PMC:7082661 / 2139-5086
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 42 | 579-597 | Gene | denotes | C-reactive protein | Gene:1401 |
| 43 | 33-36 | Species | denotes | boy | Tax:9606 |
| 44 | 52-57 | Disease | denotes | fever | MESH:D005334 |
| 45 | 94-99 | Disease | denotes | Fever | MESH:D005334 |
| 46 | 183-191 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 47 | 333-338 | Disease | denotes | fever | MESH:D005334 |
| 62 | 619-626 | Species | denotes | patient | Tax:9606 |
| 63 | 791-798 | Species | denotes | patient | Tax:9606 |
| 64 | 1158-1166 | Species | denotes | patients | Tax:9606 |
| 65 | 1197-1204 | Species | denotes | patient | Tax:9606 |
| 66 | 1335-1342 | Species | denotes | patient | Tax:9606 |
| 67 | 1372-1382 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 68 | 1432-1442 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 69 | 652-657 | Disease | denotes | Fever | MESH:D005334 |
| 70 | 701-712 | Disease | denotes | A infection | MESH:D007239 |
| 71 | 875-883 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 72 | 1112-1121 | Disease | denotes | pneumonia | MESH:D011014 |
| 73 | 1172-1180 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 74 | 1213-1222 | Disease | denotes | pneumonia | MESH:D011014 |
| 75 | 1470-1479 | Disease | denotes | infection | MESH:D007239 |
| 90 | 2231-2249 | Gene | denotes | C-reactive protein | Gene:1401 |
| 91 | 1642-1649 | Species | denotes | patient | Tax:9606 |
| 92 | 1685-1693 | Species | denotes | patients | Tax:9606 |
| 93 | 1711-1717 | Species | denotes | people | Tax:9606 |
| 94 | 1522-1527 | Disease | denotes | fever | MESH:D005334 |
| 95 | 1592-1597 | Disease | denotes | Fever | MESH:D005334 |
| 96 | 1699-1707 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 97 | 1826-1831 | Disease | denotes | fever | MESH:D005334 |
| 98 | 1866-1886 | Disease | denotes | Respiratory symptoms | MESH:D012818 |
| 99 | 1909-1919 | Disease | denotes | dry throat | MESH:D010608 |
| 100 | 1949-1954 | Disease | denotes | cough | MESH:D003371 |
| 101 | 2023-2029 | Disease | denotes | nausea | MESH:D009325 |
| 102 | 2031-2039 | Disease | denotes | vomiting | MESH:D014839 |
| 103 | 2045-2053 | Disease | denotes | diarrhea | MESH:D003967 |
| 113 | 2648-2658 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 114 | 2690-2700 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 115 | 2762-2772 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 116 | 2864-2871 | Species | denotes | patient | Tax:9606 |
| 117 | 2285-2294 | Disease | denotes | emphysema | MESH:D004646 |
| 118 | 2396-2411 | Disease | denotes | viral pneumonia | |
| 119 | 2502-2511 | Disease | denotes | pneumonia | MESH:D011014 |
| 120 | 2521-2529 | Disease | denotes | infected | MESH:D007239 |
| 121 | 2899-2907 | Disease | denotes | COVID-19 | MESH:C000657245 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T1 | 351-355 | Body_part | denotes | body | http://purl.org/sig/ont/fma/fma256135 |
| T2 | 447-456 | Body_part | denotes | leukocyte | http://purl.org/sig/ont/fma/fma62852 |
| T3 | 476-486 | Body_part | denotes | neutrophil | http://purl.org/sig/ont/fma/fma62860 |
| T4 | 542-553 | Body_part | denotes | lymphocytes | http://purl.org/sig/ont/fma/fma62863 |
| T5 | 590-597 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T6 | 1041-1046 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
| T7 | 1281-1286 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
| T8 | 1304-1310 | Body_part | denotes | throat | http://purl.org/sig/ont/fma/fma228738 |
| T9 | 1545-1549 | Body_part | denotes | body | http://purl.org/sig/ont/fma/fma256135 |
| T10 | 1839-1843 | Body_part | denotes | body | http://purl.org/sig/ont/fma/fma256135 |
| T11 | 1913-1919 | Body_part | denotes | throat | http://purl.org/sig/ont/fma/fma228738 |
| T12 | 1956-1962 | Body_part | denotes | sputum | http://purl.org/sig/ont/fma/fma312401 |
| T13 | 1980-1984 | Body_part | denotes | nose | http://purl.org/sig/ont/fma/fma46472 |
