PMC:7076992 / 54-2072
Annnotations
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T2 | 23-31 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T3 | 53-61 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T4 | 193-202 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T5 | 391-399 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T6 | 402-411 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T7 | 455-490 | Disease | denotes | acute respiratory distress syndrome | http://purl.obolibrary.org/obo/MONDO_0006502 |
| T8 | 461-490 | Disease | denotes | respiratory distress syndrome | http://purl.obolibrary.org/obo/MONDO_0009971 |
| T9 | 892-900 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T10 | 1076-1084 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T11 | 1582-1591 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T12 | 1743-1747 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 106-107 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T2 | 634-641 | http://purl.obolibrary.org/obo/CLO_0009985 | denotes | focuses |
| T3 | 1392-1395 | http://purl.obolibrary.org/obo/CLO_0050884 | denotes | ten |
| T4 | 1430-1433 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T5 | 1529-1532 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T6 | 1636-1646 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1 | 538-553 | Chemical | denotes | anti-viral drug | http://purl.obolibrary.org/obo/CHEBI_36044 |
| T2 | 549-553 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T3 | 778-793 | Chemical | denotes | corticosteroids | http://purl.obolibrary.org/obo/CHEBI_50858 |
| T4 | 840-850 | Chemical | denotes | interferon | http://purl.obolibrary.org/obo/CHEBI_52999 |
| T5 | 1169-1186 | Chemical | denotes | anti-viral agents | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T6 | 1198-1209 | Chemical | denotes | oseltamivir | http://purl.obolibrary.org/obo/CHEBI_7798 |
| T7 | 1237-1248 | Chemical | denotes | ganciclovir | http://purl.obolibrary.org/obo/CHEBI_465284 |
| T8 | 1288-1307 | Chemical | denotes | lopinavir/ritonavir | http://purl.obolibrary.org/obo/CHEBI_145924 |
| T9 | 1288-1297 | Chemical | denotes | lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
| T10 | 1298-1307 | Chemical | denotes | ritonavir | http://purl.obolibrary.org/obo/CHEBI_45409 |
| T11 | 1506-1517 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
| T12 | 1518-1527 | Chemical | denotes | phosphate | http://purl.obolibrary.org/obo/CHEBI_18367|http://purl.obolibrary.org/obo/CHEBI_26020|http://purl.obolibrary.org/obo/CHEBI_35780|http://purl.obolibrary.org/obo/CHEBI_43474 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 193-202 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
| T2 | 402-411 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
| T3 | 461-481 | Phenotype | denotes | respiratory distress | http://purl.obolibrary.org/obo/HP_0002098 |
| T4 | 1582-1591 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2 | 0-31 | Sentence | denotes | Challenges in treating COVID-19 |
| T3 | 32-239 | Sentence | denotes | Coronavirus disease (COVID-19), which appeared in December 2019, presents a global challenge, particularly in the rapid increase of critically ill patients with pneumonia and absence of definitive treatment. |
| T4 | 240-310 | Sentence | denotes | To date, over 81,000 cases have been confirmed, with over 2700 deaths. |
| T5 | 311-495 | Sentence | denotes | The mortality appears to be around 2%; early published data indicate 25.9% with SARS-CoV-2 pneumonia required ICU admission and 20.1% developed acute respiratory distress syndrome [1]. |
| T6 | 496-599 | Sentence | denotes | There is presently no vaccine or specific anti-viral drug regime used to treat critically ill patients. |
