
PMC:7082661
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
1 | 88-135 | Species | denotes | Severe Acute Respiratory Syndrome Coronavirus 2 | Tax:2697049 |
8 | 232-254 | Species | denotes | 2019 novel coronavirus | Tax:2697049 |
9 | 271-318 | Species | denotes | severe acute respiratory syndrome coronavirus 2 | Tax:2697049 |
10 | 320-330 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
11 | 833-843 | Species | denotes | SARS-COV-2 | Tax:2697049 |
12 | 472-481 | Disease | denotes | infection | MESH:D007239 |
13 | 816-827 | Disease | denotes | Coinfection | MESH:D060085 |
25 | 1011-1028 | Species | denotes | novel coronavirus | Tax:2697049 |
26 | 1094-1141 | Species | denotes | severe acute respiratory syndrome coronavirus 2 | Tax:2697049 |
27 | 1143-1153 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
28 | 1162-1173 | Species | denotes | Coronavirus | Tax:11118 |
29 | 1330-1347 | Species | denotes | novel coronavirus | Tax:2697049 |
30 | 1581-1591 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
31 | 2084-2091 | Species | denotes | patient | Tax:9606 |
32 | 927-942 | Disease | denotes | 2019, pneumonia | MESH:C000657245 |
33 | 1362-1386 | Disease | denotes | coronavirus disease 2019 | MESH:C000657245 |
34 | 1388-1396 | Disease | denotes | COVID-19 | MESH:C000657245 |
35 | 1653-1662 | Disease | denotes | infection | MESH:D007239 |
42 | 2718-2736 | Gene | denotes | C-reactive protein | Gene:1401 |
43 | 2172-2175 | Species | denotes | boy | Tax:9606 |
44 | 2191-2196 | Disease | denotes | fever | MESH:D005334 |
45 | 2233-2238 | Disease | denotes | Fever | MESH:D005334 |
46 | 2322-2330 | Disease | denotes | COVID-19 | MESH:C000657245 |
47 | 2472-2477 | Disease | denotes | fever | MESH:D005334 |
62 | 2758-2765 | Species | denotes | patient | Tax:9606 |
63 | 2930-2937 | Species | denotes | patient | Tax:9606 |
64 | 3297-3305 | Species | denotes | patients | Tax:9606 |
65 | 3336-3343 | Species | denotes | patient | Tax:9606 |
66 | 3474-3481 | Species | denotes | patient | Tax:9606 |
67 | 3511-3521 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
68 | 3571-3581 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
69 | 2791-2796 | Disease | denotes | Fever | MESH:D005334 |
70 | 2840-2851 | Disease | denotes | A infection | MESH:D007239 |
71 | 3014-3022 | Disease | denotes | COVID-19 | MESH:C000657245 |
72 | 3251-3260 | Disease | denotes | pneumonia | MESH:D011014 |
73 | 3311-3319 | Disease | denotes | COVID-19 | MESH:C000657245 |
74 | 3352-3361 | Disease | denotes | pneumonia | MESH:D011014 |
75 | 3609-3618 | Disease | denotes | infection | MESH:D007239 |
90 | 4370-4388 | Gene | denotes | C-reactive protein | Gene:1401 |
91 | 3781-3788 | Species | denotes | patient | Tax:9606 |
92 | 3824-3832 | Species | denotes | patients | Tax:9606 |
93 | 3850-3856 | Species | denotes | people | Tax:9606 |
94 | 3661-3666 | Disease | denotes | fever | MESH:D005334 |
95 | 3731-3736 | Disease | denotes | Fever | MESH:D005334 |
96 | 3838-3846 | Disease | denotes | COVID-19 | MESH:C000657245 |
97 | 3965-3970 | Disease | denotes | fever | MESH:D005334 |
98 | 4005-4025 | Disease | denotes | Respiratory symptoms | MESH:D012818 |
99 | 4048-4058 | Disease | denotes | dry throat | MESH:D010608 |
100 | 4088-4093 | Disease | denotes | cough | MESH:D003371 |
101 | 4162-4168 | Disease | denotes | nausea | MESH:D009325 |
102 | 4170-4178 | Disease | denotes | vomiting | MESH:D014839 |
103 | 4184-4192 | Disease | denotes | diarrhea | MESH:D003967 |
113 | 4787-4797 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
114 | 4829-4839 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
115 | 4901-4911 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
116 | 5003-5010 | Species | denotes | patient | Tax:9606 |
117 | 4424-4433 | Disease | denotes | emphysema | MESH:D004646 |
118 | 4535-4550 | Disease | denotes | viral pneumonia | |
119 | 4641-4650 | Disease | denotes | pneumonia | MESH:D011014 |
120 | 4660-4668 | Disease | denotes | infected | MESH:D007239 |
121 | 5038-5046 | Disease | denotes | COVID-19 | MESH:C000657245 |
126 | 5181-5191 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
127 | 5168-5177 | Disease | denotes | infection | MESH:D007239 |
128 | 5638-5647 | Disease | denotes | infection | MESH:D007239 |
129 | 5729-5740 | Disease | denotes | coinfection | MESH:D060085 |
134 | 6410-6418 | Species | denotes | patients | Tax:9606 |
135 | 6084-6092 | Disease | denotes | COVID-19 | MESH:C000657245 |
136 | 6424-6432 | Disease | denotes | COVID-19 | MESH:C000657245 |
137 | 6571-6591 | Disease | denotes | SARS-CoV-2 infection | MESH:C000657245 |
149 | 6767-6775 | Species | denotes | patients | Tax:9606 |
150 | 7901-7909 | Species | denotes | patients | Tax:9606 |
151 | 6781-6789 | Disease | denotes | COVID-19 | MESH:C000657245 |
152 | 6968-6976 | Disease | denotes | COVID-19 | MESH:C000657245 |
153 | 7198-7207 | Disease | denotes | pneumonia | MESH:D011014 |
154 | 7339-7347 | Disease | denotes | COVID-19 | MESH:C000657245 |
155 | 7794-7803 | Disease | denotes | Pneumonia | MESH:D011014 |
156 | 7838-7847 | Disease | denotes | pneumonia | MESH:D011014 |
157 | 7932-7940 | Disease | denotes | COVID-19 | MESH:C000657245 |
158 | 8130-8138 | Disease | denotes | COVID-19 | MESH:C000657245 |
159 | 8255-8263 | Disease | denotes | COVID-19 | MESH:C000657245 |
171 | 8479-8497 | Gene | denotes | C-reactive protein | Gene:1401 |
172 | 8687-8705 | Gene | denotes | C-reactive protein | Gene:1401 |
173 | 8370-8378 | Species | denotes | patients | Tax:9606 |
174 | 8380-8387 | Species | denotes | Patient | Tax:9606 |