| T14 | 2097-2106 | Body_part | denotes | leukocyte | http://purl.org/sig/ont/fma/fma62852 |
| T15 | 2127-2137 | Body_part | denotes | neutrophil | http://purl.org/sig/ont/fma/fma62860 |
| T16 | 2194-2205 | Body_part | denotes | lymphocytes | http://purl.org/sig/ont/fma/fma62863 |
| T17 | 2242-2249 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T18 | 2269-2274 | Body_part | denotes | Chest | http://purl.org/sig/ont/fma/fma9576 |
| T19 | 2309-2314 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
| T20 | 2357-2373 | Body_part | denotes | right lower lobe | http://purl.org/sig/ont/fma/fma7337 |
| T21 | 2568-2573 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
| T22 | 2598-2604 | Body_part | denotes | throat | http://purl.org/sig/ont/fma/fma228738 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 1304-1310 | Body_part | denotes | throat | http://purl.obolibrary.org/obo/UBERON_0000341 |
| T2 | 1913-1919 | Body_part | denotes | throat | http://purl.obolibrary.org/obo/UBERON_0000341 |
| T3 | 1956-1962 | Body_part | denotes | sputum | http://purl.obolibrary.org/obo/UBERON_0007311 |
| T4 | 1980-1984 | Body_part | denotes | nose | http://purl.obolibrary.org/obo/UBERON_0000004 |
| T5 | 2269-2274 | Body_part | denotes | Chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
| T6 | 2369-2373 | Body_part | denotes | lobe | http://purl.obolibrary.org/obo/UBERON_3010752 |
| T7 | 2598-2604 | Body_part | denotes | throat | http://purl.obolibrary.org/obo/UBERON_0000341 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T15 | 183-191 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T16 | 691-700 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T17 | 703-712 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T18 | 875-883 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T19 | 969-978 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T20 | 1112-1121 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T21 | 1172-1180 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T22 | 1213-1222 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T23 | 1372-1380 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T24 | 1432-1440 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T25 | 1470-1479 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T26 | 1699-1707 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T27 | 1974-1984 | Disease | denotes | runny nose | http://purl.obolibrary.org/obo/MONDO_0003014 |
| T28 | 2045-2053 | Disease | denotes | diarrhea | http://purl.obolibrary.org/obo/MONDO_0001673 |
| T29 | 2285-2294 | Disease | denotes | emphysema | http://purl.obolibrary.org/obo/MONDO_0004849 |
| T30 | 2396-2411 | Disease | denotes | viral pneumonia | http://purl.obolibrary.org/obo/MONDO_0006012 |
| T31 | 2402-2411 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T32 | 2502-2511 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T33 | 2648-2656 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T34 | 2690-2698 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T35 | 2762-2770 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T36 | 2899-2907 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T10 | 251-252 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T11 | 344-345 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T12 | 605-607 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T13 | 701-702 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T14 | 729-730 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T15 | 760-764 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
| T16 | 934-938 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
| T17 | 979-980 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T18 | 1041-1046 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
| T19 | 1048-1049 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T20 | 1281-1286 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
| T21 | 1348-1354 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tested |
