PMC:7077191 / 20423-21283
Annnotations
LitCovid-PubTator
{"project":"LitCovid-PubTator","denotations":[{"id":"620","span":{"begin":324,"end":325},"obj":"Gene"},{"id":"621","span":{"begin":105,"end":106},"obj":"Gene"},{"id":"622","span":{"begin":32,"end":36},"obj":"Species"},{"id":"623","span":{"begin":90,"end":94},"obj":"Species"},{"id":"624","span":{"begin":118,"end":128},"obj":"Species"},{"id":"625","span":{"begin":174,"end":182},"obj":"Species"},{"id":"626","span":{"begin":246,"end":254},"obj":"Species"},{"id":"627","span":{"begin":304,"end":314},"obj":"Species"},{"id":"628","span":{"begin":434,"end":442},"obj":"Species"},{"id":"629","span":{"begin":529,"end":539},"obj":"Species"},{"id":"630","span":{"begin":624,"end":632},"obj":"Species"},{"id":"631","span":{"begin":685,"end":695},"obj":"Species"},{"id":"632","span":{"begin":364,"end":384},"obj":"Disease"},{"id":"633","span":{"begin":540,"end":548},"obj":"Disease"},{"id":"634","span":{"begin":739,"end":748},"obj":"Disease"},{"id":"635","span":{"begin":849,"end":859},"obj":"Disease"}],"attributes":[{"id":"A620","pred":"tao:has_database_id","subj":"620","obj":"Gene:43740575"},{"id":"A621","pred":"tao:has_database_id","subj":"621","obj":"Gene:43740575"},{"id":"A622","pred":"tao:has_database_id","subj":"622","obj":"Tax:11118"},{"id":"A623","pred":"tao:has_database_id","subj":"623","obj":"Tax:11118"},{"id":"A624","pred":"tao:has_database_id","subj":"624","obj":"Tax:2697049"},{"id":"A625","pred":"tao:has_database_id","subj":"625","obj":"Tax:694009"},{"id":"A626","pred":"tao:has_database_id","subj":"626","obj":"Tax:694009"},{"id":"A627","pred":"tao:has_database_id","subj":"627","obj":"Tax:2697049"},{"id":"A628","pred":"tao:has_database_id","subj":"628","obj":"Tax:694009"},{"id":"A629","pred":"tao:has_database_id","subj":"629","obj":"Tax:2697049"},{"id":"A630","pred":"tao:has_database_id","subj":"630","obj":"Tax:694009"},{"id":"A631","pred":"tao:has_database_id","subj":"631","obj":"Tax:2697049"},{"id":"A632","pred":"tao:has_database_id","subj":"632","obj":"MESH:C000657245"},{"id":"A633","pred":"tao:has_database_id","subj":"633","obj":"MESH:D007239"},{"id":"A634","pred":"tao:has_database_id","subj":"634","obj":"MESH:D007239"},{"id":"A635","pred":"tao:has_database_id","subj":"635","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"As the most abundant protein in CoVs, nucleocapsid (N) protein is highly conserved across CoVs [91]. The N protein in SARS-CoV-2 shares ~90% amino acid identity with that in SARS-CoV [28], which indicates that antibodies against the N protein of SARS-CoV would likely recognize and bind the N protein of SARS-CoV-2 as well. N antibodies do not provide immunity to SARS-CoV-2 infection, but the antibodies have a cross reactivity with SARS-CoV N protein viruses, which would allow a serum-based assay to identify the asymptomatic SARS-CoV-2 infected-cases [28]. Although previous studies have found serum reactivity to group SARS-CoV N proteins in Chinese populations [92], exposure to SARS-CoV-2 should increase the dilution factor if the infection had occurred. This information has important implications for preventing the spread of asymptomatic infections."}
LitCovid-PD-FMA-UBERON
{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T49","span":{"begin":21,"end":28},"obj":"Body_part"},{"id":"T50","span":{"begin":55,"end":62},"obj":"Body_part"},{"id":"T51","span":{"begin":107,"end":114},"obj":"Body_part"},{"id":"T52","span":{"begin":141,"end":151},"obj":"Body_part"},{"id":"T53","span":{"begin":235,"end":242},"obj":"Body_part"},{"id":"T54","span":{"begin":293,"end":300},"obj":"Body_part"},{"id":"T55","span":{"begin":445,"end":452},"obj":"Body_part"},{"id":"T56","span":{"begin":482,"end":487},"obj":"Body_part"},{"id":"T57","span":{"begin":598,"end":603},"obj":"Body_part"},{"id":"T58","span":{"begin":635,"end":643},"obj":"Body_part"}],"attributes":[{"id":"A49","pred":"fma_id","subj":"T49","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A50","pred":"fma_id","subj":"T50","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A51","pred":"fma_id","subj":"T51","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A52","pred":"fma_id","subj":"T52","obj":"http://purl.org/sig/ont/fma/fma82739"},{"id":"A53","pred":"fma_id","subj":"T53","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A54","pred":"fma_id","subj":"T54","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A55","pred":"fma_id","subj":"T55","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A56","pred":"fma_id","subj":"T56","obj":"http://purl.org/sig/ont/fma/fma63083"},{"id":"A57","pred":"fma_id","subj":"T57","obj":"http://purl.org/sig/ont/fma/fma63083"},{"id":"A58","pred":"fma_id","subj":"T58","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"As