PMC:7075884 / 527-999 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"49","span":{"begin":125,"end":144},"obj":"Gene"},{"id":"53","span":{"begin":255,"end":282},"obj":"Species"},{"id":"54","span":{"begin":284,"end":289},"obj":"Species"},{"id":"55","span":{"begin":390,"end":411},"obj":"Species"},{"id":"56","span":{"begin":442,"end":452},"obj":"Species"},{"id":"57","span":{"begin":454,"end":458},"obj":"Species"},{"id":"70","span":{"begin":413,"end":417},"obj":"Species"},{"id":"80","span":{"begin":243,"end":245},"obj":"Chemical"},{"id":"81","span":{"begin":378,"end":380},"obj":"Chemical"},{"id":"85","span":{"begin":460,"end":469},"obj":"Disease"}],"attributes":[{"id":"A49","pred":"tao:has_database_id","subj":"49","obj":"Gene:2194"},{"id":"A53","pred":"tao:has_database_id","subj":"53","obj":"Tax:10298"},{"id":"A54","pred":"tao:has_database_id","subj":"54","obj":"Tax:10298"},{"id":"A55","pred":"tao:has_database_id","subj":"55","obj":"Tax:10359"},{"id":"A56","pred":"tao:has_database_id","subj":"56","obj":"Tax:64320"},{"id":"A57","pred":"tao:has_database_id","subj":"57","obj":"Tax:64320"},{"id":"A70","pred":"tao:has_database_id","subj":"70","obj":"Tax:10359"},{"id":"A80","pred":"tao:has_database_id","subj":"80","obj":"MESH:C112485"},{"id":"A81","pred":"tao:has_database_id","subj":"81","obj":"MESH:C112485"},{"id":"A85","pred":"tao:has_database_id","subj":"85","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"ctivity have been suggested including: SUMOylation inhibition; blocking formation of the E1-SUMO intermediate; inhibition of fatty acid synthase; non-specific SIRT inhibition; and activation of protein phosphatase type-2C. Here we report that GA inhibits Herpes simplex virus type 1 (HSV-1) by inhibition of both fusion and viral protein synthesis. Additionally, we report that GA inhibits human cytomegalovirus (HCMV) genome replication and Zika virus (ZIKV) infection of"}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T2","span":{"begin":125,"end":135},"obj":"Body_part"},{"id":"T3","span":{"begin":194,"end":201},"obj":"Body_part"},{"id":"T4","span":{"begin":330,"end":337},"obj":"Body_part"},{"id":"T5","span":{"begin":419,"end":425},"obj":"Body_part"}],"attributes":[{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma82738"},{"id":"A3","pred":"fma_id","subj":"T3","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A5","pred":"fma_id","subj":"T5","obj":"http://purl.org/sig/ont/fma/fma84116"}],"text":"ctivity have been suggested including: SUMOylation inhibition; blocking formation of the E1-SUMO intermediate; inhibition of fatty acid synthase; non-specific SIRT inhibition; and activation of protein phosphatase type-2C. Here we report that GA inhibits Herpes simplex virus type 1 (HSV-1) by inhibition of both fusion and viral protein synthesis. Additionally, we report that GA inhibits human cytomegalovirus (HCMV) genome replication and Zika virus (ZIKV) infection of"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T2","span":{"begin":255,"end":269},"obj":"Disease"},{"id":"T3","span":{"begin":442,"end":446},"obj":"Disease"},{"id":"T4","span":{"begin":460,"end":469},"obj":"Disease"}],"attributes":[{"id":"A2","pred":"mondo_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/MONDO_0004609"},{"id":"A3","pred":"mondo_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/MONDO_0018661"},{"id":"A4","pred":"mondo_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"ctivity have been suggested including: SUMOylation inhibition; blocking formation of the E1-SUMO intermediate; inhibition of fatty acid synthase; non-specific SIRT inhibition; and activation of protein phosphatase type-2C. Here we report that GA inhibits Herpes simplex virus type 1 (HSV-1) by inhibition of both fusion and viral protein synthesis. Additionally, we report that GA inhibits human cytomegalovirus (HCMV) genome replication and Zika virus (ZIKV) infection of"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T7","span":{"begin":89,"end":91},"obj":"http://purl.obolibrary.org/obo/CLO_0002857"},{"id":"T8","span":{"begin":180,"end":190},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T9","span":{"begin":270,"end":275},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T10","span":{"begin":390,"end":395},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T11","span":{"begin":447,"end":452},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"}],"text":"ctivity