| T22 | 1424-1425 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T23 | 1451-1455 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
| T24 | 1489-1490 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T25 | 1491-1493 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 36 |
| T26 | 1747-1748 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T27 | 1837-1838 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T28 | 1980-1984 | http://www.ebi.ac.uk/efo/EFO_0000828 | denotes | nose |
| T29 | 2269-2274 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | Chest |
| T30 | 2309-2314 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
| T31 | 2487-2488 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T32 | 2568-2573 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
| T33 | 2668-2669 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T34 | 2735-2739 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
| T35 | 2741-2742 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T36 | 2781-2789 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test was |
| T37 | 2828-2829 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T38 | 2941-2946 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tests |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T9 | 590-597 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T10 | 747-759 | Chemical | denotes | nucleic acid | http://purl.obolibrary.org/obo/CHEBI_33696 |
| T11 | 755-759 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T12 | 921-933 | Chemical | denotes | nucleic acid | http://purl.obolibrary.org/obo/CHEBI_33696 |
| T13 | 929-933 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
| T14 | 1065-1067 | Chemical | denotes | DL | http://purl.obolibrary.org/obo/CHEBI_68596 |
| T15 | 2242-2249 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T16 | 2430-2432 | Chemical | denotes | DL | http://purl.obolibrary.org/obo/CHEBI_68596 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T2 | 52-57 | Phenotype | denotes | fever | http://purl.obolibrary.org/obo/HP_0001945 |
| T3 | 94-99 | Phenotype | denotes | Fever | http://purl.obolibrary.org/obo/HP_0001945 |
| T4 | 333-338 | Phenotype | denotes | fever | http://purl.obolibrary.org/obo/HP_0001945 |
| T5 | 570-603 | Phenotype | denotes | elevated C-reactive protein level | http://purl.obolibrary.org/obo/HP_0011227 |
| T6 | 652-657 | Phenotype | denotes | Fever | http://purl.obolibrary.org/obo/HP_0001945 |
| T7 | 1112-1121 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
| T8 | 1213-1222 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
| T9 | 1522-1527 | Phenotype | denotes | fever | http://purl.obolibrary.org/obo/HP_0001945 |
| T10 | 1592-1597 | Phenotype | denotes | Fever | http://purl.obolibrary.org/obo/HP_0001945 |
| T11 | 1826-1831 | Phenotype | denotes | fever | http://purl.obolibrary.org/obo/HP_0001945 |
| T12 | 1924-1944 | Phenotype | denotes | difficulty breathing | http://purl.obolibrary.org/obo/HP_0002098 |
| T13 | 1949-1954 | Phenotype | denotes | cough | http://purl.obolibrary.org/obo/HP_0012735 |
| T14 | 1974-1984 | Phenotype | denotes | runny nose | http://purl.obolibrary.org/obo/HP_0031417 |
| T15 | 2023-2039 | Phenotype | denotes | nausea, vomiting | http://purl.obolibrary.org/obo/HP_0002017 |
| T16 | 2045-2053 | Phenotype | denotes | diarrhea | http://purl.obolibrary.org/obo/HP_0002014 |
| T17 | 2222-2255 | Phenotype | denotes | elevated C-reactive protein level | http://purl.obolibrary.org/obo/HP_0011227 |
| T18 | 2285-2294 | Phenotype | denotes | emphysema | http://purl.obolibrary.org/obo/HP_0002097 |
| T19 | 2402-2411 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
| T20 | 2502-2511 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T8 | 1055-1063 | http://purl.obolibrary.org/obo/GO_0007612 | denotes | learning |
| T9 | 1935-1944 | http://purl.obolibrary.org/obo/GO_0007585 | denotes | breathing |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T16 | 0-11 | Sentence | denotes | CASE REPORT |