175 | 8419-8429 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
176 | 8583-8590 | Species | denotes | patient | Tax:9606 |
177 | 8402-8410 | Disease | denotes | infected | MESH:D007239 |
178 | 8549-8557 | Disease | denotes | COVID-19 | MESH:C000657245 |
179 | 8802-8811 | Disease | denotes | infection | MESH:D007239 |
180 | 8830-8850 | Disease | denotes | SARS-CoV-2 infection | MESH:C000657245 |
181 | 8860-8871 | Disease | denotes | coinfection | MESH:D060085 |
185 | 9022-9042 | Disease | denotes | SARS-CoV-2 infection | MESH:C000657245 |
186 | 9156-9164 | Disease | denotes | COVID-19 | MESH:C000657245 |
187 | 9255-9264 | Disease | denotes | infection | MESH:D007239 |
201 | 9424-9431 | Species | denotes | patient | Tax:9606 |
205 | 9545-9552 | Species | denotes | patient | Tax:9606 |
206 | 9615-9631 | Disease | denotes | upper lung lobes | MESH:D012141 |
207 | 9814-9823 | Disease | denotes | pneumonia | MESH:D011014 |
209 | 10128-10135 | Species | denotes | patient | Tax:9606 |
211 | 10458-10467 | Disease | denotes | pneumonia | MESH:D011014 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T1 | 2490-2494 | Body_part | denotes | body | http://purl.org/sig/ont/fma/fma256135 |
T2 | 2586-2595 | Body_part | denotes | leukocyte | http://purl.org/sig/ont/fma/fma62852 |
T3 | 2615-2625 | Body_part | denotes | neutrophil | http://purl.org/sig/ont/fma/fma62860 |
T4 | 2681-2692 | Body_part | denotes | lymphocytes | http://purl.org/sig/ont/fma/fma62863 |
T5 | 2729-2736 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T6 | 3180-3185 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
T7 | 3420-3425 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
T8 | 3443-3449 | Body_part | denotes | throat | http://purl.org/sig/ont/fma/fma228738 |
T9 | 3684-3688 | Body_part | denotes | body | http://purl.org/sig/ont/fma/fma256135 |
T10 | 3978-3982 | Body_part | denotes | body | http://purl.org/sig/ont/fma/fma256135 |
T11 | 4052-4058 | Body_part | denotes | throat | http://purl.org/sig/ont/fma/fma228738 |
T12 | 4095-4101 | Body_part | denotes | sputum | http://purl.org/sig/ont/fma/fma312401 |
T13 | 4119-4123 | Body_part | denotes | nose | http://purl.org/sig/ont/fma/fma46472 |
T14 | 4236-4245 | Body_part | denotes | leukocyte | http://purl.org/sig/ont/fma/fma62852 |
T15 | 4266-4276 | Body_part | denotes | neutrophil | http://purl.org/sig/ont/fma/fma62860 |
T16 | 4333-4344 | Body_part | denotes | lymphocytes | http://purl.org/sig/ont/fma/fma62863 |
T17 | 4381-4388 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T18 | 4408-4413 | Body_part | denotes | Chest | http://purl.org/sig/ont/fma/fma9576 |
T19 | 4448-4453 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
T20 | 4496-4512 | Body_part | denotes | right lower lobe | http://purl.org/sig/ont/fma/fma7337 |
T21 | 4707-4712 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
T22 | 4737-4743 | Body_part | denotes | throat | http://purl.org/sig/ont/fma/fma228738 |
T23 | 6389-6394 | Body_part | denotes | chest | http://purl.org/sig/ont/fma/fma9576 |
T24 | 6683-6688 | Body_part | denotes | chest | http://purl.org/sig/ont/fma/fma9576 |
T25 | 6805-6810 | Body_part | denotes | chest | http://purl.org/sig/ont/fma/fma9576 |
T26 | 6925-6930 | Body_part | denotes | chest | http://purl.org/sig/ont/fma/fma9576 |
T27 | 7211-7216 | Body_part | denotes | chest | http://purl.org/sig/ont/fma/fma9576 |
T28 | 8454-8465 | Body_part | denotes | lymphocytes | http://purl.org/sig/ont/fma/fma62863 |
T29 | 8490-8497 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T30 | 8662-8673 | Body_part | denotes | lymphocytes | http://purl.org/sig/ont/fma/fma62863 |
T31 | 8698-8705 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T32 | 9392-9397 | Body_part | denotes | Chest | http://purl.org/sig/ont/fma/fma9576 |
T33 | 9621-9625 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T34 | 9690-9699 | Body_part | denotes | left lung | http://purl.org/sig/ont/fma/fma7310 |
T35 | 9881-9885 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T36 | 9929-9934 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
T37 | 9936-9952 | Body_part | denotes | right upper lobe | http://purl.org/sig/ont/fma/fma7333 |
T38 | 9954-9971 | Body_part | denotes | right middle lobe | http://purl.org/sig/ont/fma/fma7383 |
T39 | 9973-9989 | Body_part | denotes | right lower lobe | http://purl.org/sig/ont/fma/fma7337 |
T40 | 9991-10006 | Body_part | denotes | left upper lobe | http://purl.org/sig/ont/fma/fma7370 |
T41 | 10012-10027 | Body_part | denotes | left lower lobe | http://purl.org/sig/ont/fma/fma7371 |
T42 | 10109-10114 | Body_part | denotes | Chest | http://purl.org/sig/ont/fma/fma9576 |
T43 | 10261-10277 | Body_part | denotes | right lower lobe | http://purl.org/sig/ont/fma/fma7337 |
T44 | 10336-10360 | Body_part | denotes | lower lobe of right lung | http://purl.org/sig/ont/fma/fma7337 |
T45 | 10525-10529 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T46 | 10573-10578 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
T47 | 10580-10596 | Body_part | denotes | right upper lobe | http://purl.org/sig/ont/fma/fma7333 |
T48 | 10598-10615 | Body_part | denotes | right middle lobe | http://purl.org/sig/ont/fma/fma7383 |
T49 | 10617-10633 | Body_part | denotes | right lower lobe | http://purl.org/sig/ont/fma/fma7337 |
T50 | 10635-10650 | Body_part | denotes | left upper lobe | http://purl.org/sig/ont/fma/fma7370 |
T51 | 10656-10671 | Body_part | denotes | left lower lobe | http://purl.org/sig/ont/fma/fma7371 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 3443-3449 | Body_part | denotes | throat | http://purl.obolibrary.org/obo/UBERON_0000341 |
