PMC:7077337 / 35388-37012 JSONTXT

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    LitCovid-PubTator

    {"project":"LitCovid-PubTator","denotations":[{"id":"1017","span":{"begin":135,"end":140},"obj":"Species"},{"id":"1018","span":{"begin":170,"end":176},"obj":"Species"},{"id":"1019","span":{"begin":178,"end":183},"obj":"Species"},{"id":"1020","span":{"begin":291,"end":296},"obj":"Species"},{"id":"1021","span":{"begin":408,"end":413},"obj":"Species"},{"id":"1022","span":{"begin":465,"end":471},"obj":"Species"},{"id":"1023","span":{"begin":481,"end":488},"obj":"Species"},{"id":"1024","span":{"begin":556,"end":561},"obj":"Species"},{"id":"1025","span":{"begin":689,"end":697},"obj":"Species"},{"id":"1026","span":{"begin":591,"end":600},"obj":"Disease"},{"id":"1027","span":{"begin":635,"end":641},"obj":"Disease"},{"id":"1029","span":{"begin":1089,"end":1097},"obj":"Species"},{"id":"1036","span":{"begin":1241,"end":1246},"obj":"Species"},{"id":"1037","span":{"begin":1338,"end":1343},"obj":"Species"},{"id":"1038","span":{"begin":1481,"end":1486},"obj":"Species"},{"id":"1039","span":{"begin":1442,"end":1451},"obj":"Chemical"},{"id":"1040","span":{"begin":1525,"end":1534},"obj":"Chemical"},{"id":"1041","span":{"begin":1427,"end":1431},"obj":"Disease"}],"attributes":[{"id":"A1017","pred":"tao:has_database_id","subj":"1017","obj":"Tax:9606"},{"id":"A1018","pred":"tao:has_database_id","subj":"1018","obj":"Tax:9838"},{"id":"A1019","pred":"tao:has_database_id","subj":"1019","obj":"Tax:9838"},{"id":"A1020","pred":"tao:has_database_id","subj":"1020","obj":"Tax:9606"},{"id":"A1021","pred":"tao:has_database_id","subj":"1021","obj":"Tax:9606"},{"id":"A1022","pred":"tao:has_database_id","subj":"1022","obj":"Tax:9838"},{"id":"A1023","pred":"tao:has_database_id","subj":"1023","obj":"Tax:9606"},{"id":"A1024","pred":"tao:has_database_id","subj":"1024","obj":"Tax:9606"},{"id":"A1025","pred":"tao:has_database_id","subj":"1025","obj":"Tax:1335626"},{"id":"A1026","pred":"tao:has_database_id","subj":"1026","obj":"MESH:D011014"},{"id":"A1027","pred":"tao:has_database_id","subj":"1027","obj":"MESH:D018805"},{"id":"A1029","pred":"tao:has_database_id","subj":"1029","obj":"Tax:1335626"},{"id":"A1036","pred":"tao:has_database_id","subj":"1036","obj":"Tax:9606"},{"id":"A1037","pred":"tao:has_database_id","subj":"1037","obj":"Tax:9606"},{"id":"A1038","pred":"tao:has_database_id","subj":"1038","obj":"Tax:9606"},{"id":"A1039","pred":"tao:has_database_id","subj":"1039","obj":"MESH:D012254"},{"id":"A1040","pred":"tao:has_database_id","subj":"1040","obj":"MESH:D012254"},{"id":"A1041","pred":"tao:has_database_id","subj":"1041","obj":"MESH:D045169"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"10. MERS Prevention and Treatment\nMERS prevention should be high priority for high-risk exposures such as healthcare workers, pregnant women and individuals working with camels, camel meat-milk processors and in abattoirs [57]. Since 2013, the Saudi Arabia MoH has recommended that pregnant women postpone travel to Saudi Arabia for the Hajj and Umrah [47]. To further reduce risk of exposure among pregnant women, additional measures such as avoiding contact with camels and sick persons—particularly in healthcare settings—are also recommended. Pregnant women who present with symptoms of pneumonia, influenza-like illness (ILI), or sepsis on the Arabian Peninsula may also benefit from MERS-CoV screening to expedite early diagnosis and improve disease management [60].\nWhile multiple agents have been used to treat MERS, none have been tested in large clinical studies. Available data are limited to the use of combination therapies of interferon and other agents in case reports and case series [63]. A prospective or randomized study may prove difficult given the sporadic nature of MERS-CoV outbreaks.\nDue to a gap in research on the treatment of MERS in pregnancy, there are no therapeutic options currently recommended for pregnant women [58]. Therapies under development and testing may be considered inappropriate for pregnant women due to the unknown potential for teratogenic effects. For example, during the 2003 SARS outbreak, ribavirin was administered to pregnant women with severe cases of the disease, but ribavirin therapy has been documented to increase the risk of teratogenic effects in newborns [58]."}