have been suggested including: SUMOylation inhibition; blocking formation of the E1-SUMO intermediate; inhibition of fatty acid synthase; non-specific SIRT inhibition; and activation of protein phosphatase type-2C. Here we report that GA inhibits Herpes simplex virus type 1 (HSV-1) by inhibition of both fusion and viral protein synthesis. Additionally, we report that GA inhibits human cytomegalovirus (HCMV) genome replication and Zika virus (ZIKV) infection of"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T14","span":{"begin":125,"end":135},"obj":"Chemical"},{"id":"T15","span":{"begin":131,"end":135},"obj":"Chemical"},{"id":"T16","span":{"begin":194,"end":201},"obj":"Chemical"},{"id":"T17","span":{"begin":243,"end":245},"obj":"Chemical"},{"id":"T20","span":{"begin":330,"end":337},"obj":"Chemical"},{"id":"T21","span":{"begin":378,"end":380},"obj":"Chemical"}],"attributes":[{"id":"A14","pred":"chebi_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_35366"},{"id":"A15","pred":"chebi_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A16","pred":"chebi_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A17","pred":"chebi_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_5206"},{"id":"A18","pred":"chebi_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_73855"},{"id":"A19","pred":"chebi_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_5354"},{"id":"A20","pred":"chebi_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A21","pred":"chebi_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/CHEBI_5206"},{"id":"A22","pred":"chebi_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/CHEBI_73855"},{"id":"A23","pred":"chebi_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/CHEBI_5354"}],"text":"ctivity have been suggested including: SUMOylation inhibition; blocking formation of the E1-SUMO intermediate; inhibition of fatty acid synthase; non-specific SIRT inhibition; and activation of protein phosphatase type-2C. Here we report that GA inhibits Herpes simplex virus type 1 (HSV-1) by inhibition of both fusion and viral protein synthesis. Additionally, we report that GA inhibits human cytomegalovirus (HCMV) genome replication and Zika virus (ZIKV) infection of"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T5","span":{"begin":39,"end":50},"obj":"http://purl.obolibrary.org/obo/GO_0016925"},{"id":"T6","span":{"begin":72,"end":81},"obj":"http://purl.obolibrary.org/obo/GO_0009058"},{"id":"T7","span":{"begin":202,"end":213},"obj":"http://purl.obolibrary.org/obo/GO_0016791"},{"id":"T8","span":{"begin":324,"end":347},"obj":"http://purl.obolibrary.org/obo/GO_0019081"},{"id":"T9","span":{"begin":330,"end":347},"obj":"http://purl.obolibrary.org/obo/GO_0006412"},{"id":"T10","span":{"begin":338,"end":347},"obj":"http://purl.obolibrary.org/obo/GO_0009058"}],"text":"ctivity have been suggested including: SUMOylation inhibition; blocking formation of the E1-SUMO intermediate; inhibition of fatty acid synthase; non-specific SIRT inhibition; and activation of protein phosphatase type-2C. Here we report that GA inhibits Herpes simplex virus type 1 (HSV-1) by inhibition of both fusion and viral protein synthesis. Additionally, we report that GA inhibits human cytomegalovirus (HCMV) genome replication and Zika virus (ZIKV) infection of"}

{"project":"LitCovid-sentences","denotations":[{"id":"T7","span":{"begin":223,"end":348},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"ctivity have been suggested including: SUMOylation inhibition; blocking formation of the E1-SUMO intermediate; inhibition of fatty acid synthase; non-specific SIRT inhibition; and activation of protein phosphatase type-2C. Here we report that GA inhibits Herpes simplex virus type 1 (HSV-1) by inhibition of both fusion and viral protein synthesis. Additionally, we report that GA inhibits human cytomegalovirus (HCMV) genome replication and Zika virus (ZIKV) infection of"}