| T7 | 600-732 | Sentence | denotes | The management of patients mainly focuses on the provision of supportive care, e.g., oxygenation, ventilation, and fluid management. |
| T8 | 733-916 | Sentence | denotes | Combination treatment of low-dose systematic corticosteroids and anti-virals and atomization inhalation of interferon have been encouraged as part of critical COVID-19 management [2]. |
| T9 | 917-1036 | Sentence | denotes | Other reported therapeutic agents that are used for the treatment of seriously ill patients have been noted in Table 1. |
| T10 | 1037-1084 | Sentence | denotes | Table 1 Potential treatment options of COVID-19 |
| T11 | 1085-1130 | Sentence | denotes | Classes Potential treatment options Reference |
| T12 | 1131-1341 | Sentence | denotes | Anti-viral > 85% of patients received anti-viral agents, including oseltamivir (75 mg every 12 h orally), ganciclovir (0.25 g every 12 h intravenously), and lopinavir/ritonavir tablets (400/100 mg twice daily). |
| T13 | 1342-1469 | Sentence | denotes | Remdesivir is currently under trials at more than ten medical institutions in Wuhan and has been known to prevent MERS-CoV. [1] |
| T14 | 1470-1651 | Sentence | denotes | Anti-malarial An old anti-malarial, chloroquine phosphate, has been effective in inhibiting the exacerbation of pneumonia due to its anti-viral and anti-inflammatory activities. [3] |
| T15 | 1652-1801 | Sentence | denotes | Herbal treatments There was widespread use of Traditional Chinese Medicine during the last SARS-COV outbreak and it is currently being used in China. |
| T16 | 1802-2018 | Sentence | denotes | The five most commonly used herbs were Astragali Radix (Huangqi), Glycyrrhizae Radix Et Rhizoma (Gancao), Saposhnikoviae Radix (Fangfeng), Atractylodis Macrocephalae Rhizoma (Baizhu), and Lonicerae Japonicae Flo. [4] |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32178711-32081636-23646622 | 492-493 | 32081636 | denotes | 1 |
| 32178711-32070391-23646623 | 913-914 | 32070391 | denotes | 2 |
| 32178711-32081636-23646624 | 1467-1468 | 32081636 | denotes | 1 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 3 | 23-31 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 13 | 179-187 | Species | denotes | patients | Tax:9606 |
| 14 | 32-51 | Disease | denotes | Coronavirus disease | MESH:D018352 |
| 15 | 53-61 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 16 | 164-178 | Disease | denotes | critically ill | MESH:D016638 |
| 17 | 193-202 | Disease | denotes | pneumonia | MESH:D011014 |
| 18 | 303-309 | Disease | denotes | deaths | MESH:D003643 |
| 19 | 315-324 | Disease | denotes | mortality | MESH:D003643 |
| 20 | 391-411 | Disease | denotes | SARS-CoV-2 pneumonia | MESH:C000657245 |
| 21 | 455-490 | Disease | denotes | acute respiratory distress syndrome | MESH:D012128 |
| 32 | 1743-1751 | Species | denotes | SARS-COV | Tax:694009 |
| 33 | 1151-1159 | Species | denotes | patients | Tax:9606 |
| 34 | 1456-1464 | Species | denotes | MERS-CoV | Tax:1335626 |
| 35 | 1198-1209 | Chemical | denotes | oseltamivir | MESH:D053139 |
| 36 | 1237-1248 | Chemical | denotes | ganciclovir | MESH:D015774 |
| 37 | 1288-1307 | Chemical | denotes | lopinavir/ritonavir | MESH:C558899 |
| 38 | 1342-1352 | Chemical | denotes | Remdesivir | MESH:C000606551 |
| 39 | 1506-1527 | Chemical | denotes | chloroquine phosphate | MESH:C023676 |
| 40 | 1582-1591 | Disease | denotes | pneumonia | MESH:D011014 |
| 41 | 1954-1975 | Disease | denotes | Macrocephalae Rhizoma | |
| 43 | 1076-1084 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 49 | 590-598 | Species | denotes | patients | Tax:9606 |
| 50 | 618-626 | Species | denotes | patients | Tax:9606 |
| 51 | 1000-1008 | Species | denotes | patients | Tax:9606 |
| 52 | 575-589 | Disease | denotes | critically ill | MESH:D016638 |
| 53 | 892-900 | Disease | denotes | COVID-19 | MESH:C000657245 |