    LitCovid-PD-FMA-UBERON

    {"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T83","span":{"begin":189,"end":193},"obj":"Body_part"}],"attributes":[{"id":"A83","pred":"fma_id","subj":"T83","obj":"http://purl.org/sig/ont/fma/fma62100"}],"text":"10. MERS Prevention and Treatment\nMERS prevention should be high priority for high-risk exposures such as healthcare workers, pregnant women and individuals working with camels, camel meat-milk processors and in abattoirs [57]. Since 2013, the Saudi Arabia MoH has recommended that pregnant women postpone travel to Saudi Arabia for the Hajj and Umrah [47]. To further reduce risk of exposure among pregnant women, additional measures such as avoiding contact with camels and sick persons—particularly in healthcare settings—are also recommended. Pregnant women who present with symptoms of pneumonia, influenza-like illness (ILI), or sepsis on the Arabian Peninsula may also benefit from MERS-CoV screening to expedite early diagnosis and improve disease management [60].\nWhile multiple agents have been used to treat MERS, none have been tested in large clinical studies. Available data are limited to the use of combination therapies of interferon and other agents in case reports and case series [63]. A prospective or randomized study may prove difficult given the sporadic nature of MERS-CoV outbreaks.\nDue to a gap in research on the treatment of MERS in pregnancy, there are no therapeutic options currently recommended for pregnant women [58]. Therapies under development and testing may be considered inappropriate for pregnant women due to the unknown potential for teratogenic effects. For example, during the 2003 SARS outbreak, ribavirin was administered to pregnant women with severe cases of the disease, but ribavirin therapy has been documented to increase the risk of teratogenic effects in newborns [58]."}

    LitCovid-PD-UBERON

    {"project":"LitCovid-PD-UBERON","denotations":[{"id":"T64","span":{"begin":189,"end":193},"obj":"Body_part"}],"attributes":[{"id":"A64","pred":"uberon_id","subj":"T64","obj":"http://purl.obolibrary.org/obo/UBERON_0001913"}],"text":"10. MERS Prevention and Treatment\nMERS prevention should be high priority for high-risk exposures such as healthcare workers, pregnant women and individuals working with camels, camel meat-milk processors and in abattoirs [57]. Since 2013, the Saudi Arabia MoH has recommended that pregnant women postpone travel to Saudi Arabia for the Hajj and Umrah [47]. To further reduce risk of exposure among pregnant women, additional measures such as avoiding contact with camels and sick persons—particularly in healthcare settings—are also recommended. Pregnant women who present with symptoms of pneumonia, influenza-like illness (ILI), or sepsis on the Arabian Peninsula may also benefit from MERS-CoV screening to expedite early diagnosis and improve disease management [60].\nWhile multiple agents have been used to treat MERS, none have been tested in large clinical studies. Available data are limited to the use of combination therapies of interferon and other agents in case reports and case series [63]. A prospective or randomized study may prove difficult given the sporadic nature of MERS-CoV outbreaks.\nDue to a gap in research on the treatment of MERS in pregnancy, there are no therapeutic options currently recommended for pregnant women [58]. Therapies under development and testing may be considered inappropriate for pregnant women due to the unknown potential for teratogenic effects. For example, during the 2003 SARS outbreak, ribavirin was administered to pregnant women with severe cases of the disease, but ribavirin therapy has been documented to increase the risk of teratogenic effects in newborns [58]."}

