PMC:7079862 / 24524-24874 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"876","span":{"begin":78,"end":86},"obj":"Species"},{"id":"877","span":{"begin":104,"end":108},"obj":"Species"},{"id":"880","span":{"begin":92,"end":101},"obj":"Species"},{"id":"885","span":{"begin":40,"end":49},"obj":"Chemical"},{"id":"886","span":{"begin":65,"end":74},"obj":"Chemical"},{"id":"887","span":{"begin":178,"end":189},"obj":"Chemical"},{"id":"889","span":{"begin":110,"end":119},"obj":"Disease"},{"id":"890","span":{"begin":238,"end":245},"obj":"Disease"},{"id":"891","span":{"begin":256,"end":273},"obj":"Disease"}],"attributes":[{"id":"A876","pred":"tao:has_database_id","subj":"876","obj":"Tax:9606"},{"id":"A877","pred":"tao:has_database_id","subj":"877","obj":"Tax:114727"},{"id":"A880","pred":"tao:has_database_id","subj":"880","obj":"Tax:11520"},{"id":"A885","pred":"tao:has_database_id","subj":"885","obj":"MESH:D020123"},{"id":"A886","pred":"tao:has_database_id","subj":"886","obj":"MESH:D020123"},{"id":"A887","pred":"tao:has_database_id","subj":"887","obj":"MESH:D053139"},{"id":"A889","pred":"tao:has_database_id","subj":"889","obj":"MESH:D011014"},{"id":"A890","pred":"tao:has_database_id","subj":"890","obj":"MESH:D000860"},{"id":"A891","pred":"tao:has_database_id","subj":"891","obj":"MESH:D009102"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In a small RCT (n = 28), treatment with sirolimus compared to no sirolimus in patients with influenza A(H1N1) pneumonia receiving invasive mechanical ventilation (in addition to oseltamivir and corticosteroids) resulted in improvement in hypoxia, multiple organ dysfunction and virus clearance, and in shorter duration of mechanical ventilation [34]."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T27","span":{"begin":256,"end":261},"obj":"Body_part"}],"attributes":[{"id":"A27","pred":"fma_id","subj":"T27","obj":"http://purl.org/sig/ont/fma/fma67498"}],"text":"In a small RCT (n = 28), treatment with sirolimus compared to no sirolimus in patients with influenza A(H1N1) pneumonia receiving invasive mechanical ventilation (in addition to oseltamivir and corticosteroids) resulted in improvement in hypoxia, multiple organ dysfunction and virus clearance, and in shorter duration of mechanical ventilation [34]."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T13","span":{"begin":256,"end":261},"obj":"Body_part"}],"attributes":[{"id":"A13","pred":"uberon_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/UBERON_0000062"}],"text":"In a small RCT (n = 28), treatment with sirolimus compared to no sirolimus in patients with influenza A(H1N1) pneumonia receiving invasive mechanical ventilation (in addition to oseltamivir and corticosteroids) resulted in improvement in hypoxia, multiple organ dysfunction and virus clearance, and in shorter duration of mechanical ventilation [34]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T165","span":{"begin":92,"end":109},"obj":"Disease"},{"id":"T166","span":{"begin":92,"end":101},"obj":"Disease"},{"id":"T167","span":{"begin":110,"end":119},"obj":"Disease"}],"attributes":[{"id":"A165","pred":"mondo_id","subj":"T165","obj":"http://purl.obolibrary.org/obo/MONDO_0005460"},{"id":"A166","pred":"mondo_id","subj":"T166","obj":"http://purl.obolibrary.org/obo/MONDO_0005812"},{"id":"A167","pred":"mondo_id","subj":"T167","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"}],"text":"In a small RCT (n = 28), treatment with sirolimus compared to no sirolimus in patients with influenza A(H1N1) pneumonia receiving invasive mechanical ventilation (in addition to oseltamivir and corticosteroids) resulted in improvement in hypoxia, multiple organ dysfunction and virus clearance, and in shorter duration of mechanical ventilation [34]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T184","span":{"begin":3,"end":4},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T185","span":{"begin":102,"end":103},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T186","span":{"begin":256,"end":261},"obj":"http://purl.obolibrary.org/obo/UBERON_0003103"},{"id":"T187","span":{"begin":278,"end":283},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T188","span":{"begin":346,"end":348},"obj":"http://purl.obolibrary.org/obo/CLO_0001302"}],"text":"In a small RCT (n = 28), treatment with sirolimus compared to no sirolimus in patients with influenza A(H1N1) pneumonia receiving invasive mechanical ventilation (in addition to oseltamivir and corticosteroids) resulted in improvement in hypoxia, multiple organ dysfunction and virus clearance, and in shorter duration of mechanical ventilation [34]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T215","span":{"begin":40,"end":49},"obj":"Chemical"},{"id":"T216","span":{"begin":65,"end":74},"obj":"Chemical"},{"id":"T217","span":{"begin":178,"end":189},"obj":"Chemical"},{"id":"T218","span":{"begin":194,"end":209},"obj":"Chemical"}],"attributes":[{"id":"A215","pred":"chebi_id","subj":"T215","obj":"http://purl.obolibrary.org/obo/CHEBI_9168"},{"id":"A216","pred":"chebi_id","subj":"T216","obj":"http://purl.obolibrary.org/obo/CHEBI_9168"},{"id":"A217","pred":"chebi_id","subj":"T217","obj":"http://purl.obolibrary.org/obo/CHEBI_7798"},{"id":"A218","pred":"chebi_id","subj":"T218","obj":"http://purl.obolibrary.org/obo/CHEBI_50858"}],"text":"In a small RCT (n = 28), treatment with sirolimus compared to no sirolimus in patients with influenza A(H1N1) pneumonia receiving invasive mechanical ventilation (in addition to oseltamivir and corticosteroids) resulted in improvement in hypoxia, multiple organ dysfunction and virus clearance, and in shorter duration of mechanical ventilation [34]."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T35","span":{"begin":110,"end":119},"obj":"Phenotype"},{"id":"T36","span":{"begin":238,"end":245},"obj":"Phenotype"}],"attributes":[{"id":"A35","pred":"hp_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A36","pred":"hp_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/HP_0012418"}],"text":"In a small RCT (n = 28), treatment with sirolimus compared to no sirolimus in patients with influenza A(H1N1) pneumonia receiving invasive mechanical ventilation (in addition to oseltamivir and corticosteroids) resulted in improvement in hypoxia, multiple organ dysfunction and virus clearance, and in shorter duration of mechanical ventilation [34]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T189","span":{"begin":0,"end":350},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In a small RCT (n = 28), treatment with sirolimus compared to no sirolimus in patients with influenza A(H1N1) pneumonia receiving invasive mechanical ventilation (in addition to oseltamivir and corticosteroids) resulted in improvement in hypoxia, multiple organ dysfunction and virus clearance, and in shorter duration of mechanical ventilation [34]."}

{"project":"2_test","denotations":[{"id":"32040667-24105455-47981310","span":{"begin":346,"end":348},"obj":"24105455"},{"id":"T46726","span":{"begin":346,"end":348},"obj":"24105455"}],"text":"In a small RCT (n = 28), treatment with sirolimus compared to no sirolimus in patients with influenza A(H1N1) pneumonia receiving invasive mechanical ventilation (in addition to oseltamivir and corticosteroids) resulted in improvement in hypoxia, multiple organ dysfunction and virus clearance, and in shorter duration of mechanical ventilation [34]."}