T2 | 4052-4058 | Body_part | denotes | throat | http://purl.obolibrary.org/obo/UBERON_0000341 |
T3 | 4095-4101 | Body_part | denotes | sputum | http://purl.obolibrary.org/obo/UBERON_0007311 |
T4 | 4119-4123 | Body_part | denotes | nose | http://purl.obolibrary.org/obo/UBERON_0000004 |
T5 | 4408-4413 | Body_part | denotes | Chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
T6 | 4508-4512 | Body_part | denotes | lobe | http://purl.obolibrary.org/obo/UBERON_3010752 |
T7 | 4737-4743 | Body_part | denotes | throat | http://purl.obolibrary.org/obo/UBERON_0000341 |
T8 | 6389-6394 | Body_part | denotes | chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
T9 | 6683-6688 | Body_part | denotes | chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
T10 | 6805-6810 | Body_part | denotes | chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
T11 | 6925-6930 | Body_part | denotes | chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
T12 | 7211-7216 | Body_part | denotes | chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
T13 | 9392-9397 | Body_part | denotes | Chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
T14 | 9621-9625 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T15 | 9690-9699 | Body_part | denotes | left lung | http://purl.obolibrary.org/obo/UBERON_0002168 |
T16 | 9695-9699 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T17 | 9881-9885 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T18 | 9948-9952 | Body_part | denotes | lobe | http://purl.obolibrary.org/obo/UBERON_3010752 |
T19 | 9967-9971 | Body_part | denotes | lobe | http://purl.obolibrary.org/obo/UBERON_3010752 |
T20 | 9985-9989 | Body_part | denotes | lobe | http://purl.obolibrary.org/obo/UBERON_3010752 |
T21 | 10002-10006 | Body_part | denotes | lobe | http://purl.obolibrary.org/obo/UBERON_3010752 |
T22 | 10023-10027 | Body_part | denotes | lobe | http://purl.obolibrary.org/obo/UBERON_3010752 |
T23 | 10109-10114 | Body_part | denotes | Chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
T24 | 10273-10277 | Body_part | denotes | lobe | http://purl.obolibrary.org/obo/UBERON_3010752 |
T25 | 10336-10360 | Body_part | denotes | lower lobe of right lung | http://purl.obolibrary.org/obo/UBERON_0002171 |
T26 | 10342-10346 | Body_part | denotes | lobe | http://purl.obolibrary.org/obo/UBERON_3010752 |
T27 | 10350-10360 | Body_part | denotes | right lung | http://purl.obolibrary.org/obo/UBERON_0002167 |
T28 | 10356-10360 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T29 | 10525-10529 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T30 | 10592-10596 | Body_part | denotes | lobe | http://purl.obolibrary.org/obo/UBERON_3010752 |
T31 | 10611-10615 | Body_part | denotes | lobe | http://purl.obolibrary.org/obo/UBERON_3010752 |
T32 | 10629-10633 | Body_part | denotes | lobe | http://purl.obolibrary.org/obo/UBERON_3010752 |
T33 | 10646-10650 | Body_part | denotes | lobe | http://purl.obolibrary.org/obo/UBERON_3010752 |
T34 | 10667-10671 | Body_part | denotes | lobe | http://purl.obolibrary.org/obo/UBERON_3010752 |
LitCovid_AGAC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
p26083s15 | 8444-8453 | NegReg | denotes | decreased |
p26083s16 | 8454-8465 | CPA | denotes | lymphocytes |
p26083s18 | 8470-8478 | PosReg | denotes | elevated |
p26083s19 | 8479-8480 | MPA | denotes | C |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 88-135 | Disease | denotes | Severe Acute Respiratory Syndrome Coronavirus 2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T2 | 271-318 | Disease | denotes | severe acute respiratory syndrome coronavirus 2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T3 | 271-304 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
T4 | 320-328 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T5 | 472-481 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T6 | 833-837 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T7 | 933-942 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
T8 | 1094-1141 | Disease | denotes | severe acute respiratory syndrome coronavirus 2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T9 | 1094-1127 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
T10 | 1143-1151 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T11 | 1362-1386 | Disease | denotes | coronavirus disease 2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T12 | 1388-1396 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T13 | 1581-1589 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T14 | 1653-1662 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T15 | 2322-2330 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T16 | 2830-2839 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
T17 | 2842-2851 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T18 | 3014-3022 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T19 | 3108-3117 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
T20 | 3251-3260 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
T21 | 3311-3319 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T22 | 3352-3361 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
T23 | 3511-3519 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T24 | 3571-3579 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T25 | 3609-3618 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T26 | 3838-3846 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T27 | 4113-4123 | Disease | denotes | runny nose | http://purl.obolibrary.org/obo/MONDO_0003014 |