    LitCovid-PD-MONDO

    {"project":"LitCovid-PD-MONDO","denotations":[{"id":"T252","span":{"begin":591,"end":600},"obj":"Disease"},{"id":"T253","span":{"begin":602,"end":611},"obj":"Disease"},{"id":"T254","span":{"begin":1427,"end":1431},"obj":"Disease"}],"attributes":[{"id":"A252","pred":"mondo_id","subj":"T252","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A253","pred":"mondo_id","subj":"T253","obj":"http://purl.obolibrary.org/obo/MONDO_0005812"},{"id":"A254","pred":"mondo_id","subj":"T254","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"10. MERS Prevention and Treatment\nMERS prevention should be high priority for high-risk exposures such as healthcare workers, pregnant women and individuals working with camels, camel meat-milk processors and in abattoirs [57]. Since 2013, the Saudi Arabia MoH has recommended that pregnant women postpone travel to Saudi Arabia for the Hajj and Umrah [47]. To further reduce risk of exposure among pregnant women, additional measures such as avoiding contact with camels and sick persons—particularly in healthcare settings—are also recommended. Pregnant women who present with symptoms of pneumonia, influenza-like illness (ILI), or sepsis on the Arabian Peninsula may also benefit from MERS-CoV screening to expedite early diagnosis and improve disease management [60].\nWhile multiple agents have been used to treat MERS, none have been tested in large clinical studies. Available data are limited to the use of combination therapies of interferon and other agents in case reports and case series [63]. A prospective or randomized study may prove difficult given the sporadic nature of MERS-CoV outbreaks.\nDue to a gap in research on the treatment of MERS in pregnancy, there are no therapeutic options currently recommended for pregnant women [58]. Therapies under development and testing may be considered inappropriate for pregnant women due to the unknown potential for teratogenic effects. For example, during the 2003 SARS outbreak, ribavirin was administered to pregnant women with severe cases of the disease, but ribavirin therapy has been documented to increase the risk of teratogenic effects in newborns [58]."}

    LitCovid-PD-CLO

    {"project":"LitCovid-PD-CLO","denotations":[{"id":"T249","span":{"begin":170,"end":176},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9837"},{"id":"T250","span":{"begin":178,"end":183},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9837"},{"id":"T251","span":{"begin":261,"end":264},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T252","span":{"begin":465,"end":471},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9837"},{"id":"T253","span":{"begin":840,"end":846},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T254","span":{"begin":1006,"end":1007},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T255","span":{"begin":1116,"end":1117},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T256","span":{"begin":1285,"end":1292},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T257","span":{"begin":1543,"end":1546},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"}],"text":"10. MERS Prevention and Treatment\nMERS prevention should be high priority for high-risk exposures such as healthcare workers, pregnant women and individuals working with camels, camel meat-milk processors and in abattoirs [57]. Since 2013, the Saudi Arabia MoH has recommended that pregnant women postpone travel to Saudi Arabia for the Hajj and Umrah [47]. To further reduce risk of exposure among pregnant women, additional measures such as avoiding contact with camels and sick persons—particularly in healthcare settings—are also recommended. Pregnant women who present with symptoms of pneumonia, influenza-like illness (ILI), or sepsis on the Arabian Peninsula may also benefit from MERS-CoV screening to expedite early diagnosis and improve disease management [60].\nWhile multiple agents have been used to treat MERS, none have been tested in large clinical studies. Available data are limited to the use of combination therapies of interferon and other agents in case reports and case series [63]. A prospective or randomized study may prove difficult given the sporadic nature of MERS-CoV outbreaks.\nDue to a gap in research on the treatment of MERS in pregnancy, there are no therapeutic options currently recommended for pregnant women [58]. Therapies under development and testing may be considered inappropriate for pregnant women due to the unknown potential for teratogenic effects. For example, during the 2003 SARS outbreak, ribavirin was administered to pregnant women with severe cases of the disease, but ribavirin therapy has been documented to increase the risk of teratogenic effects in newborns [58]."}

