":"tao:has_database_id","subj":"327","obj":"Tax:9606"},{"id":"A328","pred":"tao:has_database_id","subj":"328","obj":"Tax:9606"},{"id":"A329","pred":"tao:has_database_id","subj":"329","obj":"Tax:9606"},{"id":"A330","pred":"tao:has_database_id","subj":"330","obj":"MESH:C000657245"},{"id":"A331","pred":"tao:has_database_id","subj":"331","obj":"MESH:D005334"},{"id":"A332","pred":"tao:has_database_id","subj":"332","obj":"MESH:D003967"},{"id":"A333","pred":"tao:has_database_id","subj":"333","obj":"MESH:C000657245"},{"id":"A334","pred":"tao:has_database_id","subj":"334","obj":"MESH:D005334"},{"id":"A335","pred":"tao:has_database_id","subj":"335","obj":"MESH:D003371"},{"id":"A336","pred":"tao:has_database_id","subj":"336","obj":"MESH:C000657245"},{"id":"A337","pred":"tao:has_database_id","subj":"337","obj":"MESH:D005334"},{"id":"A338","pred":"tao:has_database_id","subj":"338","obj":"MESH:D003371"},{"id":"A339","pred":"tao:has_database_id","subj":"339","obj":"MESH:C000657245"},{"id":"A340","pred":"tao:has_database_id","subj":"340","obj":"MESH:D005334"},{"id":"A341","pred":"tao:has_database_id","subj":"341","obj":"MESH:D063806"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Air bubble sign refers to a small air-containing space in the lung (Fig. 5a), which might be the pathological dilation of a physiological space or a cross section of the bronchiolectasis, or associated with the process of consolidation resorption. Shi et al termed this sign as round cystic change in their study [18], while Kong et al reported it as cavity sign [32]. However, given the displayed pictures in their studies and the definition of cyst and cavity [26], we believe it may be more appropriate to term this small bubble-like air-containing space as air bubble sign.\nFig. 5 a A 49-year-old male COVID-19 patient presenting fever with diarrhea for 3 days. CT scan shows a patchy GGO (red frame) with an air bubble sign (white arrow) in the apicoposterior segment of the upper left lobe. b A 76-year-old female COVID-19 patient presenting fever with cough for 4 days. CT scan shows an irregular nodule (white arrow) in the posterior segment of the right upper lobe. c A 46-year-old male COVID-19 patient presenting fever with dry cough for 5 days. CT scan shows a solid nodule surrounded by a ground glass halo in the lateral segment of the right middle lobe (red frame). d A 66-year-old woman confirmed with COVID-19 presenting fever and myalgia for 7 days. CT scan shows a reversed halo sign (red frame) in the posterior basal segment of the right lower lobe"}