T28 | 4184-4192 | Disease | denotes | diarrhea | http://purl.obolibrary.org/obo/MONDO_0001673 |
T29 | 4424-4433 | Disease | denotes | emphysema | http://purl.obolibrary.org/obo/MONDO_0004849 |
T30 | 4535-4550 | Disease | denotes | viral pneumonia | http://purl.obolibrary.org/obo/MONDO_0006012 |
T31 | 4541-4550 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
T32 | 4641-4650 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
T33 | 4787-4795 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T34 | 4829-4837 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T35 | 4901-4909 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T36 | 5038-5046 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T37 | 5168-5177 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T38 | 5181-5189 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T39 | 5638-5647 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T40 | 6084-6092 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T41 | 6424-6432 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T42 | 6571-6579 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T43 | 6582-6591 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T44 | 6781-6789 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T45 | 6968-6976 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T46 | 7198-7207 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
T47 | 7339-7347 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T48 | 7794-7803 | Disease | denotes | Pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
T49 | 7838-7847 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
T50 | 7932-7940 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T51 | 8130-8138 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T52 | 8255-8263 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T53 | 8419-8427 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T54 | 8549-8557 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T55 | 8621-8630 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
T56 | 8802-8811 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T57 | 8830-8838 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T58 | 8841-8850 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T59 | 9022-9030 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T60 | 9033-9042 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T61 | 9156-9164 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T62 | 9255-9264 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T63 | 9814-9823 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
T64 | 10458-10467 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 390-394 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
T2 | 854-861 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
T3 | 862-865 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T4 | 1009-1010 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T5 | 1232-1239 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | Viruses |
T6 | 1418-1430 | http://purl.obolibrary.org/obo/OBI_0000245 | denotes | Organization |
T7 | 1454-1457 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T8 | 1550-1554 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
T9 | 1888-1889 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T10 | 2390-2391 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T11 | 2483-2484 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T12 | 2744-2746 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
T13 | 2840-2841 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T14 | 2868-2869 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T15 | 2899-2903 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
T16 | 3073-3077 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
T17 | 3118-3119 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T18 | 3180-3185 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
T19 | 3187-3188 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T20 | 3420-3425 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
T21 | 3487-3493 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tested |
T22 | 3563-3564 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T23 | 3590-3594 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
T24 | 3628-3629 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T25 | 3630-3632 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 36 |
T26 | 3886-3887 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T27 | 3976-3977 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T28 | 4119-4123 | http://www.ebi.ac.uk/efo/EFO_0000828 | denotes | nose |
T29 | 4408-4413 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | Chest |
T30 | 4448-4453 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
T31 | 4626-4627 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T32 | 4707-4712 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
T33 | 4807-4808 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T34 | 4874-4878 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
T35 | 4880-4881 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T36 | 4920-4928 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test was |
T37 | 4967-4968 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T38 | 5080-5085 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tests |
T39 | 5113-5118 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tests |
T40 | 5296-5300 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
T41 | 5307-5308 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T42 | 5480-5481 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T43 | 5752-5759 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