the most abundant protein in CoVs, nucleocapsid (N) protein is highly conserved across CoVs [91]. The N protein in SARS-CoV-2 shares ~90% amino acid identity with that in SARS-CoV [28], which indicates that antibodies against the N protein of SARS-CoV would likely recognize and bind the N protein of SARS-CoV-2 as well. N antibodies do not provide immunity to SARS-CoV-2 infection, but the antibodies have a cross reactivity with SARS-CoV N protein viruses, which would allow a serum-based assay to identify the asymptomatic SARS-CoV-2 infected-cases [28]. Although previous studies have found serum reactivity to group SARS-CoV N proteins in Chinese populations [92], exposure to SARS-CoV-2 should increase the dilution factor if the infection had occurred. This information has important implications for preventing the spread of asymptomatic infections."}
LitCovid-PD-UBERON
{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T15","span":{"begin":482,"end":487},"obj":"Body_part"},{"id":"T16","span":{"begin":598,"end":603},"obj":"Body_part"}],"attributes":[{"id":"A15","pred":"uberon_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/UBERON_0001977"},{"id":"A16","pred":"uberon_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/UBERON_0001977"}],"text":"As the most abundant protein in CoVs, nucleocapsid (N) protein is highly conserved across CoVs [91]. The N protein in SARS-CoV-2 shares ~90% amino acid identity with that in SARS-CoV [28], which indicates that antibodies against the N protein of SARS-CoV would likely recognize and bind the N protein of SARS-CoV-2 as well. N antibodies do not provide immunity to SARS-CoV-2 infection, but the antibodies have a cross reactivity with SARS-CoV N protein viruses, which would allow a serum-based assay to identify the asymptomatic SARS-CoV-2 infected-cases [28]. Although previous studies have found serum reactivity to group SARS-CoV N proteins in Chinese populations [92], exposure to SARS-CoV-2 should increase the dilution factor if the infection had occurred. This information has important implications for preventing the spread of asymptomatic infections."}
LitCovid-PD-MONDO
{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T254","span":{"begin":118,"end":126},"obj":"Disease"},{"id":"T255","span":{"begin":118,"end":122},"obj":"Disease"},{"id":"T256","span":{"begin":174,"end":182},"obj":"Disease"},{"id":"T257","span":{"begin":174,"end":178},"obj":"Disease"},{"id":"T258","span":{"begin":246,"end":254},"obj":"Disease"},{"id":"T259","span":{"begin":246,"end":250},"obj":"Disease"},{"id":"T260","span":{"begin":304,"end":312},"obj":"Disease"},{"id":"T261","span":{"begin":304,"end":308},"obj":"Disease"},{"id":"T262","span":{"begin":364,"end":372},"obj":"Disease"},{"id":"T263","span":{"begin":364,"end":368},"obj":"Disease"},{"id":"T264","span":{"begin":375,"end":384},"obj":"Disease"},{"id":"T265","span":{"begin":434,"end":442},"obj":"Disease"},{"id":"T266","span":{"begin":434,"end":438},"obj":"Disease"},{"id":"T267","span":{"begin":529,"end":537},"obj":"Disease"},{"id":"T268","span":{"begin":529,"end":533},"obj":"Disease"},{"id":"T269","span":{"begin":624,"end":632},"obj":"Disease"},{"id":"T270","span":{"begin":624,"end":628},"obj":"Disease"},{"id":"T271","span":{"begin":685,"end":693},"obj":"Disease"},{"id":"T272","span":{"begin":685,"end":689},"obj":"Disease"},{"id":"T273","span":{"begin":739,"end":748},"obj":"Disease"},{"id":"T274","span":{"begin":849,"end":859},"obj":"Disease"}],"attributes":[{"id":"A254","pred":"mondo_id","subj":"T254","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A255","pred":"mondo_id","subj":"T255","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A256","pred":"mondo_id","subj":"T256","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A257","pred":"mondo_id","subj":"T257","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A258","pred":"mondo_id","subj":"T258","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A259","pred":"mondo_id","subj