PMC:7075884 / 1243-1715 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"62","span":{"begin":20,"end":30},"obj":"Species"},{"id":"63","span":{"begin":151,"end":156},"obj":"Species"},{"id":"64","span":{"begin":448,"end":459},"obj":"Species"},{"id":"65","span":{"begin":461,"end":465},"obj":"Species"},{"id":"66","span":{"begin":467,"end":471},"obj":"Species"},{"id":"82","span":{"begin":61,"end":63},"obj":"Chemical"},{"id":"83","span":{"begin":183,"end":185},"obj":"Chemical"},{"id":"84","span":{"begin":333,"end":335},"obj":"Chemical"},{"id":"86","span":{"begin":207,"end":216},"obj":"Disease"},{"id":"87","span":{"begin":339,"end":354},"obj":"Disease"},{"id":"88","span":{"begin":371,"end":380},"obj":"Disease"},{"id":"89","span":{"begin":431,"end":441},"obj":"Disease"}],"attributes":[{"id":"A62","pred":"tao:has_database_id","subj":"62","obj":"Tax:10508"},{"id":"A63","pred":"tao:has_database_id","subj":"63","obj":"Tax:10298"},{"id":"A64","pred":"tao:has_database_id","subj":"64","obj":"Tax:11118"},{"id":"A65","pred":"tao:has_database_id","subj":"65","obj":"Tax:1570291"},{"id":"A66","pred":"tao:has_database_id","subj":"66","obj":"Tax:64320"},{"id":"A82","pred":"tao:has_database_id","subj":"82","obj":"MESH:C112485"},{"id":"A83","pred":"tao:has_database_id","subj":"83","obj":"MESH:C112485"},{"id":"A84","pred":"tao:has_database_id","subj":"84","obj":"MESH:C112485"},{"id":"A86","pred":"tao:has_database_id","subj":"86","obj":"MESH:D007239"},{"id":"A87","pred":"tao:has_database_id","subj":"87","obj":"MESH:D001102"},{"id":"A88","pred":"tao:has_database_id","subj":"88","obj":"MESH:D007239"},{"id":"A89","pred":"tao:has_database_id","subj":"89","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":" of a non-enveloped adenovirus. Our experiments suggest that GA inhibits virion entry by blocking the initial fusion event. Data showing inhibition of HSV-1 and CMV replication, when GA is administered post-infection, suggest a possible secondary mechanism targeting protein and DNA synthesis. Thus, in light of the strong effect of GA on viral infection, even after the infection begins, it may potentially be used to treat acute infections (e.g. Coronavirus, EBOV, ZIKV,"}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T9","span":{"begin":267,"end":274},"obj":"Body_part"},{"id":"T10","span":{"begin":279,"end":282},"obj":"Body_part"}],"attributes":[{"id":"A9","pred":"fma_id","subj":"T9","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A10","pred":"fma_id","subj":"T10","obj":"http://purl.org/sig/ont/fma/fma74412"}],"text":" of a non-enveloped adenovirus. Our experiments suggest that GA inhibits virion entry by blocking the initial fusion event. Data showing inhibition of HSV-1 and CMV replication, when GA is administered post-infection, suggest a possible secondary mechanism targeting protein and DNA synthesis. Thus, in light of the strong effect of GA on viral infection, even after the infection begins, it may potentially be used to treat acute infections (e.g. Coronavirus, EBOV, ZIKV,"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T7","span":{"begin":207,"end":216},"obj":"Disease"},{"id":"T8","span":{"begin":339,"end":354},"obj":"Disease"},{"id":"T9","span":{"begin":345,"end":354},"obj":"Disease"},{"id":"T10","span":{"begin":371,"end":380},"obj":"Disease"},{"id":"T11","span":{"begin":431,"end":441},"obj":"Disease"}],"attributes":[{"id":"A7","pred":"mondo_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A8","pred":"mondo_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/MONDO_0005108"},{"id":"A9","pred":"mondo_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A10","pred":"mondo_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A11","pred":"mondo_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":" of a non-enveloped adenovirus. Our experiments suggest that GA inhibits virion entry by blocking the initial fusion event. Data showing inhibition of HSV-1 and CMV replication, when GA is administered post-infection, suggest a possible secondary mechanism targeting protein and DNA synthesis. Thus, in light of the strong effect of GA on viral infection, even after the