T44 | 5788-5792 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
T45 | 5997-6000 | http://purl.obolibrary.org/obo/CLO_0050884 | denotes | ten |
T46 | 6037-6041 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
T47 | 6389-6394 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | chest |
T48 | 6644-6651 | http://purl.obolibrary.org/obo/CLO_0009985 | denotes | focused |
T49 | 6683-6688 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | chest |
T50 | 6805-6810 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | chest |
T51 | 6913-6915 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 34 |
T52 | 6925-6930 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | chest |
T53 | 7079-7080 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T54 | 7111-7112 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T55 | 7211-7216 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | chest |
T56 | 7354-7355 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T57 | 7548-7549 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T58 | 7736-7737 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T59 | 8631-8632 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T60 | 8765-8766 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T61 | 8790-8791 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T62 | 8883-8890 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
T63 | 9392-9397 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | Chest |
T64 | 9443-9444 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T65 | 9621-9625 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T66 | 9621-9625 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T67 | 9633-9634 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
T68 | 9690-9699 | http://purl.obolibrary.org/obo/UBERON_0002168 | denotes | left lung |
T69 | 9881-9885 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T70 | 9881-9885 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T71 | 9929-9934 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
T72 | 10109-10114 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | Chest |
T73 | 10147-10148 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T74 | 10279-10280 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
T75 | 10350-10360 | http://purl.obolibrary.org/obo/UBERON_0002167 | denotes | right lung |
T76 | 10525-10529 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T77 | 10525-10529 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T78 | 10573-10578 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T1 | 377-389 | Chemical | denotes | nucleic acid | http://purl.obolibrary.org/obo/CHEBI_33696 |
T2 | 385-389 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T3 | 431-435 | Chemical | denotes | gold | http://purl.obolibrary.org/obo/CHEBI_29287|http://purl.obolibrary.org/obo/CHEBI_30050 |
T5 | 1537-1549 | Chemical | denotes | nucleic acid | http://purl.obolibrary.org/obo/CHEBI_33696 |
T6 | 1545-1549 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T7 | 1612-1616 | Chemical | denotes | gold | http://purl.obolibrary.org/obo/CHEBI_29287|http://purl.obolibrary.org/obo/CHEBI_30050 |
T9 | 2729-2736 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T10 | 2886-2898 | Chemical | denotes | nucleic acid | http://purl.obolibrary.org/obo/CHEBI_33696 |
T11 | 2894-2898 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T12 | 3060-3072 | Chemical | denotes | nucleic acid | http://purl.obolibrary.org/obo/CHEBI_33696 |
T13 | 3068-3072 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T14 | 3204-3206 | Chemical | denotes | DL | http://purl.obolibrary.org/obo/CHEBI_68596 |
T15 | 4381-4388 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T16 | 4569-4571 | Chemical | denotes | DL | http://purl.obolibrary.org/obo/CHEBI_68596 |
T17 | 5132-5136 | Chemical | denotes | gold | http://purl.obolibrary.org/obo/CHEBI_29287|http://purl.obolibrary.org/obo/CHEBI_30050 |
T19 | 7738-7740 | Chemical | denotes | DL | http://purl.obolibrary.org/obo/CHEBI_68596 |
T20 | 8186-8188 | Chemical | denotes | DL | http://purl.obolibrary.org/obo/CHEBI_68596 |
T21 | 8490-8497 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T22 | 8698-8705 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T23 | 8777-8786 | Chemical | denotes | indicator | http://purl.obolibrary.org/obo/CHEBI_47867 |
T24 | 9654-9656 | Chemical | denotes | DL | http://purl.obolibrary.org/obo/CHEBI_68596 |
T25 | 10082-10084 | Chemical | denotes | DL | http://purl.obolibrary.org/obo/CHEBI_68596 |
T26 | 10300-10302 | Chemical | denotes | DL | http://purl.obolibrary.org/obo/CHEBI_68596 |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T1 | 933-942 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
T2 | 2191-2196 | Phenotype | denotes | fever | http://purl.obolibrary.org/obo/HP_0001945 |
T3 | 2233-2238 | Phenotype | denotes | Fever | http://purl.obolibrary.org/obo/HP_0001945 |
T4 | 2472-2477 | Phenotype | denotes | fever | http://purl.obolibrary.org/obo/HP_0001945 |
T5 | 2709-2742 | Phenotype | denotes | elevated C-reactive protein level | http://purl.obolibrary.org/obo/HP_0011227 |
T6 | 2791-2796 | Phenotype | denotes | Fever | http://purl.obolibrary.org/obo/HP_0001945 |
T7 | 3251-3260 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
T8 | 3352-3361 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
T9 | 3661-3666 | Phenotype | denotes | fever | http://purl.obolibrary.org/obo/HP_0001945 |
T10 | 3731-3736 | Phenotype | denotes | Fever | http://purl.obolibrary.org/obo/HP_0001945 |
