PMC:7081066 / 5986-7093
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
170 | 25-30 | Gene | denotes | spike | Gene:43740568 |
171 | 43-52 | Species | denotes | SARS-CoVs | Tax:694009 |
193 | 103-108 | Gene | denotes | spike | Gene:43740568 |
194 | 718-723 | Gene | denotes | spike | Gene:43740568 |
195 | 517-522 | Gene | denotes | spike | Gene:43740568 |
196 | 130-140 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
197 | 149-153 | Species | denotes | CoVs | Tax:11118 |
198 | 155-163 | Species | denotes | SARS-CoV | Tax:694009 |
199 | 277-287 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
200 | 299-302 | Species | denotes | CoV | Tax:11118 |
201 | 366-374 | Species | denotes | SARS-CoV | Tax:694009 |
202 | 390-393 | Species | denotes | CoV | Tax:11118 |
203 | 397-416 | Species | denotes | Rhinolophus affinis | Tax:59477 |
204 | 535-538 | Species | denotes | CoV | Tax:11118 |
205 | 546-556 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
206 | 734-742 | Species | denotes | SARS-CoV | Tax:694009 |
207 | 751-754 | Species | denotes | CoV | Tax:11118 |
208 | 760-779 | Species | denotes | Rhinolophus sinicus | Tax:89399 |
209 | 838-848 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
210 | 928-938 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
211 | 955-958 | Species | denotes | CoV | Tax:11118 |
212 | 964-983 | Species | denotes | Rhinolophus affinis | Tax:59477 |
213 | 1033-1038 | Species | denotes | CoV-2 | Tax:2697049 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T35 | 31-39 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T36 | 109-116 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T37 | 724-732 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T38 | 866-876 | Body_part | denotes | amino acid | http://purl.org/sig/ont/fma/fma82739 |
T39 | 1063-1073 | Body_part | denotes | amino acid | http://purl.org/sig/ont/fma/fma82739 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T26 | 43-47 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T27 | 130-138 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T28 | 155-163 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T29 | 277-285 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T30 | 366-374 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T31 | 546-554 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T32 | 734-742 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T33 | 838-846 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T34 | 928-936 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T34 | 293-294 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T35 | 451-456 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T36 | 476-478 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
T37 | 526-534 | http://purl.obolibrary.org/obo/NCBITaxon_9397 | denotes | this Bat |
T38 | 639-641 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T39 | 792-800 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signaled |
T40 | 829-834 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T41 | 1029-1032 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAS |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T41 | 31-39 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
T42 | 109-116 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T43 | 724-732 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
T44 | 866-876 | Chemical | denotes | amino acid | http://purl.obolibrary.org/obo/CHEBI_33709 |
T45 | 866-871 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
T46 | 872-876 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T47 | 1063-1073 | Chemical | denotes | amino acid | http://purl.obolibrary.org/obo/CHEBI_33709 |
T48 | 1063-1068 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
T49 | 1069-1073 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T53 | 0-73 | Sentence | denotes | Homology analysis of the spike proteins of SARS-CoVs and related Bat-CoVs |
T54 | 74-193 | Sentence | denotes | Phylogenetic analysis of the spike protein sequences of SARS-CoV-2 and Bat-CoVs, SARS-CoV is shown in Figure 1(Fig. 1). |
T55 | 194-481 | Sentence | denotes | The results are in agreement with recent reports of an independent introduction of SARS-CoV-2 from a Bat-CoV, different from the spillover which led to the introduction of SARS-CoV, being the Bat-CoV of Rhinolophus affinis the probable ancestor of this new virus (Wong et al., 2020[18]). |
T56 | 482-598 | Sentence | denotes | Indeed, the sequences of the whole spike of this Bat-CoV and of SARS-CoV-2 share 97.7 % identity (Figure 1(Fig. 1)). |
T57 | 599-733 | Sentence | denotes | More divergence is found however in the S1 subunit, particularly in the Receptor Binding Domain (RBD) of the different spike proteins. |
T58 | 734-939 | Sentence | denotes | SARS-CoV and Bat-CoV from Rhinolophus sinicus (originally signaled as the most closely related virus to SARS-CoV-2) exhibit several amino acid substitutions and deletions in the RBD compared to SARS-CoV-2. |
T59 | 940-1107 | Sentence | denotes | The RBD of Bat-CoV from Rhinolophus affinis, although more closely related to the one of SAS-CoV-2, also displayed several amino acid substitutions (Figure 2(Fig. 2)). |