infection begins, it may potentially be used to treat acute infections (e.g. Coronavirus, EBOV, ZIKV,"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T19","span":{"begin":4,"end":5},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T20","span":{"begin":226,"end":227},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":" of a non-enveloped adenovirus. Our experiments suggest that GA inhibits virion entry by blocking the initial fusion event. Data showing inhibition of HSV-1 and CMV replication, when GA is administered post-infection, suggest a possible secondary mechanism targeting protein and DNA synthesis. Thus, in light of the strong effect of GA on viral infection, even after the infection begins, it may potentially be used to treat acute infections (e.g. Coronavirus, EBOV, ZIKV,"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T28","span":{"begin":61,"end":63},"obj":"Chemical"},{"id":"T31","span":{"begin":183,"end":185},"obj":"Chemical"},{"id":"T34","span":{"begin":267,"end":274},"obj":"Chemical"},{"id":"T35","span":{"begin":279,"end":282},"obj":"Chemical"},{"id":"T36","span":{"begin":333,"end":335},"obj":"Chemical"}],"attributes":[{"id":"A28","pred":"chebi_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/CHEBI_5206"},{"id":"A29","pred":"chebi_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/CHEBI_73855"},{"id":"A30","pred":"chebi_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/CHEBI_5354"},{"id":"A31","pred":"chebi_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/CHEBI_5206"},{"id":"A32","pred":"chebi_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/CHEBI_73855"},{"id":"A33","pred":"chebi_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/CHEBI_5354"},{"id":"A34","pred":"chebi_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A35","pred":"chebi_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/CHEBI_16991"},{"id":"A36","pred":"chebi_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/CHEBI_5206"},{"id":"A37","pred":"chebi_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/CHEBI_73855"},{"id":"A38","pred":"chebi_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/CHEBI_5354"}],"text":" of a non-enveloped adenovirus. Our experiments suggest that GA inhibits virion entry by blocking the initial fusion event. Data showing inhibition of HSV-1 and CMV replication, when GA is administered post-infection, suggest a possible secondary mechanism targeting protein and DNA synthesis. Thus, in light of the strong effect of GA on viral infection, even after the infection begins, it may potentially be used to treat acute infections (e.g. Coronavirus, EBOV, ZIKV,"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T11","span":{"begin":279,"end":292},"obj":"http://purl.obolibrary.org/obo/GO_0071897"},{"id":"T12","span":{"begin":283,"end":292},"obj":"http://purl.obolibrary.org/obo/GO_0009058"},{"id":"T13","span":{"begin":339,"end":354},"obj":"http://purl.obolibrary.org/obo/GO_0016032"}],"text":" of a non-enveloped adenovirus. Our experiments suggest that GA inhibits virion entry by blocking the initial fusion event. Data showing inhibition of HSV-1 and CMV replication, when GA is administered post-infection, suggest a possible secondary mechanism targeting protein and DNA synthesis. Thus, in light of the strong effect of GA on viral infection, even after the infection begins, it may potentially be used to treat acute infections (e.g. Coronavirus, EBOV, ZIKV,"}

{"project":"LitCovid-sentences","denotations":[{"id":"T11","span":{"begin":32,"end":123},"obj":"Sentence"},{"id":"T12","span":{"begin":124,"end":293},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":" of a non-enveloped adenovirus. Our experiments suggest that GA inhibits virion entry by blocking the initial fusion event. Data showing inhibition of HSV-1 and CMV replication, when GA is administered post-infection, suggest a possible secondary mechanism targeting protein and DNA synthesis. Thus, in light of the strong effect of GA on viral infection, even after the infection begins, it may potentially be used to treat acute infections (e.g. Coronavirus, EBOV, ZIKV,"}