T11 | 3965-3970 | Phenotype | denotes | fever | http://purl.obolibrary.org/obo/HP_0001945 |
T12 | 4063-4083 | Phenotype | denotes | difficulty breathing | http://purl.obolibrary.org/obo/HP_0002098 |
T13 | 4088-4093 | Phenotype | denotes | cough | http://purl.obolibrary.org/obo/HP_0012735 |
T14 | 4113-4123 | Phenotype | denotes | runny nose | http://purl.obolibrary.org/obo/HP_0031417 |
T15 | 4162-4178 | Phenotype | denotes | nausea, vomiting | http://purl.obolibrary.org/obo/HP_0002017 |
T16 | 4184-4192 | Phenotype | denotes | diarrhea | http://purl.obolibrary.org/obo/HP_0002014 |
T17 | 4361-4394 | Phenotype | denotes | elevated C-reactive protein level | http://purl.obolibrary.org/obo/HP_0011227 |
T18 | 4424-4433 | Phenotype | denotes | emphysema | http://purl.obolibrary.org/obo/HP_0002097 |
T19 | 4541-4550 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
T20 | 4641-4650 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
T21 | 7198-7207 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
T22 | 7794-7803 | Phenotype | denotes | Pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
T23 | 7838-7847 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
T24 | 9814-9823 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
T25 | 10458-10467 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 44-57 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | Transcriptase |
T2 | 44-57 | http://purl.obolibrary.org/obo/GO_0003899 | denotes | Transcriptase |
T3 | 150-158 | http://purl.obolibrary.org/obo/GO_0007612 | denotes | Learning |
T4 | 568-581 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | transcriptase |
T5 | 568-581 | http://purl.obolibrary.org/obo/GO_0003899 | denotes | transcriptase |
T6 | 1728-1741 | http://purl.obolibrary.org/obo/GO_0003968 | denotes | transcriptase |
T7 | 1728-1741 | http://purl.obolibrary.org/obo/GO_0003899 | denotes | transcriptase |
T8 | 3194-3202 | http://purl.obolibrary.org/obo/GO_0007612 | denotes | learning |
T9 | 4074-4083 | http://purl.obolibrary.org/obo/GO_0007585 | denotes | breathing |
T10 | 8063-8075 | http://purl.obolibrary.org/obo/GO_0035282 | denotes | segmentation |
T11 | 9496-9505 | http://purl.obolibrary.org/obo/GO_0007585 | denotes | breathing |
T12 | 9663-9675 | http://purl.obolibrary.org/obo/GO_0035282 | denotes | segmentation |
T13 | 10092-10100 | http://purl.obolibrary.org/obo/GO_0007612 | denotes | learning |
T14 | 10309-10321 | http://purl.obolibrary.org/obo/GO_0035282 | denotes | segmentation |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-136 | Sentence | denotes | False-Negative Results of Real-Time Reverse-Transcriptase Polymerase Chain Reaction for Severe Acute Respiratory Syndrome Coronavirus 2: |
T2 | 137-205 | Sentence | denotes | Role of Deep-Learning-Based CT Diagnosis and Insights from Two Cases |
T3 | 207-215 | Sentence | denotes | Abstract |
T4 | 216-372 | Sentence | denotes | The epidemic of 2019 novel coronavirus, later named as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is still gradually spreading worldwide. |
T5 | 373-618 | Sentence | denotes | The nucleic acid test or genetic sequencing serves as the gold standard method for confirmation of infection, yet several recent studies have reported false-negative results of real-time reverse-transcriptase polymerase chain reaction (rRT-PCR). |
T6 | 619-815 | Sentence | denotes | Here, we report two representative false-negative cases and discuss the supplementary role of clinical data with rRT-PCR, including laboratory examination results and computed tomography features. |
T7 | 816-889 | Sentence | denotes | Coinfection with SARS-COV-2 and other viruses has been discussed as well. |
T8 | 891-903 | Sentence | denotes | INTRODUCTION |
T9 | 904-994 | Sentence | denotes | At the end of December 2019, pneumonia of unknown causes broke out in Wuhan, Hubei, China. |
T10 | 995-1305 | Sentence | denotes | Subsequently, a novel coronavirus was found to be the causative pathogen, which was later named as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by the Coronavirus Study Group of the International Committee on Taxonomy of Viruses based on its phylogeny, taxonomy, and established practices (12). |
T11 | 1306-1431 | Sentence | denotes | Diseases caused by this novel coronavirus were named as coronavirus disease 2019 (COVID-19) by the World Health Organization. |
T12 | 1432-1532 | Sentence | denotes | To date, the epidemic has gradually spread to over 30 provinces of China and 26 countries worldwide. |
T13 | 1533-1663 | Sentence | denotes | The nucleic acid test or genetic sequencing for SARS-CoV-2 was regarded as the gold standard method for confirmation of infection. |
T14 | 1664-1935 | Sentence | denotes | Here, we report two false negative results of real-time reverse-transcriptase polymerase chain reaction (rRT-PCR) and discuss complementary approaches, such as computed tomography (CT) in combination with rRT-PCR to achieve a more reliable diagnosis in clinical practice. |
T15 | 1936-2137 | Sentence | denotes | This study was approved by the Institutional Review Board of the Beijing Haidian Hospital, and the requirement of informed consent was waived since patient information was anonymized to ensure privacy. |
T16 | 2139-2150 | Sentence | denotes | CASE REPORT |
T17 | 2152-2158 | Sentence | denotes | Case 1 |
T18 | 2159-2278 | Sentence | denotes | 10-month-old boy presented with fever for 3 hours and was admitted to the Fever Clinic of the Beijing Haidian Hospital. |
T19 | 2279-2345 | Sentence | denotes | His parents and sister were confirmed with COVID-19 2 days before. |