    LitCovid-PD-CHEBI

    {"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T17","span":{"begin":940,"end":950},"obj":"Chemical"},{"id":"T18","span":{"begin":1442,"end":1451},"obj":"Chemical"},{"id":"T19","span":{"begin":1525,"end":1534},"obj":"Chemical"}],"attributes":[{"id":"A17","pred":"chebi_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_52999"},{"id":"A18","pred":"chebi_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/CHEBI_63580"},{"id":"A19","pred":"chebi_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/CHEBI_63580"}],"text":"10. MERS Prevention and Treatment\nMERS prevention should be high priority for high-risk exposures such as healthcare workers, pregnant women and individuals working with camels, camel meat-milk processors and in abattoirs [57]. Since 2013, the Saudi Arabia MoH has recommended that pregnant women postpone travel to Saudi Arabia for the Hajj and Umrah [47]. To further reduce risk of exposure among pregnant women, additional measures such as avoiding contact with camels and sick persons—particularly in healthcare settings—are also recommended. Pregnant women who present with symptoms of pneumonia, influenza-like illness (ILI), or sepsis on the Arabian Peninsula may also benefit from MERS-CoV screening to expedite early diagnosis and improve disease management [60].\nWhile multiple agents have been used to treat MERS, none have been tested in large clinical studies. Available data are limited to the use of combination therapies of interferon and other agents in case reports and case series [63]. A prospective or randomized study may prove difficult given the sporadic nature of MERS-CoV outbreaks.\nDue to a gap in research on the treatment of MERS in pregnancy, there are no therapeutic options currently recommended for pregnant women [58]. Therapies under development and testing may be considered inappropriate for pregnant women due to the unknown potential for teratogenic effects. For example, during the 2003 SARS outbreak, ribavirin was administered to pregnant women with severe cases of the disease, but ribavirin therapy has been documented to increase the risk of teratogenic effects in newborns [58]."}

    LitCovid-PD-HP

    {"project":"LitCovid-PD-HP","denotations":[{"id":"T91","span":{"begin":591,"end":600},"obj":"Phenotype"},{"id":"T92","span":{"begin":635,"end":641},"obj":"Phenotype"}],"attributes":[{"id":"A91","pred":"hp_id","subj":"T91","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A92","pred":"hp_id","subj":"T92","obj":"http://purl.obolibrary.org/obo/HP_0100806"}],"text":"10. MERS Prevention and Treatment\nMERS prevention should be high priority for high-risk exposures such as healthcare workers, pregnant women and individuals working with camels, camel meat-milk processors and in abattoirs [57]. Since 2013, the Saudi Arabia MoH has recommended that pregnant women postpone travel to Saudi Arabia for the Hajj and Umrah [47]. To further reduce risk of exposure among pregnant women, additional measures such as avoiding contact with camels and sick persons—particularly in healthcare settings—are also recommended. Pregnant women who present with symptoms of pneumonia, influenza-like illness (ILI), or sepsis on the Arabian Peninsula may also benefit from MERS-CoV screening to expedite early diagnosis and improve disease management [60].\nWhile multiple agents have been used to treat MERS, none have been tested in large clinical studies. Available data are limited to the use of combination therapies of interferon and other agents in case reports and case series [63]. A prospective or randomized study may prove difficult given the sporadic nature of MERS-CoV outbreaks.\nDue to a gap in research on the treatment of MERS in pregnancy, there are no therapeutic options currently recommended for pregnant women [58]. Therapies under development and testing may be considered inappropriate for pregnant women due to the unknown potential for teratogenic effects. For example, during the 2003 SARS outbreak, ribavirin was administered to pregnant women with severe cases of the disease, but ribavirin therapy has been documented to increase the risk of teratogenic effects in newborns [58]."}