| T17 | 13-19 | Sentence | denotes | Case 1 |
| T18 | 20-139 | Sentence | denotes | 10-month-old boy presented with fever for 3 hours and was admitted to the Fever Clinic of the Beijing Haidian Hospital. |
| T19 | 140-206 | Sentence | denotes | His parents and sister were confirmed with COVID-19 2 days before. |
| T20 | 207-304 | Sentence | denotes | They contracted it after having dinner with a family friend who had recently returned from Wuhan. |
| T21 | 305-409 | Sentence | denotes | Physical examination showed fever with a peak body temperature of 38℃ that returned to normal by itself. |
| T22 | 410-614 | Sentence | denotes | Laboratory examination showed normal leukocyte (9.32 × 109/L) and neutrophil (1.93 × 109/L) counts, increased differential count of lymphocytes (68.8%), and an elevated C-reactive protein level (11 mg/L). |
| T23 | 615-772 | Sentence | denotes | The patient had been admitted to the Fever Clinic 2 weeks before because of influenza A infection as evidenced by a weakly positive nucleic acid test result. |
| T24 | 773-884 | Sentence | denotes | Subsequently, the patient underwent isolated medical observation before his family was diagnosed with COVID-19. |
| T25 | 885-1047 | Sentence | denotes | During the medical observation, the nucleic acid test presented weakly positive for influenza A again, and CT showed diffuse ground-glass opacities in both lungs. |
| T26 | 1048-1296 | Sentence | denotes | A deep learning (DL)-based computer-aided diagnostic system for pneumonia, which was trained with CT scans of patients with COVID-19, suggested this patient to have pneumonia, with the lesion volume accounting for 13.3% of the whole lungs (Fig. 1). |
| T27 | 1297-1383 | Sentence | denotes | Later, throat swab specimens from the patient were tested with rRT-PCR for SARS-CoV-2. |
| T28 | 1384-1480 | Sentence | denotes | After two consecutive negative results, a third SARS-CoV-2 rRT-PCR test confirmed the infection. |
| T29 | 1482-1488 | Sentence | denotes | Case 2 |
| T30 | 1489-1562 | Sentence | denotes | A 36-year-old man presented with fever for 5 days (peak body temperature: |
| T31 | 1563-1637 | Sentence | denotes | 40℃) and was admitted to the Fever Clinic of the Beijing Haidian Hospital. |
| T32 | 1638-1797 | Sentence | denotes | The patient had no direct contact history with patients with COVID-19 or people from the Hubei province, but a recent travel history to Chongqing was reported. |
| T33 | 1798-1865 | Sentence | denotes | Physical examination showed fever with a body temperature of 38.5℃. |
| T34 | 1866-1998 | Sentence | denotes | Respiratory symptoms at admission included dry throat and difficulty breathing; no cough, sputum, or stuffy/runny nose was observed. |
| T35 | 1999-2054 | Sentence | denotes | Other symptoms included nausea, vomiting, and diarrhea. |
| T36 | 2055-2268 | Sentence | denotes | Laboratory examination revealed increased leukocyte (13.69 × 109/L) and neutrophil (10.42 × 109/L) counts, decreased differential count of lymphocytes (12.6%), and an elevated C-reactive protein level (155 mg/mL). |
| T37 | 2269-2412 | Sentence | denotes | Chest CT showed emphysema in both upper lungs and diffuse ground-glass opacities in the right lower lobe, highly suggestive of viral pneumonia. |
| T38 | 2413-2583 | Sentence | denotes | In addition, the DL-based computer-aided diagnostic system also indicated a high risk of pneumonia with the infected area accounting for 8.9% of the whole lungs (Fig. 2). |
| T39 | 2584-2667 | Sentence | denotes | Subsequently, throat swab specimens were promptly collected for SARS-CoV-2 rRT-PCR. |
| T40 | 2668-2740 | Sentence | denotes | A negative result for SARS-CoV-2 was observed in the first rRT-PCR test. |
| T41 | 2741-2859 | Sentence | denotes | A second consecutive SARS-CoV-2 rRT-PCR test was conducted immediately thereafter, and a positive result was obtained. |
| T42 | 2860-2947 | Sentence | denotes | The patient was further confirmed with COVID-19 with additional positive rRT-PCR tests. |