PMC:7081066 / 5137-5975
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
159 | 81-85 | Gene | denotes | ACE2 | Gene:59272 |
160 | 357-361 | Gene | denotes | ACE2 | Gene:59272 |
161 | 496-501 | Gene | denotes | spike | Gene:43740568 |
162 | 525-529 | Gene | denotes | ACE2 | Gene:59272 |
163 | 347-352 | Gene | denotes | spike | Gene:43740568 |
164 | 186-191 | Gene | denotes | spike | Gene:43740568 |
165 | 55-60 | Gene | denotes | spike | Gene:43740568 |
166 | 46-54 | Species | denotes | SARS-CoV | Tax:694009 |
167 | 175-185 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T30 | 0-7 | Body_part | denotes | Protein | http://purl.org/sig/ont/fma/fma67257 |
T31 | 8-15 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T32 | 127-134 | Body_part | denotes | Protein | http://purl.org/sig/ont/fma/fma67257 |
T33 | 205-212 | Body_part | denotes | Protein | http://purl.org/sig/ont/fma/fma67257 |
T34 | 502-509 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T24 | 46-54 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T25 | 175-183 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T32 | 464-465 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T33 | 588-590 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T35 | 0-7 | Chemical | denotes | Protein | http://purl.obolibrary.org/obo/CHEBI_16541 |
T36 | 8-15 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T37 | 127-134 | Chemical | denotes | Protein | http://purl.obolibrary.org/obo/CHEBI_16541 |
T38 | 205-212 | Chemical | denotes | Protein | http://purl.obolibrary.org/obo/CHEBI_16541 |
T39 | 488-494 | Chemical | denotes | ligand | http://purl.obolibrary.org/obo/CHEBI_52214 |
T40 | 502-509 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T44 | 0-23 | Sentence | denotes | Protein-protein docking |
T45 | 24-145 | Sentence | denotes | Crystal structure for SARS-CoV spike (PDB code 6ACK) and ACE2 (PDB code 1R42) were downloaded from the Protein Data Bank. |
T46 | 146-204 | Sentence | denotes | Also, the homology model for SARS-CoV-2 spike was assayed. |
T47 | 205-260 | Sentence | denotes | Protein preparation was carried out as described above. |
T48 | 261-410 | Sentence | denotes | Then, binding patterns and affinity estimations for the interaction between the viral spike and ACE2 receptor were performed using molecular docking. |
T49 | 411-593 | Sentence | denotes | This process was performed through two steps; first, a blind docking between ligand (spike protein) and receptor (ACE2) was performed using Z-dock software (Pierce et al., 2014[11]). |
T50 | 594-717 | Sentence | denotes | Then, the resulting docking data were processed and analyzed by using the tools of PRODIGY software (Xue et al., 2016[19]). |
T51 | 718-838 | Sentence | denotes | Finally, results were clustered and analyzed considering binding energies and main interacting residues in each complex. |
MyTest
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32210742-24532726-29811233 | 588-590 | 24532726 | denotes | 11 |
32210742-27503228-29811234 | 712-714 | 27503228 | denotes | 19 |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32210742-24532726-29811233 | 588-590 | 24532726 | denotes | 11 |
32210742-27503228-29811234 | 712-714 | 27503228 | denotes | 19 |