PMC:7079563 / 11911-13003 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7079563","sourcedb":"PMC","sourceid":"7079563","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7079563","text":"The epidemic of 2019-nCoV bears some similarities to SARS-CoV. The outbreaks of the two viruses occurred at about the same time during the year, and they were quite stable in the environment, especially in air-conditioned space, owing to lower ambient temperature and lower humidity [19]. However, SARS-CoV had an aberrant trait that the “viral load” in upper respiratory tract secretions was low in the first 5 days of illness, then increased progressively and peaked early in the second week. Consequently, the transmission rate was relatively low in the first days of illness, providing an opportunity for case detection and isolation to interrupt transmission. On the contrary, for 2019-nCoV, the incubation lasts for an average of 10 days (in a reported range of 2–14 days) from infection to symptoms surfacing [2,4,17,20]. Even worse, 2019-nCoV is able to spread from one person to another even before any actual clinical manifestations, leading to “extremely challenging” conditions for detecting and isolating potential patients, which makes it more difficult to control the 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