":"T259","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A260","pred":"mondo_id","subj":"T260","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A261","pred":"mondo_id","subj":"T261","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A262","pred":"mondo_id","subj":"T262","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A263","pred":"mondo_id","subj":"T263","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A264","pred":"mondo_id","subj":"T264","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A265","pred":"mondo_id","subj":"T265","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A266","pred":"mondo_id","subj":"T266","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A267","pred":"mondo_id","subj":"T267","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A268","pred":"mondo_id","subj":"T268","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A269","pred":"mondo_id","subj":"T269","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A270","pred":"mondo_id","subj":"T270","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A271","pred":"mondo_id","subj":"T271","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A272","pred":"mondo_id","subj":"T272","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A273","pred":"mondo_id","subj":"T273","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A274","pred":"mondo_id","subj":"T274","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"As the most abundant protein in CoVs, nucleocapsid (N) protein is highly conserved across CoVs [91]. The N protein in SARS-CoV-2 shares ~90% amino acid identity with that in SARS-CoV [28], which indicates that antibodies against the N protein of SARS-CoV would likely recognize and bind the N protein of SARS-CoV-2 as well. N antibodies do not provide immunity to SARS-CoV-2 infection, but the antibodies have a cross reactivity with SARS-CoV N protein viruses, which would allow a serum-based assay to identify the asymptomatic SARS-CoV-2 infected-cases [28]. Although previous studies have found serum reactivity to group SARS-CoV N proteins in Chinese populations [92], exposure to SARS-CoV-2 should increase the dilution factor if the infection had occurred. This information has important implications for preventing the spread of asymptomatic infections."}
LitCovid-PD-CLO
{"project":"LitCovid-PD-CLO","denotations":[{"id":"T187","span":{"begin":410,"end":411},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T188","span":{"begin":453,"end":460},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T189","span":{"begin":480,"end":481},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T190","span":{"begin":780,"end":783},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"}],"text":"As the most abundant protein in CoVs, nucleocapsid (N) protein is highly conserved across CoVs [91]. The N protein in SARS-CoV-2 shares ~90% amino acid identity with that in SARS-CoV [28], which indicates that antibodies against the N protein of SARS-CoV would likely recognize and bind the N protein of SARS-CoV-2 as well. N antibodies do not provide immunity to SARS-CoV-2 infection, but the antibodies have a cross reactivity with SARS-CoV N protein viruses, which would allow a serum-based assay to identify the asymptomatic SARS-CoV-2 infected-cases [28]. Although previous studies have found serum reactivity to group SARS-CoV N proteins in Chinese populations [92], exposure to SARS-CoV-2 should increase the dilution factor if the infection had occurred. This information has important implications for preventing the spread of asymptomatic infections."}
LitCovid-PD-CHEBI
{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T81","span":{"begin":21,"end":28},"obj":"Chemical"},{"id":"T82","span":{"begin":55,"end":62},"obj":"Chemical"},{"id":"T83","span":{"begin":107,"end":114},"obj":"Chemical"},{"id":"T84","span":{"begin":141,"end":151},"obj":"Chemical"},{"id":"T85","span":{"begin":141,"end":146},"obj":"Chemical"},{"id":"T86","span":{"begin":147,"end":151},"obj":"Chemical"},{"id":"T87","span":{"begin":235,"end":242},"obj":"Chemical"},{"id":"T88","span":{"begin":293,"end":300},"obj":"Chemical"},{"id":"T89","span":{"begin":445,"end":452},"obj":"Chemical"},{"id":"T90","span":{"begin":618,"end":623},"obj":"Chemical"},{"id":"T91","span":{"begin":635,"end":643},"obj":"Chemical"}],"attributes":[{"id":"A81","pred":"chebi_id","subj":"T81","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A82","pred":"chebi_id","subj":"T82","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A83","pred":"chebi_id","subj":"T83","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A84","pred":"chebi_id","subj":"T84","obj":"http://purl.obolibrary.org/obo/CHEBI_33709"},{"id":"A85","pred":"chebi_id","subj":"T85","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"},{"id":"A86","pred":"chebi_id","subj":"T86","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A87","pred":"chebi_id","subj":"T87","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A88","pred":"chebi_id","subj":"T88","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A89","pred":"chebi_id","subj":"T89","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A90","pred":"chebi_id","subj":"T90","obj":"http://purl.obolibrary.org/obo/CHEBI_24433"},{"id":"A91","pred":"chebi_id","subj":"T91","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"As the most abundant protein in CoVs, nucleocapsid (N) protein is highly conserved across CoVs [91]. The N protein in SARS-CoV-2 shares ~90% amino acid identity with that in SARS-CoV [28], which indicates that antibodies against the N protein of SARS-CoV would likely recognize and bind the N protein of SARS-CoV-2 as well. N antibodies do not provide immunity to SARS-CoV-2 infection, but the antibodies have a cross reactivity with SARS-CoV N protein viruses, which would allow a serum-based assay to identify the asymptomatic SARS-CoV-2 infected-cases [28]. Although previous studies have found serum reactivity to group SARS-CoV N proteins in Chinese populations [92], exposure to SARS-CoV-2 should increase the dilution factor if the infection had occurred. This information has important implications for preventing the spread of asymptomatic infections."}
LitCovid-sentences
{"project":"LitCovid-sentences","denotations":[{"id":"T190","span":{"begin":0,"end":100},"obj":"Sentence"},{"id":"T191","span":{"begin":101,"end":323},"obj":"Sentence"},{"id":"T192","span":{"begin":324,"end":560},"obj":"Sentence"},{"id":"T193","span":{"begin":561,"end":762},"obj":"Sentence"},{"id":"T194","span":{"begin":763,"end":860},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"As the most abundant protein in CoVs, nucleocapsid (N) protein is highly conserved across CoVs [91]. The N protein in SARS-CoV-2 shares ~90% amino acid identity with that in SARS-CoV [28], which indicates that antibodies against the N protein of SARS-CoV would likely recognize and bind the N protein of SARS-CoV-2 as well. N antibodies do not provide immunity to SARS-CoV-2 infection, but the antibodies have a cross reactivity with SARS-CoV N protein viruses, which would allow a serum-based assay to identify the asymptomatic SARS-CoV-2 infected-cases [28]. Although previous studies have found serum reactivity to group SARS-CoV N proteins in Chinese populations [92], exposure to SARS-CoV-2 should increase the dilution factor if the infection had occurred. This information has important implications for preventing the spread of asymptomatic infections."}
2_test
{"project":"2_test","denotations":[{"id":"32098422-28214731-144407013","span":{"begin":96,"end":98},"obj":"28214731"},{"id":"32098422-31991541-144407014","span":{"begin":184,"end":186},"obj":"31991541"},{"id":"32098422-31991541-144407015","span":{"begin":556,"end":558},"obj":"31991541"},{"id":"32098422-29500691-144407016","span":{"begin":668,"end":670},"obj":"29500691"}],"text":"As the most abundant protein in CoVs, nucleocapsid (N) protein is highly conserved across CoVs [91]. The N protein in SARS-CoV-2 shares ~90% amino acid identity with that in SARS-CoV [28], which indicates that antibodies against the N protein of SARS-CoV would likely recognize and bind the N protein of SARS-CoV-2 as well. N antibodies do not provide immunity to SARS-CoV-2 infection, but the antibodies have a cross reactivity with SARS-CoV N protein viruses, which would allow a serum-based assay to identify the asymptomatic SARS-CoV-2 infected-cases [28]. Although previous studies have found serum reactivity to group SARS-CoV N proteins in Chinese populations [92], exposure to SARS-CoV-2 should increase the dilution factor if the infection had occurred. This information has important implications for preventing the spread of asymptomatic infections."}