T20 | 2346-2443 | Sentence | denotes | They contracted it after having dinner with a family friend who had recently returned from Wuhan. |
T21 | 2444-2548 | Sentence | denotes | Physical examination showed fever with a peak body temperature of 38℃ that returned to normal by itself. |
T22 | 2549-2753 | Sentence | denotes | Laboratory examination showed normal leukocyte (9.32 × 109/L) and neutrophil (1.93 × 109/L) counts, increased differential count of lymphocytes (68.8%), and an elevated C-reactive protein level (11 mg/L). |
T23 | 2754-2911 | Sentence | denotes | The patient had been admitted to the Fever Clinic 2 weeks before because of influenza A infection as evidenced by a weakly positive nucleic acid test result. |
T24 | 2912-3023 | Sentence | denotes | Subsequently, the patient underwent isolated medical observation before his family was diagnosed with COVID-19. |
T25 | 3024-3186 | Sentence | denotes | During the medical observation, the nucleic acid test presented weakly positive for influenza A again, and CT showed diffuse ground-glass opacities in both lungs. |
T26 | 3187-3435 | Sentence | denotes | A deep learning (DL)-based computer-aided diagnostic system for pneumonia, which was trained with CT scans of patients with COVID-19, suggested this patient to have pneumonia, with the lesion volume accounting for 13.3% of the whole lungs (Fig. 1). |
T27 | 3436-3522 | Sentence | denotes | Later, throat swab specimens from the patient were tested with rRT-PCR for SARS-CoV-2. |
T28 | 3523-3619 | Sentence | denotes | After two consecutive negative results, a third SARS-CoV-2 rRT-PCR test confirmed the infection. |
T29 | 3621-3627 | Sentence | denotes | Case 2 |
T30 | 3628-3701 | Sentence | denotes | A 36-year-old man presented with fever for 5 days (peak body temperature: |
T31 | 3702-3776 | Sentence | denotes | 40℃) and was admitted to the Fever Clinic of the Beijing Haidian Hospital. |
T32 | 3777-3936 | Sentence | denotes | The patient had no direct contact history with patients with COVID-19 or people from the Hubei province, but a recent travel history to Chongqing was reported. |
T33 | 3937-4004 | Sentence | denotes | Physical examination showed fever with a body temperature of 38.5℃. |
T34 | 4005-4137 | Sentence | denotes | Respiratory symptoms at admission included dry throat and difficulty breathing; no cough, sputum, or stuffy/runny nose was observed. |
T35 | 4138-4193 | Sentence | denotes | Other symptoms included nausea, vomiting, and diarrhea. |
T36 | 4194-4407 | Sentence | denotes | Laboratory examination revealed increased leukocyte (13.69 × 109/L) and neutrophil (10.42 × 109/L) counts, decreased differential count of lymphocytes (12.6%), and an elevated C-reactive protein level (155 mg/mL). |
T37 | 4408-4551 | Sentence | denotes | Chest CT showed emphysema in both upper lungs and diffuse ground-glass opacities in the right lower lobe, highly suggestive of viral pneumonia. |
T38 | 4552-4722 | Sentence | denotes | In addition, the DL-based computer-aided diagnostic system also indicated a high risk of pneumonia with the infected area accounting for 8.9% of the whole lungs (Fig. 2). |
T39 | 4723-4806 | Sentence | denotes | Subsequently, throat swab specimens were promptly collected for SARS-CoV-2 rRT-PCR. |
T40 | 4807-4879 | Sentence | denotes | A negative result for SARS-CoV-2 was observed in the first rRT-PCR test. |
T41 | 4880-4998 | Sentence | denotes | A second consecutive SARS-CoV-2 rRT-PCR test was conducted immediately thereafter, and a positive result was obtained. |
T42 | 4999-5086 | Sentence | denotes | The patient was further confirmed with COVID-19 with additional positive rRT-PCR tests. |
T43 | 5088-5098 | Sentence | denotes | DISCUSSION |
T44 | 5099-5410 | Sentence | denotes | Since rRT-PCR tests serve as the gold standard method to confirm the infection of SARS-CoV-2, false-negative results could hinder the prevention and control of the epidemic, particularly when this test plays a key reference role in deciding the necessity for continued isolated medical observation or discharge. |
T45 | 5411-5597 | Sentence | denotes | Regarding the underlying reasons for false-negative rRT-PCR results, a previous published study suggested that insufficient viral specimens and laboratory error might be responsible (3). |
T46 | 5598-5851 | Sentence | denotes | We speculated from these two cases that infection routes, disease progression status (specimen collection timing and methods), and coinfection with other viruses might influence the rRT-PCR test accuracy, which should be further studied with more cases. |
T47 | 5852-5911 | Sentence | denotes | False-negative rRT-PCR results were seen in many hospitals. |
T48 | 5912-6155 | Sentence | denotes | By monitoring data collected at our hospital from January 21 to 31, 2020, two out of ten negative cases shown by the rRT-PCR test were finally confirmed to be positive for COVID-19, yielding an approximately 20% false-negative rate of rRT-PCR. |
T49 | 6156-6327 | Sentence | denotes | Although the false-negative estimate would not be accurate until we expand the observational time span and number of monitored cases, the drawback of rRT-PCR was revealed. |
T50 | 6328-6497 | Sentence | denotes | Clinical manifestations, laboratory examination results, and chest CT features of patients with COVID-19 were also of great value in helping the detection and diagnosis. |
T51 | 6498-6592 | Sentence | denotes | Thus, an integrated criterion should be established for the diagnosis of SARS-CoV-2 infection. |