    LitCovid-sentences

    {"project":"LitCovid-sentences","denotations":[{"id":"T240","span":{"begin":0,"end":3},"obj":"Sentence"},{"id":"T241","span":{"begin":4,"end":33},"obj":"Sentence"},{"id":"T242","span":{"begin":34,"end":227},"obj":"Sentence"},{"id":"T243","span":{"begin":228,"end":357},"obj":"Sentence"},{"id":"T244","span":{"begin":358,"end":546},"obj":"Sentence"},{"id":"T245","span":{"begin":547,"end":772},"obj":"Sentence"},{"id":"T246","span":{"begin":773,"end":873},"obj":"Sentence"},{"id":"T247","span":{"begin":874,"end":1005},"obj":"Sentence"},{"id":"T248","span":{"begin":1006,"end":1108},"obj":"Sentence"},{"id":"T249","span":{"begin":1109,"end":1252},"obj":"Sentence"},{"id":"T250","span":{"begin":1253,"end":1397},"obj":"Sentence"},{"id":"T251","span":{"begin":1398,"end":1624},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"10. MERS Prevention and Treatment\nMERS prevention should be high priority for high-risk exposures such as healthcare workers, pregnant women and individuals working with camels, camel meat-milk processors and in abattoirs [57]. Since 2013, the Saudi Arabia MoH has recommended that pregnant women postpone travel to Saudi Arabia for the Hajj and Umrah [47]. To further reduce risk of exposure among pregnant women, additional measures such as avoiding contact with camels and sick persons—particularly in healthcare settings—are also recommended. Pregnant women who present with symptoms of pneumonia, influenza-like illness (ILI), or sepsis on the Arabian Peninsula may also benefit from MERS-CoV screening to expedite early diagnosis and improve disease management [60].\nWhile multiple agents have been used to treat MERS, none have been tested in large clinical studies. Available data are limited to the use of combination therapies of interferon and other agents in case reports and case series [63]. A prospective or randomized study may prove difficult given the sporadic nature of MERS-CoV outbreaks.\nDue to a gap in research on the treatment of MERS in pregnancy, there are no therapeutic options currently recommended for pregnant women [58]. Therapies under development and testing may be considered inappropriate for pregnant women due to the unknown potential for teratogenic effects. For example, during the 2003 SARS outbreak, ribavirin was administered to pregnant women with severe cases of the disease, but ribavirin therapy has been documented to increase the risk of teratogenic effects in newborns [58]."}

    2_test

    {"project":"2_test","denotations":[{"id":"32050635-26256102-144359594","span":{"begin":223,"end":225},"obj":"26256102"},{"id":"32050635-27358348-144359595","span":{"begin":353,"end":355},"obj":"27358348"},{"id":"32050635-26890613-144359596","span":{"begin":768,"end":770},"obj":"26890613"},{"id":"32050635-27937060-144359597","span":{"begin":1001,"end":1003},"obj":"27937060"},{"id":"32050635-26936356-144359598","span":{"begin":1248,"end":1250},"obj":"26936356"},{"id":"32050635-26936356-144359599","span":{"begin":1620,"end":1622},"obj":"26936356"}],"text":"10. MERS Prevention and Treatment\nMERS prevention should be high priority for high-risk exposures such as healthcare workers, pregnant women and individuals working with camels, camel meat-milk processors and in abattoirs [57]. Since 2013, the Saudi Arabia MoH has recommended that pregnant women postpone travel to Saudi Arabia for the Hajj and Umrah [47]. To further reduce risk of exposure among pregnant women, additional measures such as avoiding contact with camels and sick persons—particularly in healthcare settings—are also recommended. Pregnant women who present with symptoms of pneumonia, influenza-like illness (ILI), or sepsis on the Arabian Peninsula may also benefit from MERS-CoV screening to expedite early diagnosis and improve disease management [60].\nWhile multiple agents have been used to treat MERS, none have been tested in large clinical studies. Available data are limited to the use of combination therapies of interferon and other agents in case reports and case series [63]. A prospective or randomized study may prove difficult given the sporadic nature of MERS-CoV outbreaks.\nDue to a gap in research on the treatment of MERS in pregnancy, there are no therapeutic options currently recommended for pregnant women [58]. Therapies under development and testing may be considered inappropriate for pregnant women due to the unknown potential for teratogenic effects. For example, during the 2003 SARS outbreak, ribavirin was administered to pregnant women with severe cases of the disease, but ribavirin therapy has been documented to increase the risk of teratogenic effects in newborns [58]."}