T52 | 6593-6736 | Sentence | denotes | In addition to the epidemiological information, we focused on two aspects of information: chest CT features and laboratory examination results. |
T53 | 6737-6977 | Sentence | denotes | Of note, approximately 96% of patients with COVID-19 presented with chest CT abnormalities, such as multiple bilateral and peripheral ground-glass opacities and consolidation (34), making chest CT features essential in recognizing COVID-19. |
T54 | 6978-7110 | Sentence | denotes | The National Health Commission of China revised the diagnostic criteria in the Hubei province, where a severe epidemic occurred (5). |
T55 | 7111-7251 | Sentence | denotes | A new diagnostic type called “Clinical diagnosis” was set according to the presence of pneumonia on chest CT, regardless of rRT-PCR results. |
T56 | 7252-7348 | Sentence | denotes | To some extent, CT features and rRT-PCR results were complimentary in the diagnosis of COVID-19. |
T57 | 7349-7692 | Sentence | denotes | From a clinical perspective, CT features could be utilized as the first and immediate reference for doctors to screen the highly suspected cases and to take necessary actions while rRT-PCR serves as a confirmation tool, the results of which could be utilized later to decide the subsequent action of continuing isolated treatment or discharge. |
T58 | 7693-8041 | Sentence | denotes | Notably, our hospital was facilitated with a DL-based computer-aided diagnostic system (InferRead CT Pneumonia, Infervision, Beijing, China) for pneumonia, which greatly improved the detection efficiency for patients highly suspected with COVID-19 by alarming the technician within 2 minutes when any suspected cases was found after CT examination. |
T59 | 8042-8154 | Sentence | denotes | The automatic lesion segmentation on CT was also helpful to evaluate the progression of COVID-19 quantitatively. |
T60 | 8155-8288 | Sentence | denotes | With an integrated approach of DL, CT features, and rRT-PCR results, the screening and treatment of COVID-19 would be more effective. |
T61 | 8289-8379 | Sentence | denotes | Furthermore, we observed conflicting laboratory examination results in these two patients. |
T62 | 8380-8565 | Sentence | denotes | Patient in Case 2 was infected only by SARS-CoV-2 and presented decreased lymphocytes and elevated C-reactive protein, consistent with the typical tendency found in the COVID-19 cohort. |
T63 | 8566-8706 | Sentence | denotes | In contrast, the patient in Case 1 was coinfected with influenza A and presented with increased lymphocytes and elevated C-reactive protein. |
T64 | 8707-8952 | Sentence | denotes | The difference in laboratory examination results could be a potential indicator of a different infection status, including SARS-CoV-2 infection alone or coinfection with other viruses, which, however, should be further validated with more cases. |
T65 | 8953-9165 | Sentence | denotes | In conclusion, we reported two false-negative results of rRT-PCR for SARS-CoV-2 infection and mentioned the possible tandem approaches for clinical practices to ensure an early and accurate diagnosis of COVID-19. |
T66 | 9166-9293 | Sentence | denotes | In addition, the potential role of laboratory examination results in differentiating the infection status was revealed as well. |
T67 | 9295-9317 | Sentence | denotes | Conflicts of Interest: |
T68 | 9318-9382 | Sentence | denotes | The authors have no potential conflicts of interest to disclose. |
T69 | 9384-9442 | Sentence | denotes | Fig. 1 Chest CT scans for 10-month-old patient in Case 1. |
T70 | 9443-9445 | Sentence | denotes | A. |
T71 | 9446-9554 | Sentence | denotes | Thin-slice CT scan that shows glimpse of lesions (breathing-induced motion artifacts are heavy for patient). |
T72 | 9555-9632 | Sentence | denotes | CT shows diffuse ill-defined ground-glass opacities in both upper lung lobes. |
T73 | 9633-9635 | Sentence | denotes | B. |
T74 | 9636-9772 | Sentence | denotes | Representative of DL-based segmentation of lesions in left lung that shows overview of automatically calculated abnormality proportions. |
T75 | 9773-9886 | Sentence | denotes | Artificial intelligence alarms suspected pneumonia based on relatively large proportion of abnormalities in lung. |
T76 | 9887-10055 | Sentence | denotes | Detailed abnormality proportions in whole lungs, right upper lobe, right middle lobe, right lower lobe, left upper lobe, and left lower lobe were calculated and listed. |
T77 | 10056-10100 | Sentence | denotes | CT = computed tomography, DL = deep learning |
T78 | 10101-10146 | Sentence | denotes | Fig. 2 Chest CT scans for patient in Case 2. |
T79 | 10147-10149 | Sentence | denotes | A. |
T80 | 10150-10199 | Sentence | denotes | Thin-slice CT scan that shows glimpse of lesions. |
T81 | 10200-10278 | Sentence | denotes | CT shows diffuse ground-glass opacities in dependent area of right lower lobe. |
T82 | 10279-10281 | Sentence | denotes | B. |
T83 | 10282-10416 | Sentence | denotes | Representative of DL-based segmentation of lesions in lower lobe of right lung that shows overview of automatically calculated ratios. |
T84 | 10417-10530 | Sentence | denotes | Artificial intelligence alarms suspected pneumonia based on relatively large proportion of abnormalities in lung. |
T85 | 10531-10699 | Sentence | denotes | Detailed abnormality proportions in whole lungs, right upper lobe, right middle lobe, right lower lobe, left upper lobe, and left lower lobe were calculated and listed. |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32174053-31978945-66079542 | 1301-1303 | 31978945 | denotes | 12 |